{"id":"https://openalex.org/W2127745643","doi":"https://doi.org/10.1371/journal.pcbi.0030248","title":"Determinants of Protein Abundance and Translation Efficiency in S. cerevisiae","display_name":"Determinants of Protein Abundance and Translation Efficiency in S. cerevisiae","publication_year":2007,"publication_date":"2007-12-18","ids":{"openalex":"https://openalex.org/W2127745643","doi":"https://doi.org/10.1371/journal.pcbi.0030248","mag":"2127745643","pmid":"https://pubmed.ncbi.nlm.nih.gov/18159940"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pcbi.0030248","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.0030248","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.0030248&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Computational Biology","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.0030248&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5021278923","display_name":"Tamir Tuller","orcid":"https://orcid.org/0000-0003-4194-7068"},"institutions":[{"id":"https://openalex.org/I16391192","display_name":"Tel Aviv University","ror":"https://ror.org/04mhzgx49","country_code":"IL","type":"education","lineage":["https://openalex.org/I16391192"]}],"countries":["IL"],"is_corresponding":true,"raw_author_name":"Tamir Tuller","raw_affiliation_strings":["School of Computer Science, Tel Aviv University, Tel Aviv, Israel. tamirtul@post.tau.ac.il","Department of Molecular Microbiology and Biotechnology, Tel Aviv University, Tel Aviv, Israel","School of Computer Science, Tel Aviv University, Tel Aviv, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Computer Science, Tel Aviv University, Tel Aviv, Israel. tamirtul@post.tau.ac.il","institution_ids":["https://openalex.org/I16391192"]},{"raw_affiliation_string":"Department of Molecular Microbiology and Biotechnology, Tel Aviv University, Tel Aviv, Israel","institution_ids":["https://openalex.org/I16391192"]},{"raw_affiliation_string":"School of Computer Science, Tel Aviv University, Tel Aviv, Israel","institution_ids":["https://openalex.org/I16391192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032235572","display_name":"Martin Kupiec","orcid":"https://orcid.org/0000-0002-7934-3342"},"institutions":[{"id":"https://openalex.org/I16391192","display_name":"Tel Aviv University","ror":"https://ror.org/04mhzgx49","country_code":"IL","type":"education","lineage":["https://openalex.org/I16391192"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Martin Kupiec","raw_affiliation_strings":["Department of Molecular Microbiology and Biotechnology, Tel Aviv University, Tel Aviv, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Microbiology and Biotechnology, Tel Aviv University, Tel Aviv, Israel","institution_ids":["https://openalex.org/I16391192"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5063492133","display_name":"Eytan Ruppin","orcid":"https://orcid.org/0000-0002-7862-3940"},"institutions":[{"id":"https://openalex.org/I16391192","display_name":"Tel Aviv University","ror":"https://ror.org/04mhzgx49","country_code":"IL","type":"education","lineage":["https://openalex.org/I16391192"]}],"countries":["IL"],"is_corresponding":true,"raw_author_name":"Eytan Ruppin","raw_affiliation_strings":["","School of Computer Science, Tel Aviv University, Tel Aviv, Israel","School of Medicine, Tel Aviv University, Tel Aviv, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]},{"raw_affiliation_string":"School of Computer Science, Tel Aviv University, Tel Aviv, Israel","institution_ids":["https://openalex.org/I16391192"]},{"raw_affiliation_string":"School of Medicine, Tel Aviv University, Tel Aviv, Israel","institution_ids":["https://openalex.org/I16391192"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5021278923","https://openalex.org/A5063492133"],"corresponding_institution_ids":["https://openalex.org/I16391192"],"apc_list":{"value":2655,"currency":"USD","value_usd":2655},"apc_paid":{"value":2655,"currency":"USD","value_usd":2655},"fwci":2.3983,"has_fulltext":true,"cited_by_count":130,"citation_normalized_percentile":{"value":0.88840558,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":100},"biblio":{"volume":"3","issue":"12","first_page":"e248","last_page":"e248"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10497","display_name":"Fungal and yeast genetics