{"id":"https://openalex.org/W4414645709","doi":"https://doi.org/10.1186/s40708-025-00273-y","title":"Post-stroke brain functional reorganization is associated with glymphatic dysfunction during stroke recovery","display_name":"Post-stroke brain functional reorganization is associated with glymphatic dysfunction during stroke recovery","publication_year":2025,"publication_date":"2025-09-30","ids":{"openalex":"https://openalex.org/W4414645709","doi":"https://doi.org/10.1186/s40708-025-00273-y","pmid":"https://pubmed.ncbi.nlm.nih.gov/41028330"},"language":"en","primary_location":{"id":"doi:10.1186/s40708-025-00273-y","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s40708-025-00273-y","pdf_url":"https://braininformatics.springeropen.com/counter/pdf/10.1186/s40708-025-00273-y","source":{"id":"https://openalex.org/S2498492389","display_name":"Brain Informatics","issn_l":"2198-4018","issn":["2198-4018","2198-4026"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brain Informatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://braininformatics.springeropen.com/counter/pdf/10.1186/s40708-025-00273-y","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5102538897","display_name":"Yueyan Bian","orcid":null},"institutions":[{"id":"https://openalex.org/I1327237609","display_name":"Ministry of Education of the People's Republic of China","ror":"https://ror.org/01mv9t934","country_code":"CN","type":"government","lineage":["https://openalex.org/I1327237609","https://openalex.org/I4210127390"]},{"id":"https://openalex.org/I183519381","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60","country_code":"CN","type":"education","lineage":["https://openalex.org/I183519381"]},{"id":"https://openalex.org/I2800232565","display_name":"Beijing Chao-Yang Hospital, Capital Medical University","ror":"https://ror.org/01eff5662","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2800232565","https://openalex.org/I4210110145","https://openalex.org/I4210135108"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yueyan Bian","raw_affiliation_strings":["Department of Radiology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, 100020, China","Key Lab of Medical Engineering for Cardiovascular Disease, Ministry of Education, Beijing, 100020, China","Laboratory for Clinical Medicine, Capital Medical University, Beijing, 100020, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, 100020, China","institution_ids":["https://openalex.org/I183519381","https://openalex.org/I2800232565"]},{"raw_affiliation_string":"Key Lab of Medical Engineering for Cardiovascular Disease, Ministry of Education, Beijing, 100020, China","institution_ids":["https://openalex.org/I1327237609"]},{"raw_affiliation_string":"Laboratory for Clinical Medicine, Capital Medical University, Beijing, 100020, China","institution_ids":["https://openalex.org/I183519381"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101630606","display_name":"Jiajia Zhang","orcid":"https://orcid.org/0000-0003-1201-3987"},"institutions":[{"id":"https://openalex.org/I1327237609","display_name":"Ministry of Education of the People's Republic of China","ror":"https://ror.org/01mv9t934","country_code":"CN","type":"government","lineage":["https://openalex.org/I1327237609","https://openalex.org/I4210127390"]},{"id":"https://openalex.org/I183519381","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60","country_code":"CN","type":"education","lineage":["https://openalex.org/I183519381"]},{"id":"https://openalex.org/I2800232565","display_name":"Beijing Chao-Yang Hospital, Capital Medical University","ror":"https://ror.org/01eff5662","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2800232565","https://openalex.org/I4210110145","https://openalex.org/I4210135108"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jiajia Zhang","raw_affiliation_strings":["Department of Radiology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, 100020, China","Key Lab of Medical Engineering for Cardiovascular Disease, Ministry of Education, Beijing, 100020, China","Laboratory for Clinical Medicine, Capital Medical University, Beijing, 100020, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, 