{"id":"https://openalex.org/W2519110907","doi":"https://doi.org/10.1371/journal.pcbi.1005052","title":"A Model of the Spatio-temporal Dynamics of Drosophila Eye Disc Development","display_name":"A Model of the Spatio-temporal Dynamics of Drosophila Eye Disc Development","publication_year":2016,"publication_date":"2016-09-14","ids":{"openalex":"https://openalex.org/W2519110907","doi":"https://doi.org/10.1371/journal.pcbi.1005052","mag":"2519110907","pmid":"https://pubmed.ncbi.nlm.nih.gov/27626238"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pcbi.1005052","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1005052","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1005052&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","datacite","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1005052&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5016516562","display_name":"Patrick Fried","orcid":null},"institutions":[{"id":"https://openalex.org/I12708293","display_name":"SIB Swiss Institute of Bioinformatics","ror":"https://ror.org/002n09z45","country_code":"CH","type":"nonprofit","lineage":["https://openalex.org/I12708293"]},{"id":"https://openalex.org/I35440088","display_name":"ETH Zurich","ror":"https://ror.org/05a28rw58","country_code":"CH","type":"education","lineage":["https://openalex.org/I2799323385","https://openalex.org/I35440088"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Patrick Fried","raw_affiliation_strings":["Department of Biosystems, Science and Engineering (D-BSSE), ETH Zurich, Basel, Switzerland","Swiss Institute of Bioinformatics (SIB), Basel, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biosystems, Science and Engineering (D-BSSE), ETH Zurich, Basel, Switzerland","institution_ids":["https://openalex.org/I35440088"]},{"raw_affiliation_string":"Swiss Institute of Bioinformatics (SIB), Basel, Switzerland","institution_ids":["https://openalex.org/I12708293"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085875595","display_name":"M\u00e1ximo S\u00e1nchez-Arag\u00f3n","orcid":"https://orcid.org/0000-0002-8221-7718"},"institutions":[{"id":"https://openalex.org/I95013407","display_name":"Universidad Pablo de Olavide","ror":"https://ror.org/02z749649","country_code":"ES","type":"education","lineage":["https://openalex.org/I95013407"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"M\u00e1ximo S\u00e1nchez-Arag\u00f3n","raw_affiliation_strings":["CABD, CSIC and Universidad Pablo de Olavide, Campus UPO, Seville, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CABD, CSIC and Universidad Pablo de Olavide, Campus UPO, Seville, Spain","institution_ids":["https://openalex.org/I95013407"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068186030","display_name":"Daniel Aguilar\u2010Hidalgo","orcid":"https://orcid.org/0000-0003-1366-9574"},"institutions":[{"id":"https://openalex.org/I95013407","display_name":"Universidad Pablo de Olavide","ror":"https://ror.org/02z749649","country_code":"ES","type":"education","lineage":["https://openalex.org/I95013407"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Daniel Aguilar-Hidalgo","raw_affiliation_strings":["CABD, CSIC and Universidad Pablo de Olavide, Campus UPO, Seville, Spain"],"raw_orcid":"https://orcid.org/0000-0003-1366-9574","affiliations":[{"raw_affiliation_string":"CABD, CSIC and Universidad Pablo de Olavide, Campus UPO, Seville, Spain","institution_ids":["https://openalex.org/I95013407"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113842016","display_name":"Birgitta Lehtinen","orcid":null},"institutions":[{"id":"https://openalex.org/I35440088","display_name":"ETH Zurich","ror":"https://ror.org/05a28rw58","country_code":"CH","type":"education","lineage":["https://openalex.org/I2799323385","https://openalex.org/I35440088"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Birgitta Lehtinen","raw_affiliation_strings":["Department of Biosystems, Science and Engineering (D-BSSE), ETH Zurich, Basel, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biosystems, Science and Engineering (D-BSSE), ETH Zurich, Basel, Switzerland","institution_ids":["https://openalex.org/I35440088"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023570604","display_name":"Fernando Casares","orcid":"https://orcid.org/0000-0002-2181-3858"},"institutions":[{"id":"https://openalex.org/I95013407","display_name":"Universidad Pablo de