{"id":"https://openalex.org/W2972265941","doi":"https://doi.org/10.1371/journal.pcbi.1007325","title":"Network trade-offs and homeostasis in Arabidopsis shoot architectures","display_name":"Network trade-offs and homeostasis in Arabidopsis shoot architectures","publication_year":2019,"publication_date":"2019-09-11","ids":{"openalex":"https://openalex.org/W2972265941","doi":"https://doi.org/10.1371/journal.pcbi.1007325","mag":"2972265941","pmid":"https://pubmed.ncbi.nlm.nih.gov/31509526"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pcbi.1007325","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1007325","pdf_url":null,"source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","datacite","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1371/journal.pcbi.1007325","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5082399611","display_name":"Adam Conn","orcid":"https://orcid.org/0000-0002-4988-7314"},"institutions":[{"id":"https://openalex.org/I1307098950","display_name":"Salk Institute for Biological Studies","ror":"https://ror.org/03xez1567","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1307098950"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Adam Conn","raw_affiliation_strings":["Integrative Biology Laboratory, Salk Institute for Biological Studies, La Jolla, California, United States of America"],"raw_orcid":"https://orcid.org/0000-0002-4988-7314","affiliations":[{"raw_affiliation_string":"Integrative Biology Laboratory, Salk Institute for Biological Studies, La Jolla, California, United States of America","institution_ids":["https://openalex.org/I1307098950"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055496693","display_name":"Arjun Chandrasekhar","orcid":"https://orcid.org/0000-0003-2842-2902"},"institutions":[{"id":"https://openalex.org/I1307098950","display_name":"Salk Institute for Biological Studies","ror":"https://ror.org/03xez1567","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1307098950"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Arjun Chandrasekhar","raw_affiliation_strings":["Integrative Biology Laboratory, Salk Institute for Biological Studies, La Jolla, California, United States of America"],"raw_orcid":"https://orcid.org/0000-0003-2842-2902","affiliations":[{"raw_affiliation_string":"Integrative Biology Laboratory, Salk Institute for Biological Studies, La Jolla, California, United States of America","institution_ids":["https://openalex.org/I1307098950"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034500598","display_name":"Martin van Rongen","orcid":"https://orcid.org/0000-0002-1441-367X"},"institutions":[{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]},{"id":"https://openalex.org/I2800011936","display_name":"Sainsbury Laboratory","ror":"https://ror.org/02tdtzx53","country_code":"GB","type":"facility","lineage":["https://openalex.org/I2800011936"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Martin van Rongen","raw_affiliation_strings":["Sainsbury Laboratory, University of Cambridge, Cambridge, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sainsbury Laboratory, University of Cambridge, Cambridge, United Kingdom","institution_ids":["https://openalex.org/I2800011936","https://openalex.org/I241749"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070192659","display_name":"Ottoline Leyser","orcid":"https://orcid.org/0000-0003-2161-3829"},"institutions":[{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]},{"id":"https://openalex.org/I2800011936","display_name":"Sainsbury Laboratory","ror":"https://ror.org/02tdtzx53","country_code":"GB","type":"facility","lineage":["https://openalex.org/I2800011936"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Ottoline Leyser","raw_affiliation_strings":["Sainsbury Laboratory, University of Cambridge, Cambridge, United Kingdom"],"raw_orcid":"https://orcid.org/0000-0003-2161-3829","affiliations":[{"raw_affiliation_string":"Sainsbury Laboratory, University of Cambridge, Cambridge, United Kingdom","institution_ids":["https://openalex.org/I2800011936","https://openalex.org/I241749"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003016098","display_name":"Joanne Chory","orcid":"https://orcid.org/0000-0002-3664-8525"},"institutions":[{"id":"https://openalex.org/I1307098950","display_name":"Salk Institute for Biological Studies","ror":"https://ror.org/03xez1567","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1307098950"]},{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joanne Chory","raw_affiliation_strings":["Howard Hughes Medical Institute and Plant Biology Laboratory, Salk Institute for Biological Studies, La Jolla, California, United States of America"],"raw_orcid":"https://orcid.org/0000-0002-3664-8525","affiliations":[{"raw_affiliation_string":"Howard Hughes Medical Institute and Plant Biology Laboratory, Salk Institute for Biological Studies, La Jolla, California, United States of America","institution_ids":["https://openalex.org/I1307098950","https://openalex.org/I1344073410"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5060581759","display_name":"Saket Navlakha","orcid":"https://orcid.org/0000-0002-5505-9718"},"institutions":[{"id":"https://openalex.org/I1307098950","display_name":"Salk Institute for Biological Studies","ror":"https://ror.org/03xez1567","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1307098950"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Saket Navlakha","raw_affiliation_strings":["Integrative Biology Laboratory, Salk