{"id":"https://openalex.org/W2037122954","doi":"https://doi.org/10.1371/journal.pcbi.0020016","title":"Circadian Clocks Are Resounding in Peripheral Tissues","display_name":"Circadian Clocks Are Resounding in Peripheral Tissues","publication_year":2006,"publication_date":"2006-03-03","ids":{"openalex":"https://openalex.org/W2037122954","doi":"https://doi.org/10.1371/journal.pcbi.0020016","mag":"2037122954","pmid":"https://pubmed.ncbi.nlm.nih.gov/16532060"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pcbi.0020016","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.0020016","pdf_url":null,"source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Computational Biology","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1371/journal.pcbi.0020016","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5055434163","display_name":"Andrey Ptitsyn","orcid":"https://orcid.org/0000-0003-1196-8757"},"institutions":[{"id":"https://openalex.org/I103990859","display_name":"Pennington Biomedical Research Center","ror":"https://ror.org/040cnym54","country_code":"US","type":"facility","lineage":["https://openalex.org/I103990859"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andrey A Ptitsyn","raw_affiliation_strings":["Experimental Obesity Laboratory, Louisiana State University Pennington Biomedical Research Center, Baton Rouge, Louisiana, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Experimental Obesity Laboratory, Louisiana State University Pennington Biomedical Research Center, Baton Rouge, Louisiana, USA","institution_ids":["https://openalex.org/I103990859"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029342707","display_name":"Sanjin Zvonic","orcid":null},"institutions":[{"id":"https://openalex.org/I103990859","display_name":"Pennington Biomedical Research Center","ror":"https://ror.org/040cnym54","country_code":"US","type":"facility","lineage":["https://openalex.org/I103990859"]},{"id":"https://openalex.org/I121820613","display_name":"Louisiana State University","ror":"https://ror.org/05ect4e57","country_code":"US","type":"education","lineage":["https://openalex.org/I121820613"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sanjin Zvonic","raw_affiliation_strings":["Stem Cell Laboratory, Louisiana State University Pennington Biomedical Research Center, Baton Rouge, Louisiana, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stem Cell Laboratory, Louisiana State University Pennington Biomedical Research Center, Baton Rouge, Louisiana, United States of America","institution_ids":["https://openalex.org/I103990859","https://openalex.org/I121820613"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088027897","display_name":"Steven A. Conrad","orcid":"https://orcid.org/0000-0002-4014-969X"},"institutions":[{"id":"https://openalex.org/I81020160","display_name":"Louisiana State University Health Sciences Center Shreveport","ror":"https://ror.org/03151rh82","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I81020160"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Steven A Conrad","raw_affiliation_strings":["Departments of Bioinformatics and Computational Biology, Medicine, and Emergency Medicine, Louisiana State University Health Sciences Center, Shreveport, Louisiana, United States of America","Departments of Bioinformatics and Computational Biology, Medicine, and Emergency Medicine, Louisiana State University Health Sciences Center, Shreveport, Louisiana, United States of America,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Bioinformatics and Computational Biology, Medicine, and Emergency Medicine, Louisiana State University Health Sciences Center, Shreveport, Louisiana, United States of America","institution_ids":["https://openalex.org/I81020160"]},{"raw_affiliation_string":"Departments of Bioinformatics and Computational Biology, Medicine, and Emergency Medicine, Louisiana State University Health Sciences Center, Shreveport, Louisiana, United States of America,","institution_ids":["https://openalex.org/I81020160"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016700561","display_name":"L. Keith Scott","orcid":"https://orcid.org/0000-0001-7913-6338"},"institutions":[{"id":"https://openalex.org/I81020160","display_name":"Louisiana State University Health Sciences Center Shreveport","ror":"https://ror.org/03151rh82","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I81020160"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"L. Keith Scott","raw_affiliation_strings":["Departments of Bioinformatics and Computational Biology, Medicine, and Emergency Medicine, Louisiana State University Health Sciences Center, Shreveport, Louisiana, United States of America","Departments of Bioinformatics and Computational Biology, Medicine, and Emergency Medicine, Louisiana State University Health Sciences Center, Shreveport, Louisiana, United States of America,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Bioinformatics