{"id":"https://openalex.org/W2039281962","doi":"https://doi.org/10.1371/journal.pcbi.1003787","title":"Dynamic Mechanisms of Neocortical Focal Seizure Onset","display_name":"Dynamic Mechanisms of Neocortical Focal Seizure Onset","publication_year":2014,"publication_date":"2014-08-14","ids":{"openalex":"https://openalex.org/W2039281962","doi":"https://doi.org/10.1371/journal.pcbi.1003787","mag":"2039281962","pmid":"https://pubmed.ncbi.nlm.nih.gov/25122455"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pcbi.1003787","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1003787","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1003787&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Computational Biology","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1003787&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5010837788","display_name":"Yujiang Wang","orcid":"https://orcid.org/0000-0002-4847-6273"},"institutions":[{"id":"https://openalex.org/I84884186","display_name":"Newcastle University","ror":"https://ror.org/01kj2bm70","country_code":"GB","type":"education","lineage":["https://openalex.org/I84884186"]},{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Yujiang Wang","raw_affiliation_strings":["Manchester Interdisciplinary Biocentre, The University of Manchester, Manchester, United Kingdom; School of Computing Science, Newcastle University, Newcastle upon Tyne, United Kingdom","School of Computing Science, Newcastle University, Newcastle upon Tyne, United Kingdom","Manchester Interdisciplinary Biocentre, The University of Manchester, Manchester, United Kingdom"],"affiliations":[{"raw_affiliation_string":"Manchester Interdisciplinary Biocentre, The University of Manchester, Manchester, United Kingdom; School of Computing Science, Newcastle University, Newcastle upon Tyne, United Kingdom","institution_ids":[]},{"raw_affiliation_string":"School of Computing Science, Newcastle University, Newcastle upon Tyne, United Kingdom","institution_ids":["https://openalex.org/I84884186"]},{"raw_affiliation_string":"Manchester Interdisciplinary Biocentre, The University of Manchester, Manchester, United Kingdom","institution_ids":["https://openalex.org/I28407311"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024052002","display_name":"Marc Goodfellow","orcid":"https://orcid.org/0000-0002-7282-7280"},"institutions":[{"id":"https://openalex.org/I23923803","display_name":"University of Exeter","ror":"https://ror.org/03yghzc09","country_code":"GB","type":"education","lineage":["https://openalex.org/I23923803"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Marc Goodfellow","raw_affiliation_strings":["College of Engineering, Mathematics and Physical Sciences, University of Exeter, Exeter, United Kingdom"],"affiliations":[{"raw_affiliation_string":"College of Engineering, Mathematics and Physical Sciences, University of Exeter, Exeter, United Kingdom","institution_ids":["https://openalex.org/I23923803"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020252837","display_name":"Peter N. Taylor","orcid":"https://orcid.org/0000-0003-2144-9838"},"institutions":[{"id":"https://openalex.org/I84884186","display_name":"Newcastle University","ror":"https://ror.org/01kj2bm70","country_code":"GB","type":"education","lineage":["https://openalex.org/I84884186"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Peter Neal Taylor","raw_affiliation_strings":["School of Computing Science, Newcastle University, Newcastle upon Tyne, United Kingdom"],"affiliations":[{"raw_affiliation_string":"School of Computing Science, Newcastle University, Newcastle upon Tyne, United Kingdom","institution_ids":["https://openalex.org/I84884186"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5024260303","display_name":"Gerold Baier","orcid":"https://orcid.org/0000-0002-2540-3100"},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Gerold Baier","raw_affiliation_strings":["Cell and Developmental Biology, University College London, London, United Kingdom"],"affiliations":[{"raw_affiliation_string":"Cell and Developmental Biology, University College London, London, United Kingdom","institution_ids":["https://openalex.org/I45129253"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5024260303"],"corresponding_institution_ids":["https://openalex.org/I45129253"],"apc_list":{"value":2655,"currency":"USD","value_usd":2655},"apc_paid":{"value":1681,"currency":"EUR","value_usd":1812},"fwci":3.7619,"has_fulltext":true,"cited_by_count":58,"citation_normalized_percentile":{"value":0.93587522,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":100},"biblio":{"volume":"10","issue":"8","first_page":"e1003787","last_page":"e1003787"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":0.9979000091552734,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11513","display_name":"stochastic dynamics and bifurcation","score":0.9973000288009644,"subfield":{"id":"https://openalex.org/subfields/3109","display_name":"Statistical and Nonlinear Physics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.6854598522186279},{"id":"https://openalex.org/keywords/mesoscopic-physics","display_name":"Mesoscopic physics","score":0.5603994727134705},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.3692997694015503},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.350172221660614},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.3098949193954468}],"concepts":[{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.6854598522186279},{"id":"https://openalex.org/C177731217","wikidata":"https://www.wikidata.org/wiki/Q2622244","display_name":"Mesoscopic