{"id":"https://openalex.org/W4200610607","doi":"https://doi.org/10.1371/journal.pcbi.1009690","title":"Multiscale model for forecasting Sabin 2 vaccine virus household and community transmission","display_name":"Multiscale model for forecasting Sabin 2 vaccine virus household and community transmission","publication_year":2021,"publication_date":"2021-12-21","ids":{"openalex":"https://openalex.org/W4200610607","doi":"https://doi.org/10.1371/journal.pcbi.1009690","pmid":"https://pubmed.ncbi.nlm.nih.gov/34932560"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pcbi.1009690","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1009690","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1009690&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1009690&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5089906522","display_name":"Michael Famulare","orcid":"https://orcid.org/0000-0001-9275-7454"},"institutions":[{"id":"https://openalex.org/I4210108985","display_name":"Bellevue Hospital Center","ror":"https://ror.org/01ky34z31","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1283621791","https://openalex.org/I4210086933","https://openalex.org/I4210108985"]},{"id":"https://openalex.org/I4210161429","display_name":"Intellectual Ventures (United States)","ror":"https://ror.org/05evsnd79","country_code":"US","type":"company","lineage":["https://openalex.org/I4210161429"]},{"id":"https://openalex.org/I4210161647","display_name":"Institute for Disease Modeling","ror":"https://ror.org/0532gcg76","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210161647"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael Famulare","raw_affiliation_strings":["Institute for Disease Modeling, Global Good, Intellectual Ventures, Bellevue, Washington, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Disease Modeling, Global Good, Intellectual Ventures, Bellevue, Washington, United States of America","institution_ids":["https://openalex.org/I4210161429","https://openalex.org/I4210108985","https://openalex.org/I4210161647"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082040261","display_name":"Wesley Wong","orcid":"https://orcid.org/0000-0001-5664-7143"},"institutions":[{"id":"https://openalex.org/I4210108985","display_name":"Bellevue Hospital Center","ror":"https://ror.org/01ky34z31","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1283621791","https://openalex.org/I4210086933","https://openalex.org/I4210108985"]},{"id":"https://openalex.org/I4210161429","display_name":"Intellectual Ventures (United States)","ror":"https://ror.org/05evsnd79","country_code":"US","type":"company","lineage":["https://openalex.org/I4210161429"]},{"id":"https://openalex.org/I4210161647","display_name":"Institute for Disease Modeling","ror":"https://ror.org/0532gcg76","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210161647"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wesley Wong","raw_affiliation_strings":["Institute for Disease Modeling, Global Good, Intellectual Ventures, Bellevue, Washington, United States of America"],"raw_orcid":"https://orcid.org/0000-0001-5664-7143","affiliations":[{"raw_affiliation_string":"Institute for Disease Modeling, Global Good, Intellectual Ventures, Bellevue, Washington, United States of America","institution_ids":["https://openalex.org/I4210161429","https://openalex.org/I4210108985","https://openalex.org/I4210161647"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068198671","display_name":"Rashidul Haque","orcid":"https://orcid.org/0000-0001-5100-136X"},"institutions":[{"id":"https://openalex.org/I205889620","display_name":"International Centre for Diarrhoeal Disease Research","ror":"https://ror.org/04vsvr128","country_code":"BD","type":"facility","lineage":["https://openalex.org/I205889620"]}],"countries":["BD"],"is_corresponding":false,"raw_author_name":"Rashidul Haque","raw_affiliation_strings":["International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh"],"raw_orcid":"https://orcid.org/0000-0001-5100-136X","affiliations":[{"raw_affiliation_string":"International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh","institution_ids":["https://openalex.org/I205889620"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051818098","display_name":"James A Platts-Mills","orcid":"https://orcid.org/0000-0002-4956-0418"},"institutions":[{"id":"https://openalex.org/I51556381","display_name":"University of Virginia","ror":"https://ror.org/0153tk833","country_code":"US","type":"education","lineage":["https://openalex.org/I51556381"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James A. Platts-Mills","raw_affiliation_strings":["Department of Medicine, Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, Virginia, United States of America"],"raw_orcid":"https://orcid.org/0000-0002-4956-0418","affiliations":[{"raw_affiliation_string":"Department of Medicine, Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, Virginia, United States of