{"id":"https://openalex.org/W2142550540","doi":"https://doi.org/10.1371/journal.pcbi.1000085","title":"Silent Synapses, LTP, and the Indirect Parallel-Fibre Pathway: Computational Consequences of Optimal Cerebellar Noise-Processing","display_name":"Silent Synapses, LTP, and the Indirect Parallel-Fibre Pathway: Computational Consequences of Optimal Cerebellar Noise-Processing","publication_year":2008,"publication_date":"2008-05-22","ids":{"openalex":"https://openalex.org/W2142550540","doi":"https://doi.org/10.1371/journal.pcbi.1000085","mag":"2142550540","pmid":"https://pubmed.ncbi.nlm.nih.gov/18497864"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pcbi.1000085","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1000085","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1000085&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Computational Biology","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1000085&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5039306079","display_name":"John Porrill","orcid":null},"institutions":[{"id":"https://openalex.org/I91136226","display_name":"University of Sheffield","ror":"https://ror.org/05krs5044","country_code":"GB","type":"education","lineage":["https://openalex.org/I91136226"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"John Porrill","raw_affiliation_strings":["Department of Psychology, Sheffield University, Sheffield, United Kingdom. j.porrill@sheffield.ac.uk","Department of Psychology, Sheffield University, Sheffield, United Kingdom"],"affiliations":[{"raw_affiliation_string":"Department of Psychology, Sheffield University, Sheffield, United Kingdom. j.porrill@sheffield.ac.uk","institution_ids":["https://openalex.org/I91136226"]},{"raw_affiliation_string":"Department of Psychology, Sheffield University, Sheffield, United Kingdom","institution_ids":["https://openalex.org/I91136226"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5005722522","display_name":"Paul Dean","orcid":"https://orcid.org/0000-0003-3257-620X"},"institutions":[{"id":"https://openalex.org/I91136226","display_name":"University of Sheffield","ror":"https://ror.org/05krs5044","country_code":"GB","type":"education","lineage":["https://openalex.org/I91136226"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Paul Dean","raw_affiliation_strings":["Department of Psychology, Sheffield University, Sheffield, United Kingdom"],"affiliations":[{"raw_affiliation_string":"Department of Psychology, Sheffield University, Sheffield, United Kingdom","institution_ids":["https://openalex.org/I91136226"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5039306079"],"corresponding_institution_ids":["https://openalex.org/I91136226"],"apc_list":{"value":2655,"currency":"USD","value_usd":2655},"apc_paid":{"value":2655,"currency":"USD","value_usd":2655},"fwci":2.6601,"has_fulltext":true,"cited_by_count":31,"citation_normalized_percentile":{"value":0.88695741,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"4","issue":"5","first_page":"e1000085","last_page":"e1000085"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10542","display_name":"Vestibular and auditory disorders","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10542","display_name":"Vestibular and auditory disorders","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10427","display_name":"Visual perception and processing mechanisms","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10250","display_name":"Glaucoma and retinal disorders","score":0.9854000210762024,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/purkinje-cell","display_name":"Purkinje cell","score":0.7282280325889587},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.6439813375473022},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6227049231529236},{"id":"https://openalex.org/keywords/parallel-fiber","display_name":"Parallel fiber","score":0.5799086093902588},{"id":"https://openalex.org/keywords/noise","display_name":"Noise (video)","score":0.5776023864746094},{"id":"https://openalex.org/keywords/context","display_name":"Context (archaeology)","score":0.55308598279953},{"id":"https://openalex.org/keywords/learning-rule","display_name":"Learning rule","score":0.486270546913147},{"id":"https://openalex.org/keywords/synaptic-weight","display_name":"Synaptic weight","score":0.4683762192726135},{"id":"https://openalex.org/keywords/computational-model","display_name":"Computational model","score":0.45310208201408386},{"id":"https://openalex.org/keywords/filter","display_name":"Filter (signal processing)","score":0.4361090660095215},{"id":"https://openalex.org/keywords/cerebellum","display_name":"Cerebellum","score":0.40000802278518677},{"id":"https://openalex.org/keywords/biological-system","display_name":"Biological