{"id":"https://openalex.org/W2103014115","doi":"https://doi.org/10.1371/journal.pcbi.1000045","title":"The Dynamics of Human Body Weight Change","display_name":"The Dynamics of Human Body Weight Change","publication_year":2008,"publication_date":"2008-03-27","ids":{"openalex":"https://openalex.org/W2103014115","doi":"https://doi.org/10.1371/journal.pcbi.1000045","mag":"2103014115","pmid":"https://pubmed.ncbi.nlm.nih.gov/18369435"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pcbi.1000045","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1000045","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1000045&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Computational Biology","raw_type":"journal-article"},"type":"article","indexed_in":["arxiv","crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1000045&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5034374861","display_name":"Carson C. Chow","orcid":"https://orcid.org/0000-0003-1463-9553"},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210090567","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210090567"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Carson C. Chow","raw_affiliation_strings":["Laboratory of Biological Modeling, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, United States of America. carsonc@mail.nih.gov","Laboratory of Biological Modeling, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, United States of America"],"affiliations":[{"raw_affiliation_string":"Laboratory of Biological Modeling, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, United States of America. carsonc@mail.nih.gov","institution_ids":["https://openalex.org/I4210090567"]},{"raw_affiliation_string":"Laboratory of Biological Modeling, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, United States of America","institution_ids":["https://openalex.org/I4210090567","https://openalex.org/I1299303238"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5045179101","display_name":"Kevin D. Hall","orcid":"https://orcid.org/0000-0003-4062-3133"},"institutions":[{"id":"https://openalex.org/I4210090567","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210090567"]},{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kevin D. Hall","raw_affiliation_strings":["Laboratory of Biological Modeling, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, United States of America"],"affiliations":[{"raw_affiliation_string":"Laboratory of Biological Modeling, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, United States of America","institution_ids":["https://openalex.org/I4210090567","https://openalex.org/I1299303238"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5034374861"],"corresponding_institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210090567"],"apc_list":{"value":2655,"currency":"USD","value_usd":2655},"apc_paid":{"value":2655,"currency":"USD","value_usd":2655},"fwci":6.4098,"has_fulltext":true,"cited_by_count":147,"citation_normalized_percentile":{"value":0.97095635,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":100},"biblio":{"volume":"4","issue":"3","first_page":"e1000045","last_page":"e1000045"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12267","display_name":"Diet and metabolism studies","score":0.9979000091552734,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12267","display_name":"Diet and metabolism studies","score":0.9979000091552734,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11457","display_name":"Adipose Tissue and Metabolism","score":0.9747999906539917,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11520","display_name":"Advanced Thermodynamics and Statistical Mechanics","score":0.9312999844551086,"subfield":{"id":"https://openalex.org/subfields/3109","display_name":"Statistical and Nonlinear Physics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lean-body-mass","display_name":"Lean body mass","score":0.702983021736145},{"id":"https://openalex.org/keywords/composition","display_name":"Composition (language)","score":0.64078688621521},{"id":"https://openalex.org/keywords/body-weight","display_name":"Body weight","score":0.5377509593963623},{"id":"https://openalex.org/keywords/classification-of-obesity","display_name":"Classification of obesity","score":0.5075217485427856},{"id":"https://openalex.org/keywords/energy-expenditure","display_name":"Energy expenditure","score":0.5031628012657166},{"id":"https://openalex.org/keywords/obesity","display_name":"Obesity","score":0.4872835874557495},{"id":"https://openalex.org/keywords/energy","display_name":"Energy (signal processing)","score":0.4736926555633545},{"id":"https://openalex.org/keywords/fat-mass","display_name":"Fat mass","score":0.4461727738380432},{"id":"https://openalex.org/keywords/class","display_name":"Class (philosophy)","score":0.44498375058174133},{"id":"https://openalex.org/keywords/dynamics","display_name":"Dynamics (music)","score":0.4218471944332123},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.3554925322532654},{"id":"https://openalex.org/keywords/econometrics","display_name":"Econometrics","score":0.3474326729774475},{"id":"https://openalex.org/keywords/biological-system","display_name":"Biological system","score":0.3381992280483246},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.30700933933258057},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.23499128222465515},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.22967171669006348},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.22768527269363403},{"id":"https://openalex.org/keywords/endocrinology","display_name":"Endocrinology","score":0.22360432147979736},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.10450959205627441}],"concepts":[{"id":"https://openalex.org/C120863210","wikidata":"https://www.wikidata.org/wiki/Q17064264","display_name":"Lean