research","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/schizosaccharomyces-pombe","display_name":"Schizosaccharomyces pombe","score":0.7283053994178772},{"id":"https://openalex.org/keywords/codon-usage-bias","display_name":"Codon usage bias","score":0.7110999226570129},{"id":"https://openalex.org/keywords/saccharomyces-cerevisiae","display_name":"Saccharomyces cerevisiae","score":0.6958515644073486},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.6879906058311462},{"id":"https://openalex.org/keywords/translation","display_name":"Translation (biology)","score":0.5513590574264526},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.5289067625999451},{"id":"https://openalex.org/keywords/abundance","display_name":"Abundance (ecology)","score":0.5269430875778198},{"id":"https://openalex.org/keywords/adaptation","display_name":"Adaptation (eye)","score":0.5250927209854126},{"id":"https://openalex.org/keywords/messenger-rna","display_name":"Messenger RNA","score":0.48141810297966003},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.4752647280693054},{"id":"https://openalex.org/keywords/translational-efficiency","display_name":"Translational efficiency","score":0.43936747312545776},{"id":"https://openalex.org/keywords/transfer-rna","display_name":"Transfer RNA","score":0.4373510479927063},{"id":"https://openalex.org/keywords/protein-biosynthesis","display_name":"Protein biosynthesis","score":0.4108804762363434},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.365642249584198},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.3640122413635254},{"id":"https://openalex.org/keywords/rna","display_name":"RNA","score":0.17591917514801025},{"id":"https://openalex.org/keywords/ecology","display_name":"Ecology","score":0.10761266946792603},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.08148765563964844}],"concepts":[{"id":"https://openalex.org/C2779429346","wikidata":"https://www.wikidata.org/wiki/Q2236682","display_name":"Schizosaccharomyces pombe","level":4,"score":0.7283053994178772},{"id":"https://openalex.org/C87253356","wikidata":"https://www.wikidata.org/wiki/Q1106472","display_name":"Codon usage bias","level":4,"score":0.7110999226570129},{"id":"https://openalex.org/C2777576037","wikidata":"https://www.wikidata.org/wiki/Q719725","display_name":"Saccharomyces cerevisiae","level":3,"score":0.6958515644073486},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6879906058311462},{"id":"https://openalex.org/C149364088","wikidata":"https://www.wikidata.org/wiki/Q185917","display_name":"Translation (biology)","level":4,"score":0.5513590574264526},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.5289067625999451},{"id":"https://openalex.org/C77077793","wikidata":"https://www.wikidata.org/wiki/Q336019","display_name":"Abundance (ecology)","level":2,"score":0.5269430875778198},{"id":"https://openalex.org/C139807058","wikidata":"https://www.wikidata.org/wiki/Q352374","display_name":"Adaptation (eye)","level":2,"score":0.5250927209854126},{"id":"https://openalex.org/C105580179","wikidata":"https://www.wikidata.org/wiki/Q188928","display_name":"Messenger RNA","level":3,"score":0.48141810297966003},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.4752647280693054},{"id":"https://openalex.org/C2775992057","wikidata":"https://www.wikidata.org/wiki/Q16956568","display_name":"Translational efficiency","level":5,"score":0.43936747312545776},{"id":"https://openalex.org/C153957851","wikidata":"https://www.wikidata.org/wiki/Q201448","display_name":"Transfer RNA","level":4,"score":0.4373510479927063},{"id":"https://openalex.org/C3675279","wikidata":"https://www.wikidata.org/wiki/Q211935","display_name":"Protein biosynthesis","level":2,"score":0.4108804762363434},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.365642249584198},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.3640122413635254},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.17591917514801025},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.10761266946792603},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.08148765563964844},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008957","descriptor_name":"Models, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008957","descriptor_name":"Models, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008957","descriptor_name":"Models, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D013223","descriptor_name":"Statistics