{"id":"https://openalex.org/W2950797393","doi":"https://doi.org/10.1371/journal.pcbi.1006646","title":"Epithelial stratification shapes infection dynamics","display_name":"Epithelial stratification shapes infection dynamics","publication_year":2019,"publication_date":"2019-01-23","ids":{"openalex":"https://openalex.org/W2950797393","doi":"https://doi.org/10.1371/journal.pcbi.1006646","mag":"2950797393","pmid":"https://pubmed.ncbi.nlm.nih.gov/30673699"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pcbi.1006646","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1006646","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1006646&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1006646&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5090400029","display_name":"Carmen L\u00eda Murall","orcid":"https://orcid.org/0000-0002-1543-4501"},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I251321805","display_name":"Agropolis International","ror":"https://ror.org/00txxwv34","country_code":"FR","type":"other","lineage":["https://openalex.org/I251321805"]},{"id":"https://openalex.org/I4210087127","display_name":"Maladies Infectieuses et Vecteurs: \u00c9cologie, G\u00e9n\u00e9tique, \u00c9volution et Contr\u00f4le","ror":"https://ror.org/00357kh21","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I1294671590","https://openalex.org/I1294671590","https://openalex.org/I1327553481","https://openalex.org/I154202486","https://openalex.org/I19894307","https://openalex.org/I2799535048","https://openalex.org/I2802818602","https://openalex.org/I4210087127","https://openalex.org/I4210088668","https://openalex.org/I4210088668","https://openalex.org/I4210090127","https://openalex.org/I4210107625","https://openalex.org/I4210113730","https://openalex.org/I4210131494","https://openalex.org/I4210166444","https://openalex.org/I4405257220"]},{"id":"https://openalex.org/I4210166444","display_name":"Institut de Recherche pour le D\u00e9veloppement","ror":"https://ror.org/05q3vnk25","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590","https://openalex.org/I1327553481","https://openalex.org/I154202486","https://openalex.org/I2799535048","https://openalex.org/I2802818602","https://openalex.org/I4210088668","https://openalex.org/I4210090127","https://openalex.org/I4210113730","https://openalex.org/I4210131494","https://openalex.org/I4210166444","https://openalex.org/I4405257220"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Carmen L\u00eda Murall","raw_affiliation_strings":["Laboratoire MIVEGEC (UMR CNRS 5290, IRD, UM), Montpellier, France","MIVEGEC - Maladies infectieuses et vecteurs : \u00e9cologie, g\u00e9n\u00e9tique, \u00e9volution et contr\u00f4le (911 Avenue Agropolis BP 64501 34394 Montpellier cedex 5 - France)"],"affiliations":[{"raw_affiliation_string":"Laboratoire MIVEGEC (UMR CNRS 5290, IRD, UM), Montpellier, France","institution_ids":["https://openalex.org/I4210087127","https://openalex.org/I4210166444","https://openalex.org/I1294671590"]},{"raw_affiliation_string":"MIVEGEC - Maladies infectieuses et vecteurs : \u00e9cologie, g\u00e9n\u00e9tique, \u00e9volution et contr\u00f4le (911 Avenue Agropolis BP 64501 34394 Montpellier cedex 5 - France)","institution_ids":["https://openalex.org/I4210087127","https://openalex.org/I251321805"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073764581","display_name":"Robert Jackson","orcid":"https://orcid.org/0000-0001-9898-5546"},"institutions":[{"id":"https://openalex.org/I4210100115","display_name":"Thunder Bay Regional Research Institute","ror":"https://ror.org/013kbs677","country_code":"CA","type":"facility","lineage":["https://openalex.org/I4210100115"]},{"id":"https://openalex.org/I72541430","display_name":"Lakehead University","ror":"https://ror.org/023p7mg82","country_code":"CA","type":"education","lineage":["https://openalex.org/I72541430"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Robert Jackson","raw_affiliation_strings":["Biotechnology Program, Lakehead University, Thunder Bay, Ontario, Canada","Probe Development and Biomarker Exploration, Thunder Bay Regional Health Research Institute, Thunder Bay, Ontario, Canada","Probe Development and Biomarker Exploration (Thunder Bay Regional Health Research Institute\r\n980 Oliver Road,\r\nThunder Bay, Ontario\r\nP7B 6V4 - Canada)"],"affiliations":[{"raw_affiliation_string":"Biotechnology Program, Lakehead University, Thunder