system","score":0.3552662134170532},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.32379990816116333},{"id":"https://openalex.org/keywords/artificial-neural-network","display_name":"Artificial neural network","score":0.2928743362426758},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.21878427267074585}],"concepts":[{"id":"https://openalex.org/C2778472085","wikidata":"https://www.wikidata.org/wiki/Q1570272","display_name":"Purkinje cell","level":3,"score":0.7282280325889587},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.6439813375473022},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6227049231529236},{"id":"https://openalex.org/C2778058767","wikidata":"https://www.wikidata.org/wiki/Q5064084","display_name":"Parallel fiber","level":4,"score":0.5799086093902588},{"id":"https://openalex.org/C99498987","wikidata":"https://www.wikidata.org/wiki/Q2210247","display_name":"Noise (video)","level":3,"score":0.5776023864746094},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.55308598279953},{"id":"https://openalex.org/C2779127903","wikidata":"https://www.wikidata.org/wiki/Q6510194","display_name":"Learning rule","level":3,"score":0.486270546913147},{"id":"https://openalex.org/C66949984","wikidata":"https://www.wikidata.org/wiki/Q7662043","display_name":"Synaptic weight","level":3,"score":0.4683762192726135},{"id":"https://openalex.org/C66024118","wikidata":"https://www.wikidata.org/wiki/Q1122506","display_name":"Computational model","level":2,"score":0.45310208201408386},{"id":"https://openalex.org/C106131492","wikidata":"https://www.wikidata.org/wiki/Q3072260","display_name":"Filter (signal processing)","level":2,"score":0.4361090660095215},{"id":"https://openalex.org/C2779652256","wikidata":"https://www.wikidata.org/wiki/Q130983","display_name":"Cerebellum","level":2,"score":0.40000802278518677},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.3552662134170532},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.32379990816116333},{"id":"https://openalex.org/C50644808","wikidata":"https://www.wikidata.org/wiki/Q192776","display_name":"Artificial neural network","level":2,"score":0.2928743362426758},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.21878427267074585},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.0},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.0},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002531","descriptor_name":"Cerebellum","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D002531","descriptor_name":"Cerebellum","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D002531","descriptor_name":"Cerebellum","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008959","descriptor_name":"Models, Neurological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008959","descriptor_name":"Models, Neurological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008959","descriptor_name":"Models, Neurological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009415","descriptor_name":"Nerve Net","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009415","descriptor_name":"Nerve Net","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009415","descriptor_name":"Nerve Net","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009433","descriptor_name":"Neural Inhibition","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009433","descriptor_name":"Neural Inhibition","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009433","descriptor_name":"Neural Inhibition","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009434","descriptor_name":"Neural Pathways","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009434","descriptor_name":"Neural Pathways","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009434","descriptor_name":"Neural Pathways","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009435","descriptor_name":"Synaptic Transmission","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009435","descriptor_name":"Synaptic Transmission","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009435","descriptor_name":"Synaptic Transmission","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D012027","descriptor_name":"Reflex, Vestibulo-Ocular","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D012027","descriptor_name":"Reflex, Vestibulo-Ocular","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D012027","descriptor_name":"Reflex, Vestibulo-Ocular","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D013269","descriptor_name":"Stochastic Processes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013269","descriptor_name":"Stochastic Processes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013269","descriptor_name":"Stochastic