Institute for Biological Studies, La Jolla, California, United States of America"],"raw_orcid":"https://orcid.org/0000-0002-5505-9718","affiliations":[{"raw_affiliation_string":"Integrative Biology Laboratory, Salk Institute for Biological Studies, La Jolla, California, United States of America","institution_ids":["https://openalex.org/I1307098950"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5060581759"],"corresponding_institution_ids":["https://openalex.org/I1307098950"],"apc_list":{"value":2655,"currency":"USD","value_usd":2655},"apc_paid":{"value":2655,"currency":"USD","value_usd":2655},"fwci":0.2898,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":{"value":0.74540885,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":95},"biblio":{"volume":"15","issue":"9","first_page":"e1007325","last_page":"e1007325"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10184","display_name":"Plant Molecular Biology Research","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10184","display_name":"Plant Molecular Biology Research","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11927","display_name":"Plant Reproductive Biology","score":0.9934999942779541,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10303","display_name":"Photosynthetic Processes and Mechanisms","score":0.9896000027656555,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/arabidopsis","display_name":"Arabidopsis","score":0.8151577711105347},{"id":"https://openalex.org/keywords/shoot","display_name":"Shoot","score":0.5765165686607361},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.5389149785041809},{"id":"https://openalex.org/keywords/trade-off","display_name":"Trade-off","score":0.48886650800704956},{"id":"https://openalex.org/keywords/prioritization","display_name":"Prioritization","score":0.4851261079311371},{"id":"https://openalex.org/keywords/pareto-principle","display_name":"Pareto principle","score":0.43790990114212036},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.34127241373062134},{"id":"https://openalex.org/keywords/mutant","display_name":"Mutant","score":0.2418457567691803},{"id":"https://openalex.org/keywords/mathematical-optimization","display_name":"Mathematical optimization","score":0.20277321338653564},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.1977013349533081},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.19732633233070374},{"id":"https://openalex.org/keywords/ecology","display_name":"Ecology","score":0.17888414859771729},{"id":"https://openalex.org/keywords/botany","display_name":"Botany","score":0.16871660947799683},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.15212273597717285},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.1471165418624878}],"concepts":[{"id":"https://openalex.org/C2779491563","wikidata":"https://www.wikidata.org/wiki/Q157892","display_name":"Arabidopsis","level":4,"score":0.8151577711105347},{"id":"https://openalex.org/C21410773","wikidata":"https://www.wikidata.org/wiki/Q220869","display_name":"Shoot","level":2,"score":0.5765165686607361},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5389149785041809},{"id":"https://openalex.org/C142985932","wikidata":"https://www.wikidata.org/wiki/Q638123","display_name":"Trade-off","level":2,"score":0.48886650800704956},{"id":"https://openalex.org/C2777615720","wikidata":"https://www.wikidata.org/wiki/Q11888847","display_name":"Prioritization","level":2,"score":0.4851261079311371},{"id":"https://openalex.org/C137635306","wikidata":"https://www.wikidata.org/wiki/Q182667","display_name":"Pareto principle","level":2,"score":0.43790990114212036},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.34127241373062134},{"id":"https://openalex.org/C143065580","wikidata":"https://www.wikidata.org/wiki/Q3285695","display_name":"Mutant","level":3,"score":0.2418457567691803},{"id":"https://openalex.org/C126255220","wikidata":"https://www.wikidata.org/wiki/Q141495","display_name":"Mathematical optimization","level":1,"score":0.20277321338653564},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.1977013349533081},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.19732633233070374},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.17888414859771729},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.16871660947799683},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.15212273597717285},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.1471165418624878},{"id":"https://openalex.org/C539667460","wikidata":"https://www.wikidata.org/wiki/Q2414942","display_name":"Management science","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005838","descriptor_name":"Genotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005838","descriptor_name":"Genotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005838","descriptor_name":"Genotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006706","descriptor_name":"Homeostasis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006706","descriptor_name":"Homeostasis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006706","descriptor_name":"Homeostasis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017343","descriptor_name":"Genes, Plant","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017343","descriptor_name":"Genes, Plant","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017343","descriptor_name":"Genes, Plant","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017360","descriptor_name":"Arabidopsis","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":true},{"descriptor_ui":"D017360","descriptor_name":"Arabidopsis","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":true},{"descriptor_ui":"D017360","descriptor_name":"Arabidopsis","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":true},{"descriptor_ui":"D017360","descriptor_name":"Arabidopsis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D017360","descriptor_name":"Arabidopsis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D017360","descriptor_name":"Arabidopsis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D018515","descriptor_name":"Plant