{"id":"https://openalex.org/W3043588201","doi":"https://doi.org/10.1371/journal.pcbi.1007760","title":"A novel riboswitch classification based on imbalanced sequences achieved by machine learning","display_name":"A novel riboswitch classification based on imbalanced sequences achieved by machine learning","publication_year":2020,"publication_date":"2020-07-20","ids":{"openalex":"https://openalex.org/W3043588201","doi":"https://doi.org/10.1371/journal.pcbi.1007760","mag":"3043588201","pmid":"https://pubmed.ncbi.nlm.nih.gov/32687488"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pcbi.1007760","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1007760","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1007760&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1007760&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5063073571","display_name":"Solomon Beyene","orcid":null},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Solomon Shiferaw Beyene","raw_affiliation_strings":["Department of Bioinformatics, College of Life Sciences, Zhejiang University, Hangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Bioinformatics, College of Life Sciences, Zhejiang University, Hangzhou, China","institution_ids":["https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084524512","display_name":"Tianyi Ling","orcid":"https://orcid.org/0000-0001-8909-8718"},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Tianyi Ling","raw_affiliation_strings":["Department of Bioinformatics, College of Life Sciences, Zhejiang University, Hangzhou, China","School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China"],"raw_orcid":"https://orcid.org/0000-0001-8909-8718","affiliations":[{"raw_affiliation_string":"Department of Bioinformatics, College of Life Sciences, Zhejiang University, Hangzhou, China","institution_ids":["https://openalex.org/I76130692"]},{"raw_affiliation_string":"School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China","institution_ids":["https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040661461","display_name":"Blagoj Ristevski","orcid":"https://orcid.org/0000-0002-8356-1203"},"institutions":[{"id":"https://openalex.org/I2802401942","display_name":"University \"St. Kliment Ohridski\" - Bitola","ror":"https://ror.org/04161ta68","country_code":"MK","type":"education","lineage":["https://openalex.org/I2802401942"]}],"countries":["MK"],"is_corresponding":false,"raw_author_name":"Blagoj Ristevski","raw_affiliation_strings":["Faculty of Information and Communication Technologies, Bitola, St. Kliment Ohridski University Bitola, ul. Partizanska Bitola, Republic of North Macedonia"],"raw_orcid":"https://orcid.org/0000-0002-8356-1203","affiliations":[{"raw_affiliation_string":"Faculty of Information and Communication Technologies, Bitola, St. Kliment Ohridski University Bitola, ul. Partizanska Bitola, Republic of North Macedonia","institution_ids":["https://openalex.org/I2802401942"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100423292","display_name":"Ming Chen","orcid":"https://orcid.org/0000-0002-9677-1699"},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Ming Chen","raw_affiliation_strings":["Department of Bioinformatics, College of Life Sciences, Zhejiang University, Hangzhou, China"],"raw_orcid":"https://orcid.org/0000-0002-9677-1699","affiliations":[{"raw_affiliation_string":"Department of Bioinformatics, College of Life Sciences, Zhejiang University, Hangzhou, China","institution_ids":["https://openalex.org/I76130692"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5100423292"],"corresponding_institution_ids":["https://openalex.org/I76130692"],"apc_list":{"value":2655,"currency":"USD","value_usd":2655},"apc_paid":{"value":2655,"currency":"USD","value_usd":2655},"fwci":0.1672,"has_fulltext":true,"cited_by_count":4,"citation_normalized_percentile":{"value":0.50130542,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":95},"biblio":{"volume":"16","issue":"7","first_page":"e1007760","last_page":"e1007760"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9900000095367432,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9884999990463257,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/riboswitch","display_name":"Riboswitch","score":0.9356734752655029},{"id":"https://openalex.org/keywords/overfitting","display_name":"Overfitting","score":0.7789156436920166},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.6390522122383118},{"id":"https://openalex.org/keywords/aptamer","display_name":"Aptamer","score":0.5695915222167969},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.5437288880348206},{"id":"https://openalex.org/keywords/classifier","display_name":"Classifier (UML)","score":0.5377208590507507},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.49663883447647095},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.476727157831192},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.43624746799468994},{"id":"https://openalex.org/keywords/source-code","display_name":"Source code","score":0.41030097007751465},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.3700101971626282},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.2128920555114746},{"id":"https://openalex.org/keywords/non-coding-rna","display_name":"Non-coding RNA","score":0.16304290294647217},{"id":"https://openalex.org/keywords/rna","display_name":"RNA","score":0.1426829695701599},{"id":"https://openalex.org/keywords/artificial-neural-network","display_name":"Artificial neural network","score":0.10137471556663513},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.09803533554077148}],"concepts":[{"id":"https://openalex.org/C148625055","wikidata":"https://www.wikidata.org/wiki/Q418840","display_name":"Riboswitch","level":5,"score":0.9356734752655029},{"id":"https://openalex.org/C22019652","wikidata":"https://www.wikidata.org/wiki/Q331309","display_name":"Overfitting","level":3,"score":0.7789156436920166},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.6390522122383118},{"id":"https://openalex.org/C128972844","wikidata":"https://www.wikidata.org/wiki/Q418722","display_name":"Aptamer","level":2,"score":0.5695915222167969},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.5437288880348206},{"id":"https://openalex.org/C95623464","wikidata":"https://www.wikidata.org/wiki/Q1096149","display_name":"Classifier (UML)","level":2,"score":0.5377208590507507},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.49663883447647095},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.476727157831192},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.43624746799468994},{"id":"https://openalex.org/C43126263","wikidata":"https://www.wikidata.org/wiki/Q128751","display_name":"Source code","level":2,"score":0.41030097007751465},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3700101971626282},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2128920555114746},{"id":"https://openalex.org/C194993378","wikidata":"https://www.wikidata.org/wiki/Q427087","display_name":"Non-coding RNA","level":4,"score":0.16304290294647217},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.1426829695701599},{"id":"https://openalex.org/C50644808","wikidata":"https://www.wikidata.org/wiki/Q192776","display_name":"Artificial neural network","level":2,"score":0.10137471556663513},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.09803533554077148},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017423","descriptor_name":"Sequence Analysis, RNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017423","descriptor_name":"Sequence Analysis, RNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017423","descriptor_name":"Sequence Analysis, RNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017423","descriptor_name":"Sequence Analysis, RNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D058928","descriptor_name":"Riboswitch","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D058928","descriptor_name":"Riboswitch","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D058928","descriptor_name":"Riboswitch","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D058928","descriptor_name":"Riboswitch","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1371/journal.pcbi.1007760","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1007760","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1007760&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},{"id":"pmid:32687488","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32687488","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS computational biology","raw_type":null},{"id":"pmh:oai:RePEc:plo:pcbi00:1007760","is_oa":false,"landing_page_url":"https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1007760","pdf_url":null,"source":{"id":"https://openalex.org/S4306401271","display_name":"RePEc: Research Papers in Economics","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I77793887","host_organization_name":"Federal Reserve Bank of St. Louis","host_organization_lineage":["https://openalex.org/I77793887"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"},{"id":"pmh:oai:doaj.org/article:1c6e271f93794e42982b2000d9b2bc4d","is_oa":true,"landing_page_url":"https://doaj.org/article/1c6e271f93794e42982b2000d9b2bc4d","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Computational Biology, Vol 16, Iss 7, p e1007760 (2020)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7392346","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7392346","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Comput Biol","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1371/journal.pcbi.1007760","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1007760","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1007760&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G2729744253","display_name":null,"funder_award_id":"31771477","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G3799653218","display_name":null,"funder_award_id":"31771477","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"},{"id":"https://openalex.org/G4265148366","display_name":null,"funder_award_id":"31571366","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"},{"id":"https://openalex.org/G4537801949","display_name":null,"funder_award_id":"2018YFC0310602","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"},{"id":"https://openalex.org/G5220452828","display_name":null,"funder_award_id":"31771477","funder_id":"https://openalex.org/F4320329854","funder_display_name":"Jiangsu Collaborative Innovation Center for Modern Crop Production"},{"id":"https://openalex.org/G6633787826","display_name":null,"funder_award_id":"2018YFC0310602","funder_id":"https://openalex.org/F4320329854","funder_display_name":"Jiangsu Collaborative Innovation Center for Modern Crop Production"},{"id":"https://openalex.org/G7097571926","display_name":null,"funder_award_id":"2018YFC0310602","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7355969415","display_name":null,"funder_award_id":"2016YFA0501704","funder_id":"https://openalex.org/F4320329854","funder_display_name":"Jiangsu Collaborative Innovation Center for Modern Crop Production"},{"id":"https://openalex.org/G8115334579","display_name":null,"funder_award_id":"2016YFA0501704","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"},{"id":"https://openalex.org/G8180724134","display_name":null,"funder_award_id":"31571366","funder_id":"https://openalex.org/F4320329854","funder_display_name":"Jiangsu Collaborative Innovation Center for Modern Crop Production"},{"id":"https://openalex.org/G8205675081","display_name":null,"funder_award_id":"31571366","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G8484657908","display_name":null,"funder_award_id":"2016YFA0501704","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320329854","display_name":"Jiangsu Collaborative Innovation Center for Modern Crop Production","ror":null},{"id":"https://openalex.org/F4320335564","display_name":"Chinese Government Scholarship","ror":null},{"id":"https://openalex.org/F4320335777","display_name":"National Key Research and Development Program of China","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3043588201.pdf","grobid_xml":"https://content.openalex.org/works/W3043588201.grobid-xml"},"referenced_works_count":91,"referenced_works":["https://openalex.org/W178767945","https://openalex.org/W1510526001","https://openalex.org/W1570448133","https://openalex.org/W1678356000","https://openalex.org/W1941659294","https://openalex.org/W1967102258","https://openalex.org/W1969580383","https://openalex.org/W1972139720","https://openalex.org/W1972708527","https://openalex.org/W1999404678","https://openalex.org/W2006290495","https://openalex.org/W2009404076","https://openalex.org/W2030289208","https://openalex.org/W2030621944","https://openalex.org/W2036456126","https://openalex.org/W2037444377","https://openalex.org/W2041391522","https://openalex.org/W2067258168","https://openalex.org/W2075320162","https://openalex.org/W2085802860","https://openalex.org/W2095879381","https://openalex.org/W2096647099","https://openalex.org/W2096959765","https://openalex.org/W2098769462","https://openalex.org/W2099628841","https://openalex.org/W2100080086","https://openalex.org/W2103568877","https://openalex.org/W2103614420","https://openalex.org/W2106462936","https://openalex.org/W2106982820","https://openalex.org/W2114001343","https://openalex.org/W2115308068","https://openalex.org/W2116507553","https://openalex.org/W2118978333","https://openalex.org/W2119582819","https://openalex.org/W2124727440","https://openalex.org/W2131779699","https://openalex.org/W2132926880","https://openalex.org/W2132939808","https://openalex.org/W2133218851","https://openalex.org/W2140586694","https://openalex.org/W2142678478","https://openalex.org/W2144988370","https://openalex.org/W2146628513","https://openalex.org/W2147681005","https://openalex.org/W2148143831","https://openalex.org/W2151207086","https://openalex.org/W2151957804","https://openalex.org/W2154379876","https://openalex.org/W2157052506","https://openalex.org/W2162058902","https://openalex.org/W