{"id":"https://openalex.org/W2394883599","doi":"https://doi.org/10.1371/journal.pcbi.1004929","title":"Biophysical Network Modelling of the dLGN Circuit: Different Effects of Triadic and Axonal Inhibition on Visual Responses of Relay Cells","display_name":"Biophysical Network Modelling of the dLGN Circuit: Different Effects of Triadic and Axonal Inhibition on Visual Responses of Relay Cells","publication_year":2016,"publication_date":"2016-05-20","ids":{"openalex":"https://openalex.org/W2394883599","doi":"https://doi.org/10.1371/journal.pcbi.1004929","mag":"2394883599","pmid":"https://pubmed.ncbi.nlm.nih.gov/27203421"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pcbi.1004929","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1004929","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1004929&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1004929&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5007863460","display_name":"Thomas Heiberg","orcid":null},"institutions":[{"id":"https://openalex.org/I54108979","display_name":"Norwegian University of Life Sciences","ror":"https://ror.org/04a1mvv97","country_code":"NO","type":"education","lineage":["https://openalex.org/I54108979"]}],"countries":["NO"],"is_corresponding":false,"raw_author_name":"Thomas Heiberg","raw_affiliation_strings":["Department of Mathematical Sciences and Technology, Norwegian University of Life Sciences, \u00c5s, Norway"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Mathematical Sciences and Technology, Norwegian University of Life Sciences, \u00c5s, Norway","institution_ids":["https://openalex.org/I54108979"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040379244","display_name":"Espen Hagen","orcid":"https://orcid.org/0000-0002-1321-5970"},"institutions":[{"id":"https://openalex.org/I171892758","display_name":"Forschungszentrum J\u00fclich","ror":"https://ror.org/02nv7yv05","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I171892758"]},{"id":"https://openalex.org/I4210133912","display_name":"J\u00fclich Aachen Research Alliance","ror":"https://ror.org/02r0e4r58","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I171892758","https://openalex.org/I4210133912"]},{"id":"https://openalex.org/I54108979","display_name":"Norwegian University of Life Sciences","ror":"https://ror.org/04a1mvv97","country_code":"NO","type":"education","lineage":["https://openalex.org/I54108979"]}],"countries":["DE","NO"],"is_corresponding":false,"raw_author_name":"Espen Hagen","raw_affiliation_strings":["Department of Mathematical Sciences and Technology, Norwegian University of Life Sciences, \u00c5s, Norway","Institute of Neuroscience and Medicine (INM-6) and Institute for Advanced Simulation (IAS-6) and JARA BRAIN Institute I, J\u00fclich Research Centre, J\u00fclich, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Mathematical Sciences and Technology, Norwegian University of Life Sciences, \u00c5s, Norway","institution_ids":["https://openalex.org/I54108979"]},{"raw_affiliation_string":"Institute of Neuroscience and Medicine (INM-6) and Institute for Advanced Simulation (IAS-6) and JARA BRAIN Institute I, J\u00fclich Research Centre, J\u00fclich, Germany","institution_ids":["https://openalex.org/I4210133912","https://openalex.org/I171892758"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083668294","display_name":"Geir Halnes","orcid":"https://orcid.org/0000-0002-4721-1599"},"institutions":[{"id":"https://openalex.org/I54108979","display_name":"Norwegian University of Life Sciences","ror":"https://ror.org/04a1mvv97","country_code":"NO","type":"education","lineage":["https://openalex.org/I54108979"]}],"countries":["NO"],"is_corresponding":false,"raw_author_name":"Geir Halnes","raw_affiliation_strings":["Department of Mathematical Sciences and Technology, Norwegian University of Life Sciences, \u00c5s, Norway"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Mathematical Sciences and Technology, Norwegian University of Life Sciences, \u00c5s, Norway","institution_ids":["https://openalex.org/I54108979"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5032715711","display_name":"Gaute T. Einevoll","orcid":"https://orcid.org/0000-0002-5425-5012"},"institutions":[{"id":"https://openalex.org/I184942183","display_name":"University of Oslo","ror":"https://ror.org/01xtthb56","country_code":"NO","type":"education","lineage":["https://openalex.org/I184942183"]},{"id":"https://openalex.org/I54108979","display_name":"Norwegian