{"id":"https://openalex.org/W2800639417","doi":"https://doi.org/10.1371/journal.pcbi.1006082","title":"Multiscale modelization in a small virus: Mechanism of proton channeling and its role in triggering capsid disassembly","display_name":"Multiscale modelization in a small virus: Mechanism of proton channeling and its role in triggering capsid disassembly","publication_year":2018,"publication_date":"2018-04-16","ids":{"openalex":"https://openalex.org/W2800639417","doi":"https://doi.org/10.1371/journal.pcbi.1006082","mag":"2800639417","pmid":"https://pubmed.ncbi.nlm.nih.gov/29659564"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pcbi.1006082","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1006082","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1006082&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1006082&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5075250592","display_name":"Juan Francisco Viso","orcid":"https://orcid.org/0000-0002-8344-7208"},"institutions":[{"id":"https://openalex.org/I4210094172","display_name":"Instituto de F\u00edsica del Sur","ror":"https://ror.org/00g04a530","country_code":"AR","type":"facility","lineage":["https://openalex.org/I151201029","https://openalex.org/I4210094172","https://openalex.org/I4210123736","https://openalex.org/I4210125789","https://openalex.org/I4387155568","https://openalex.org/I56858762"]},{"id":"https://openalex.org/I4210125789","display_name":"Centro Cient\u00edfico Tecnol\u00f3gico - Bah\u00eda Blanca","ror":"https://ror.org/03efzvv60","country_code":"AR","type":"facility","lineage":["https://openalex.org/I151201029","https://openalex.org/I4210123736","https://openalex.org/I4210125789","https://openalex.org/I4387155568"]},{"id":"https://openalex.org/I56858762","display_name":"Universidad Nacional del Sur","ror":"https://ror.org/028crwz56","country_code":"AR","type":"education","lineage":["https://openalex.org/I56858762"]}],"countries":["AR"],"is_corresponding":false,"raw_author_name":"Juan Francisco Viso","raw_affiliation_strings":["DF-UNS, Grupo de Biof\u00edsica, Instituto de F\u00edsica del Sur (IFISUR, UNS/CONICET), Bah\u00eda Blanca, Argentina","Departamento de F\u00edsica (DF), Universidad Nacional del Sur (UNS), Bah\u00eda Blanca, Argentina"],"raw_orcid":"https://orcid.org/0000-0002-8344-7208","affiliations":[{"raw_affiliation_string":"DF-UNS, Grupo de Biof\u00edsica, Instituto de F\u00edsica del Sur (IFISUR, UNS/CONICET), Bah\u00eda Blanca, Argentina","institution_ids":["https://openalex.org/I4210094172","https://openalex.org/I4210125789"]},{"raw_affiliation_string":"Departamento de F\u00edsica (DF), Universidad Nacional del Sur (UNS), Bah\u00eda Blanca, Argentina","institution_ids":["https://openalex.org/I56858762"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002546174","display_name":"Patricia G. Belelli","orcid":null},"institutions":[{"id":"https://openalex.org/I4210094172","display_name":"Instituto de F\u00edsica del Sur","ror":"https://ror.org/00g04a530","country_code":"AR","type":"facility","lineage":["https://openalex.org/I151201029","https://openalex.org/I4210094172","https://openalex.org/I4210123736","https://openalex.org/I4210125789","https://openalex.org/I4387155568","https://openalex.org/I56858762"]}],"countries":["AR"],"is_corresponding":false,"raw_author_name":"Patricia Belelli","raw_affiliation_strings":["DF-UNS, Grupo de Materiales y Sistemas Catal\u00edticos (GRUMASICA), IFISUR, Bah\u00eda Blanca, Argentina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"DF-UNS, Grupo de Materiales y Sistemas Catal\u00edticos (GRUMASICA), IFISUR, Bah\u00eda Blanca, Argentina","institution_ids":["https://openalex.org/I4210094172"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005916377","display_name":"Mat\u00edas Machado","orcid":"https://orcid.org/0000-0002-9971-4710"},"institutions":[{"id":"https://openalex.org/I4210156231","display_name":"Institut Pasteur de Montevideo","ror":"https://ror.org/04dpm2z73","country_code":"UY","type":"facility","lineage":["https://openalex.org/I4210156231"]}],"countries":["UY"],"is_corresponding":false,"raw_author_name":"Mat\u00edas Machado","raw_affiliation_strings":["Grupo de Simulaciones Biomoleculares, Institut Pasteur de Montevideo, Montevideo, Uruguay"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Grupo de Simulaciones Biomoleculares, Institut Pasteur de Montevideo, Montevideo, Uruguay","institution_ids":["https://openalex.org/I4210156231"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013497733","display_name":"Humberto