{"id":"https://openalex.org/W1994877332","doi":"https://doi.org/10.1371/journal.pcbi.1002297","title":"Information Routing Driven by Background Chatter in a Signaling Network","display_name":"Information Routing Driven by Background Chatter in a Signaling Network","publication_year":2011,"publication_date":"2011-12-08","ids":{"openalex":"https://openalex.org/W1994877332","doi":"https://doi.org/10.1371/journal.pcbi.1002297","mag":"1994877332","pmid":"https://pubmed.ncbi.nlm.nih.gov/22174668"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pcbi.1002297","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1002297","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1002297&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Computational Biology","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1002297&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5029916814","display_name":"N\u00faria Domedel-Puig","orcid":null},"institutions":[{"id":"https://openalex.org/I9617848","display_name":"Universitat Polit\u00e8cnica de Catalunya","ror":"https://ror.org/03mb6wj31","country_code":"ES","type":"education","lineage":["https://openalex.org/I9617848"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"N\u00faria Domedel-Puig","raw_affiliation_strings":["Departament de F\u00edsica i Enginyeria Nuclear, Universitat Polit\u00e8cnica de Catalunya, Terrassa, Barcelona, Spain","Departament de Fisica i Enginyeria Nuclear, Universitat Polit\u00e9cnica de Catalunya, Terrassa (Barcelona), Spain"],"affiliations":[{"raw_affiliation_string":"Departament de F\u00edsica i Enginyeria Nuclear, Universitat Polit\u00e8cnica de Catalunya, Terrassa, Barcelona, Spain","institution_ids":["https://openalex.org/I9617848"]},{"raw_affiliation_string":"Departament de Fisica i Enginyeria Nuclear, Universitat Polit\u00e9cnica de Catalunya, Terrassa (Barcelona), Spain","institution_ids":["https://openalex.org/I9617848"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043750220","display_name":"Pau Ru\u00e9","orcid":"https://orcid.org/0000-0003-3739-7999"},"institutions":[{"id":"https://openalex.org/I9617848","display_name":"Universitat Polit\u00e8cnica de Catalunya","ror":"https://ror.org/03mb6wj31","country_code":"ES","type":"education","lineage":["https://openalex.org/I9617848"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Pau Ru\u00e9","raw_affiliation_strings":["Departament de F\u00edsica i Enginyeria Nuclear, Universitat Polit\u00e8cnica de Catalunya, Terrassa, Barcelona, Spain","Departament de Fisica i Enginyeria Nuclear, Universitat Polit\u00e9cnica de Catalunya, Terrassa (Barcelona), Spain"],"affiliations":[{"raw_affiliation_string":"Departament de F\u00edsica i Enginyeria Nuclear, Universitat Polit\u00e8cnica de Catalunya, Terrassa, Barcelona, Spain","institution_ids":["https://openalex.org/I9617848"]},{"raw_affiliation_string":"Departament de Fisica i Enginyeria Nuclear, Universitat Polit\u00e9cnica de Catalunya, Terrassa (Barcelona), Spain","institution_ids":["https://openalex.org/I9617848"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035584252","display_name":"Antonio J. Pons","orcid":"https://orcid.org/0000-0002-1481-8159"},"institutions":[{"id":"https://openalex.org/I9617848","display_name":"Universitat Polit\u00e8cnica de Catalunya","ror":"https://ror.org/03mb6wj31","country_code":"ES","type":"education","lineage":["https://openalex.org/I9617848"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Antonio J. Pons","raw_affiliation_strings":["Departament de F\u00edsica i Enginyeria Nuclear, Universitat Polit\u00e8cnica de Catalunya, Terrassa, Barcelona, Spain","Departament de Fisica i Enginyeria Nuclear, Universitat Polit\u00e9cnica de Catalunya, Terrassa (Barcelona), Spain"],"affiliations":[{"raw_affiliation_string":"Departament de F\u00edsica i Enginyeria Nuclear, Universitat Polit\u00e8cnica de Catalunya, Terrassa, Barcelona, Spain","institution_ids":["https://openalex.org/I9617848"]},{"raw_affiliation_string":"Departament de Fisica i Enginyeria Nuclear, Universitat Polit\u00e9cnica de Catalunya, Terrassa (Barcelona), Spain","institution_ids":["https://openalex.org/I9617848"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5054261070","display_name":"Jordi Garc\u00eda\u2010Ojalvo","orcid":"https://orcid.org/0000-0002-3716-7520"},"institutions":[{"id":"https://openalex.org/I9617848","display_name":"Universitat Polit\u00e8cnica de Catalunya","ror":"https://ror.org/03mb6wj31","country_code":"ES","type":"education","lineage":["https://openalex.org/I9617848"]}],"countries":["ES"],"is_corresponding":true,"raw_author_name":"Jordi Garc\u00eda-Ojalvo","raw_affiliation_strings":["Departament de F\u00edsica i Enginyeria Nuclear, Universitat Polit\u00e8cnica de Catalunya, Terrassa, Barcelona, Spain","Departament de Fisica i Enginyeria Nuclear, Universitat Polit\u00e9cnica de Catalunya, Terrassa (Barcelona), Spain"],"affiliations":[{"raw_affiliation_string":"Departament de F\u00edsica i Enginyeria Nuclear, Universitat Polit\u00e8cnica de Catalunya, Terrassa, Barcelona, Spain","institution_ids":["https://openalex.org/I9617848"]},{"raw_affiliation_string":"Departament de Fisica i Enginyeria Nuclear, Universitat Polit\u00e9cnica de Catalunya, Terrassa (Barcelona), Spain","institution_ids":["https://openalex.org/I9617848"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5054261070"],"corresponding_institution_ids":["https://openalex.org/I9617848"],"apc_list":{"value":2655,"currency":"USD","value_usd":2655},"apc_paid":{"value":2655,"currency":"USD","value_usd":2655},"fwci":0.667,"has_fulltext":true,"cited_by_count":14,"citation_normalized_percentile":{"value":0.67912556,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":97},"biblio":{"volume":"7","issue":"12","first_page":"e1002297","last_page":"e1002297"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11513","display_name":"stochastic dynamics and bifurcation","score":0.9973000288009644,"subfield":{"id":"https://openalex.org/subfields/3109","display_name":"Statistical and Nonlinear Physics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/node","display_name":"Node (physics)","score":0.5693932175636292},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5447233319282532},{"id":"https://openalex.org/keywords/boolean-network","display_name":"Boolean network","score":0.5038136839866638},{"id":"https://openalex.org/keywords/signalling","display_name":"Signalling","score":0.49548184871673584},{"id":"https://openalex.org/keywords/information-processing","display_name":"Information processing","score":0.493717759847641},{"id":"https://openalex.org/keywords/information-transmission","display_name":"Information transmission","score":0.48202431201934814},{"id":"https://openalex.org/keywords/signal","display_name":"SIGNAL (programming language)","score":0.47084471583366394},{"id":"https://openalex.org/keywords/network-topology","display_name":"Network topology","score":0.46056705713272095},{"id":"https://openalex.org/keywords/network-model","display_name":"Network model","score":0.44938981533050537},{"id":"https://openalex.org/keywords/signal-processing","display_name":"Signal processing","score":0.44721508026123047},{"id":"https://openalex.org/keywords/signal-transduction","display_name":"Signal transduction","score":0.44528454542160034},{"id":"https://openalex.org/keywords/transmission","display_name":"Transmission (telecommunications)","score":0.44278639554977417},{"id":"https://openalex.org/keywords/network-dynamics","display_name":"Network dynamics","score":0.4282868802547455},{"id":"https://openalex.org/keywords/topology","display_name":"Topology (electrical circuits)","score":0.37114953994750977},{"id":"https://openalex.org/keywords/computer-network","display_name":"Computer network","score":0.2924153208732605},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.21101295948028564},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.19715973734855652},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.1856755018234253},{"id":"https://openalex.org/keywords/boolean-function","display_name":"Boolean function","score":0.17399144172668457},{"id":"https://openalex.org/keywords/cell-biology","display_name":"Cell