and Computational Biology, Medicine, and Emergency Medicine, Louisiana State University Health Sciences Center, Shreveport, Louisiana, United States of America","institution_ids":["https://openalex.org/I81020160"]},{"raw_affiliation_string":"Departments of Bioinformatics and Computational Biology, Medicine, and Emergency Medicine, Louisiana State University Health Sciences Center, Shreveport, Louisiana, United States of America,","institution_ids":["https://openalex.org/I81020160"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008448236","display_name":"Randall L. Mynatt","orcid":"https://orcid.org/0000-0003-4399-0019"},"institutions":[{"id":"https://openalex.org/I103990859","display_name":"Pennington Biomedical Research Center","ror":"https://ror.org/040cnym54","country_code":"US","type":"facility","lineage":["https://openalex.org/I103990859"]},{"id":"https://openalex.org/I121820613","display_name":"Louisiana State University","ror":"https://ror.org/05ect4e57","country_code":"US","type":"education","lineage":["https://openalex.org/I121820613"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Randall L Mynatt","raw_affiliation_strings":["Experimental Obesity Laboratory, Louisiana State University Pennington Biomedical Research Center, Baton Rouge, Louisiana, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Experimental Obesity Laboratory, Louisiana State University Pennington Biomedical Research Center, Baton Rouge, Louisiana, United States of America","institution_ids":["https://openalex.org/I103990859","https://openalex.org/I121820613"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5026038537","display_name":"Jeffrey M. Gimble","orcid":"https://orcid.org/0000-0002-4990-7418"},"institutions":[{"id":"https://openalex.org/I103990859","display_name":"Pennington Biomedical Research Center","ror":"https://ror.org/040cnym54","country_code":"US","type":"facility","lineage":["https://openalex.org/I103990859"]},{"id":"https://openalex.org/I121820613","display_name":"Louisiana State University","ror":"https://ror.org/05ect4e57","country_code":"US","type":"education","lineage":["https://openalex.org/I121820613"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Jeffrey M Gimble","raw_affiliation_strings":["","Department of Veterinary Clinical Sciences, Louisiana State University School of Veterinary Medicine, Baton Rouge, Louisiana, United States of America","Stem Cell Laboratory, Louisiana State University Pennington Biomedical Research Center, Baton Rouge, Louisiana, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]},{"raw_affiliation_string":"Department of Veterinary Clinical Sciences, Louisiana State University School of Veterinary Medicine, Baton Rouge, Louisiana, United States of America","institution_ids":["https://openalex.org/I121820613"]},{"raw_affiliation_string":"Stem Cell Laboratory, Louisiana State University Pennington Biomedical Research Center, Baton Rouge, Louisiana, United States of America","institution_ids":["https://openalex.org/I103990859","https://openalex.org/I121820613"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5026038537"],"corresponding_institution_ids":["https://openalex.org/I103990859","https://openalex.org/I121820613"],"apc_list":{"value":2655,"currency":"USD","value_usd":2655},"apc_paid":{"value":2655,"currency":"USD","value_usd":2655},"fwci":4.34,"has_fulltext":true,"cited_by_count":153,"citation_normalized_percentile":{"value":0.9572,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":100},"biblio":{"volume":"2","issue":"3","first_page":"e16","last_page":"e16"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10342","display_name":"Circadian rhythm and melatonin","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10342","display_name":"Circadian rhythm and melatonin","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10676","display_name":"Genetics, Aging, and Longevity in Model Organisms","score":0.9531000256538391,"subfield":{"id":"https://openalex.org/subfields/1302","display_name":"Aging"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12005","display_name":"Spaceflight effects on biology","score":0.9174000024795532,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/circadian-rhythm","display_name":"Circadian rhythm","score":0.8854037523269653},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.759745717048645},{"id":"https://openalex.org/keywords/gene-expression-profiling","display_name":"Gene expression profiling","score":0.5273270010948181},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.5249443054199219},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.5194844007492065},{"id":"https://openalex.org/keywords/transcriptome","display_name":"Transcriptome","score":0.47180452942848206},{"id":"https://openalex.org/keywords/adipose-tissue","display_name":"Adipose tissue","score":0.43369781970977783},{"id":"https://openalex.org/keywords/microarray-analysis-techniques","display_name":"Microarray