Gonz\u00e1lez\u2010D\u00edaz","orcid":"https://orcid.org/0000-0002-9392-2797"},"institutions":[{"id":"https://openalex.org/I4210156231","display_name":"Institut Pasteur de Montevideo","ror":"https://ror.org/04dpm2z73","country_code":"UY","type":"facility","lineage":["https://openalex.org/I4210156231"]}],"countries":["UY"],"is_corresponding":false,"raw_author_name":"Humberto Gonz\u00e1lez","raw_affiliation_strings":["Grupo de Simulaciones Biomoleculares, Institut Pasteur de Montevideo, Montevideo, Uruguay"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Grupo de Simulaciones Biomoleculares, Institut Pasteur de Montevideo, Montevideo, Uruguay","institution_ids":["https://openalex.org/I4210156231"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035123082","display_name":"Sergio Pantano","orcid":"https://orcid.org/0000-0001-6435-4543"},"institutions":[{"id":"https://openalex.org/I4210156231","display_name":"Institut Pasteur de Montevideo","ror":"https://ror.org/04dpm2z73","country_code":"UY","type":"facility","lineage":["https://openalex.org/I4210156231"]}],"countries":["UY"],"is_corresponding":false,"raw_author_name":"Sergio Pantano","raw_affiliation_strings":["Grupo de Simulaciones Biomoleculares, Institut Pasteur de Montevideo, Montevideo, Uruguay"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Grupo de Simulaciones Biomoleculares, Institut Pasteur de Montevideo, Montevideo, Uruguay","institution_ids":["https://openalex.org/I4210156231"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038994324","display_name":"Mar\u00eda Julia Amundarain","orcid":"https://orcid.org/0000-0002-0980-5775"},"institutions":[{"id":"https://openalex.org/I4210094172","display_name":"Instituto de F\u00edsica del Sur","ror":"https://ror.org/00g04a530","country_code":"AR","type":"facility","lineage":["https://openalex.org/I151201029","https://openalex.org/I4210094172","https://openalex.org/I4210123736","https://openalex.org/I4210125789","https://openalex.org/I4387155568","https://openalex.org/I56858762"]},{"id":"https://openalex.org/I4210125789","display_name":"Centro Cient\u00edfico Tecnol\u00f3gico - Bah\u00eda Blanca","ror":"https://ror.org/03efzvv60","country_code":"AR","type":"facility","lineage":["https://openalex.org/I151201029","https://openalex.org/I4210123736","https://openalex.org/I4210125789","https://openalex.org/I4387155568"]},{"id":"https://openalex.org/I56858762","display_name":"Universidad Nacional del Sur","ror":"https://ror.org/028crwz56","country_code":"AR","type":"education","lineage":["https://openalex.org/I56858762"]}],"countries":["AR"],"is_corresponding":false,"raw_author_name":"Mar\u00eda Julia Amundarain","raw_affiliation_strings":["DF-UNS, Grupo de Biof\u00edsica, Instituto de F\u00edsica del Sur (IFISUR, UNS/CONICET), Bah\u00eda Blanca, Argentina","Departamento de F\u00edsica (DF), Universidad Nacional del Sur (UNS), Bah\u00eda Blanca, Argentina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"DF-UNS, Grupo de Biof\u00edsica, Instituto de F\u00edsica del Sur (IFISUR, UNS/CONICET), Bah\u00eda Blanca, Argentina","institution_ids":["https://openalex.org/I4210094172","https://openalex.org/I4210125789"]},{"raw_affiliation_string":"Departamento de F\u00edsica (DF), Universidad Nacional del Sur (UNS), Bah\u00eda Blanca, Argentina","institution_ids":["https://openalex.org/I56858762"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091005650","display_name":"Fernando Zamarre\u00f1o","orcid":"https://orcid.org/0000-0002-5022-2010"},"institutions":[{"id":"https://openalex.org/I4210094172","display_name":"Instituto de F\u00edsica del Sur","ror":"https://ror.org/00g04a530","country_code":"AR","type":"facility","lineage":["https://openalex.org/I151201029","https://openalex.org/I4210094172","https://openalex.org/I4210123736","https://openalex.org/I4210125789","https://openalex.org/I4387155568","https://openalex.org/I56858762"]},{"id":"https://openalex.org/I4210125789","display_name":"Centro Cient\u00edfico Tecnol\u00f3gico - Bah\u00eda Blanca","ror":"https://ror.org/03efzvv60","country_code":"AR","type":"facility","lineage":["https://openalex.org/I151201029","https://openalex.org/I4210123736","https://openalex.org/I4210125789","https://openalex.org/I4387155568"]},{"id":"https://openalex.org/I56858762","display_name":"Universidad Nacional del Sur","ror":"https://ror.org/028crwz56","country_code":"AR","type":"education","lineage":["https://openalex.org/I56858762"]}],"countries":["AR"],"is_corresponding":false,"raw_author_name":"Fernando