100020, China","institution_ids":["https://openalex.org/I183519381","https://openalex.org/I2800232565"]},{"raw_affiliation_string":"Key Lab of Medical Engineering for Cardiovascular Disease, Ministry of Education, Beijing, 100020, China","institution_ids":["https://openalex.org/I1327237609"]},{"raw_affiliation_string":"Laboratory for Clinical Medicine, Capital Medical University, Beijing, 100020, China","institution_ids":["https://openalex.org/I183519381"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100439350","display_name":"Yifei Zhang","orcid":"https://orcid.org/0000-0002-1344-5004"},"institutions":[{"id":"https://openalex.org/I189448455","display_name":"General Electric (Spain)","ror":"https://ror.org/04gbh9b75","country_code":"ES","type":"company","lineage":["https://openalex.org/I1332737386","https://openalex.org/I189448455"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Yifei Zhang","raw_affiliation_strings":["GE Healthcare MR Research, Beijing, 100176, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"GE Healthcare MR Research, Beijing, 100176, China","institution_ids":["https://openalex.org/I189448455"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100379715","display_name":"Hongxia Zhang","orcid":"https://orcid.org/0000-0002-3259-2755"},"institutions":[{"id":"https://openalex.org/I183519381","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60","country_code":"CN","type":"education","lineage":["https://openalex.org/I183519381"]},{"id":"https://openalex.org/I2800232565","display_name":"Beijing Chao-Yang Hospital, Capital Medical University","ror":"https://ror.org/01eff5662","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2800232565","https://openalex.org/I4210110145","https://openalex.org/I4210135108"]},{"id":"https://openalex.org/I2802459333","display_name":"China Rehabilitation Research Center","ror":"https://ror.org/02bpqmq41","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2802459333"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hongxia Zhang","raw_affiliation_strings":["Department of Radiology, Beijing Bo'ai Hospital, China Rehabilitation Research Center, Capital Medical University School of Rehabilitation Medicine, Beijing, 100068, China","Department of Radiology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, 100020, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Beijing Bo'ai Hospital, China Rehabilitation Research Center, Capital Medical University School of Rehabilitation Medicine, Beijing, 100068, China","institution_ids":["https://openalex.org/I2802459333"]},{"raw_affiliation_string":"Department of Radiology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, 100020, China","institution_ids":["https://openalex.org/I183519381","https://openalex.org/I2800232565"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084193032","display_name":"Xuejia Jia","orcid":"https://orcid.org/0000-0001-5515-2245"},"institutions":[{"id":"https://openalex.org/I1327237609","display_name":"Ministry of Education of the People's Republic of China","ror":"https://ror.org/01mv9t934","country_code":"CN","type":"government","lineage":["https://openalex.org/I1327237609","https://openalex.org/I4210127390"]},{"id":"https://openalex.org/I183519381","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60","country_code":"CN","type":"education","lineage":["https://openalex.org/I183519381"]},{"id":"https://openalex.org/I2800232565","display_name":"Beijing Chao-Yang Hospital, Capital Medical University","ror":"https://ror.org/01eff5662","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2800232565","https://openalex.org/I4210110145","https://openalex.org/I4210135108"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xuejia Jia","raw_affiliation_strings":["Department of Radiology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, 100020, China","Department of Radiology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, 100020, China. xqjia2014@163.com","Key Lab of Medical Engineering for Cardiovascular Disease, Ministry of Education, Beijing, 100020, China","Key Lab of Medical Engineering for Cardiovascular Disease, Ministry of Education, Beijing, 