analysis techniques","score":0.4117995500564575},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.3669241964817047},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.3667609393596649},{"id":"https://openalex.org/keywords/endocrinology","display_name":"Endocrinology","score":0.2847478985786438}],"concepts":[{"id":"https://openalex.org/C121446783","wikidata":"https://www.wikidata.org/wiki/Q208353","display_name":"Circadian rhythm","level":2,"score":0.8854037523269653},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.759745717048645},{"id":"https://openalex.org/C18431079","wikidata":"https://www.wikidata.org/wiki/Q1502169","display_name":"Gene expression profiling","level":4,"score":0.5273270010948181},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5249443054199219},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.5194844007492065},{"id":"https://openalex.org/C162317418","wikidata":"https://www.wikidata.org/wiki/Q252857","display_name":"Transcriptome","level":4,"score":0.47180452942848206},{"id":"https://openalex.org/C171089720","wikidata":"https://www.wikidata.org/wiki/Q193583","display_name":"Adipose tissue","level":2,"score":0.43369781970977783},{"id":"https://openalex.org/C8415881","wikidata":"https://www.wikidata.org/wiki/Q6839217","display_name":"Microarray analysis techniques","level":4,"score":0.4117995500564575},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3669241964817047},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3667609393596649},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.2847478985786438}],"mesh":[{"descriptor_ui":"D000273","descriptor_name":"Adipose Tissue","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000273","descriptor_name":"Adipose Tissue","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000273","descriptor_name":"Adipose Tissue","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002940","descriptor_name":"Circadian Rhythm","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002940","descriptor_name":"Circadian Rhythm","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002940","descriptor_name":"Circadian Rhythm","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009991","descriptor_name":"Oscillometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009991","descriptor_name":"Oscillometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009991","descriptor_name":"Oscillometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013269","descriptor_name":"Stochastic Processes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013269","descriptor_name":"Stochastic Processes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013269","descriptor_name":"Stochastic Processes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014158","descriptor_name":"Transcription, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014158","descriptor_name":"Transcription, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014158","descriptor_name":"Transcription, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":8,"locations":[{"id":"doi:10.1371/journal.pcbi.0020016","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.0020016","pdf_url":null,"source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Computational Biology","raw_type":"journal-article"},{"id":"pmid:16532060","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16532060","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS computational biology","raw_type":null},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.776.2203","is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.776.2203","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/d7/ef/pcbi.0020016.PMC1391918.pdf","raw_type":"text"},{"id":"pmh:oai:RePEc:plo:pcbi00:0020016","is_oa":false,"landing_page_url":"https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.0020016","pdf_url":null,"source":{"id":"https://openalex.org/S4306401271","display_name":"RePEc: Research Papers in Economics","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I77793887","host_organization_name":"Federal Reserve Bank of St. Louis","host_organization_lineage":["https://openalex.org/I77793887"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"},{"id":"pmh:oai:doaj.org/article:35af790b30624039a89321e5f80f4933","is_oa":true,"landing_page_url":"https://doaj.org/article/35af790b30624039a89321e5f80f4933","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Computational Biology, Vol 2, Iss 3, p e16 (2006)","raw_type":"article"},{"id":"pmh:oai:europepmc.org:2622014","is_oa":true,"landing_page_url":"http://europepmc.org/articles/PMC1391918","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:figshare.com:article/153006","is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/Circadian_Clocks_Are_Resounding_in_Peripheral_Tissues/153006","pdf_url":null,"source":{"id":"https://openalex.org/S4306402621","display_name":"INDIGO (University of Illinois