Olavide","ror":"https://ror.org/02z749649","country_code":"ES","type":"education","lineage":["https://openalex.org/I95013407"]}],"countries":["ES"],"is_corresponding":true,"raw_author_name":"Fernando Casares","raw_affiliation_strings":["CABD, CSIC and Universidad Pablo de Olavide, Campus UPO, Seville, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CABD, CSIC and Universidad Pablo de Olavide, Campus UPO, Seville, Spain","institution_ids":["https://openalex.org/I95013407"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5000913635","display_name":"Dagmar Iber","orcid":"https://orcid.org/0000-0001-8051-1035"},"institutions":[{"id":"https://openalex.org/I12708293","display_name":"SIB Swiss Institute of Bioinformatics","ror":"https://ror.org/002n09z45","country_code":"CH","type":"nonprofit","lineage":["https://openalex.org/I12708293"]},{"id":"https://openalex.org/I35440088","display_name":"ETH Zurich","ror":"https://ror.org/05a28rw58","country_code":"CH","type":"education","lineage":["https://openalex.org/I2799323385","https://openalex.org/I35440088"]}],"countries":["CH"],"is_corresponding":true,"raw_author_name":"Dagmar Iber","raw_affiliation_strings":["Department of Biosystems, Science and Engineering (D-BSSE), ETH Zurich, Basel, Switzerland","Swiss Institute of Bioinformatics (SIB), Basel, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biosystems, Science and Engineering (D-BSSE), ETH Zurich, Basel, Switzerland","institution_ids":["https://openalex.org/I35440088"]},{"raw_affiliation_string":"Swiss Institute of Bioinformatics (SIB), Basel, Switzerland","institution_ids":["https://openalex.org/I12708293"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5000913635","https://openalex.org/A5023570604"],"corresponding_institution_ids":["https://openalex.org/I12708293","https://openalex.org/I35440088","https://openalex.org/I95013407"],"apc_list":{"value":2655,"currency":"USD","value_usd":2655},"apc_paid":{"value":2184,"currency":"EUR","value_usd":2355},"fwci":1.9148,"has_fulltext":true,"cited_by_count":36,"citation_normalized_percentile":{"value":0.86280571,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"12","issue":"9","first_page":"e1005052","last_page":"e1005052"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.9991000294685364,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.9991000294685364,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12065","display_name":"Hippo pathway signaling and YAP/TAZ","score":0.9897000193595886,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10929","display_name":"Wnt/\u03b2-catenin signaling in development and cancer","score":0.9789000153541565,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/decapentaplegic","display_name":"Decapentaplegic","score":0.8895146250724792},{"id":"https://openalex.org/keywords/primordium","display_name":"Primordium","score":0.712171196937561},{"id":"https://openalex.org/keywords/hedgehog","display_name":"Hedgehog","score":0.7053884267807007},{"id":"https://openalex.org/keywords/imaginal-disc","display_name":"Imaginal disc","score":0.6591928601264954},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.6120666861534119},{"id":"https://openalex.org/keywords/eye-development","display_name":"Eye development","score":0.5550275444984436},{"id":"https://openalex.org/keywords/compartment","display_name":"Compartment (ship)","score":0.5107748508453369},{"id":"https://openalex.org/keywords/cell-biology","display_name":"Cell biology","score":0.5083431601524353},{"id":"https://openalex.org/keywords/dynamics","display_name":"Dynamics (music)","score":0.4195474088191986},{"id":"https://openalex.org/keywords/anatomy","display_name":"Anatomy","score":0.41759639978408813},{"id":"https://openalex.org/keywords/phenotype","display_name":"Phenotype","score":0.40936213731765747},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.3394954204559326},{"id":"https://openalex.org/keywords/signal-transduction","display_name":"Signal transduction","score":0.25711148977279663},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.19183534383773804},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.1277589201927185},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.08648395538330078}],"concepts":[{"id":"https://openalex.org/C2776735322","wikidata":"https://www.wikidata.org/wiki/Q976767","display_name":"Decapentaplegic","level":5,"score":0.8895146250724792},{"id":"https://openalex.org/C184750944","wikidata":"https://www.wikidata.org/wiki/Q557677","display_name":"Primordium","level":3,"score":0.712171196937561},{"id":"https://openalex.org/C2778539099","wikidata":"https://www.wikidata.org/wiki/Q6120","display_name":"Hedgehog","level":3,"score":0.7053884267807007},{"id":"https://openalex.org/C91986751","wikidata":"https://www.wikidata.org/wiki/Q996011","display_name":"Imaginal