100020, China. xqjia2014@163.com","Laboratory for Clinical Medicine, Capital Medical University, Beijing, 100020, China","Medical Research Center, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, 100020, China. xqjia2014@163.com"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, 100020, China","institution_ids":["https://openalex.org/I183519381","https://openalex.org/I2800232565"]},{"raw_affiliation_string":"Department of Radiology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, 100020, China. xqjia2014@163.com","institution_ids":["https://openalex.org/I2800232565"]},{"raw_affiliation_string":"Key Lab of Medical Engineering for Cardiovascular Disease, Ministry of Education, Beijing, 100020, China","institution_ids":["https://openalex.org/I1327237609"]},{"raw_affiliation_string":"Key Lab of Medical Engineering for Cardiovascular Disease, Ministry of Education, Beijing, 100020, China. xqjia2014@163.com","institution_ids":["https://openalex.org/I1327237609"]},{"raw_affiliation_string":"Laboratory for Clinical Medicine, Capital Medical University, Beijing, 100020, China","institution_ids":["https://openalex.org/I183519381"]},{"raw_affiliation_string":"Medical Research Center, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, 100020, China. xqjia2014@163.com","institution_ids":["https://openalex.org/I2800232565"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010996024","display_name":"Hongkai Wang","orcid":"https://orcid.org/0000-0002-1813-2162"},"institutions":[{"id":"https://openalex.org/I27357992","display_name":"Dalian University of Technology","ror":"https://ror.org/023hj5876","country_code":"CN","type":"education","lineage":["https://openalex.org/I27357992"]},{"id":"https://openalex.org/I4210092944","display_name":"Dalian University","ror":"https://ror.org/00g2ypp58","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210092944"]},{"id":"https://openalex.org/I4210124847","display_name":"National Engineering Research Center of Electromagnetic Radiation Control Materials","ror":"https://ror.org/02k4dcs46","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210124847"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hongkai Wang","raw_affiliation_strings":["Liaoning Key Laboratory of Integrated Circuit and Biomedical Electronic System, Dalian, 116024, China","School of Bioengineering, Dalian University of Technology, Dalian, 116024, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Liaoning Key Laboratory of Integrated Circuit and Biomedical Electronic System, Dalian, 116024, China","institution_ids":["https://openalex.org/I4210124847"]},{"raw_affiliation_string":"School of Bioengineering, Dalian University of Technology, Dalian, 116024, China","institution_ids":["https://openalex.org/I27357992","https://openalex.org/I4210092944"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061211243","display_name":"Xiuqin Jia","orcid":null},"institutions":[{"id":"https://openalex.org/I1327237609","display_name":"Ministry of Education of the People's Republic of China","ror":"https://ror.org/01mv9t934","country_code":"CN","type":"government","lineage":["https://openalex.org/I1327237609","https://openalex.org/I4210127390"]},{"id":"https://openalex.org/I183519381","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60","country_code":"CN","type":"education","lineage":["https://openalex.org/I183519381"]},{"id":"https://openalex.org/I2800232565","display_name":"Beijing Chao-Yang Hospital, Capital Medical University","ror":"https://ror.org/01eff5662","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2800232565","https://openalex.org/I4210110145","https://openalex.org/I4210135108"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Xiuqin Jia","raw_affiliation_strings":["Department of Radiology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, 100020, China","Department of Radiology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, 100020, China. xqjia2014@163.com","Key Lab of Medical Engineering for Cardiovascular Disease, Ministry of Education, Beijing, 100020, China","Key Lab of Medical Engineering for Cardiovascular Disease, Ministry of Education, Beijing, 100020, China. xqjia2014@163.com","Laboratory