Bay, Ontario, Canada","institution_ids":["https://openalex.org/I72541430"]},{"raw_affiliation_string":"Probe Development and Biomarker Exploration, Thunder Bay Regional Health Research Institute, Thunder Bay, Ontario, Canada","institution_ids":["https://openalex.org/I4210100115"]},{"raw_affiliation_string":"Probe Development and Biomarker Exploration (Thunder Bay Regional Health Research Institute\r\n980 Oliver Road,\r\nThunder Bay, Ontario\r\nP7B 6V4 - Canada)","institution_ids":["https://openalex.org/I4210100115"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082657664","display_name":"Ingeborg Zehbe","orcid":"https://orcid.org/0000-0001-8192-1837"},"institutions":[{"id":"https://openalex.org/I4210100115","display_name":"Thunder Bay Regional Research Institute","ror":"https://ror.org/013kbs677","country_code":"CA","type":"facility","lineage":["https://openalex.org/I4210100115"]},{"id":"https://openalex.org/I72541430","display_name":"Lakehead University","ror":"https://ror.org/023p7mg82","country_code":"CA","type":"education","lineage":["https://openalex.org/I72541430"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Ingeborg Zehbe","raw_affiliation_strings":["Department of Biology, Lakehead University, Thunder Bay, Ontario, Canada","Probe Development and Biomarker Exploration, Thunder Bay Regional Health Research Institute, Thunder Bay, Ontario, Canada","Department of Biology (Canada)","Thunder Bay Regional Research Institute (Thunder Bay, Ontario - Canada)"],"affiliations":[{"raw_affiliation_string":"Department of Biology, Lakehead University, Thunder Bay, Ontario, Canada","institution_ids":["https://openalex.org/I72541430"]},{"raw_affiliation_string":"Probe Development and Biomarker Exploration, Thunder Bay Regional Health Research Institute, Thunder Bay, Ontario, Canada","institution_ids":["https://openalex.org/I4210100115"]},{"raw_affiliation_string":"Department of Biology (Canada)","institution_ids":[]},{"raw_affiliation_string":"Thunder Bay Regional Research Institute (Thunder Bay, Ontario - Canada)","institution_ids":["https://openalex.org/I4210100115"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069196098","display_name":"Nathalie Boulle","orcid":"https://orcid.org/0000-0002-0990-4722"},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I19894307","display_name":"Universit\u00e9 de Montpellier","ror":"https://ror.org/051escj72","country_code":"FR","type":"education","lineage":["https://openalex.org/I19894307"]},{"id":"https://openalex.org/I4210147545","display_name":"H\u00f4pital Arnaud de Villeneuve","ror":"https://ror.org/04m6sq715","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210093292","https://openalex.org/I4210147545"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Nathalie Boulle","raw_affiliation_strings":["Pathogenesis and Control of Chronic Infections, INSERM, EFS, Universit\u00e9 de Montpellier, Montpellier, France","Pathog\u00e9n\u00e8se et contr\u00f4le des infections chroniques (PCCI) (H\u00f4pital Arnaud de Villeneuve - 371 avenue Doyen Gaston Giraud 34295 Cedex 5 Montpellier. - France)"],"affiliations":[{"raw_affiliation_string":"Pathogenesis and Control of Chronic Infections, INSERM, EFS, Universit\u00e9 de Montpellier, Montpellier, France","institution_ids":["https://openalex.org/I19894307","https://openalex.org/I154526488"]},{"raw_affiliation_string":"Pathog\u00e9n\u00e8se et contr\u00f4le des infections chroniques (PCCI) (H\u00f4pital Arnaud de Villeneuve - 371 avenue Doyen Gaston Giraud 34295 Cedex 5 Montpellier. - France)","institution_ids":["https://openalex.org/I4210147545"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015062515","display_name":"Michel Segondy","orcid":"https://orcid.org/0000-0003-3736-5663"},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I19894307","display_name":"Universit\u00e9 de Montpellier","ror":"https://ror.org/051escj72","country_code":"FR","type":"education","lineage":["https://openalex.org/I19894307"]},{"id":"https://openalex.org/I4210147545","display_name":"H\u00f4pital Arnaud de Villeneuve","ror":"https://ror.org/04m6sq715","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210093292","https://openalex.org/I4210147545"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Michel Segondy","raw_affiliation_strings":["Pathogenesis and Control of Chronic Infections, INSERM, EFS, Universit\u00e9 de Montpellier, Montpellier, France","Pathog\u00e9n\u00e8se et contr\u00f4le des infections