{"id":"https://openalex.org/W2262138991","doi":"https://doi.org/10.1371/journal.pcbi.1004408","title":"Detecting Horizontal Gene Transfer between Closely Related Taxa","display_name":"Detecting Horizontal Gene Transfer between Closely Related Taxa","publication_year":2015,"publication_date":"2015-10-06","ids":{"openalex":"https://openalex.org/W2262138991","doi":"https://doi.org/10.1371/journal.pcbi.1004408","mag":"2262138991","pmid":"https://pubmed.ncbi.nlm.nih.gov/26439115"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pcbi.1004408","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1004408","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1004408&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1004408&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5066616376","display_name":"Orit Adato","orcid":"https://orcid.org/0000-0002-2135-8947"},"institutions":[{"id":"https://openalex.org/I91203450","display_name":"University of Haifa","ror":"https://ror.org/02f009v59","country_code":"IL","type":"education","lineage":["https://openalex.org/I91203450"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Orit Adato","raw_affiliation_strings":["Department of Evolutionary Biology, University of Haifa, Haifa, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Evolutionary Biology, University of Haifa, Haifa, Israel","institution_ids":["https://openalex.org/I91203450"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083089371","display_name":"Noga Ninyo","orcid":null},"institutions":[{"id":"https://openalex.org/I91203450","display_name":"University of Haifa","ror":"https://ror.org/02f009v59","country_code":"IL","type":"education","lineage":["https://openalex.org/I91203450"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Noga Ninyo","raw_affiliation_strings":["Department of Evolutionary Biology, University of Haifa, Haifa, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Evolutionary Biology, University of Haifa, Haifa, Israel","institution_ids":["https://openalex.org/I91203450"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015777117","display_name":"Uri Gophna","orcid":"https://orcid.org/0000-0001-5129-5652"},"institutions":[{"id":"https://openalex.org/I16391192","display_name":"Tel Aviv University","ror":"https://ror.org/04mhzgx49","country_code":"IL","type":"education","lineage":["https://openalex.org/I16391192"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Uri Gophna","raw_affiliation_strings":["Department of Molecular Microbiology and Biotechnology Tel Aviv University, Tel-Aviv, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Microbiology and Biotechnology Tel Aviv University, Tel-Aviv, Israel","institution_ids":["https://openalex.org/I16391192"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5063493591","display_name":"Sagi Snir","orcid":"https://orcid.org/0000-0001-5833-7659"},"institutions":[{"id":"https://openalex.org/I91203450","display_name":"University of Haifa","ror":"https://ror.org/02f009v59","country_code":"IL","type":"education","lineage":["https://openalex.org/I91203450"]}],"countries":["IL"],"is_corresponding":true,"raw_author_name":"Sagi Snir","raw_affiliation_strings":["Department of Evolutionary Biology, University of Haifa, Haifa, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Evolutionary Biology, University of Haifa, Haifa, Israel","institution_ids":["https://openalex.org/I91203450"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5063493591"],"corresponding_institution_ids":["https://openalex.org/I91203450"],"apc_list":{"value":2655,"currency":"USD","value_usd":2655},"apc_paid":{"value":2655,"currency":"USD","value_usd":2655},"fwci":2.5598,"has_fulltext":true,"cited_by_count":73,"citation_normalized_percentile":{"value":0.90115395,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"11","issue":"10","first_page":"e1004408","last_page":"e1004408"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.994700014591217,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.9905999898910522,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/horizontal-gene-transfer","display_name":"Horizontal gene transfer","score":0.8759063482284546},{"id":"https://openalex.org/keywords/synteny","display_name":"Synteny","score":0.848231315612793},{"id":"https://openalex.org/keywords/phylogenetic-tree","display_name":"Phylogenetic tree","score":0.7301985621452332},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.7147400379180908},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.6475844979286194},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.6088327765464783},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.5429423451423645},{"id":"https://openalex.org/keywords/phylogenetics","display_name":"Phylogenetics","score":0.4751741290092468},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.4201244115829468},{"id":"https://openalex.org/keywords/evolutionary-biology","display_name":"Evolutionary biology","score":0.35126280784606934}],"concepts":[{"id":"https://openalex.org/C92938381","wikidata":"https://www.wikidata.org/wiki/Q83185","display_name":"Horizontal gene transfer","level":4,"score":0.8759063482284546},{"id":"https://openalex.org/C53702515","wikidata":"https://www.wikidata.org/wiki/Q971246","display_name":"Synteny","level":4,"score":0.848231315612793},{"id":"https://openalex.org/C193252679","wikidata":"https://www.wikidata.org/wiki/Q242125","display_name":"Phylogenetic