{"id":"https://openalex.org/W1969476624","doi":"https://doi.org/10.1371/journal.pcbi.1002611","title":"Why SIT Works: Normal Function Despite Typical Myofiber Pattern in Situs Inversus Totalis (SIT) Hearts Derived by Shear-induced Myofiber Reorientation","display_name":"Why SIT Works: Normal Function Despite Typical Myofiber Pattern in Situs Inversus Totalis (SIT) Hearts Derived by Shear-induced Myofiber Reorientation","publication_year":2012,"publication_date":"2012-07-26","ids":{"openalex":"https://openalex.org/W1969476624","doi":"https://doi.org/10.1371/journal.pcbi.1002611","mag":"1969476624","pmid":"https://pubmed.ncbi.nlm.nih.gov/22844239"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pcbi.1002611","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1002611","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1002611&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Computational Biology","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1002611&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5034127388","display_name":"Marieke Pluijmert","orcid":"https://orcid.org/0000-0003-2924-6891"},"institutions":[{"id":"https://openalex.org/I34352273","display_name":"Maastricht University","ror":"https://ror.org/02jz4aj89","country_code":"NL","type":"education","lineage":["https://openalex.org/I34352273"]},{"id":"https://openalex.org/I83019370","display_name":"Eindhoven University of Technology","ror":"https://ror.org/02c2kyt77","country_code":"NL","type":"education","lineage":["https://openalex.org/I83019370"]}],"countries":["NL"],"is_corresponding":true,"raw_author_name":"Marieke Pluijmert","raw_affiliation_strings":["Department of Biomedical Engineering/Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands. marieke.pluijmert@maastrichtuniversity.nl","Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands","Department of Biomedical Engineering/Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering/Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands. marieke.pluijmert@maastrichtuniversity.nl","institution_ids":["https://openalex.org/I34352273"]},{"raw_affiliation_string":"Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands","institution_ids":["https://openalex.org/I83019370"]},{"raw_affiliation_string":"Department of Biomedical Engineering/Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands","institution_ids":["https://openalex.org/I34352273"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061576167","display_name":"Wilco Kroon","orcid":null},"institutions":[{"id":"https://openalex.org/I34352273","display_name":"Maastricht University","ror":"https://ror.org/02jz4aj89","country_code":"NL","type":"education","lineage":["https://openalex.org/I34352273"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Wilco Kroon","raw_affiliation_strings":["Department of Biomedical Engineering/Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering/Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands","institution_ids":["https://openalex.org/I34352273"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101744075","display_name":"Alessandro Rossi","orcid":"https://orcid.org/0000-0002-6719-3324"},"institutions":[{"id":"https://openalex.org/I34352273","display_name":"Maastricht University","ror":"https://ror.org/02jz4aj89","country_code":"NL","type":"education","lineage":["https://openalex.org/I34352273"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Alessandro C. Rossi","raw_affiliation_strings":["Department of Biomedical Engineering/Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering/Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands","institution_ids":["https://openalex.org/I34352273"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076538820","display_name":"Peter H. M. Bovendeerd","orcid":null},"institutions":[{"id":"https://openalex.org/I83019370","display_name":"Eindhoven University of Technology","ror":"https://ror.org/02c2kyt77","country_code":"NL","type":"education","lineage":["https://openalex.org/I83019370"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Peter H. M. Bovendeerd","raw_affiliation_strings":["Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands","institution_ids":["https://openalex.org/I83019370"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5080175953","display_name":"Tammo Delhaas","orcid":"https://orcid.org/0000-0001-6897-9700"},"institutions":[{"id":"https://openalex.org/I34352273","display_name":"Maastricht