Zamarre\u00f1o","raw_affiliation_strings":["DF-UNS, Grupo de Biof\u00edsica, Instituto de F\u00edsica del Sur (IFISUR, UNS/CONICET), Bah\u00eda Blanca, Argentina","Departamento de F\u00edsica (DF), Universidad Nacional del Sur (UNS), Bah\u00eda Blanca, Argentina"],"raw_orcid":"https://orcid.org/0000-0002-5022-2010","affiliations":[{"raw_affiliation_string":"DF-UNS, Grupo de Biof\u00edsica, Instituto de F\u00edsica del Sur (IFISUR, UNS/CONICET), Bah\u00eda Blanca, Argentina","institution_ids":["https://openalex.org/I4210094172","https://openalex.org/I4210125789"]},{"raw_affiliation_string":"Departamento de F\u00edsica (DF), Universidad Nacional del Sur (UNS), Bah\u00eda Blanca, Argentina","institution_ids":["https://openalex.org/I56858762"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017256754","display_name":"Mar\u00eda M. Branda","orcid":"https://orcid.org/0000-0002-0877-3986"},"institutions":[{"id":"https://openalex.org/I4210094172","display_name":"Instituto de F\u00edsica del Sur","ror":"https://ror.org/00g04a530","country_code":"AR","type":"facility","lineage":["https://openalex.org/I151201029","https://openalex.org/I4210094172","https://openalex.org/I4210123736","https://openalex.org/I4210125789","https://openalex.org/I4387155568","https://openalex.org/I56858762"]},{"id":"https://openalex.org/I56858762","display_name":"Universidad Nacional del Sur","ror":"https://ror.org/028crwz56","country_code":"AR","type":"education","lineage":["https://openalex.org/I56858762"]}],"countries":["AR"],"is_corresponding":false,"raw_author_name":"Maria Marta Branda","raw_affiliation_strings":["DF-UNS, Grupo de Materiales y Sistemas Catal\u00edticos (GRUMASICA), IFISUR, Bah\u00eda Blanca, Argentina","Departamento de F\u00edsica (DF), Universidad Nacional del Sur (UNS), Bah\u00eda Blanca, Argentina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"DF-UNS, Grupo de Materiales y Sistemas Catal\u00edticos (GRUMASICA), IFISUR, Bah\u00eda Blanca, Argentina","institution_ids":["https://openalex.org/I4210094172"]},{"raw_affiliation_string":"Departamento de F\u00edsica (DF), Universidad Nacional del Sur (UNS), Bah\u00eda Blanca, Argentina","institution_ids":["https://openalex.org/I56858762"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101847960","display_name":"Diego M. A. Gu\u00e9rin","orcid":"https://orcid.org/0000-0003-4800-3326"},"institutions":[{"id":"https://openalex.org/I169108374","display_name":"University of the Basque Country","ror":"https://ror.org/000xsnr85","country_code":"ES","type":"education","lineage":["https://openalex.org/I169108374"]},{"id":"https://openalex.org/I4210118072","display_name":"Instituto Biofisika","ror":"https://ror.org/01pf2cj55","country_code":"ES","type":"facility","lineage":["https://openalex.org/I134820265","https://openalex.org/I169108374","https://openalex.org/I4210118072"]}],"countries":["ES"],"is_corresponding":true,"raw_author_name":"Diego M. A. Gu\u00e9rin","raw_affiliation_strings":["Instituto Biofisika (UPV/EHU, CSIC), Department of Biochemistry and Molecular Biology, University of the Basque Country (EHU), Barrio Sarriena S/N, Leioa, Vizcaya, Spain"],"raw_orcid":"https://orcid.org/0000-0003-4800-3326","affiliations":[{"raw_affiliation_string":"Instituto Biofisika (UPV/EHU, CSIC), Department of Biochemistry and Molecular Biology, University of the Basque Country (EHU), Barrio Sarriena S/N, Leioa, Vizcaya, Spain","institution_ids":["https://openalex.org/I169108374","https://openalex.org/I4210118072"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5037491299","display_name":"Marcelo D. Costabel","orcid":"https://orcid.org/0000-0002-8969-7208"},"institutions":[{"id":"https://openalex.org/I4210094172","display_name":"Instituto de F\u00edsica del Sur","ror":"https://ror.org/00g04a530","country_code":"AR","type":"facility","lineage":["https://openalex.org/I151201029","https://openalex.org/I4210094172","https://openalex.org/I4210123736","https://openalex.org/I4210125789","https://openalex.org/I4387155568","https://openalex.org/I56858762"]},{"id":"https://openalex.org/I4210125789","display_name":"Centro Cient\u00edfico Tecnol\u00f3gico - Bah\u00eda Blanca","ror":"https://ror.org/03efzvv60","country_code":"AR","type":"facility","lineage":["https://openalex.org/I151201029","https://openalex.org/I4210123736","https://openalex.org/I4210125789","https://openalex.org/I4387155568"]},{"id":"https://openalex.org/I56858762","display_name":"Universidad