{"id":"https://openalex.org/W2616621860","doi":"https://doi.org/10.1371/journal.pcbi.1005539","title":"SteadyCom: Predicting microbial abundances while ensuring community stability","display_name":"SteadyCom: Predicting microbial abundances while ensuring community stability","publication_year":2017,"publication_date":"2017-05-15","ids":{"openalex":"https://openalex.org/W2616621860","doi":"https://doi.org/10.1371/journal.pcbi.1005539","mag":"2616621860","pmid":"https://pubmed.ncbi.nlm.nih.gov/28505184"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pcbi.1005539","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1005539","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1005539&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1005539&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5001997933","display_name":"Siu Hung Joshua Chan","orcid":"https://orcid.org/0000-0002-7707-656X"},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Siu Hung Joshua Chan","raw_affiliation_strings":["Department of Chemical Engineering, The Pennsylvania State University, University Park, Pennsylvania, United States of America"],"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering, The Pennsylvania State University, University Park, Pennsylvania, United States of America","institution_ids":["https://openalex.org/I130769515"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022228924","display_name":"Margaret Simons","orcid":"https://orcid.org/0000-0002-3010-229X"},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Margaret N. Simons","raw_affiliation_strings":["Department of Chemical Engineering, The Pennsylvania State University, University Park, Pennsylvania, United States of America"],"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering, The Pennsylvania State University, University Park, Pennsylvania, United States of America","institution_ids":["https://openalex.org/I130769515"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5083581014","display_name":"Costas D. Maranas","orcid":"https://orcid.org/0000-0002-1508-1398"},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Costas D. Maranas","raw_affiliation_strings":["Department of Chemical Engineering, The Pennsylvania State University, University Park, Pennsylvania, United States of America"],"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering, The Pennsylvania State University, University Park, Pennsylvania, United States of America","institution_ids":["https://openalex.org/I130769515"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5001997933","https://openalex.org/A5022228924","https://openalex.org/A5083581014"],"corresponding_institution_ids":["https://openalex.org/I130769515"],"apc_list":{"value":2655,"currency":"USD","value_usd":2655},"apc_paid":{"value":2655,"currency":"USD","value_usd":2655},"fwci":8.5344,"has_fulltext":true,"cited_by_count":242,"citation_normalized_percentile":{"value":0.98410567,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":97,"max":100},"biblio":{"volume":"13","issue":"5","first_page":"e1005539","last_page":"e1005539"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.9991999864578247,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9789999723434448,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/firmicutes","display_name":"Firmicutes","score":0.8077036738395691},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.6465585231781006},{"id":"https://openalex.org/keywords/bacteroidetes","display_name":"Bacteroidetes","score":0.6122797727584839},{"id":"https://openalex.org/keywords/proteobacteria","display_name":"Proteobacteria","score":0.5948790311813354},{"id":"https://openalex.org/keywords/microbial-population-biology","display_name":"Microbial population biology","score":0.5727517008781433},{"id":"https://openalex.org/keywords/abundance","display_name":"Abundance (ecology)","score":0.49331822991371155},{"id":"https://openalex.org/keywords/ecology","display_name":"Ecology","score":0.4636116921901703},{"id":"https://openalex.org/keywords/actinobacteria","display_name":"Actinobacteria","score":0.46111300587654114},{"id":"https://openalex.org/keywords/systems-biology","display_name":"Systems biology","score":0.4591834247112274},{"id":"https://openalex.org/keywords/organism","display_name":"Organism","score":0.4241294264793396},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.3980453610420227},{"id":"https://openalex.org/keywords/biochemical-engineering","display_name":"Biochemical