disc","level":4,"score":0.6591928601264954},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6120666861534119},{"id":"https://openalex.org/C114696181","wikidata":"https://www.wikidata.org/wiki/Q5422650","display_name":"Eye development","level":4,"score":0.5550275444984436},{"id":"https://openalex.org/C203635412","wikidata":"https://www.wikidata.org/wiki/Q17007432","display_name":"Compartment (ship)","level":2,"score":0.5107748508453369},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5083431601524353},{"id":"https://openalex.org/C145912823","wikidata":"https://www.wikidata.org/wiki/Q113558","display_name":"Dynamics (music)","level":2,"score":0.4195474088191986},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.41759639978408813},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.40936213731765747},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.3394954204559326},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.25711148977279663},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.19183534383773804},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.1277589201927185},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.08648395538330078},{"id":"https://openalex.org/C127313418","wikidata":"https://www.wikidata.org/wiki/Q1069","display_name":"Geology","level":0,"score":0.0},{"id":"https://openalex.org/C24890656","wikidata":"https://www.wikidata.org/wiki/Q82811","display_name":"Acoustics","level":1,"score":0.0},{"id":"https://openalex.org/C111368507","wikidata":"https://www.wikidata.org/wiki/Q43518","display_name":"Oceanography","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004330","descriptor_name":"Drosophila","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D004330","descriptor_name":"Drosophila","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D004330","descriptor_name":"Drosophila","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D004330","descriptor_name":"Drosophila","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D005123","descriptor_name":"Eye","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D005123","descriptor_name":"Eye","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D005123","descriptor_name":"Eye","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D005123","descriptor_name":"Eye","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D009024","descriptor_name":"Morphogenesis","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009024","descriptor_name":"Morphogenesis","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009024","descriptor_name":"Morphogenesis","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009024","descriptor_name":"Morphogenesis","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D029721","descriptor_name":"Drosophila Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D029721","descriptor_name":"Drosophila Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D029721","descriptor_name":"Drosophila Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D029721","descriptor_name":"Drosophila Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D062211","descriptor_name":"Spatio-Temporal Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D062211","descriptor_name":"Spatio-Temporal Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D062211","descriptor_name":"Spatio-Temporal Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D062211","descriptor_name":"Spatio-Temporal Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":10,"locations":[{"id":"doi:10.1371/journal.pcbi.1005052","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1005052","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1005052&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},{"id":"pmid:27626238","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/27626238","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS computational biology","raw_type":null},{"id":"pmh:oai:eprints.gla.ac.uk:306600","is_oa":false,"landing_page_url":null,"pdf_url":null,"source":{"id":"https://openalex.org/S4210235606","display_name":"ENLIGHTEN (Jurnal Bimbingan dan Konseling