tree","level":3,"score":0.7301985621452332},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7147400379180908},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.6475844979286194},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.6088327765464783},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5429423451423645},{"id":"https://openalex.org/C90132467","wikidata":"https://www.wikidata.org/wiki/Q171184","display_name":"Phylogenetics","level":3,"score":0.4751741290092468},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4201244115829468},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.35126280784606934}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D008957","descriptor_name":"Models, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008957","descriptor_name":"Models, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008957","descriptor_name":"Models, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010802","descriptor_name":"Phylogeny","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010802","descriptor_name":"Phylogeny","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010802","descriptor_name":"Phylogeny","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016680","descriptor_name":"Genome, Bacterial","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D016680","descriptor_name":"Genome, Bacterial","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D016680","descriptor_name":"Genome, Bacterial","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D019143","descriptor_name":"Evolution, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019143","descriptor_name":"Evolution, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019143","descriptor_name":"Evolution, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D022761","descriptor_name":"Gene Transfer, Horizontal","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D022761","descriptor_name":"Gene Transfer, Horizontal","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D022761","descriptor_name":"Gene Transfer, Horizontal","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D026801","descriptor_name":"Synteny","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D026801","descriptor_name":"Synteny","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D026801","descriptor_name":"Synteny","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1371/journal.pcbi.1004408","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1004408","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1004408&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},{"id":"pmid:26439115","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26439115","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS computational biology","raw_type":null},{"id":"pmh:oai:doaj.org/article:287068c6c4854d69bf2e1022ed49b8b4","is_oa":true,"landing_page_url":"https://doaj.org/article/287068c6c4854d69bf2e1022ed49b8b4","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Computational Biology, Vol 11, Iss 10, p e1004408 (2015)","raw_type":"article"},{"id":"pmh:oai:europepmc.org:3575894","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4595140","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:figshare.com:article/1566111","is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/_Detecting_Horizontal_Gene_Transfer_between_Closely_Related_Taxa_/1566111","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"}],"best_oa_location":{"id":"doi:10.1371/journal.pcbi.1004408","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1004408","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1004408&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Industry, innovation and infrastructure","score":0.6100000143051147,"id":"https://metadata.un.org/sdg/9"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320322252","display_name":"Israel Science Foundation","ror":"https://ror.org/04sazxf24"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2262138991.pdf","grobid_xml":"https://content.openalex.org/works/W2262138991.grobid-xml"},"referenced_works_count":79,"referenced_works":["https://openalex.org/W1504977545","https://openalex.org/W1525734744","https://openalex.org/W1529802779","https://openalex.org/W1579352620","https://openalex.org/W1587558271","https://openalex.org/W1623420165","https://openalex.org/W1776424232","https://openalex.org/W1958274537","https://openalex.org/W1971158963","https://openalex.org/W1982901388","https://openalex.org/W1988001504","https://openalex.org/W1993695973","https://openalex.org/W1993713389","https://openalex.org/W2000175834","https://openalex.org/W2009219904","https://openalex.org/W2017470100","https://openalex.org/W2017500947","https://openalex.org/W2021416330","https://openalex.org/W2024811317","https://openalex.org/W2027031393","https://openalex.org/W2040745248","https://openalex.org/W2044719651","https://openalex.org/W2060247879","https://openalex.org/W2060640325","https://openalex.org/W2064452752","https://openalex.org/W2074572936","https://openalex.org/W2077043540","https://openalex.org/W2082521980","https://openalex.org/W2098558111","https://openalex.org/W2106882534","https://openalex.org/W2107387420","https