{"id":"https://openalex.org/W3020054769","doi":"https://doi.org/10.1371/journal.pcbi.1007851","title":"LMSM: A\u00a0modular approach for identifying lncRNA related miRNA sponge modules in breast cancer","display_name":"LMSM: A\u00a0modular approach for identifying lncRNA related miRNA sponge modules in breast cancer","publication_year":2020,"publication_date":"2020-04-23","ids":{"openalex":"https://openalex.org/W3020054769","doi":"https://doi.org/10.1371/journal.pcbi.1007851","mag":"3020054769","pmid":"https://pubmed.ncbi.nlm.nih.gov/32324747"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pcbi.1007851","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1007851","pdf_url":null,"source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1371/journal.pcbi.1007851","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100702169","display_name":"Junpeng Zhang","orcid":"https://orcid.org/0000-0001-6127-9701"},"institutions":[{"id":"https://openalex.org/I150229711","display_name":"University of Electronic Science and Technology of China","ror":"https://ror.org/04qr3zq92","country_code":"CN","type":"education","lineage":["https://openalex.org/I150229711"]},{"id":"https://openalex.org/I6593398","display_name":"Dali University","ror":"https://ror.org/02y7rck89","country_code":"CN","type":"education","lineage":["https://openalex.org/I6593398"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Junpeng Zhang","raw_affiliation_strings":["Center for Informational Biology, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, Sichuan, China","School of Engineering, Dali University, Dali, Yunnan, China"],"raw_orcid":"https://orcid.org/0000-0001-6127-9701","affiliations":[{"raw_affiliation_string":"Center for Informational Biology, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, Sichuan, China","institution_ids":["https://openalex.org/I150229711"]},{"raw_affiliation_string":"School of Engineering, Dali University, Dali, Yunnan, China","institution_ids":["https://openalex.org/I6593398"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071137947","display_name":"Taosheng Xu","orcid":"https://orcid.org/0000-0001-8283-7274"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I2802624667","display_name":"Hefei Institutes of Physical Science","ror":"https://ror.org/046n57345","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I2802624667"]},{"id":"https://openalex.org/I4210099079","display_name":"Institute of Intelligent Machines","ror":"https://ror.org/00w0qep84","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I2802624667","https://openalex.org/I4210099079"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Taosheng Xu","raw_affiliation_strings":["Institute of Intelligent Machines, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, Anhui, China"],"raw_orcid":"https://orcid.org/0000-0001-8283-7274","affiliations":[{"raw_affiliation_string":"Institute of Intelligent Machines, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, Anhui, China","institution_ids":["https://openalex.org/I2802624667","https://openalex.org/I4210099079","https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100383342","display_name":"Lin Liu","orcid":"https://orcid.org/0000-0003-2843-5738"},"institutions":[{"id":"https://openalex.org/I170239107","display_name":"University of South Australia","ror":"https://ror.org/01p93h210","country_code":"AU","type":"education","lineage":["https://openalex.org/I170239107"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Lin Liu","raw_affiliation_strings":["School of Information Technology and Mathematical Sciences, University of South Australia, Mawson Lakes, SA, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Information Technology and Mathematical Sciences, University of South Australia, Mawson Lakes, SA, Australia","institution_ids":["https://openalex.org/I170239107"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100381600","display_name":"Wu Zhang","orcid":"https://orcid.org/0000-0002-7887-8345"},"institutions":[{"id":"https://openalex.org/I6593398","display_name":"Dali University","ror":"https://ror.org/02y7rck89","country_code":"CN","type":"education","lineage":["https://openalex.org/I6593398"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wu Zhang","raw_affiliation_strings":["School of Agriculture and Biological Sciences, Dali University, Dali, Yunnan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Agriculture and Biological Sciences, Dali