engineering","score":0.38666439056396484},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.29159197211265564},{"id":"https://openalex.org/keywords/bacteria","display_name":"Bacteria","score":0.11788451671600342}],"concepts":[{"id":"https://openalex.org/C2777695942","wikidata":"https://www.wikidata.org/wiki/Q149075","display_name":"Firmicutes","level":4,"score":0.8077036738395691},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6465585231781006},{"id":"https://openalex.org/C2777385719","wikidata":"https://www.wikidata.org/wiki/Q1061265","display_name":"Bacteroidetes","level":4,"score":0.6122797727584839},{"id":"https://openalex.org/C2779676784","wikidata":"https://www.wikidata.org/wiki/Q130999","display_name":"Proteobacteria","level":4,"score":0.5948790311813354},{"id":"https://openalex.org/C81407943","wikidata":"https://www.wikidata.org/wiki/Q17149178","display_name":"Microbial population biology","level":3,"score":0.5727517008781433},{"id":"https://openalex.org/C77077793","wikidata":"https://www.wikidata.org/wiki/Q336019","display_name":"Abundance (ecology)","level":2,"score":0.49331822991371155},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.4636116921901703},{"id":"https://openalex.org/C2778169975","wikidata":"https://www.wikidata.org/wiki/Q130914","display_name":"Actinobacteria","level":4,"score":0.46111300587654114},{"id":"https://openalex.org/C152662350","wikidata":"https://www.wikidata.org/wiki/Q815297","display_name":"Systems biology","level":2,"score":0.4591834247112274},{"id":"https://openalex.org/C137858568","wikidata":"https://www.wikidata.org/wiki/Q7239","display_name":"Organism","level":2,"score":0.4241294264793396},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3980453610420227},{"id":"https://openalex.org/C183696295","wikidata":"https://www.wikidata.org/wiki/Q2487696","display_name":"Biochemical engineering","level":1,"score":0.38666439056396484},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.29159197211265564},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.11788451671600342},{"id":"https://openalex.org/C42062724","wikidata":"https://www.wikidata.org/wiki/Q1209205","display_name":"16S ribosomal RNA","level":3,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053858","descriptor_name":"Metabolic Networks and Pathways","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D053858","descriptor_name":"Metabolic Networks and Pathways","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D053858","descriptor_name":"Metabolic Networks and Pathways","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D059013","descriptor_name":"Microbial Consortia","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D059013","descriptor_name":"Microbial Consortia","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D059013","descriptor_name":"Microbial Consortia","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D064688","descriptor_name":"Metabolic Flux Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D064688","descriptor_name":"Metabolic Flux Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D064688","descriptor_name":"Metabolic Flux Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":9,"locations":[{"id":"doi:10.1371/journal.pcbi.1005539","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1005539","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1005539&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},{"id":"pmid:28505184","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28505184","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS computational biology","raw_type":null},{"id":"pmh:oai:doaj.org/article:2a68edd0e3d640de91b6038d21c37d46","is_oa":true,"landing_page_url":"https://doaj.org/article/2a68edd0e3d640de91b6038d21c37d46","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Computational Biology, Vol 13, Iss 5, p e1005539 (2017)","raw_type":"article"},{"id":"pmh:oai:europepmc.org:4311825","is_oa":true,"landing_page_url":"http://europepmc.org/articles/PMC5448816","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:figshare.com:article/5006267","is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/SteadyCom_Predicting_microbial_abundances_while_ensuring_community_stability/5006267","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"},{"id":"pmh:oai:osti.gov:1356874","is_oa":true,"landing_page_url":"https://www.osti.gov/biblio/1356874","pdf_url":null,"source":{"id":"https://openalex.org/S4306402487","display_name":"OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I139351228","host_organization_name":"Office