{"id":"https://openalex.org/W2337203490","doi":"https://doi.org/10.12688/f1000research.8288.1","title":"MetaNetVar: Pipeline for applying network analysis tools for genomic variants analysis","display_name":"MetaNetVar: Pipeline for applying network analysis tools for genomic variants analysis","publication_year":2016,"publication_date":"2016-04-13","ids":{"openalex":"https://openalex.org/W2337203490","doi":"https://doi.org/10.12688/f1000research.8288.1","mag":"2337203490","pmid":"https://pubmed.ncbi.nlm.nih.gov/27158457"},"language":"en","primary_location":{"id":"doi:10.12688/f1000research.8288.1","is_oa":true,"landing_page_url":"https://doi.org/10.12688/f1000research.8288.1","pdf_url":"https://f1000research.com/articles/5-674/v1/pdf","source":{"id":"https://openalex.org/S4210239046","display_name":"F1000Research","issn_l":"2046-1402","issn":["2046-1402"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320357","host_organization_name":"Faculty of 1000","host_organization_lineage":["https://openalex.org/P4310320357"],"host_organization_lineage_names":["Faculty of 1000"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"F1000Research","raw_type":"journal-article"},"type":"preprint","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://f1000research.com/articles/5-674/v1/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5053458657","display_name":"Eric Moyer","orcid":"https://orcid.org/0000-0002-7742-1239"},"institutions":[{"id":"https://openalex.org/I4210109390","display_name":"National Center for Biotechnology Information","ror":"https://ror.org/02meqm098","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I2800548410","https://openalex.org/I4210109390"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Eric Moyer","raw_affiliation_strings":["National Center for Biotechnology Information, Bethesda, USA","National Center for Biotechnology Information, Bethesda"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Center for Biotechnology Information, Bethesda, USA","institution_ids":["https://openalex.org/I4210109390"]},{"raw_affiliation_string":"National Center for Biotechnology Information, Bethesda","institution_ids":["https://openalex.org/I4210109390"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018279853","display_name":"Megan Hastings Hagenauer","orcid":"https://orcid.org/0000-0002-3715-9475"},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Megan Hagenauer","raw_affiliation_strings":["Molecular, Behavioral Neuroscience Institute, University of Michigan, Ann Arbor, USA","Molecular, Behavioral Neuroscience Institute, University of Michigan, Ann Arbor"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Molecular, Behavioral Neuroscience Institute, University of Michigan, Ann Arbor, USA","institution_ids":["https://openalex.org/I27837315"]},{"raw_affiliation_string":"Molecular, Behavioral Neuroscience Institute, University of Michigan, Ann Arbor","institution_ids":["https://openalex.org/I27837315"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073113593","display_name":"Matthew Lesko","orcid":"https://orcid.org/0000-0001-5403-2612"},"institutions":[{"id":"https://openalex.org/I4210109390","display_name":"National Center for Biotechnology Information","ror":"https://ror.org/02meqm098","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I2800548410","https://openalex.org/I4210109390"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Matthew Lesko","raw_affiliation_strings":["National Center for Biotechnology Information, National Library of Medicine, Bethesda, USA","National Center for Biotechnology Information, National Library of Medicine, Bethesda"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Center for Biotechnology Information, National Library of Medicine, Bethesda, USA","institution_ids":["https://openalex.org/I4210109390"]},{"raw_affiliation_string":"National Center for Biotechnology Information, National Library of Medicine, Bethesda","institution_ids":["https://openalex.org/I4210109390"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078910156","display_name":"Felix Francis","orcid":null},"institutions":[{"id":"https://openalex.org/I86501945","display_name":"University of Delaware","ror":"https://ror.org/01sbq1a82","country_code":"US","type":"education","lineage":["https://openalex.org/I86501945"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Felix Francis","raw_affiliation_strings":["Bioinformatics and Systems Biology program, University of Delaware, Newark, USA","Bioinformatics and Systems Biology program, University of Delaware, Newark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioinformatics and Systems Biology program, University of Delaware, Newark, USA","institution_ids":["https://openalex.org/I86501945"]},{"raw_affiliation_string":"Bioinformatics and Systems Biology program, University of Delaware, Newark","institution_ids":["https://openalex.org/I86501945"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022859331","display_name":"Oscar Rodriguez","orcid":null},"institutions":[{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Oscar Rodriguez","raw_affiliation_strings":["Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, USA","Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, USA","institution_ids":["https://openalex.org/I98704320"]},{"raw_affiliation_string":"Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York","institution_ids":["https://openalex.org/I98704320"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022793691","display_name":"Vijayaraj