{"id":"https://openalex.org/W3137515854","doi":"https://doi.org/10.1371/journal.pcbi.1008785","title":"SARS-CoV-2 viral dynamics in non-human primates","display_name":"SARS-CoV-2 viral dynamics in non-human primates","publication_year":2021,"publication_date":"2021-03-17","ids":{"openalex":"https://openalex.org/W3137515854","doi":"https://doi.org/10.1371/journal.pcbi.1008785","mag":"3137515854","pmid":"https://pubmed.ncbi.nlm.nih.gov/33730053"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pcbi.1008785","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1008785","pdf_url":null,"source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1371/journal.pcbi.1008785","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5003970120","display_name":"Ant\u00f3nio Gon\u00e7alves","orcid":"https://orcid.org/0000-0002-8759-2429"},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I204730241","display_name":"Universit\u00e9 Paris Cit\u00e9","ror":"https://ror.org/05f82e368","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Antonio Gon\u00e7alves","raw_affiliation_strings":["Universit\u00e9 de Paris, IAME, INSERM, Paris, France"],"affiliations":[{"raw_affiliation_string":"Universit\u00e9 de Paris, IAME, INSERM, Paris, France","institution_ids":["https://openalex.org/I204730241","https://openalex.org/I154526488"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071955276","display_name":"Pauline Maisonnasse","orcid":"https://orcid.org/0000-0002-0555-207X"},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I2738703131","display_name":"Commissariat \u00e0 l'\u00c9nergie Atomique et aux \u00c9nergies Alternatives","ror":"https://ror.org/00jjx8s55","country_code":"FR","type":"government","lineage":["https://openalex.org/I2738703131"]},{"id":"https://openalex.org/I277688954","display_name":"Universit\u00e9 Paris-Saclay","ror":"https://ror.org/03xjwb503","country_code":"FR","type":"education","lineage":["https://openalex.org/I277688954"]},{"id":"https://openalex.org/I4210128565","display_name":"CEA Paris-Saclay","ror":"https://ror.org/03n15ch10","country_code":"FR","type":"government","lineage":["https://openalex.org/I2738703131","https://openalex.org/I277688954","https://openalex.org/I4210128565"]},{"id":"https://openalex.org/I4210128767","display_name":"Infectious Disease Models and Innovative Therapies","ror":"https://ror.org/03bk36k19","country_code":"FR","type":"facility","lineage":["https://openalex.org/I4210128767"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Pauline Maisonnasse","raw_affiliation_strings":["Universit\u00e9 Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT), Fontenay-aux-Roses & Le Kremlin-Bic\u00eatre, France"],"affiliations":[{"raw_affiliation_string":"Universit\u00e9 Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT), Fontenay-aux-Roses & Le Kremlin-Bic\u00eatre, France","institution_ids":["https://openalex.org/I4210128767","https://openalex.org/I154526488","https://openalex.org/I277688954","https://openalex.org/I4210128565","https://openalex.org/I2738703131"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058755701","display_name":"Flora Donati","orcid":"https://orcid.org/0000-0003-2862-9751"},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I157536573","display_name":"Institut Pasteur","ror":"https://ror.org/0495fxg12","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I157536573"]},{"id":"https://openalex.org/I204730241","display_name":"Universit\u00e9 Paris Cit\u00e9","ror":"https://ror.org/05f82e368","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Flora Donati","raw_affiliation_strings":["Centre National de R\u00e9f\u00e9rence des Virus des infections respiratoires (dont la grippe), Institut Pasteur, Paris, France","Unit\u00e9 de G\u00e9n\u00e9tique Mol\u00e9culaire des Virus \u00e0 ARN, GMVR: Institut Pasteur, UMR CNRS 3569, Universit\u00e9 de Paris, Paris, France"],"affiliations":[{"raw_affiliation_string":"Centre National de R\u00e9f\u00e9rence des Virus des infections respiratoires (dont la grippe), Institut Pasteur, Paris, France","institution_ids":["https://openalex.org/I157536573"]},{"raw_affiliation_string":"Unit\u00e9 de G\u00e9n\u00e9tique Mol\u00e9culaire des Virus \u00e0 ARN, GMVR: Institut Pasteur, UMR CNRS 3569, Universit\u00e9 de Paris, Paris, France","institution_ids":["https://openalex.org/I157536573","https://openalex.org/I204730241","https://openalex.org/I1294671590"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068111321","display_name":"M\u00e9lanie Albert","orcid":"https://orcid.org/0000-0002-3826-8729"},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I157536573","display_name":"Institut Pasteur","ror":"https://ror.org/0495fxg12","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I157536573"]},{"id":"https://openalex.org/I204730241","display_name":"Universit\u00e9 Paris Cit\u00e9","ror":"https://ror.org/05f82e368","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"M\u00e9lanie Albert","raw_affiliation_strings":["Centre National de R\u00e9f\u00e9rence des Virus des infections respiratoires (dont la grippe), Institut Pasteur, Paris, France","Unit\u00e9 de G\u00e9n\u00e9tique Mol\u00e9culaire des Virus \u00e0 ARN, GMVR: Institut Pasteur, UMR CNRS 3569, Universit\u00e9 de Paris, Paris, France"],"affiliations":[{"raw_affiliation_string":"Centre National de R\u00e9f\u00e9rence des Virus des infections respiratoires (dont la grippe), Institut Pasteur, Paris, France","institution_ids":["https://openalex.org/I157536573"]},{"raw_affiliation_string":"Unit\u00e9 de G\u00e9n\u00e9tique Mol\u00e9culaire des Virus \u00e0 ARN, GMVR: Institut Pasteur, UMR CNRS 3569, Universit\u00e9 de Paris, Paris, France","institution_ids":["https://openalex.org/I157536573","https://openalex.org/I204730241","https://openalex.org/I1294671590"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037100913","display_name":"Sylvie Behillil","orcid":"https://orcid.org/0000-0002-1520-5020"},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I157536573","display_name":"Institut Pasteur","ror":"https://ror.org/0495fxg12","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I157536573"]},{"id":"https://openalex.org/I204730241","display_name":"Universit\u00e9 Paris Cit\u00e9","ror":"https://ror.org/05f82e368","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Sylvie Behillil","raw_affiliation_strings":["Centre National de R\u00e9f\u00e9rence des Virus des infections respiratoires (dont la grippe), Institut Pasteur, Paris, France","Unit\u00e9 de G\u00e9n\u00e9tique Mol\u00e9culaire des Virus \u00e0 ARN, GMVR: Institut Pasteur, UMR CNRS 3569, Universit\u00e9 de Paris, Paris, France"],"affiliations":[{"raw_affiliation_string":"Centre National de R\u00e9f\u00e9rence des Virus des infections respiratoires (dont la grippe), Institut Pasteur, Paris, France","institution_ids":["https://openalex.org/I157536573"]},{"raw_affiliation_string":"Unit\u00e9 de G\u00e9n\u00e9tique Mol\u00e9culaire des Virus \u00e0 ARN, GMVR: Institut Pasteur, UMR CNRS 3569, Universit\u00e9 de Paris, Paris, France","institution_ids":["https://openalex.org/I157536573","https://openalex.org/I204730241","https://openalex.org/I1294671590"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001340881","display_name":"Vanessa Contreras","orcid":"https://orcid.org/0000-0003-4072-9819"},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I2738703131","display_name":"Commissariat \u00e0 l'\u00c9nergie Atomique et aux \u00c9nergies Alternatives","ror":"https://ror.org/00jjx8s55","country_code":"FR","type":"government","lineage":["https://openalex.org/I2738703131"]},{"id":"https://openalex.org/I277688954","display_name":"Universit\u00e9 Paris-Saclay","ror":"https://ror.org/03xjwb503","country_code":"FR","type":"education","lineage":["https://openalex.org/I277688954"]},{"id":"https://openalex.org/I4210128565","display_name":"CEA Paris-Saclay","ror":"https://ror.org/03n15ch10","country_code":"FR","type":"government","lineage":["https://openalex.org/I2738703131","https://openalex.org/I277688954","https://openalex.org/I4210128565"]},{"id":"https://openalex.org/I4210128767","display_name":"Infectious Disease Models and Innovative