University, Dali, Yunnan, China","institution_ids":["https://openalex.org/I6593398"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066637002","display_name":"Chunwen Zhao","orcid":"https://orcid.org/0000-0002-4411-6828"},"institutions":[{"id":"https://openalex.org/I6593398","display_name":"Dali University","ror":"https://ror.org/02y7rck89","country_code":"CN","type":"education","lineage":["https://openalex.org/I6593398"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chunwen Zhao","raw_affiliation_strings":["School of Engineering, Dali University, Dali, Yunnan, China"],"raw_orcid":"https://orcid.org/0000-0002-4411-6828","affiliations":[{"raw_affiliation_string":"School of Engineering, Dali University, Dali, Yunnan, China","institution_ids":["https://openalex.org/I6593398"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064049313","display_name":"Sijing Li","orcid":"https://orcid.org/0000-0003-4741-8407"},"institutions":[{"id":"https://openalex.org/I6593398","display_name":"Dali University","ror":"https://ror.org/02y7rck89","country_code":"CN","type":"education","lineage":["https://openalex.org/I6593398"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Sijing Li","raw_affiliation_strings":["School of Engineering, Dali University, Dali, Yunnan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Engineering, Dali University, Dali, Yunnan, China","institution_ids":["https://openalex.org/I6593398"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012177739","display_name":"Jiuyong Li","orcid":"https://orcid.org/0000-0002-9023-1878"},"institutions":[{"id":"https://openalex.org/I170239107","display_name":"University of South Australia","ror":"https://ror.org/01p93h210","country_code":"AU","type":"education","lineage":["https://openalex.org/I170239107"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Jiuyong Li","raw_affiliation_strings":["School of Information Technology and Mathematical Sciences, University of South Australia, Mawson Lakes, SA, Australia"],"raw_orcid":"https://orcid.org/0000-0002-9023-1878","affiliations":[{"raw_affiliation_string":"School of Information Technology and Mathematical Sciences, University of South Australia, Mawson Lakes, SA, Australia","institution_ids":["https://openalex.org/I170239107"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084502070","display_name":"Nini Rao","orcid":"https://orcid.org/0000-0001-7979-2917"},"institutions":[{"id":"https://openalex.org/I150229711","display_name":"University of Electronic Science and Technology of China","ror":"https://ror.org/04qr3zq92","country_code":"CN","type":"education","lineage":["https://openalex.org/I150229711"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Nini Rao","raw_affiliation_strings":["Center for Informational Biology, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, Sichuan, China"],"raw_orcid":"https://orcid.org/0000-0001-7979-2917","affiliations":[{"raw_affiliation_string":"Center for Informational Biology, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, Sichuan, China","institution_ids":["https://openalex.org/I150229711"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5035846381","display_name":"Thuc Duy Le","orcid":"https://orcid.org/0000-0002-9732-4313"},"institutions":[{"id":"https://openalex.org/I170239107","display_name":"University of South Australia","ror":"https://ror.org/01p93h210","country_code":"AU","type":"education","lineage":["https://openalex.org/I170239107"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"Thuc Duy Le","raw_affiliation_strings":["School of Information Technology and Mathematical Sciences, University of South Australia, Mawson Lakes, SA, Australia"],"raw_orcid":"https://orcid.org/0000-0002-9732-4313","affiliations":[{"raw_affiliation_string":"School of Information Technology and Mathematical Sciences, University of South Australia, Mawson Lakes, SA, Australia","institution_ids":["https://openalex.org/I170239107"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5035846381","https://openalex.org/A5084502070","https://openalex.org/A5100702169"],"corresponding_institution_ids":["https://openalex.org/I150229711","https://openalex.org/I170239107","https://openalex.org/I6593398"],"apc_list":{"value":2655,"currency":"USD","value_usd":2655},"apc_paid":{"value":2655,"currency":"USD","value_usd":2655},"fwci":1.4371,"has_fulltext":false,"cited_by_count":25,"citation_normalized_percentile":{"value":0.80437703,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"16","issue":"4","first_page":"e1007851","last_page":"e1007851"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11482","display_name":"RNA