physics","level":2,"score":0.5603994727134705},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3692997694015503},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.350172221660614},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.3098949193954468},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D002540","descriptor_name":"Cerebral Cortex","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D002540","descriptor_name":"Cerebral Cortex","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D002540","descriptor_name":"Cerebral Cortex","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004827","descriptor_name":"Epilepsy","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D004827","descriptor_name":"Epilepsy","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D004827","descriptor_name":"Epilepsy","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008959","descriptor_name":"Models, Neurological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008959","descriptor_name":"Models, Neurological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008959","descriptor_name":"Models, Neurological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012640","descriptor_name":"Seizures","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D012640","descriptor_name":"Seizures","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D012640","descriptor_name":"Seizures","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":10,"locations":[{"id":"doi:10.1371/journal.pcbi.1003787","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1003787","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1003787&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Computational Biology","raw_type":"journal-article"},{"id":"pmid:25122455","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25122455","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS computational biology","raw_type":null},{"id":"pmh:oai:ore.exeter.ac.uk:10871/20162","is_oa":false,"landing_page_url":"http://hdl.handle.net/10871/20162","pdf_url":null,"source":{"id":"https://openalex.org/S4306401998","display_name":"Open Research Exeter (University of Exeter)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I23923803","host_organization_name":"University of Exeter","host_organization_lineage":["https://openalex.org/I23923803"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.773.1574","is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.773.1574","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/d8/3e/pcbi.1003787.PMC4133160.pdf","raw_type":"text"},{"id":"pmh:oai:RePEc:plo:pcbi00:1003787","is_oa":false,"landing_page_url":"https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1003787","pdf_url":null,"source":{"id":"https://openalex.org/S4306401271","display_name":"RePEc: Research Papers in Economics","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I77793887","host_organization_name":"Federal Reserve Bank of St. Louis","host_organization_lineage":["https://openalex.org/I77793887"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"},{"id":"pmh:oai:doaj.org/article:92a67c48c4bb44feb8f7c390d8424442","is_oa":true,"landing_page_url":"https://doaj.org/article/92a67c48c4bb44feb8f7c390d8424442","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Computational Biology, Vol 10, Iss 8, p e1003787 (2014)","raw_type":"article"},{"id":"pmh:oai:eprint.ncl.ac.uk:205983","is_oa":false,"landing_page_url":null,"pdf_url":null,"source":{"id":"https://openalex.org/S4306402485","display_name":"Newcastle University ePrints (Newcastle Univesity)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I84884186","host_organization_name":"Newcastle University","host_organization_lineage":["https://openalex.org/I84884186"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":""},{"id":"pmh:oai:eprints.ucl.ac.uk.OAI2:1443263","is_oa":false,"landing_page_url":"https://discovery.ucl.ac.uk/id/eprint/1443263/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400024","display_name":"UCL Discovery (University College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I45129253","host_organization_name":"University College London","host_organization_lineage":["https://openalex.org/I45129253"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"   PLoS Comput Biol , 10  (8)    , Article e1003787. (2014)      ","raw_type":"Article"},{"id":"pmh:oai:europepmc.org:3105957","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4133160","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:figshare.com:article/1140305","is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/_Dynamic_Mechanisms_of_Neocortical_Focal_Seizure_Onset_/1140305","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"}],"best_oa_location":{"id":"doi:10.1371/journal.pcbi.1003787","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1003787","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1003787&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Computational Biology","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1934935867","display_name":null,"funder_award_id":"Engineering and Physical Sciences R","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"}],"funders":[{"id":"https://openalex.org/F4320332167","display_name":"Directorate for Biological Sciences","ror":"https://ror.org/001xhss06"},{"id":"https://openalex.org/F4320334627","display_name":"Engineering and Physical Sciences Research Council","ror":"https://ror.org/0439y7842"},{"id":"https://openalex.org/F4320334629","display_name":"Biotechnology and Biological Sciences Research