body mass","level":3,"score":0.702983021736145},{"id":"https://openalex.org/C40231798","wikidata":"https://www.wikidata.org/wiki/Q1333743","display_name":"Composition (language)","level":2,"score":0.64078688621521},{"id":"https://openalex.org/C147583825","wikidata":"https://www.wikidata.org/wiki/Q620876","display_name":"Body weight","level":2,"score":0.5377509593963623},{"id":"https://openalex.org/C111214947","wikidata":"https://www.wikidata.org/wiki/Q22907290","display_name":"Classification of obesity","level":4,"score":0.5075217485427856},{"id":"https://openalex.org/C2988147884","wikidata":"https://www.wikidata.org/wiki/Q5377024","display_name":"Energy expenditure","level":2,"score":0.5031628012657166},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.4872835874557495},{"id":"https://openalex.org/C186370098","wikidata":"https://www.wikidata.org/wiki/Q442787","display_name":"Energy (signal processing)","level":2,"score":0.4736926555633545},{"id":"https://openalex.org/C2993503589","wikidata":"https://www.wikidata.org/wiki/Q193583","display_name":"Fat mass","level":3,"score":0.4461727738380432},{"id":"https://openalex.org/C2777212361","wikidata":"https://www.wikidata.org/wiki/Q5127848","display_name":"Class (philosophy)","level":2,"score":0.44498375058174133},{"id":"https://openalex.org/C145912823","wikidata":"https://www.wikidata.org/wiki/Q113558","display_name":"Dynamics (music)","level":2,"score":0.4218471944332123},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.3554925322532654},{"id":"https://openalex.org/C149782125","wikidata":"https://www.wikidata.org/wiki/Q160039","display_name":"Econometrics","level":1,"score":0.3474326729774475},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.3381992280483246},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.30700933933258057},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.23499128222465515},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.22967171669006348},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.22768527269363403},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.22360432147979736},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.10450959205627441},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C19417346","wikidata":"https://www.wikidata.org/wiki/Q7922","display_name":"Pedagogy","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D001823","descriptor_name":"Body Composition","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001823","descriptor_name":"Body Composition","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001823","descriptor_name":"Body Composition","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004435","descriptor_name":"Eating","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004435","descriptor_name":"Eating","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004435","descriptor_name":"Eating","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004734","descriptor_name":"Energy Metabolism","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004734","descriptor_name":"Energy Metabolism","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004734","descriptor_name":"Energy Metabolism","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D015430","descriptor_name":"Weight Gain","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D015430","descriptor_name":"Weight Gain","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D015430","descriptor_name":"Weight Gain","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D015431","descriptor_name":"Weight Loss","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D015431","descriptor_name":"Weight Loss","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D015431","descriptor_name":"Weight Loss","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false}],"locations_count":7,"locations":[{"id":"doi:10.1371/journal.pcbi.1000045","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1000045","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1000045&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Computational Biology","raw_type":"journal-article"},{"id":"pmid:18369435","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18369435","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS computational biology","raw_type":null},{"id":"pmh:oai:arXiv.org:0802.3234","is_oa":true,"landing_page_url":"http://arxiv.org/abs/0802.3234","pdf_url":"https://arxiv.org/pdf/0802.3234","source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.282.7264","is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.282.7264","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/e0/45/PLoS_Comput_Biol_2008_Mar_28_4(3)_e1000045.tar.gz","raw_type":"text"},{"id":"pmh:oai:RePEc:plo:pcbi00:1000045","is_oa":false,"landing_page_url":"https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1000045","pdf_url":null,"source":{"id":"https://openalex.org/S4306401271","display_name":"RePEc: Research Papers in Economics","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I77793887","host_organization_name":"Federal Reserve Bank of St. Louis","host_organization_lineage":["https://openalex.org/I77793887"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"},{"id":"pmh:oai:doaj.org/article:9cfc121da06e4fbba059b1604d88b039","is_oa":true,"landing_page_url":"https://doaj.org/article/9cfc121da06e4fbba059b1604d88b039","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Computational Biology, Vol 4, Iss 3, p e1000045 (2008)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2266991","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2266991","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Comput Biol","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1371/journal.pcbi.1000045","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1000045","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1000045&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Computational Biology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/7","score":0.6499999761581421,"display_name":"Affordable and clean energy"}],"awards":[{"id":"https://openalex.org/G197008112","display_name":null,"funder_award_id":"NIDDK","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2103014115.pdf","grobid_xml":"https://content.openalex.org/works/W2103014115.grobid-xml"},"referenced_works_count":52,"referenced_works":["https://openalex.org/W619371579","https://openalex.org/W1602485996","https://openalex.org/W1805292997","https://openalex.org/W1860153958","https://openalex.org/W1876456565","https://openalex.org/W1886764071","https://openalex.org/W1966584590","https://openalex.org/W1967204943","https://openalex.org/W1970328019","https://openalex.org/W1970878235","https://openalex.org/W1982415909","https://openalex.org/W1987618018","https://openalex.org/W1989604805","https://openalex.org/W1989817267","https://openalex.org/W1996241503","https://openalex.org/W2001065815","https://openalex.org/W2002342267","https://openalex.org/W2005887695","https://openalex.org/W2007188765","https://openalex.org/W2008765853","https://openalex.org/W2010634840","https://openalex.org/W2023168948","https://openalex.org/W2029030701","https://openalex.org/W2032251708","https://openalex.org/W2050252451","https://openalex.org/W2075290042","https://openalex.org/W2077694393","https://openalex.org/W2086142565","https://openalex.org/W2087948696","https://openalex.org/W2088099561","https://openalex.org/W2089876099","https://openalex.org/W2114839770","https://openalex.org/W2121018654","https://openalex.org/W2122535362","https://openalex.org/W2127115822","https://openalex.org/W2132537160","https://openalex.org/W2142073340","https://openalex.org/W2142758757","https://openalex.org/W2148513036","https://openalex.org/W2148546165","https://openalex.org/W2164312912","https://openalex.org/W2165340329","https://openalex.org/W2287659764","https://openalex.org/W2316534927","https://openalex.org/W2431579615","https://openalex.org/W2525772635","https://openalex.org/W2563255176","https://openalex.org/W2605543710","https://openalex.org/W2739685101","https://openalex.org/W3175840793","https://openalex.org/W4241259977","https://openalex.org/W6936174250"],"related_works":["https://openalex.org/W2317413953","https://openalex.org/W2992629971","https://openalex.org/W4387062113","https://openalex.org/W2402890121","https://openalex.org/W2118234927","https://openalex.org/W2258096689","https://openalex.org/W2351857135","https://openalex.org/W2996429541","https://openalex.org/W2353004926","https://openalex.org/W2765377399"],"abstract_inverted_index":{"An":[0],"imbalance":[1],"between":[2,156],"energy":[3,6,52,136,139],"intake":[4,137],"and":[5,17,21,42,46,111,149,176],"expenditure":[7,140],"will":[8,35],"lead":[9],"to":[10,154],"a":[11,58,95],"change":[12],"in":[13,38,145],"body":[14,18,92,109,121,174],"weight":[15,73],"(mass)":[16],"composition":[19,93,110,122,175],"(fat":[20],"lean":[22],"masses).":[23],"A":[24],"quantitative":[25],"understanding":[26],"of":[27,44,61,71,81,91,129,134,169],"the":[28,40,62,68,87,105,108,117,120,167],"processes":[29],"involved,":[30],"which":[31],"currently":[32],"remains":[33],"lacking,":[34],"be":[36,99],"useful":[37],"determining":[39],"etiology":[41],"treatment":[43],"obesity":[45],"other":[47],"conditions":[48],"resulting":[49],"from":[50],"prolonged":[51],"imbalance.":[53],"Here,":[54],"we":[55],"show":[56,85],"that":[57,86,172],"mathematical":[59],"model":[60,147],"macronutrient":[63],"flux":[64],"balances":[65],"can":[66,98,123,141],"capture":[67],"long-term":[69],"dynamics":[70],"human":[72],"change;":[74],"all":[75],"previous":[76],"models":[77],"are":[78,113,152],"special":[79],"cases":[80],"this":[82,161],"model.":[83],"We":[84],"generic":[88],"dynamic":[89],"behavior":[90],"for":[94,166],"clamped":[96],"diet":[97],"divided":[100],"into":[101],"two":[102,158],"classes.":[103],"In":[104,116],"first":[106],"class,":[107,119],"mass":[112],"determined":[114],"uniquely.":[115],"second":[118],"exist":[124],"at":[125],"an":[126],"infinite":[127],"number":[128],"possible":[130],"states.":[131],"Surprisingly,":[132],"perturbations":[133],"dietary":[135],"or":[138],"give":[142],"identical":[143],"responses":[144],"both":[146],"classes,":[148],"existing":[150],"data":[151],"insufficient":[153],"distinguish":[155],"these":[157],"possibilities.":[159],"Nevertheless,":[160],"distinction":[162],"has":[163],"important":[164],"implications":[165],"efficacy":[168],"clinical":[170],"interventions":[171],"alter":[173],"mass.":[177]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":13},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":12},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":9},{"year":2016,"cited_by_count":8},{"year":2015,"cited_by_count":6},{"year":2014,"cited_by_count":13},{"year":2013,"cited_by_count":9},{"year":2012,"cited_by_count":12}],"updated_date":"2026-04-21T08:09:41.155169","created_date":"2025-10-10T00:00:00"}