of Scientific and Technical Information","host_organization_lineage":["https://openalex.org/I139351228"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},{"id":"pmh:oai:osti.gov:1360660","is_oa":true,"landing_page_url":"https://www.osti.gov/biblio/1360660","pdf_url":null,"source":{"id":"https://openalex.org/S4306402487","display_name":"OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I139351228","host_organization_name":"Office of Scientific and Technical Information","host_organization_lineage":["https://openalex.org/I139351228"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},{"id":"pmh:oai:osti.gov:1393505","is_oa":true,"landing_page_url":"https://www.osti.gov/biblio/1393505","pdf_url":null,"source":{"id":"https://openalex.org/S4306402487","display_name":"OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I139351228","host_organization_name":"Office of Scientific and Technical Information","host_organization_lineage":["https://openalex.org/I139351228"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:5448816","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5448816","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Comput Biol","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1371/journal.pcbi.1005539","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1005539","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1005539&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/15","score":0.6700000166893005,"display_name":"Life in Land"}],"awards":[{"id":"https://openalex.org/G5771032755","display_name":null,"funder_award_id":"DE-SC0008091","funder_id":"https://openalex.org/F4320306084","funder_display_name":"U.S. Department of Energy"},{"id":"https://openalex.org/G851480045","display_name":null,"funder_award_id":"#DE-SC0008091","funder_id":"https://openalex.org/F4320306084","funder_display_name":"U.S. Department of Energy"}],"funders":[{"id":"https://openalex.org/F4320306084","display_name":"U.S. Department of Energy","ror":"https://ror.org/01bj3aw27"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2616621860.pdf","grobid_xml":"https://content.openalex.org/works/W2616621860.grobid-xml"},"referenced_works_count":80,"referenced_works":["https://openalex.org/W1498456815","https://openalex.org/W1754578874","https://openalex.org/W1793035576","https://openalex.org/W1832079889","https://openalex.org/W1966497610","https://openalex.org/W1970559599","https://openalex.org/W1974662378","https://openalex.org/W1976253726","https://openalex.org/W1978408474","https://openalex.org/W1981535807","https://openalex.org/W1982013068","https://openalex.org/W1984445372","https://openalex.org/W1992198528","https://openalex.org/W1998783353","https://openalex.org/W2011514820","https://openalex.org/W2012994611","https://openalex.org/W2015519162","https://openalex.org/W2019516978","https://openalex.org/W2022012525","https://openalex.org/W2025276733","https://openalex.org/W2027763661","https://openalex.org/W2029403511","https://openalex.org/W2032230795","https://openalex.org/W2032336323","https://openalex.org/W2033829415","https://openalex.org/W2045328524","https://openalex.org/W2054016222","https://openalex.org/W2054087105","https://openalex.org/W2061853512","https://openalex.org/W2067480709","https://openalex.org/W2076262841","https://openalex.org/W2076393137","https://openalex.org/W2077149408","https://openalex.org/W2077980171","https://openalex.org/W2079811188","https://openalex.org/W2086196945","https://openalex.org/W2087292184","https://openalex.org/W2088170171","https://openalex.org/W2088209062","https://openalex.org/W2097124003","https://openalex.org/W2099536218","https://openalex.org/W2103088074","https://openalex.org/W2111381495","https://openalex.org/W2113882071","https://openalex.org/W2116846792","https://openalex.org/W2117509624","https://openalex.org/W2117595393","https://openalex.org/W2120469353","https://openalex.org/W2121488951","https://openalex.org/W2122093325","https://openalex.org/W2124737787","https://openalex.org/W2126218947","https://openalex.org/W2126452774","https://openalex.org/W2128769815","https://openalex.org/W2128970129","https://openalex.org/W2129239774","https://openalex.org/W2136552678","https://openalex.org/W2136939284","https://openalex.org/W2137195441","https://openalex.org/W2140937954","https://openalex.org/W2142500268","https://openalex.org/W2144568881","https://openalex.org/W2149573313","https://openalex.org/W2151