Therapies","ror":"https://ror.org/03bk36k19","country_code":"FR","type":"facility","lineage":["https://openalex.org/I4210128767"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Vanessa Contreras","raw_affiliation_strings":["Universit\u00e9 Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT), Fontenay-aux-Roses & Le Kremlin-Bic\u00eatre, France"],"affiliations":[{"raw_affiliation_string":"Universit\u00e9 Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT), Fontenay-aux-Roses & Le Kremlin-Bic\u00eatre, France","institution_ids":["https://openalex.org/I4210128767","https://openalex.org/I154526488","https://openalex.org/I277688954","https://openalex.org/I4210128565","https://openalex.org/I2738703131"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052265701","display_name":"Thibaut Naninck","orcid":null},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I2738703131","display_name":"Commissariat \u00e0 l'\u00c9nergie Atomique et aux \u00c9nergies Alternatives","ror":"https://ror.org/00jjx8s55","country_code":"FR","type":"government","lineage":["https://openalex.org/I2738703131"]},{"id":"https://openalex.org/I277688954","display_name":"Universit\u00e9 Paris-Saclay","ror":"https://ror.org/03xjwb503","country_code":"FR","type":"education","lineage":["https://openalex.org/I277688954"]},{"id":"https://openalex.org/I4210128565","display_name":"CEA Paris-Saclay","ror":"https://ror.org/03n15ch10","country_code":"FR","type":"government","lineage":["https://openalex.org/I2738703131","https://openalex.org/I277688954","https://openalex.org/I4210128565"]},{"id":"https://openalex.org/I4210128767","display_name":"Infectious Disease Models and Innovative Therapies","ror":"https://ror.org/03bk36k19","country_code":"FR","type":"facility","lineage":["https://openalex.org/I4210128767"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Thibaut Naninck","raw_affiliation_strings":["Universit\u00e9 Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT), Fontenay-aux-Roses & Le Kremlin-Bic\u00eatre, France"],"affiliations":[{"raw_affiliation_string":"Universit\u00e9 Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT), Fontenay-aux-Roses & Le Kremlin-Bic\u00eatre, France","institution_ids":["https://openalex.org/I4210128767","https://openalex.org/I154526488","https://openalex.org/I277688954","https://openalex.org/I4210128565","https://openalex.org/I2738703131"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037631225","display_name":"Romain Marlin","orcid":"https://orcid.org/0000-0001-8932-0171"},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I2738703131","display_name":"Commissariat \u00e0 l'\u00c9nergie Atomique et aux \u00c9nergies Alternatives","ror":"https://ror.org/00jjx8s55","country_code":"FR","type":"government","lineage":["https://openalex.org/I2738703131"]},{"id":"https://openalex.org/I277688954","display_name":"Universit\u00e9 Paris-Saclay","ror":"https://ror.org/03xjwb503","country_code":"FR","type":"education","lineage":["https://openalex.org/I277688954"]},{"id":"https://openalex.org/I4210128565","display_name":"CEA Paris-Saclay","ror":"https://ror.org/03n15ch10","country_code":"FR","type":"government","lineage":["https://openalex.org/I2738703131","https://openalex.org/I277688954","https://openalex.org/I4210128565"]},{"id":"https://openalex.org/I4210128767","display_name":"Infectious Disease Models and Innovative Therapies","ror":"https://ror.org/03bk36k19","country_code":"FR","type":"facility","lineage":["https://openalex.org/I4210128767"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Romain Marlin","raw_affiliation_strings":["Universit\u00e9 Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT), Fontenay-aux-Roses & Le Kremlin-Bic\u00eatre, France"],"affiliations":[{"raw_affiliation_string":"Universit\u00e9 Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT), Fontenay-aux-Roses & Le Kremlin-Bic\u00eatre, France","institution_ids":["https://openalex.org/I4210128767","https://openalex.org/I154526488","https://openalex.org/I277688954","https://openalex.org/I4210128565","https://openalex.org/I2738703131"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045396101","display_name":"Caroline Solas","orcid":"https://orcid.org/0000-0002-0943-9648"},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210162909","display_name":"H\u00f4pital de la Timone","ror":"https://ror.org/05jrr4320","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210087487","https://openalex.org/I4210162909"]},{"id":"https://openalex.org/I4210166444","display_name":"Institut de Recherche pour le D\u00e9veloppement","ror":"https://ror.org/05q3vnk25","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590","https://openalex.org/I1327553481","https://openalex.org/I154202486","https://openalex.org/I2799535048","https://openalex.org/I2802818602","https://openalex.org/I4210088668","https://openalex.org/I4210090127","https://openalex.org/I4210113730","https://openalex.org/I4210131494","https://openalex.org/I4210166444","https://openalex.org/I4405257220"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Caroline Solas","raw_affiliation_strings":["Aix-Marseille Univ, APHM, Unit\u00e9 des Virus Emergents (UVE) IRD 190, INSERM 1207, Laboratoire de Pharmacocin\u00e9tique et Toxicologie, H\u00f4pital La Timone, Marseille, France"],"affiliations":[{"raw_affiliation_string":"Aix-Marseille Univ, APHM, Unit\u00e9 des Virus Emergents (UVE) IRD 190, INSERM 1207, Laboratoire de Pharmacocin\u00e9tique et Toxicologie, H\u00f4pital La Timone, Marseille, France","institution_ids":["https://openalex.org/I4210162909","https://openalex.org/I154526488","https://openalex.org/I4210166444"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089302623","display_name":"Andr\u00e9s Pizzorno","orcid":"https://orcid.org/0000-0002-0918-6804"},"institutions":[{"id":"https://openalex.org/I100532134","display_name":"Universit\u00e9 Claude Bernard Lyon 1","ror":"https://ror.org/029brtt94","country_code":"FR","type":"education","lineage":["https://openalex.org/I100532134","https://openalex.org/I203339264"]},{"id":"https://openalex.org/I113428412","display_name":"\u00c9cole Normale Sup\u00e9rieure de Lyon","ror":"https://ror.org/04zmssz18","country_code":"FR","type":"education","lineage":["https://openalex.org/I113428412","https://openalex.org/I203339264"]},{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210140403","display_name":"Virologie et Pathologies Humaines","ror":"https://ror.org/031xg0236","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I100532134","https://openalex.org/I113428412","https://openalex.org/I113428412","https://openalex.org/I1294671590","https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I154526488","https://openalex.org/I203339264","https://openalex.org/I203339264","https://openalex.org/I203339264","https://openalex.org/I203339264","https://openalex.org/I203339264","https://openalex.org/I4210089901","https://openalex.org/I4210100596","https://openalex.org/I4210100596","https://openalex.org/I4210139971","https://openalex.org/I4210140403","https://openalex.org/I4210155509","https://openalex.org/I4210161906","https://openalex.org/I4405259976"]},{"id":"https://openalex.org/I4210161906","display_name":"Centre International de Recherche en Infectiologie","ror":"https://ror.org/059sz6q14","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I113428412","https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I203339264","https://openalex.org/I203339264","https://openalex.org/I203339264","https://openalex.org/I4210100596","https://openalex.org/I4210161906","https://openalex.org/I4405259976"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Andres Pizzorno","raw_affiliation_strings":["CIRI, Centre International de Recherche en Infectiologie, (Team VirPath), Univ Lyon, Inserm, U1111, Universit\u00e9 Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France"],"affiliations":[{"raw_affiliation_string":"CIRI, Centre International de Recherche en Infectiologie, (Team VirPath), Univ Lyon, Inserm, U1111, Universit\u00e9 Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France","institution_ids":["https://openalex.org/I4210161906","https://openalex.org/I100532134","https://openalex.org/I4210140403","https://openalex.org/I154526488","https://openalex.org/I113428412","https://openalex.org/I1294671590"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050653467","display_name":"Julien