Nacional del Sur","ror":"https://ror.org/028crwz56","country_code":"AR","type":"education","lineage":["https://openalex.org/I56858762"]}],"countries":["AR"],"is_corresponding":true,"raw_author_name":"Marcelo D. Costabel","raw_affiliation_strings":["DF-UNS, Grupo de Biof\u00edsica, Instituto de F\u00edsica del Sur (IFISUR, UNS/CONICET), Bah\u00eda Blanca, Argentina","Departamento de F\u00edsica (DF), Universidad Nacional del Sur (UNS), Bah\u00eda Blanca, Argentina"],"raw_orcid":"https://orcid.org/0000-0002-8969-7208","affiliations":[{"raw_affiliation_string":"DF-UNS, Grupo de Biof\u00edsica, Instituto de F\u00edsica del Sur (IFISUR, UNS/CONICET), Bah\u00eda Blanca, Argentina","institution_ids":["https://openalex.org/I4210094172","https://openalex.org/I4210125789"]},{"raw_affiliation_string":"Departamento de F\u00edsica (DF), Universidad Nacional del Sur (UNS), Bah\u00eda Blanca, Argentina","institution_ids":["https://openalex.org/I56858762"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":10,"corresponding_author_ids":["https://openalex.org/A5037491299","https://openalex.org/A5101847960"],"corresponding_institution_ids":["https://openalex.org/I169108374","https://openalex.org/I4210094172","https://openalex.org/I4210118072","https://openalex.org/I4210125789","https://openalex.org/I56858762"],"apc_list":{"value":2655,"currency":"USD","value_usd":2655},"apc_paid":{"value":2655,"currency":"USD","value_usd":2655},"fwci":2.9263,"has_fulltext":true,"cited_by_count":21,"citation_normalized_percentile":{"value":0.90464881,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":98},"biblio":{"volume":"14","issue":"4","first_page":"e1006082","last_page":"e1006082"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11048","display_name":"Bacteriophages and microbial interactions","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2303","display_name":"Ecology"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11048","display_name":"Bacteriophages and microbial interactions","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2303","display_name":"Ecology"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10494","display_name":"Plant Virus Research Studies","score":0.998199999332428,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10976","display_name":"Viral gastroenteritis research and epidemiology","score":0.9977999925613403,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/capsid","display_name":"Capsid","score":0.9764575362205505},{"id":"https://openalex.org/keywords/biophysics","display_name":"Biophysics","score":0.617110013961792},{"id":"https://openalex.org/keywords/icosahedral-symmetry","display_name":"Icosahedral symmetry","score":0.6050362586975098},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.41997548937797546},{"id":"https://openalex.org/keywords/virus","display_name":"Virus","score":0.40134429931640625},{"id":"https://openalex.org/keywords/crystallography","display_name":"Crystallography","score":0.3449639081954956},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.31252020597457886},{"id":"https://openalex.org/keywords/virology","display_name":"Virology","score":0.21296784281730652}],"concepts":[{"id":"https://openalex.org/C202878990","wikidata":"https://www.wikidata.org/wiki/Q830465","display_name":"Capsid","level":3,"score":0.9764575362205505},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.617110013961792},{"id":"https://openalex.org/C113709186","wikidata":"https://www.wikidata.org/wiki/Q5986738","display_name":"Icosahedral symmetry","level":2,"score":0.6050362586975098},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.41997548937797546},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.40134429931640625},{"id":"https://openalex.org/C8010536","wikidata":"https://www.wikidata.org/wiki/Q160398","display_name":"Crystallography","level":1,"score":0.3449639081954956},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.31252020597457886},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.21296784281730652}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002213","descriptor_name":"Capsid","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D002213","descriptor_name":"Capsid","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D002213","descriptor_name":"Capsid","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D002213","descriptor_name":"Capsid","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D002213","descriptor_name":"Capsid","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D002213","descriptor_name":"Capsid","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D006863","descriptor_name":"Hydrogen-Ion