{"id":"https://openalex.org/W4402495302","doi":"https://doi.org/10.1186/s40537-024-00997-4","title":"Leveraging large-scale genetic data to assess the causal impact of COVID-19 on multisystemic diseases","display_name":"Leveraging large-scale genetic data to assess the causal impact of COVID-19 on multisystemic diseases","publication_year":2024,"publication_date":"2024-09-12","ids":{"openalex":"https://openalex.org/W4402495302","doi":"https://doi.org/10.1186/s40537-024-00997-4"},"language":"en","primary_location":{"id":"doi:10.1186/s40537-024-00997-4","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1186/s40537-024-00997-4","pdf_url":"https://link.springer.com/content/pdf/10.1186/s40537-024-00997-4.pdf","source":{"id":"https://openalex.org/S2737955091","display_name":"Journal Of Big Data","issn_l":"2196-1115","issn":["2196-1115"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Big Data","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://link.springer.com/content/pdf/10.1186/s40537-024-00997-4.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100344782","display_name":"Xiangyang Zhang","orcid":"https://orcid.org/0009-0009-5015-9478"},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]},{"id":"https://openalex.org/I4210159865","display_name":"Xiangya Hospital Central South University","ror":"https://ror.org/05c1yfj14","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210159865"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Xiangyang Zhang","raw_affiliation_strings":["Department of Oncology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China"],"affiliations":[{"raw_affiliation_string":"Department of Oncology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China","institution_ids":["https://openalex.org/I4210159865","https://openalex.org/I139660479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013235835","display_name":"Zhaohui Jiang","orcid":"https://orcid.org/0000-0002-4861-5819"},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]},{"id":"https://openalex.org/I4210159865","display_name":"Xiangya Hospital Central South University","ror":"https://ror.org/05c1yfj14","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210159865"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhaohui Jiang","raw_affiliation_strings":["Department of Oncology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China"],"affiliations":[{"raw_affiliation_string":"Department of Oncology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China","institution_ids":["https://openalex.org/I4210159865","https://openalex.org/I139660479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100324760","display_name":"Jiayao Ma","orcid":"https://orcid.org/0000-0002-6146-9940"},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]},{"id":"https://openalex.org/I4210159865","display_name":"Xiangya Hospital Central South University","ror":"https://ror.org/05c1yfj14","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210159865"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jiayao Ma","raw_affiliation_strings":["Department of Oncology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China"],"affiliations":[{"raw_affiliation_string":"Department of Oncology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China","institution_ids":["https://openalex.org/I4210159865","https://openalex.org/I139660479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054145774","display_name":"Yaru Qi","orcid":null},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]},{"id":"https://openalex.org/I4210159865","display_name":"Xiangya Hospital Central South University","ror":"https://ror.org/05c1yfj14","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210159865"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yaru Qi","raw_affiliation_strings":["Department of Oncology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China"],"affiliations":[{"raw_affiliation_string":"Department of Oncology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China","institution_ids":["https://openalex.org/I4210159865","https://openalex.org/I139660479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100451107","display_name":"Yin Li","orcid":"https://orcid.org/0000-0001-8610-6970"},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]},{"id":"https://openalex.org/I4210159865","display_name":"Xiangya Hospital Central South University","ror":"https://ror.org/05c1yfj14","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210159865"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yin Li","raw_affiliation_strings":["Department of Oncology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China"],"affiliations":[{"raw_affiliation_string":"Department of Oncology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China","institution_ids":["https://openalex.org/I4210159865","https://openalex.org/I139660479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100456286","display_name":"Yan Zhang","orcid":"https://orcid.org/0000-0002-6682-9917"},"institutions":[{"id":"https://openalex.org/I4210130275","display_name":"Yueyang Second People's Hospital","ror":"https://ror.org/03gh4m991","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210130275"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yan