University of Life Sciences","ror":"https://ror.org/04a1mvv97","country_code":"NO","type":"education","lineage":["https://openalex.org/I54108979"]}],"countries":["NO"],"is_corresponding":true,"raw_author_name":"Gaute T. Einevoll","raw_affiliation_strings":["Department of Mathematical Sciences and Technology, Norwegian University of Life Sciences, \u00c5s, Norway","Department of Physics, University of Oslo, Oslo, Norway"],"raw_orcid":"https://orcid.org/0000-0002-5425-5012","affiliations":[{"raw_affiliation_string":"Department of Mathematical Sciences and Technology, Norwegian University of Life Sciences, \u00c5s, Norway","institution_ids":["https://openalex.org/I54108979"]},{"raw_affiliation_string":"Department of Physics, University of Oslo, Oslo, Norway","institution_ids":["https://openalex.org/I184942183"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5032715711"],"corresponding_institution_ids":["https://openalex.org/I184942183","https://openalex.org/I54108979"],"apc_list":{"value":2655,"currency":"USD","value_usd":2655},"apc_paid":{"value":2655,"currency":"USD","value_usd":2655},"fwci":1.0086,"has_fulltext":true,"cited_by_count":16,"citation_normalized_percentile":{"value":0.75433398,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":99},"biblio":{"volume":"12","issue":"5","first_page":"e1004929","last_page":"e1004929"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12236","display_name":"Photoreceptor and optogenetics research","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/receptive-field","display_name":"Receptive field","score":0.8546092510223389},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.7338383197784424},{"id":"https://openalex.org/keywords/visual-cortex","display_name":"Visual cortex","score":0.5712049007415771},{"id":"https://openalex.org/keywords/inhibitory-postsynaptic-potential","display_name":"Inhibitory postsynaptic potential","score":0.5532808899879456},{"id":"https://openalex.org/keywords/postsynaptic-potential","display_name":"Postsynaptic potential","score":0.5244269967079163},{"id":"https://openalex.org/keywords/lateral-geniculate-nucleus","display_name":"Lateral geniculate nucleus","score":0.5119150876998901},{"id":"https://openalex.org/keywords/retina","display_name":"Retina","score":0.4971654713153839},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.3645791709423065},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.3429808020591736},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.3382643461227417},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.3347480893135071}],"concepts":[{"id":"https://openalex.org/C19071747","wikidata":"https://www.wikidata.org/wiki/Q1755207","display_name":"Receptive field","level":2,"score":0.8546092510223389},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.7338383197784424},{"id":"https://openalex.org/C2779345533","wikidata":"https://www.wikidata.org/wiki/Q75785","display_name":"Visual cortex","level":2,"score":0.5712049007415771},{"id":"https://openalex.org/C17077164","wikidata":"https://www.wikidata.org/wiki/Q1185869","display_name":"Inhibitory postsynaptic potential","level":2,"score":0.5532808899879456},{"id":"https://openalex.org/C197341189","wikidata":"https://www.wikidata.org/wiki/Q863533","display_name":"Postsynaptic potential","level":3,"score":0.5244269967079163},{"id":"https://openalex.org/C2776362945","wikidata":"https://www.wikidata.org/wiki/Q719179","display_name":"Lateral geniculate nucleus","level":3,"score":0.5119150876998901},{"id":"https://openalex.org/C2777093970","wikidata":"https://www.wikidata.org/wiki/Q169342","display_name":"Retina","level":2,"score":0.4971654713153839},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3645791709423065},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3429808020591736},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.3382643461227417},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3347480893135071},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001369","descriptor_name":"Axons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D001369","descriptor_name":"Axons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D001369","descriptor_name":"Axons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D002415","descriptor_name":"Cats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002415","descriptor_name":"Cats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002415","descriptor_name":"Cats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005074","descriptor_name":"Evoked