{"id":"https://openalex.org/W2057245137","doi":"https://doi.org/10.1371/journal.pcbi.1002937","title":"Trade-off between Multiple Constraints Enables Simultaneous Formation of Modules and Hubs in Neural Systems","display_name":"Trade-off between Multiple Constraints Enables Simultaneous Formation of Modules and Hubs in Neural Systems","publication_year":2013,"publication_date":"2013-03-07","ids":{"openalex":"https://openalex.org/W2057245137","doi":"https://doi.org/10.1371/journal.pcbi.1002937","mag":"2057245137","pmid":"https://pubmed.ncbi.nlm.nih.gov/23505352"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pcbi.1002937","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1002937","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1002937&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Computational Biology","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1002937&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100650506","display_name":"Yuhan Chen","orcid":"https://orcid.org/0000-0003-0695-0317"},"institutions":[{"id":"https://openalex.org/I141568987","display_name":"Hong Kong Baptist University","ror":"https://ror.org/0145fw131","country_code":"HK","type":"education","lineage":["https://openalex.org/I141568987"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Yuhan Chen","raw_affiliation_strings":["Department of Physics, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China","Centre for Nonlinear Studies, and Beijing-Hong Kong-Singapore Joint Centre for Nonlinear and Complex Systems (Hong Kong), Institute of Computational and Theoretical Studies, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physics, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China","institution_ids":["https://openalex.org/I141568987"]},{"raw_affiliation_string":"Centre for Nonlinear Studies, and Beijing-Hong Kong-Singapore Joint Centre for Nonlinear and Complex Systems (Hong Kong), Institute of Computational and Theoretical Studies, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China","institution_ids":["https://openalex.org/I141568987"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010336803","display_name":"Sheng-Jun Wang","orcid":"https://orcid.org/0000-0003-1051-6150"},"institutions":[{"id":"https://openalex.org/I141568987","display_name":"Hong Kong Baptist University","ror":"https://ror.org/0145fw131","country_code":"HK","type":"education","lineage":["https://openalex.org/I141568987"]},{"id":"https://openalex.org/I88830068","display_name":"Shaanxi Normal University","ror":"https://ror.org/0170z8493","country_code":"CN","type":"education","lineage":["https://openalex.org/I88830068"]}],"countries":["CN","HK"],"is_corresponding":false,"raw_author_name":"Shengjun Wang","raw_affiliation_strings":["Centre for Nonlinear Studies, and Beijing-Hong Kong-Singapore Joint Centre for Nonlinear and Complex Systems (Hong Kong), Institute of Computational and Theoretical Studies, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China","Department of Physics, Shaanxi Normal University, Xi'An, Shaanxi Province, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Nonlinear Studies, and Beijing-Hong Kong-Singapore Joint Centre for Nonlinear and Complex Systems (Hong Kong), Institute of Computational and Theoretical Studies, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China","institution_ids":["https://openalex.org/I141568987"]},{"raw_affiliation_string":"Department of Physics, Shaanxi Normal University, Xi'An, Shaanxi Province, China","institution_ids":["https://openalex.org/I88830068"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045659246","display_name":"Claus C. Hilgetag","orcid":"https://orcid.org/0000-0003-2129-8910"},"institutions":[{"id":"https://openalex.org/I4210108711","display_name":"University Medical Center Hamburg-Eppendorf","ror":"https://ror.org/01zgy1s35","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]},{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]},{"id":"https://openalex.org/I193619901","display_name":"Constructor University","ror":"https://ror.org/02yrs2n53","country_code":"DE","type":"education","lineage":["https://openalex.org/I193619901"]},{"id":"https://openalex.org/I159176309","display_name":"Universit\u00e4t Hamburg","ror":"https://ror.org/00g30e956","country_code":"DE","type":"education","lineage":["https://openalex.org/I159176309"]}],"countries":["DE","US"],"is_corresponding":false,"raw_author_name":"Claus C. Hilgetag","raw_affiliation_strings":["Department of Computational Neuroscience, University Medical Center Eppendorf, Hamburg, Germany","Department of Health Sciences, Boston