Lema\u00eetre","orcid":"https://orcid.org/0000-0001-6239-0110"},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I2738703131","display_name":"Commissariat \u00e0 l'\u00c9nergie Atomique et aux \u00c9nergies Alternatives","ror":"https://ror.org/00jjx8s55","country_code":"FR","type":"government","lineage":["https://openalex.org/I2738703131"]},{"id":"https://openalex.org/I277688954","display_name":"Universit\u00e9 Paris-Saclay","ror":"https://ror.org/03xjwb503","country_code":"FR","type":"education","lineage":["https://openalex.org/I277688954"]},{"id":"https://openalex.org/I4210128565","display_name":"CEA Paris-Saclay","ror":"https://ror.org/03n15ch10","country_code":"FR","type":"government","lineage":["https://openalex.org/I2738703131","https://openalex.org/I277688954","https://openalex.org/I4210128565"]},{"id":"https://openalex.org/I4210128767","display_name":"Infectious Disease Models and Innovative Therapies","ror":"https://ror.org/03bk36k19","country_code":"FR","type":"facility","lineage":["https://openalex.org/I4210128767"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Julien Lemaitre","raw_affiliation_strings":["Universit\u00e9 Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT), Fontenay-aux-Roses & Le Kremlin-Bic\u00eatre, France"],"affiliations":[{"raw_affiliation_string":"Universit\u00e9 Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT), Fontenay-aux-Roses & Le Kremlin-Bic\u00eatre, France","institution_ids":["https://openalex.org/I4210128767","https://openalex.org/I154526488","https://openalex.org/I277688954","https://openalex.org/I4210128565","https://openalex.org/I2738703131"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010608795","display_name":"Nidhal Kahlaoui","orcid":"https://orcid.org/0000-0003-4784-0819"},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I2738703131","display_name":"Commissariat \u00e0 l'\u00c9nergie Atomique et aux \u00c9nergies Alternatives","ror":"https://ror.org/00jjx8s55","country_code":"FR","type":"government","lineage":["https://openalex.org/I2738703131"]},{"id":"https://openalex.org/I277688954","display_name":"Universit\u00e9 Paris-Saclay","ror":"https://ror.org/03xjwb503","country_code":"FR","type":"education","lineage":["https://openalex.org/I277688954"]},{"id":"https://openalex.org/I4210128565","display_name":"CEA Paris-Saclay","ror":"https://ror.org/03n15ch10","country_code":"FR","type":"government","lineage":["https://openalex.org/I2738703131","https://openalex.org/I277688954","https://openalex.org/I4210128565"]},{"id":"https://openalex.org/I4210128767","display_name":"Infectious Disease Models and Innovative Therapies","ror":"https://ror.org/03bk36k19","country_code":"FR","type":"facility","lineage":["https://openalex.org/I4210128767"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Nidhal Kahlaoui","raw_affiliation_strings":["Universit\u00e9 Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT), Fontenay-aux-Roses & Le Kremlin-Bic\u00eatre, France"],"affiliations":[{"raw_affiliation_string":"Universit\u00e9 Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT), Fontenay-aux-Roses & Le Kremlin-Bic\u00eatre, France","institution_ids":["https://openalex.org/I4210128767","https://openalex.org/I154526488","https://openalex.org/I277688954","https://openalex.org/I4210128565","https://openalex.org/I2738703131"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010707925","display_name":"Olivier Terrier","orcid":"https://orcid.org/0000-0001-9393-7684"},"institutions":[{"id":"https://openalex.org/I100532134","display_name":"Universit\u00e9 Claude Bernard Lyon 1","ror":"https://ror.org/029brtt94","country_code":"FR","type":"education","lineage":["https://openalex.org/I100532134","https://openalex.org/I203339264"]},{"id":"https://openalex.org/I113428412","display_name":"\u00c9cole Normale Sup\u00e9rieure de Lyon","ror":"https://ror.org/04zmssz18","country_code":"FR","type":"education","lineage":["https://openalex.org/I113428412","https://openalex.org/I203339264"]},{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210140403","display_name":"Virologie et Pathologies Humaines","ror":"https://ror.org/031xg0236","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I100532134","https://openalex.org/I113428412","https://openalex.org/I113428412","https://openalex.org/I1294671590","https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I154526488","https://openalex.org/I203339264","https://openalex.org/I203339264","https://openalex.org/I203339264","https://openalex.org/I203339264","https://openalex.org/I203339264","https://openalex.org/I4210089901","https://openalex.org/I4210100596","https://openalex.org/I4210100596","https://openalex.org/I4210139971","https://openalex.org/I4210140403","https://openalex.org/I4210155509","https://openalex.org/I4210161906","https://openalex.org/I4405259976"]},{"id":"https://openalex.org/I4210161906","display_name":"Centre International de Recherche en Infectiologie","ror":"https://ror.org/059sz6q14","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I113428412","https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I203339264","https://openalex.org/I203339264","https://openalex.org/I203339264","https://openalex.org/I4210100596","https://openalex.org/I4210161906","https://openalex.org/I4405259976"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Olivier Terrier","raw_affiliation_strings":["CIRI, Centre International de Recherche en Infectiologie, (Team VirPath), Univ Lyon, Inserm, U1111, Universit\u00e9 Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France"],"affiliations":[{"raw_affiliation_string":"CIRI, Centre International de Recherche en Infectiologie, (Team VirPath), Univ Lyon, Inserm, U1111, Universit\u00e9 Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France","institution_ids":["https://openalex.org/I4210161906","https://openalex.org/I100532134","https://openalex.org/I4210140403","https://openalex.org/I154526488","https://openalex.org/I113428412","https://openalex.org/I1294671590"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041869385","display_name":"Rapha\u00ebl Ho Tsong Fang","orcid":"https://orcid.org/0000-0002-2322-3392"},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I2738703131","display_name":"Commissariat \u00e0 l'\u00c9nergie Atomique et aux \u00c9nergies Alternatives","ror":"https://ror.org/00jjx8s55","country_code":"FR","type":"government","lineage":["https://openalex.org/I2738703131"]},{"id":"https://openalex.org/I277688954","display_name":"Universit\u00e9 Paris-Saclay","ror":"https://ror.org/03xjwb503","country_code":"FR","type":"education","lineage":["https://openalex.org/I277688954"]},{"id":"https://openalex.org/I4210128565","display_name":"CEA Paris-Saclay","ror":"https://ror.org/03n15ch10","country_code":"FR","type":"government","lineage":["https://openalex.org/I2738703131","https://openalex.org/I277688954","https://openalex.org/I4210128565"]},{"id":"https://openalex.org/I4210128767","display_name":"Infectious Disease Models and Innovative Therapies","ror":"https://ror.org/03bk36k19","country_code":"FR","type":"facility","lineage":["https://openalex.org/I4210128767"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Raphael Ho Tsong Fang","raw_affiliation_strings":["Universit\u00e9 Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT), Fontenay-aux-Roses & Le Kremlin-Bic\u00eatre, France"],"affiliations":[{"raw_affiliation_string":"Universit\u00e9 Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT), Fontenay-aux-Roses & Le Kremlin-Bic\u00eatre, France","institution_ids":["https://openalex.org/I4210128767","https://openalex.org/I154526488","https://openalex.org/I277688954","https://openalex.org/I4210128565","https://openalex.org/I2738703131"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041062231","display_name":"Vincent Enouf","orcid":"https://orcid.org/0000-0001-7609-4742"},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I157536573","display_name":"Institut