{"id":"https://openalex.org/W4220932317","doi":"https://doi.org/10.1371/journal.pcbi.1009805","title":"A computationally tractable birth-death model that combines phylogenetic and epidemiological data","display_name":"A computationally tractable birth-death model that combines phylogenetic and epidemiological data","publication_year":2022,"publication_date":"2022-02-11","ids":{"openalex":"https://openalex.org/W4220932317","doi":"https://doi.org/10.1371/journal.pcbi.1009805","pmid":"https://pubmed.ncbi.nlm.nih.gov/35148311"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pcbi.1009805","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1009805","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1009805&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1009805&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5023336304","display_name":"Alexander E. Zarebski","orcid":"https://orcid.org/0000-0003-1824-7653"},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Alexander Eugene Zarebski","raw_affiliation_strings":["Department of Zoology, University of Oxford, Oxford, United Kingdom"],"raw_orcid":"https://orcid.org/0000-0003-1824-7653","affiliations":[{"raw_affiliation_string":"Department of Zoology, University of Oxford, Oxford, United Kingdom","institution_ids":["https://openalex.org/I40120149"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007000185","display_name":"Louis du Plessis","orcid":"https://orcid.org/0000-0003-0352-6289"},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Louis du Plessis","raw_affiliation_strings":["Department of Zoology, University of Oxford, Oxford, United Kingdom"],"raw_orcid":"https://orcid.org/0000-0003-0352-6289","affiliations":[{"raw_affiliation_string":"Department of Zoology, University of Oxford, Oxford, United Kingdom","institution_ids":["https://openalex.org/I40120149"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045686938","display_name":"Kris V. Parag","orcid":"https://orcid.org/0000-0002-7806-3605"},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Kris Varun Parag","raw_affiliation_strings":["MRC Centre for Global Infectious Disease Analysis, Imperial College London, London, United Kingdom"],"raw_orcid":"https://orcid.org/0000-0002-7806-3605","affiliations":[{"raw_affiliation_string":"MRC Centre for Global Infectious Disease Analysis, Imperial College London, London, United Kingdom","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5061658598","display_name":"Oliver G. Pybus","orcid":"https://orcid.org/0000-0002-8797-2667"},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Oliver George Pybus","raw_affiliation_strings":["Department of Zoology, University of Oxford, Oxford, United Kingdom"],"raw_orcid":"https://orcid.org/0000-0002-8797-2667","affiliations":[{"raw_affiliation_string":"Department of Zoology, University of Oxford, Oxford, United Kingdom","institution_ids":["https://openalex.org/I40120149"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5023336304"],"corresponding_institution_ids":["https://openalex.org/I40120149"],"apc_list":{"value":2655,"currency":"USD","value_usd":2655},"apc_paid":{"value":2655,"currency":"USD","value_usd":2655},"fwci":1.3019,"has_fulltext":true,"cited_by_count":15,"citation_normalized_percentile":{"value":0.7894012,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":96,"max":98},"biblio":{"volume":"18","issue":"2","first_page":"e1009805","last_page":"e1009805"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11764","display_name":"Evolution and Genetic Dynamics","score":0.9889000058174133,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11468","display_name":"Genetic Mapping and Diversity in Plants and Animals","score":0.9800999760627747,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/inference","display_name":"Inference","score":0.7034249305725098},{"id":"https://openalex.org/keywords/viral-phylodynamics","display_name":"Viral phylodynamics","score":0.6737947463989258},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6035307049751282},{"id":"https://openalex.org/keywords/robustness","display_name":"Robustness (evolution)","score":0.5837366580963135},{"id":"https://openalex.org/keywords/phylogenetic-tree","display_name":"Phylogenetic tree","score":0.45875027775764465},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.3643832206726074},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.3237205743789673},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.254372239112854},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.14254048466682434}],"concepts":[{"id":"https://openalex.org/C2776214188","wikidata":"https://www.wikidata.org/wiki/Q408386","display_name":"Inference","level":2,"score":0.7034249305725098},{"id":"https://openalex.org/C21833749","wikidata":"https://www.wikidata.org/wiki/Q7189431","display_name":"Viral