{"id":"https://openalex.org/W2066783383","doi":"https://doi.org/10.1371/journal.pcbi.1000248","title":"Tag-Trigger-Consolidation: A Model of Early and Late Long-Term-Potentiation and Depression","display_name":"Tag-Trigger-Consolidation: A Model of Early and Late Long-Term-Potentiation and Depression","publication_year":2008,"publication_date":"2008-12-26","ids":{"openalex":"https://openalex.org/W2066783383","doi":"https://doi.org/10.1371/journal.pcbi.1000248","mag":"2066783383","pmid":"https://pubmed.ncbi.nlm.nih.gov/19112486"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pcbi.1000248","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1000248","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1000248&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Computational Biology","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1000248&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5039497694","display_name":"Claudia Clopath","orcid":"https://orcid.org/0000-0003-4507-8648"},"institutions":[{"id":"https://openalex.org/I5124864","display_name":"\u00c9cole Polytechnique F\u00e9d\u00e9rale de Lausanne","ror":"https://ror.org/02s376052","country_code":"CH","type":"education","lineage":["https://openalex.org/I2799323385","https://openalex.org/I5124864"]},{"id":"https://openalex.org/I4210145373","display_name":"Federal Supreme Court of Switzerland","ror":"https://ror.org/0494r5h25","country_code":"CH","type":"government","lineage":["https://openalex.org/I4210145373"]},{"id":"https://openalex.org/I142476485","display_name":"\u00c9cole Polytechnique","ror":"https://ror.org/05hy3tk52","country_code":"FR","type":"education","lineage":["https://openalex.org/I142476485","https://openalex.org/I4210145102"]}],"countries":["CH","FR"],"is_corresponding":false,"raw_author_name":"Claudia Clopath","raw_affiliation_strings":["Laboratory of Computational Neuroscience, Brain-Mind Institute and School of Computer and Communication Sciences, Ecole Polytechnique F\u00e9d\u00e9rale de Lausanne, Lausanne, Switzerland","Laboratory of Computational Neuroscience, Brain-Mind Institute and School","F\u00e9d\u00e9rale de Lausanne, Lausanne, Switzerland","of Computer and Communication Sciences, Ecole Polytechnique"],"affiliations":[{"raw_affiliation_string":"Laboratory of Computational Neuroscience, Brain-Mind Institute and School of Computer and Communication Sciences, Ecole Polytechnique F\u00e9d\u00e9rale de Lausanne, Lausanne, Switzerland","institution_ids":["https://openalex.org/I5124864"]},{"raw_affiliation_string":"Laboratory of Computational Neuroscience, Brain-Mind Institute and School","institution_ids":[]},{"raw_affiliation_string":"F\u00e9d\u00e9rale de Lausanne, Lausanne, Switzerland","institution_ids":["https://openalex.org/I4210145373"]},{"raw_affiliation_string":"of Computer and Communication Sciences, Ecole Polytechnique","institution_ids":["https://openalex.org/I142476485"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034125654","display_name":"Lorric Ziegler","orcid":"https://orcid.org/0000-0002-6485-3956"},"institutions":[{"id":"https://openalex.org/I142476485","display_name":"\u00c9cole Polytechnique","ror":"https://ror.org/05hy3tk52","country_code":"FR","type":"education","lineage":["https://openalex.org/I142476485","https://openalex.org/I4210145102"]},{"id":"https://openalex.org/I4210145373","display_name":"Federal Supreme Court of Switzerland","ror":"https://ror.org/0494r5h25","country_code":"CH","type":"government","lineage":["https://openalex.org/I4210145373"]}],"countries":["CH","FR"],"is_corresponding":false,"raw_author_name":"Lorric Ziegler","raw_affiliation_strings":["F\u00e9d\u00e9rale de Lausanne, Lausanne, Switzerland","Laboratory of Computational Neuroscience, Brain-Mind Institute and School","of Computer and Communication Sciences, Ecole Polytechnique"],"affiliations":[{"raw_affiliation_string":"F\u00e9d\u00e9rale de Lausanne, Lausanne, Switzerland","institution_ids":["https://openalex.org/I4210145373"]},{"raw_affiliation_string":"Laboratory of Computational Neuroscience, Brain-Mind Institute and