{"id":"https://openalex.org/W2141925828","doi":"https://doi.org/10.1371/journal.pcbi.1000160","title":"The Rough Guide to In Silico Function Prediction, or How To Use Sequence and Structure Information To Predict Protein Function","display_name":"The Rough Guide to In Silico Function Prediction, or How To Use Sequence and Structure Information To Predict Protein Function","publication_year":2008,"publication_date":"2008-10-30","ids":{"openalex":"https://openalex.org/W2141925828","doi":"https://doi.org/10.1371/journal.pcbi.1000160","mag":"2141925828","pmid":"https://pubmed.ncbi.nlm.nih.gov/18974821"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pcbi.1000160","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1000160","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1000160&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Computational Biology","raw_type":"journal-article"},"type":"review","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1000160&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5056369160","display_name":"Marco Punta","orcid":"https://orcid.org/0000-0002-0050-0676"},"institutions":[{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]},{"id":"https://openalex.org/I4210096322","display_name":"New York Structural Biology Center","ror":"https://ror.org/00new7409","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210096322"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Marco Punta","raw_affiliation_strings":["Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA","Northeast Structural Genomics Consortium (NESG), Columbia University, New York, New York, United States of America","Department of Biochemistry and Molecular Biophysics, Columbia University, New York, New York, United States of America","Columbia University Center for Computational Biology and Bioinformatics (C2B2), New York, New York, United States of America"],"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA","institution_ids":["https://openalex.org/I78577930"]},{"raw_affiliation_string":"Northeast Structural Genomics Consortium (NESG), Columbia University, New York, New York, United States of America","institution_ids":["https://openalex.org/I4210096322","https://openalex.org/I78577930"]},{"raw_affiliation_string":"Department of Biochemistry and Molecular Biophysics, Columbia University, New York, New York, United States of America","institution_ids":["https://openalex.org/I78577930"]},{"raw_affiliation_string":"Columbia University Center for Computational Biology and Bioinformatics (C2B2), New York, New York, United States of America","institution_ids":["https://openalex.org/I78577930"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5104206666","display_name":"Yanay Ofran","orcid":null},"institutions":[{"id":"https://openalex.org/I13955877","display_name":"Bar-Ilan University","ror":"https://ror.org/03kgsv495","country_code":"IL","type":"education","lineage":["https://openalex.org/I13955877"]}],"countries":["IL"],"is_corresponding":true,"raw_author_name":"Yanay Ofran","raw_affiliation_strings":["The Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel"],"affiliations":[{"raw_affiliation_string":"The Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel","institution_ids":["https://openalex.org/I13955877"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5104206666"],"corresponding_institution_ids":["https://openalex.org/I13955877"],"apc_list":{"value":2655,"currency":"USD","value_usd":2655},"apc_paid":{"value":2655,"currency":"USD","value_usd":2655},"fwci":4.9792,"has_fulltext":true,"cited_by_count":111,"citation_normalized_percentile":{"value":0.96067399,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":100},"biblio":{"volume":"4","issue":"10","first_page":"e1000160","last_page":"e1000160"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9988999962806702,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/protein-function-prediction","display_name":"Protein function prediction","score":0.7869939208030701},{"id":"https://openalex.org/keywords/function","display_name":"Function (biology)","score":0.6822754740715027},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6274243593215942},{"id":"https://openalex.org/keywords/in-silico","display_name":"In silico","score":0.5812508463859558},{"id":"https://openalex.org/keywords/context","display_name":"Context (archaeology)","score":0.5695220828056335},{"id":"https://openalex.org/keywords/sequence","display_name":"Sequence (biology)","score":0.5555845499038696},{"id":"https://openalex.org/keywords/benchmarking","display_name":"Benchmarking","score":0.5516847968101501},{"id":"https://openalex.org/keywords/protein-structure-prediction","display_name":"Protein structure prediction","score":0.5015769004821777},{"id":"https://openalex.org/keywords/protein-function","display_name":"Protein function","score":0.49091845750808716},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.47711923718452454},{"id":"https://openalex.org/keywords/protein-structure-database","display_name":"Protein structure database","score":0.46535593271255493},{"id":"https://openalex.org/keywords/task","display_name":"Task (project