Council","ror":"https://ror.org/00cwqg982"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2039281962.pdf","grobid_xml":"https://content.openalex.org/works/W2039281962.grobid-xml"},"referenced_works_count":85,"referenced_works":["https://openalex.org/W45867273","https://openalex.org/W106698915","https://openalex.org/W1556669719","https://openalex.org/W1560895878","https://openalex.org/W1582051163","https://openalex.org/W1904506299","https://openalex.org/W1970554538","https://openalex.org/W1970604942","https://openalex.org/W1974192412","https://openalex.org/W1977922270","https://openalex.org/W1978174497","https://openalex.org/W1978650677","https://openalex.org/W1979308352","https://openalex.org/W1985983039","https://openalex.org/W1988730455","https://openalex.org/W1991227621","https://openalex.org/W1991695159","https://openalex.org/W1992147695","https://openalex.org/W1992476998","https://openalex.org/W2004547695","https://openalex.org/W2008518032","https://openalex.org/W2009578021","https://openalex.org/W2012958662","https://openalex.org/W2016354087","https://openalex.org/W2016767879","https://openalex.org/W2019232485","https://openalex.org/W2019689276","https://openalex.org/W2025604508","https://openalex.org/W2032263100","https://openalex.org/W2032407678","https://openalex.org/W2032689087","https://openalex.org/W2036682006","https://openalex.org/W2037852104","https://openalex.org/W2037902675","https://openalex.org/W2053168002","https://openalex.org/W2058933456","https://openalex.org/W2059004036","https://openalex.org/W2063962699","https://openalex.org/W2065309771","https://openalex.org/W2066045752","https://openalex.org/W2066765190","https://openalex.org/W2067891729","https://openalex.org/W2068487107","https://openalex.org/W2071928207","https://openalex.org/W2075436929","https://openalex.org/W2080808870","https://openalex.org/W2081133991","https://openalex.org/W2084818694","https://openalex.org/W2085677445","https://openalex.org/W2086728580","https://openalex.org/W2090063036","https://openalex.org/W2093285596","https://openalex.org/W2096827445","https://openalex.org/W2102952547","https://openalex.org/W2103934527","https://openalex.org/W2105425384","https://openalex.org/W2105504969","https://openalex.org/W2107974789","https://openalex.org/W2108397312","https://openalex.org/W2109930285","https://openalex.org/W2112227389","https://openalex.org/W2115726932","https://openalex.org/W2116925697","https://openalex.org/W2117469172","https://openalex.org/W2123503734","https://openalex.org/W2123553271","https://openalex.org/W2131582127","https://openalex.org/W2139755184","https://openalex.org/W2140591465","https://openalex.org/W2147223467","https://openalex.org/W2147576365","https://openalex.org/W2150310369","https://openalex.org/W2150497419","https://openalex.org/W2155148112","https://openalex.org/W2160184536","https://openalex.org/W2162640192","https://openalex.org/W2163691442","https://openalex.org/W2167226244","https://openalex.org/W2170088360","https://openalex.org/W2313560363","https://openalex.org/W2325746253","https://openalex.org/W2402340177","https://openalex.org/W4237066238","https://openalex.org/W4237239156","https://openalex.org/W6643865377"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2899084033","https://openalex.org/W2748952813","https://openalex.org/W2935759653","https://openalex.org/W3105167352","https://openalex.org/W54078636","https://openalex.org/W2954470139","https://openalex.org/W1501425562","https://openalex.org/W2902782467","https://openalex.org/W2790535609"],"abstract_inverted_index":{"Recent":[0],"experimental":[1,57,196],"and":[2,17,28,58,107,160,197],"clinical":[3,59,198],"studies":[4],"have":[5,156],"provided":[6],"diverse":[7],"insight":[8],"into":[9,32],"the":[10,53,71,110,131,184,193],"mechanisms":[11,69,106,132,186],"of":[12,26,44,67,73,133,192],"human":[13],"focal":[14,74,87,92,97,122,153],"seizure":[15],"initiation":[16],"propagation.":[18],"Often":[19],"these":[20,104],"findings":[21,60],"exist":[22],"at":[23],"different":[24,157],"scales":[25],"observation,":[27],"are":[29],"not":[30],"reconciled":[31],"a":[33,39,77,145,174],"common":[34],"understanding.":[35],"Here":[36],"we":[37,102,117],"develop":[38],"new,":[40],"multiscale":[41],"mathematical":[42],"model":[43,54,100,164],"cortical":[45],"electric":[46],"activity":[47],"with":[48],"realistic":[49],"mesoscopic":[50],"connectivity.":[51],"Relating":[52],"dynamics":[55],"to":[56,63,126,138,183,189],"leads":[61],"us":[62],"propose":[64],"three":[65,81,111],"classes":[66,82,112],"dynamical":[68,185],"for":[70],"onset":[72,105,134],"seizures":[75,123,154],"in":[76,173],"unified":[78],"framework.":[79],"These":[80],"are:":[83],"(i)":[84],"globally":[85,90],"induced":[86,96],"seizures;":[88,93],"(ii)":[89],"supported":[91],"(iii)":[94],"locally":[95],"seizures.":[98],"Using":[99],"simulations":[101],"illustrate":[103],"show":[108],"how":[109],"can":[113,169],"be":[114,136,171],"distinguished.":[115],"Specifically,":[116],"find":[118],"that":[119,151,166],"although":[120,152],"all":[121],"typically":[124],"appear":[125],"arise":[127],"from":[128],"localised":[129,140],"tissue,":[130],"could":[135],"due":[137],"either":[139],"processes":[141,143],"or":[142],"on":[144],"larger":[146],"spatial":[147],"scale.":[148],"We":[149],"conclude":[150],"might":[155],"patient-specific":[158],"aetiologies":[159],"electrographic":[161],"signatures,":[162],"our":[163],"suggests":[165],"dynamically":[167],"they":[168],"still":[170],"classified":[172],"clinically":[175],"useful":[176],"way.":[177],"Additionally,":[178],"this":[179],"novel":[180],"classification":[181],"according":[182],"is":[187],"able":[188],"resolve":[190],"some":[191],"previously":[194],"conflicting":[195],"findings.":[199]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":13},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-04-10T15:06:20.359241","created_date":"2025-10-10T00:00:00"}