Concentration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006863","descriptor_name":"Hydrogen-Ion Concentration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006863","descriptor_name":"Hydrogen-Ion Concentration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007473","descriptor_name":"Ion Channels","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007473","descriptor_name":"Ion Channels","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007473","descriptor_name":"Ion Channels","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011522","descriptor_name":"Protons","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011522","descriptor_name":"Protons","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011522","descriptor_name":"Protons","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019065","descriptor_name":"Virus Assembly","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D019065","descriptor_name":"Virus Assembly","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D019065","descriptor_name":"Virus Assembly","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055672","descriptor_name":"Static Electricity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055672","descriptor_name":"Static Electricity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055672","descriptor_name":"Static Electricity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D056004","descriptor_name":"Molecular Dynamics Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D056004","descriptor_name":"Molecular Dynamics Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D056004","descriptor_name":"Molecular Dynamics Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D056629","descriptor_name":"Dicistroviridae","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D056629","descriptor_name":"Dicistroviridae","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D056629","descriptor_name":"Dicistroviridae","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D056629","descriptor_name":"Dicistroviridae","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D056629","descriptor_name":"Dicistroviridae","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D056629","descriptor_name":"Dicistroviridae","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D056629","descriptor_name":"Dicistroviridae","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D056629","descriptor_name":"Dicistroviridae","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D056629","descriptor_name":"Dicistroviridae","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D057927","descriptor_name":"Hydrophobic and Hydrophilic Interactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057927","descriptor_name":"Hydrophobic and Hydrophilic Interactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057927","descriptor_name":"Hydrophobic and Hydrophilic Interactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":10,"locations":[{"id":"doi:10.1371/journal.pcbi.1006082","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1006082","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1006082&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},{"id":"pmid:29659564","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29659564","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS computational biology","raw_type":null},{"id":"pmh:oai:RePEc:plo:pcbi00:1006082","is_oa":false,"landing_page_url":"https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1006082","pdf_url":null,"source":{"id":"https://openalex.org/S4306401271","display_name":"RePEc: Research Papers in Economics","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I77793887","host_organization_name":"Federal Reserve Bank of St. Louis","host_organization_lineage":["https://openalex.org/I77793887"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"},{"id":"pmh:oai:addi.ehu.es:10810/30191","is_oa":true,"landing_page_url":"http://hdl.handle.net/10810/30191","pdf_url":null,"source":{"id":"https://openalex.org/S4306400469","display_name":"Communities in ADDI (Universidad del Pais Vasco)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210131160","host_organization_name":"Material Physics