{"id":"https://openalex.org/W2018567038","doi":"https://doi.org/10.1371/journal.pcbi.1000057","title":"Investigations of Oligonucleotide Usage Variance Within and Between Prokaryotes","display_name":"Investigations of Oligonucleotide Usage Variance Within and Between Prokaryotes","publication_year":2008,"publication_date":"2008-04-17","ids":{"openalex":"https://openalex.org/W2018567038","doi":"https://doi.org/10.1371/journal.pcbi.1000057","mag":"2018567038","pmid":"https://pubmed.ncbi.nlm.nih.gov/18421372"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pcbi.1000057","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1000057","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1000057&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Computational Biology","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1000057&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5049001926","display_name":"Jon Bohlin","orcid":"https://orcid.org/0000-0002-0992-1311"},"institutions":[{"id":"https://openalex.org/I4210164950","display_name":"Norwegian Veterinary Institute","ror":"https://ror.org/05m6y3182","country_code":"NO","type":"facility","lineage":["https://openalex.org/I4210164950"]}],"countries":["NO"],"is_corresponding":false,"raw_author_name":"Jon Bohlin","raw_affiliation_strings":["Norwegian School of Veterinary Science, Oslo, Norway","Norwegian School of Veterinary Science Oslo Norway"],"affiliations":[{"raw_affiliation_string":"Norwegian School of Veterinary Science, Oslo, Norway","institution_ids":["https://openalex.org/I4210164950"]},{"raw_affiliation_string":"Norwegian School of Veterinary Science Oslo Norway","institution_ids":["https://openalex.org/I4210164950"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070962912","display_name":"Eystein Skjerve","orcid":"https://orcid.org/0000-0001-9652-6952"},"institutions":[{"id":"https://openalex.org/I4210164950","display_name":"Norwegian Veterinary Institute","ror":"https://ror.org/05m6y3182","country_code":"NO","type":"facility","lineage":["https://openalex.org/I4210164950"]}],"countries":["NO"],"is_corresponding":false,"raw_author_name":"Eystein Skjerve","raw_affiliation_strings":["Norwegian School of Veterinary Science, Oslo, Norway","Norwegian School of Veterinary Science Oslo Norway"],"affiliations":[{"raw_affiliation_string":"Norwegian School of Veterinary Science, Oslo, Norway","institution_ids":["https://openalex.org/I4210164950"]},{"raw_affiliation_string":"Norwegian School of Veterinary Science Oslo Norway","institution_ids":["https://openalex.org/I4210164950"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5013526952","display_name":"David W. Ussery","orcid":"https://orcid.org/0000-0003-3632-5512"},"institutions":[{"id":"https://openalex.org/I96673099","display_name":"Technical University of Denmark","ror":"https://ror.org/04qtj9h94","country_code":"DK","type":"education","lineage":["https://openalex.org/I96673099"]}],"countries":["DK"],"is_corresponding":true,"raw_author_name":"David W. Ussery","raw_affiliation_strings":["Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, Lyngby, Denmark","Center for Biological Sequence Analysis Department of Systems Biology Technical University of Denmark Lyngby Denmark"],"affiliations":[{"raw_affiliation_string":"Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, Lyngby, Denmark","institution_ids":["https://openalex.org/I96673099"]},{"raw_affiliation_string":"Center for Biological Sequence Analysis Department of Systems Biology Technical University of Denmark Lyngby Denmark","institution_ids":["https://openalex.org/I96673099"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5013526952"],"corresponding_institution_ids":["https://openalex.org/I96673099"],"apc_list":{"value":2655,"currency":"USD","value_usd":2655},"apc_paid":{"value":2655,"currency":"USD","value_usd":2655},"fwci":5.1579,"has_fulltext":true,"cited_by_count":64,"citation_normalized_percentile":{"value":0.95654256,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":98},"biblio":{"volume":"4","issue":"4","first_page":"e1000057","last_page":"e1000057"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.9936000108718872,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.9936000108718872,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.993399977684021,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11048","display_name":"Bacteriophages and microbial interactions","score":0.9927999973297119,"subfield":{"id":"https://openalex.org/subfields/2303","display_name":"Ecology"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5701691508293152},{"id":"https://openalex.org/keywords/oligonucleotide","display_name":"Oligonucleotide","score":0.5059697031974792},{"id":"https://openalex.org/keywords/variance","display_name":"Variance (accounting)","score":0.45709696412086487},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.4313245117664337},{"id":"https://openalex.org/keywords/evolutionary-biology","display_name":"Evolutionary