chroniques (PCCI) (H\u00f4pital Arnaud de Villeneuve - 371 avenue Doyen Gaston Giraud 34295 Cedex 5 Montpellier. - France)"],"affiliations":[{"raw_affiliation_string":"Pathogenesis and Control of Chronic Infections, INSERM, EFS, Universit\u00e9 de Montpellier, Montpellier, France","institution_ids":["https://openalex.org/I19894307","https://openalex.org/I154526488"]},{"raw_affiliation_string":"Pathog\u00e9n\u00e8se et contr\u00f4le des infections chroniques (PCCI) (H\u00f4pital Arnaud de Villeneuve - 371 avenue Doyen Gaston Giraud 34295 Cedex 5 Montpellier. - France)","institution_ids":["https://openalex.org/I4210147545"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5083653654","display_name":"Samuel Alizon","orcid":"https://orcid.org/0000-0002-0779-9543"},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210087127","display_name":"Maladies Infectieuses et Vecteurs: \u00c9cologie, G\u00e9n\u00e9tique, \u00c9volution et Contr\u00f4le","ror":"https://ror.org/00357kh21","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I1294671590","https://openalex.org/I1294671590","https://openalex.org/I1327553481","https://openalex.org/I154202486","https://openalex.org/I19894307","https://openalex.org/I2799535048","https://openalex.org/I2802818602","https://openalex.org/I4210087127","https://openalex.org/I4210088668","https://openalex.org/I4210088668","https://openalex.org/I4210090127","https://openalex.org/I4210107625","https://openalex.org/I4210113730","https://openalex.org/I4210131494","https://openalex.org/I4210166444","https://openalex.org/I4405257220"]},{"id":"https://openalex.org/I4210113621","display_name":"Centre Interdisciplinaire de Recherche en Biologie","ror":"https://ror.org/01mvzn566","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I187986737","https://openalex.org/I4210096427","https://openalex.org/I4210113621"]},{"id":"https://openalex.org/I4210166444","display_name":"Institut de Recherche pour le D\u00e9veloppement","ror":"https://ror.org/05q3vnk25","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590","https://openalex.org/I1327553481","https://openalex.org/I154202486","https://openalex.org/I2799535048","https://openalex.org/I2802818602","https://openalex.org/I4210088668","https://openalex.org/I4210090127","https://openalex.org/I4210113730","https://openalex.org/I4210131494","https://openalex.org/I4210166444","https://openalex.org/I4405257220"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Samuel Alizon","raw_affiliation_strings":["Laboratoire MIVEGEC (UMR CNRS 5290, IRD, UM), Montpellier, France","MIVEGEC-ETE - Evolution Th\u00e9orique et Exp\u00e9rimentale (France)","CIRB - Centre interdisciplinaire de recherche en biologie (11 place Marcellin Berthelot 75005 Paris - France)"],"affiliations":[{"raw_affiliation_string":"Laboratoire MIVEGEC (UMR CNRS 5290, IRD, UM), Montpellier, France","institution_ids":["https://openalex.org/I4210087127","https://openalex.org/I4210166444","https://openalex.org/I1294671590"]},{"raw_affiliation_string":"MIVEGEC-ETE - Evolution Th\u00e9orique et Exp\u00e9rimentale (France)","institution_ids":["https://openalex.org/I4210087127"]},{"raw_affiliation_string":"CIRB - Centre interdisciplinaire de recherche en biologie (11 place Marcellin Berthelot 75005 Paris - France)","institution_ids":["https://openalex.org/I4210113621"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5090400029"],"corresponding_institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I251321805","https://openalex.org/I4210087127","https://openalex.org/I4210166444"],"apc_list":{"value":2655,"currency":"USD","value_usd":2655},"apc_paid":{"value":2655,"currency":"USD","value_usd":2655},"fwci":1.5972,"has_fulltext":true,"cited_by_count":18,"citation_normalized_percentile":{"value":0.83200954,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"15","issue":"1","first_page":"e1006646","last_page":"e1006646"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10146","display_name":"Cervical Cancer and HPV Research","score":0.9973000288009644,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10146","display_name":"Cervical Cancer and HPV Research","score":0.9973000288009644,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10428","display_name":"Reproductive tract infections research","score":0.9950000047683716,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10837","display_name":"Dermatology and Skin