{"id":"https://openalex.org/W2308233814","doi":"https://doi.org/10.1371/journal.pcbi.1004823","title":"A New Fiji-Based Algorithm That Systematically Quantifies Nine Synaptic Parameters Provides Insights into Drosophila NMJ Morphometry","display_name":"A New Fiji-Based Algorithm That Systematically Quantifies Nine Synaptic Parameters Provides Insights into Drosophila NMJ Morphometry","publication_year":2016,"publication_date":"2016-03-21","ids":{"openalex":"https://openalex.org/W2308233814","doi":"https://doi.org/10.1371/journal.pcbi.1004823","mag":"2308233814","pmid":"https://pubmed.ncbi.nlm.nih.gov/26998933"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pcbi.1004823","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1004823","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1004823&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1004823&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5089279799","display_name":"Bonnie Nijhof","orcid":null},"institutions":[{"id":"https://openalex.org/I145872427","display_name":"Radboud University Nijmegen","ror":"https://ror.org/016xsfp80","country_code":"NL","type":"education","lineage":["https://openalex.org/I145872427"]},{"id":"https://openalex.org/I2802934949","display_name":"Radboud University Medical Center","ror":"https://ror.org/05wg1m734","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2802934949"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Bonnie Nijhof","raw_affiliation_strings":["Department of Human Genetics, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, the Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Human Genetics, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, the Netherlands","institution_ids":["https://openalex.org/I145872427","https://openalex.org/I2802934949"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061907990","display_name":"Anna Castells\u2010Nobau","orcid":"https://orcid.org/0000-0002-6024-8353"},"institutions":[{"id":"https://openalex.org/I145872427","display_name":"Radboud University Nijmegen","ror":"https://ror.org/016xsfp80","country_code":"NL","type":"education","lineage":["https://openalex.org/I145872427"]},{"id":"https://openalex.org/I2802934949","display_name":"Radboud University Medical Center","ror":"https://ror.org/05wg1m734","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2802934949"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Anna Castells-Nobau","raw_affiliation_strings":["Department of Human Genetics, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, the Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Human Genetics, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, the Netherlands","institution_ids":["https://openalex.org/I145872427","https://openalex.org/I2802934949"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055259269","display_name":"Louis Wolf","orcid":null},"institutions":[{"id":"https://openalex.org/I145872427","display_name":"Radboud University Nijmegen","ror":"https://ror.org/016xsfp80","country_code":"NL","type":"education","lineage":["https://openalex.org/I145872427"]},{"id":"https://openalex.org/I2802934949","display_name":"Radboud University Medical Center","ror":"https://ror.org/05wg1m734","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2802934949"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Louis Wolf","raw_affiliation_strings":["Microscopical Imaging Centre (MIC), Radboud University Medical Center, Nijmegen, the Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Microscopical Imaging Centre (MIC), Radboud University Medical Center, Nijmegen, the Netherlands","institution_ids":["https://openalex.org/I145872427","https://openalex.org/I2802934949"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042160383","display_name":"Jolanda M. Scheffer-de Gooyert","orcid":null},"institutions":[{"id":"https://openalex.org/I145872427","display_name":"Radboud University Nijmegen","ror":"https://ror.org/016xsfp80","country_code":"NL","type":"education","lineage":["https://openalex.org/I145872427"]},{"id":"https://openalex.org/I2802934949","display_name":"Radboud University Medical Center","ror":"https://ror.org/05wg1m734","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2802934949"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Jolanda M. Scheffer-de Gooyert","raw_affiliation_strings":["Department of Human Genetics, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, the Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Human Genetics, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, the Netherlands","institution_ids":["https://openalex.org/I145872427","https://openalex.org/I2802934949"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Ignacio