management)","score":0.4405418932437897},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.41931819915771484},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.40012314915657043},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.36997753381729126},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.3473131060600281},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.3380500376224518},{"id":"https://openalex.org/keywords/protein-structure","display_name":"Protein structure","score":0.3090479373931885},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.24721938371658325},{"id":"https://openalex.org/keywords/sequence-database","display_name":"Sequence database","score":0.17545750737190247},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.13138073682785034},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.10173165798187256}],"concepts":[{"id":"https://openalex.org/C207060522","wikidata":"https://www.wikidata.org/wiki/Q7251473","display_name":"Protein function prediction","level":4,"score":0.7869939208030701},{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.6822754740715027},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6274243593215942},{"id":"https://openalex.org/C2775905019","wikidata":"https://www.wikidata.org/wiki/Q192572","display_name":"In silico","level":3,"score":0.5812508463859558},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.5695220828056335},{"id":"https://openalex.org/C2778112365","wikidata":"https://www.wikidata.org/wiki/Q3511065","display_name":"Sequence (biology)","level":2,"score":0.5555845499038696},{"id":"https://openalex.org/C86251818","wikidata":"https://www.wikidata.org/wiki/Q816754","display_name":"Benchmarking","level":2,"score":0.5516847968101501},{"id":"https://openalex.org/C18051474","wikidata":"https://www.wikidata.org/wiki/Q899656","display_name":"Protein structure prediction","level":3,"score":0.5015769004821777},{"id":"https://openalex.org/C2986374874","wikidata":"https://www.wikidata.org/wiki/Q8054","display_name":"Protein function","level":3,"score":0.49091845750808716},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.47711923718452454},{"id":"https://openalex.org/C136475424","wikidata":"https://www.wikidata.org/wiki/Q7251500","display_name":"Protein structure database","level":4,"score":0.46535593271255493},{"id":"https://openalex.org/C2780451532","wikidata":"https://www.wikidata.org/wiki/Q759676","display_name":"Task (project management)","level":2,"score":0.4405418932437897},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.41931819915771484},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.40012314915657043},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.36997753381729126},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.3473131060600281},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.3380500376224518},{"id":"https://openalex.org/C47701112","wikidata":"https://www.wikidata.org/wiki/Q735188","display_name":"Protein structure","level":2,"score":0.3090479373931885},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.24721938371658325},{"id":"https://openalex.org/C41584329","wikidata":"https://www.wikidata.org/wiki/Q175902","display_name":"Sequence database","level":3,"score":0.17545750737190247},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.13138073682785034},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.10173165798187256},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C162853370","wikidata":"https://www.wikidata.org/wiki/Q39809","display_name":"Marketing","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C144133560","wikidata":"https://www.wikidata.org/wiki/Q4830453","display_name":"Business","level":0,"score":0.0},{"id":"https://openalex.org/C201995342","wikidata":"https://www.wikidata.org/wiki/Q682496","display_name":"Systems engineering","level":1,"score":0.0},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D005544","descriptor_name":"Forecasting","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D005544","descriptor_name":"Forecasting","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D005544","descriptor_name":"Forecasting","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D013329","descriptor_name":"Structure-Activity Relationship","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013329","descriptor_name":"Structure-Activity Relationship","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013329","descriptor_name":"Structure-Activity Relationship","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1371/journal.pcbi.1000160","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1000160","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1000160&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Computational Biology","raw_type":"journal-article"},{"id":"pmid:18974821","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18974821","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS computational biology","raw_type":null},{"id":"pmh:oai:doaj.org/article:cc49084199dc4c1da635c0401891efd3","is_oa":true,"landing_page_url":"https://doaj.org/article/cc49084199dc4c1da635c0401891efd3","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Computational Biology, Vol 4, Iss 10, p e1000160 (2008)","raw_type":"article"},{"id":"pmh:oai:figshare.com:article/149251","is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/The_Rough_Guide_to_In_Silico_Function_Prediction_or_How_To_Use_Sequence_and_Structure_Information_To_Predict_Protein_Function/149251","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"},{"id":"pmh:oai:pubmedcentral.nih.gov:2518264","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2518264","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Comput Biol","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1371/journal.pcbi.1000160","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1000160","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1000160&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Computational Biology","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G3497591915","display_name":null,"funder_award_id":"(NIH)","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2141925828.pdf","grobid_xml":"https://content.openalex.org/works/W2141925828.grobid-xml"},"referenced_works_count":96,"referenced_works":["https://openalex.org/W1530397352","https://openalex.org/W1531116739","https://openalex.org/W1572961809","https://openalex.org/W1933777541","https://openalex.org/W1964640688","https://openalex.org/W1969080446","https://openalex.org/W1971099088","https://openalex.org/W1971894358","https://openalex.org/W1979132333","https://openalex.org/W1983259744","https://openalex.org/W1986154009","https://openalex.org/W1986969007","https://openalex.org/W1987856282","https://openalex.org/W1990453950","https://openalex.org/W1993772187","https://openalex.org/W1996599952","https://openalex.org/W2004994701","https://openalex.org/W2006211612","https://openalex.org/W2015546050","https://openalex.org/W2029574260","https://openalex.org/W2029667189","https://openalex.org/W2034045953","https://openalex.org/W2036662864","https://openalex.org/W2044465665","https://openalex.org/W2047819993","https://openalex.org/W2054683843","https://openalex.org/W2055033601","https://openalex.org/W2055509168","https://openalex.org/W2056197139","https://openalex.org/W2058440547","https://openalex.org/W2061033843","https://openalex.org/W2062761272","https://openalex.org/W2066162606","https://openalex.org/W2071788088","https://openalex.org/W2077388126","https://openalex.org/W2082605863","https://openalex.org/W2086568203","https://openalex.org/W2087455496","https://openalex.org/W2089047063","https://openalex.org/W2089085945","https://openalex.org/W2089939121","https://openalex.org/W2098223336","https://openalex.org/W2099389777","https://openalex.org/W2100018338","https://openalex.org/W2100320834","https://openalex.org/W2100494857","https://openalex.org/W2101780178","https://openalex.org/W2102333330","https://openalex.org/W2103150692","https://openalex.org/W2106882534","https://openalex.org/W2108067237","https://openalex.org/W2108187446","https://openalex.org/W2109681606","https://openalex.org/W2111127373","https://openalex.org/W2115595474","https://openalex.org/W2117019496","https://openalex.org/W2117077088","https://openalex.org/W2123858481","https://openalex.org/W2128049108","https://openalex.org/W2128402268","https://openalex.org/W2128533758","https://openalex.org/W2129261098","https://openalex.org/W2130479394","https://openalex.org/W2130925474","https://openalex.org/W2133340731","https://openalex.org/W2137146016","https://openalex.org/W2137345862","https://openalex.org/W2137991504","https://openalex.org/W2139942857","https://openalex.org/W2140407975","https://openalex.org/W2142757818","https://openalex.org/W2144670399","https://openalex.org/W2144998676","https://openalex.org/W2147285856","https://openalex.org/W2149822709","https://openalex.org/W2151043202","https://openalex.org/W2151571712","https://openalex.org/W2152875974","https://openalex.org/W2153294290","https://openalex.org/W2153463820","https://openalex.org/W2158714788","https://openalex.org/W2159280460","https://openalex.org/W2160297538","https://openalex.org/W2161062388","https://openalex.org/W2167188257","https://openalex.org/W2167574472","https://openalex.org/W2168514491","https://openalex.org/W2169043568","https://openalex.org/W2171602500","https://openalex.org/W2413865546","https://openalex.org/W2501634941","https://openalex.org/W2683236244","https://openalex.org/W2916193864","https://openalex.org/W4211054902","https://openalex.org/W4240629327","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W2593264178","https://openalex.org/W2181530468","https://openalex.org/W2470147982","https://openalex.org/W2185518315","https://openalex.org/W4387310732","https://openalex.org/W1504467230","https://openalex.org/W2043066834","https://openalex.org/W2039679484","https://openalex.org/W4322579338","https://openalex.org/W2398461637"],"abstract_inverted_index":{"The":[0],"Rough":[1],"Guide":[2],"to":[3],"In":[4],"Silico":[5],"Function":[6,19],"Prediction,":[7],"or":[8],"How":[9],"To":[10,16],"Use":[11],"Sequence":[12],"and":[13],"Structure":[14],"Information":[15],"Predict":[17],"Protein":[18]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":7},{"year":2019,"cited_by_count":7},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":11},{"year":2014,"cited_by_count":9},{"year":2013,"cited_by_count":14},{"year":2012,"cited_by_count":7}],"updated_date":"2026-04-21T08:09:41.155169","created_date":"2025-10-10T00:00:00"}