University, Boston, Massachusetts, United States of America","School of Engineering and Science, Jacobs University Bremen, Bremen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computational Neuroscience, University Medical Center Eppendorf, Hamburg, Germany","institution_ids":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]},{"raw_affiliation_string":"Department of Health Sciences, Boston University, Boston, Massachusetts, United States of America","institution_ids":["https://openalex.org/I111088046"]},{"raw_affiliation_string":"School of Engineering and Science, Jacobs University Bremen, Bremen, Germany","institution_ids":["https://openalex.org/I193619901"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5029297296","display_name":"Changsong Zhou","orcid":"https://orcid.org/0000-0002-4130-0216"},"institutions":[{"id":"https://openalex.org/I141568987","display_name":"Hong Kong Baptist University","ror":"https://ror.org/0145fw131","country_code":"HK","type":"education","lineage":["https://openalex.org/I141568987"]},{"id":"https://openalex.org/I4210139958","display_name":"Beijing Computational Science Research Center","ror":"https://ror.org/04tavf782","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210139958"]}],"countries":["CN","HK"],"is_corresponding":true,"raw_author_name":"Changsong Zhou","raw_affiliation_strings":["Beijing Computational Science Research Center, Beijing, People's Republic of China","Centre for Nonlinear Studies, and Beijing-Hong Kong-Singapore Joint Centre for Nonlinear and Complex Systems (Hong Kong), Institute of Computational and Theoretical Studies, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China","Department of Physics, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China","Research Centre, HKBU Institute of Research and Continuing Education, Virtual University Park Building, South Area Hi-tech Industrial Park, Shenzhen, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beijing Computational Science Research Center, Beijing, People's Republic of China","institution_ids":["https://openalex.org/I4210139958"]},{"raw_affiliation_string":"Centre for Nonlinear Studies, and Beijing-Hong Kong-Singapore Joint Centre for Nonlinear and Complex Systems (Hong Kong), Institute of Computational and Theoretical Studies, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China","institution_ids":["https://openalex.org/I141568987"]},{"raw_affiliation_string":"Department of Physics, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China","institution_ids":["https://openalex.org/I141568987"]},{"raw_affiliation_string":"Research Centre, HKBU Institute of Research and Continuing Education, Virtual University Park Building, South Area Hi-tech Industrial Park, Shenzhen, China","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5029297296"],"corresponding_institution_ids":["https://openalex.org/I141568987","https://openalex.org/I4210139958"],"apc_list":{"value":2655,"currency":"USD","value_usd":2655},"apc_paid":{"value":2655,"currency":"USD","value_usd":2655},"fwci":4.9232,"has_fulltext":true,"cited_by_count":125,"citation_normalized_percentile":{"value":0.95745668,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":100},"biblio":{"volume":"9","issue":"3","first_page":"e1002937","last_page":"e1002937"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":0.9902999997138977,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10676","display_name":"Genetics, Aging, and Longevity in Model Organisms","score":0.9818000197410583,"subfield":{"id":"https://openalex.org/subfields/1302","display_name":"Aging"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/modular-design","display_name":"Modular design","score":0.6515642404556274},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6496647596359253},{"id":"https://openalex.org/keywords/network-topology","display_name":"Network topology","score":0.5760881304740906},{"id":"https://openalex.org/keywords/artificial-neural-network","display_name":"Artificial neural network","score":0.5756409168243408},{"id":"https://openalex.org/keywords/topology","display_name":"Topology (electrical circuits)","score":0.5660850405693054},{"id":"https://openalex.org/keywords/cluster-analysis","display_name":"Cluster analysis","score":0.4439358711242676},{"id":"https://openalex.org/keywords/distributed-computing","display_name":"Distributed computing","score":0.4107985198497772},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.3357333838939667},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.18628740310668945},{"id":"https://openalex.org/keywords/computer-network","display_name":"Computer