Potentials, Visual","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D005074","descriptor_name":"Evoked Potentials, Visual","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D005074","descriptor_name":"Evoked Potentials, Visual","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D005829","descriptor_name":"Geniculate Bodies","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D005829","descriptor_name":"Geniculate Bodies","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D005829","descriptor_name":"Geniculate Bodies","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D007395","descriptor_name":"Interneurons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D007395","descriptor_name":"Interneurons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D007395","descriptor_name":"Interneurons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008959","descriptor_name":"Models, Neurological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008959","descriptor_name":"Models, Neurological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008959","descriptor_name":"Models, Neurological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010775","descriptor_name":"Photic Stimulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010775","descriptor_name":"Photic Stimulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010775","descriptor_name":"Photic Stimulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012165","descriptor_name":"Retinal Ganglion Cells","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D012165","descriptor_name":"Retinal Ganglion Cells","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D012165","descriptor_name":"Retinal Ganglion Cells","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D014793","descriptor_name":"Visual Cortex","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D014793","descriptor_name":"Visual Cortex","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D014793","descriptor_name":"Visual Cortex","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D014795","descriptor_name":"Visual Pathways","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D014795","descriptor_name":"Visual Pathways","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D014795","descriptor_name":"Visual Pathways","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055592","descriptor_name":"Biophysical Phenomena","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055592","descriptor_name":"Biophysical Phenomena","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055592","descriptor_name":"Biophysical Phenomena","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1371/journal.pcbi.1004929","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1004929","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1004929&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},{"id":"pmid:27203421","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/27203421","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS computational biology","raw_type":null},{"id":"pmh:oai:brage.bibsys.no:11250/2405019","is_oa":true,"landing_page_url":"http://hdl.handle.net/11250/2405019","pdf_url":null,"source":{"id":"https://openalex.org/S4306400255","display_name":"BIBSYS Brage (BIBSYS (Norway))","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I173212132","host_organization_name":"Vilnius University","host_organization_lineage":["https://openalex.org/I173212132"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Journal article"},{"id":"pmh:oai:doaj.org/article:9e85389b7d2d47eda2952be09fa73c0a","is_oa":true,"landing_page_url":"https://doaj.org/article/9e85389b7d2d47eda2952be09fa73c0a","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Computational Biology, Vol 12, Iss 5, p e1004929 (2016)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4874694","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4874694","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Comput Biol","raw_type":"Text"},{"id":"pmh:oai:www.duo.uio.no:10852/52462","is_oa":true,"landing_page_url":"http://hdl.handle.net/10852/52462","pdf_url":null,"source":{"id":"https://openalex.org/S4306401716","display_name":"Duo Research Archive (University of Oslo)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I184942183","host_organization_name":"University of