643303","https://openalex.org/W2152289100","https://openalex.org/W2152538010","https://openalex.org/W2152670890","https://openalex.org/W2162314899","https://openalex.org/W2164549452","https://openalex.org/W2169330513","https://openalex.org/W2169527381","https://openalex.org/W2170427655","https://openalex.org/W2177687538","https://openalex.org/W2409622550","https://openalex.org/W2465128457","https://openalex.org/W2510201597","https://openalex.org/W2510643880","https://openalex.org/W2734603555","https://openalex.org/W2952564192","https://openalex.org/W3104005457"],"related_works":["https://openalex.org/W4378449334","https://openalex.org/W2326469777","https://openalex.org/W2201410296","https://openalex.org/W1988111326","https://openalex.org/W2399012903","https://openalex.org/W2369806802","https://openalex.org/W1976709164","https://openalex.org/W2357176030","https://openalex.org/W3014274500","https://openalex.org/W3182034478"],"abstract_inverted_index":{"Genome-scale":[0],"metabolic":[1,124],"modeling":[2,38],"has":[3,48],"become":[4],"widespread":[5],"for":[6,43,64,95,122,171],"analyzing":[7],"microbial":[8,17,44,271],"metabolism.":[9],"Extending":[10],"this":[11,76,114],"established":[12],"paradigm":[13],"to":[14,25,54,67,185,206,215,224,250],"more":[15],"complex":[16],"communities":[18],"is":[19,92,149,161,168,182,213,254],"emerging":[20],"as":[21,100],"a":[22,56,65,172,186,247,270,274],"promising":[23],"way":[24],"unravel":[26],"the":[27,52,73,78,89,106,118,129,145,152,197,207,217,234,238,262,267],"interactions":[28],"and":[29,70,111,144,181,202],"biochemical":[30],"repertoire":[31],"of":[32,75,147,151,154,159,174,191,210,241,265,269],"these":[33],"omnipresent":[34],"systems.":[35],"While":[36],"several":[37],"techniques":[39],"have":[40],"been":[41,49],"developed":[42],"communities,":[45],"little":[46],"emphasis":[47],"placed":[50],"on":[51,105,233],"need":[53],"impose":[55],"time-averaged":[57],"constant":[58],"growth":[59],"rate":[60],"across":[61],"all":[62,85],"members":[63],"community":[66,108,173,272],"ensure":[68],"co-existence":[69],"stability.":[71],"In":[72,113,204],"absence":[74],"constraint,":[77],"faster":[79],"growing":[80],"organism":[81],"will":[82],"ultimately":[83],"displace":[84],"other":[86],"microbes":[87],"in":[88,219,222,226,273],"community.":[90],"This":[91],"particularly":[93],"important":[94,259],"predicting":[96,123,266],"steady-state":[97,130],"microbiota":[98,188,253],"composition":[99,110,268],"it":[101],"imposes":[102],"significant":[103,157],"restrictions":[104],"allowable":[107],"membership,":[109],"phenotypes.":[112],"study,":[115],"we":[116],"introduce":[117],"SteadyCom":[119,132,160,167,212,256],"optimization":[120],"framework":[121],"flux":[125,164],"distributions":[126],"consistent":[127],"with":[128,163,194,228,246],"requirement.":[131],"can":[133],"be":[134],"rapidly":[135],"converged":[136],"by":[137],"iteratively":[138],"solving":[139],"linear":[140],"programming":[141],"(LP)":[142],"problem":[143],"number":[146,153],"iterations":[148],"independent":[150],"organisms.":[155],"A":[156],"advantage":[158],"compatibility":[162],"variability":[165],"analysis.":[166],"first":[169],"demonstrated":[170],"four":[175],"E.":[176],"coli":[177],"double":[178],"auxotrophic":[179],"mutants":[180],"then":[183],"applied":[184],"gut":[187,252],"model":[189],"consisting":[190],"nine":[192],"species,":[193],"representatives":[195],"from":[196],"phyla":[198],"Bacteroidetes,":[199],"Firmicutes,":[200],"Actinobacteria":[201],"Proteobacteria.":[203],"contrast":[205],"direct":[208],"use":[209],"FBA,":[211],"able":[214],"predict":[216],"change":[218],"species":[220],"abundance":[221,244],"response":[223],"changes":[225],"diets":[227],"minimal":[229],"additional":[230],"imposed":[231],"constraints":[232],"model.":[235],"By":[236],"randomizing":[237],"uptake":[239],"rates":[240],"microbes,":[242],"an":[243,258],"profile":[245],"good":[248],"agreement":[249],"experimental":[251],"inferred.":[255],"provides":[257],"step":[260],"towards":[261],"cross-cutting":[263],"task":[264],"given":[275],"environment.":[276]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":26},{"year":2024,"cited_by_count":49},{"year":2023,"cited_by_count":26},{"year":2022,"cited_by_count":30},{"year":2021,"cited_by_count":31},{"year":2020,"cited_by_count":29},{"year":2019,"cited_by_count":29},{"year":2018,"cited_by_count":14},{"year":2017,"cited_by_count":4}],"updated_date":"2026-04-03T22:45:19.894376","created_date":"2025-10-10T00:00:00"}