America","institution_ids":["https://openalex.org/I51556381"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082304127","display_name":"Parimalendu Saha","orcid":"https://orcid.org/0000-0002-2987-7493"},"institutions":[{"id":"https://openalex.org/I205889620","display_name":"International Centre for Diarrhoeal Disease Research","ror":"https://ror.org/04vsvr128","country_code":"BD","type":"facility","lineage":["https://openalex.org/I205889620"]}],"countries":["BD"],"is_corresponding":false,"raw_author_name":"Parimalendu Saha","raw_affiliation_strings":["International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh"],"raw_orcid":"https://orcid.org/0000-0002-2987-7493","affiliations":[{"raw_affiliation_string":"International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh","institution_ids":["https://openalex.org/I205889620"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050660259","display_name":"Asma Binte Aziz","orcid":"https://orcid.org/0000-0003-0203-5744"},"institutions":[{"id":"https://openalex.org/I205889620","display_name":"International Centre for Diarrhoeal Disease Research","ror":"https://ror.org/04vsvr128","country_code":"BD","type":"facility","lineage":["https://openalex.org/I205889620"]}],"countries":["BD"],"is_corresponding":false,"raw_author_name":"Asma B. Aziz","raw_affiliation_strings":["International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh","institution_ids":["https://openalex.org/I205889620"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016085568","display_name":"Tahmina Ahmed","orcid":"https://orcid.org/0000-0001-7534-4033"},"institutions":[{"id":"https://openalex.org/I205889620","display_name":"International Centre for Diarrhoeal Disease Research","ror":"https://ror.org/04vsvr128","country_code":"BD","type":"facility","lineage":["https://openalex.org/I205889620"]}],"countries":["BD"],"is_corresponding":false,"raw_author_name":"Tahmina Ahmed","raw_affiliation_strings":["International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh"],"raw_orcid":"https://orcid.org/0000-0001-7534-4033","affiliations":[{"raw_affiliation_string":"International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh","institution_ids":["https://openalex.org/I205889620"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048723336","display_name":"Md Ohedul Islam","orcid":"https://orcid.org/0000-0002-3403-6736"},"institutions":[{"id":"https://openalex.org/I205889620","display_name":"International Centre for Diarrhoeal Disease Research","ror":"https://ror.org/04vsvr128","country_code":"BD","type":"facility","lineage":["https://openalex.org/I205889620"]}],"countries":["BD"],"is_corresponding":false,"raw_author_name":"Md Ohedul Islam","raw_affiliation_strings":["International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh"],"raw_orcid":"https://orcid.org/0000-0002-3403-6736","affiliations":[{"raw_affiliation_string":"International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh","institution_ids":["https://openalex.org/I205889620"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101581076","display_name":"Md. Jashim Uddin","orcid":"https://orcid.org/0000-0002-2466-7198"},"institutions":[{"id":"https://openalex.org/I51556381","display_name":"University of Virginia","ror":"https://ror.org/0153tk833","country_code":"US","type":"education","lineage":["https://openalex.org/I51556381"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Md Jashim Uddin","raw_affiliation_strings":["Department of Medicine, Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, Virginia, United States of America"],"raw_orcid":"https://orcid.org/0000-0002-2466-7198","affiliations":[{"raw_affiliation_string":"Department of Medicine, Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, Virginia, United States of America","institution_ids":["https://openalex.org/I51556381"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010655685","display_name":"Ananda S Bandyopadhyay","orcid":"https://orcid.org/0000-0002-8395-2001"},"institutions":[{"id":"https://openalex.org/I1303444417","display_name":"Gates Foundation","ror":"https://ror.org/0456r8d26","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1303444417"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ananda S. Bandyopadhyay","raw_affiliation_strings":["Bill & Melinda Gates Foundation, Seattle, Washington, United States of America"],"raw_orcid":"https://orcid.org/0000-0002-8395-2001","affiliations":[{"raw_affiliation_string":"Bill & Melinda Gates Foundation, Seattle, Washington, United States of America","institution_ids":["https://openalex.org/I1303444417"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074136196","display_name":"Mohammad Yunus","orcid":"https://orcid.org/0000-0003-1116-4978"},"institutions":[{"id":"https://openalex.org/I205889620","display_name":"International Centre for Diarrhoeal Disease Research","ror":"https://ror.org/04vsvr128","country_code":"BD","type":"facility","lineage":["https://openalex.org/I205889620"]}],"countries":["BD"],"is_corresponding":false,"raw_author_name":"Mohammed