Zhang","raw_affiliation_strings":["Department of Oncology, Yueyang People\u2019s Hospital, Yueyang Hospital Affiliated to Hunan Normal University, Yueyang, 414022, Hunan, China"],"affiliations":[{"raw_affiliation_string":"Department of Oncology, Yueyang People\u2019s Hospital, Yueyang Hospital Affiliated to Hunan Normal University, Yueyang, 414022, Hunan, China","institution_ids":["https://openalex.org/I4210130275"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101861810","display_name":"Yihan Liu","orcid":"https://orcid.org/0000-0001-9094-0693"},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]},{"id":"https://openalex.org/I4210159865","display_name":"Xiangya Hospital Central South University","ror":"https://ror.org/05c1yfj14","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210159865"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yihan Liu","raw_affiliation_strings":["Department of Oncology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China"],"affiliations":[{"raw_affiliation_string":"Department of Oncology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China","institution_ids":["https://openalex.org/I4210159865","https://openalex.org/I139660479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027762398","display_name":"Chaochao Wei","orcid":null},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]},{"id":"https://openalex.org/I4210159865","display_name":"Xiangya Hospital Central South University","ror":"https://ror.org/05c1yfj14","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210159865"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chaochao Wei","raw_affiliation_strings":["Department of Oncology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China"],"affiliations":[{"raw_affiliation_string":"Department of Oncology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China","institution_ids":["https://openalex.org/I4210159865","https://openalex.org/I139660479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100615550","display_name":"Yihong Chen","orcid":"https://orcid.org/0000-0002-7037-2227"},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]},{"id":"https://openalex.org/I4210159865","display_name":"Xiangya Hospital Central South University","ror":"https://ror.org/05c1yfj14","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210159865"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yihong Chen","raw_affiliation_strings":["Department of Oncology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China"],"affiliations":[{"raw_affiliation_string":"Department of Oncology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China","institution_ids":["https://openalex.org/I4210159865","https://openalex.org/I139660479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5115588357","display_name":"Ping Liu","orcid":"https://orcid.org/0009-0008-2025-9331"},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]},{"id":"https://openalex.org/I4210159865","display_name":"Xiangya Hospital Central South University","ror":"https://ror.org/05c1yfj14","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210159865"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ping Liu","raw_affiliation_strings":["Department of Oncology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China"],"affiliations":[{"raw_affiliation_string":"Department of Oncology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China","institution_ids":["https://openalex.org/I4210159865","https://openalex.org/I139660479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102870327","display_name":"Yinghui Peng","orcid":"https://orcid.org/0000-0002-3676-3574"},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]},{"id":"https://openalex.org/I4210159865","display_name":"Xiangya Hospital Central South University","ror":"https://ror.org/05c1yfj14","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210159865"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yinghui Peng","raw_affiliation_strings":["Department of Oncology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China"],"affiliations":[{"raw_affiliation_string":"Department of Oncology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China","institution_ids":["https://openalex.org/I4210159865","https://openalex.org/I139660479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101480247","display_name":"Jun Tan","orcid":"https://orcid.org/0000-0001-9351-8340"},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]},{"id":"https://openalex.org/I4210159865","display_name":"Xiangya Hospital Central South University","ror":"https://ror.org/05c1yfj14","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210159865"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jun Tan","raw_affiliation_strings":["Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha, 410008, China"],"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha, 410008, China","institution_ids":["https://openalex.org/I4210159865","https://openalex.org/I139660479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007927256","display_name":"Ying Han","orcid":"https://orcid.org/0000-0001-8591-7894"},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]},{"id":"https://openalex.org/I4210159865","display_name":"Xiangya Hospital Central South