{"id":"https://openalex.org/W2063311473","doi":"https://doi.org/10.1371/journal.pcbi.1001060","title":"Estimation of Parent Specific DNA Copy Number in Tumors using High-Density Genotyping Arrays","display_name":"Estimation of Parent Specific DNA Copy Number in Tumors using High-Density Genotyping Arrays","publication_year":2011,"publication_date":"2011-01-27","ids":{"openalex":"https://openalex.org/W2063311473","doi":"https://doi.org/10.1371/journal.pcbi.1001060","mag":"2063311473","pmid":"https://pubmed.ncbi.nlm.nih.gov/21298078"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pcbi.1001060","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1001060","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1001060&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Computational Biology","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1001060&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100353564","display_name":"Hao Chen","orcid":"https://orcid.org/0000-0002-5210-8924"},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hao Chen","raw_affiliation_strings":["Department of Statistics, Stanford University, Stanford, California, United States of America"],"affiliations":[{"raw_affiliation_string":"Department of Statistics, Stanford University, Stanford, California, United States of America","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090567392","display_name":"Haipeng Xing","orcid":"https://orcid.org/0000-0003-2048-2353"},"institutions":[{"id":"https://openalex.org/I59553526","display_name":"Stony Brook University","ror":"https://ror.org/05qghxh33","country_code":"US","type":"education","lineage":["https://openalex.org/I59553526"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Haipeng Xing","raw_affiliation_strings":["Department of Applied Mathematics and Statistics, SUNY at Stony Brook, Stony Brook, New York, United States of America"],"affiliations":[{"raw_affiliation_string":"Department of Applied Mathematics and Statistics, SUNY at Stony Brook, Stony Brook, New York, United States of America","institution_ids":["https://openalex.org/I59553526"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5022335574","display_name":"Nancy R. Zhang","orcid":"https://orcid.org/0000-0002-0880-5749"},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Nancy R. Zhang","raw_affiliation_strings":["Department of Statistics, Stanford University, Stanford, California, United States of America"],"affiliations":[{"raw_affiliation_string":"Department of Statistics, Stanford University, Stanford, California, United States of America","institution_ids":["https://openalex.org/I97018004"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5022335574"],"corresponding_institution_ids":["https://openalex.org/I97018004"],"apc_list":{"value":2655,"currency":"USD","value_usd":2655},"apc_paid":{"value":2655,"currency":"USD","value_usd":2655},"fwci":5.4069,"has_fulltext":true,"cited_by_count":44,"citation_normalized_percentile":{"value":0.96023384,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"7","issue":"1","first_page":"e1001060","last_page":"e1001060"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11213","display_name":"Genomic variations and chromosomal abnormalities","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11213","display_name":"Genomic variations and chromosomal abnormalities","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.9972000122070312,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/copy-number-analysis","display_name":"Copy number analysis","score":0.8493411540985107},{"id":"https://openalex.org/keywords/copy-number-variation","display_name":"Copy-number variation","score":0.8109283447265625},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.6869470477104187},{"id":"https://openalex.org/keywords/genotyping","display_name":"Genotyping","score":0.6631525158882141},{"id":"https://openalex.org/keywords/loss-of-heterozygosity","display_name":"Loss of heterozygosity","score":0.629790186882019},{"id":"https://openalex.org/keywords/comparative-genomic-hybridization","display_name":"Comparative genomic hybridization","score":0.6259903907775879},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.6112804412841797},{"id":"https://openalex.org/keywords/gene-dosage","display_name":"Gene