Monedero","orcid":null},"institutions":[{"id":"https://openalex.org/I102134673","display_name":"Link\u00f6ping University","ror":"https://ror.org/05ynxx418","country_code":"SE","type":"education","lineage":["https://openalex.org/I102134673"]},{"id":"https://openalex.org/I63634437","display_name":"Universidad Aut\u00f3noma de Madrid","ror":"https://ror.org/01cby8j38","country_code":"ES","type":"education","lineage":["https://openalex.org/I63634437"]}],"countries":["ES","SE"],"is_corresponding":false,"raw_author_name":"Ignacio Monedero","raw_affiliation_strings":["Department of Biology, Universidad Aut\u00f3noma de Madrid, Madrid, Spain","Department of Clinical and Experimental Medicine, Link\u00f6ping University, Link\u00f6ping, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Universidad Aut\u00f3noma de Madrid, Madrid, Spain","institution_ids":["https://openalex.org/I63634437"]},{"raw_affiliation_string":"Department of Clinical and Experimental Medicine, Link\u00f6ping University, Link\u00f6ping, Sweden","institution_ids":["https://openalex.org/I102134673"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009822494","display_name":"Laura Torroja","orcid":"https://orcid.org/0000-0001-6939-6259"},"institutions":[{"id":"https://openalex.org/I63634437","display_name":"Universidad Aut\u00f3noma de Madrid","ror":"https://ror.org/01cby8j38","country_code":"ES","type":"education","lineage":["https://openalex.org/I63634437"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Laura Torroja","raw_affiliation_strings":["Department of Biology, Universidad Aut\u00f3noma de Madrid, Madrid, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Universidad Aut\u00f3noma de Madrid, Madrid, Spain","institution_ids":["https://openalex.org/I63634437"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044693419","display_name":"Llu\u00eds Coromina","orcid":"https://orcid.org/0000-0003-0769-0633"},"institutions":[{"id":"https://openalex.org/I251424209","display_name":"Universitat de Girona","ror":"https://ror.org/01xdxns91","country_code":"ES","type":"education","lineage":["https://openalex.org/I251424209"]},{"id":"https://openalex.org/I4210154894","display_name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Epidemiolog\u00eda y Salud P\u00fablica","ror":"https://ror.org/050q0kv47","country_code":"ES","type":"facility","lineage":["https://openalex.org/I2801357902","https://openalex.org/I4210115082","https://openalex.org/I4210154894","https://openalex.org/I4387152914"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Lluis Coromina","raw_affiliation_strings":["Research Group on Statistics, Econometrics and Health (GRECS) and CIBER of Epidemiology and Public Health (CIBERESP), University of Girona, Girona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Group on Statistics, Econometrics and Health (GRECS) and CIBER of Epidemiology and Public Health (CIBERESP), University of Girona, Girona, Spain","institution_ids":["https://openalex.org/I251424209","https://openalex.org/I4210154894"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081003438","display_name":"Jeroen van der Laak","orcid":"https://orcid.org/0000-0001-7982-0754"},"institutions":[{"id":"https://openalex.org/I145872427","display_name":"Radboud University Nijmegen","ror":"https://ror.org/016xsfp80","country_code":"NL","type":"education","lineage":["https://openalex.org/I145872427"]},{"id":"https://openalex.org/I2802934949","display_name":"Radboud University Medical Center","ror":"https://ror.org/05wg1m734","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2802934949"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Jeroen A. W. M. van der Laak","raw_affiliation_strings":["Department of Pathology, Radboud University Medical Center, Nijmegen, the Netherlands","Microscopical Imaging Centre (MIC), Radboud University Medical Center, Nijmegen, the Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Radboud University Medical Center, Nijmegen, the Netherlands","institution_ids":["https://openalex.org/I145872427","https://openalex.org/I2802934949"]},{"raw_affiliation_string":"Microscopical Imaging Centre (MIC), Radboud University Medical Center, Nijmegen, the Netherlands","institution_ids":["https://openalex.org/I145872427","https://openalex.org/I2802934949"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5025826954","display_name":"Annette Schenck","orcid":"https://orcid.org/0000-0002-6918-3314"},"institutions":[{"id":"https://openalex.org/I145872427","display_name":"Radboud University Nijmegen","ror":"https://ror.org/016xsfp80","country_code":"NL","type":"education","lineage":["https://openalex.org/I145872427"]},{"id":"https://openalex.org/I2802934949","display_name":"Radboud University Medical