at Chicago)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I39422238","host_organization_name":"University of Illinois Chicago","host_organization_lineage":["https://openalex.org/I39422238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"},{"id":"pmh:oai:pubmedcentral.nih.gov:1391918","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1391918","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Comput Biol","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1371/journal.pcbi.0020016","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.0020016","pdf_url":null,"source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Computational Biology","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":25,"referenced_works":["https://openalex.org/W1576302979","https://openalex.org/W1969222263","https://openalex.org/W1986599980","https://openalex.org/W2021654192","https://openalex.org/W2024493318","https://openalex.org/W2042316818","https://openalex.org/W2053069559","https://openalex.org/W2053818267","https://openalex.org/W2055328441","https://openalex.org/W2056265088","https://openalex.org/W2060925737","https://openalex.org/W2061364479","https://openalex.org/W2066183013","https://openalex.org/W2101600063","https://openalex.org/W2104290916","https://openalex.org/W2110065044","https://openalex.org/W2122135124","https://openalex.org/W2134314273","https://openalex.org/W2135657996","https://openalex.org/W2137712228","https://openalex.org/W2154514232","https://openalex.org/W2163899311","https://openalex.org/W2167008303","https://openalex.org/W2261285517","https://openalex.org/W2997000181"],"related_works":["https://openalex.org/W2102285747","https://openalex.org/W2073305407","https://openalex.org/W2183420549","https://openalex.org/W2012175027","https://openalex.org/W2081507994","https://openalex.org/W2077582941","https://openalex.org/W308751227","https://openalex.org/W1972696957","https://openalex.org/W2039699813","https://openalex.org/W2132193638"],"abstract_inverted_index":{"Circadian":[0],"rhythms":[1],"are":[2],"prevalent":[3],"in":[4,11,24,54,86,95,105,118,141,145,176],"most":[5],"organisms.":[6],"Even":[7],"the":[8,12,28,130,165,177,180,183,224],"smallest":[9],"disturbances":[10],"orchestration":[13],"of":[14,39,51,68,124,132,138,158,167,182,213,227],"circadian":[15,59,69,116,228],"gene":[16,70],"expression":[17,60,71,121,131],"patterns":[18],"among":[19],"different":[20,78],"tissues":[21,56,101,150],"can":[22],"result":[23],"functional":[25],"asynchrony,":[26],"at":[27,133],"organism":[29],"level,":[30],"and":[31,98,144,147,196,210,237],"may":[32,173],"to":[33,35,114,136,187,223,235],"contribute":[34],"a":[36,58,65,73,87,152],"wide":[37],"range":[38],"physiologic":[40],"disorders.":[41],"It":[42],"has":[43],"been":[44,84],"reported":[45],"that":[46,129,164,217],"as":[47,49,102,104],"many":[48],"5%-10%":[50],"transcribed":[52],"genes":[53,140,168],"peripheral":[55,79],"follow":[57,151],"pattern.":[61,155],"We":[62,107,215],"have":[63,83,108],"conducted":[64],"comprehensive":[66],"study":[67],"on":[72,201,230],"large":[74],"dataset":[75],"representing":[76],"three":[77,110],"tissues.":[80],"The":[81],"data":[82,127,159],"produced":[85],"large-scale":[88],"microarray":[89],"experiment":[90],"covering":[91],"replicate":[92],"daily":[93,153],"cycles":[94],"murine":[96],"white":[97,146],"brown":[99,148],"adipose":[100,149],"well":[103],"liver.":[106,178],"applied":[109],"alternative":[111],"algorithmic":[112],"approaches":[113],"identify":[115],"oscillation":[117,185],"time":[119],"series":[120],"profiles.":[122],"Analyses":[123],"our":[125],"own":[126],"indicate":[128,204],"least":[134],"7%":[135],"21%":[137],"active":[139],"mouse":[142],"liver,":[143],"oscillatory":[154,171],"Indeed,":[156],"analysis":[157],"from":[160],"other":[161],"laboratories":[162],"suggests":[163],"percentage":[166],"with":[169],"an":[170],"pattern":[172],"approach":[174],"50%":[175],"For":[179],"rest":[181],"genes,":[184],"appears":[186],"be":[188,221],"obscured":[189],"by":[190],"stochastic":[191],"noise.":[192],"Our":[193],"phase":[194],"classification":[195],"computer":[197],"simulation":[198],"studies":[199],"based":[200],"multiple":[202],"datasets":[203],"no":[205],"detectable":[206],"boundary":[207],"between":[208],"oscillating":[209],"non-oscillating":[211],"fractions":[212],"genes.":[214],"conclude":[216],"greater":[218],"attention":[219],"should":[220],"given":[222],"potential":[225],"influence":[226],"mechanisms":[229],"any":[231],"biological":[232],"pathway":[233],"related":[234],"metabolism":[236],"obesity.":[238]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":30},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":7},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":8},{"year":2014,"cited_by_count":9},{"year":2013,"cited_by_count":9},{"year":2012,"cited_by_count":11}],"updated_date":"2026-08-08T07:41:36.138363","created_date":"2025-10-10T00:00:00"}