for Clinical Medicine, Capital Medical University, Beijing, 100020, China","Medical Research Center, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, 100020, China. xqjia2014@163.com","Medical Research Center, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, 100020, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, 100020, China","institution_ids":["https://openalex.org/I183519381","https://openalex.org/I2800232565"]},{"raw_affiliation_string":"Department of Radiology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, 100020, China. xqjia2014@163.com","institution_ids":["https://openalex.org/I2800232565"]},{"raw_affiliation_string":"Key Lab of Medical Engineering for Cardiovascular Disease, Ministry of Education, Beijing, 100020, China","institution_ids":["https://openalex.org/I1327237609"]},{"raw_affiliation_string":"Key Lab of Medical Engineering for Cardiovascular Disease, Ministry of Education, Beijing, 100020, China. xqjia2014@163.com","institution_ids":["https://openalex.org/I1327237609"]},{"raw_affiliation_string":"Laboratory for Clinical Medicine, Capital Medical University, Beijing, 100020, China","institution_ids":["https://openalex.org/I183519381"]},{"raw_affiliation_string":"Medical Research Center, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, 100020, China. xqjia2014@163.com","institution_ids":["https://openalex.org/I2800232565"]},{"raw_affiliation_string":"Medical Research Center, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, 100020, China","institution_ids":["https://openalex.org/I183519381","https://openalex.org/I2800232565"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101728748","display_name":"Qi Yang","orcid":"https://orcid.org/0000-0002-2963-7983"},"institutions":[{"id":"https://openalex.org/I1327237609","display_name":"Ministry of Education of the People's Republic of China","ror":"https://ror.org/01mv9t934","country_code":"CN","type":"government","lineage":["https://openalex.org/I1327237609","https://openalex.org/I4210127390"]},{"id":"https://openalex.org/I183519381","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60","country_code":"CN","type":"education","lineage":["https://openalex.org/I183519381"]},{"id":"https://openalex.org/I2800232565","display_name":"Beijing Chao-Yang Hospital, Capital Medical University","ror":"https://ror.org/01eff5662","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2800232565","https://openalex.org/I4210110145","https://openalex.org/I4210135108"]},{"id":"https://openalex.org/I4210094876","display_name":"Ministry of Education","ror":"https://ror.org/00q919b81","country_code":"SA","type":"government","lineage":["https://openalex.org/I4210094876"]}],"countries":["CN","SA"],"is_corresponding":false,"raw_author_name":"Qi Yang","raw_affiliation_strings":["Department of Radiology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, 100020, China. yangyangqiqi@gmail.com","Key Lab of Medical Engineering for Cardiovascular Disease, Ministry of Education, Beijing, 100020, China. yangyangqiqi@gmail.com","Laboratory for Clinical Medicine, Capital Medical University, Beijing, 100020, China. yangyangqiqi@gmail.com","Department of Radiology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, 100020, China","Key Lab of Medical Engineering for Cardiovascular Disease, Ministry of Education, Beijing, 100020, China","Laboratory for Clinical Medicine, Capital Medical University, Beijing, 100020, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, 100020, China. yangyangqiqi@gmail.com","institution_ids":["https://openalex.org/I2800232565"]},{"raw_affiliation_string":"Key Lab of Medical Engineering for Cardiovascular Disease, Ministry of Education, Beijing, 100020, China. yangyangqiqi@gmail.com","institution_ids":["https://openalex.org/I4210094876"]},{"raw_affiliation_string":"Laboratory for Clinical Medicine, Capital Medical University, Beijing, 100020, China. yangyangqiqi@gmail.com","institution_ids":["https://openalex.org/I183519381"]},{"raw_affiliation_string":"Department of Radiology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, 100020, China","institution_ids":["https://openalex.org/I183519381","https://openalex.org/I2800232565"]},{"raw_affiliation_string":"Key