Center","ror":"https://ror.org/05wg1m734","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2802934949"]}],"countries":["NL"],"is_corresponding":true,"raw_author_name":"Annette Schenck","raw_affiliation_strings":["Department of Human Genetics, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, the Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Human Genetics, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, the Netherlands","institution_ids":["https://openalex.org/I145872427","https://openalex.org/I2802934949"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5025826954"],"corresponding_institution_ids":["https://openalex.org/I145872427","https://openalex.org/I2802934949"],"apc_list":{"value":2655,"currency":"USD","value_usd":2655},"apc_paid":{"value":2655,"currency":"USD","value_usd":2655},"fwci":3.5566,"has_fulltext":true,"cited_by_count":69,"citation_normalized_percentile":{"value":0.9293374,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"12","issue":"3","first_page":"e1004823","last_page":"e1004823"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10423","display_name":"Neurobiology and Insect Physiology Research","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10423","display_name":"Neurobiology and Insect Physiology Research","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12813","display_name":"Plant and Biological Electrophysiology Studies","score":0.9732999801635742,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9490000009536743,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/drosophila","display_name":"Drosophila (subgenus)","score":0.6426604986190796},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.5195701122283936},{"id":"https://openalex.org/keywords/neuromuscular-junction","display_name":"Neuromuscular junction","score":0.4987819194793701},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.4728700816631317},{"id":"https://openalex.org/keywords/developmental-biology","display_name":"Developmental biology","score":0.4377082586288452},{"id":"https://openalex.org/keywords/evolutionary-biology","display_name":"Evolutionary biology","score":0.4186495542526245},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.3881898820400238},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.3302651047706604},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.2999836206436157},{"id":"https://openalex.org/keywords/cell-biology","display_name":"Cell biology","score":0.275024950504303},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.1672622263431549},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.07220569252967834}],"concepts":[{"id":"https://openalex.org/C2776041557","wikidata":"https://www.wikidata.org/wiki/Q3715451","display_name":"Drosophila (subgenus)","level":3,"score":0.6426604986190796},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5195701122283936},{"id":"https://openalex.org/C2777240379","wikidata":"https://www.wikidata.org/wiki/Q776995","display_name":"Neuromuscular junction","level":2,"score":0.4987819194793701},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.4728700816631317},{"id":"https://openalex.org/C183074962","wikidata":"https://www.wikidata.org/wiki/Q213713","display_name":"Developmental biology","level":2,"score":0.4377082586288452},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.4186495542526245},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.3881898820400238},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3302651047706604},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.2999836206436157},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.275024950504303},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.1672622263431549},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.07220569252967834}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004330","descriptor_name":"Drosophila","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D004330","descriptor_name":"Drosophila","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D004330","descriptor_name":"Drosophila","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D004330","descriptor_name":"Drosophila","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D007090","descriptor_name":"Image Interpretation, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007090","descriptor_name":"Image Interpretation, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007090","descriptor_name":"Image Interpretation, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007090","descriptor_name":"Image