biology","score":0.36796844005584717},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.33729031682014465},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.25747963786125183},{"id":"https://openalex.org/keywords/dna","display_name":"DNA","score":0.11853596568107605}],"concepts":[{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5701691508293152},{"id":"https://openalex.org/C129312508","wikidata":"https://www.wikidata.org/wiki/Q133686","display_name":"Oligonucleotide","level":3,"score":0.5059697031974792},{"id":"https://openalex.org/C196083921","wikidata":"https://www.wikidata.org/wiki/Q7915758","display_name":"Variance (accounting)","level":2,"score":0.45709696412086487},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4313245117664337},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.36796844005584717},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.33729031682014465},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.25747963786125183},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.11853596568107605},{"id":"https://openalex.org/C144133560","wikidata":"https://www.wikidata.org/wiki/Q4830453","display_name":"Business","level":0,"score":0.0},{"id":"https://openalex.org/C121955636","wikidata":"https://www.wikidata.org/wiki/Q4116214","display_name":"Accounting","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D001482","descriptor_name":"Base Composition","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001482","descriptor_name":"Base Composition","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001482","descriptor_name":"Base Composition","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004269","descriptor_name":"DNA, Bacterial","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004269","descriptor_name":"DNA, Bacterial","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004269","descriptor_name":"DNA, Bacterial","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D008957","descriptor_name":"Models, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008957","descriptor_name":"Models, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008957","descriptor_name":"Models, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013045","descriptor_name":"Species Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013045","descriptor_name":"Species Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013045","descriptor_name":"Species Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014644","descriptor_name":"Genetic Variation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014644","descriptor_name":"Genetic Variation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014644","descriptor_name":"Genetic Variation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019143","descriptor_name":"Evolution, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019143","descriptor_name":"Evolution, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019143","descriptor_name":"Evolution, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019641","descriptor_name":"DNA, Archaeal","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D019641","descriptor_name":"DNA, Archaeal","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D019641","descriptor_name":"DNA, Archaeal","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false}],"locations_count":7,"locations":[{"id":"doi:10.1371/journal.pcbi.1000057","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1000057","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1000057&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Computational Biology","raw_type":"journal-article"},{"id":"pmid:18421372","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18421372","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS computational biology","raw_type":null},{"id":"pmh:oai:RePEc:plo:pcbi00:1000057","is_oa":false,"landing_page_url":"https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1000057","pdf_url":null,"source":{"id":"https://openalex.org/S4306401271","display_name":"RePEc: Research Papers in Economics","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I77793887","host_organization_name":"Federal Reserve Bank of St. Louis","host_organization_lineage":["https://openalex.org/I77793887"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"},{"id":"pmh:oai:doaj.org/article:5e824674797e4fe39c103bd0998ed941","is_oa":true,"landing_page_url":"https://doaj.org/article/5e824674797e4fe39c103bd0998ed941","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Computational Biology, Vol 4, Iss 4, p e1000057 (2008)","raw_type":"article"},{"id":"pmh:oai:figshare.com:article/150607","is_oa":true,"landing_page_url":"https://figshare.com/articles/Investigations_of_Oligonucleotide_Usage_Variance_Within_and_Between_Prokaryotes/150607","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"},{"id":"pmh:oai:pubmedcentral.nih.gov:2289840","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2289840","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Comput