School","institution_ids":[]},{"raw_affiliation_string":"of Computer and Communication Sciences, Ecole Polytechnique","institution_ids":["https://openalex.org/I142476485"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030069824","display_name":"Eleni Vasilaki","orcid":"https://orcid.org/0000-0003-3705-7070"},"institutions":[{"id":"https://openalex.org/I4210145373","display_name":"Federal Supreme Court of Switzerland","ror":"https://ror.org/0494r5h25","country_code":"CH","type":"government","lineage":["https://openalex.org/I4210145373"]},{"id":"https://openalex.org/I142476485","display_name":"\u00c9cole Polytechnique","ror":"https://ror.org/05hy3tk52","country_code":"FR","type":"education","lineage":["https://openalex.org/I142476485","https://openalex.org/I4210145102"]}],"countries":["CH","FR"],"is_corresponding":false,"raw_author_name":"Eleni Vasilaki","raw_affiliation_strings":["F\u00e9d\u00e9rale de Lausanne, Lausanne, Switzerland","Laboratory of Computational Neuroscience, Brain-Mind Institute and School","of Computer and Communication Sciences, Ecole Polytechnique"],"affiliations":[{"raw_affiliation_string":"F\u00e9d\u00e9rale de Lausanne, Lausanne, Switzerland","institution_ids":["https://openalex.org/I4210145373"]},{"raw_affiliation_string":"Laboratory of Computational Neuroscience, Brain-Mind Institute and School","institution_ids":[]},{"raw_affiliation_string":"of Computer and Communication Sciences, Ecole Polytechnique","institution_ids":["https://openalex.org/I142476485"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056989928","display_name":"Lars B\u00fcsing","orcid":null},"institutions":[{"id":"https://openalex.org/I142476485","display_name":"\u00c9cole Polytechnique","ror":"https://ror.org/05hy3tk52","country_code":"FR","type":"education","lineage":["https://openalex.org/I142476485","https://openalex.org/I4210145102"]},{"id":"https://openalex.org/I4210145373","display_name":"Federal Supreme Court of Switzerland","ror":"https://ror.org/0494r5h25","country_code":"CH","type":"government","lineage":["https://openalex.org/I4210145373"]}],"countries":["CH","FR"],"is_corresponding":false,"raw_author_name":"Lars B\u00fcsing","raw_affiliation_strings":["F\u00e9d\u00e9rale de Lausanne, Lausanne, Switzerland","Laboratory of Computational Neuroscience, Brain-Mind Institute and School","of Computer and Communication Sciences, Ecole Polytechnique"],"affiliations":[{"raw_affiliation_string":"F\u00e9d\u00e9rale de Lausanne, Lausanne, Switzerland","institution_ids":["https://openalex.org/I4210145373"]},{"raw_affiliation_string":"Laboratory of Computational Neuroscience, Brain-Mind Institute and School","institution_ids":[]},{"raw_affiliation_string":"of Computer and Communication Sciences, Ecole Polytechnique","institution_ids":["https://openalex.org/I142476485"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5003480477","display_name":"Wulfram Gerstner","orcid":"https://orcid.org/0000-0002-4344-2189"},"institutions":[{"id":"https://openalex.org/I142476485","display_name":"\u00c9cole Polytechnique","ror":"https://ror.org/05hy3tk52","country_code":"FR","type":"education","lineage":["https://openalex.org/I142476485","https://openalex.org/I4210145102"]},{"id":"https://openalex.org/I4210145373","display_name":"Federal Supreme Court of Switzerland","ror":"https://ror.org/0494r5h25","country_code":"CH","type":"government","lineage":["https://openalex.org/I4210145373"]}],"countries":["CH","FR"],"is_corresponding":true,"raw_author_name":"Wulfram Gerstner","raw_affiliation_strings":["F\u00e9d\u00e9rale de Lausanne, Lausanne, Switzerland","Laboratory of Computational Neuroscience, Brain-Mind Institute and School","of Computer and Communication Sciences, Ecole Polytechnique"],"affiliations":[{"raw_affiliation_string":"F\u00e9d\u00e9rale de Lausanne, Lausanne, Switzerland","institution_ids":["https://openalex.org/I4210145373"]},{"raw_affiliation_string":"Laboratory of Computational Neuroscience, Brain-Mind Institute and School","institution_ids":[]},{"raw_affiliation_string":"of Computer and Communication Sciences, Ecole