{"id":"https://openalex.org/W3181378126","doi":"https://doi.org/10.1371/journal.pcbi.1009129","title":"On the influence of prior information evaluated by fully Bayesian criteria in a personalized whole-brain model of epilepsy spread","display_name":"On the influence of prior information evaluated by fully Bayesian criteria in a personalized whole-brain model of epilepsy spread","publication_year":2021,"publication_date":"2021-07-14","ids":{"openalex":"https://openalex.org/W3181378126","doi":"https://doi.org/10.1371/journal.pcbi.1009129","mag":"3181378126","pmid":"https://pubmed.ncbi.nlm.nih.gov/34260596"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pcbi.1009129","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1009129","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1009129&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1009129&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5089498751","display_name":"Meysam Hashemi","orcid":"https://orcid.org/0000-0001-5289-9837"},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210110495","display_name":"Institut de Neurosciences des Syst\u00e8mes","ror":"https://ror.org/019kqby73","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I21491767","https://openalex.org/I4210087487","https://openalex.org/I4210110495"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Meysam Hashemi","raw_affiliation_strings":["Aix Marseille Univ, INSERM, INS, Inst Neurosci Syst, Marseille, France"],"raw_orcid":"https://orcid.org/0000-0001-5289-9837","affiliations":[{"raw_affiliation_string":"Aix Marseille Univ, INSERM, INS, Inst Neurosci Syst, Marseille, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210110495"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001863407","display_name":"Anirudh Nihalani Vattikonda","orcid":"https://orcid.org/0000-0001-7426-3872"},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210110495","display_name":"Institut de Neurosciences des Syst\u00e8mes","ror":"https://ror.org/019kqby73","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I21491767","https://openalex.org/I4210087487","https://openalex.org/I4210110495"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Anirudh N. Vattikonda","raw_affiliation_strings":["Aix Marseille Univ, INSERM, INS, Inst Neurosci Syst, Marseille, France"],"raw_orcid":"https://orcid.org/0000-0001-7426-3872","affiliations":[{"raw_affiliation_string":"Aix Marseille Univ, INSERM, INS, Inst Neurosci Syst, Marseille, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210110495"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020175733","display_name":"Viktor \u0160\u00ed\u0301p","orcid":"https://orcid.org/0000-0002-5006-9765"},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210110495","display_name":"Institut de Neurosciences des Syst\u00e8mes","ror":"https://ror.org/019kqby73","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I21491767","https://openalex.org/I4210087487","https://openalex.org/I4210110495"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Viktor Sip","raw_affiliation_strings":["Aix Marseille Univ, INSERM, INS, Inst Neurosci Syst, Marseille, France"],"raw_orcid":"https://orcid.org/0000-0002-5006-9765","affiliations":[{"raw_affiliation_string":"Aix Marseille Univ, INSERM, INS, Inst Neurosci Syst, Marseille, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210110495"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014488498","display_name":"Sandra Diaz-Pier","orcid":"https://orcid.org/0000-0002-3168-5394"},"institutions":[{"id":"https://openalex.org/I171892758","display_name":"Forschungszentrum J\u00fclich","ror":"https://ror.org/02nv7yv05","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I171892758"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Sandra Diaz-Pier","raw_affiliation_strings":["SimLab Neuroscience, J\u00fclich Supercomputing Centre (JSC), Institute for Advanced Simulation, JARA, Forschungszentrum J\u00fclich GmbH, J\u00fclich, Germany"],"raw_orcid":"https://orcid.org/0000-0002-3168-5394","affiliations":[{"raw_affiliation_string":"SimLab Neuroscience, J\u00fclich Supercomputing Centre (JSC), Institute for Advanced Simulation, JARA, Forschungszentrum J\u00fclich GmbH, J\u00fclich, Germany","institution_ids":["https://openalex.org/I171892758"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081751733","display_name":"Alexander