2165410540","https://openalex.org/W2168172687","https://openalex.org/W2170505850","https://openalex.org/W2171649066","https://openalex.org/W2317570828","https://openalex.org/W2326905672","https://openalex.org/W2328946070","https://openalex.org/W2472746071","https://openalex.org/W2491202635","https://openalex.org/W2511835277","https://openalex.org/W2518034873","https://openalex.org/W2532873024","https://openalex.org/W2557229187","https://openalex.org/W2755335466","https://openalex.org/W2763229022","https://openalex.org/W2766848373","https://openalex.org/W2769518858","https://openalex.org/W2792363117","https://openalex.org/W2796664669","https://openalex.org/W2808777650","https://openalex.org/W2891844772","https://openalex.org/W2899303751","https://openalex.org/W2911461034","https://openalex.org/W2951664338","https://openalex.org/W2955704392","https://openalex.org/W2967717440","https://openalex.org/W2967960129","https://openalex.org/W2970416468","https://openalex.org/W2980057552","https://openalex.org/W2980412682","https://openalex.org/W2982586313","https://openalex.org/W2986507481","https://openalex.org/W2988912894","https://openalex.org/W2998216295","https://openalex.org/W3204616723","https://openalex.org/W4235121031","https://openalex.org/W4245947591","https://openalex.org/W4285719527","https://openalex.org/W6802797615","https://openalex.org/W7066667914"],"related_works":["https://openalex.org/W2967136651","https://openalex.org/W2913646003","https://openalex.org/W2033684641","https://openalex.org/W2081632393","https://openalex.org/W2147509954","https://openalex.org/W4389944751","https://openalex.org/W4362597605","https://openalex.org/W1970773045","https://openalex.org/W3151547568","https://openalex.org/W2918944057"],"abstract_inverted_index":{"Riboswitch,":[0],"a":[1,33,40,68,99,145,193],"part":[2],"of":[3,18,26,39,42,207,211,222,232],"regulatory":[4],"mRNA":[5],"(50-250nt":[6],"in":[7,35,67,78,123,148,157],"length),":[8],"has":[9,203],"two":[10],"main":[11,20],"classes:":[12],"aptamer":[13],"and":[14,60,95,119,134,152,175,186,196,215,225],"expression":[15],"platform.":[16],"One":[17],"the":[19,24,37,50,178,205,209],"challenges":[21,210],"raised":[22],"during":[23],"classification":[25,83],"riboswitch":[27,74,82,199],"is":[28,32,242],"imbalanced":[29,87,135,226],"data.":[30],"That":[31],"circumstance":[34],"which":[36,65,228],"records":[38],"sequences":[41,90,136],"one":[43],"group":[44,59],"are":[45,198],"very":[46],"small":[47],"compared":[48],"to":[49,56,76,109,171,191,234],"others.":[51],"Such":[52],"circumstances":[53],"lead":[54],"classifier":[55],"ignore":[57],"minority":[58],"emphasize":[61],"on":[62,117],"majority":[63,212],"ones,":[64],"results":[66,218],"skewed":[69],"classification.":[70],"We":[71],"considered":[72],"sixteen":[73],"families,":[75],"be":[77],"accord":[79],"with":[80],"recent":[81],"work,":[84],"that":[85],"contain":[86],"sequences.":[88],"The":[89,201,238],"were":[91,114,169,189,219],"split":[92],"into":[93],"training":[94],"test":[96],"set":[97],"using":[98],"newly":[100],"developed":[101],"pipeline.":[102],"From":[103],"5460":[104],"k-mers":[105,164],"(k":[106],"value":[107],"1":[108],"6)":[110],"produced,":[111],"156":[112],"features":[113],"calculated":[115],"based":[116],"CfsSubsetEval":[118],"BestFirst":[120],"function":[121,195],"found":[122],"WEKA":[124],"3.8.":[125],"Statistically":[126],"tested":[127],"result":[128],"was":[129],"significantly":[130],"difference":[131,147],"between":[132],"balanced":[133,224],"(p":[137,160],"<":[138,161],"0.05).":[139,162],"Besides,":[140],"each":[141],"algorithm":[142],"also":[143],"showed":[144],"significant":[146],"sensitivity,":[149],"specificity,":[150],"accuracy,":[151],"macro":[153],"F-score":[154],"when":[155],"used":[156],"both":[158,223],"groups":[159],"Several":[163],"clustered":[165],"from":[166],"heat":[167],"map":[168],"discovered":[170,204],"have":[172,192],"biological":[173,194],"functions":[174],"motifs":[176],"at":[177,244],"different":[179],"positions":[180],"like":[181],"interior":[182],"loops,":[183],"terminal":[184],"loops":[185],"helices.":[187],"They":[188],"validated":[190],"some":[197],"motifs.":[200],"analysis":[202,214],"importance":[206],"solving":[208],"bias":[213],"overfitting.":[216],"Presented":[217],"generalized":[220],"evaluation":[221],"models,":[227],"implies":[229],"their":[230],"ability":[231],"classifying,":[233],"classify":[235],"novel":[236],"riboswitches.":[237],"Python":[239],"source":[240],"code":[241],"available":[243],"https://github.com/Seasonsling/riboswitch.":[245]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2021,"cited_by_count":2}],"updated_date":"2026-01-13T01:12:25.745995","created_date":"2025-10-10T00:00:00"}