Polytechnique","institution_ids":["https://openalex.org/I142476485"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5003480477"],"corresponding_institution_ids":["https://openalex.org/I142476485","https://openalex.org/I4210145373"],"apc_list":{"value":2655,"currency":"USD","value_usd":2655},"apc_paid":{"value":2655,"currency":"USD","value_usd":2655},"fwci":2.651,"has_fulltext":true,"cited_by_count":158,"citation_normalized_percentile":{"value":0.89955478,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":96,"max":100},"biblio":{"volume":"4","issue":"12","first_page":"e1000248","last_page":"e1000248"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10502","display_name":"Advanced Memory and Neural Computing","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/long-term-potentiation","display_name":"Long-term potentiation","score":0.8439218997955322},{"id":"https://openalex.org/keywords/synaptic-plasticity","display_name":"Synaptic plasticity","score":0.8115231990814209},{"id":"https://openalex.org/keywords/metaplasticity","display_name":"Metaplasticity","score":0.7323129773139954},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.7192518711090088},{"id":"https://openalex.org/keywords/synaptic-augmentation","display_name":"Synaptic augmentation","score":0.6417331099510193},{"id":"https://openalex.org/keywords/synaptic-fatigue","display_name":"Synaptic fatigue","score":0.6259140968322754},{"id":"https://openalex.org/keywords/ltp-induction","display_name":"LTP induction","score":0.6058197617530823},{"id":"https://openalex.org/keywords/nonsynaptic-plasticity","display_name":"Nonsynaptic plasticity","score":0.5691743493080139},{"id":"https://openalex.org/keywords/neuronal-memory-allocation","display_name":"Neuronal memory allocation","score":0.5329443216323853},{"id":"https://openalex.org/keywords/memory-consolidation","display_name":"Memory consolidation","score":0.5268707871437073},{"id":"https://openalex.org/keywords/synaptic-scaling","display_name":"Synaptic scaling","score":0.5172877311706543},{"id":"https://openalex.org/keywords/postsynaptic-potential","display_name":"Postsynaptic potential","score":0.4864825904369354},{"id":"https://openalex.org/keywords/homosynaptic-plasticity","display_name":"Homosynaptic plasticity","score":0.4635782241821289},{"id":"https://openalex.org/keywords/excitatory-postsynaptic-potential","display_name":"Excitatory postsynaptic potential","score":0.42981404066085815},{"id":"https://openalex.org/keywords/post-tetanic-potentiation","display_name":"Post-tetanic potentiation","score":0.4248567819595337},{"id":"https://openalex.org/keywords/neural-facilitation","display_name":"Neural facilitation","score":0.4175878167152405},{"id":"https://openalex.org/keywords/inhibitory-postsynaptic-potential","display_name":"Inhibitory postsynaptic potential","score":0.3824794888496399},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.3535759747028351},{"id":"https://openalex.org/keywords/hippocampus","display_name":"Hippocampus","score":0.11306893825531006},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.059509724378585815},{"id":"https://openalex.org/keywords/receptor","display_name":"Receptor","score":0.04674583673477173}],"concepts":[{"id":"https://openalex.org/C25274449","wikidata":"https://www.wikidata.org/wiki/Q1805481","display_name":"Long-term potentiation","level":3,"score":0.8439218997955322},{"id":"https://openalex.org/C98229152","wikidata":"https://www.wikidata.org/wiki/Q1551556","display_name":"Synaptic plasticity","level":3,"score":0.8115231990814209},{"id":"https://openalex.org/C194973443","wikidata":"https://www.wikidata.org/wiki/Q1420291","display_name":"Metaplasticity","level":4,"score":0.7323129773139954},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.7192518711090088},{"id":"https://openalex.org/C95293801","wikidata":"https://www.wikidata.org/wiki/Q7662035","display_name":"Synaptic augmentation","level":4,"score":0.6417331099510193},{"id":"https://openalex.org/C125667969","wikidata":"https://www.wikidata.org/wiki/Q7662036","display_name":"Synaptic