Diseases","score":0.9296000003814697,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chlamydia-trachomatis","display_name":"Chlamydia trachomatis","score":0.68499356508255},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.6783716678619385},{"id":"https://openalex.org/keywords/pathogen","display_name":"Pathogen","score":0.648072361946106},{"id":"https://openalex.org/keywords/mucus","display_name":"Mucus","score":0.6355299949645996},{"id":"https://openalex.org/keywords/sexually-transmitted-disease","display_name":"Sexually transmitted disease","score":0.45014315843582153},{"id":"https://openalex.org/keywords/immunology","display_name":"Immunology","score":0.43578311800956726},{"id":"https://openalex.org/keywords/chlamydia","display_name":"Chlamydia","score":0.42924854159355164},{"id":"https://openalex.org/keywords/chlamydia-trachomatis-infection","display_name":"Chlamydia trachomatis infection","score":0.41499772667884827},{"id":"https://openalex.org/keywords/microbiology","display_name":"Microbiology","score":0.3803408145904541},{"id":"https://openalex.org/keywords/virology","display_name":"Virology","score":0.3321426510810852},{"id":"https://openalex.org/keywords/ecology","display_name":"Ecology","score":0.3020172119140625},{"id":"https://openalex.org/keywords/human-immunodeficiency-virus","display_name":"Human immunodeficiency virus (HIV)","score":0.2748411297798157}],"concepts":[{"id":"https://openalex.org/C2777391075","wikidata":"https://www.wikidata.org/wiki/Q131065","display_name":"Chlamydia trachomatis","level":2,"score":0.68499356508255},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6783716678619385},{"id":"https://openalex.org/C2776460866","wikidata":"https://www.wikidata.org/wiki/Q170065","display_name":"Pathogen","level":2,"score":0.648072361946106},{"id":"https://openalex.org/C2777312293","wikidata":"https://www.wikidata.org/wiki/Q3649349","display_name":"Mucus","level":2,"score":0.6355299949645996},{"id":"https://openalex.org/C2909760446","wikidata":"https://www.wikidata.org/wiki/Q12198","display_name":"Sexually transmitted disease","level":4,"score":0.45014315843582153},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.43578311800956726},{"id":"https://openalex.org/C2780122209","wikidata":"https://www.wikidata.org/wiki/Q153356","display_name":"Chlamydia","level":2,"score":0.42924854159355164},{"id":"https://openalex.org/C2909759153","wikidata":"https://www.wikidata.org/wiki/Q153356","display_name":"Chlamydia trachomatis infection","level":3,"score":0.41499772667884827},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.3803408145904541},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.3321426510810852},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.3020172119140625},{"id":"https://openalex.org/C3013748606","wikidata":"https://www.wikidata.org/wiki/Q15787","display_name":"Human immunodeficiency virus (HIV)","level":2,"score":0.2748411297798157},{"id":"https://openalex.org/C2776983459","wikidata":"https://www.wikidata.org/wiki/Q41083","display_name":"Syphilis","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D002690","descriptor_name":"Chlamydia Infections","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D002690","descriptor_name":"Chlamydia Infections","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D002690","descriptor_name":"Chlamydia Infections","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D002690","descriptor_name":"Chlamydia Infections","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D002690","descriptor_name":"Chlamydia Infections","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D002690","descriptor_name":"Chlamydia Infections","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D002692","descriptor_name":"Chlamydia trachomatis","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D002692","descriptor_name":"Chlamydia trachomatis","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D002692","descriptor_name":"Chlamydia trachomatis","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D002692","descriptor_name":"Chlamydia trachomatis","qualifier_ui":"Q000472","qualifier_name":"pathogenicity","is_major_topic":false},{"descriptor_ui":"D002692","descriptor_name":"Chlamydia trachomatis","qualifier_ui":"Q000472","qualifier_name":"pathogenicity","is_major_topic":false},{"descriptor_ui":"D002692","descriptor_name":"Chlamydia