biology","score":0.1688486635684967},{"id":"https://openalex.org/keywords/telecommunications","display_name":"Telecommunications","score":0.16496515274047852},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.1604195535182953},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.12952309846878052},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.08690515160560608}],"concepts":[{"id":"https://openalex.org/C62611344","wikidata":"https://www.wikidata.org/wiki/Q1062658","display_name":"Node (physics)","level":2,"score":0.5693932175636292},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5447233319282532},{"id":"https://openalex.org/C134444547","wikidata":"https://www.wikidata.org/wiki/Q585230","display_name":"Boolean network","level":3,"score":0.5038136839866638},{"id":"https://openalex.org/C39743133","wikidata":"https://www.wikidata.org/wiki/Q3262595","display_name":"Signalling","level":2,"score":0.49548184871673584},{"id":"https://openalex.org/C87868495","wikidata":"https://www.wikidata.org/wiki/Q750843","display_name":"Information processing","level":2,"score":0.493717759847641},{"id":"https://openalex.org/C2983568541","wikidata":"https://www.wikidata.org/wiki/Q389772","display_name":"Information transmission","level":2,"score":0.48202431201934814},{"id":"https://openalex.org/C2779843651","wikidata":"https://www.wikidata.org/wiki/Q7390335","display_name":"SIGNAL (programming language)","level":2,"score":0.47084471583366394},{"id":"https://openalex.org/C199845137","wikidata":"https://www.wikidata.org/wiki/Q145490","display_name":"Network topology","level":2,"score":0.46056705713272095},{"id":"https://openalex.org/C104122410","wikidata":"https://www.wikidata.org/wiki/Q1416406","display_name":"Network model","level":2,"score":0.44938981533050537},{"id":"https://openalex.org/C104267543","wikidata":"https://www.wikidata.org/wiki/Q208163","display_name":"Signal processing","level":3,"score":0.44721508026123047},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.44528454542160034},{"id":"https://openalex.org/C761482","wikidata":"https://www.wikidata.org/wiki/Q118093","display_name":"Transmission (telecommunications)","level":2,"score":0.44278639554977417},{"id":"https://openalex.org/C123757187","wikidata":"https://www.wikidata.org/wiki/Q9195957","display_name":"Network dynamics","level":2,"score":0.4282868802547455},{"id":"https://openalex.org/C184720557","wikidata":"https://www.wikidata.org/wiki/Q7825049","display_name":"Topology (electrical circuits)","level":2,"score":0.37114953994750977},{"id":"https://openalex.org/C31258907","wikidata":"https://www.wikidata.org/wiki/Q1301371","display_name":"Computer network","level":1,"score":0.2924153208732605},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.21101295948028564},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.19715973734855652},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.1856755018234253},{"id":"https://openalex.org/C187455244","wikidata":"https://www.wikidata.org/wiki/Q942353","display_name":"Boolean function","level":2,"score":0.17399144172668457},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.1688486635684967},{"id":"https://openalex.org/C76155785","wikidata":"https://www.wikidata.org/wiki/Q418","display_name":"Telecommunications","level":1,"score":0.16496515274047852},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.1604195535182953},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.12952309846878052},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.08690515160560608},{"id":"https://openalex.org/C66938386","wikidata":"https://www.wikidata.org/wiki/Q633538","display_name":"Structural engineering","level":1,"score":0.0},{"id":"https://openalex.org/C554190296","wikidata":"https://www.wikidata.org/wiki/Q47528","display_name":"Radar","level":2,"score":0.0},{"id":"https://openalex.org/C118615104","wikidata":"https://www.wikidata.org/wiki/Q121416","display_name":"Discrete mathematics","level":1,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C114614502","wikidata":"https://www.wikidata.org/wiki/Q76592","display_name":"Combinatorics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D002450","descriptor_name":"Cell