Pasteur","ror":"https://ror.org/0495fxg12","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I157536573"]},{"id":"https://openalex.org/I204730241","display_name":"Universit\u00e9 Paris Cit\u00e9","ror":"https://ror.org/05f82e368","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Vincent Enouf","raw_affiliation_strings":["Centre National de R\u00e9f\u00e9rence des Virus des infections respiratoires (dont la grippe), Institut Pasteur, Paris, France","Plate-forme de microbiologie mutualis\u00e9e (P2M), Pasteur International Bioresources Network (PIBnet), Institut Pasteur, Paris, France","Unit\u00e9 de G\u00e9n\u00e9tique Mol\u00e9culaire des Virus \u00e0 ARN, GMVR: Institut Pasteur, UMR CNRS 3569, Universit\u00e9 de Paris, Paris, France"],"affiliations":[{"raw_affiliation_string":"Centre National de R\u00e9f\u00e9rence des Virus des infections respiratoires (dont la grippe), Institut Pasteur, Paris, France","institution_ids":["https://openalex.org/I157536573"]},{"raw_affiliation_string":"Plate-forme de microbiologie mutualis\u00e9e (P2M), Pasteur International Bioresources Network (PIBnet), Institut Pasteur, Paris, France","institution_ids":["https://openalex.org/I157536573"]},{"raw_affiliation_string":"Unit\u00e9 de G\u00e9n\u00e9tique Mol\u00e9culaire des Virus \u00e0 ARN, GMVR: Institut Pasteur, UMR CNRS 3569, Universit\u00e9 de Paris, Paris, France","institution_ids":["https://openalex.org/I157536573","https://openalex.org/I204730241","https://openalex.org/I1294671590"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007314757","display_name":"Nathalie Dereuddre\u2010Bosquet","orcid":"https://orcid.org/0000-0001-6682-6313"},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I2738703131","display_name":"Commissariat \u00e0 l'\u00c9nergie Atomique et aux \u00c9nergies Alternatives","ror":"https://ror.org/00jjx8s55","country_code":"FR","type":"government","lineage":["https://openalex.org/I2738703131"]},{"id":"https://openalex.org/I277688954","display_name":"Universit\u00e9 Paris-Saclay","ror":"https://ror.org/03xjwb503","country_code":"FR","type":"education","lineage":["https://openalex.org/I277688954"]},{"id":"https://openalex.org/I4210128565","display_name":"CEA Paris-Saclay","ror":"https://ror.org/03n15ch10","country_code":"FR","type":"government","lineage":["https://openalex.org/I2738703131","https://openalex.org/I277688954","https://openalex.org/I4210128565"]},{"id":"https://openalex.org/I4210128767","display_name":"Infectious Disease Models and Innovative Therapies","ror":"https://ror.org/03bk36k19","country_code":"FR","type":"facility","lineage":["https://openalex.org/I4210128767"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Nathalie Dereuddre-Bosquet","raw_affiliation_strings":["Universit\u00e9 Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT), Fontenay-aux-Roses & Le Kremlin-Bic\u00eatre, France"],"affiliations":[{"raw_affiliation_string":"Universit\u00e9 Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT), Fontenay-aux-Roses & Le Kremlin-Bic\u00eatre, France","institution_ids":["https://openalex.org/I4210128767","https://openalex.org/I154526488","https://openalex.org/I277688954","https://openalex.org/I4210128565","https://openalex.org/I2738703131"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085165494","display_name":"Angela Brisebarre","orcid":null},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I157536573","display_name":"Institut Pasteur","ror":"https://ror.org/0495fxg12","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I157536573"]},{"id":"https://openalex.org/I204730241","display_name":"Universit\u00e9 Paris Cit\u00e9","ror":"https://ror.org/05f82e368","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Angela Brisebarre","raw_affiliation_strings":["Centre National de R\u00e9f\u00e9rence des Virus des infections respiratoires (dont la grippe), Institut Pasteur, Paris, France","Unit\u00e9 de G\u00e9n\u00e9tique Mol\u00e9culaire des Virus \u00e0 ARN, GMVR: Institut Pasteur, UMR CNRS 3569, Universit\u00e9 de Paris, Paris, France"],"affiliations":[{"raw_affiliation_string":"Centre National de R\u00e9f\u00e9rence des Virus des infections respiratoires (dont la grippe), Institut Pasteur, Paris, France","institution_ids":["https://openalex.org/I157536573"]},{"raw_affiliation_string":"Unit\u00e9 de G\u00e9n\u00e9tique Mol\u00e9culaire des Virus \u00e0 ARN, GMVR: Institut Pasteur, UMR CNRS 3569, Universit\u00e9 de Paris, Paris, France","institution_ids":["https://openalex.org/I157536573","https://openalex.org/I204730241","https://openalex.org/I1294671590"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076994111","display_name":"Franck Touret","orcid":"https://orcid.org/0000-0002-4734-2249"},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210087217","display_name":"M\u00e9diterran\u00e9e Infection Foundation","ror":"https://ror.org/0068ff141","country_code":"FR","type":"other","lineage":["https://openalex.org/I4210087217"]},{"id":"https://openalex.org/I4210166444","display_name":"Institut de Recherche pour le D\u00e9veloppement","ror":"https://ror.org/05q3vnk25","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590","https://openalex.org/I1327553481","https://openalex.org/I154202486","https://openalex.org/I2799535048","https://openalex.org/I2802818602","https://openalex.org/I4210088668","https://openalex.org/I4210090127","https://openalex.org/I4210113730","https://openalex.org/I4210131494","https://openalex.org/I4210166444","https://openalex.org/I4405257220"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Franck Touret","raw_affiliation_strings":["Unit\u00e9 des Virus Emergents, UVE: Aix Marseille Univ, IRD 190, INSERM 1207, IHU M\u00e9diterran\u00e9e Infection, Marseille, France"],"affiliations":[{"raw_affiliation_string":"Unit\u00e9 des Virus Emergents, UVE: Aix Marseille Univ, IRD 190, INSERM 1207, IHU M\u00e9diterran\u00e9e Infection, Marseille, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210087217","https://openalex.org/I4210166444"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068681629","display_name":"Catherine Chapon","orcid":"https://orcid.org/0000-0002-3210-8468"},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I2738703131","display_name":"Commissariat \u00e0 l'\u00c9nergie Atomique et aux \u00c9nergies Alternatives","ror":"https://ror.org/00jjx8s55","country_code":"FR","type":"government","lineage":["https://openalex.org/I2738703131"]},{"id":"https://openalex.org/I277688954","display_name":"Universit\u00e9 Paris-Saclay","ror":"https://ror.org/03xjwb503","country_code":"FR","type":"education","lineage":["https://openalex.org/I277688954"]},{"id":"https://openalex.org/I4210128565","display_name":"CEA Paris-Saclay","ror":"https://ror.org/03n15ch10","country_code":"FR","type":"government","lineage":["https://openalex.org/I2738703131","https://openalex.org/I277688954","https://openalex.org/I4210128565"]},{"id":"https://openalex.org/I4210128767","display_name":"Infectious Disease Models and Innovative Therapies","ror":"https://ror.org/03bk36k19","country_code":"FR","type":"facility","lineage":["https://openalex.org/I4210128767"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Catherine Chapon","raw_affiliation_strings":["Universit\u00e9 Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT), Fontenay-aux-Roses & Le Kremlin-Bic\u00eatre, France"],"affiliations":[{"raw_affiliation_string":"Universit\u00e9 Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT), Fontenay-aux-Roses & Le Kremlin-Bic\u00eatre, France","institution_ids":["https://openalex.org/I4210128767","https://openalex.org/I154526488","https://openalex.org/I277688954","https://openalex.org/I4210128565","https://openalex.org/I2738703131"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002721139","display_name":"Bruno Hoen","orcid":"https://orcid.org/0000-0003-3070-3017"},"institutions":[{"id":"https://openalex.org/I157536573","display_name":"Institut Pasteur","ror":"https://ror.org/0495fxg12","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I157536573"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Bruno Hoen","raw_affiliation_strings":["Emerging Diseases Epidemiology Unit, Institut Pasteur, Paris, France"],"affiliations":[{"raw_affiliation_string":"Emerging