dosage","score":0.5332189798355103},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5263335108757019},{"id":"https://openalex.org/keywords/breakpoint","display_name":"Breakpoint","score":0.45863354206085205},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.440766841173172},{"id":"https://openalex.org/keywords/low-copy-number","display_name":"Low copy number","score":0.42320147156715393},{"id":"https://openalex.org/keywords/dna-microarray","display_name":"DNA microarray","score":0.4158502221107483},{"id":"https://openalex.org/keywords/genotype","display_name":"Genotype","score":0.3247561454772949},{"id":"https://openalex.org/keywords/allele","display_name":"Allele","score":0.2903285026550293},{"id":"https://openalex.org/keywords/chromosome","display_name":"Chromosome","score":0.23596853017807007},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.21302828192710876}],"concepts":[{"id":"https://openalex.org/C166608930","wikidata":"https://www.wikidata.org/wiki/Q5169175","display_name":"Copy number analysis","level":5,"score":0.8493411540985107},{"id":"https://openalex.org/C120821319","wikidata":"https://www.wikidata.org/wiki/Q1501491","display_name":"Copy-number variation","level":4,"score":0.8109283447265625},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6869470477104187},{"id":"https://openalex.org/C31467283","wikidata":"https://www.wikidata.org/wiki/Q912147","display_name":"Genotyping","level":4,"score":0.6631525158882141},{"id":"https://openalex.org/C143589142","wikidata":"https://www.wikidata.org/wiki/Q2617554","display_name":"Loss of heterozygosity","level":4,"score":0.629790186882019},{"id":"https://openalex.org/C124942203","wikidata":"https://www.wikidata.org/wiki/Q656638","display_name":"Comparative genomic hybridization","level":4,"score":0.6259903907775879},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.6112804412841797},{"id":"https://openalex.org/C55548728","wikidata":"https://www.wikidata.org/wiki/Q1465102","display_name":"Gene dosage","level":4,"score":0.5332189798355103},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5263335108757019},{"id":"https://openalex.org/C206936463","wikidata":"https://www.wikidata.org/wiki/Q634179","display_name":"Breakpoint","level":4,"score":0.45863354206085205},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.440766841173172},{"id":"https://openalex.org/C2777116013","wikidata":"https://www.wikidata.org/wiki/Q6692995","display_name":"Low copy number","level":4,"score":0.42320147156715393},{"id":"https://openalex.org/C95371953","wikidata":"https://www.wikidata.org/wiki/Q591745","display_name":"DNA microarray","level":4,"score":0.4158502221107483},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.3247561454772949},{"id":"https://openalex.org/C180754005","wikidata":"https://www.wikidata.org/wiki/Q80726","display_name":"Allele","level":3,"score":0.2903285026550293},{"id":"https://openalex.org/C30481170","wikidata":"https://www.wikidata.org/wiki/Q37748","display_name":"Chromosome","level":3,"score":0.23596853017807007},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.21302828192710876},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000483","descriptor_name":"Alleles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000483","descriptor_name":"Alleles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000483","descriptor_name":"Alleles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004273","descriptor_name":"DNA, Neoplasm","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004273","descriptor_name":"DNA, Neoplasm","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004273","descriptor_name":"DNA, Neoplasm","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005838","descriptor_name":"Genotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005838","descriptor_name":"Genotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005838","descriptor_name":"Genotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008390","descriptor_name":"Markov Chains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008390","descriptor_name":"Markov Chains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008390","descriptor_name":"Markov Chains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010290","descriptor_name":"Parents","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010290","descriptor_name":"Parents","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010290","descriptor_name":"Parents","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018628","descriptor_name":"Gene Dosage","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018628","descriptor_name":"Gene