University","ror":"https://ror.org/05c1yfj14","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210159865"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ying Han","raw_affiliation_strings":["Department of Oncology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China"],"affiliations":[{"raw_affiliation_string":"Department of Oncology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China","institution_ids":["https://openalex.org/I4210159865","https://openalex.org/I139660479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087809584","display_name":"Shan Zeng","orcid":"https://orcid.org/0000-0002-0988-723X"},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]},{"id":"https://openalex.org/I4210159865","display_name":"Xiangya Hospital Central South University","ror":"https://ror.org/05c1yfj14","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210159865"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shan Zeng","raw_affiliation_strings":["Department of Oncology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China"],"affiliations":[{"raw_affiliation_string":"Department of Oncology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China","institution_ids":["https://openalex.org/I4210159865","https://openalex.org/I139660479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036683671","display_name":"Changjing Cai","orcid":"https://orcid.org/0000-0002-9567-5582"},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]},{"id":"https://openalex.org/I4210159865","display_name":"Xiangya Hospital Central South University","ror":"https://ror.org/05c1yfj14","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210159865"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Changjing Cai","raw_affiliation_strings":["Department of Oncology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China"],"affiliations":[{"raw_affiliation_string":"Department of Oncology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China","institution_ids":["https://openalex.org/I4210159865","https://openalex.org/I139660479"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5074755903","display_name":"Hong Shen","orcid":"https://orcid.org/0000-0001-5345-4709"},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]},{"id":"https://openalex.org/I4210159865","display_name":"Xiangya Hospital Central South University","ror":"https://ror.org/05c1yfj14","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210159865"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hong Shen","raw_affiliation_strings":["Department of Oncology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China","National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, 410008, China"],"affiliations":[{"raw_affiliation_string":"Department of Oncology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China","institution_ids":["https://openalex.org/I4210159865","https://openalex.org/I139660479"]},{"raw_affiliation_string":"National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, 410008, China","institution_ids":["https://openalex.org/I4210159865","https://openalex.org/I139660479"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":16,"corresponding_author_ids":["https://openalex.org/A5100344782"],"corresponding_institution_ids":["https://openalex.org/I139660479","https://openalex.org/I4210159865"],"apc_list":{"value":1060,"currency":"GBP","value_usd":1300},"apc_paid":{"value":1060,"currency":"GBP","value_usd":1300},"fwci":0.5337,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.7364637,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":95},"biblio":{"volume":"11","issue":"1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.9983999729156494,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.9983999729156494,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10351","display_name":"Liver Disease Diagnosis and Treatment","score":0.9944000244140625,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10118","display_name":"SARS-CoV-2 and COVID-19 Research","score":0.9918000102043152,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/coronavirus-disease-2019","display_name":"Coronavirus disease 2019 (COVID-19)","score":0.7909889221191406},{"id":"https://openalex.org/keywords/2019-20-coronavirus-outbreak","display_name":"2019-20 coronavirus outbreak","score":0.6467654705047607},{"id":"https://openalex.org/keywords/scale","display_name":"Scale (ratio)","score":0.5960332155227661},{"id":"https://openalex.org/keywords/severe-acute-respiratory-syndrome-coronavirus-2","display_name":"Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)","score":0.5761875510215759},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5748602747917175},{"id":"https://openalex.org/keywords/computational-science-and-engineering","display_name":"Computational Science and Engineering","score":0.5291705131530762},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.49254927039146423},{"id":"https://openalex.org/keywords/virology","display_name":"Virology","score":0.2482781708240509},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.16101157665252686},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.14911901950836182},{"id":"https://openalex.org/keywords/geography","display_name":"Geography","score":0.07276427745819092},{"id":"https://openalex.org/keywords/cartography","display_name":"Cartography","score":0.07156616449356079}],"concepts":[{"id":"https://openalex.org/C3008058167","wikidata":"https://www.wikidata.org/wiki/Q84263196","display_name":"Coronavirus