Center","host_organization_lineage":["https://openalex.org/I4210131160"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:americanae.aecid.es:3895263","is_oa":true,"landing_page_url":"http://americanae.aecid.es/americanae/es/registros/registro.do?tipoRegistro=MTD&idBib=3895263","pdf_url":null,"source":{"id":"https://openalex.org/S4306400786","display_name":"Americanae (AECID Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"reponame:CONICET Digital (CONICET)","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:digital.csic.es:10261/402426","is_oa":true,"landing_page_url":"http://hdl.handle.net/10261/402426","pdf_url":null,"source":{"id":"https://openalex.org/S4306401639","display_name":"DIGITAL.CSIC (Spanish National Research Council (CSIC))","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I134820265","host_organization_name":"Consejo Superior de Investigaciones Cient\u00edficas","host_organization_lineage":["https://openalex.org/I134820265"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"pmh:oai:doaj.org/article:928e61b5fce94148ad69c3ad0f884624","is_oa":true,"landing_page_url":"https://doaj.org/article/928e61b5fce94148ad69c3ad0f884624","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Computational Biology, Vol 14, Iss 4, p e1006082 (2018)","raw_type":"article"},{"id":"pmh:oai:europepmc.org:4863812","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5919690","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:figshare.com:article/6146153","is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/Multiscale_modelization_in_a_small_virus_Mechanism_of_proton_channeling_and_its_role_in_triggering_capsid_disassembly/6146153","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"},{"id":"pmh:oai:ri.conicet.gov.ar:11336/94750","is_oa":true,"landing_page_url":"http://hdl.handle.net/11336/94750","pdf_url":null,"source":{"id":"https://openalex.org/S4306401400","display_name":"Conicet","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210104196","host_organization_name":"Centro Cient\u00edfico Tecnol\u00f3gico - Nordeste","host_organization_lineage":["https://openalex.org/I4210104196"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"reponame:CONICET Digital (CONICET)","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1371/journal.pcbi.1006082","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1006082","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1006082&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Life in Land","id":"https://metadata.un.org/sdg/15","score":0.46000000834465027}],"awards":[{"id":"https://openalex.org/G1950957317","display_name":null,"funder_award_id":"PGI \u2013 UNS N\u00b0 24/F064","funder_id":"https://openalex.org/F4320323402","funder_display_name":"Universidad Nacional del Sur"},{"id":"https://openalex.org/G2096045566","display_name":null,"funder_award_id":"KK-2017/00008","funder_id":"https://openalex.org/F4320321705","funder_display_name":"Eusko Jaurlaritza"},{"id":"https://openalex.org/G2424882271","display_name":null,"funder_award_id":"2016-17","funder_id":"https://openalex.org/F4320322930","funder_display_name":"Ministerio de Ciencia e Innovaci\u00f3n"},{"id":"https://openalex.org/G3908294882","display_name":null,"funder_award_id":"COF 03/11 and SNI","funder_id":"https://openalex.org/F4320310753","funder_display_name":"Agencia Nacional de Investigaci\u00f3n e Innovaci\u00f3n"},{"id":"https://openalex.org/G3962881051","display_name":null,"funder_award_id":"BFU2012-36241","funder_id":"https://openalex.org/F4320322930","funder_display_name":"Ministerio de Ciencia e Innovaci\u00f3n"},{"id":"https://openalex.org/G4000513452","display_name":null,"funder_award_id":"112-2010100949","funder_id":"https://openalex.org/F4320321594","funder_display_name":"Consejo Nacional de Investigaciones Cient\u00edficas y T\u00e9cnicas"},{"id":"https://openalex.org/G4359570771","display_name":null,"funder_award_id":"PIP 112","funder_id":"https://openalex.org/F4320321594","funder_display_name":"Consejo Nacional de Investigaciones Cient\u00edficas y T\u00e9cnicas"},{"id":"https://openalex.org/G4870198231","display_name":null,"funder_award_id":"COF 03/11","funder_id":"https://openalex.org/F4320310753","funder_display_name":"Agencia Nacional de Investigaci\u00f3n e Innovaci\u00f3n"},{"id":"https://openalex.org/G5478084243","display_name":null,"funder_award_id":"PIP 112-2010100949","funder_id":"https://openalex.org/F4320321594","funder_display_name":"Consejo Nacional de Investigaciones Cient\u00edficas y