Interpretation, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008953","descriptor_name":"Models, Anatomic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008953","descriptor_name":"Models, Anatomic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008953","descriptor_name":"Models, Anatomic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008953","descriptor_name":"Models, Anatomic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008959","descriptor_name":"Models, Neurological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008959","descriptor_name":"Models, Neurological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008959","descriptor_name":"Models, Neurological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008959","descriptor_name":"Models, Neurological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009469","descriptor_name":"Neuromuscular Junction","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D009469","descriptor_name":"Neuromuscular Junction","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D009469","descriptor_name":"Neuromuscular Junction","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D009469","descriptor_name":"Neuromuscular Junction","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D057225","descriptor_name":"Data Mining","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057225","descriptor_name":"Data Mining","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057225","descriptor_name":"Data Mining","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057225","descriptor_name":"Data Mining","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":13,"locations":[{"id":"doi:10.1371/journal.pcbi.1004823","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1004823","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1004823&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},{"id":"pmid:26998933","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26998933","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS computational biology","raw_type":null},{"id":"pmh:oai:dugi-doc:10256/14041","is_oa":true,"landing_page_url":"http://hdl.handle.net/10256/14041","pdf_url":null,"source":{"id":"https://openalex.org/S4306401633","display_name":"Universitat de Girona Digital Repository (Universitat de Girona)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I251424209","host_organization_name":"Universitat de Girona","host_organization_lineage":["https://openalex.org/I251424209"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:ru:oai:repository.ubn.ru.nl:2066/165707","is_oa":true,"landing_page_url":"http://hdl.handle.net/2066/165707","pdf_url":"http://hdl.handle.net/2066/165707","source":{"id":"https://openalex.org/S4306401843","display_name":"Data Archiving and Networked Services (DANS)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1322597698","host_organization_name":"Royal Netherlands Academy of Arts and Sciences","host_organization_lineage":["https://openalex.org/I1322597698"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Plos Computational Biology, 12, 1 - 25","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:DiVA.org:liu-127269","is_oa":true,"landing_page_url":"http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-127269","pdf_url":null,"source":{"id":"https://openalex.org/S4306401559","display_name":"KTH Publication Database DiVA (KTH Royal Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:RePEc:plo:pcbi00:1004823","is_oa":false,"landing_page_url":"https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1004823","pdf_url":null,"source":{"id":"https://openalex.org/S4306401271","display_name":"RePEc: Research Papers in Economics","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I77793887","host_organization_name":"Federal Reserve Bank of St. Louis","host_organization_lineage":["https://openalex.org/I77793887"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"},{"id":"pmh:oai:doaj.org/article:f3679944e9ac45838e96d1074f2a481f","is_oa":true,"landing_page_url":"https://doaj.org/article/f3679944e9ac45838e96d1074f2a481f","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Computational Biology, Vol 12, Iss 3, p e1004823 (2016)","raw_type":"article"},{"id":"pmh:oai:figshare.com:article/3128347","is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/A_New_Fiji_Based_Algorithm_That_Systematically_Quantifies_Nine_Synaptic_Parameters_Provides_Insights_into_i_Drosophila_i_NMJ_Morphometry/3128347","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"},{"id":"pmh:oai:pubmedcentral.nih.gov:4801422","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4801422","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Comput Biol","raw_type":"Text"},{"id":"pmh:oai:recercat.cat:2072/319612","is_oa":true,"landing_page_url":"http://hdl.handle.net/2072/319612","pdf_url":null,"source":{"id":"https://openalex.org/S4306402147","display_name":"RECERCAT (Consorci de Serveis Universitaris de Catalunya)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210090028","host_organization_name":"Consorci