University","ror":"https://ror.org/02jz4aj89","country_code":"NL","type":"education","lineage":["https://openalex.org/I34352273"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Tammo Delhaas","raw_affiliation_strings":["Department of Biomedical Engineering/Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering/Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands","institution_ids":["https://openalex.org/I34352273"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5034127388"],"corresponding_institution_ids":["https://openalex.org/I34352273","https://openalex.org/I83019370"],"apc_list":{"value":2655,"currency":"USD","value_usd":2655},"apc_paid":{"value":2655,"currency":"USD","value_usd":2655},"fwci":0.8681,"has_fulltext":true,"cited_by_count":13,"citation_normalized_percentile":{"value":0.75899216,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"8","issue":"7","first_page":"e1002611","last_page":"e1002611"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10882","display_name":"Cardiomyopathy and Myosin Studies","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10882","display_name":"Cardiomyopathy and Myosin Studies","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10821","display_name":"Cardiovascular Function and Risk Factors","score":0.996999979019165,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11677","display_name":"Congenital heart defects research","score":0.9958999752998352,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/myocyte","display_name":"Myocyte","score":0.9113689661026001},{"id":"https://openalex.org/keywords/ventricle","display_name":"Ventricle","score":0.6578123569488525},{"id":"https://openalex.org/keywords/torsion","display_name":"Torsion (gastropod)","score":0.4690960645675659},{"id":"https://openalex.org/keywords/anatomy","display_name":"Anatomy","score":0.4570879638195038},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.32430166006088257},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.2617289423942566},{"id":"https://openalex.org/keywords/cardiology","display_name":"Cardiology","score":0.23520785570144653},{"id":"https://openalex.org/keywords/cell-biology","display_name":"Cell biology","score":0.19921258091926575}],"concepts":[{"id":"https://openalex.org/C207200792","wikidata":"https://www.wikidata.org/wiki/Q428914","display_name":"Myocyte","level":2,"score":0.9113689661026001},{"id":"https://openalex.org/C2778921608","wikidata":"https://www.wikidata.org/wiki/Q2002035","display_name":"Ventricle","level":2,"score":0.6578123569488525},{"id":"https://openalex.org/C77461463","wikidata":"https://www.wikidata.org/wiki/Q7827201","display_name":"Torsion (gastropod)","level":2,"score":0.4690960645675659},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.4570879638195038},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.32430166006088257},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2617289423942566},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.23520785570144653},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.19921258091926575}],"mesh":[{"descriptor_ui":"D006321","descriptor_name":"Heart","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006321","descriptor_name":"Heart","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006321","descriptor_name":"Heart","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006352","descriptor_name":"Heart Ventricles","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D006352","descriptor_name":"Heart Ventricles","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D006352","descriptor_name":"Heart Ventricles","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008955","descriptor_name":"Models, Cardiovascular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008955","descriptor_name":"Models, Cardiovascular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008955","descriptor_name":"Models, Cardiovascular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009206","descriptor_name":"Myocardium","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D009206","descriptor_name":"Myocardium","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D009206","descriptor_name":"Myocardium","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D009210","descriptor_name":"Myofibrils","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009210","descriptor_name":"Myofibrils","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009210","descriptor_name":"Myofibrils","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D012857","descriptor_name":"Situs