phylodynamics","level":4,"score":0.6737947463989258},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6035307049751282},{"id":"https://openalex.org/C63479239","wikidata":"https://www.wikidata.org/wiki/Q7353546","display_name":"Robustness (evolution)","level":3,"score":0.5837366580963135},{"id":"https://openalex.org/C193252679","wikidata":"https://www.wikidata.org/wiki/Q242125","display_name":"Phylogenetic tree","level":3,"score":0.45875027775764465},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.3643832206726074},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3237205743789673},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.254372239112854},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.14254048466682434},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004196","descriptor_name":"Disease Outbreaks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004196","descriptor_name":"Disease Outbreaks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004196","descriptor_name":"Disease Outbreaks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004196","descriptor_name":"Disease Outbreaks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004196","descriptor_name":"Disease Outbreaks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010802","descriptor_name":"Phylogeny","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010802","descriptor_name":"Phylogeny","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010802","descriptor_name":"Phylogeny","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010802","descriptor_name":"Phylogeny","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010802","descriptor_name":"Phylogeny","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011336","descriptor_name":"Probability","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011336","descriptor_name":"Probability","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011336","descriptor_name":"Probability","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011336","descriptor_name":"Probability","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011336","descriptor_name":"Probability","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.1371/journal.pcbi.1009805","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1009805","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1009805&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},{"id":"pmid:35148311","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35148311","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS computational biology","raw_type":null},{"id":"pmh:oai:RePEc:plo:pcbi00:1009805","is_oa":false,"landing_page_url":"https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1009805","pdf_url":null,"source":{"id":"https://openalex.org/S4306401271","display_name":"RePEc: Research Papers in Economics","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I77793887","host_organization_name":"Federal Reserve Bank of St. Louis","host_organization_lineage":["https://openalex.org/I77793887"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"},{"id":"pmh:oai:doaj.org/article:d2b798ffd62544e8bcbec69ae855e43e","is_oa":true,"landing_page_url":"https://doaj.org/article/d2b798ffd62544e8bcbec69ae855e43e","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Computational Biology, Vol 18, Iss 2, p e1009805 (2022)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:8903285","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8903285","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Comput Biol","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1371/journal.pcbi.1009805","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1009805","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1009805&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.8399999737739563,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"awards":[{"id":"https://openalex.org/G2740751069","display_name":"MRC Centre for Global Infectious Disease