Lab of Medical Engineering for Cardiovascular Disease, Ministry of Education, Beijing, 100020, China","institution_ids":["https://openalex.org/I1327237609"]},{"raw_affiliation_string":"Laboratory for Clinical Medicine, Capital Medical University, Beijing, 100020, China","institution_ids":["https://openalex.org/I183519381"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5061211243"],"corresponding_institution_ids":["https://openalex.org/I1327237609","https://openalex.org/I183519381","https://openalex.org/I2800232565"],"apc_list":{"value":990,"currency":"USD","value_usd":990},"apc_paid":{"value":990,"currency":"USD","value_usd":990},"fwci":2.4655,"has_fulltext":true,"cited_by_count":5,"citation_normalized_percentile":{"value":0.90069735,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":91,"max":99},"biblio":{"volume":"12","issue":"1","first_page":"24","last_page":"24"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11406","display_name":"Cerebrospinal fluid and hydrocephalus","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11406","display_name":"Cerebrospinal fluid and hydrocephalus","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11304","display_name":"Advanced Neuroimaging Techniques and Applications","score":0.9983000159263611,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11833","display_name":"Spinal Dysraphism and Malformations","score":0.9977999925613403,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/glymphatic-system","display_name":"Glymphatic system","score":0.7645000219345093},{"id":"https://openalex.org/keywords/putamen","display_name":"Putamen","score":0.597599983215332},{"id":"https://openalex.org/keywords/diffusion-mri","display_name":"Diffusion MRI","score":0.5781000256538391},{"id":"https://openalex.org/keywords/stroke","display_name":"Stroke (engine)","score":0.5515999794006348},{"id":"https://openalex.org/keywords/stroke-recovery","display_name":"Stroke recovery","score":0.4025000035762787},{"id":"https://openalex.org/keywords/magnetic-resonance-imaging","display_name":"Magnetic resonance imaging","score":0.3686000108718872},{"id":"https://openalex.org/keywords/thalamus","display_name":"Thalamus","score":0.36820000410079956}],"concepts":[{"id":"https://openalex.org/C101054994","wikidata":"https://www.wikidata.org/wiki/Q15474254","display_name":"Glymphatic system","level":3,"score":0.7645000219345093},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6575999855995178},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.6100000143051147},{"id":"https://openalex.org/C2779714222","wikidata":"https://www.wikidata.org/wiki/Q550934","display_name":"Putamen","level":2,"score":0.597599983215332},{"id":"https://openalex.org/C149550507","wikidata":"https://www.wikidata.org/wiki/Q899360","display_name":"Diffusion MRI","level":3,"score":0.5781000256538391},{"id":"https://openalex.org/C2780645631","wikidata":"https://www.wikidata.org/wiki/Q671554","display_name":"Stroke (engine)","level":2,"score":0.5515999794006348},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.49639999866485596},{"id":"https://openalex.org/C2776361831","wikidata":"https://www.wikidata.org/wiki/Q10681911","display_name":"Stroke recovery","level":3,"score":0.4025000035762787},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.3686000108718872},{"id":"https://openalex.org/C2779246727","wikidata":"https://www.wikidata.org/wiki/Q184215","display_name":"Thalamus","level":2,"score":0.36820000410079956},{"id":"https://openalex.org/C2779226451","wikidata":"https://www.wikidata.org/wiki/Q903809","display_name":"Functional magnetic resonance imaging","level":2,"score":0.31619998812675476},{"id":"https://openalex.org/C50231774","wikidata":"https://www.wikidata.org/wiki/Q639842","display_name":"Brain mapping","level":2,"score":0.3125999867916107},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.31130000948905945},{"id":"https://openalex.org/C182752723","wikidata":"https://www.wikidata.org/wiki/Q1474590","display_name":"Functional imaging","level":2,"score":0.3059000074863434},{"id":"https://openalex.org/C2779281540","wikidata":"https://www.wikidata.org/wiki/Q5062122","display_name":"Central