T\u00e9cnicas"},{"id":"https://openalex.org/G6493052913","display_name":null,"funder_award_id":"IT849-13","funder_id":"https://openalex.org/F4320321705","funder_display_name":"Eusko Jaurlaritza"},{"id":"https://openalex.org/G6538315250","display_name":null,"funder_award_id":"Elkartek KK-2017/00008","funder_id":"https://openalex.org/F4320321705","funder_display_name":"Eusko Jaurlaritza"},{"id":"https://openalex.org/G7003424106","display_name":null,"funder_award_id":"PICT 2014","funder_id":"https://openalex.org/F4320334832","funder_display_name":"Agencia Nacional de Promoci\u00f3n Cient\u00edfica y Tecnol\u00f3gica"},{"id":"https://openalex.org/G7200587383","display_name":null,"funder_award_id":"Grupos Consolidados IT849-13","funder_id":"https://openalex.org/F4320321705","funder_display_name":"Eusko Jaurlaritza"},{"id":"https://openalex.org/G7320837138","display_name":null,"funder_award_id":"PGI \u2013 UNS N\u00b0 24/F051","funder_id":"https://openalex.org/F4320323402","funder_display_name":"Universidad Nacional del Sur"},{"id":"https://openalex.org/G7378882120","display_name":null,"funder_award_id":"CONICET","funder_id":"https://openalex.org/F4320334832","funder_display_name":"Agencia Nacional de Promoci\u00f3n Cient\u00edfica y Tecnol\u00f3gica"},{"id":"https://openalex.org/G7596503947","display_name":null,"funder_award_id":"PICT 2010 - N\u00b0 0830","funder_id":"https://openalex.org/F4320334832","funder_display_name":"Agencia Nacional de Promoci\u00f3n Cient\u00edfica y Tecnol\u00f3gica"},{"id":"https://openalex.org/G7696816827","display_name":null,"funder_award_id":"PICT 2010","funder_id":"https://openalex.org/F4320334832","funder_display_name":"Agencia Nacional de Promoci\u00f3n Cient\u00edfica y Tecnol\u00f3gica"},{"id":"https://openalex.org/G849230359","display_name":null,"funder_award_id":"PICT 2014","funder_id":"https://openalex.org/F4320321594","funder_display_name":"Consejo Nacional de Investigaciones Cient\u00edficas y T\u00e9cnicas"},{"id":"https://openalex.org/G8649734004","display_name":null,"funder_award_id":"COF 03/11","funder_id":"https://openalex.org/F4320334832","funder_display_name":"Agencia Nacional de Promoci\u00f3n Cient\u00edfica y Tecnol\u00f3gica"}],"funders":[{"id":"https://openalex.org/F4320309480","display_name":"Nvidia","ror":"https://ror.org/03jdj4y14"},{"id":"https://openalex.org/F4320310753","display_name":"Agencia Nacional de Investigaci\u00f3n e Innovaci\u00f3n","ror":"https://ror.org/03egaj678"},{"id":"https://openalex.org/F4320321594","display_name":"Consejo Nacional de Investigaciones Cient\u00edficas y T\u00e9cnicas","ror":"https://ror.org/03cqe8w59"},{"id":"https://openalex.org/F4320321705","display_name":"Eusko Jaurlaritza","ror":"https://ror.org/00pz2fp31"},{"id":"https://openalex.org/F4320321919","display_name":"Euskal Herriko Unibertsitatea","ror":"https://ror.org/000xsnr85"},{"id":"https://openalex.org/F4320322930","display_name":"Ministerio de Ciencia e Innovaci\u00f3n","ror":"https://ror.org/034900433"},{"id":"https://openalex.org/F4320323402","display_name":"Universidad Nacional del Sur","ror":"https://ror.org/028crwz56"},{"id":"https://openalex.org/F4320325124","display_name":"CYTED Ciencia y Tecnolog\u00eda para el Desarrollo","ror":"https://ror.org/03myqtf56"},{"id":"https://openalex.org/F4320334832","display_name":"Agencia Nacional de Promoci\u00f3n Cient\u00edfica y Tecnol\u00f3gica","ror":"https://ror.org/03stxzb56"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2800639417.pdf","grobid_xml":"https://content.openalex.org/works/W2800639417.grobid-xml"},"referenced_works_count":66,"referenced_works":["https://openalex.org/W1491824558","https://openalex.org/W1514232196","https://openalex.org/W1550061415","https://openalex.org/W1573351573","https://openalex.org/W1967562476","https://openalex.org/W1970955219","https://openalex.org/W1975755749","https://openalex.org/W1982555875","https://openalex.org/W1984396285","https://openalex.org/W1985950029","https://openalex.org/W1993177346","https://openalex.org/W1993858000","https://openalex.org/W1997173539","https://openalex.org/W2001342993","https://openalex.org/W2007558144","https://openalex.org/W2009771578","https://openalex.org/W2010548973","https://openalex.org/W2012134014","https://openalex.org/W2012592738","https://openalex.org/W2021141826","https://openalex.org/W2030217026","https://openalex.org/W2030684958","https://openalex.org/W2031272029","https://openalex.org/W2036914998","https://openalex.org/W2038208367","https://openalex.org/W2040565000","https://openalex.org/W2043901