network","score":0.14879077672958374}],"concepts":[{"id":"https://openalex.org/C101468663","wikidata":"https://www.wikidata.org/wiki/Q1620158","display_name":"Modular design","level":2,"score":0.6515642404556274},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6496647596359253},{"id":"https://openalex.org/C199845137","wikidata":"https://www.wikidata.org/wiki/Q145490","display_name":"Network topology","level":2,"score":0.5760881304740906},{"id":"https://openalex.org/C50644808","wikidata":"https://www.wikidata.org/wiki/Q192776","display_name":"Artificial neural network","level":2,"score":0.5756409168243408},{"id":"https://openalex.org/C184720557","wikidata":"https://www.wikidata.org/wiki/Q7825049","display_name":"Topology (electrical circuits)","level":2,"score":0.5660850405693054},{"id":"https://openalex.org/C73555534","wikidata":"https://www.wikidata.org/wiki/Q622825","display_name":"Cluster analysis","level":2,"score":0.4439358711242676},{"id":"https://openalex.org/C120314980","wikidata":"https://www.wikidata.org/wiki/Q180634","display_name":"Distributed computing","level":1,"score":0.4107985198497772},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.3357333838939667},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.18628740310668945},{"id":"https://openalex.org/C31258907","wikidata":"https://www.wikidata.org/wiki/Q1301371","display_name":"Computer network","level":1,"score":0.14879077672958374},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0},{"id":"https://openalex.org/C114614502","wikidata":"https://www.wikidata.org/wiki/Q76592","display_name":"Combinatorics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008251","descriptor_name":"Macaca","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008251","descriptor_name":"Macaca","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008251","descriptor_name":"Macaca","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008959","descriptor_name":"Models, Neurological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008959","descriptor_name":"Models, Neurological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008959","descriptor_name":"Models, Neurological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009415","descriptor_name":"Nerve Net","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009415","descriptor_name":"Nerve Net","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009415","descriptor_name":"Nerve Net","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017173","descriptor_name":"Caenorhabditis elegans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017173","descriptor_name":"Caenorhabditis elegans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017173","descriptor_name":"Caenorhabditis elegans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":7,"locations":[{"id":"doi:10.1371/journal.pcbi.1002937","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1002937","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1002937&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Computational Biology","raw_type":"journal-article"},{"id":"pmid:23505352","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23505352","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS computational biology","raw_type":null},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.812.1636","is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.812.1636","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/f8/e8/pcbi.1002937.PMC3591279.pdf","raw_type":"text"},{"id":"pmh:oai:doaj.org/article:8688b4ba785147fbbaa2dc50b1955e14","is_oa":true,"landing_page_url":"https://doaj.org/article/8688b4ba785147fbbaa2dc50b1955e14","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Computational Biology, Vol 9, Iss 3, p e1002937 (2013)","raw_type":"article"},{"id":"pmh:oai:europepmc.org:2596550","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3591279","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:figshare.com:article/646816","is_oa":true,"landing_page_url":"https://figshare.com/articles/Trade_off_between_Multiple_Constraints_Enables_Simultaneous_Formation_of_Modules_and_Hubs_in_Neural_Systems__/646816","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"},{"id":"pmh:oai:repository.hkbu.edu.hk:phys_ja-1092","is_oa":false,"landing_page_url":"https://repository.hkbu.edu.hk/phys_ja/93","pdf_url":null,"source":{"id":"https://openalex.org/S4377196872","display_name":"HKBU Institutional Repository (Hong Kong Baptist University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I141568987","host_organization_name":"Hong Kong Baptist