as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013223","descriptor_name":"Statistics as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013223","descriptor_name":"Statistics as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014176","descriptor_name":"Protein Biosynthesis","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D014176","descriptor_name":"Protein Biosynthesis","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D014176","descriptor_name":"Protein Biosynthesis","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D029701","descriptor_name":"Saccharomyces cerevisiae Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D029701","descriptor_name":"Saccharomyces cerevisiae Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D029701","descriptor_name":"Saccharomyces cerevisiae Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1371/journal.pcbi.0030248","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.0030248","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.0030248&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Computational Biology","raw_type":"journal-article"},{"id":"pmid:18159940","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18159940","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS computational biology","raw_type":null},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.153.6462","is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.153.6462","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www.cs.tau.ac.il/~ruppin/tamir_ploscb.pdf","raw_type":"text"},{"id":"pmh:oai:doaj.org/article:7f8c8a93623240e8ad2f676d0deda9c1","is_oa":true,"landing_page_url":"https://doaj.org/article/7f8c8a93623240e8ad2f676d0deda9c1","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Computational Biology, Vol 3, Iss 12, p e248 (2007)","raw_type":"article"},{"id":"pmh:oai:figshare.com:article/153740","is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/Determinants_of_Protein_Abundance_and_Translation_Efficiency_in_S_cerevisiae_/153740","pdf_url":null,"source":{"id":"https://openalex.org/S4306402621","display_name":"INDIGO (University of Illinois at Chicago)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I39422238","host_organization_name":"University of Illinois Chicago","host_organization_lineage":["https://openalex.org/I39422238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"},{"id":"pmh:oai:pubmedcentral.nih.gov:2230678","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2230678","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Comput Biol","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1371/journal.pcbi.0030248","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.0030248","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.0030248&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Computational Biology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.6800000071525574,"display_name":"No poverty","id":"https://metadata.un.org/sdg/1"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320320947","display_name":"German-Israeli Foundation for Scientific Research and Development","ror":"https://ror.org/00tntzp09"},{"id":"https://openalex.org/F4320322252","display_name":"Israel Science Foundation","ror":"https://ror.org/04sazxf24"},{"id":"https://openalex.org/F4320322596","display_name":"Tel Aviv University","ror":"https://ror.org/04mhzgx49"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2127745643.pdf","grobid_xml":"https://content.openalex.org/works/W2127745643.grobid-xml"},"referenced_works_count":53,"referenced_works":["https://openalex.org/W1509714827","https://openalex.org/W1532136954","https://openalex.org/W1540550673","https://openalex.org/W1604959358","https://openalex.org/W1825157170","https://openalex.org/W1869299862","https://openalex.org/W1993009001","https://openalex.org/W1999390565","https://openalex.org/W2013947447","https://openalex.org/W2017057004","https://openalex.org/W2036799174","https://openalex.org/W2043347159","https://openalex.org/W2045830695","https://openalex.org/W2065120930","https://openalex.org/W2079493886","https://openalex.org/W2082782306","https://openalex.org/W2084459