Yunus","raw_affiliation_strings":["International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh","institution_ids":["https://openalex.org/I205889620"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084092871","display_name":"Khalequ Zaman","orcid":"https://orcid.org/0000-0002-1982-6879"},"institutions":[{"id":"https://openalex.org/I205889620","display_name":"International Centre for Diarrhoeal Disease Research","ror":"https://ror.org/04vsvr128","country_code":"BD","type":"facility","lineage":["https://openalex.org/I205889620"]}],"countries":["BD"],"is_corresponding":false,"raw_author_name":"Khalequ Zaman","raw_affiliation_strings":["International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh","institution_ids":["https://openalex.org/I205889620"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5051998945","display_name":"Mami Taniuchi","orcid":null},"institutions":[{"id":"https://openalex.org/I4210116219","display_name":"Engineering Systems (United States)","ror":"https://ror.org/02qg60849","country_code":"US","type":"company","lineage":["https://openalex.org/I4210116219"]},{"id":"https://openalex.org/I51556381","display_name":"University of Virginia","ror":"https://ror.org/0153tk833","country_code":"US","type":"education","lineage":["https://openalex.org/I51556381"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Mami Taniuchi","raw_affiliation_strings":["Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, United States of America","Department of Engineering Systems and Environment, University of Virginia, Charlottesville, Virginia, United States of America","Department of Medicine, Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, Virginia, United States of America"],"raw_orcid":"https://orcid.org/0000-0002-7559-1998","affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, United States of America","institution_ids":["https://openalex.org/I51556381"]},{"raw_affiliation_string":"Department of Engineering Systems and Environment, University of Virginia, Charlottesville, Virginia, United States of America","institution_ids":["https://openalex.org/I4210116219","https://openalex.org/I51556381"]},{"raw_affiliation_string":"Department of Medicine, Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, Virginia, United States of America","institution_ids":["https://openalex.org/I51556381"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":13,"corresponding_author_ids":["https://openalex.org/A5051998945"],"corresponding_institution_ids":["https://openalex.org/I4210116219","https://openalex.org/I51556381"],"apc_list":{"value":2655,"currency":"USD","value_usd":2655},"apc_paid":{"value":2199,"currency":"EUR","value_usd":2371},"fwci":1.1124,"has_fulltext":true,"cited_by_count":7,"citation_normalized_percentile":{"value":0.80407619,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":98},"biblio":{"volume":"17","issue":"12","first_page":"e1009690","last_page":"e1009690"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11112","display_name":"Viral Infections and Immunology Research","score":0.9983999729156494,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11112","display_name":"Viral Infections and Immunology Research","score":0.9983999729156494,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11243","display_name":"Respiratory viral infections research","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10410","display_name":"COVID-19 epidemiological studies","score":0.9944999814033508,"subfield":{"id":"https://openalex.org/subfields/2611","display_name":"Modeling and Simulation"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/transmission","display_name":"Transmission (telecommunications)","score":0.7938946485519409},{"id":"https://openalex.org/keywords/poliovirus","display_name":"Poliovirus","score":0.7301750779151917},{"id":"https://openalex.org/keywords/poliomyelitis-eradication","display_name":"Poliomyelitis eradication","score":0.6386127471923828},{"id":"https://openalex.org/keywords/poliomyelitis","display_name":"Poliomyelitis","score":0.6271411776542664},{"id":"https://openalex.org/keywords/vaccination","display_name":"Vaccination","score":0.6044964790344238},{"id":"https://openalex.org/keywords/herd-immunity","display_name":"Herd immunity","score":0.5795949101448059},{"id":"https://openalex.org/keywords/environmental-health","display_name":"Environmental health","score":0.5654754638671875},{"id":"https://openalex.org/keywords/outbreak","display_name":"Outbreak","score":0.5571630001068115},{"id":"https://openalex.org/keywords/virology","display_name":"Virology","score":0.4857945442199707},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.4774939715862274},{"id":"https://openalex.org/keywords/virus","display_name":"Virus","score":0.22942256927490234},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.21706673502922058},{"id":"https://openalex.org/keywords/telecommunications","display_name":"Telecommunications","score":0.08794432878494263}],"concepts":[{"id":"https://openalex.org/C761482","wikidata":"https://www.wikidata.org/wiki/Q118093","display_name":"Transmission (telecommunications)","level":2,"score":0.7938946485519409},{"id":"https://openalex.org/C2779631682","wikidata":"https://www.wikidata.org/wiki/Q12438936","display_name":"Poliovirus","level":3,"score":0.7301750779151917},{"id":"https://openalex.org/C151492266","wikidata":"https://www.wikidata.org/wiki/Q7209788","display_name":"Poliomyelitis eradication","level":4,"score":0.6386127471923828},{"id":"https://openalex.org/C4870876","wikidata":"https://www.wikidata.org/wiki/Q12195","display_name":"Poliomyelitis","level":2,"score":0.6271411776542664},{"id":"https://openalex.org/C22070199","wikidata":"https://www.wikidata.org/wiki/Q192995","display_name":"Vaccination","level":2,"score":0.6044964790344238},{"id":"https://openalex.org/C106192422","wikidata":"https://www.wikidata.org/wiki/Q736798","display_name":"Herd immunity","level":3,"score":0.5795949101448059},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.5654754638671875},{"id":"https://openalex.org/C116675565","wikidata":"https://www.wikidata.org/wiki/Q3241045","display_name":"Outbreak","level":2,"score":0.5571630001068115},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.4857945442199707},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4774939715862274},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.22942256927490234},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.21706673502922058},{"id":"https://openalex.org/C76155785","wikidata":"https://www.wikidata.org/wiki/Q418","display_name":"Telecommunications","level":1,"score":0.08794432878494263}],"mesh":[{"descriptor_ui":"D001459","descriptor_name":"Bangladesh","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001459","descriptor_name":"Bangladesh","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001459","descriptor_name":"Bangladesh","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011051","descriptor_name":"Poliomyelitis","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D011051","descriptor_name":"Poliomyelitis","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D011051","descriptor_name":"Poliomyelitis","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D011051","descriptor_name":"Poliomyelitis","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D011051","descriptor_name":"Poliomyelitis","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D011051","descriptor_name":"Poliomyelitis","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D011051","descriptor_name":"Poliomyelitis","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D011051","descriptor_name":"Poliomyelitis","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D011051","descriptor_name":"Poliomyelitis","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D011055","descriptor_name":"Poliovirus Vaccine, Oral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011055","descriptor_name":"Poliovirus Vaccine, Oral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011055","descriptor_name":"Poliovirus Vaccine, Oral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016032","descriptor_name":"Randomized Controlled Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016032","descriptor_name":"Randomized Controlled Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016032","descriptor_name":"Randomized Controlled Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017955","descriptor_name":"Poliovirus","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017955","descriptor_name":"Poliovirus","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017955","descriptor_name":"Poliovirus","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D032541","descriptor_name":"Mass Vaccination","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false},{"descriptor_ui":"D032541","descriptor_name":"Mass Vaccination","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false},{"descriptor_ui":"D032541","descriptor_name":"Mass Vaccination","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1371/journal.pcbi.1009690","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1009690","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1009690&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},{"id":"pmid:34932560","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34932560","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS computational biology","raw_type":null},{"id":"pmh:oai:doaj.org/article:b91c22edc02447ccab047ebdc942d67b","is_oa":true,"landing_page_url":"https://doaj.org/article/b91c22edc02447ccab047ebdc942d67b","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Computational Biology, Vol 17, Iss 12, p e1009690 (2021)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:8726461","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8726461","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Comput