Nagarajan","orcid":null},"institutions":[{"id":"https://openalex.org/I4210134534","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210134534"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Vijayaraj Nagarajan","raw_affiliation_strings":["Bioinformatics and Computational Biosciences Branch, National Institute of Allergy and Infectious Diseases, National Institute of Mental Health, Bethesda, USA","Bioinformatics and Computational Biosciences Branch, National Institute of Allergy and Infectious Diseases, National Institute of Mental Health, Bethesda"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioinformatics and Computational Biosciences Branch, National Institute of Allergy and Infectious Diseases, National Institute of Mental Health, Bethesda, USA","institution_ids":["https://openalex.org/I4210134534"]},{"raw_affiliation_string":"Bioinformatics and Computational Biosciences Branch, National Institute of Allergy and Infectious Diseases, National Institute of Mental Health, Bethesda","institution_ids":["https://openalex.org/I4210134534"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046553003","display_name":"Vojtech Huser","orcid":"https://orcid.org/0000-0002-0709-6573"},"institutions":[{"id":"https://openalex.org/I2800548410","display_name":"United States National Library of Medicine","ror":"https://ror.org/0060t0j89","country_code":"US","type":"archive","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I2800548410"]},{"id":"https://openalex.org/I4210109390","display_name":"National Center for Biotechnology Information","ror":"https://ror.org/02meqm098","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I2800548410","https://openalex.org/I4210109390"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Vojtech Huser","raw_affiliation_strings":["Lister Hill National Center for Biomedical Communications, National Library of Medicine, National Institute of Mental Health, Bethesda, USA","Lister Hill National Center for Biomedical Communications, National Library of Medicine, National Institute of Mental Health, Bethesda"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lister Hill National Center for Biomedical Communications, National Library of Medicine, National Institute of Mental Health, Bethesda, USA","institution_ids":["https://openalex.org/I4210109390","https://openalex.org/I2800548410"]},{"raw_affiliation_string":"Lister Hill National Center for Biomedical Communications, National Library of Medicine, National Institute of Mental Health, Bethesda","institution_ids":["https://openalex.org/I4210109390"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5070603357","display_name":"Ben Busby","orcid":"https://orcid.org/0000-0001-5267-4988"},"institutions":[{"id":"https://openalex.org/I4210109390","display_name":"National Center for Biotechnology Information","ror":"https://ror.org/02meqm098","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I2800548410","https://openalex.org/I4210109390"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ben Busby","raw_affiliation_strings":["National Center for Biotechnology Information, National Library of Medicine, Bethesda, USA","National Center for Biotechnology Information, National Library of Medicine, Bethesda"],"raw_orcid":"https://orcid.org/0000-0001-5267-4988","affiliations":[{"raw_affiliation_string":"National Center for Biotechnology Information, National Library of Medicine, Bethesda, USA","institution_ids":["https://openalex.org/I4210109390"]},{"raw_affiliation_string":"National Center for Biotechnology Information, National Library of Medicine, Bethesda","institution_ids":["https://openalex.org/I4210109390"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5053458657"],"corresponding_institution_ids":["https://openalex.org/I4210109390"],"apc_list":{"value":1350,"currency":"USD","value_usd":1350},"apc_paid":{"value":1350,"currency":"USD","value_usd":1350},"fwci":0.3482,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":{"value":0.67990041,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"5","issue":null,"first_page":"674","last_page":"674"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9966999888420105,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pipeline","display_name":"Pipeline (software)","score":0.754357099533081},{"id":"https://openalex.org/keywords/network-analysis","display_name":"Network analysis","score":0.5307880640029907},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5286149382591248},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.4841664433479309},{"id":"https://openalex.org/keywords/code","display_name":"Code (set theory)","score":0.4652486741542816},{"id":"https://openalex.org/keywords/link","display_name":"Link (geometry)","score":0.4332888722419739},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.3843783140182495},{"id":"https://openalex.org/keywords/computer-network","display_name":"Computer network","score":0.2706899046897888},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.17372238636016846},{"id":"https://openalex.org/keywords/programming-language","display_name":"Programming language","score":0.16407501697540283}],"concepts":[{"id":"https://openalex.org/C43521106","wikidata":"https://www.wikidata.org/wiki/Q2165493","display_name":"Pipeline (software)","level":2,"score":0.754357099533081},{"id":"https://openalex.org/C32946077","wikidata":"https://www.wikidata.org/wiki/Q618079","display_name":"Network