Islam)","issn_l":"2622-8912","issn":["2622-8912","2622-8920"],"is_oa":false,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Articles"},{"id":"pmh:oai:digital.csic.es:10261/163153","is_oa":true,"landing_page_url":"http://hdl.handle.net/10261/163153","pdf_url":null,"source":{"id":"https://openalex.org/S4306400616","display_name":"DIGITAL.CSIC (Spanish National Research Council (CSIC))","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I134820265","host_organization_name":"Consejo Superior de Investigaciones Cient\u00edficas","host_organization_lineage":["https://openalex.org/I134820265"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"art\u00edculo"},{"id":"pmh:oai:doaj.org/article:31d3a690bb1848f9ac4cf46d94a04234","is_oa":true,"landing_page_url":"https://doaj.org/article/31d3a690bb1848f9ac4cf46d94a04234","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Computational Biology, Vol 12, Iss 9, p e1005052 (2016)","raw_type":"article"},{"id":"pmh:oai:figshare.com:article/3832821","is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/A_Model_of_the_Spatio-temporal_Dynamics_of_i_Drosophila_i_Eye_Disc_Development/3832821","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"},{"id":"pmh:oai:pubmedcentral.nih.gov:5023109","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5023109","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Comput Biol","raw_type":"Text"},{"id":"pmh:oai:pure.mpg.de:item_2378580","is_oa":false,"landing_page_url":"http://hdl.handle.net/11858/00-001M-0000-002C-32DC-7","pdf_url":null,"source":{"id":"https://openalex.org/S4306400654","display_name":"MPG.PuRe (Max Planck Society)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I149899117","host_organization_name":"Max Planck Society","host_organization_lineage":["https://openalex.org/I149899117"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Computational Biology","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:www.research-collection.ethz.ch:20.500.11850/120241","is_oa":true,"landing_page_url":"http://hdl.handle.net/20.500.11850/120241","pdf_url":null,"source":{"id":"https://openalex.org/S4306402302","display_name":"Repository for Publications and Research Data (ETH Zurich)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I35440088","host_organization_name":"ETH Zurich","host_organization_lineage":["https://openalex.org/I35440088"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Computational Biology, 12 (9)","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"doi:10.3929/ethz-b-000120241","is_oa":true,"landing_page_url":"https://doi.org/10.3929/ethz-b-000120241","pdf_url":null,"source":{"id":"https://openalex.org/S7407051236","display_name":"ETH Z\u00fcrich Research Collection","issn_l":null,"issn":[],"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":null,"raw_source_name":null,"raw_type":"article-journal"}],"best_oa_location":{"id":"doi:10.1371/journal.pcbi.1005052","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1005052","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1005052&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G3180073641","display_name":null,"funder_award_id":"BFU2015-66040","funder_id":"https://openalex.org/F4320321837","funder_display_name":"Ministerio de Econom\u00eda y Competitividad"},{"id":"https://openalex.org/G4192033369","display_name":null,"funder_award_id":"BFU2012-34324","funder_id":"https://openalex.org/F4320321837","funder_display_name":"Ministerio de Econom\u00eda y Competitividad"}],"funders":[{"id":"https://openalex.org/F4320321837","display_name":"Ministerio de Econom\u00eda y Competitividad","ror":"https://ror.org/034900433"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2519110907.pdf","grobid_xml":"https://content.openalex.org/works/W2519110907.grobid-xml"},"referenced_works_count":60,"referenced_works":["https://openalex.org/W1534968983","https://openalex.org/W1664008877","https://openalex.org/W1965558704","https://openalex.org/W1976925230","https://openalex.org/W1977027703","https://openalex.org/W1977504844","https://openalex.org/W1978772056","https://openalex.org/W1986080505","https://openalex.org/W1994844861","https://openalex.org/W1998020029","https://openalex.org/W2000092886","https://openalex.org/W2001752489","https://openalex.org/W2002206208","https://openalex.org/W2006033261","https://openalex.org/W2007452808","https://openalex.org/W2010287515","https://openalex.org/W2023229923","https://openalex.org/W2028618047","https://openalex.org/W2029