Leaves","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":false},{"descriptor_ui":"D018515","descriptor_name":"Plant Leaves","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":false},{"descriptor_ui":"D018515","descriptor_name":"Plant Leaves","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":false},{"descriptor_ui":"D018515","descriptor_name":"Plant Leaves","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018515","descriptor_name":"Plant Leaves","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018515","descriptor_name":"Plant Leaves","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018520","descriptor_name":"Plant Shoots","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":true},{"descriptor_ui":"D018520","descriptor_name":"Plant Shoots","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":true},{"descriptor_ui":"D018520","descriptor_name":"Plant Shoots","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":true},{"descriptor_ui":"D018520","descriptor_name":"Plant Shoots","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D018520","descriptor_name":"Plant Shoots","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D018520","descriptor_name":"Plant Shoots","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":9,"locations":[{"id":"doi:10.1371/journal.pcbi.1007325","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1007325","pdf_url":null,"source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},{"id":"pmid:31509526","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31509526","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS computational biology","raw_type":null},{"id":"pmh:oai:repository.cshl.edu:38641","is_oa":false,"landing_page_url":null,"pdf_url":null,"source":{"id":"https://openalex.org/S4306402288","display_name":"Cold Spring Harbor Laboratory Institutional Repository (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"PeerReviewed"},{"id":"pmh:oai:RePEc:plo:pcbi00:1007325","is_oa":false,"landing_page_url":"https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1007325","pdf_url":null,"source":{"id":"https://openalex.org/S4306401271","display_name":"RePEc: Research Papers in Economics","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I77793887","host_organization_name":"Federal Reserve Bank of St. Louis","host_organization_lineage":["https://openalex.org/I77793887"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"},{"id":"pmh:oai:doaj.org/article:2250534681594b11a4e5000e4cea414e","is_oa":true,"landing_page_url":"https://doaj.org/article/2250534681594b11a4e5000e4cea414e","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Computational Biology, Vol 15, Iss 9, p e1007325 (2019)","raw_type":"article"},{"id":"pmh:oai:europepmc.org:5712602","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6738579","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:figshare.com:article/9806087","is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/Network_trade-offs_and_homeostasis_in_i_Arabidopsis_i_shoot_architectures/9806087","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"},{"id":"pmh:oai:www.repository.cam.ac.uk:1810/296343","is_oa":false,"landing_page_url":"https://www.repository.cam.ac.uk/handle/1810/296343","pdf_url":null,"source":{"id":"https://openalex.org/S4306401777","display_name":"Apollo (University of Cambridge)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I241749","host_organization_name":"University of Cambridge","host_organization_lineage":["https://openalex.org/I241749"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"},{"id":"doi:10.17863/cam.43389","is_oa":true,"landing_page_url":"https://doi.org/10.17863/cam.43389","pdf_url":null,"source":{"id":"https://openalex.org/S7407050737","display_name":"Apollo","issn_l":null,"issn":[],"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":null,"raw_source_name":null,"raw_type":"article-journal"}],"best_oa_location":{"id":"doi:10.1371/journal.pcbi.1007325","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1007325","pdf_url":null,"source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G13680729","display_name":null,"funder_award_id":"1R01DC017695","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G3846332093","display_name":null,"funder_award_id":"GAT3272C","funder_id":"https://openalex.org/F4320320033","funder_display_name":"Gatsby Charitable Foundation"},{"id":"https://openalex.org/G5170478148","display_name":null,"funder_award_id":"5R35GM122604","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G559598136","display_name":null,"funder_award_id":"CAREER DBI-1846554","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G6671297155","display_name":null,"funder_award_id":"CAREER","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G8894620280","display_name":null,"funder_award_id":"DBI-1846554","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320306082","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90"},{"id":"https://openalex.org/F4320306148","display_name":"Pew