Communication","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002450","descriptor_name":"Cell Communication","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002450","descriptor_name":"Cell Communication","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false}],"locations_count":9,"locations":[{"id":"doi:10.1371/journal.pcbi.1002297","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1002297","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1002297&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Computational Biology","raw_type":"journal-article"},{"id":"pmid:22174668","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22174668","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS computational biology","raw_type":null},{"id":"pmh:oai:repositori.upf.edu:10230/23711","is_oa":true,"landing_page_url":"http://hdl.handle.net/10230/23711","pdf_url":null,"source":{"id":"https://openalex.org/S4306402615","display_name":"Repositori digital de la UPF (Universitat Pompeu Fabra)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I170486558","host_organization_name":"Universitat Pompeu Fabra","host_organization_lineage":["https://openalex.org/I170486558"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:recercat.cat:2072/184383","is_oa":true,"landing_page_url":"http://hdl.handle.net/2117/14333","pdf_url":null,"source":{"id":"https://openalex.org/S4306402147","display_name":"RECERCAT (Consorci de Serveis Universitaris de Catalunya)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210090028","host_organization_name":"Consorci de Serveis Universitaris de Catalunya","host_organization_lineage":["https://openalex.org/I4210090028"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"pmh:oai:upcommons.upc.edu:2117/14333","is_oa":true,"landing_page_url":"https://hdl.handle.net/2117/14333","pdf_url":null,"source":{"id":"https://openalex.org/S4210207057","display_name":"QRU Quaderns de Recerca en Urbanisme","issn_l":"2014-9689","issn":["2014-9689","2385-6777"],"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/P4310322448","host_organization_name":"Q71272178","host_organization_lineage":["https://openalex.org/P4310322448"],"host_organization_lineage_names":["Q71272178"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.287.7937","is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.287.7937","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/7c/4a/PLoS_Comput_Biol_2011_Dec_8_7(12)_e1002297.tar.gz","raw_type":"text"},{"id":"pmh:oai:doaj.org/article:5bed7499048a41ae969285beac4ccfea","is_oa":true,"landing_page_url":"https://doaj.org/article/5bed7499048a41ae969285beac4ccfea","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Computational Biology, Vol 7, Iss 12, p e1002297 (2011)","raw_type":"article"},{"id":"pmh:oai:europepmc.org:2244002","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3234210","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:figshare.com:article/130761","is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/Information_Routing_Driven_by_Background_Chatter_in_a_Signaling_Network/130761","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"}],"best_oa_location":{"id":"doi:10.1371/journal.pcbi.1002297","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1002297","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1002297&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Computational Biology","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G196208344","display_name":null,"funder_award_id":"2009SGR","funder_id":"https://openalex.org/F4320321505","funder_display_name":"Generalitat de Catalunya"},{"id":"https://openalex.org/G4449826398","display_name":null,"funder_award_id":"2009SGR116","funder_id":"https://openalex.org/F4320321505","funder_display_name":"Generalitat de Catalunya"}],"funders":[{"id":"https://openalex.org/F4320321505","display_name":"Generalitat de Catalunya","ror":"https://ror.org/01bg62x04"},{"id":"https://openalex.org/F4320322121","display_name":"Instituci\u00f3 Catalana de Recerca i Estudis Avan\u00e7ats","ror":"https://ror.org/0371hy230"},{"id":"https://openalex.org/F4320334923","display_name":"Instituto de Salud