trachomatis","qualifier_ui":"Q000472","qualifier_name":"pathogenicity","is_major_topic":false},{"descriptor_ui":"D004848","descriptor_name":"Epithelium","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D004848","descriptor_name":"Epithelium","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D004848","descriptor_name":"Epithelium","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D004848","descriptor_name":"Epithelium","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D004848","descriptor_name":"Epithelium","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D004848","descriptor_name":"Epithelium","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D004848","descriptor_name":"Epithelium","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D004848","descriptor_name":"Epithelium","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D004848","descriptor_name":"Epithelium","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D004848","descriptor_name":"Epithelium","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D004848","descriptor_name":"Epithelium","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D004848","descriptor_name":"Epithelium","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014621","descriptor_name":"Vagina","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D014621","descriptor_name":"Vagina","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D014621","descriptor_name":"Vagina","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D014621","descriptor_name":"Vagina","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D014621","descriptor_name":"Vagina","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D014621","descriptor_name":"Vagina","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D018929","descriptor_name":"Cell Culture Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018929","descriptor_name":"Cell Culture Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018929","descriptor_name":"Cell Culture Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D027383","descriptor_name":"Papillomaviridae","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D027383","descriptor_name":"Papillomaviridae","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D027383","descriptor_name":"Papillomaviridae","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D027383","descriptor_name":"Papillomaviridae","qualifier_ui":"Q000472","qualifier_name":"pathogenicity","is_major_topic":false},{"descriptor_ui":"D027383","descriptor_name":"Papillomaviridae","qualifier_ui":"Q000472","qualifier_name":"pathogenicity","is_major_topic":false},{"descriptor_ui":"D027383","descriptor_name":"Papillomaviridae","qualifier_ui":"Q000472","qualifier_name":"pathogenicity","is_major_topic":false},{"descriptor_ui":"D030361","descriptor_name":"Papillomavirus Infections","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D030361","descriptor_name":"Papillomavirus Infections","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D030361","descriptor_name":"Papillomavirus Infections","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D030361","descriptor_name":"Papillomavirus Infections","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D030361","descriptor_name":"Papillomavirus Infections","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D030361","descriptor_name":"Papillomavirus Infections","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D054884","descriptor_name":"Host-Pathogen Interactions","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D054884","descriptor_name":"Host-Pathogen Interactions","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D054884","descriptor_name":"Host-Pathogen Interactions","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false}],"locations_count":7,"locations":[{"id":"doi:10.1371/journal.pcbi.1006646","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1006646","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1006646&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},{"id":"pmid:30673699","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30673699","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS computational biology","raw_type":null},{"id":"pmh:oai:HAL:hal-02069914v1","is_oa":true,"landing_page_url":"https://hal.science/hal-02069914","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL (Le Centre pour la Communication Scientifique Directe)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1294671590","host_organization_name":"Centre National