Peyser","orcid":"https://orcid.org/0000-0002-3453-310X"},"institutions":[{"id":"https://openalex.org/I171892758","display_name":"Forschungszentrum J\u00fclich","ror":"https://ror.org/02nv7yv05","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I171892758"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Alexander Peyser","raw_affiliation_strings":["Google, M\u00fcnchen, Germany","SimLab Neuroscience, J\u00fclich Supercomputing Centre (JSC), Institute for Advanced Simulation, JARA, Forschungszentrum J\u00fclich GmbH, J\u00fclich, Germany"],"raw_orcid":"https://orcid.org/0000-0002-3453-310X","affiliations":[{"raw_affiliation_string":"Google, M\u00fcnchen, Germany","institution_ids":[]},{"raw_affiliation_string":"SimLab Neuroscience, J\u00fclich Supercomputing Centre (JSC), Institute for Advanced Simulation, JARA, Forschungszentrum J\u00fclich GmbH, J\u00fclich, Germany","institution_ids":["https://openalex.org/I171892758"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101446999","display_name":"Huifang Wang","orcid":"https://orcid.org/0000-0002-4060-8649"},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210110495","display_name":"Institut de Neurosciences des Syst\u00e8mes","ror":"https://ror.org/019kqby73","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I21491767","https://openalex.org/I4210087487","https://openalex.org/I4210110495"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Huifang Wang","raw_affiliation_strings":["Aix Marseille Univ, INSERM, INS, Inst Neurosci Syst, Marseille, France"],"raw_orcid":"https://orcid.org/0000-0002-4060-8649","affiliations":[{"raw_affiliation_string":"Aix Marseille Univ, INSERM, INS, Inst Neurosci Syst, Marseille, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210110495"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091400465","display_name":"Maxime Guye","orcid":"https://orcid.org/0000-0002-4435-2257"},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210140159","display_name":"Centre de R\u00e9sonance Magn\u00e9tique Biologique et M\u00e9dicale","ror":"https://ror.org/04ceg1205","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I1294671590","https://openalex.org/I21491767","https://openalex.org/I4210095849","https://openalex.org/I4210140159"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Maxime Guye","raw_affiliation_strings":["Aix Marseille Univ, CNRS, CRMBM, Marseille, France"],"raw_orcid":"https://orcid.org/0000-0002-4435-2257","affiliations":[{"raw_affiliation_string":"Aix Marseille Univ, CNRS, CRMBM, Marseille, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210140159"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090764517","display_name":"Fabrice Bartolom\u00e9i","orcid":"https://orcid.org/0000-0002-1678-0297"},"institutions":[{"id":"https://openalex.org/I4210087487","display_name":"Assistance Publique H\u00f4pitaux de Marseille","ror":"https://ror.org/002cp4060","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210087487"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Fabrice Bartolomei","raw_affiliation_strings":["Epileptology Department, and Clinical Neurophysiology Department, Assistance Publique des H\u00f4pitaux de Marseille, Marseille, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Epileptology Department, and Clinical Neurophysiology Department, Assistance Publique des H\u00f4pitaux de Marseille, Marseille, France","institution_ids":["https://openalex.org/I4210087487"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089030889","display_name":"Marmaduke Woodman","orcid":"https://orcid.org/0000-0002-8410-4581"},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210110495","display_name":"Institut de Neurosciences des Syst\u00e8mes","ror":"https://ror.org/019kqby73","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I21491767","https://openalex.org/I4210087487","https://openalex.org/I4210110495"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Marmaduke M. Woodman","raw_affiliation_strings":["Aix Marseille Univ, INSERM, INS, Inst Neurosci Syst, Marseille, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Aix Marseille Univ, INSERM, INS, Inst Neurosci Syst, Marseille, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210110495"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5047727568","display_name":"Viktor Jirsa","orcid":"https://orcid.org/0000-0002-8251-8860"},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210110495","display_name":"Institut