Diseases Epidemiology Unit, Institut Pasteur, Paris, France","institution_ids":["https://openalex.org/I157536573"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043361043","display_name":"Bruno Lina","orcid":"https://orcid.org/0000-0002-8959-2123"},"institutions":[{"id":"https://openalex.org/I100532134","display_name":"Universit\u00e9 Claude Bernard Lyon 1","ror":"https://ror.org/029brtt94","country_code":"FR","type":"education","lineage":["https://openalex.org/I100532134","https://openalex.org/I203339264"]},{"id":"https://openalex.org/I113428412","display_name":"\u00c9cole Normale Sup\u00e9rieure de Lyon","ror":"https://ror.org/04zmssz18","country_code":"FR","type":"education","lineage":["https://openalex.org/I113428412","https://openalex.org/I203339264"]},{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210100596","display_name":"Hospices Civils de Lyon","ror":"https://ror.org/01502ca60","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210100596"]},{"id":"https://openalex.org/I4210140403","display_name":"Virologie et Pathologies Humaines","ror":"https://ror.org/031xg0236","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I100532134","https://openalex.org/I113428412","https://openalex.org/I113428412","https://openalex.org/I1294671590","https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I154526488","https://openalex.org/I203339264","https://openalex.org/I203339264","https://openalex.org/I203339264","https://openalex.org/I203339264","https://openalex.org/I203339264","https://openalex.org/I4210089901","https://openalex.org/I4210100596","https://openalex.org/I4210100596","https://openalex.org/I4210139971","https://openalex.org/I4210140403","https://openalex.org/I4210155509","https://openalex.org/I4210161906","https://openalex.org/I4405259976"]},{"id":"https://openalex.org/I4210161906","display_name":"Centre International de Recherche en Infectiologie","ror":"https://ror.org/059sz6q14","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I113428412","https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I203339264","https://openalex.org/I203339264","https://openalex.org/I203339264","https://openalex.org/I4210100596","https://openalex.org/I4210161906","https://openalex.org/I4405259976"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Bruno Lina","raw_affiliation_strings":["CIRI, Centre International de Recherche en Infectiologie, (Team VirPath), Univ Lyon, Inserm, U1111, Universit\u00e9 Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France","Laboratoire de Virologie, Centre National de R\u00e9f\u00e9rence des Virus des infections respiratoires (dont la grippe), Institut des Agents Infectieux, Groupement Hospitalier Nord, Hospices Civils de Lyon, Lyon, France"],"affiliations":[{"raw_affiliation_string":"CIRI, Centre International de Recherche en Infectiologie, (Team VirPath), Univ Lyon, Inserm, U1111, Universit\u00e9 Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France","institution_ids":["https://openalex.org/I4210161906","https://openalex.org/I100532134","https://openalex.org/I4210140403","https://openalex.org/I154526488","https://openalex.org/I113428412","https://openalex.org/I1294671590"]},{"raw_affiliation_string":"Laboratoire de Virologie, Centre National de R\u00e9f\u00e9rence des Virus des infections respiratoires (dont la grippe), Institut des Agents Infectieux, Groupement Hospitalier Nord, Hospices Civils de Lyon, Lyon, France","institution_ids":["https://openalex.org/I4210100596"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042500741","display_name":"Manuel Rosa\u2010Calatrava","orcid":"https://orcid.org/0000-0002-7559-9527"},"institutions":[{"id":"https://openalex.org/I100532134","display_name":"Universit\u00e9 Claude Bernard Lyon 1","ror":"https://ror.org/029brtt94","country_code":"FR","type":"education","lineage":["https://openalex.org/I100532134","https://openalex.org/I203339264"]},{"id":"https://openalex.org/I113428412","display_name":"\u00c9cole Normale Sup\u00e9rieure de Lyon","ror":"https://ror.org/04zmssz18","country_code":"FR","type":"education","lineage":["https://openalex.org/I113428412","https://openalex.org/I203339264"]},{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210140403","display_name":"Virologie et Pathologies Humaines","ror":"https://ror.org/031xg0236","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I100532134","https://openalex.org/I113428412","https://openalex.org/I113428412","https://openalex.org/I1294671590","https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I154526488","https://openalex.org/I203339264","https://openalex.org/I203339264","https://openalex.org/I203339264","https://openalex.org/I203339264","https://openalex.org/I203339264","https://openalex.org/I4210089901","https://openalex.org/I4210100596","https://openalex.org/I4210100596","https://openalex.org/I4210139971","https://openalex.org/I4210140403","https://openalex.org/I4210155509","https://openalex.org/I4210161906","https://openalex.org/I4405259976"]},{"id":"https://openalex.org/I4210161906","display_name":"Centre International de Recherche en Infectiologie","ror":"https://ror.org/059sz6q14","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I113428412","https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I203339264","https://openalex.org/I203339264","https://openalex.org/I203339264","https://openalex.org/I4210100596","https://openalex.org/I4210161906","https://openalex.org/I4405259976"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Manuel Rosa Calatrava","raw_affiliation_strings":["CIRI, Centre International de Recherche en Infectiologie, (Team VirPath), Univ Lyon, Inserm, U1111, Universit\u00e9 Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France"],"affiliations":[{"raw_affiliation_string":"CIRI, Centre International de Recherche en Infectiologie, (Team VirPath), Univ Lyon, Inserm, U1111, Universit\u00e9 Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France","institution_ids":["https://openalex.org/I4210161906","https://openalex.org/I100532134","https://openalex.org/I4210140403","https://openalex.org/I154526488","https://openalex.org/I113428412","https://openalex.org/I1294671590"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067395185","display_name":"Xavier de Lamballerie","orcid":"https://orcid.org/0000-0001-7895-2720"},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210087217","display_name":"M\u00e9diterran\u00e9e Infection Foundation","ror":"https://ror.org/0068ff141","country_code":"FR","type":"other","lineage":["https://openalex.org/I4210087217"]},{"id":"https://openalex.org/I4210166444","display_name":"Institut de Recherche pour le D\u00e9veloppement","ror":"https://ror.org/05q3vnk25","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590","https://openalex.org/I1327553481","https://openalex.org/I154202486","https://openalex.org/I2799535048","https://openalex.org/I2802818602","https://openalex.org/I4210088668","https://openalex.org/I4210090127","https://openalex.org/I4210113730","https://openalex.org/I4210131494","https://openalex.org/I4210166444","https://openalex.org/I4405257220"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Xavier de Lamballerie","raw_affiliation_strings":["Unit\u00e9 des Virus Emergents, UVE: Aix Marseille Univ, IRD 190, INSERM 1207, IHU M\u00e9diterran\u00e9e Infection, Marseille, France"],"affiliations":[{"raw_affiliation_string":"Unit\u00e9 des Virus Emergents, UVE: Aix Marseille Univ, IRD 190, INSERM 1207, IHU M\u00e9diterran\u00e9e Infection, Marseille, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210087217","https://openalex.org/I4210166444"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031224690","display_name":"France Mentr\u00e9","orcid":"https://orcid.org/0000-0002-7045-1275"},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I204730241","display_name":"Universit\u00e9 Paris Cit\u00e9","ror":"https://ror.org/05f82e368","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"France Mentr\u00e9","raw_affiliation_strings":["Universit\u00e9 de Paris, IAME, INSERM, Paris, France"],"affiliations":[{"raw_affiliation_string":"Universit\u00e9 de