analysis","level":2,"score":0.5307880640029907},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5286149382591248},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4841664433479309},{"id":"https://openalex.org/C2776760102","wikidata":"https://www.wikidata.org/wiki/Q5139990","display_name":"Code (set theory)","level":3,"score":0.4652486741542816},{"id":"https://openalex.org/C2778753846","wikidata":"https://www.wikidata.org/wiki/Q6554239","display_name":"Link (geometry)","level":2,"score":0.4332888722419739},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3843783140182495},{"id":"https://openalex.org/C31258907","wikidata":"https://www.wikidata.org/wiki/Q1301371","display_name":"Computer network","level":1,"score":0.2706899046897888},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.17372238636016846},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.16407501697540283},{"id":"https://openalex.org/C119599485","wikidata":"https://www.wikidata.org/wiki/Q43035","display_name":"Electrical engineering","level":1,"score":0.0},{"id":"https://openalex.org/C177264268","wikidata":"https://www.wikidata.org/wiki/Q1514741","display_name":"Set (abstract data type)","level":2,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.12688/f1000research.8288.1","is_oa":true,"landing_page_url":"https://doi.org/10.12688/f1000research.8288.1","pdf_url":"https://f1000research.com/articles/5-674/v1/pdf","source":{"id":"https://openalex.org/S4210239046","display_name":"F1000Research","issn_l":"2046-1402","issn":["2046-1402"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320357","host_organization_name":"Faculty of 1000","host_organization_lineage":["https://openalex.org/P4310320357"],"host_organization_lineage_names":["Faculty of 1000"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"F1000Research","raw_type":"journal-article"},{"id":"pmid:27158457","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/27158457","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"F1000Research","raw_type":null},{"id":"pmh:oai:doaj.org/article:c295389977d94c82a0cfad4153685d55","is_oa":true,"landing_page_url":"https://doaj.org/article/c295389977d94c82a0cfad4153685d55","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"F1000Research, Vol 5 (2016)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4857755","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4857755","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"F1000Res","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.12688/f1000research.8288.1","is_oa":true,"landing_page_url":"https://doi.org/10.12688/f1000research.8288.1","pdf_url":"https://f1000research.com/articles/5-674/v1/pdf","source":{"id":"https://openalex.org/S4210239046","display_name":"F1000Research","issn_l":"2046-1402","issn":["2046-1402"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320357","host_organization_name":"Faculty of 1000","host_organization_lineage":["https://openalex.org/P4310320357"],"host_organization_lineage_names":["Faculty of 1000"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"F1000Research","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.4399999976158142,"display_name":"Partnerships for the goals","id":"https://metadata.un.org/sdg/17"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337372","display_name":"U.S. National Library of Medicine","ror":"https://ror.org/0060t0j89"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2337203490.pdf","grobid_xml":"https://content.openalex.org/works/W2337203490.grobid-xml"},"referenced_works_count":22,"referenced_works":["https://openalex.org/W1985213868","https://openalex.org/W1991832623","https://openalex.org/W2003283154","https://openalex.org/W2007203150","https://openalex.org/W2021135205","https://openalex.org/W2080310417","https://openalex.org/W2088544963","https://openalex.org/W2088891952","https://openalex.org/W2095319945","https://openalex.org/W2125984976","https://openalex.org/W2132450464","https://openalex.org/W2146653758","https://openalex.org/W2158705060","https://openalex.org/W2159482845","https://openalex.org/W2161633633","https://openalex.org/W2164298117","https://openalex.org/W2168511422","https://openalex.org/W2174602966","https://openalex.org/W2179127114","https://openalex.org/W2265889397","https://openalex.org/W2320983896","https://openalex.org/W2417986122"],"related_works":["https://openalex.org/W1518185400","https://openalex.org/W3200586296","https://openalex.org/W4230332972","https://openalex.org/W1998033311","https://openalex.org/W4247322236","https://openalex.org/W4231165741","https://openalex.org/W233457313","https://openalex.org/W4295104149","https://openalex.org/W1762272577","https://openalex.org/W4206960768"],"abstract_inverted_index":{"Network":[0],"analysis":[1,5],"can":[2,16],"make":[3],"variant":[4],"better.":[6],"There":[7],"are":[8],"existing":[9],"tools":[10],"like":[11],"HotNet2":[12],"and":[13],"dmGWAS":[14],"that":[15,30],"provide":[17],"various":[18],"analytical":[19],"methods.":[20],"We":[21],"developed":[22],"a":[23,26],"prototype":[24,44],"of":[25,33],"pipeline":[27],"called":[28],"MetaNetVar":[29],"allows":[31],"execution":[32],"multiple":[34],"tools.":[35],"The":[36],"code":[37],"is":[38,45],"published":[39,46],"at":[40],"https://github.com/NCBI-Hackathons/Network_SNPs.":[41],"A":[42],"working":[43],"as":[47],"an":[48],"Amazon":[49],"Machine":[50],"Image":[51],"-":[52],"ami-4510312f":[53],".":[54]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1}],"updated_date":"2026-05-06T08:25:59.206177","created_date":"2025-10-10T00:00:00"}