de Serveis Universitaris de Catalunya","host_organization_lineage":["https://openalex.org/I4210090028"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:recercat.cat:2072/372764","is_oa":true,"landing_page_url":"http://hdl.handle.net/2072/372764","pdf_url":null,"source":{"id":"https://openalex.org/S4306402147","display_name":"RECERCAT (Consorci de Serveis Universitaris de Catalunya)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210090028","host_organization_name":"Consorci de Serveis Universitaris de Catalunya","host_organization_lineage":["https://openalex.org/I4210090028"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:repositorio.uam.es:10486/679222","is_oa":true,"landing_page_url":"http://hdl.handle.net/10486/679222","pdf_url":null,"source":{"id":"https://openalex.org/S4306400964","display_name":"Biblos-e Archivo (Universidad Aut\u00f3noma de Madrid)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I63634437","host_organization_name":"Universidad Aut\u00f3noma de Madrid","host_organization_lineage":["https://openalex.org/I63634437"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:repository.ubn.ru.nl:2066/165707","is_oa":false,"landing_page_url":"https://hdl.handle.net/2066/165707","pdf_url":null,"source":{"id":"https://openalex.org/S4306401067","display_name":"Radboud Repository (Radboud University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I145872427","host_organization_name":"Radboud University Nijmegen","host_organization_lineage":["https://openalex.org/I145872427"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article / Letter to editor"}],"best_oa_location":{"id":"doi:10.1371/journal.pcbi.1004823","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1004823","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1004823&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Gender equality","id":"https://metadata.un.org/sdg/5","score":0.550000011920929}],"awards":[{"id":"https://openalex.org/G1148620618","display_name":null,"funder_award_id":"912-12-109","funder_id":"https://openalex.org/F4320321800","funder_display_name":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek"},{"id":"https://openalex.org/G7189394294","display_name":null,"funder_award_id":"P40 OD018537","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G8430993392","display_name":null,"funder_award_id":"917-96-346","funder_id":"https://openalex.org/F4320321800","funder_display_name":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek"}],"funders":[{"id":"https://openalex.org/F4320321013","display_name":"Radboud Universiteit","ror":"https://ror.org/016xsfp80"},{"id":"https://openalex.org/F4320321800","display_name":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek","ror":"https://ror.org/04jsz6e67"},{"id":"https://openalex.org/F4320323698","display_name":"Radboud Universitair Medisch Centrum","ror":"https://ror.org/05wg1m734"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2308233814.pdf","grobid_xml":"https://content.openalex.org/works/W2308233814.grobid-xml"},"referenced_works_count":70,"referenced_works":["https://openalex.org/W169301608","https://openalex.org/W187368791","https://openalex.org/W1488670117","https://openalex.org/W1488847214","https://openalex.org/W1528687531","https://openalex.org/W1587505135","https://openalex.org/W1594236859","https://openalex.org/W1934152683","https://openalex.org/W1976198045","https://openalex.org/W1976834667","https://openalex.org/W1979883968","https://openalex.org/W1981585359","https://openalex.org/W1983230142","https://openalex.org/W1984132311","https://openalex.org/W1987048771","https://openalex.org/W1993216598","https://openalex.org/W2004498315","https://openalex.org/W2004921550","https://openalex.org/W2012883464","https://openalex.org/W2013478045","https://openalex.org/W2014829418","https://openalex.org/W2029683101","https://openalex.org/W2031695523","https://openalex.org/W2035801011","https://openalex.org/W2036560723","https://openalex.org/W2044594834","https://openalex.org/W2044836636","https://openalex.org/W2046141144","https://openalex.org/W2046511552","https://openalex.org/W2047097851","https://openalex.org/W2048743675","https://openalex.org/W2053050328","https://openalex.org/W2061312413","https://openalex.org/W2064683298","https://openalex.org/W2066327141","https://openalex.org/W2071122929","https://openalex.org/W2078749921","https://openalex.org/W2084840477","https://openalex.org/W2090560931","https://openalex.org/W2092618028","https://openalex.org/W2099676980","https://openalex.org/W2102548112","https://openalex.org/W2103814462","https://openalex.org/W2107554012","https://openalex.org/W2108281485","https://openalex.org/W2115396712","https://openalex.org/W2118730048","https://