://openalex.org/W2107903949","https://openalex.org/W2108035844","https://openalex.org/W2110667602","https://openalex.org/W2111211467","https://openalex.org/W2111775329","https://openalex.org/W2113174377","https://openalex.org/W2113824405","https://openalex.org/W2116502500","https://openalex.org/W2116992659","https://openalex.org/W2119490692","https://openalex.org/W2121166240","https://openalex.org/W2124817677","https://openalex.org/W2127688908","https://openalex.org/W2129081404","https://openalex.org/W2129538546","https://openalex.org/W2129771418","https://openalex.org/W2132553324","https://openalex.org/W2135869163","https://openalex.org/W2138952930","https://openalex.org/W2140647036","https://openalex.org/W2143518155","https://openalex.org/W2146622826","https://openalex.org/W2151003257","https://openalex.org/W2153139855","https://openalex.org/W2155066423","https://openalex.org/W2156133126","https://openalex.org/W2157622572","https://openalex.org/W2159058143","https://openalex.org/W2163191830","https://openalex.org/W2164898486","https://openalex.org/W2168453028","https://openalex.org/W2469442455","https://openalex.org/W2475881817","https://openalex.org/W2496945004","https://openalex.org/W2801982793","https://openalex.org/W2892113722","https://openalex.org/W4205910801","https://openalex.org/W4211040199","https://openalex.org/W4233815609","https://openalex.org/W4239871258","https://openalex.org/W4241196009","https://openalex.org/W4249875616","https://openalex.org/W4302165970","https://openalex.org/W4376561447","https://openalex.org/W4388212639","https://openalex.org/W6948047203","https://openalex.org/W7061596628","https://openalex.org/W7066511990"],"related_works":["https://openalex.org/W2131180151","https://openalex.org/W2037172645","https://openalex.org/W4243565069","https://openalex.org/W2106726141","https://openalex.org/W1984420856","https://openalex.org/W2119233950","https://openalex.org/W2174809885","https://openalex.org/W2086569686","https://openalex.org/W2043760664","https://openalex.org/W3016599224"],"abstract_inverted_index":{"Horizontal":[0],"gene":[1,123,168],"transfer":[2,5],"(HGT),":[3],"the":[4,17,33,56,63,90,114,119,149,156,188,209,238],"of":[6,19,92,121,193,240],"genetic":[7,14],"material":[8],"between":[9,47,79,137],"organisms,":[10],"is":[11,53,59,66,72,98,179],"crucial":[12],"for":[13],"innovation":[15],"and":[16,62,95,100,129,176,198,233],"evolution":[18],"genome":[20],"architecture.":[21],"Existing":[22],"HGT":[23,46,78,135,183,213],"detection":[24,214],"algorithms":[25],"rely":[26],"on":[27,113,148,163],"a":[28,73,105,122,159,181,191,217,247],"strong":[29],"phylogenetic":[30,57],"signal":[31,58],"distinguishing":[32],"transferred":[34,145],"sequence":[35,165],"from":[36,124],"ancestral":[37],"(vertically":[38],"derived)":[39],"genes":[40,146,245],"in":[41,76,85,246],"its":[42,125],"recipient":[43],"genome.":[44],"Detecting":[45],"closely":[48,138],"related":[49,139],"species":[50,81],"or":[51,82],"strains":[52,97,197],"challenging,":[54],"as":[55],"usually":[60],"weak":[61],"nucleotide":[64],"composition":[65],"normally":[67],"nearly":[68],"identical.":[69],"Nevertheless,":[70],"there":[71],"great":[74],"importance":[75],"detecting":[77,241],"congeneric":[80],"strains,":[83],"especially":[84],"clinical":[86],"microbiology,":[87],"where":[88],"understanding":[89],"emergence":[91],"new":[93,228],"virulent":[94],"drug-resistant":[96],"crucial,":[99],"often":[101],"time-sensitive.":[102],"We":[103,185,206],"developed":[104],"novel,":[106],"self-contained":[107],"technique":[108,189],"named":[109],"Near":[110],"HGT,":[111],"based":[112,147,162],"synteny":[115,175],"index,":[116],"to":[117,132,173,190,211,237],"measure":[118],"divergence":[120],"native":[126],"genomic":[127],"environment":[128],"used":[130],"it":[131],"identify":[133],"candidate":[134,144],"events":[136],"strains.":[140],"The":[141],"method":[142,210],"confirms":[143],"constant":[150],"relative":[151],"mutability":[152,177],"(CRM).":[153],"Using":[154],"CRM,":[155],"algorithm":[157,229],"assigns":[158],"confidence":[160],"score":[161],"\"unusual\"":[164],"divergence.":[166],"A":[167],"exhibiting":[169],"exceptional":[170],"deviations":[171],"according":[172],"both":[174],"criteria,":[178],"considered":[180],"validated":[182],"product.":[184],"first":[186],"employed":[187],"set":[192],"three":[194],"E.":[195],"coli":[196],"detected":[199],"several":[200],"highly":[201],"probable":[202],"horizontally":[203],"acquired":[204,244],"genes.":[205],"then":[207],"compared":[208],"existing":[212],"tools":[215],"using":[216],"larger":[218],"strain":[219],"data":[220],"set.":[221],"When":[222],"combined":[223],"with":[224],"additional":[225],"approaches":[226],"our":[227],"provides":[230],"richer":[231],"picture":[232],"brings":[234],"us":[235],"closer":[236],"goal":[239],"all":[242],"newly":[243],"particular":[248],"strain.":[249]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":9},{"year":2024,"cited_by_count":10},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":12},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":7},{"year":2019,"cited_by_count":8},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":9},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":1}],"updated_date":"2026-05-28T09:10:13.091523","created_date":"2025-10-10T00:00:00"}