de Neurosciences des Syst\u00e8mes","ror":"https://ror.org/019kqby73","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I21491767","https://openalex.org/I4210087487","https://openalex.org/I4210110495"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Viktor K. Jirsa","raw_affiliation_strings":["Aix Marseille Univ, INSERM, INS, Inst Neurosci Syst, Marseille, France"],"raw_orcid":"https://orcid.org/0000-0002-8251-8860","affiliations":[{"raw_affiliation_string":"Aix Marseille Univ, INSERM, INS, Inst Neurosci Syst, Marseille, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210110495"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5047727568","https://openalex.org/A5089498751"],"corresponding_institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210110495"],"apc_list":{"value":2655,"currency":"USD","value_usd":2655},"apc_paid":{"value":2655,"currency":"USD","value_usd":2655},"fwci":4.1094,"has_fulltext":true,"cited_by_count":49,"citation_normalized_percentile":{"value":0.95075802,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":100},"biblio":{"volume":"17","issue":"7","first_page":"e1009129","last_page":"e1009129"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11304","display_name":"Advanced Neuroimaging Techniques and Applications","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.9919000267982483,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/prior-probability","display_name":"Prior probability","score":0.8258708715438843},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6984561681747437},{"id":"https://openalex.org/keywords/bayesian-probability","display_name":"Bayesian probability","score":0.6683897972106934},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.574116587638855},{"id":"https://openalex.org/keywords/inference","display_name":"Inference","score":0.535525918006897},{"id":"https://openalex.org/keywords/bayesian-inference","display_name":"Bayesian inference","score":0.5199505090713501},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.5087159276008606}],"concepts":[{"id":"https://openalex.org/C177769412","wikidata":"https://www.wikidata.org/wiki/Q278090","display_name":"Prior probability","level":3,"score":0.8258708715438843},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6984561681747437},{"id":"https://openalex.org/C107673813","wikidata":"https://www.wikidata.org/wiki/Q812534","display_name":"Bayesian probability","level":2,"score":0.6683897972106934},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.574116587638855},{"id":"https://openalex.org/C2776214188","wikidata":"https://www.wikidata.org/wiki/Q408386","display_name":"Inference","level":2,"score":0.535525918006897},{"id":"https://openalex.org/C160234255","wikidata":"https://www.wikidata.org/wiki/Q812535","display_name":"Bayesian inference","level":3,"score":0.5199505090713501},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.5087159276008606}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001499","descriptor_name":"Bayes Theorem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001499","descriptor_name":"Bayes Theorem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001499","descriptor_name":"Bayes Theorem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001499","descriptor_name":"Bayes Theorem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D004827","descriptor_name":"Epilepsy","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D004827","descriptor_name":"Epilepsy","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D004827","descriptor_name":"Epilepsy","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D004827","descriptor_name":"Epilepsy","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D004827","descriptor_name":"Epilepsy","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D004827","descriptor_name":"Epilepsy","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D004827","descriptor_name":"Epilepsy","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D004827","descriptor_name":"Epilepsy","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D004827","descriptor_name":"Epilepsy","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D004827","descriptor_name":"Epilepsy","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D004827","descriptor_name":"Epilepsy","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D004827","descriptor_name":"Epilepsy","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D004827","descriptor_name":"Epilepsy","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D004827","descriptor_name":"Epilepsy","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D004827","descriptor_name":"Epilepsy","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D004827","descriptor_name":"Epilepsy","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1371/journal.pcbi.1009129","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1009129","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1009129&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},{"id":"pmid:34260596","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34260596","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS computational biology","raw_type":null},{"id":"pmh:oai:HAL:hal-03310886v1","is_oa":true,"landing_page_url":"https://hal.science/hal-03310886","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL (Le Centre pour la Communication Scientifique Directe)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1294671590","host_organization_name":"Centre National de la Recherche Scientifique","host_organization_lineage":["https://openalex.org/I1294671590"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Computational Biology, 2021, 17 (7), pp.e1009129. ⟨10.1371/journal.pcbi.1009129⟩","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:RePEc:plo:pcbi00:1009129","is_oa":false,"landing_page_url":"https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1009129","pdf_url":null,"source":{"id":"https://openalex.org/S4306401271","display_name":"RePEc: Research Papers in Economics","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I77793887","host_organization_name":"Federal Reserve Bank of St. Louis","host_organization_lineage":["https://openalex.org/I77793887"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"},{"id":"pmh:oai:doaj.org/article:f18937fa6a4141e2811371d370af1a29","is_oa":true,"landing_page_url":"https://doaj.org/article/f18937fa6a4141e2811371d370af1a29","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Computational Biology, Vol 17, Iss 7, p e1009129 (2021)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:8312957","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8312957","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Comput Biol","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1371/journal.pcbi.1009129","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1009129","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1009129&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/4","score":0.44999998807907104,"display_name":"Quality Education"}],"awards":[{"id":"https://openalex.org/G204998015","display_name":"Personalized Recommendations for Neurodegenerative Disease","funder_award_id":"826421","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G3230416436","display_name":null,"funder_award_id":"785907","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"},{"id":"https://openalex.org/G434337789","display_name":null,"funder_award_id":"HORIZON2020","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G4530127105","display_name":null,"funder_award_id":"945539","funder_id":"https://openalex.org/F4320332999","funder_display_name":"Horizon 2020 Framework Programme"},{"id":"https://openalex.org/G4877063124","display_name":null,"funder_award_id":"827-SA-16-UAM","funder_id":"https://openalex.org/F7870308689","funder_display_name":"SATT Sud-Est"},{"id":"https://openalex.org/G5303564930","display_name":null,"funder_award_id":"826421","funder_id":"https://openalex.org/F4320332999","funder_display_name":"Horizon 2020 Framework Programme"},{"id":"https://openalex.org/G5349343176","display_name":null,"funder_award_id":"DIC20161236442","funder_id":"https://openalex.org/F4320327841","funder_display_name":"Fondation G\u00e9n\u00e9rale de Sant\u00e9"},{"id":"https://openalex.org/G5746928057","display_name":null,"funder_award_id":"945539","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"},{"id":"https://openalex.org/G5766349579","display_name":"Human Brain Project Specific Grant Agreement 2","funder_award_id":"785907","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G6607577419","display_name":null,"funder_award_id":"785907","funder_id":"https://openalex.org/F4320332999","funder_display_name":"Horizon 2020 Framework