fatigue","level":4,"score":0.6259140968322754},{"id":"https://openalex.org/C2776328245","wikidata":"https://www.wikidata.org/wiki/Q6460191","display_name":"LTP induction","level":4,"score":0.6058197617530823},{"id":"https://openalex.org/C26410512","wikidata":"https://www.wikidata.org/wiki/Q3906363","display_name":"Nonsynaptic plasticity","level":5,"score":0.5691743493080139},{"id":"https://openalex.org/C150720761","wikidata":"https://www.wikidata.org/wiki/Q7002465","display_name":"Neuronal memory allocation","level":5,"score":0.5329443216323853},{"id":"https://openalex.org/C48455012","wikidata":"https://www.wikidata.org/wiki/Q2892593","display_name":"Memory consolidation","level":3,"score":0.5268707871437073},{"id":"https://openalex.org/C117718741","wikidata":"https://www.wikidata.org/wiki/Q7662041","display_name":"Synaptic scaling","level":5,"score":0.5172877311706543},{"id":"https://openalex.org/C197341189","wikidata":"https://www.wikidata.org/wiki/Q863533","display_name":"Postsynaptic potential","level":3,"score":0.4864825904369354},{"id":"https://openalex.org/C83119035","wikidata":"https://www.wikidata.org/wiki/Q17030659","display_name":"Homosynaptic plasticity","level":5,"score":0.4635782241821289},{"id":"https://openalex.org/C112592302","wikidata":"https://www.wikidata.org/wiki/Q1207387","display_name":"Excitatory postsynaptic potential","level":3,"score":0.42981404066085815},{"id":"https://openalex.org/C118232355","wikidata":"https://www.wikidata.org/wiki/Q7233588","display_name":"Post-tetanic potentiation","level":4,"score":0.4248567819595337},{"id":"https://openalex.org/C29561615","wikidata":"https://www.wikidata.org/wiki/Q14565715","display_name":"Neural facilitation","level":4,"score":0.4175878167152405},{"id":"https://openalex.org/C17077164","wikidata":"https://www.wikidata.org/wiki/Q1185869","display_name":"Inhibitory postsynaptic potential","level":2,"score":0.3824794888496399},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3535759747028351},{"id":"https://openalex.org/C2781161787","wikidata":"https://www.wikidata.org/wiki/Q48360","display_name":"Hippocampus","level":2,"score":0.11306893825531006},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.059509724378585815},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.04674583673477173}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008959","descriptor_name":"Models, Neurological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008959","descriptor_name":"Models, Neurological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008959","descriptor_name":"Models, Neurological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009415","descriptor_name":"Nerve Net","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009415","descriptor_name":"Nerve Net","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009415","descriptor_name":"Nerve Net","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009435","descriptor_name":"Synaptic Transmission","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009435","descriptor_name":"Synaptic Transmission","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009435","descriptor_name":"Synaptic Transmission","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009473","descriptor_name":"Neuronal Plasticity","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009473","descriptor_name":"Neuronal Plasticity","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009473","descriptor_name":"Neuronal Plasticity","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D017774","descriptor_name":"Long-Term Potentiation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D017774","descriptor_name":"Long-Term Potentiation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D017774","descriptor_name":"Long-Term Potentiation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D036881","descriptor_name":"Long-Term Synaptic Depression","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D036881","descriptor_name":"Long-Term Synaptic Depression","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D036881","descriptor_name":"Long-Term Synaptic