Processes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013569","descriptor_name":"Synapses","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D013569","descriptor_name":"Synapses","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D013569","descriptor_name":"Synapses","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017774","descriptor_name":"Long-Term Potentiation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D017774","descriptor_name":"Long-Term Potentiation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D017774","descriptor_name":"Long-Term Potentiation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false}],"locations_count":7,"locations":[{"id":"doi:10.1371/journal.pcbi.1000085","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1000085","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1000085&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Computational Biology","raw_type":"journal-article"},{"id":"pmid:18497864","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18497864","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS computational biology","raw_type":null},{"id":"pmh:oai:RePEc:plo:pcbi00:1000085","is_oa":false,"landing_page_url":"https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1000085","pdf_url":null,"source":{"id":"https://openalex.org/S4306401271","display_name":"RePEc: Research Papers in Economics","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I77793887","host_organization_name":"Federal Reserve Bank of St. Louis","host_organization_lineage":["https://openalex.org/I77793887"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"},{"id":"pmh:oai:doaj.org/article:7f8aed6839264c7fb0b31fb3a3d3b0f6","is_oa":true,"landing_page_url":"https://doaj.org/article/7f8aed6839264c7fb0b31fb3a3d3b0f6","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Computational Biology, Vol 4, Iss 5, p e1000085 (2008)","raw_type":"article"},{"id":"pmh:oai:eprints.whiterose.ac.uk:10033","is_oa":true,"landing_page_url":"http://eprints.whiterose.ac.uk/10033/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400854","display_name":"White Rose Research Online (University of Leeds, The University of Sheffield, University of York)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I2800616092","host_organization_name":"White Rose University Consortium","host_organization_lineage":["https://openalex.org/I2800616092"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"},{"id":"pmh:oai:figshare.com:article/150372","is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/Silent_Synapses_LTP_and_the_Indirect_Parallel_Fibre_Pathway_Computational_Consequences_of_Optimal_Cerebellar_Noise_Processing/150372","pdf_url":null,"source":{"id":"https://openalex.org/S4306400572","display_name":"OPAL (Open@LaTrobe) (La Trobe University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I196829312","host_organization_name":"La Trobe University","host_organization_lineage":["https://openalex.org/I196829312"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:2377154","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2377154","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Comput Biol","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1371/journal.pcbi.1000085","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1000085","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1000085&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Computational Biology","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1934935867","display_name":null,"funder_award_id":"Engineering and Physical Sciences R","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"}],"funders":[{"id":"https://openalex.org/F4320334627","display_name":"Engineering and Physical Sciences Research Council","ror":"https://ror.org/0439y7842"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2142550540.pdf","grobid_xml":"https://content.openalex.org/works/W2142550540.grobid-xml"},"referenced_works_count":64,"referenced_works":["https://openalex.org/W130083205","https://openalex.org/W143324445","https://openalex.org/W391578156","https://openalex.org/W1536929369","https://openalex.org/W1549445248","https://openalex.org/W1566686607","https://openalex.org/W1579583882","https://openalex.org/W1582681335","https://openalex.org/W1597173708","https://openalex.org/W1597739853","https://openalex.org/W1711688156","https://openalex.org/W1938385190","https://openalex.org/W1966104725","https://openalex.org/W1969090956","https://openalex.org/W1971319017","https://openalex.org/W1974343263","https://openalex.org/W1983329616","https://openalex.org/W1998794714","https://openalex.org/W1999726936","https://openalex.org/W2022504012","https://openalex.org/W2026758795","https://openalex.org/W2031402048","https://openalex.org/W2036244090","https://openalex.org/W2037989424","https://openalex.org/W2047993072","https://openalex.org/W2072365940","https://openalex.org/W2076845962","https://openalex.org/W2079502754","https://openalex.org/W2079668152","https://openalex.org/W2080667845","https://openalex.org/W2081206287","https://openalex.org/W2102586893","https://openalex.org/W2103019454","https://openalex.org/W2107458172","https://openalex.org/W2108091832","https://openalex.org/W2116376337","https://openalex.org/W2117908157","https://openalex.org/W2121527732","https://openalex.org/W2125001634","https://openalex.org/W2129679993","https://openalex.org/W2132494021","https://openalex.org/W2146891652","https://openalex.org/W2155051950","https://openalex.org/W2156636801","https://openalex.org/W2162765431","https://openalex.org/W2165941423","https://openalex.org/W2166889327","https://openalex.org/W2168986469","https://openalex.org/W2213919576","https://openalex.org/W2275389714","https://openalex.org/W2301250341","https://openalex.org/W2323839040","https://openalex.org/W2326588846","https://openalex.org/W2482792214","https://openalex.org/W2602425071","https://openalex.org/W2610857016","https://openalex.org/W2895674046","https://openalex.org/W4211188183","https://openalex.org/W4231160605","https://openalex.org/W4285719527","https://openalex.org/W6605815232","https://openalex.org/W6634744572","https://openalex.org/W6694195356","https://openalex.org/W7045474554"],"related_works":["https://openalex.org/W2088535609","https://openalex.org/W2018467166","https://openalex.org/W2145989555","https://openalex.org/W2037393500","https://openalex.org/W2413432173","https://openalex.org/W2548311580","https://openalex.org/W1992466275","https://openalex.org/W2078647142","https://openalex.org/W2171109922","https://openalex.org/W2142550540"],"abstract_inverted_index":{"Computational":[0],"analysis":[1],"of":[2,19,26,35,63,71,76,81,92,114,132,175,216,247,254],"neural":[3],"systems":[4],"is":[5,53,144,199,205,232],"at":[6],"its":[7,46,183],"most":[8],"useful":[9],"when":[10,99],"it":[11],"uncovers":[12],"principles":[13],"that":[14,45,56,125,159],"provide":[15],"a":[16,31,68,179,213],"unified":[17],"account":[18],"phenomena":[20],"across":[21],"multiple":[22],"scales":[23],"and":[24,50,55,60,119,134,157,250,252],"levels":[25],"description.":[27],"Here":[28],"we":[29],"analyse":[30],"widely":[32,233],"used":[33],"model":[34,80,104],"the":[36,57,77,82,90,106,112,129,149,171,244],"cerebellar":[37,83,150,220],"contribution":[38],"to":[39,42,48,85,110,196,206],"sensori-motor":[40,248,255],"learning":[41,108,221,256],"demonstrate":[43],"both":[44],"response":[47,75],"intrinsic":[49],"sensor":[51],"noise":[52,86,135],"optimal,":[54],"unexpected":[58],"synaptic":[59,161],"behavioural":[61,241],"consequences":[62],"this":[64],"optimality":[65,142],"can":[66],"explain":[67],"wide":[69],"range":[70],"experimental":[72],"data.":[73],"The":[74],"Marr-Albus":[78],"adaptive-filter":[79,103],"microcircuit":[84],"was":[87],"examined":[88],"in":[89,152,182,209],"context":[91],"vestibulo-ocular":[93],"reflex":[94],"calibration.":[95],"We":[96],"found":[97],"that,":[98],"appropriately":[100],"connected,":[101],"an":[102,168,189],"using":[105],"covariance":[107],"rule":[109],"adjust":[111],"weights":[113,162],"synapses":[115],"between":[116],"parallel":[117,139,194],"fibres":[118],"Purkinje":[120,197,202],"cells":[121],"learns":[122],"weight":[123],"values":[124],"are":[126],"optimal":[127,245],"given":[128],"relative":[130],"amount":[131],"signal":[133],"carried":[136],"by":[137],"each":[138],"fibre.":[140],"This":[141],"principle":[143],"consistent":[145],"with":[146],"data":[147],"on":[148],"role":[151],"smooth":[153],"pursuit":[154],"eye":[155],"movements,":[156],"predicts":[158],"many":[160],"must":[163,223],"be":[164,207],"very":[165],"small,":[166],"providing":[167],"explanation":[169],"for":[170],"experimentally":[172],"observed":[173],"preponderance":[174,180],"silent":[176,217],"synapses.":[177,218],"Such":[178],"has":[181],"turn":[184],"two":[185],"further":[186],"consequences.":[187],"First,":[188],"additional":[190],"inhibitory":[191],"pathway":[192],"from":[193,212],"fibre":[195],"cell":[198,203],"required":[200],"if":[201],"activity":[204],"altered":[208],"either":[210],"direction":[211],"starting":[214],"point":[215],"Second,":[219],"tasks":[222],"often":[224],"proceed":[225],"via":[226],"LTP,":[227],"rather":[228],"than":[229],"LTD":[230],"as":[231],"assumed.":[234],"Taken":[235],"together,":[236],"these":[237],"considerations":[238],"have":[239],"profound":[240],"consequences,":[242],"including":[243],"combination":[246],"information,":[249],"asymmetry":[251],"hysteresis":[253],"rates.":[257]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":4}],"updated_date":"2026-04-21T08:09:41.155169","created_date":"2025-10-10T00:00:00"}