nervous system disease","level":2,"score":0.2786000072956085},{"id":"https://openalex.org/C3020199598","wikidata":"https://www.wikidata.org/wiki/Q12202","display_name":"Ischemic stroke","level":3,"score":0.2703000009059906},{"id":"https://openalex.org/C30036603","wikidata":"https://www.wikidata.org/wiki/Q17125150","display_name":"Severity of illness","level":2,"score":0.2632000148296356},{"id":"https://openalex.org/C157767197","wikidata":"https://www.wikidata.org/wiki/Q886843","display_name":"Cerebral blood flow","level":2,"score":0.25699999928474426},{"id":"https://openalex.org/C58693492","wikidata":"https://www.wikidata.org/wiki/Q551875","display_name":"Neuroimaging","level":2,"score":0.2549000084400177},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.2538999915122986}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.1186/s40708-025-00273-y","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s40708-025-00273-y","pdf_url":"https://braininformatics.springeropen.com/counter/pdf/10.1186/s40708-025-00273-y","source":{"id":"https://openalex.org/S2498492389","display_name":"Brain Informatics","issn_l":"2198-4018","issn":["2198-4018","2198-4026"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brain Informatics","raw_type":"journal-article"},{"id":"pmid:41028330","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41028330","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brain informatics","raw_type":null},{"id":"pmh:oai:doaj.org/article:e9b4d9887de8482db4793c703b6188c0","is_oa":true,"landing_page_url":"https://doaj.org/article/e9b4d9887de8482db4793c703b6188c0","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Brain Informatics, Vol 12, Iss 1, Pp 1-14 (2025)","raw_type":"article"},{"id":"pmh:oai:europepmc.org:11296300","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12484500","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:12484500","is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12484500/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Brain Inform","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/s40708-025-00273-y","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s40708-025-00273-y","pdf_url":"https://braininformatics.springeropen.com/counter/pdf/10.1186/s40708-025-00273-y","source":{"id":"https://openalex.org/S2498492389","display_name":"Brain Informatics","issn_l":"2198-4018","issn":["2198-4018","2198-4026"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brain Informatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G2153846675","display_name":null,"funder_award_id":"L252089","funder_id":"https://openalex.org/F4320334977","funder_display_name":"Beijing Municipal Natural Science Foundation"},{"id":"https://openalex.org/G6409621128","display_name":null,"funder_award_id":"U24A20753","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G8066197752","display_name":null,"funder_award_id":"82025018","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320321496","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60"},{"id":"https://openalex.org/F4320334977","display_name":"Beijing Municipal Natural Science Foundation","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4414645709.pdf","grobid_xml":"https://content.openalex.org/works/W4414645709.grobid-xml"},"referenced_works_count":44,"referenced_works":["https://openalex.org/W1980927563","https://openalex.org/W1983352521","https://openalex.org/W2028623620","https://openalex.org/W2040868194","https://openalex.org/W2056306065","https://openalex.org/W2071666535","https://openalex.org/W2145991132","https://openalex.org/W2169755717","https://openalex.org/W2460096162","https://openalex.org/W2518447784","https://openalex.org/W2553831596","https://openalex.org/W2559793610","https://openalex.org/W2587835995","https://openalex.org/W2588487507","https://openalex.org/W2606975747","https://openalex.org/W2895939677","https://openalex.org/W2916055237","https://openalex.org/W2993316870","https://openalex.org/W3004007615","https://openalex.org/W3134338907","https://openalex.org/W3134493171","https://openalex.org/W3154061441","https://openalex.org/W3160045421