de la Recherche Scientifique","host_organization_lineage":["https://openalex.org/I1294671590"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Computational Biology, 2019, 15 (1), pp.e1006646. ⟨10.1371/journal.pcbi.1006646⟩","raw_type":"Journal articles"},{"id":"pmh:oai:doaj.org/article:a5803701cc8943ad83b08aba6e4a4a7f","is_oa":true,"landing_page_url":"https://doaj.org/article/a5803701cc8943ad83b08aba6e4a4a7f","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Computational Biology, Vol 15, Iss 1, p e1006646 (2019)","raw_type":"article"},{"id":"pmh:oai:europepmc.org:5362308","is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC6361466","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:figshare.com:article/7621634","is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/Epithelial_stratification_shapes_infection_dynamics/7621634","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"},{"id":"pmh:oai:pubmedcentral.nih.gov:6361466","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6361466","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Comput Biol","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1371/journal.pcbi.1006646","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1006646","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1006646&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1597412403","display_name":null,"funder_award_id":"RGPIN-","funder_id":"https://openalex.org/F4320334593","funder_display_name":"Natural Sciences and Engineering Research Council of Canada"},{"id":"https://openalex.org/G2054169166","display_name":null,"funder_award_id":"#RGPIN-2015-03855","funder_id":"https://openalex.org/F4320334593","funder_display_name":"Natural Sciences and Engineering Research Council of Canada"},{"id":"https://openalex.org/G2165548363","display_name":null,"funder_award_id":"Canada","funder_id":"https://openalex.org/F4320334593","funder_display_name":"Natural Sciences and Engineering Research Council of Canada"},{"id":"https://openalex.org/G2343759012","display_name":"Are HPV vaccines \u2018evolution-proof\u2019? Multilevel evolutionary ecology of human oncoviruses","funder_award_id":"648963","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G2423046499","display_name":null,"funder_award_id":"#RGPIN-2015","funder_id":"https://openalex.org/F4320334593","funder_display_name":"Natural Sciences and Engineering Research Council of Canada"},{"id":"https://openalex.org/G2826976227","display_name":null,"funder_award_id":"2015-03","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G2862252062","display_name":null,"funder_award_id":"Grant","funder_id":"https://openalex.org/F4320334593","funder_display_name":"Natural Sciences and Engineering Research Council of Canada"},{"id":"https://openalex.org/G3216283581","display_name":null,"funder_award_id":"RGPIN-201","funder_id":"https://openalex.org/F4320334593","funder_display_name":"Natural Sciences and Engineering Research Council of Canada"},{"id":"https://openalex.org/G3715132272","display_name":null,"funder_award_id":"RGPIN-2015-03855","funder_id":"https://openalex.org/F4320321487","funder_display_name":"Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada"},{"id":"https://openalex.org/G3996507645","display_name":null,"funder_award_id":"CGS-D","funder_id":"https://openalex.org/F4320334593","funder_display_name":"Natural Sciences and Engineering Research Council of Canada"},{"id":"https://openalex.org/G4956428346","display_name":null,"funder_award_id":"Horizon 2020 research and innovatio","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G4973929103","display_name":null,"funder_award_id":"funding","funder_id":"https://openalex.org/F4320322892","funder_display_name":"Centre National de la Recherche Scientifique"},{"id":"https://openalex.org/G5019307865","display_name":null,"funder_award_id":"Canada Graduate Scholarship-Doctoral (CGS-D)","funder_id":"https://openalex.org/F4320334593","funder_display_name":"Natural Sciences and Engineering Research Council of Canada"},{"id":"https://openalex.org/G5036817778","display_name":null,"funder_award_id":"European Union's Horizon 2020 research and innov","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G5399556803","display_name":null,"funder_award_id":"This project has received funding from the