modifications and cancer","score":0.9983000159263611,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11765","display_name":"Circular RNAs in diseases","score":0.9973999857902527,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/modular-design","display_name":"Modular design","score":0.67551589012146},{"id":"https://openalex.org/keywords/sponge","display_name":"Sponge","score":0.6733867526054382},{"id":"https://openalex.org/keywords/breast-cancer","display_name":"Breast cancer","score":0.6387037038803101},{"id":"https://openalex.org/keywords/microrna","display_name":"microRNA","score":0.6239745020866394},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5936387181282043},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.4769286513328552},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.4182940125465393},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.4091228246688843},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.3752068877220154},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.20692050457000732},{"id":"https://openalex.org/keywords/paleontology","display_name":"Paleontology","score":0.09551629424095154},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.06958836317062378},{"id":"https://openalex.org/keywords/programming-language","display_name":"Programming language","score":0.06620243191719055}],"concepts":[{"id":"https://openalex.org/C101468663","wikidata":"https://www.wikidata.org/wiki/Q1620158","display_name":"Modular design","level":2,"score":0.67551589012146},{"id":"https://openalex.org/C2778849931","wikidata":"https://www.wikidata.org/wiki/Q18960","display_name":"Sponge","level":2,"score":0.6733867526054382},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.6387037038803101},{"id":"https://openalex.org/C145059251","wikidata":"https://www.wikidata.org/wiki/Q310899","display_name":"microRNA","level":3,"score":0.6239745020866394},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5936387181282043},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4769286513328552},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.4182940125465393},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4091228246688843},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3752068877220154},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.20692050457000732},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.09551629424095154},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.06958836317062378},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.06620243191719055}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D062085","descriptor_name":"RNA, Long Noncoding","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D062085","descriptor_name":"RNA, Long Noncoding","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D062085","descriptor_name":"RNA, Long Noncoding","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D062085","descriptor_name":"RNA, Long Noncoding","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D062085","descriptor_name":"RNA, Long Noncoding","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D062085","descriptor_name":"RNA, Long Noncoding","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D062085","descriptor_name":"RNA, Long Noncoding","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D062085","descriptor_name":"RNA, Long Noncoding","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D062085","descriptor_name":"RNA, Long Noncoding","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":7,"locations":[{"id":"doi:10.1371/journal.pcbi.1007851","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1007851","pdf_url":null,"source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},{"id":"pmid:32324747","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32324747","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS computational biology","raw_type":null},{"id":"pmh:oai:RePEc:plo:pcbi00:1007851","is_oa":false,"landing_page_url":"https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1007851","pdf_url":null,"source":{"id":"https://openalex.org/S4306401271","display_name":"RePEc: Research Papers in Economics","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I77793887","host_organization_name":"Federal Reserve Bank of