Dosage","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018628","descriptor_name":"Gene Dosage","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020641","descriptor_name":"Polymorphism, Single Nucleotide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020641","descriptor_name":"Polymorphism, Single Nucleotide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020641","descriptor_name":"Polymorphism, Single Nucleotide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":9,"locations":[{"id":"doi:10.1371/journal.pcbi.1001060","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1001060","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1001060&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Computational Biology","raw_type":"journal-article"},{"id":"pmid:21298078","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21298078","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS computational biology","raw_type":null},{"id":"pmh:oai:repository.upenn.edu:statistics_papers-1175","is_oa":false,"landing_page_url":"https://repository.upenn.edu/cgi/viewcontent.cgi?article=1175&context=statistics_papers","pdf_url":null,"source":{"id":"https://openalex.org/S4306402083","display_name":"ScholarlyCommons (University of Pennsylvania)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I79576946","host_organization_name":"University of Pennsylvania","host_organization_lineage":["https://openalex.org/I79576946"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Statistics Papers","raw_type":"text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.606.8321","is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.606.8321","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://statweb.stanford.edu/~nzhang/ParentSpecificCopyNumber.pdf","raw_type":"text"},{"id":"pmh:oai:RePEc:plo:pcbi00:1001060","is_oa":false,"landing_page_url":"https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1001060","pdf_url":null,"source":{"id":"https://openalex.org/S4306401271","display_name":"RePEc: Research Papers in Economics","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I77793887","host_organization_name":"Federal Reserve Bank of St. Louis","host_organization_lineage":["https://openalex.org/I77793887"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"},{"id":"pmh:oai:doaj.org/article:797161bcb4e14e2c96a1d82c066c6433","is_oa":true,"landing_page_url":"https://doaj.org/article/797161bcb4e14e2c96a1d82c066c6433","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Computational Biology, Vol 7, Iss 1, p e1001060 (2011)","raw_type":"article"},{"id":"pmh:oai:figshare.com:article/139221","is_oa":true,"landing_page_url":"https://figshare.com/articles/Estimation_of_Parent_Specific_DNA_Copy_Number_in_Tumors_using_High_Density_Genotyping_Arrays/139221","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"},{"id":"pmh:oai:pubmedcentral.nih.gov:3029233","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3029233","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Comput Biol","raw_type":"Text"},{"id":"pmh:oai:repository.upenn.edu:20.500.14332/47810","is_oa":false,"landing_page_url":"https://repository.upenn.edu/handle/20.500.14332/47810","pdf_url":null,"source":{"id":"https://openalex.org/S4306402083","display_name":"ScholarlyCommons (University of Pennsylvania)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I79576946","host_organization_name":"University of Pennsylvania","host_organization_lineage":["https://openalex.org/I79576946"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"7","raw_type":"Article"}],"best_oa_location":{"id":"doi:10.1371/journal.pcbi.1001060","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1001060","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1001060&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Computational Biology","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G6738113153","display_name":"New Change-point Problems in Genomic