Paris, IAME, INSERM, Paris, France","institution_ids":["https://openalex.org/I204730241","https://openalex.org/I154526488"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032170909","display_name":"Roger Le Grand","orcid":"https://orcid.org/0000-0002-4928-4484"},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I2738703131","display_name":"Commissariat \u00e0 l'\u00c9nergie Atomique et aux \u00c9nergies Alternatives","ror":"https://ror.org/00jjx8s55","country_code":"FR","type":"government","lineage":["https://openalex.org/I2738703131"]},{"id":"https://openalex.org/I277688954","display_name":"Universit\u00e9 Paris-Saclay","ror":"https://ror.org/03xjwb503","country_code":"FR","type":"education","lineage":["https://openalex.org/I277688954"]},{"id":"https://openalex.org/I4210128565","display_name":"CEA Paris-Saclay","ror":"https://ror.org/03n15ch10","country_code":"FR","type":"government","lineage":["https://openalex.org/I2738703131","https://openalex.org/I277688954","https://openalex.org/I4210128565"]},{"id":"https://openalex.org/I4210128767","display_name":"Infectious Disease Models and Innovative Therapies","ror":"https://ror.org/03bk36k19","country_code":"FR","type":"facility","lineage":["https://openalex.org/I4210128767"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Roger Le Grand","raw_affiliation_strings":["Universit\u00e9 Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT), Fontenay-aux-Roses & Le Kremlin-Bic\u00eatre, France"],"affiliations":[{"raw_affiliation_string":"Universit\u00e9 Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT), Fontenay-aux-Roses & Le Kremlin-Bic\u00eatre, France","institution_ids":["https://openalex.org/I4210128767","https://openalex.org/I154526488","https://openalex.org/I277688954","https://openalex.org/I4210128565","https://openalex.org/I2738703131"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000235818","display_name":"Sylvie van der Werf","orcid":"https://orcid.org/0000-0002-1148-4456"},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I157536573","display_name":"Institut Pasteur","ror":"https://ror.org/0495fxg12","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I157536573"]},{"id":"https://openalex.org/I204730241","display_name":"Universit\u00e9 Paris Cit\u00e9","ror":"https://ror.org/05f82e368","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Sylvie van der Werf","raw_affiliation_strings":["Centre National de R\u00e9f\u00e9rence des Virus des infections respiratoires (dont la grippe), Institut Pasteur, Paris, France","Unit\u00e9 de G\u00e9n\u00e9tique Mol\u00e9culaire des Virus \u00e0 ARN, GMVR: Institut Pasteur, UMR CNRS 3569, Universit\u00e9 de Paris, Paris, France"],"affiliations":[{"raw_affiliation_string":"Centre National de R\u00e9f\u00e9rence des Virus des infections respiratoires (dont la grippe), Institut Pasteur, Paris, France","institution_ids":["https://openalex.org/I157536573"]},{"raw_affiliation_string":"Unit\u00e9 de G\u00e9n\u00e9tique Mol\u00e9culaire des Virus \u00e0 ARN, GMVR: Institut Pasteur, UMR CNRS 3569, Universit\u00e9 de Paris, Paris, France","institution_ids":["https://openalex.org/I157536573","https://openalex.org/I204730241","https://openalex.org/I1294671590"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5080451499","display_name":"J\u00e9r\u00e9mie Guedj","orcid":"https://orcid.org/0000-0002-5534-5482"},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I204730241","display_name":"Universit\u00e9 Paris Cit\u00e9","ror":"https://ror.org/05f82e368","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"J\u00e9r\u00e9mie Guedj","raw_affiliation_strings":["Universit\u00e9 de Paris, IAME, INSERM, Paris, France"],"affiliations":[{"raw_affiliation_string":"Universit\u00e9 de Paris, IAME, INSERM, Paris, France","institution_ids":["https://openalex.org/I204730241","https://openalex.org/I154526488"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":27,"corresponding_author_ids":["https://openalex.org/A5003970120"],"corresponding_institution_ids":["https://openalex.org/I154526488","https://openalex.org/I204730241"],"apc_list":{"value":2655,"currency":"USD","value_usd":2655},"apc_paid":{"value":2072,"currency":"EUR","value_usd":2234},"fwci":3.3161,"has_fulltext":false,"cited_by_count":63,"citation_normalized_percentile":{"value":0.93777922,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"17","issue":"3","first_page":"e1008785","last_page":"e1008785"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10118","display_name":"SARS-CoV-2 and COVID-19 Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10118","display_name":"SARS-CoV-2 and COVID-19 Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10410","display_name":"COVID-19 epidemiological studies","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2611","display_name":"Modeling and Simulation"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10041","display_name":"COVID-19 Clinical Research Studies","score":0.9980999827384949,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/viral-load","display_name":"Viral load","score":0.8451635837554932},{"id":"https://openalex.org/keywords/virology","display_name":"Virology","score":0.5730534195899963},{"id":"https://openalex.org/keywords/severe-acute-respiratory-syndrome-coronavirus-2","display_name":"Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)","score":0.5722715854644775},{"id":"https://openalex.org/keywords/viral-pneumonia","display_name":"Viral pneumonia","score":0.5384876728057861},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.5319721102714539},{"id":"https://openalex.org/keywords/viral-shedding","display_name":"Viral shedding","score":0.5303170084953308},{"id":"https://openalex.org/keywords/virus","display_name":"Virus","score":0.5267307758331299},{"id":"https://openalex.org/keywords/basic-reproduction-number","display_name":"Basic reproduction number","score":0.49840855598449707},{"id":"https://openalex.org/keywords/immunology","display_name":"Immunology","score":0.49046799540519714},{"id":"https://openalex.org/keywords/coronavirus-disease-2019","display_name":"Coronavirus disease 2019 (COVID-19)","score":0.4416114091873169},{"id":"https://openalex.org/keywords/viral-replication","display_name":"Viral replication","score":0.433852881193161},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.3314662277698517},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.1705850064754486},{"id":"https://openalex.org/keywords/infectious-disease","display_name":"Infectious disease (medical specialty)","score":0.08110913634300232}],"concepts":[{"id":"https://openalex.org/C142462285","wikidata":"https://www.wikidata.org/wiki/Q2528140","display_name":"Viral load","level":3,"score":0.8451635837554932},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.5730534195899963},{"id":"https://openalex.org/C3007834351","wikidata":"https://www.wikidata.org/wiki/Q82069695","display_name":"Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)","level":5,"score":0.5722715854644775},{"id":"https://openalex.org/C2778158872","wikidata":"https://www.wikidata.org/wiki/Q2603200","display_name":"Viral pneumonia","level":5,"score":0.5384876728057861},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5319721102714539},{"id":"https://openalex.org/C12914427","wikidata":"https://www.wikidata.org/wiki/Q7933612","display_name":"Viral shedding","level":3,"score":0.5303170084953308},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.5267307758331299},{"id":"https://openalex.org/C204264503","wikidata":"https://www.wikidata.org/wiki/Q901464","display_name":"Basic reproduction number","level":3,"score":0.49840855598449707},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.49046799540519714},{"id":"https://openalex.org/C3008058167","wikidata":"https://www.wikidata.org/wiki/Q84263196","display_name":"Coronavirus disease 2019 (COVID-19)","level":4,"score":0.4416114091873169},{"id":"https://openalex.org/C140704245","wikidata":"https://www.wikidata.org/wiki/Q3933202","display_name":"Viral replication","level":3,"score":0.433852881193161},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3314662277698517},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1705850064754486},{"id":"https://openalex.org/C524204448","wikidata":"https://www.wikidata.org/wiki/Q788926","display_name":"Infectious