St. Louis","host_organization_lineage":["https://openalex.org/I77793887"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"},{"id":"pmh:oai:doaj.org/article:057e9998ffc34176bd2f322c1f6ab136","is_oa":true,"landing_page_url":"https://doaj.org/article/057e9998ffc34176bd2f322c1f6ab136","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Computational Biology, Vol 16, Iss 4, p e1007851 (2020)","raw_type":"article"},{"id":"pmh:oai:figshare.com:article/12184446","is_oa":true,"landing_page_url":null,"pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"},{"id":"pmh:oai:pubmedcentral.nih.gov:7200020","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7200020","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Comput Biol","raw_type":"Text"},{"id":"pmh:oai:urm_publish:9916395408201831","is_oa":false,"landing_page_url":"https://hdl.handle.net/11541.2/142458","pdf_url":null,"source":{"id":"https://openalex.org/S4306402528","display_name":"UniSA Research Outputs Repository (University of South Australia)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I170239107","host_organization_name":"University of South Australia","host_organization_lineage":["https://openalex.org/I170239107"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"text"}],"best_oa_location":{"id":"doi:10.1371/journal.pcbi.1007851","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1007851","pdf_url":null,"source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8600000143051147}],"awards":[{"id":"https://openalex.org/G2432993869","display_name":null,"funder_award_id":"61872405, 61720106004","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G2813530640","display_name":null,"funder_award_id":"61902372","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G3273648886","display_name":null,"funder_award_id":"61872405","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G4619005080","display_name":null,"funder_award_id":"2017FB099","funder_id":"https://openalex.org/F4320332533","funder_display_name":"Applied Basic Research Foundation of Yunnan Province"},{"id":"https://openalex.org/G462952484","display_name":null,"funder_award_id":"DP170101306","funder_id":"https://openalex.org/F4320334704","funder_display_name":"Australian Research Council"},{"id":"https://openalex.org/G5269616794","display_name":null,"funder_award_id":"61720106004","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5433873009","display_name":null,"funder_award_id":"61702069, 61963001","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6012743596","display_name":null,"funder_award_id":"61702069","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6024985873","display_name":null,"funder_award_id":"1123042","funder_id":"https://openalex.org/F4320334704","funder_display_name":"Australian Research Council"},{"id":"https://openalex.org/G7664388442","display_name":null,"funder_award_id":"61963001","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G826466753","display_name":null,"funder_award_id":"1123042","funder_id":"https://openalex.org/F4320334705","funder_display_name":"National Health and Medical Research Council"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320332533","display_name":"Applied Basic Research Foundation of Yunnan Province","ror":"https://ror.org/030jhb479"},{"id":"https://openalex.org/F4320334704","display_name":"Australian Research Council","ror":"https://ror.org/05mmh0f86"},{"id":"https://openalex.org/F4320334705","display_name":"National Health and Medical Research Council","ror":"https://ror.org/011kf5r70"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":66,"referenced_works":["https://openalex.org/W41957589","https://openalex.org/W55768394","https://openalex.org/W144423133","https://openalex.org/W1570622790","https://openalex.org/W1966327575","https://openalex.org/W1972822237","https://openalex.org/W1986705681","https://openalex.org/W2014946489","https://openalex.org/W2025341678","https://openalex.org/W2035055162","https://openalex.org/W2039473892","https://openalex.org/W2046387002","https://openalex.org/W2062989416","https://openalex.org/W2098290597","https://openalex.org/W2104508998","https://openalex.org/W2107772748","https://openalex.org/W2108000084","https://openalex.org/W2110065044","https://openalex.org/W2117977572","https://openalex.org/W2124166542","https://openalex.org/W2124756133","https://openalex.org/W2130687298","https://openalex.org/W2132619562","https://openalex.org/W2133658633","https://openalex.org/W2134629862","https://openalex.org/W2137734