Charitable Trusts","ror":"https://ror.org/02xhk2825"},{"id":"https://openalex.org/F4320320033","display_name":"Gatsby Charitable Foundation","ror":"https://ror.org/0290hax27"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":69,"referenced_works":["https://openalex.org/W1551468003","https://openalex.org/W1551691749","https://openalex.org/W1564170918","https://openalex.org/W1781224937","https://openalex.org/W1966076168","https://openalex.org/W1978285405","https://openalex.org/W1980705347","https://openalex.org/W1986764159","https://openalex.org/W1998207892","https://openalex.org/W1999230569","https://openalex.org/W1999717088","https://openalex.org/W2000902397","https://openalex.org/W2003728368","https://openalex.org/W2008620264","https://openalex.org/W2010025771","https://openalex.org/W2012097350","https://openalex.org/W2015516003","https://openalex.org/W2015984098","https://openalex.org/W2019525949","https://openalex.org/W2021272950","https://openalex.org/W2029437526","https://openalex.org/W2033098267","https://openalex.org/W2042859590","https://openalex.org/W2057199020","https://openalex.org/W2062316858","https://openalex.org/W2062612066","https://openalex.org/W2071642624","https://openalex.org/W2082725264","https://openalex.org/W2091717318","https://openalex.org/W2095614097","https://openalex.org/W2095867549","https://openalex.org/W2096831779","https://openalex.org/W2107803280","https://openalex.org/W2114511908","https://openalex.org/W2115896557","https://openalex.org/W2118566334","https://openalex.org/W2122102835","https://openalex.org/W2122715485","https://openalex.org/W2126957429","https://openalex.org/W2132614391","https://openalex.org/W2132624219","https://openalex.org/W2137709522","https://openalex.org/W2138171485","https://openalex.org/W2140019714","https://openalex.org/W2144799277","https://openalex.org/W2152506161","https://openalex.org/W2154524337","https://openalex.org/W2157622854","https://openalex.org/W2158298463","https://openalex.org/W2162856247","https://openalex.org/W2164010802","https://openalex.org/W2167219240","https://openalex.org/W2167671547","https://openalex.org/W2291901236","https://openalex.org/W2340740725","https://openalex.org/W2405029591","https://openalex.org/W2419574648","https://openalex.org/W2468141424","https://openalex.org/W2529429932","https://openalex.org/W2550495115","https://openalex.org/W2729230925","https://openalex.org/W2738561053","https://openalex.org/W2749494645","https://openalex.org/W2768721118","https://openalex.org/W2791878475","https://openalex.org/W2890921046","https://openalex.org/W2964287254","https://openalex.org/W3192543836","https://openalex.org/W7073639661"],"related_works":["https://openalex.org/W2809290511","https://openalex.org/W2070215364","https://openalex.org/W2028592543","https://openalex.org/W1991890472","https://openalex.org/W2157586448","https://openalex.org/W2117338545","https://openalex.org/W150704235","https://openalex.org/W2587188970","https://openalex.org/W2901609440","https://openalex.org/W2972265941"],"abstract_inverted_index":{"Understanding":[0],"the":[1,76,91,97,114],"optimization":[2,166],"objectives":[3],"that":[4,37,53,61,85,102,133,144,175],"shape":[5],"shoot":[6,23,55,170],"architectures":[7,40,56,171],"remains":[8],"a":[9,34,58,137,141,155,162],"critical":[10],"problem":[11],"in":[12,68,74,147,154],"plant":[13,121,185],"biology.":[14],"Here,":[15],"we":[16,32,47,79,100],"performed":[17],"3D":[18],"scanning":[19],"of":[20,83,113,125,140],"152":[21],"Arabidopsis":[22,54],"architectures,":[24],"including":[25],"wildtype":[26],"and":[27,31,71,143,172,187],"10":[28],"mutant":[29],"strains,":[30],"uncovered":[33],"design":[35],"principle":[36],"describes":[38],"how":[39],"make":[41],"trade-offs":[42,167,177],"between":[43],"competing":[44],"objectives.":[45],"First,":[46],"used":[48],"graph-theoretic":[49],"analysis":[50],"to":[51,89,118,164],"show":[52,101],"strike":[57],"Pareto":[59],"optimal":[60],"can":[62,86,178],"be":[63,87,150,179],"captured":[64],"as":[65],"maximizing":[66],"performance":[67],"transporting":[69],"nutrients":[70],"minimizing":[72],"costs":[73],"building":[75],"architecture.":[77],"Second,":[78],"identify":[80],"small":[81],"sets":[82],"genes":[84],"mutated":[88],"shift":[90],"weight":[92,105],"prioritizing":[93],"one":[94],"objective":[95],"over":[96],"other.":[98],"Third,":[99],"this":[103,134],"prioritization":[104],"feature":[106,135],"is":[107,136],"significantly":[108],"less":[109],"variable":[110],"across":[111],"replicates":[112],"same":[115],"genotype":[116],"compared":[117],"other":[119],"common":[120],"traits":[122],"(e.g.,":[123],"number":[124],"rosette":[126],"leaves,":[127],"total":[128],"volume":[129],"occupied).":[130],"This":[131],"suggests":[132],"robust":[138],"descriptor":[139],"genotype,":[142],"local":[145],"variability":[146],"structure":[148],"may":[149,183],"compensated":[151],"for":[152],"globally":[153],"homeostatic":[156],"manner.":[157],"Overall,":[158],"our":[159],"work":[160],"provides":[161,173],"framework":[163],"understand":[165],"made":[168],"by":[169],"evidence":[174],"these":[176],"modified":[180],"genetically,":[181],"which":[182],"aid":[184],"breeding":[186],"selection":[188],"efforts.":[189]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2021,"cited_by_count":1}],"updated_date":"2026-05-06T08:25:59.206177","created_date":"2025-10-10T00:00:00"}