589","https://openalex.org/W2093772131","https://openalex.org/W2100471807","https://openalex.org/W2101345690","https://openalex.org/W2103091054","https://openalex.org/W2105762369","https://openalex.org/W2107363136","https://openalex.org/W2107804881","https://openalex.org/W2109281577","https://openalex.org/W2110065044","https://openalex.org/W2115228331","https://openalex.org/W2115749923","https://openalex.org/W2115883819","https://openalex.org/W2120807984","https://openalex.org/W2124309259","https://openalex.org/W2125204768","https://openalex.org/W2126519962","https://openalex.org/W2127754721","https://openalex.org/W2128572161","https://openalex.org/W2133636765","https://openalex.org/W2134541788","https://openalex.org/W2136316164","https://openalex.org/W2139956963","https://openalex.org/W2140863273","https://openalex.org/W2141018553","https://openalex.org/W2142437744","https://openalex.org/W2148342439","https://openalex.org/W2148598563","https://openalex.org/W2150566147","https://openalex.org/W2157058776","https://openalex.org/W2163963584","https://openalex.org/W2164954378","https://openalex.org/W2170778160","https://openalex.org/W2170949754","https://openalex.org/W4213265720","https://openalex.org/W4239029175","https://openalex.org/W4253759977"],"related_works":["https://openalex.org/W2064841107","https://openalex.org/W2415853957","https://openalex.org/W2151102421","https://openalex.org/W2887582884","https://openalex.org/W2123637623","https://openalex.org/W2752267826","https://openalex.org/W1937290499","https://openalex.org/W2803275252","https://openalex.org/W2096426615","https://openalex.org/W4308231998"],"abstract_inverted_index":{"The":[0,89],"translation":[1,161],"efficiency":[2],"of":[3,33,51,66,93,101,115,174],"most":[4],"Saccharomyces":[5],"cerevisiae":[6,98],"genes":[7],"remains":[8],"fairly":[9],"constant":[10],"across":[11,145],"poor":[12,146],"and":[13,27,58,77,100,147,160],"rich":[14,148],"growth":[15],"media.":[16],"This":[17,167],"observation":[18],"has":[19],"led":[20],"us":[21],"to":[22,28,182,205],"revisit":[23],"the":[24,30,54,59,121,136,183,187,191,201],"available":[25],"data":[26,50,76],"examine":[29],"potential":[31],"utility":[32],"a":[34,64,152,164,197],"protein":[35,71,80,123,142],"abundance":[36,72,81,91,124,143],"predictor":[37,45],"in":[38,83,95,163,180],"reinterpreting":[39],"existing":[40],"mRNA":[41,52,111,138],"expression":[42,112,117,139],"data.":[43],"Our":[44,176],"is":[46,169],"based":[47],"on":[48,74],"large-scale":[49],"levels,":[53],"tRNA":[55,188],"adaptation":[56,184,199],"index,":[57],"evolutionary":[60],"rate.":[61],"It":[62],"attains":[63],"correlation":[65],"0.76":[67],"with":[68],"experimentally":[69],"determined":[70],"levels":[73,82,92,125,144],"unseen":[75],"successfully":[78],"cross-predicts":[79],"another":[84],"yeast":[85],"species":[86],"(Schizosaccharomyces":[87],"pombe).":[88],"predicted":[90,122],"proteins":[94,194],"known":[96],"S.":[97],"complexes,":[99],"interacting":[102],"proteins,":[103],"are":[104,130],"significantly":[105],"more":[106,170],"coherent":[107],"than":[108],"their":[109,208],"corresponding":[110,137],"levels.":[113,140],"Analysis":[114],"gene":[116],"measurement":[118],"experiments":[119],"using":[120],"yields":[126],"new":[127],"insights":[128],"that":[129,179],"not":[131],"readily":[132],"discernable":[133],"when":[134],"clustering":[135],"Comparing":[141],"media,":[149],"we":[150],"find":[151],"general":[153],"trend":[154],"for":[155],"homeostatic":[156],"regulation":[157],"where":[158],"transcription":[159],"change":[162],"reciprocal":[165],"manner.":[166],"phenomenon":[168],"prominent":[171],"near":[172],"origins":[173],"replications.":[175],"analysis":[177],"shows":[178],"parallel":[181],"occurring":[185],"at":[186,200],"level":[189,204],"via":[190],"codon":[192],"bias,":[193],"do":[195],"undergo":[196],"complementary":[198],"amino":[202],"acid":[203],"further":[206],"increase":[207],"abundance.":[209]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":8},{"year":2018,"cited_by_count":8},{"year":2017,"cited_by_count":14},{"year":2016,"cited_by_count":7},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":12},{"year":2013,"cited_by_count":9},{"year":2012,"cited_by_count":15}],"updated_date":"2026-07-11T18:08:03.149640","created_date":"2025-10-10T00:00:00"}