450","https://openalex.org/W2141831115","https://openalex.org/W2143662314","https://openalex.org/W2153635508","https://openalex.org/W2159707944","https://openalex.org/W2167190345","https://openalex.org/W2171398108","https://openalex.org/W2172358623","https://openalex.org/W2174734928","https://openalex.org/W2220159479","https://openalex.org/W2223740898","https://openalex.org/W2259090596","https://openalex.org/W2280882096","https://openalex.org/W2336850185","https://openalex.org/W2410060109","https://openalex.org/W2515619833","https://openalex.org/W2537679995","https://openalex.org/W2558715006","https://openalex.org/W2578321666","https://openalex.org/W2613389355","https://openalex.org/W2735687500","https://openalex.org/W2765372324","https://openalex.org/W2784570320","https://openalex.org/W2808829302","https://openalex.org/W2809365035","https://openalex.org/W2810683051","https://openalex.org/W2883645365","https://openalex.org/W2891177935","https://openalex.org/W2894580910","https://openalex.org/W2895679848","https://openalex.org/W2897825874","https://openalex.org/W2898335785","https://openalex.org/W2899830787","https://openalex.org/W2900841953","https://openalex.org/W2919378721","https://openalex.org/W2952615074","https://openalex.org/W2953211530","https://openalex.org/W2959791350","https://openalex.org/W4237723258","https://openalex.org/W4255156463","https://openalex.org/W6632445771"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2015854251","https://openalex.org/W2122538981","https://openalex.org/W2021188643","https://openalex.org/W614364637","https://openalex.org/W4308250236","https://openalex.org/W2338797498","https://openalex.org/W2326616893","https://openalex.org/W2239222391","https://openalex.org/W2057742104"],"abstract_inverted_index":{"Until":[0],"now,":[1],"existing":[2],"methods":[3,43],"for":[4],"identifying":[5,195,218],"lncRNA":[6,14,46,196],"related":[7,15,47,62,197],"miRNA":[8,16,28,48,72,198,208],"sponge":[9,17,49,94,199,237],"modules":[10,126,155,168,181],"mainly":[11],"rely":[12],"on":[13,91],"interaction":[18],"networks,":[19],"which":[20],"may":[21],"not":[22],"provide":[23],"a":[24,37,56,116,213,228],"full":[25],"picture":[26],"of":[27,40,87,124,134,140,153,166,179,236],"sponging":[29,73],"activities":[30,74],"in":[31,75,130,182,194,217],"biological":[32,76,177],"conditions.":[33],"Hence":[34],"there":[35],"is":[36,169,192,227],"strong":[38],"need":[39],"new":[41],"computational":[42],"to":[44,59,83,102,206,231],"identify":[45,60],"modules.":[50,200,220],"In":[51],"this":[52],"work,":[53],"we":[54,118],"propose":[55],"framework,":[57],"LMSM,":[58],"LncRNA":[61],"MiRNA":[63],"Sponge":[64],"Modules":[65],"from":[66,109,239],"heterogeneous":[67,240],"data.":[68,241],"To":[69],"understand":[70],"the":[71,85,88,92,103,122,141,164,176],"conditions,":[77],"LMSM":[78,101,125,149,154,167,180,191,202,211,226],"uses":[79],"gene":[80],"expression":[81],"data":[82],"evaluate":[84],"influence":[86],"shared":[89],"miRNAs":[90,143],"clustered":[93],"lncRNAs":[95,238],"and":[96,132,151],"mRNAs.":[97],"We":[98],"have":[99,119],"applied":[100],"human":[104],"breast":[105],"cancer":[106],"(BRCA)":[107],"dataset":[108],"The":[110,186],"Cancer":[111],"Genome":[112],"Atlas":[113],"(TCGA).":[114],"As":[115],"result,":[117],"found":[120],"that":[121,163,190,225],"majority":[123],"are":[127,136,156],"significantly":[128,170],"implicated":[129],"BRCA":[131,137,184],"most":[133],"them":[135],"subtype-specific.":[138],"Most":[139],"mediating":[142],"act":[144],"as":[145],"crosslinks":[146],"across":[147],"different":[148],"modules,":[150],"all":[152],"statistically":[157],"significant.":[158],"Multi-label":[159],"classification":[160],"analysis":[161],"shows":[162,224],"performance":[165],"higher":[171],"than":[172],"baseline's":[173],"performance,":[174],"indicating":[175],"meanings":[178],"classifying":[183],"subtypes.":[185],"consistent":[187],"results":[188],"suggest":[189],"robust":[193],"Moreover,":[201],"can":[203],"be":[204],"used":[205],"predict":[207],"targets.":[209],"Finally,":[210],"outperforms":[212],"graph":[214],"clustering-based":[215],"strategy":[216],"BRCA-related":[219],"Altogether,":[221],"our":[222],"study":[223],"promising":[229],"method":[230],"investigate":[232],"modular":[233],"regulatory":[234],"mechanism":[235]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":9},{"year":2021,"cited_by_count":6}],"updated_date":"2026-01-13T01:12:25.745995","created_date":"2020-05-01T00:00:00"}