University","host_organization_lineage":["https://openalex.org/I141568987"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Department of Physics Journal Articles","raw_type":"text"}],"best_oa_location":{"id":"doi:10.1371/journal.pcbi.1002937","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1002937","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1002937&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Computational Biology","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G4700397894","display_name":"\u51e0\u4f55\u7a7a\u95f4\u4e2d\u590d\u6742\u7f51\u7edc\u7ed3\u6784\u7684\u5f62\u6210\u673a\u5236\u63a2\u8ba8\uff1a\u590d\u6742\u795e\u7ecf\u7f51\u7edc\u7684\u591a\u91cd\u7ea6\u675f\u4f18\u5316\u7814\u7a76","funder_award_id":"11275027","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G4751113764","display_name":"\u81ea\u9002\u5e94\u7f51\u7edc\u7684\u540c\u6b65\u53ca\u5176\u7ed3\u6784\u6f14\u5316\u7814\u7a76","funder_award_id":"11005047","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320320955","display_name":"Hong Kong Baptist University","ror":"https://ror.org/0145fw131"},{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2057245137.pdf","grobid_xml":"https://content.openalex.org/works/W2057245137.grobid-xml"},"referenced_works_count":113,"referenced_works":["https://openalex.org/W1509741329","https://openalex.org/W1526844937","https://openalex.org/W1585488465","https://openalex.org/W1602141137","https://openalex.org/W1673584506","https://openalex.org/W1904905451","https://openalex.org/W1933848166","https://openalex.org/W1963595563","https://openalex.org/W1965886953","https://openalex.org/W1968941013","https://openalex.org/W1970434141","https://openalex.org/W1971421925","https://openalex.org/W1972986697","https://openalex.org/W1973474605","https://openalex.org/W1974049455","https://openalex.org/W1974764791","https://openalex.org/W1979235369","https://openalex.org/W1979426401","https://openalex.org/W1983485726","https://openalex.org/W1983537704","https://openalex.org/W1987924998","https://openalex.org/W1993673892","https://openalex.org/W1998071216","https://openalex.org/W1998446689","https://openalex.org/W1999653836","https://openalex.org/W2000042664","https://openalex.org/W2001915338","https://openalex.org/W2006312249","https://openalex.org/W2009281907","https://openalex.org/W2018045523","https://openalex.org/W2021687531","https://openalex.org/W2024633374","https://openalex.org/W2026384313","https://openalex.org/W2029109606","https://openalex.org/W2030363891","https://openalex.org/W2033078279","https://openalex.org/W2036473961","https://openalex.org/W2040092971","https://openalex.org/W2040711722","https://openalex.org/W2041951497","https://openalex.org/W2044078323","https://openalex.org/W2049570813","https://openalex.org/W2053816989","https://openalex.org/W2061099285","https://openalex.org/W2061976757","https://openalex.org/W2063251739","https://openalex.org/W2064125324","https://openalex.org/W2064440086","https://openalex.org/W2073017605","https://openalex.org/W2074993220","https://openalex.org/W2075496760","https://openalex.org/W2078393476","https://openalex.org/W2079598623","https://openalex.org/W2080105404","https://openalex.org/W2080512970","https://openalex.org/W2084585676","https://openalex.org/W2085989895","https://openalex.org/W2088430597","https://openalex.org/W2089458547","https://openalex.org/W2094017021","https://openalex.org/W2094344877","https://openalex.org/W2095491050","https://openalex.org/W2098580305","https://openalex.org/W2098923623","https://openalex.org/W2109273473","https://openalex.org/W2112090702","https://openalex.org/W2112151839","https://openalex.org/W2115748265","https://openalex.org/W2117415070","https://openalex.org/W2118050239","https://openalex.org/W2118128753","https://openalex.org/W2118323338","https://openalex.org/W2120895215","https://openalex.org/W2124637492","https://openalex.org/W2124953625","https://openalex.org/W2127389037","https://openalex.org/W2128314959","https://openalex.org/W2129211577","https://openalex.org/W2130040193","https://openalex.org/W2131215403","https://openalex.org/W2133495748","https://openalex.org/W2133864523","https://openalex.org/W2138412635","https://openalex.org/W2138996400","https://openalex.org/W2139348845","https://openalex.org/W2144662207","https://openalex.org/W2145654434","https://openalex.org/W2147238273","https://openalex.org/W2148601705","https://openalex.org/W2150371779","https://openalex.org/W2152556184","https://openalex.org/W2155525875","https://openalex.org/W2158299803","https://openalex.org/W2159242554","https://openalex.org/W2159929956","https://openalex.org/W2160078357