042594","https://openalex.org/W2036769854","https://openalex.org/W2038743187","https://openalex.org/W2047531379","https://openalex.org/W2049274348","https://openalex.org/W2049435858","https://openalex.org/W2053945557","https://openalex.org/W2054464790","https://openalex.org/W2064121506","https://openalex.org/W2065294112","https://openalex.org/W2065418058","https://openalex.org/W2068068030","https://openalex.org/W2068909410","https://openalex.org/W2069528220","https://openalex.org/W2071199204","https://openalex.org/W2074099368","https://openalex.org/W2076840943","https://openalex.org/W2079320801","https://openalex.org/W2090661447","https://openalex.org/W2092252450","https://openalex.org/W2097131990","https://openalex.org/W2102230555","https://openalex.org/W2103872813","https://openalex.org/W2105584204","https://openalex.org/W2119594523","https://openalex.org/W2120995883","https://openalex.org/W2121403037","https://openalex.org/W2122289311","https://openalex.org/W2124148849","https://openalex.org/W2125392305","https://openalex.org/W2128908241","https://openalex.org/W2133951989","https://openalex.org/W2137202581","https://openalex.org/W2138222765","https://openalex.org/W2152900108","https://openalex.org/W2153640859","https://openalex.org/W2157355630","https://openalex.org/W2166163519","https://openalex.org/W2177485263","https://openalex.org/W2193977748","https://openalex.org/W2294769819","https://openalex.org/W2414216809"],"related_works":["https://openalex.org/W1964390223","https://openalex.org/W2041970325","https://openalex.org/W2099249412","https://openalex.org/W2091832169","https://openalex.org/W1871724379","https://openalex.org/W2002206208","https://openalex.org/W2183779822","https://openalex.org/W1939431494","https://openalex.org/W2131906224","https://openalex.org/W4313317467"],"abstract_inverted_index":{"Patterning":[0],"and":[1,8,76,97,133,139,151,160,179,199],"growth":[2,35,203],"are":[3],"linked":[4],"during":[5],"early":[6],"development":[7,24],"have":[9],"to":[10,14,63,72,74,164,191,220],"be":[11],"tightly":[12],"controlled":[13,125],"result":[15],"in":[16,81,230],"a":[17,51,112],"functional":[18],"tissue":[19,59],"or":[20],"organ.":[21],"During":[22],"the":[23,26,34,37,47,58,61,64,91,99,103,107,116,122,127,134,142,146,149,166,174,180,193,197,200,205,211,222,227,231],"of":[25,36,46,94,115,148,177,183,196,202,204,226],"Drosophila":[27],"eye,":[28],"this":[29],"linkage":[30],"is":[31,189],"particularly":[32],"clear:":[33],"eye":[38,86,108,118,154],"primordium":[39],"mainly":[40],"results":[41],"from":[42,60],"proliferating":[43,69],"cells":[44,70,96],"ahead":[45],"morphogenetic":[48],"furrow":[49],"(MF),":[50],"moving":[52],"signaling":[53,143],"wave":[54],"that":[55,67,210],"sweeps":[56,105],"across":[57,106],"posterior":[62],"anterior":[65,71,232],"side,":[66],"induces":[68],"it":[73],"differentiate":[75],"become":[77],"cell":[78],"cycle":[79],"quiescent":[80],"its":[82],"wake.":[83],"Therefore,":[84],"final":[85],"disc":[87,119,155],"size":[88],"depends":[89],"on":[90,98,121,153],"proliferation":[92],"rate":[93,176],"undifferentiated":[95],"speed":[100],"with":[101],"which":[102],"MF":[104,150,198],"disc.":[109],"We":[110,157,207],"developed":[111],"spatio-temporal":[113],"model":[114,188,212],"growing":[117],"based":[120],"regulatory":[123],"interactions":[124],"by":[126],"signals":[128],"Decapentaplegic":[129],"(Dpp),":[130],"Hedgehog":[131],"(Hh)":[132],"transcription":[135],"factor":[136],"Homothorax":[137],"(Hth)":[138],"explored":[140],"how":[141],"patterns":[144],"affect":[145],"movement":[147,195],"impact":[152],"growth.":[156],"used":[158],"published":[159],"new":[161],"quantitative":[162],"data":[163],"parameterize":[165],"model.":[167],"In":[168],"particular,":[169],"two":[170],"crucial":[171],"parameter":[172],"values,":[173],"degradation":[175],"Hth":[178],"diffusion":[181],"coefficient":[182],"Hh,":[184],"were":[185],"measured.":[186],"The":[187],"able":[190],"reproduce":[192,221],"linear":[194],"termination":[201],"primordium.":[206],"further":[208],"show":[209],"can":[213],"explain":[214],"several":[215],"mutant":[216],"phenotypes,":[217],"but":[218],"fails":[219],"previously":[223],"observed":[224],"scaling":[225],"Dpp":[228],"gradient":[229],"compartment.":[233]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":11},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":4}],"updated_date":"2026-05-06T08:25:59.206177","created_date":"2025-10-10T00:00:00"}