Programme"},{"id":"https://openalex.org/G6803667113","display_name":null,"funder_award_id":"ANR-17","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"},{"id":"https://openalex.org/G8558765157","display_name":null,"funder_award_id":"785907 and 945539","funder_id":"https://openalex.org/F4320332999","funder_display_name":"Horizon 2020 Framework Programme"},{"id":"https://openalex.org/G8628712415","display_name":"Improving EPilepsy surgery management and progNOsis using Virtual brain technology","funder_award_id":"ANR-17-RHUS-0004","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"},{"id":"https://openalex.org/G8767435255","display_name":"Human Brain Project Specific Grant Agreement 3","funder_award_id":"945539","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"}],"funders":[{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320320883","display_name":"Agence Nationale de la Recherche","ror":"https://ror.org/00rbzpz17"},{"id":"https://openalex.org/F4320327841","display_name":"Fondation G\u00e9n\u00e9rale de Sant\u00e9","ror":null},{"id":"https://openalex.org/F4320330625","display_name":"Soci\u00e9t\u00e9 d'Acc\u00e9l\u00e9ration du Transfert de Technologies","ror":null},{"id":"https://openalex.org/F4320332999","display_name":"Horizon 2020 Framework Programme","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320338463","display_name":"CHIST-ERA","ror":"https://ror.org/00rbzpz17"},{"id":"https://openalex.org/F7870308689","display_name":"SATT Sud-Est","ror":null}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3181378126.pdf","grobid_xml":"https://content.openalex.org/works/W3181378126.grobid-xml"},"referenced_works_count":116,"referenced_works":["https://openalex.org/W55848811","https://openalex.org/W826555121","https://openalex.org/W1003962816","https://openalex.org/W1496599205","https://openalex.org/W1598813349","https://openalex.org/W1603903339","https://openalex.org/W1723619723","https://openalex.org/W1853291804","https://openalex.org/W1857053476","https://openalex.org/W1877880381","https://openalex.org/W1967396577","https://openalex.org/W1968187292","https://openalex.org/W1968371014","https://openalex.org/W1974105735","https://openalex.org/W1979416967","https://openalex.org/W1987594947","https://openalex.org/W1997307080","https://openalex.org/W2001611992","https://openalex.org/W2009435671","https://openalex.org/W2013399084","https://openalex.org/W2032616735","https://openalex.org/W2035279803","https://openalex.org/W2043976332","https://openalex.org/W2044278781","https://openalex.org/W2044487285","https://openalex.org/W2049657715","https://openalex.org/W2052394872","https://openalex.org/W2052644075","https://openalex.org/W2059448777","https://openalex.org/W2074725578","https://openalex.org/W2076243793","https://openalex.org/W2087263274","https://openalex.org/W2093223772","https://openalex.org/W2096705406","https://openalex.org/W2100314517","https://openalex.org/W2101135654","https://openalex.org/W2108868276","https://openalex.org/W2111051773","https://openalex.org/W2116416291","https://openalex.org/W2116647777","https://openalex.org/W2117663940","https://openalex.org/W2117882336","https://openalex.org/W2118064230","https://openalex.org/W2123222757","https://openalex.org/W2129728285","https://openalex.org/W2130902307","https://openalex.org/W2139037554","https://openalex.org/W2142635246","https://openalex.org/W2145749918","https://openalex.org/W2146125629","https://openalex.org/W2148534890","https://openalex.org/W2150847325","https://openalex.org/W2158196600","https://openalex.org/W2161460637","https://openalex.org/W2165020904","https://openalex.org/W2166510873","https://openalex.org/W2168175751","https://openalex.org/W2169705862","https://openalex.org/W2203714058","https://openalex.org/W2217402295","https://openalex.org/W2272101450","https://openalex.org/W2279857902","https://openalex.org/W2310684638","https://openalex.org/W2339621375","https://openalex.org/W2414323848","https://openalex.org/W2473219140","https://openalex.org/W2483809583","https://openalex.org/W2503693433","https://openalex.org/W2529160738","https://openalex.org/W2539792571","https://openalex.org/W2572702041","https://openalex.org/W2577455646","https://openalex.org/W2577537660","https://openalex.org/W2614978180","https://openalex.org/W2622514185","https://openalex.org/W2728707994","https://openalex.org/W2728900082","https://openalex.org/W2738162199","https://openalex.