Depression","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false}],"locations_count":7,"locations":[{"id":"doi:10.1371/journal.pcbi.1000248","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1000248","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1000248&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Computational Biology","raw_type":"journal-article"},{"id":"pmid:19112486","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19112486","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS computational biology","raw_type":null},{"id":"pmh:oai:eprints.whiterose.ac.uk:99462","is_oa":false,"landing_page_url":null,"pdf_url":null,"source":{"id":"https://openalex.org/S4306400854","display_name":"White Rose Research Online (University of Leeds, The University of Sheffield, University of York)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I2800616092","host_organization_name":"White Rose University Consortium","host_organization_lineage":["https://openalex.org/I2800616092"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Article"},{"id":"pmh:oai:doaj.org/article:7a9cf5ca6fb245e4bd666bf8e73d5d21","is_oa":true,"landing_page_url":"https://doaj.org/article/7a9cf5ca6fb245e4bd666bf8e73d5d21","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Computational Biology, Vol 4, Iss 12, p e1000248 (2008)","raw_type":"article"},{"id":"pmh:oai:infoscience.epfl.ch:140442","is_oa":true,"landing_page_url":"http://infoscience.epfl.ch/record/140442","pdf_url":null,"source":{"id":"https://openalex.org/S4306400487","display_name":"Infoscience (Ecole Polytechnique F\u00e9d\u00e9rale de Lausanne)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:infoscience.tind.io:140442","is_oa":true,"landing_page_url":"https://infoscience.epfl.ch/handle/20.500.14299/41991","pdf_url":null,"source":{"id":"https://openalex.org/S4306400487","display_name":"Infoscience (Ecole Polytechnique F\u00e9d\u00e9rale de Lausanne)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"research article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2596310","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2596310","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Comput Biol","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1371/journal.pcbi.1000248","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1000248","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1000248&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Computational Biology","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G848032724","display_name":null,"funder_award_id":"Science","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320320924","display_name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung","ror":"https://ror.org/00yjd3n13"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2066783383.pdf","grobid_xml":"https://content.openalex.org/works/W2066783383.grobid-xml"},"referenced_works_count":69,"referenced_works":["https://openalex.org/W1486852018","https://openalex.org/W1542782021","https://openalex.org/W1670642870","https://openalex.org/W1733248925","https://openalex.org/W1802372728","https://openalex.org/W1969507049","https://openalex.org/W1969679257","https://openalex.org/W1975412204","https://openalex.org/W1978730538","https://openalex.org/W1985534367","https://openalex.org/W1986246844","https://openalex.org/W1995001752","https://openalex.org/W1996396557","https://openalex.org/W1999576398","https://openalex.org/W2000894573","https://openalex.org/W2009782005","https://openalex.org/W2011567013","https://openalex.org/W2011882079","https://openalex.org/W2012417073","https://openalex.org/W2021235911","https://openalex.org/W2021485981","https://openalex.org/W2024152195","https://openalex.org/W2033771479","https://openalex.org/W2041251386","https://openalex.org/W2049511526","https://openalex.org/W2050066016","https://openalex.org/W2051716212","https://openalex.org/W2055391909","https://openalex.org/W2056179104","https://openalex.org/W2060200435","https://openalex.org/W2060941075","https://openalex.org/W2061405268","https://openalex.org/W2069354675","