","https://openalex.org/W2160258514","https://openalex.org/W2160938187","https://openalex.org/W2162686834","https://openalex.org/W2163071595","https://openalex.org/W2163886718","https://openalex.org/W2164262344","https://openalex.org/W2165687585","https://openalex.org/W2165985389","https://openalex.org/W2168112956","https://openalex.org/W2172274087","https://openalex.org/W2989575095","https://openalex.org/W3101421424","https://openalex.org/W3103362336","https://openalex.org/W3106209931","https://openalex.org/W3124017476","https://openalex.org/W3124373653","https://openalex.org/W3210268394"],"related_works":["https://openalex.org/W2086397253","https://openalex.org/W2378076731","https://openalex.org/W4286888643","https://openalex.org/W3210795196","https://openalex.org/W2133122801","https://openalex.org/W2088988140","https://openalex.org/W600422426","https://openalex.org/W2803103875","https://openalex.org/W2103019253","https://openalex.org/W2007156430"],"abstract_inverted_index":{"The":[0,163,215,267,286],"formation":[1],"of":[2,7,43,64,104,149,159,177,183,192,212,217,224,244,259,270],"the":[3,65,68,118,122,132,137,146,152,160,190,193,206,222,237,257,283],"complex":[4,75],"network":[5,184,239],"architecture":[6],"neural":[8,51,91,130],"systems":[9],"is":[10,77],"subject":[11],"to":[12,121,189,255],"multiple":[13,262],"structural":[14],"and":[15,28,38,61,74,96,107,116,151,155,165,196,202,233,273],"functional":[16,62],"constraints.":[17],"Two":[18],"obvious":[19],"but":[20],"apparently":[21],"contradictory":[22],"constraints":[23,73,139,263,269],"are":[24,53,291,296],"low":[25],"wiring":[26,36,105,271],"cost":[27,60,106,272],"high":[29],"processing":[30,44,108,274],"efficiency,":[31,275],"characterized":[32],"by":[33,87],"short":[34],"overall":[35],"length":[37],"a":[39,56,112,169,174,210,241],"small":[40],"average":[41],"number":[42],"steps,":[45],"respectively.":[46],"Growing":[47],"evidence":[48,254],"shows":[49],"that":[50,127,289,295],"networks":[52,120,134,167],"results":[54],"from":[55,101,136,180],"trade-off":[57,260],"between":[58,70,145,261],"physical":[59],"value":[63],"topology.":[66],"However,":[67],"relationship":[69,85],"these":[71],"competing":[72],"topology":[76],"not":[78,297],"well":[79],"understood":[80],"quantitatively.":[81],"We":[82,125],"explored":[83],"this":[84],"systematically":[86],"reconstructing":[88],"two":[89,138,194,268],"known":[90],"networks,":[92],"Macaque":[93],"cortical":[94],"connectivity":[95],"C.":[97],"elegans":[98],"neuronal":[99],"connections,":[100],"combinatory":[102],"optimization":[103],"efficiency":[109],"constraints,":[110,195],"using":[111],"control":[113],"parameter":[114],"\u03b1,":[115,178],"comparing":[117],"reconstructed":[119,133,164,232],"real":[123,161,166,207,234,245,284],"networks.":[124,162,235,266,285],"found":[126],"in":[128,173,209,226,230,282],"both":[129,231],"systems,":[131],"derived":[135],"can":[140],"reveal":[141],"some":[142],"important":[143],"relations":[144],"spatial":[147,181,228],"layout":[148],"nodes":[150,218,225],"topological":[153],"connectivity,":[154],"match":[156],"several":[157],"properties":[158],"had":[168],"similar":[170],"modular":[171],"organization":[172],"broad":[175],"range":[176,211],"resulting":[179],"clustering":[182],"nodes.":[185],"Hubs":[186],"emerged":[187],"due":[188],"competition":[191],"their":[197,227],"positions":[198],"were":[199],"close":[200],"to,":[201],"partly":[203],"coincided,":[204],"with":[205,221],"hubs":[208],"\u03b1":[213],"values.":[214],"degree":[216],"was":[219],"correlated":[220],"density":[223],"neighborhood":[229],"Generally,":[236],"rebuilt":[238],"matched":[240],"significant":[242],"portion":[243],"links,":[246],"especially":[247],"short-distant":[248],"ones.":[249],"These":[250],"findings":[251],"provide":[252],"clear":[253],"support":[256],"hypothesis":[258],"on":[264],"brain":[265],"however,":[276],"cannot":[277],"explain":[278],"all":[279],"salient":[280],"features":[281],"discrepancy":[287],"suggests":[288],"there":[290],"further":[292],"relevant":[293],"factors":[294],"yet":[298],"captured":[299],"here.":[300]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":11},{"year":2024,"cited_by_count":9},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":10},{"year":2021,"cited_by_count":10},{"year":2020,"cited_by_count":13},{"year":2019,"cited_by_count":10},{"year":2018,"cited_by_count":11},{"year":2017,"cited_by_count":9},{"year":2016,"cited_by_count":15},{"year":2015,"cited_by_count":6},{"year":2014,"cited_by_count":9},{"year":2013,"cited_by_count":2}],"updated_date":"2026-01-13T01:12:25.745995","created_date":"2025-10-10T00:00:00"}