Inversus","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D012857","descriptor_name":"Situs Inversus","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D012857","descriptor_name":"Situs Inversus","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D014102","descriptor_name":"Torsion Abnormality","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D014102","descriptor_name":"Torsion Abnormality","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D014102","descriptor_name":"Torsion Abnormality","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D016276","descriptor_name":"Ventricular Function","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D016276","descriptor_name":"Ventricular Function","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D016276","descriptor_name":"Ventricular Function","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":7,"locations":[{"id":"doi:10.1371/journal.pcbi.1002611","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1002611","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1002611&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Computational Biology","raw_type":"journal-article"},{"id":"pmid:22844239","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22844239","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS computational biology","raw_type":null},{"id":"pmh:oai:cris.maastrichtuniversity.nl:openaire/de2cd296-fb5e-4cbf-9839-ef31c93c4db4","is_oa":true,"landing_page_url":"https://cris.maastrichtuniversity.nl/en/publications/de2cd296-fb5e-4cbf-9839-ef31c93c4db4","pdf_url":null,"source":{"id":"https://openalex.org/S4306402616","display_name":"Research Publications (Maastricht University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I34352273","host_organization_name":"Maastricht University","host_organization_lineage":["https://openalex.org/I34352273"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pluijmert, M, Kroon, W, Rossi, A C, Bovendeerd, P H M & Delhaas, T 2012, 'Why SIT Works: Normal Function Despite Typical Myofiber Pattern in Situs Inversus Totalis (SIT) Hearts Derived by Shear-induced Myofiber Reorientation', PLoS Computational Biology, vol. 8, no. 7, e1002611. https://doi.org/10.1371/journal.pcbi.1002611","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"pmh:oai:pure.tue.nl:openaire/10813833-6b75-4574-8227-d416f913de93","is_oa":true,"landing_page_url":"https://research.tue.nl/en/publications/10813833-6b75-4574-8227-d416f913de93","pdf_url":null,"source":{"id":"https://openalex.org/S4406922641","display_name":"TU/e Research Portal","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pluijmert, M H, Kroon, J W, Rossi, A C, Bovendeerd, P H M & Delhaas, T 2012, 'Why sIT works : normal function despite typical myober pattern in situs inversus totalis (SIT) hearts derived by shear-induced myrunober reorientation', PLoS Computational Biology, vol. 8, no. 7, e1002611, pp. e1002611-1/11. https://doi.org/10.1371/journal.pcbi.1002611","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:europepmc.org:2408991","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3406011","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:d8f6179c64e54c1a971dc1dff7ba74ea","is_oa":true,"landing_page_url":"https://doaj.org/article/d8f6179c64e54c1a971dc1dff7ba74ea","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Computational Biology, Vol 8, Iss 7, p e1002611 (2012)","raw_type":"article"},{"id":"pmh:tue:oai:pure.tue.nl:publications/10813833-6b75-4574-8227-d416f913de93","is_oa":true,"landing_page_url":"https://research.tue.nl/nl/publications/10813833-6b75-4574-8227-d416f913de93","pdf_url":null,"source":{"id":"https://openalex.org/S4306401843","display_name":"Data Archiving and Networked Services (DANS)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1322597698","host_organization_name":"Royal Netherlands Academy of Arts and Sciences","host_organization_lineage":["https://openalex.org/I1322597698"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Computational Biology, 8(7):e1002611, e1002611 - 1/11. Public Library of Science","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1371/journal.pcbi.1002611","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1002611","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1002611&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Computational Biology","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320323596","display_name":"Center for Translational Molecular