Profiling","funder_award_id":"0906394","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G7860317347","display_name":null,"funder_award_id":"R37EB02784","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G848032724","display_name":null,"funder_award_id":"Science","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2063311473.pdf","grobid_xml":"https://content.openalex.org/works/W2063311473.grobid-xml"},"referenced_works_count":42,"referenced_works":["https://openalex.org/W1481143593","https://openalex.org/W1484187172","https://openalex.org/W1559899545","https://openalex.org/W1771933790","https://openalex.org/W1988785484","https://openalex.org/W1994381110","https://openalex.org/W2016299037","https://openalex.org/W2017535462","https://openalex.org/W2025183726","https://openalex.org/W2033041275","https://openalex.org/W2034269086","https://openalex.org/W2038437697","https://openalex.org/W2056121212","https://openalex.org/W2058769734","https://openalex.org/W2066721762","https://openalex.org/W2071221560","https://openalex.org/W2080920780","https://openalex.org/W2099441054","https://openalex.org/W2100725331","https://openalex.org/W2104241530","https://openalex.org/W2114553186","https://openalex.org/W2121308112","https://openalex.org/W2122410503","https://openalex.org/W2123452832","https://openalex.org/W2127710810","https://openalex.org/W2133174470","https://openalex.org/W2134095688","https://openalex.org/W2134672574","https://openalex.org/W2137518296","https://openalex.org/W2142452151","https://openalex.org/W2143362349","https://openalex.org/W2145954121","https://openalex.org/W2146948473","https://openalex.org/W2147696849","https://openalex.org/W2149681218","https://openalex.org/W2154432179","https://openalex.org/W2156643308","https://openalex.org/W2169043705","https://openalex.org/W2169986510","https://openalex.org/W2241687416","https://openalex.org/W2341348895","https://openalex.org/W6690421004"],"related_works":["https://openalex.org/W2089464420","https://openalex.org/W2050860556","https://openalex.org/W3032170682","https://openalex.org/W2130793549","https://openalex.org/W4231651198","https://openalex.org/W2092343534","https://openalex.org/W2342878392","https://openalex.org/W2030684132","https://openalex.org/W2586505243","https://openalex.org/W2030481069"],"abstract_inverted_index":{"Chromosomal":[0],"gains":[1,194],"and":[2,13,62,69,94,103,125,195,205],"losses":[3],"comprise":[4],"an":[5,96,183],"important":[6,57],"type":[7],"of":[8,42,77,160,192,199,203,208,210,213],"genetic":[9],"change":[10],"in":[11,91,165],"tumors,":[12],"can":[14,104,126,179],"now":[15],"be":[16,105,180],"assayed":[17],"using":[18],"microarray":[19],"hybridization-based":[20],"experiments.":[21],"Most":[22],"current":[23,111],"statistical":[24],"models":[25],"for":[26,58,64,70,86],"DNA":[27,88],"copy":[28,32,54,89,136,162,185,200],"number":[29,90,163,186],"estimate":[30,127],"total":[31],"number,":[33,55],"which":[34],"do":[35],"not":[36,120],"distinguish":[37],"between":[38],"the":[39,43,78,110,128,133,149,161,175,190,197,206],"underlying":[40],"quantities":[41],"two":[44],"inherited":[45,215],"chromosomes.":[46,216],"This":[47],"latter":[48],"information,":[49],"sometimes":[50],"called":[51],"parent":[52,134],"specific":[53,135],"is":[56,100,141],"identifying":[59],"allele-specific":[60,184],"amplifications":[61],"deletions,":[63],"quantifying":[65],"normal":[66,123],"cell":[67],"contamination,":[68],"giving":[71,155],"a":[72,82,156],"more":[73,157],"complete":[74],"molecular":[75],"portrait":[76],"tumor.":[79],"We":[80],"propose":[81],"stochastic":[83],"segmentation":[84],"model":[85],"parent-specific":[87],"tumor":[92],"samples,":[93,124],"give":[95],"estimation":[97],"procedure":[98],"that":[99,178],"computationally":[101],"efficient":[102],"applied":[106],"to":[107,143],"data":[108],"from":[109,148,182],"high":[112],"density":[113],"genotyping":[114],"platforms.":[115],"The":[116,138],"proposed":[117],"method":[118,140],"does":[119],"require":[121],"matched":[122],"unknown":[129],"genotypes":[130],"simultaneously":[131],"with":[132],"number.":[137],"new":[139],"used":[142],"analyze":[144],"223":[145],"glioblastoma":[146],"samples":[147,173],"Cancer":[150],"Genome":[151],"Atlas":[152],"(TCGA)":[153],"project,":[154],"comprehensive":[158],"summary":[159],"events":[164],"these":[166,172],"samples.":[167],"Detailed":[168],"case":[169],"studies":[170],"on":[171],"reveal":[174],"additional":[176],"insights":[177],"gained":[181],"analysis,":[187],"such":[188],"as":[189],"quantification":[191],"fractional":[193],"losses,":[196],"identification":[198],"neutral":[201],"loss":[202],"heterozygosity,":[204],"characterization":[207],"regions":[209],"simultaneous":[211],"changes":[212],"both":[214]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":6},{"year":2014,"cited_by_count":10},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":9}],"updated_date":"2026-04-13T07:58:08.660418","created_date":"2025-10-10T00:00:00"}