org/W2773567857","https://openalex.org/W2786890178","https://openalex.org/W2791233421","https://openalex.org/W2792275927","https://openalex.org/W2795327628","https://openalex.org/W2797692459","https://openalex.org/W2808618339","https://openalex.org/W2888598199","https://openalex.org/W2897613819","https://openalex.org/W2901943374","https://openalex.org/W2911583375","https://openalex.org/W2911856924","https://openalex.org/W2916138623","https://openalex.org/W2921051283","https://openalex.org/W2950603596","https://openalex.org/W2954040150","https://openalex.org/W2955067947","https://openalex.org/W2962727772","https://openalex.org/W2963758424","https://openalex.org/W2963977107","https://openalex.org/W2968092170","https://openalex.org/W2976670629","https://openalex.org/W2995557786","https://openalex.org/W3023066206","https://openalex.org/W3033642508","https://openalex.org/W3044586123","https://openalex.org/W3101886251","https://openalex.org/W3105032258","https://openalex.org/W3105664040","https://openalex.org/W3123421154","https://openalex.org/W4211177544","https://openalex.org/W4213156773","https://openalex.org/W4235770099","https://openalex.org/W4241074797","https://openalex.org/W4247690662","https://openalex.org/W4386373863","https://openalex.org/W6742050601","https://openalex.org/W6760353796"],"related_works":["https://openalex.org/W2562263695","https://openalex.org/W2135187896","https://openalex.org/W2015518264","https://openalex.org/W2147201983","https://openalex.org/W2795035211","https://openalex.org/W2160108762","https://openalex.org/W2164129707","https://openalex.org/W4292122269","https://openalex.org/W2949366006","https://openalex.org/W2372267530"],"abstract_inverted_index":{"Individualized":[0],"anatomical":[1],"information":[2,24,40,49,154],"has":[3],"been":[4],"used":[5,102,199],"as":[6],"prior":[7],"knowledge":[8,66],"in":[9,25,200,211],"Bayesian":[10,39,72,174,195],"inference":[11],"paradigms":[12],"of":[13,37,58,83,86,91,108,123,135,141,165,186,216],"whole-brain":[14,187],"network":[15,214],"models.":[16],"However,":[17],"the":[18,35,47,56,81,105,119,124,139,153,163,172],"actual":[19],"sensitivity":[20],"to":[21,50,103,158,218],"such":[22],"personalized":[23],"priors":[26,129],"is":[27,101],"still":[28],"unknown.":[29],"In":[30,147],"this":[31,201],"study,":[32],"we":[33],"introduce":[34],"use":[36],"fully":[38,173,194],"criteria":[41,155,175],"and":[42,94,132,183],"leave-one-out":[43],"cross-validation":[44],"technique":[45],"on":[46,63,80],"subject-specific":[48],"assess":[51,177],"different":[52,111,144,178],"epileptogenicity":[53,109,142,164,208],"hypotheses":[54,137,179],"regarding":[55,138],"location":[57],"pathological":[59],"brain":[60,112,145,166,213],"areas":[61],"based":[62,197],"a":[64,88,95,204],"priori":[65],"from":[67],"dynamical":[68],"system":[69],"properties.":[70],"The":[71,193],"Virtual":[73],"Epileptic":[74],"Patient":[75],"(BVEP)":[76],"model,":[77],"which":[78],"relies":[79],"fusion":[82],"structural":[84,182],"data":[85],"individuals,":[87],"generative":[89,212],"model":[90,126],"epileptiform":[92],"discharges,":[93],"self-tuning":[96],"Monte":[97],"Carlo":[98],"sampling":[99],"algorithm,":[100],"infer":[104],"spatial":[106],"map":[107],"across":[110,143,191],"areas.":[113,167],"Our":[114],"results":[115],"indicate":[116],"that":[117,171,189],"measuring":[118],"out-of-sample":[120],"prediction":[121],"accuracy":[122],"BVEP":[125],"with":[127],"informative":[128],"enables":[130],"reliable":[131],"efficient":[133],"evaluation":[134],"potential":[136],"degree":[140],"regions.":[146],"contrast,":[148],"while":[149],"using":[150],"uninformative":[151],"priors,":[152],"are":[156],"unable":[157],"provide":[159],"strong":[160],"evidence":[161],"about":[162,180],"We":[168],"also":[169],"show":[170],"correctly":[176],"both":[181],"functional":[184],"components":[185],"models":[188,215],"differ":[190],"individuals.":[192],"information-theory":[196],"approach":[198],"study":[202],"suggests":[203],"patient-specific":[205],"strategy":[206],"for":[207],"hypothesis":[209],"testing":[210],"epilepsy":[217],"improve":[219],"surgical":[220],"outcomes.":[221]},"counts_by_year":[{"year":2025,"cited_by_count":10},{"year":2024,"cited_by_count":16},{"year":2023,"cited_by_count":12},{"year":2022,"cited_by_count":10},{"year":2021,"cited_by_count":1}],"updated_date":"2026-08-06T08:24:18.245995","created_date":"2025-10-10T00:00:00"}