disease (medical specialty)","level":3,"score":0.08110913634300232},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.0},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000086382","descriptor_name":"COVID-19","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D000086382","descriptor_name":"COVID-19","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D000086382","descriptor_name":"COVID-19","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D000086382","descriptor_name":"COVID-19","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D000086382","descriptor_name":"COVID-19","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D000086382","descriptor_name":"COVID-19","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D000086382","descriptor_name":"COVID-19","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D000086382","descriptor_name":"COVID-19","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D000086382","descriptor_name":"COVID-19","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D000086382","descriptor_name":"COVID-19","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D000086382","descriptor_name":"COVID-19","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D000086382","descriptor_name":"COVID-19","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D000086382","descriptor_name":"COVID-19","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D000086382","descriptor_name":"COVID-19","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D000086382","descriptor_name":"COVID-19","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D000086382","descriptor_name":"COVID-19","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D000086382","descriptor_name":"COVID-19","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D000086382","descriptor_name":"COVID-19","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D000086382","descriptor_name":"COVID-19","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D000086382","descriptor_name":"COVID-19","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D000086382","descriptor_name":"COVID-19","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D000086402","descriptor_name":"SARS-CoV-2","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D000086402","descriptor_name":"SARS-CoV-2","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D000086402","descriptor_name":"SARS-CoV-2","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D000086402","descriptor_name":"SARS-CoV-2","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D000086402","descriptor_name":"SARS-CoV-2","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D000086402","descriptor_name":"SARS-CoV-2","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D000086402","descriptor_name":"SARS-CoV-2","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D000086402","descriptor_name":"SARS-CoV-2","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D000086402","descriptor_name":"SARS-CoV-2","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D000086402","descriptor_name":"SARS-CoV-2","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D000086402","descriptor_name":"SARS-CoV-2","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D000086402","descriptor_name":"SARS-CoV-2","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D000086402","descriptor_name":"SARS-CoV-2","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D000086402","descriptor_name":"SARS-CoV-2","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000998","descriptor_name":"Antiviral Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000998","descriptor_name":"Antiviral Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000998","descriptor_name":"Antiviral Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000998","descriptor_name":"Antiviral Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000998","descriptor_name":"Antiviral Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000998","descriptor_name":"Antiviral Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000998","descriptor_name":"Antiviral Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008252","descriptor_name":"Macaca fascicularis","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D008252","descriptor_name":"Macaca fascicularis","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D008252","descriptor_name":"Macaca fascicularis","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D008252","descriptor_name":"Macaca fascicularis","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D008252","descriptor_name":"Macaca fascicularis","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D008252","descriptor_name":"Macaca fascicularis","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D008252","descriptor_name":"Macaca fascicularis","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D009305","descriptor_name":"Nasopharynx","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D009305","descriptor_name":"Nasopharynx","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D009305","descriptor_name":"Nasopharynx","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D009305","descriptor_name":"Nasopharynx","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D009305","descriptor_name":"Nasopharynx","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D009305","descriptor_name":"Nasopharynx","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D009305","descriptor_name":"Nasopharynx","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D014132","descriptor_name":"Trachea","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D014132","descriptor_name":"Trachea","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D014132","descriptor_name":"Trachea","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D014132","descriptor_name":"Trachea","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D014132","descriptor_name":"Trachea","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D014132","descriptor_name":"Trachea","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D014132","descriptor_name":"Trachea","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D014779","descriptor_name":"Virus Replication","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D014779","descriptor_name":"Virus Replication","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D014779","descriptor_name":"Virus Replication","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D014779","descriptor_name":"Virus Replication","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D014779","descriptor_name":"Virus Replication","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D014779","descriptor_name":"Virus Replication","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D014779","descriptor_name":"Virus Replication","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D016207","descriptor_name":"Cytokines","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D016207","descriptor_name":"Cytokines","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D016207","descriptor_name":"Cytokines","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D016207","descriptor_name":"Cytokines","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D016207","descriptor_name":"Cytokines","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D016207","descriptor_name":"Cytokines","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D016207","descriptor_name":"Cytokines","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D019562","descriptor_name":"Viral Load","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019562","descriptor_name":"Viral Load","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019562","descriptor_name":"Viral Load","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019562","descriptor_name":"Viral Load","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019562","descriptor_name":"Viral Load","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019562","descriptor_name":"Viral Load","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019562","descriptor_name":"Viral