Analysis","funder_award_id":"MR/R015600/1","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G6520098237","display_name":null,"funder_award_id":"MR/R015600/1","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G8266328","display_name":null,"funder_award_id":"MR/S019693/1","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"}],"funders":[{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4220932317.pdf","grobid_xml":"https://content.openalex.org/works/W4220932317.grobid-xml"},"referenced_works_count":50,"referenced_works":["https://openalex.org/W73440584","https://openalex.org/W1501586228","https://openalex.org/W1548037568","https://openalex.org/W1963568208","https://openalex.org/W1979257831","https://openalex.org/W1984454437","https://openalex.org/W1993210385","https://openalex.org/W2004506270","https://openalex.org/W2007593785","https://openalex.org/W2038427571","https://openalex.org/W2055041101","https://openalex.org/W2087133785","https://openalex.org/W2096239531","https://openalex.org/W2098062910","https://openalex.org/W2102187991","https://openalex.org/W2103148043","https://openalex.org/W2106565812","https://openalex.org/W2122980269","https://openalex.org/W2133979592","https://openalex.org/W2148963653","https://openalex.org/W2153613691","https://openalex.org/W2154552181","https://openalex.org/W2156358357","https://openalex.org/W2160253520","https://openalex.org/W2163357043","https://openalex.org/W2178385094","https://openalex.org/W2242437964","https://openalex.org/W2276895023","https://openalex.org/W2319462502","https://openalex.org/W2334380117","https://openalex.org/W2735509167","https://openalex.org/W2901174607","https://openalex.org/W2916198760","https://openalex.org/W2944032254","https://openalex.org/W2995358823","https://openalex.org/W3003424289","https://openalex.org/W3019397786","https://openalex.org/W3024845823","https://openalex.org/W3046148328","https://openalex.org/W3085126325","https://openalex.org/W3098202346","https://openalex.org/W3102002539","https://openalex.org/W3119321472","https://openalex.org/W3121700827","https://openalex.org/W3137008901","https://openalex.org/W3158148925","https://openalex.org/W3161806733","https://openalex.org/W3174244217","https://openalex.org/W4239975174","https://openalex.org/W4390591069"],"related_works":["https://openalex.org/W2622640614","https://openalex.org/W4385751614","https://openalex.org/W2148594363","https://openalex.org/W4379094465","https://openalex.org/W4313492089","https://openalex.org/W3161238707","https://openalex.org/W2927109576","https://openalex.org/W4285325032","https://openalex.org/W2890796073","https://openalex.org/W2096085713"],"abstract_inverted_index":{"Inferring":[0],"the":[1,36,42,68,72,115,123,126,145,155,164],"dynamics":[2,143],"of":[3,27,35,48,67,74,112,118,125,138,141,166],"pathogen":[4],"transmission":[5,69,142],"during":[6],"an":[7,10],"outbreak":[8],"is":[9,120,184],"important":[11,186],"problem":[12],"in":[13,31,122],"infectious":[14],"disease":[15],"epidemiology.":[16],"In":[17],"mathematical":[18],"epidemiology,":[19],"estimates":[20,66,137],"are":[21,41,80,87],"often":[22],"informed":[23],"by":[24],"time":[25],"series":[26],"confirmed":[28],"cases,":[29],"while":[30],"phylodynamics":[32],"genetic":[33],"sequences":[34],"pathogen,":[37],"sampled":[38],"through":[39],"time,":[40],"primary":[43],"data":[44,49,62,134],"source.":[45],"Each":[46],"type":[47],"provides":[50],"different,":[51],"and":[52,71,84,86,106,132,144,169],"potentially":[53],"complementary,":[54],"insight.":[55],"Recent":[56],"studies":[57],"have":[58],"recognised":[59],"that":[60,154],"combining":[61],"sources":[63],"can":[64],"improve":[65],"rate":[70],"number":[73],"infected":[75],"individuals.":[76],"However,":[77],"inference":[78,179],"methods":[79],"typically":[81],"highly":[82],"specialised":[83],"field-specific":[85],"either":[88],"computationally":[89],"prohibitive":[90],"or":[91],"require":[92],"intensive":[93],"simulation,":[94],"limiting":[95],"their":[96],"real-time":[97],"utility.":[98],"We":[99],"present":[100],"a":[101,108],"novel":[102],"birth-death":[103],"phylogenetic":[104],"model":[105,174],"derive":[107],"tractable":[109],"analytic":[110],"approximation":[111,156,177],"its":[113],"likelihood,":[114],"computational":[116],"complexity":[117,168],"which":[119,183],"linear":[121,167],"size":[124],"dataset.":[127],"This":[128,176],"approach":[129],"combines":[130],"epidemiological":[131],"phylodynamic":[133],"to":[135,173],"produce":[136],"key":[139],"parameters":[140],"unobserved":[146],"prevalence.":[147],"Using":[148],"simulated":[149],"data,":[150],"we":[151],"show":[152],"(a)":[153],"agrees":[157],"well":[158],"with":[159],"existing":[160],"methods,":[161],"(b)":[162],"validate":[163],"claim":[165],"(c)":[170],"explore":[171],"robustness":[172],"misspecification.":[175],"facilitates":[178],"on":[180],"large":[181,188],"datasets,":[182],"increasingly":[185],"as":[187],"genomic":[189],"sequence":[190],"datasets":[191],"become":[192],"commonplace.":[193]},"counts_by_year":[{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":3}],"updated_date":"2026-01-13T01:12:25.745995","created_date":"2025-10-10T00:00:00"}