{"id":"https://openalex.org/W4223572452","doi":"https://doi.org/10.1371/journal.pcbi.1009982","title":"Ten simple rules for building a successful science start-up","display_name":"Ten simple rules for building a successful science start-up","publication_year":2022,"publication_date":"2022-04-07","ids":{"openalex":"https://openalex.org/W4223572452","doi":"https://doi.org/10.1371/journal.pcbi.1009982","pmid":"https://pubmed.ncbi.nlm.nih.gov/35389985"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pcbi.1009982","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1009982","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1009982&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},"type":"editorial","indexed_in":["crossref","datacite","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1009982&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5049895885","display_name":"Tobias Reichmuth","orcid":null},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Tobias Reichmuth","raw_affiliation_strings":["Maximon AG, Zug, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Maximon AG, Zug, Switzerland","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5080253914","display_name":"Collin Y. Ewald","orcid":"https://orcid.org/0000-0003-1166-4171"},"institutions":[{"id":"https://openalex.org/I35440088","display_name":"ETH Zurich","ror":"https://ror.org/05a28rw58","country_code":"CH","type":"education","lineage":["https://openalex.org/I2799323385","https://openalex.org/I35440088"]},{"id":"https://openalex.org/I5124864","display_name":"\u00c9cole Polytechnique F\u00e9d\u00e9rale de Lausanne","ror":"https://ror.org/02s376052","country_code":"CH","type":"education","lineage":["https://openalex.org/I2799323385","https://openalex.org/I5124864"]}],"countries":["CH"],"is_corresponding":true,"raw_author_name":"Collin Y. Ewald","raw_affiliation_strings":["Laboratory of Extracellular Matrix Regeneration, Institute of Translational Medicine, Department of Health Sciences and Technology, Swiss Federal Institute of Technology (ETH Z\u00fcrich), Schwerzenbach, Switzerland"],"raw_orcid":"https://orcid.org/0000-0003-1166-4171","affiliations":[{"raw_affiliation_string":"Laboratory of Extracellular Matrix Regeneration, Institute of Translational Medicine, Department of Health Sciences and Technology, Swiss Federal Institute of Technology (ETH Z\u00fcrich), Schwerzenbach, Switzerland","institution_ids":["https://openalex.org/I5124864","https://openalex.org/I35440088"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5049895885","https://openalex.org/A5080253914"],"corresponding_institution_ids":["https://openalex.org/I35440088","https://openalex.org/I5124864"],"apc_list":{"value":2655,"currency":"USD","value_usd":2655},"apc_paid":{"value":2655,"currency":"USD","value_usd":2655},"fwci":0.2453,"has_fulltext":true,"cited_by_count":4,"citation_normalized_percentile":{"value":0.45632724,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":98},"biblio":{"volume":"18","issue":"4","first_page":"e1009982","last_page":"e1009982"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13280","display_name":"Biomedical and Engineering Education","score":0.9521999955177307,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T13280","display_name":"Biomedical and Engineering Education","score":0.9521999955177307,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10058","display_name":"Entrepreneurship Studies and Influences","score":0.9452999830245972,"subfield":{"id":"https://openalex.org/subfields/1405","display_name":"Management of Technology and Innovation"},"field":{"id":"https://openalex.org/fields/14","display_name":"Business, Management and Accounting"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10726","display_name":"Career Development and Diversity","score":0.927299976348877,"subfield":{"id":"https://openalex.org/subfields/3311","display_name":"Safety Research"},"field":{"id":"https://openalex.org/fields/33","display_name":"Social Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/simple","display_name":"Simple (philosophy)","score":0.7219067215919495},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.4798114597797394},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.4659994840621948},{"id":"https://openalex.org/keywords/epistemology","display_name":"Epistemology","score":0.08304533362388611}],"concepts":[{"id":"https://openalex.org/C2780586882","wikidata":"https://www.wikidata.org/wiki/Q7520643","display_name":"Simple (philosophy)","level":2,"score":0.7219067215919495},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4798114597797394},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.4659994840621948},{"id":"https://openalex.org/C111472728","wikidata":"https://www.wikidata.org/wiki/Q9471","display_name":"Epistemology","level":1,"score":0.08304533362388611},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D003142","descriptor_name":"Communication","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003142","descriptor_name":"Communication","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003142","descriptor_name":"Communication","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012586","descriptor_name":"Science","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012586","descriptor_name":"Science","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012586","descriptor_name":"Science","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":7,"locations":[{"id":"doi:10.1371/journal.pcbi.1009982","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1009982","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1009982&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},{"id":"pmid:35389985","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35389985","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS computational biology","raw_type":null},{"id":"pmh:oai:RePEc:plo:pcbi00:1009982","is_oa":false,"landing_page_url":"https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1009982","pdf_url":null,"source":{"id":"https://openalex.org/S4306401271","display_name":"RePEc: Research Papers in Economics","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I77793887","host_organization_name":"Federal Reserve Bank of St. Louis","host_organization_lineage":["https://openalex.org/I77793887"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"},{"id":"pmh:oai:doaj.org/article:70eccab7d3df4c189f64708628779189","is_oa":true,"landing_page_url":"https://doaj.org/article/70eccab7d3df4c189f64708628779189","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Computational Biology, Vol 18, Iss 4, p e1009982 (2022)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:8989209","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8989209","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Comput Biol","raw_type":"Text"},{"id":"pmh:oai:www.research-collection.ethz.ch:20.500.11850/543993","is_oa":true,"landing_page_url":"http://hdl.handle.net/20.500.11850/543993","pdf_url":null,"source":{"id":"https://openalex.org/S4306402302","display_name":"Repository for Publications and Research Data (ETH Zurich)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I35440088","host_organization_name":"ETH Zurich","host_organization_lineage":["https://openalex.org/I35440088"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Computational Biology, 18 (4)","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"doi:10.3929/ethz-b-000543993","is_oa":true,"landing_page_url":"https://doi.org/10.3929/ethz-b-000543993","pdf_url":null,"source":{"id":"https://openalex.org/S7407051236","display_name":"ETH Z\u00fcrich Research Collection","issn_l":null,"issn":[],"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":null,"raw_source_name":null,"raw_type":"article-journal"}],"best_oa_location":{"id":"doi:10.1371/journal.pcbi.1009982","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1009982","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1009982&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G2948487697","display_name":null,"funder_award_id":"190072","funder_id":"https://openalex.org/F4320320924","funder_display_name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung"},{"id":"https://openalex.org/G6048673877","display_name":null,"funder_award_id":"SNF P3 Project 190072","funder_id":"https://openalex.org/F4320320924","funder_display_name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320320924","display_name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung","ror":"https://ror.org/00yjd3n13"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4223572452.pdf","grobid_xml":"https://content.openalex.org/works/W4223572452.grobid-xml"},"referenced_works_count":15,"referenced_works":["https://openalex.org/W19811004","https://openalex.org/W575598456","https://openalex.org/W622457466","https://openalex.org/W2011088550","https://openalex.org/W2032864321","https://openalex.org/W2558602025","https://openalex.org/W2736444177","https://openalex.org/W2796687980","https://openalex.org/W3112131385","https://openalex.org/W4236522208","https://openalex.org/W4243208105","https://openalex.org/W4302041990","https://openalex.org/W6619576424","https://openalex.org/W6721464462","https://openalex.org/W6750483259"],"related_works":["https://openalex.org/W2748952813","https://openalex.org/W1585007175","https://openalex.org/W2382521049","https://openalex.org/W2390279801","https://openalex.org/W2144385241","https://openalex.org/W2358668433","https://openalex.org/W2376932109","https://openalex.org/W2001405890","https://openalex.org/W2382290278","https://openalex.org/W2165950148"],"abstract_inverted_index":{"Certain":[0],"rules":[1,14,24,49,69,84],"do":[2],"apply":[3,70],"when":[4],"building":[5],"a":[6,35,62,96],"start-up":[7,74],"company.":[8],"The":[9,21],"core":[10],"principles":[11],"of":[12,37],"these":[13,68,83],"are":[15],"fundamental":[16],"across":[17],"industries,":[18],"including":[19],"academia.":[20],"following":[22],"10":[23],"guide":[25],"academic":[26],"researchers":[27],"and":[28,54,75,91],"business-trained":[29],"entrepreneurs":[30],"who":[31],"want":[32],"to":[33,39,57,71,94],"take":[34],"leap":[36],"faith":[38],"adopt":[40],"the":[41,78,87],"recent":[42],"advances":[43],"in":[44],"sciences":[45],"for":[46,61],"commercialization.":[47],"These":[48],"provide":[50],"an":[51],"entry":[52],"point":[53],"raise":[55],"challenges":[56],"be":[58],"thought":[59],"about":[60],"starting":[63],"entrepreneur.":[64],"We":[65],"believe":[66],"that":[67],"any":[72],"innovation-based":[73],"help":[76,86],"prioritize":[77],"most":[79],"impactful":[80],"tasks.":[81],"Understanding":[82],"will":[85],"founding":[88],"team,":[89],"investors,":[90],"other":[92],"stakeholders":[93],"launch":[95],"successful":[97],"start-up.":[98]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1}],"updated_date":"2026-01-13T01:12:25.745995","created_date":"2025-10-10T00:00:00"}