","https://openalex.org/W3166279289","https://openalex.org/W3170975817","https://openalex.org/W3184431040","https://openalex.org/W3188643330","https://openalex.org/W3203081744","https://openalex.org/W3214040964","https://openalex.org/W4200238923","https://openalex.org/W4220718010","https://openalex.org/W4280572794","https://openalex.org/W4311616532","https://openalex.org/W4312128833","https://openalex.org/W4362519173","https://openalex.org/W4379508166","https://openalex.org/W4385298898","https://openalex.org/W4387078315","https://openalex.org/W4391023451","https://openalex.org/W4399430385","https://openalex.org/W4405728553","https://openalex.org/W4408533210","https://openalex.org/W4410220008","https://openalex.org/W4411368998"],"related_works":[],"abstract_inverted_index":{"BACKGROUND:":[0],"Ischemic":[1],"stroke":[2,27,32],"may":[3,297],"impair":[4],"glymphatic":[5,74,111,133,280,294],"clearance,":[6],"but":[7],"whether":[8],"this":[9],"is":[10],"associated":[11,109,249,262,277],"with":[12,77,110,177,211,250,263,278],"post-stroke":[13,279,293,303],"brain":[14],"functional":[15,71,89,106,130],"reorganization":[16,72,107,131,144,270],"in":[17,113,158,163,235,242,255,271,282],"humans":[18],"remains":[19],"unclear.":[20],"METHODS:":[21],"We":[22],"prospectively":[23],"enrolled":[24],"48":[25],"capsular":[26],"(CS)":[28],"patients,":[29,34,171,201,244,257],"28":[30],"pontine":[31],"(PS)":[33],"and":[35,49,56,73,95,115,132,138,145,153,161,180,214,274,296],"50":[36],"healthy":[37],"controls.":[38],"All":[39],"participants":[40],"underwent":[41],"MRI":[42],"examinations":[43],"at":[44],"baseline":[45,172,179,202,213],"(<":[46],"7":[47],"days)":[48],"90":[50],"days":[51],"post-stroke.":[52],"Cerebrovascular":[53],"reactivity":[54],"(CVR)":[55],"the":[57,62,126,159,167,236,272],"diffusion":[58],"tensor":[59],"imaging":[60],"along":[61],"perivascular":[63],"space":[64],"(DTI-ALPS)":[65],"index":[66],"were":[67,82,98,108,122,156,233,247,260],"measured":[68],"to":[69,100,105,124,301],"assess":[70],"function.":[75],"Regions":[76],"significant":[78],"intergroup":[79],"CVR":[80,94,143,152,173,216,245,265,269],"differences":[81],"identified":[83],"as":[84],"regions-of-interest":[85],"(ROIs)":[86],"reflecting":[87],"focal":[88,142],"reorganization.":[90],"Correlations":[91],"between":[92,151],"ROI-based":[93],"DTI-ALPS":[96,147,154,184,205,259],"indices":[97,155,185,206],"analyzed":[99],"determine":[101],"which":[102],"ROIs":[103],"related":[104],"function":[112],"CS":[114,137,170,243],"PS":[116,139,200,256],"patients.":[117],"Cross-lagged":[118],"panel":[119],"models":[120],"(CLPMs)":[121],"constructed":[123],"analyze":[125],"temporal":[127],"sequence":[128],"of":[129,231,292],"dysfunction.":[134],"RESULTS:":[135],"Both":[136],"patients":[140],"exhibited":[141],"reduced":[146,252,258],"indices.":[148],"Significant":[149],"associations":[150],"found":[157],"putamen":[160,273],"thalamus":[162,275],"both":[164,178,212],"groups.":[165],"In":[166,199],"putamen,":[168],"among":[169],"was":[174,208,276],"negatively":[175,209],"correlated":[176,210],"90-day":[181,215],"ipsilesional":[182],"hemispheric":[183,204],"(IL.DTI-ALPS)":[186],"(r":[187,217],"=":[188,191,194,218,221,224,227],"-0.479,":[189],"p":[190,196,220,226],"0.001;":[192],"r":[193,223],"-0.493,":[195],"<":[197],"0.001).":[198],"contralesional":[203],"(CL.DTI-ALPS)":[207],"-0.510,":[219],"0.006;":[222],"-0.532,":[225],"0.004).":[228],"Similar":[229],"patterns":[230],"association":[232],"observed":[234],"thalamus.":[237],"Additionally,":[238],"CLPMs":[239],"revealed":[240],"that":[241],"changes":[246],"temporally":[248,261],"subsequently":[251],"DTI-ALPS,":[253],"while":[254],"subsequent":[264],"changes.":[266],"CONCLUSIONS:":[267],"Focal":[268],"dysfunction":[281],"a":[283],"bidirectional,":[284],"lesion-location-specific":[285],"manner.":[286],"These":[287],"findings":[288],"enhance":[289],"our":[290],"understanding":[291],"impairment":[295],"help":[298],"inform":[299],"strategies":[300],"mitigate":[302],"cognitive":[304],"decline.":[305]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":1}],"updated_date":"2026-07-23T08:03:31.855105","created_date":"2025-10-10T00:00:00"}