Biol","raw_type":"Text"},{"id":"pmh:oai:pure.atira.dk:publications/510fc3c7-809a-4504-a7c1-056f5a8a1da9","is_oa":true,"landing_page_url":"https://orbit.dtu.dk/en/publications/510fc3c7-809a-4504-a7c1-056f5a8a1da9","pdf_url":null,"source":{"id":"https://openalex.org/S4306400705","display_name":"Technical University of Denmark, DTU Orbit (Technical University of Denmark, DTU)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I96673099","host_organization_name":"Technical University of Denmark","host_organization_lineage":["https://openalex.org/I96673099"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bohlin , J , Skjerve , E & Ussery , D 2008 , ' Investigations of oligonucleotide usage variance within and between prokaryotes ' , P L o S Computational Biology (Online) , vol. 4 , no. 4 , pp. e1000057 . https://doi.org/10.1371/journal.pcbi.1000057","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1371/journal.pcbi.1000057","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1000057","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1000057&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Computational Biology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/7","score":0.5899999737739563,"display_name":"Affordable and clean energy"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2018567038.pdf","grobid_xml":"https://content.openalex.org/works/W2018567038.grobid-xml"},"referenced_works_count":21,"referenced_works":["https://openalex.org/W1548240020","https://openalex.org/W1589513205","https://openalex.org/W1968655962","https://openalex.org/W1988969077","https://openalex.org/W2018526864","https://openalex.org/W2033072260","https://openalex.org/W2039753810","https://openalex.org/W2067907709","https://openalex.org/W2085350879","https://openalex.org/W2086341363","https://openalex.org/W2088769939","https://openalex.org/W2105559365","https://openalex.org/W2105837214","https://openalex.org/W2110342329","https://openalex.org/W2126627383","https://openalex.org/W2162711333","https://openalex.org/W2169390856","https://openalex.org/W2582743722","https://openalex.org/W2993222596","https://openalex.org/W3198167246","https://openalex.org/W4241673276"],"related_works":["https://openalex.org/W2082860237","https://openalex.org/W2119695867","https://openalex.org/W2130076355","https://openalex.org/W1990804418","https://openalex.org/W1993764875","https://openalex.org/W2046158694","https://openalex.org/W2788277189","https://openalex.org/W2013243191","https://openalex.org/W2151865869","https://openalex.org/W2061542922"],"abstract_inverted_index":{"Oligonucleotide":[0,107],"usage":[1,17,108,136,196,219],"in":[2,48,99,104,117,128,134,166,192,197],"archaeal":[3],"and":[4,23,42,50,63,70,113,119,122,141,179,182,190,208,228,234],"bacterial":[5],"genomes":[6,101,115,186,210],"can":[7,82],"be":[8,83,156,213],"linked":[9],"to":[10,28,32,59,155,215],"a":[11],"number":[12],"of":[13,38,194],"properties,":[14],"including":[15],"codon":[16],"(trinucleotides),":[18],"DNA":[19,24,40,61,65,91,172],"base-stacking":[20],"energy":[21],"(dinucleotides),":[22],"structural":[25],"conformation":[26],"(di-":[27],"tetranucleotides).":[29],"We":[30],"wanted":[31],"assess":[33],"the":[34,75,167],"statistical":[35],"information":[36,98],"potential":[37],"different":[39],"'word-sizes'":[41],"explore":[43],"how":[44,64],"oligonucleotide":[45,57],"frequencies":[46,58],"differ":[47],"coding":[49,142,162],"non-coding":[51,129,148,198],"regions.":[52,130,149],"In":[53],"addition,":[54],"we":[55],"used":[56],"investigate":[60],"composition":[62],"sequence":[66],"patterns":[67],"change":[68],"within":[69,111,178,220],"between":[71,180,206],"prokaryotic":[72,80,90,100],"organisms.":[73],"Among":[74],"results":[76],"found":[77,154,176,205],"was":[78,125],"that":[79,89],"chromosomes":[81,169],"described":[84],"by":[85],"hexanucleotide":[86],"frequencies,":[87],"suggesting":[88],"is":[92,102],"predominantly":[93],"short":[94,105],"range":[95],"correlated,":[96],"i.e.,":[97],"encoded":[103],"oligonucleotides.":[106],"varied":[109],"more":[110,145,159,188,226],"AT-rich":[112,160,181,201,207],"host-associated":[114,221],"than":[116,147,161,200,231],"GC-rich":[118,183,185,209],"free-living":[120,232],"genomes,":[121],"this":[123],"variation":[124],"mainly":[126],"located":[127],"Bias":[131],"(selectional":[132],"pressure)":[133],"tetranucleotide":[135,195,218],"correlated":[137],"with":[138],"GC":[139],"content,":[140],"regions":[143,151,199],"were":[144,152,175,187],"biased":[146,191,230],"Non-coding":[150],"also":[153],"approximately":[157],"5.5%":[158],"regions,":[163],"on":[164,224],"average,":[165,225],"402":[168],"examined.":[170],"Pronounced":[171],"compositional":[173],"differences":[174,204],"both":[177],"genomes.":[184,202],"similar":[189],"terms":[193],"The":[203],"may":[211],"possibly":[212],"attributed":[214],"lifestyle,":[216],"since":[217],"bacteria":[222],"was,":[223],"dissimilar":[227],"less":[229],"archaea":[233],"bacteria.":[235]},"counts_by_year":[{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":3}],"updated_date":"2026-04-21T08:09:41.155169","created_date":"2025-10-10T00:00:00"}