383","https://openalex.org/W2045985602","https://openalex.org/W2061434273","https://openalex.org/W2063079310","https://openalex.org/W2065372326","https://openalex.org/W2067174909","https://openalex.org/W2077973224","https://openalex.org/W2080885412","https://openalex.org/W2099179975","https://openalex.org/W2104129019","https://openalex.org/W2105120291","https://openalex.org/W2111479429","https://openalex.org/W2127522551","https://openalex.org/W2128588803","https://openalex.org/W2140975932","https://openalex.org/W2141273392","https://openalex.org/W2146752617","https://openalex.org/W2149076987","https://openalex.org/W2156008447","https://openalex.org/W2157586119","https://openalex.org/W2159985260","https://openalex.org/W2165120022","https://openalex.org/W2169559165","https://openalex.org/W2171268876","https://openalex.org/W2230728100","https://openalex.org/W2322859143","https://openalex.org/W2331642863","https://openalex.org/W2331727781","https://openalex.org/W2334755164","https://openalex.org/W2416666224","https://openalex.org/W2468070683","https://openalex.org/W2509804221","https://openalex.org/W2517293899","https://openalex.org/W2560350687","https://openalex.org/W2574545442","https://openalex.org/W2751967332","https://openalex.org/W3155437840","https://openalex.org/W4213337030","https://openalex.org/W4252571607","https://openalex.org/W6632902360"],"related_works":["https://openalex.org/W2587076120","https://openalex.org/W2137572138","https://openalex.org/W2968050865","https://openalex.org/W2066534028","https://openalex.org/W2076921277","https://openalex.org/W832774369","https://openalex.org/W2335637493","https://openalex.org/W2033677185","https://openalex.org/W1665067482","https://openalex.org/W1980824864"],"abstract_inverted_index":{"In":[0],"this":[1,26,186],"work,":[2],"we":[3,28,95,172],"assess":[4],"a":[5,34,40,60,69,104,140,163,216],"previously":[6],"advanced":[7],"hypothesis":[8],"that":[9,158,177,196,220],"predicts":[10],"the":[11,17,51,66,83,88,98,101,108,111,115,128,131,137,146,152,159,167,170,191,223],"existence":[12],"of":[13,19,68,75,103,114,169,193,201,218,227],"ion":[14,125],"channels":[15],"in":[16,53,107,127,166,205],"capsid":[18,42,89,138,153,194],"small":[20],"and":[21,49,214,225],"non-enveloped":[22],"icosahedral":[23,229],"viruses.":[24,230],"With":[25],"purpose":[27],"examine":[29],"Triatoma":[30],"Virus":[31],"(TrV)":[32],"as":[33],"case":[35],"study.":[36],"This":[37],"virus":[38,117],"has":[39],"stable":[41],"under":[43],"highly":[44],"acidic":[45],"conditions":[46],"but":[47],"disassembles":[48],"releases":[50],"genome":[52,92],"alkaline":[54],"environments.":[55],"Our":[56,77],"calculations":[57,203],"range":[58],"from":[59],"subtle":[61],"sub-atomic":[62],"proton":[63,160],"interchange":[64],"to":[65,90,135],"dismantling":[67],"large-scale":[70],"system":[71],"representing":[72],"several":[73],"million":[74],"atoms.":[76],"results":[78],"provide":[79],"structure-based":[80],"explanations":[81],"for":[82,97],"three":[84],"roles":[85],"played":[86],"by":[87,123],"enable":[91],"release.":[93,199],"First,":[94],"observe,":[96],"first":[99],"time,":[100],"formation":[102],"hydrophobic":[105],"gate":[106],"cavity":[109],"along":[110],"five-fold":[112],"axis":[113],"wild-type":[116],"capsid,":[118,171],"which":[119,144,151],"can":[120],"be":[121],"disrupted":[122],"an":[124,174],"located":[126],"pore.":[129],"Second,":[130],"channel":[132],"enables":[133],"protons":[134],"permeate":[136],"through":[139,150],"unidirectional":[141],"Grotthuss-like":[142],"mechanism,":[143],"is":[145],"most":[147],"likely":[148],"process":[149],"senses":[154],"pH.":[155],"Finally,":[156],"assuming":[157],"leak":[161],"promotes":[162],"charge":[164],"imbalance":[165],"interior":[168],"model":[173],"internal":[175],"pressure":[176],"forces":[178],"shell":[179],"cracking":[180],"using":[181,212],"coarse-grained":[182],"simulations.":[183],"Although":[184],"qualitatively,":[185],"last":[187],"step":[188],"could":[189,221],"represent":[190],"mechanism":[192],"opening":[195],"allows":[197],"RNA":[198],"All":[200],"our":[202],"are":[204],"agreement":[206],"with":[207],"current":[208],"experimental":[209],"data":[210],"obtained":[211],"TrV":[213],"describe":[215],"cascade":[217],"events":[219],"explain":[222],"destabilization":[224],"disassembly":[226],"similar":[228]},"counts_by_year":[{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":1}],"updated_date":"2026-05-06T08:25:59.206177","created_date":"2025-10-10T00:00:00"}