https://openalex.org/W2069469260","https://openalex.org/W2077758457","https://openalex.org/W2082660315","https://openalex.org/W2083910902","https://openalex.org/W2090313382","https://openalex.org/W2092001091","https://openalex.org/W2095154996","https://openalex.org/W2096473662","https://openalex.org/W2096551329","https://openalex.org/W2101222204","https://openalex.org/W2101793659","https://openalex.org/W2107524792","https://openalex.org/W2116577160","https://openalex.org/W2117726420","https://openalex.org/W2123820663","https://openalex.org/W2124812605","https://openalex.org/W2128084896","https://openalex.org/W2128949090","https://openalex.org/W2129386380","https://openalex.org/W2138214290","https://openalex.org/W2152477898","https://openalex.org/W2153564253","https://openalex.org/W2155108447","https://openalex.org/W2158935809","https://openalex.org/W2162019295","https://openalex.org/W2162642602","https://openalex.org/W2185212694","https://openalex.org/W2282055800","https://openalex.org/W2312609093","https://openalex.org/W2911283634","https://openalex.org/W2914656440","https://openalex.org/W4214891130","https://openalex.org/W4238614602","https://openalex.org/W4242770316","https://openalex.org/W4250621041","https://openalex.org/W6689723076"],"related_works":["https://openalex.org/W24248087","https://openalex.org/W1153554031","https://openalex.org/W2112927743","https://openalex.org/W4287025849","https://openalex.org/W3188778237","https://openalex.org/W2909903989","https://openalex.org/W2481575045","https://openalex.org/W2064639670","https://openalex.org/W2007490344","https://openalex.org/W2004281064"],"abstract_inverted_index":{"Changes":[0],"in":[1,8],"synaptic":[2,18,36,41,55,62,75,87],"efficacies":[3],"need":[4],"to":[5,10,54,128],"be":[6],"long-lasting":[7],"order":[9],"serve":[11],"as":[12],"a":[13,43,50,66,80],"substrate":[14],"for":[15,46,104],"memory.":[16],"Experimentally,":[17],"plasticity":[19],"exhibits":[20],"phases":[21,73,95],"covering":[22],"the":[23,32,38,58,93,101,105,124,161],"induction":[24,111],"of":[25,35,40,61,74,83,96,107,120,141,146,155],"long-term":[26],"potentiation":[27],"and":[28,49,89,92,98,109,114],"depression":[29],"(LTP/LTD)":[30],"during":[31,57,123],"early":[33,127],"phase":[34,60],"plasticity,":[37],"setting":[39],"tags,":[42],"trigger":[44],"process":[45,149],"protein":[47,133],"synthesis,":[48],"slow":[51],"transition":[52,125],"leading":[53],"consolidation":[56],"late":[59,94,129],"plasticity.":[63,76],"We":[64],"present":[65],"mathematical":[67],"model":[68,78,102],"that":[69,136,151],"describes":[70],"these":[71],"different":[72],"The":[77,118,143],"explains":[79],"large":[81],"body":[82],"experimental":[84],"data":[85],"on":[86,112],"tagging":[88],"capture,":[90],"cross-tagging,":[91],"LTP":[97,108,130],"LTD.":[99],"Moreover,":[100],"accounts":[103],"dependence":[106],"LTD":[110],"voltage":[113],"presynaptic":[115],"stimulation":[116],"frequency.":[117],"stabilization":[119],"potentiated":[121],"synapses":[122,159],"from":[126],"occurs":[131],"by":[132,139,172],"synthesis":[134],"dynamics":[135],"are":[137,165],"shared":[138,148],"groups":[140],"synapses.":[142,177],"functional":[144],"consequence":[145],"this":[147],"is":[150],"previously":[152],"stabilized":[153],"patterns":[154],"strong":[156],"or":[157],"weak":[158],"onto":[160],"same":[162],"postsynaptic":[163],"neuron":[164],"well":[166],"protected":[167],"against":[168],"later":[169],"changes":[170],"induced":[171],"LTP/LTD":[173],"protocols":[174],"at":[175],"individual":[176]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":12},{"year":2024,"cited_by_count":16},{"year":2023,"cited_by_count":9},{"year":2022,"cited_by_count":10},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":7},{"year":2019,"cited_by_count":7},{"year":2018,"cited_by_count":8},{"year":2017,"cited_by_count":13},{"year":2016,"cited_by_count":14},{"year":2015,"cited_by_count":8},{"year":2014,"cited_by_count":10},{"year":2013,"cited_by_count":10},{"year":2012,"cited_by_count":5}],"updated_date":"2026-04-10T15:06:20.359241","created_date":"2025-10-10T00:00:00"}