Oslo","host_organization_lineage":["https://openalex.org/I184942183"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"1553-734X","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1371/journal.pcbi.1004929","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1004929","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1004929&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.44999998807907104,"display_name":"Good health and well-being"}],"awards":[{"id":"https://openalex.org/G1095062678","display_name":null,"funder_award_id":"604102","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G1288628409","display_name":"Service Annotations for User Interface Composition","funder_award_id":"216699","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G3450683625","display_name":null,"funder_award_id":"216699","funder_id":"https://openalex.org/F4320323299","funder_display_name":"Norges Forskningsr\u00e5d"},{"id":"https://openalex.org/G3829048491","display_name":null,"funder_award_id":"FP7/2007-2013","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G5593277320","display_name":null,"funder_award_id":"2007-2013","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G5702163051","display_name":null,"funder_award_id":"FP7/2007","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G8750896698","display_name":null,"funder_award_id":"604102","funder_id":"https://openalex.org/F4320334960","funder_display_name":"Seventh Framework Programme"}],"funders":[{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320323299","display_name":"Norges Forskningsr\u00e5d","ror":"https://ror.org/00epmv149"},{"id":"https://openalex.org/F4320334960","display_name":"Seventh Framework Programme","ror":"https://ror.org/00k4n6c32"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2394883599.pdf","grobid_xml":"https://content.openalex.org/works/W2394883599.grobid-xml"},"referenced_works_count":91,"referenced_works":["https://openalex.org/W173956165","https://openalex.org/W560233946","https://openalex.org/W575576090","https://openalex.org/W602834913","https://openalex.org/W648800387","https://openalex.org/W1034309145","https://openalex.org/W1514161587","https://openalex.org/W1552428214","https://openalex.org/W1659146383","https://openalex.org/W1665004120","https://openalex.org/W1761768872","https://openalex.org/W1843427334","https://openalex.org/W1850148372","https://openalex.org/W1929757528","https://openalex.org/W1955585424","https://openalex.org/W1965673217","https://openalex.org/W1968459684","https://openalex.org/W1969043989","https://openalex.org/W1970039327","https://openalex.org/W1970716201","https://openalex.org/W1975543446","https://openalex.org/W1979793766","https://openalex.org/W1981239280","https://openalex.org/W1982112664","https://openalex.org/W1986458819","https://openalex.org/W1993962620","https://openalex.org/W1994262842","https://openalex.org/W1997709511","https://openalex.org/W1999098023","https://openalex.org/W1999134832","https://openalex.org/W1999675973","https://openalex.org/W2001635516","https://openalex.org/W2006222581","https://openalex.org/W2011494925","https://openalex.org/W2011997028","https://openalex.org/W2012587612","https://openalex.org/W2015253730","https://openalex.org/W2017682809","https://openalex.org/W2018809434","https://openalex.org/W2020547409","https://openalex.org/W2023539733","https://openalex.org/W2024997165","https://openalex.org/W2028595898","https://openalex.org/W2032053368","https://openalex.org/W2035773029","https://openalex.org/W2036035699","https://openalex.org/W2038545718","https://openalex.org/W2041461999","https://openalex.org/W2050996013","https://openalex.org/W2059715474","https://openalex.org/W2060866741","https://openalex.org/W2064886678","https://openalex.org/W2068970713","https://openalex.org/W2076891899","https://openalex.org/W2079728426","https://openalex.org/W2079949692","https://openalex.org/W2085740291","https://openalex.org/W2086336925","https://openalex.org/W2087861759","https://openalex.org/W2090016678","https://openalex.org/W2091181932","https://openalex.org/W2091496561","https://openalex.org/W2094439882","https://openalex.org/W2103113084","https://openalex.org/W2105977945","https://openalex.org/W2108692322","https://openalex.org/W2110285260","https://openalex.org/W2112014690","https://openalex.org/W2116454469","https://openalex.org/W2136812849","https://openalex.org/W2136987517","https://openalex.org/W2137303544","https://openalex.org/W2155170674","https://openalex.org/W2155706938","https://openalex.org/W2165586822","https://openalex.org/W2169252706","https://openalex.org/W2170154592","https://openalex.org/W2187173114","https://openalex.org/W2278231432","https://openalex.org/W2336431928","https://openalex.org/W2365924967","https://openalex.org/W2411223414","https://openalex.org/W2412343049","https://openalex.org/W2460840553","https://openalex.org/W2491111449","https://openalex.org/W2585198072","https://openalex.org/W2788026236","https://openalex.org/W4214775604","https://openalex.org/W4307697508","https://openalex.org/W6630888863","https://openalex.org/W7053011049"],"related_works":["https://openalex.org/W3104551098","https://openalex.org/W2972627647","https://openalex.org/W1987677640","https://openalex.org/W2059720077","https://openalex.org/W11242434","https://openalex.org/W2051551602","https://openalex.org/W2542327379","https://openalex.org/W2024821972","https://openalex.org/W2166777364","https://openalex.org/W2155258764"],"abstract_inverted_index":{"Despite":[0],"its":[1],"prominent":[2],"placement":[3],"between":[4],"the":[5,12,16,19,29,33,43,118,181,190,225,244,248,250,252,254,261,264,272,281],"retina":[6],"and":[7,27,51,74,113,125,148,175,196,200,296],"primary":[8],"visual":[9,14,30,133,304],"cortex":[10],"in":[11,25,143,159,164,238,280],"early":[13],"pathway,":[15],"role":[17,270],"of":[18,42,87,103,108,121,146,167,194,211,224,227,271,298,303],"dorsal":[20],"lateral":[21],"geniculate":[22],"nucleus":[23],"(dLGN)":[24],"molding":[26],"regulating":[28],"signals":[31,305],"entering":[32],"brain":[34],"is":[35,46,284],"still":[36],"poorly":[37],"understood.":[38],"A":[39],"striking":[40],"feature":[41],"dLGN":[44,282],"circuit":[45,283],"that":[47,130],"relay":[48],"cells":[49],"(RCs)":[50],"interneurons":[52],"(INs)":[53],"form":[54],"so-called":[55,82,127],"triadic":[56,83,111,206,294],"synapses,":[57],"where":[58],"an":[59,77,96],"IN":[60,212],"dendritic":[61],"terminal":[62],"can":[63],"be":[64],"simultaneously":[65],"postsynaptic":[66],"to":[67,76,156,169,217,230,241,260,278,285,307],"a":[68,88,144,220,268],"retinal":[69],"ganglion":[70],"cell":[71],"(GC)":[72],"input":[73,228],"presynaptic":[75],"RC":[78,255],"dendrite,":[79],"allowing":[80],"for":[81,95,139,172,289],"inhibition.":[84],"Taking":[85],"advantage":[86],"recently":[89],"developed":[90],"biophysically":[91],"detailed":[92],"multicompartmental":[93],"model":[94,151,182],"IN,":[97],"we":[98],"here":[99],"investigate":[100,126,179],"putative":[101],"effects":[102],"these":[104],"different":[105,273],"inhibitory":[106,274],"actions":[107,275],"INs,":[109,197],"i.e.,":[110],"inhibition":[112,207,236],"standard":[114],"axonal":[115,235],"inhibition,":[116,251],"on":[117],"response":[119,186],"properties":[120,187],"RCs.":[122,176],"We":[123,177],"compute":[124],"area-response":[128],"curves,":[129],"is,":[131],"trial-averaged":[132],"spike":[134],"responses":[135,168,199],"vs.":[136],"spot":[137],"size,":[138],"circular":[140],"flashing":[141],"spots":[142],"network":[145],"RCs":[147,195,279],"INs.":[149],"The":[150],"parameters":[152],"are":[153],"grossly":[154],"tuned":[155],"give":[157],"results":[158],"qualitative":[160],"accordance":[161],"with":[162],"previous":[163],"vivo":[165],"data":[166],"such":[170,188],"stimuli":[171],"cat":[173],"GCs":[174],"particularly":[178],"how":[180],"ingredients":[183],"affect":[184,243],"salient":[185],"as":[189],"receptive-field":[191,245],"center":[192,246,256],"size":[193,257],"maximal":[198],"center-surround":[201],"antagonisms.":[202],"For":[203],"example,":[204],"while":[205],"not":[208],"involving":[209],"firing":[210],"action":[213],"potentials":[214],"was":[215,237],"found":[216,240],"provide":[218,286],"only":[219],"non-linear":[221],"gain":[222,291],"control":[223,292],"conversion":[226],"spikes":[229,232],"output":[231],"by":[233],"RCs,":[234],"contrast":[239],"substantially":[242],"size:":[247],"larger":[249],"more":[253],"shrinks":[258],"compared":[259],"GC":[262],"providing":[263],"feedforward":[265],"excitation.":[266],"Thus,":[267],"possible":[269],"from":[276],"INs":[277],"separate":[287],"mechanisms":[288],"overall":[290],"(direct":[293],"inhibition)":[295,302],"regulation":[297],"spatial":[299],"resolution":[300],"(axonal":[301],"sent":[306],"cortex.":[308]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":3},{"year":2018,"cited_by_count":6}],"updated_date":"2026-05-06T08:25:59.206177","created_date":"2025-10-10T00:00:00"}