Medicine","ror":"https://ror.org/047wvvg23"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1969476624.pdf","grobid_xml":"https://content.openalex.org/works/W1969476624.grobid-xml"},"referenced_works_count":36,"referenced_works":["https://openalex.org/W166857550","https://openalex.org/W577652691","https://openalex.org/W1584517321","https://openalex.org/W1854898238","https://openalex.org/W1942977593","https://openalex.org/W1988213453","https://openalex.org/W1994324999","https://openalex.org/W2029026638","https://openalex.org/W2058456023","https://openalex.org/W2107334229","https://openalex.org/W2110648820","https://openalex.org/W2114345285","https://openalex.org/W2115666493","https://openalex.org/W2115774646","https://openalex.org/W2124442990","https://openalex.org/W2126270248","https://openalex.org/W2129654146","https://openalex.org/W2130432285","https://openalex.org/W2130820341","https://openalex.org/W2135421935","https://openalex.org/W2135926315","https://openalex.org/W2139772545","https://openalex.org/W2144715365","https://openalex.org/W2153797429","https://openalex.org/W2156310318","https://openalex.org/W2156731876","https://openalex.org/W2156908140","https://openalex.org/W2160984036","https://openalex.org/W2161629941","https://openalex.org/W2170316549","https://openalex.org/W2170779428","https://openalex.org/W2173021326","https://openalex.org/W2415273021","https://openalex.org/W2416016907","https://openalex.org/W2421831437","https://openalex.org/W2985191761"],"related_works":["https://openalex.org/W2082860237","https://openalex.org/W2119695867","https://openalex.org/W2130076355","https://openalex.org/W1990804418","https://openalex.org/W1993764875","https://openalex.org/W2046158694","https://openalex.org/W2412210031","https://openalex.org/W3150275987","https://openalex.org/W2137589252","https://openalex.org/W2227512334"],"abstract_inverted_index":{"The":[0,169],"left":[1],"ventricle":[2],"(LV)":[3],"of":[4,59,136,148,203,249],"mammals":[5],"with":[6,199],"Situs":[7,51],"Solitus":[8],"(SS,":[9],"normal":[10,72,206],"organ":[11,60],"arrangement)":[12],"displays":[13],"hardly":[14],"any":[15],"interindividual":[16],"variation":[17,93],"in":[18,38,83,86,94,107,128,224,234],"myofiber":[19,27,36,45,69,95,105,116,125,142,146,187,209,222,251],"pattern":[20,28,96],"and":[21,44,62,118,124,151,186,190,207,221,226,238,242],"experimentally":[22,217],"determined":[23,218],"torsion.":[24],"SS":[25,130,150,227,237],"LV":[26,64,110,137,240],"has":[29],"been":[30],"suggested":[31],"to":[32,41,174],"result":[33],"from":[34,49,246],"adaptive":[35,115,250],"reorientation,":[37,143,177],"turn":[39],"leading":[40],"efficient":[42],"pump":[43,123,183],"function.":[46],"Limited":[47],"data":[48],"the":[50,74,79,108,129,166],"Inversus":[52],"Totalis":[53],"(SIT,":[54],"a":[55,133,178,200],"complete":[56],"mirror":[57],"image":[58],"anatomy":[61],"position)":[63],"demonstrated":[65],"an":[66],"essential":[67,232],"different":[68,104,153,201],"pattern,":[70],"being":[71],"at":[73,78],"apex":[75],"but":[76],"mirrored":[77,208],"base.":[80],"Considerable":[81],"differences":[82,233],"torsion":[84,214],"patterns":[85,106,147,215],"between":[87,205],"human":[88],"SIT":[89,98,109,154,159,196,213,225,239],"LVs":[90,99,228],"even":[91],"suggest":[92],"among":[97],"themselves.":[100],"We":[101],"addressed":[102],"whether":[103,119],"can":[111],"be":[112],"predicted":[113,145],"by":[114],"reorientation":[117],"they":[120],"yield":[121],"similar":[122],"function":[126,184,188,223,243],"as":[127],"LV.":[131],"With":[132],"mathematical":[134],"model":[135],"mechanics":[138],"including":[139],"shear":[140],"induced":[141],"we":[144],"one":[149],"three":[152],"LVs.":[155],"Initial":[156],"conditions":[157],"for":[158],"were":[160],"based":[161],"on":[162,165],"scarce":[163],"information":[164],"helix":[167],"angle.":[168],"transverse":[170,180],"angle":[171,181],"was":[172],"set":[173],"zero.":[175],"During":[176],"non-zero":[179],"developed,":[182],"increased,":[185],"increased":[189],"became":[191],"more":[192],"homogeneous.":[193],"Three":[194],"continuous":[195],"structures":[197],"emerged":[198],"location":[202],"transition":[204],"orientation":[210],"pattern.":[211],"Predicted":[212],"matched":[216],"ones.":[219],"Pump":[220],"are":[229],"similar,":[230],"despite":[231],"myocardial":[235],"structure.":[236],"structure":[241],"may":[244],"originate":[245],"same":[247],"processes":[248],"reorientation.":[252]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":3}],"updated_date":"2026-08-11T07:18:39.950985","created_date":"2025-10-10T00:00:00"}