Carlos III","ror":"https://ror.org/00ca2c886"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1994877332.pdf","grobid_xml":"https://content.openalex.org/works/W1994877332.grobid-xml"},"referenced_works_count":44,"referenced_works":["https://openalex.org/W1541206712","https://openalex.org/W1690786280","https://openalex.org/W1909400967","https://openalex.org/W1976811090","https://openalex.org/W1979376088","https://openalex.org/W1981607001","https://openalex.org/W1982309495","https://openalex.org/W1991980854","https://openalex.org/W1998048927","https://openalex.org/W2015326650","https://openalex.org/W2029010014","https://openalex.org/W2030945597","https://openalex.org/W2040889971","https://openalex.org/W2044784465","https://openalex.org/W2052120747","https://openalex.org/W2052862499","https://openalex.org/W2057466720","https://openalex.org/W2061624209","https://openalex.org/W2063577759","https://openalex.org/W2065546165","https://openalex.org/W2068999270","https://openalex.org/W2080721009","https://openalex.org/W2090209293","https://openalex.org/W2092215419","https://openalex.org/W2092755129","https://openalex.org/W2093051682","https://openalex.org/W2095701698","https://openalex.org/W2100755177","https://openalex.org/W2110139532","https://openalex.org/W2114518254","https://openalex.org/W2121024688","https://openalex.org/W2132935366","https://openalex.org/W2136498480","https://openalex.org/W2136559804","https://openalex.org/W2139568168","https://openalex.org/W2142400903","https://openalex.org/W2145899141","https://openalex.org/W2152532651","https://openalex.org/W2153258203","https://openalex.org/W2157306201","https://openalex.org/W2157979510","https://openalex.org/W2157989234","https://openalex.org/W2160854837","https://openalex.org/W2161682775"],"related_works":["https://openalex.org/W2672115273","https://openalex.org/W1531018474","https://openalex.org/W2035036685","https://openalex.org/W2034774646","https://openalex.org/W2027350963","https://openalex.org/W3161588423","https://openalex.org/W4389115607","https://openalex.org/W2594483265","https://openalex.org/W3186603093","https://openalex.org/W2964149642"],"abstract_inverted_index":{"Living":[0],"systems":[1],"are":[2],"capable":[3],"of":[4,8,31,51,73,81,90,99,104,112,118,133,142],"processing":[5,83],"multiple":[6],"sources":[7],"information":[9,37,82,122,143],"simultaneously.":[10],"This":[11],"is":[12,34,38],"true":[13],"even":[14],"at":[15],"the":[16,25,29,49,67,71,74,79,87,100,110,116,119,130,134,140,149,161],"cellular":[17],"level,":[18],"where":[19],"not":[20],"only":[21],"coexisting":[22],"signals":[23,124],"stimulate":[24],"cell,":[26,93],"but":[27],"also":[28],"presence":[30],"fluctuating":[32],"conditions":[33],"significant.":[35],"When":[36],"received":[39],"by":[40,84],"a":[41,56,91,96,105,126],"cell":[42],"signaling":[43,88,162],"network":[44,68,89,103,135,163],"via":[45],"one":[46],"specific":[47],"input,":[48],"existence":[50],"other":[52],"stimuli":[53],"can":[54],"provide":[55],"background":[57],"activity":[58,131],"-or":[59],"chatter-":[60],"that":[61,109,148],"may":[62],"affect":[63],"signal":[64,101],"transmission":[65],"through":[66],"and,":[69],"therefore,":[70],"response":[72,117],"cell.":[75],"Here":[76],"we":[77],"study":[78],"modulation":[80],"chatter":[85,114],"in":[86,95,125],"human":[92],"specifically,":[94],"Boolean":[97],"model":[98],"transduction":[102],"fibroblast.":[106],"We":[107],"observe":[108],"level":[111],"external":[113],"shapes":[115],"system":[120],"to":[121,160],"carrying":[123],"nontrivial":[127],"manner,":[128],"modulates":[129],"levels":[132],"outputs,":[136],"and":[137,151,164],"effectively":[138],"determines":[139],"paths":[141],"flow.":[144],"Our":[145],"results":[146],"show":[147],"interactions":[150],"node":[152],"dynamics,":[153],"far":[154],"from":[155],"being":[156],"random,":[157],"confer":[158],"versatility":[159],"allow":[165],"transitions":[166],"between":[167],"different":[168],"information-processing":[169],"scenarios.":[170]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":2}],"updated_date":"2026-04-10T15:06:20.359241","created_date":"2025-10-10T00:00:00"}