Biol","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1371/journal.pcbi.1009690","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1009690","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1009690&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.7300000190734863}],"awards":[{"id":"https://openalex.org/G6586082768","display_name":null,"funder_award_id":"OPP1125451","funder_id":"https://openalex.org/F4320306137","funder_display_name":"Bill and Melinda Gates Foundation"}],"funders":[{"id":"https://openalex.org/F4320306137","display_name":"Bill and Melinda Gates Foundation","ror":"https://ror.org/0456r8d26"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4200610607.pdf","grobid_xml":"https://content.openalex.org/works/W4200610607.grobid-xml"},"referenced_works_count":33,"referenced_works":["https://openalex.org/W1763607569","https://openalex.org/W1990440779","https://openalex.org/W1992384670","https://openalex.org/W1999035888","https://openalex.org/W2011079327","https://openalex.org/W2015407849","https://openalex.org/W2044279009","https://openalex.org/W2057132961","https://openalex.org/W2079231030","https://openalex.org/W2103390652","https://openalex.org/W2130410946","https://openalex.org/W2159301256","https://openalex.org/W2217907370","https://openalex.org/W2308436730","https://openalex.org/W2416632226","https://openalex.org/W2463967992","https://openalex.org/W2546136880","https://openalex.org/W2726072167","https://openalex.org/W2799743080","https://openalex.org/W2811044226","https://openalex.org/W2889458573","https://openalex.org/W2897349083","https://openalex.org/W2944697060","https://openalex.org/W2948253547","https://openalex.org/W2951412666","https://openalex.org/W2986629155","https://openalex.org/W3007760530","https://openalex.org/W3012245583","https://openalex.org/W3019647694","https://openalex.org/W3046477973","https://openalex.org/W3095358806","https://openalex.org/W3125364671","https://openalex.org/W4383602848"],"related_works":["https://openalex.org/W2569804517","https://openalex.org/W3116671654","https://openalex.org/W2065410610","https://openalex.org/W2979477663","https://openalex.org/W1985204017","https://openalex.org/W2108539575","https://openalex.org/W2051740776","https://openalex.org/W4302038248","https://openalex.org/W982014063","https://openalex.org/W1822704478"],"abstract_inverted_index":{"Since":[0],"the":[1,14,57,95,115,153],"global":[2],"withdrawal":[3],"of":[4,59,66,145,174],"Sabin":[5,68,91],"2":[6,27,69,92],"oral":[7],"poliovirus":[8,25,121,146,160],"vaccine":[9,41],"(OPV)":[10],"from":[11,80],"routine":[12],"immunization,":[13],"Global":[15],"Polio":[16],"Eradication":[17],"Initiative":[18],"(GPEI)":[19],"has":[20],"reported":[21],"multiple":[22],"circulating":[23],"vaccine-derived":[24],"type":[26],"(cVDPV2)":[28],"outbreaks.":[29],"Here,":[30],"we":[31,62],"generated":[32,117],"an":[33,87,124,171],"agent-based,":[34],"mechanistic":[35],"model":[36,116],"designed":[37],"to":[38,191],"assess":[39],"OPV-related":[40,179],"virus":[42],"transmission":[43,70,93,122,175,180],"risk":[44,181],"in":[45,71],"populations":[46],"with":[47,201],"heterogeneous":[48,104],"immunity,":[49],"demography,":[50],"and":[51,82,110,156,167,182],"social":[52],"mixing":[53],"patterns.":[54],"To":[55],"showcase":[56],"utility":[58],"our":[60],"model,":[61],"present":[63],"a":[64,184],"simulation":[65],"mOPV2-related":[67],"rural":[72],"Matlab,":[73],"Bangladesh":[74],"based":[75,107],"on":[76,108],"stool":[77],"samples":[78],"collected":[79],"infants":[81],"their":[83],"household":[84,109,166],"contacts":[85],"during":[86],"mOPV2":[88,96],"clinical":[89,97,154],"trial.":[90],"following":[94,123],"trial":[98,155,198],"was":[99],"replicated":[100],"by":[101],"specifying":[102],"multiple,":[103],"contact":[105,138],"rates":[106,139],"community":[111,168],"membership.":[112],"Once":[113],"calibrated,":[114],"Matlab-specific":[118],"insights":[119],"regarding":[120],"accidental":[125],"point":[126],"importation":[127],"or":[128],"mass":[129],"vaccination":[130],"event.":[131],"We":[132],"also":[133],"show":[134],"that":[135],"assuming":[136],"homogeneous":[137],"(mass":[140],"action),":[141],"as":[142,170],"is":[143,199],"common":[144],"forecast":[147],"models,":[148],"does":[149],"not":[150],"accurately":[151],"represent":[152],"risks":[157],"overestimating":[158],"forecasted":[159],"outbreak":[161],"probability.":[162],"Our":[163],"study":[164],"identifies":[165],"structure":[169],"important":[172],"source":[173],"heterogeneity":[176],"when":[177],"assessing":[178],"provides":[183],"calibratable":[185],"framework":[186],"for":[187],"expanding":[188],"these":[189],"analyses":[190],"other":[192],"populations.":[193],"Trial":[194],"Registration:":[195],"ClinicalTrials.gov":[196],"This":[197],"registered":[200],"clinicaltrials.gov,":[202],"NCT02477046.":[203]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":5}],"updated_date":"2026-05-06T08:25:59.206177","created_date":"2025-10-10T00:00:00"}