openalex.org/W2124260943","https://openalex.org/W2124276310","https://openalex.org/W2126986198","https://openalex.org/W2137214779","https://openalex.org/W2140033867","https://openalex.org/W2146115263","https://openalex.org/W2148846435","https://openalex.org/W2150972545","https://openalex.org/W2160616996","https://openalex.org/W2163256056","https://openalex.org/W2167279371","https://openalex.org/W2175731782","https://openalex.org/W2285776971","https://openalex.org/W2308233814","https://openalex.org/W2313339984","https://openalex.org/W2582743722","https://openalex.org/W2775625538","https://openalex.org/W4200313904","https://openalex.org/W4285719527","https://openalex.org/W6644341444","https://openalex.org/W6657941571","https://openalex.org/W6746702660","https://openalex.org/W6831698578"],"related_works":["https://openalex.org/W2534156229","https://openalex.org/W4394254583","https://openalex.org/W2173880","https://openalex.org/W2220458821","https://openalex.org/W2801227923","https://openalex.org/W2908962691","https://openalex.org/W2371050059","https://openalex.org/W2806288029","https://openalex.org/W1943792583","https://openalex.org/W2133285281"],"abstract_inverted_index":{"The":[0],"morphology":[1],"of":[2,5,11,20,32,80,106,126,157,222,227,237],"synapses":[3],"is":[4,176],"central":[6],"interest":[7],"in":[8,24,167,181],"neuroscience":[9],"because":[10],"the":[12,81,89,107,131,235,238,262,269],"intimate":[13],"relation":[14],"with":[15,245],"synaptic":[16],"efficacy.":[17],"Two":[18],"decades":[19],"gene":[21],"manipulation":[22],"studies":[23,42],"different":[25,62,251],"animal":[26],"models":[27],"have":[28],"revealed":[29],"a":[30,50,55,96,113],"repertoire":[31],"molecules":[33],"that":[34,140,151,171,234,250],"contribute":[35,164],"to":[36,66,165,178,192],"synapse":[37,104],"development.":[38],"However,":[39],"since":[40],"such":[41,70],"often":[43],"assessed":[44],"only":[45,74],"one,":[46],"or":[47],"at":[48,54,268],"best":[49],"few,":[51],"morphological":[52],"features":[53],"given":[56],"synapse,":[57],"it":[58,141],"remained":[59],"unaddressed":[60],"how":[61],"structural":[63],"aspects":[64],"relate":[65],"one":[67],"another.":[68],"Furthermore,":[69],"focused":[71],"and":[72,102,136,138,147,155,162,185,199,225],"sometimes":[73],"qualitative":[75],"approaches":[76,267],"likely":[77],"left":[78],"many":[79],"more":[82],"subtle":[83],"players":[84],"unnoticed.":[85],"Here,":[86],"we":[87,211,248],"present":[88],"image":[90],"analysis":[91],"algorithm":[92],"'Drosophila_NMJ_Morphometrics',":[93],"available":[94],"as":[95],"Fiji-compatible":[97],"macro,":[98],"for":[99,122,130,144,173,264],"quantitative,":[100],"accurate":[101],"objective":[103],"morphometry":[105,266],"Drosophila":[108,271],"larval":[109],"neuromuscular":[110],"junction":[111],"(NMJ),":[112],"well-established":[114],"glutamatergic":[115],"model":[116],"synapse.":[117],"We":[118,149],"developed":[119],"this":[120],"methodology":[121],"semi-automated":[123],"multiparametric":[124],"analyses":[125,188],"NMJ":[127,216,223],"terminals":[128],"immunolabeled":[129],"commonly":[132],"used":[133],"markers":[134],"Dlg1":[135],"Brp":[137],"showed":[139],"also":[142],"works":[143],"Hrp,":[145],"Csp":[146],"Syt.":[148],"demonstrate":[150],"gender,":[152],"genetic":[153],"background":[154],"identity":[156],"abdominal":[158],"body":[159],"segment":[160],"consistently":[161],"significantly":[163],"variability":[166,180],"our":[168,232],"data,":[169],"suggesting":[170],"controlling":[172],"these":[174,255],"parameters":[175,196,236],"important":[177],"minimize":[179],"quantitative":[182],"analyses.":[183],"Correlation":[184],"principal":[186,241],"component":[187],"(PCA)":[189],"were":[190],"performed":[191],"investigate":[193],"which":[194,200],"morphometric":[195,214,257],"are":[197,202],"inter-dependent":[198],"ones":[201],"regulated":[203],"rather":[204],"independently.":[205],"Based":[206,230],"on":[207,231],"nine":[208],"acquired":[209],"parameters,":[210],"identified":[212],"five":[213],"groups:":[215],"size,":[217,220],"geometry,":[218],"muscle":[219],"number":[221,226],"islands":[224],"active":[228],"zones.":[229],"finding":[233],"first":[239],"two":[240,256],"components":[242],"hardly":[243],"correlated":[244],"each":[246],"other,":[247],"suggest":[249],"molecular":[252],"processes":[253],"underlie":[254],"groups.":[258],"Our":[259],"study":[260],"sets":[261],"stage":[263],"systems":[265],"well-studied":[270],"NMJ.":[272]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":11},{"year":2020,"cited_by_count":14},{"year":2019,"cited_by_count":8},{"year":2018,"cited_by_count":7},{"year":2017,"cited_by_count":7},{"year":2016,"cited_by_count":1}],"updated_date":"2026-07-30T17:31:21.811387","created_date":"2025-10-10T00:00:00"}