Load","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D050936","descriptor_name":"Basic Reproduction Number","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D050936","descriptor_name":"Basic Reproduction Number","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D050936","descriptor_name":"Basic Reproduction Number","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D050936","descriptor_name":"Basic Reproduction Number","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D050936","descriptor_name":"Basic Reproduction Number","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D050936","descriptor_name":"Basic Reproduction Number","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D050936","descriptor_name":"Basic Reproduction Number","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":7,"locations":[{"id":"doi:10.1371/journal.pcbi.1008785","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1008785","pdf_url":null,"source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},{"id":"pmid:33730053","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33730053","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS computational biology","raw_type":null},{"id":"pmh:oai:HAL:hal-03275759v1","is_oa":false,"landing_page_url":"https://hal.archives-ouvertes.fr/hal-03275759","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL (Le Centre pour la Communication Scientifique Directe)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1294671590","host_organization_name":"Centre National de la Recherche Scientifique","host_organization_lineage":["https://openalex.org/I1294671590"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ISSN: 1553-734X","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:HAL:pasteur-03207908v1","is_oa":true,"landing_page_url":"https://pasteur.hal.science/pasteur-03207908","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL (Le Centre pour la Communication Scientifique Directe)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1294671590","host_organization_name":"Centre National de la Recherche Scientifique","host_organization_lineage":["https://openalex.org/I1294671590"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Computational Biology, 2021, 17 (3), pp.e1008785. ⟨10.1371/journal.pcbi.1008785⟩","raw_type":"Journal articles"},{"id":"pmh:oai:doaj.org/article:0fa0b9d2f5e5421e8a4721a215607b84","is_oa":true,"landing_page_url":"https://doaj.org/article/0fa0b9d2f5e5421e8a4721a215607b84","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Computational Biology, Vol 17, Iss 3, p e1008785 (2021)","raw_type":"article"},{"id":"pmh:oai:oskar-bordeaux.fr:20.500.12278/40404","is_oa":true,"landing_page_url":"https://oskar-bordeaux.fr/handle/20.500.12278/40404","pdf_url":null,"source":{"id":"https://openalex.org/S4306402569","display_name":"Oskar-Bordeaux (Universite de Bordeaux)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article de revue"},{"id":"pmh:oai:pubmedcentral.nih.gov:8007039","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8007039","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Comput Biol","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1371/journal.pcbi.1008785","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1008785","pdf_url":null,"source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.44999998807907104,"display_name":"Good health and well-being"}],"awards":[{"id":"https://openalex.org/G1128133788","display_name":null,"funder_award_id":"Gates","funder_id":"https://openalex.org/F4320306137","funder_display_name":"Bill and Melinda Gates Foundation"},{"id":"https://openalex.org/G1734005478","display_name":null,"funder_award_id":"INV- 017335","funder_id":"https://openalex.org/F4320306137","funder_display_name":"Bill and Melinda Gates Foundation"},{"id":"https://openalex.org/G4423494656","display_name":null,"funder_award_id":"TheraCoV ANR-20-COVI-0018","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"},{"id":"https://openalex.org/G7863193404","display_name":null,"funder_award_id":"INV-017335","funder_id":"https://openalex.org/F4320306137","funder_display_name":"Bill and Melinda Gates Foundation"}],"funders":[{"id":"https://openalex.org/F4320306137","display_name":"Bill and Melinda Gates Foundation","ror":"https://ror.org/0456r8d26"},{"id":"https://openalex.org/F4320320883","display_name":"Agence Nationale de la Recherche","ror":"https://ror.org/00rbzpz17"},{"id":"https://openalex.org/F4320320893","display_name":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale","ror":"https://ror.org/02vjkv261"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":32,"referenced_works":["https://openalex.org/W1968541274","https://openalex.org/W1997792006","https://openalex.org/W2014184548","https://openalex.org/W2037438924","https://openalex.org/W2065820141","https://openalex.org/W2073234751","https://openalex.org/W2109977701","https://openalex.org/W2741511733","https://openalex.org/W2746274580","https://openalex.org/W2793022939","https://openalex.org/W2794468699","https://openalex.org/W2885985538","https://openalex.org/W2893315858","https://openalex.org/W3002108456","https://openalex.org/W3005629417","https://openalex.org/W3008090866","https://openalex.org/W3010338568","https://openalex.org/W3014095365","https://openalex.org/W3016746341","https://openalex.org/W3017315642","https://openalex.org/W3019768930","https://openalex.org/W3026558549","https://openalex.org/W3035417125","https://openalex.org/W3036931136","https://openalex.org/W3045220852","https://openalex.org/W3087588044","https://openalex.org/W3092503590","https://openalex.org/W3118175554","https://openalex.org/W3120628363","https://openalex.org/W3126652124","https://openalex.org/W3134790283","https://openalex.org/W4254454535"],"related_works":["https://openalex.org/W2587999459","https://openalex.org/W3045863127","https://openalex.org/W2141886448","https://openalex.org/W2416583051","https://openalex.org/W3090012918","https://openalex.org/W4386554239","https://openalex.org/W2102326449","https://openalex.org/W3207308314","https://openalex.org/W2032099305","https://openalex.org/W4281492369"],"abstract_inverted_index":{"Non-human":[0],"primates":[1],"infected":[2,39,69],"with":[3,74,80,101],"SARS-CoV-2":[4,136],"exhibit":[5],"mild":[6,104,145],"clinical":[7],"signs.":[8],"Here":[9],"we":[10,111],"used":[11],"a":[12,42,49,75,91,114],"mathematical":[13],"model":[14,143],"to":[15,90,94,151],"characterize":[16],"in":[17,22,59,103,140],"detail":[18],"the":[19,153],"viral":[20,31,67,95,120,123,127,137],"dynamics":[21],"31":[23],"cynomolgus":[24],"macaques":[25],"for":[26],"which":[27],"nasopharyngeal":[28,60],"and":[29,48,57,61,87,147],"tracheal":[30,62],"load":[32],"were":[33,71],"frequently":[34],"assessed.":[35],"We":[36],"identified":[37],"that":[38,113],"cells":[40,70],"had":[41],"large":[43],"burst":[44],"size":[45],"(>104":[46],"virus)":[47],"within-host":[50],"reproductive":[51],"basic":[52],"number":[53],"of":[54,77,97,119,135,144,155],"approximately":[55],"6":[56],"4":[58],"compartment,":[63],"respectively.":[64],"After":[65],"peak":[66],"load,":[68],"rapidly":[72],"lost":[73],"half-life":[76],"9":[78],"hours,":[79],"no":[81],"significant":[82],"association":[83],"between":[84],"cytokine":[85],"elevation":[86],"clearance,":[88],"leading":[89],"median":[92],"time":[93],"clearance":[96],"10":[98],"days,":[99],"consistent":[100],"observations":[102],"human":[105],"infections.":[106],"Given":[107],"these":[108],"parameter":[109],"estimates,":[110],"predict":[112],"prophylactic":[115],"treatment":[116],"blocking":[117],"90%":[118],"production":[121],"or":[122],"infection":[124,146],"could":[125],"prevent":[126],"growth.":[128],"In":[129],"conclusion,":[130],"our":[131],"results":[132],"provide":[133,149],"estimates":[134],"kinetic":[138],"parameters":[139],"an":[141],"experimental":[142],"they":[148],"means":[150],"assess":[152],"efficacy":[154],"future":[156],"antiviral":[157],"treatments.":[158]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":10},{"year":2024,"cited_by_count":8},{"year":2023,"cited_by_count":14},{"year":2022,"cited_by_count":19},{"year":2021,"cited_by_count":10}],"updated_date":"2026-03-27T05:58:40.876381","created_date":"2025-10-10T00:00:00"}