Europea","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G5464013027","display_name":null,"funder_award_id":"454402-2014","funder_id":"https://openalex.org/F4320321487","funder_display_name":"Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada"},{"id":"https://openalex.org/G560051739","display_name":null,"funder_award_id":"RGPIN-2015","funder_id":"https://openalex.org/F4320334593","funder_display_name":"Natural Sciences and Engineering Research Council of Canada"},{"id":"https://openalex.org/G5668898590","display_name":null,"funder_award_id":"454402-2014","funder_id":"https://openalex.org/F4320334593","funder_display_name":"Natural Sciences and Engineering Research Council of Canada"},{"id":"https://openalex.org/G5881564744","display_name":null,"funder_award_id":"RGPIN-2015-0","funder_id":"https://openalex.org/F4320334593","funder_display_name":"Natural Sciences and Engineering Research Council of Canada"},{"id":"https://openalex.org/G6221715925","display_name":null,"funder_award_id":"RGPIN","funder_id":"https://openalex.org/F4320334593","funder_display_name":"Natural Sciences and Engineering Research Council of Canada"},{"id":"https://openalex.org/G6540135544","display_name":null,"funder_award_id":"RGPIN-2015-03855","funder_id":"https://openalex.org/F4320334593","funder_display_name":"Natural Sciences and Engineering Research Council of Canada"},{"id":"https://openalex.org/G7089305364","display_name":null,"funder_award_id":"Doctoral","funder_id":"https://openalex.org/F4320334593","funder_display_name":"Natural Sciences and Engineering Research Council of Canada"},{"id":"https://openalex.org/G8051717526","display_name":null,"funder_award_id":"Grant","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G8284766523","display_name":null,"funder_award_id":"(NSERC)","funder_id":"https://openalex.org/F4320334593","funder_display_name":"Natural Sciences and Engineering Research Council of Canada"},{"id":"https://openalex.org/G8318064016","display_name":null,"funder_award_id":"Horizon","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G8633428685","display_name":null,"funder_award_id":"European Union's Horizon 2020 research and innovat","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G8909571349","display_name":null,"funder_award_id":"#RGPIN-","funder_id":"https://openalex.org/F4320334593","funder_display_name":"Natural Sciences and Engineering Research Council of Canada"},{"id":"https://openalex.org/G8926122883","display_name":null,"funder_award_id":"648963","funder_id":"https://openalex.org/F4320338335","funder_display_name":"H2020 European Research Council"}],"funders":[{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320321487","display_name":"Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada","ror":"https://ror.org/01h531d29"},{"id":"https://openalex.org/F4320322892","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73"},{"id":"https://openalex.org/F4320334593","display_name":"Natural Sciences and Engineering Research Council of Canada","ror":"https://ror.org/01h531d29"},{"id":"https://openalex.org/F4320338335","display_name":"H2020 European Research Council","ror":"https://ror.org/0472cxd90"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2950797393.pdf","grobid_xml":"https://content.openalex.org/works/W2950797393.grobid-xml"},"referenced_works_count":93,"referenced_works":["https://openalex.org/W648877647","https://openalex.org/W1497099219","https://openalex.org/W1500289554","https://openalex.org/W1522687244","https://openalex.org/W1524975252","https://openalex.org/W1593658962","https://openalex.org/W1664192856","https://openalex.org/W1752498633","https://openalex.org/W1827067579","https://openalex.org/W1937133798","https://openalex.org/W1964052073","https://openalex.org/W1966681943","https://openalex.org/W1967658333","https://openalex.org/W1970961755","https://openalex.org/W1973675115","https://openalex.org/W1973697421","https://openalex.org/W1974116805","https://openalex.org/W1974838425","https://openalex.org/W1976111071","https://openalex.org/W1979741424","https://openalex.org/W1979812265","https://openalex.org/W1992363311","https://openalex.org/W1992438887","https://openalex.org/W1997915193","https://openalex.org/W1998288414","https://openalex.org/W1998919574","https://openalex.org/W2001213681","https://openalex.org/W2012718028","https://openalex.org/W2014903591","https://openalex.org/W2018784000","https://openalex.org/W2022593871","https://openalex.org/W2029734559","https://openalex.org/W2031531766","https://openalex.org/W2031808761","https://openalex.org/W2032060490","https://openalex.org/W2034996626","https://openalex.org/W2044651471","https://openalex.org/W2044874413","https://openalex.org/W2048839739","https://openalex.org/W2051521434","https://openalex.org/W2057291925","https://openalex.org/W2060650494","https://openalex.org/W2068965703","https://openalex.org/W2069072974","https://openalex.org/W2071243023","https://openalex.org/W2077542224","https://openalex.org/W2079369104","https://openalex.org/W2081697466","https://openalex.org/W2090396823","https://openalex.org/W2093270774","https://openalex.org/W2099468505","https://openalex.org/W2105458405","https://openalex.org/W2106464597","https://openalex.org/W2122799368","https://openalex.org/W2124312828","https://openalex.org/W2128726449","https://openalex.org/W2130976383","https://openalex.org/W2133595076","https://openalex.org/W2136829296","https://openalex.org/W2139963681","https://openalex.org/W2146881305","https://openalex.org/W2146959560","https://openalex.org/W2147171518","https://openalex.org/W2151949744","https://openalex.org/W2153990966","https://openalex.org/W2165469502","https://openalex.org/W2166022262","https://openalex.org/W2193038194","https://openalex.org/W2313070720","https://openalex.org/W2317845212","https://openalex.org/W2335728124","https://openalex.org/W2335960586","https://openalex.org/W2382210120","https://openalex.org/W2444152384","https://openalex.org/W2461931433","https://openalex.org/W2471996175","https://openalex.org/W2511639854","https://openalex.org/W2513429963","https://openalex.org/W2548316065","https://openalex.org/W2568641556","https://openalex.org/W2595380303","https://openalex.org/W2626963241","https://openalex.org/W2702351303","https://openalex.org/W2757416706","https://openalex.org/W2917419657","https://openalex.org/W3025136633","https://openalex.org/W4300559412","https://openalex.org/W4302331569","https://openalex.org/W4388364567","https://openalex.org/W6621248233","https://openalex.org/W6635461610","https://openalex.org/W6673957574","https://openalex.org/W6720222230"],"related_works":["https://openalex.org/W1983396513","https://openalex.org/W1949477813","https://openalex.org/W2028096858","https://openalex.org/W2401076858","https://openalex.org/W4255454883","https://openalex.org/W2416795476","https://openalex.org/W4210925277","https://openalex.org/W2166285926","https://openalex.org/W2076239467","https://openalex.org/W2442223989"],"abstract_inverted_index":{"Infections":[0],"of":[1,9,133,146],"stratified":[2,35,147],"epithelia":[3],"contribute":[4],"to":[5,41,53,96,103,144],"a":[6,30],"large":[7],"group":[8],"common":[10],"diseases,":[11],"such":[12],"as":[13],"dermatological":[14],"conditions":[15],"and":[16,47,67,92,140],"sexually":[17],"transmitted":[18],"diseases.":[19],"To":[20],"investigate":[21],"how":[22],"epithelial":[23],"structure":[24],"affects":[25],"infection":[26,79,119],"dynamics,":[27],"we":[28,75],"develop":[29],"general":[31],"ecology-inspired":[32],"model":[33,38],"for":[34,127,138],"epithelia.":[36,148],"Our":[37,121],"allows":[39],"us":[40],"simulate":[42],"infections,":[43],"explore":[44],"new":[45,125],"hypotheses":[46,142],"estimate":[48],"parameters":[49],"that":[50,77],"are":[51],"difficult":[52],"measure":[54],"with":[55,87],"tissue":[56,129],"cell":[57],"cultures.":[58],"We":[59],"focus":[60],"on":[61,118],"two":[62],"contrasting":[63],"pathogens:":[64],"Chlamydia":[65],"trachomatis":[66],"Human":[68],"papillomaviruses":[69],"(HPV).":[70],"Using":[71],"cervicovaginal":[72],"parameter":[73],"estimates,":[74],"find":[76],"key":[78],"symptoms":[80],"can":[81],"be":[82,97],"explained":[83],"by":[84],"differential":[85],"interactions":[86],"the":[88],"layers,":[89],"while":[90],"clearance":[91],"pathogen":[93,110],"burden":[94],"appear":[95],"bottom-up":[98],"processes.":[99],"Cell":[100],"protective":[101],"responses":[102],"infections":[104,134,145],"(e.g.":[105],"mucus":[106],"trapping)":[107],"generally":[108],"lowered":[109],"load":[111],"but":[112],"there":[113],"were":[114],"specific":[115],"effects":[116],"based":[117],"strategies.":[120],"modeling":[122],"approach":[123],"opens":[124],"perspectives":[126],"3D":[128],"culture":[130],"experimental":[131],"systems":[132],"and,":[135],"more":[136],"generally,":[137],"developing":[139],"testing":[141],"related":[143]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":1}],"updated_date":"2026-04-16T08:26:57.006410","created_date":"2025-10-10T00:00:00"}