disease 2019 (COVID-19)","level":4,"score":0.7909889221191406},{"id":"https://openalex.org/C3006700255","wikidata":"https://www.wikidata.org/wiki/Q81068910","display_name":"2019-20 coronavirus outbreak","level":3,"score":0.6467654705047607},{"id":"https://openalex.org/C2778755073","wikidata":"https://www.wikidata.org/wiki/Q10858537","display_name":"Scale (ratio)","level":2,"score":0.5960332155227661},{"id":"https://openalex.org/C3007834351","wikidata":"https://www.wikidata.org/wiki/Q82069695","display_name":"Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)","level":5,"score":0.5761875510215759},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5748602747917175},{"id":"https://openalex.org/C68597687","wikidata":"https://www.wikidata.org/wiki/Q362601","display_name":"Computational Science and Engineering","level":2,"score":0.5291705131530762},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.49254927039146423},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.2482781708240509},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.16101157665252686},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.14911901950836182},{"id":"https://openalex.org/C205649164","wikidata":"https://www.wikidata.org/wiki/Q1071","display_name":"Geography","level":0,"score":0.07276427745819092},{"id":"https://openalex.org/C58640448","wikidata":"https://www.wikidata.org/wiki/Q42515","display_name":"Cartography","level":1,"score":0.07156616449356079},{"id":"https://openalex.org/C524204448","wikidata":"https://www.wikidata.org/wiki/Q788926","display_name":"Infectious disease (medical specialty)","level":3,"score":0.0},{"id":"https://openalex.org/C116675565","wikidata":"https://www.wikidata.org/wiki/Q3241045","display_name":"Outbreak","level":2,"score":0.0},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1186/s40537-024-00997-4","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1186/s40537-024-00997-4","pdf_url":"https://link.springer.com/content/pdf/10.1186/s40537-024-00997-4.pdf","source":{"id":"https://openalex.org/S2737955091","display_name":"Journal Of Big Data","issn_l":"2196-1115","issn":["2196-1115"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Big Data","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:37c358585b4f48ae81803b52f33be2c5","is_oa":true,"landing_page_url":"https://doaj.org/article/37c358585b4f48ae81803b52f33be2c5","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Big Data, Vol 11, Iss 1, Pp 1-18 (2024)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/s40537-024-00997-4","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1186/s40537-024-00997-4","pdf_url":"https://link.springer.com/content/pdf/10.1186/s40537-024-00997-4.pdf","source":{"id":"https://openalex.org/S2737955091","display_name":"Journal Of Big Data","issn_l":"2196-1115","issn":["2196-1115"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Big Data","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Zero hunger","score":0.4399999976158142,"id":"https://metadata.un.org/sdg/2"}],"awards":[{"id":"https://openalex.org/G1121271761","display_name":null,"funder_award_id":"Program","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G1212128389","display_name":null,"funder_award_id":"2021JJ3109, 2021JJ31048, 2023JJ40942 and 2024JJ6662","funder_id":"https://openalex.org/F4320322866","funder_display_name":"Natural Science Foundation of Hainan Province"},{"id":"https://openalex.org/G1231421488","display_name":null,"funder_award_id":"under","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G1790255562","display_name":null,"funder_award_id":"82373275, 81974384, 82173342 & 82203015","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G1977740159","display_name":null,"funder_award_id":"82403920","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G2082826544","display_name":null,"funder_award_id":"Postdoctoral","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G2171166193","display_name":null,"funder_award_id":"81974384","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G2376276132","display_name":null,"funder_award_id":"China","funder_id":"https://openalex.org/F4320335787","funder_display_name":"Fundamental Research Funds for the Central Universities"},{"id":"https://openalex.org/G2933548003","display_name":null,"funder_award_id":"2024M753679","funder_id":"https://openalex.org/F4320321543","funder_display_name":"China Postdoctoral Science Foundation"},{"id":"https://openalex.org/G3317480652","display_name":null,"funder_award_id":"Science","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G391238517","display_name":null,"funder_award_id":", and","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G4496145979","display_name":null,"funder_award_id":"2023JJ40942","funder_id":"https://openalex.org/F4320321543","funder_display_name":"China Postdoctoral Science Foundation"},{"id":"https://openalex.org/G5217273760","display_name":null,"funder_award_id":"62031023","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5700981909","display_name":null,"funder_award_id":"2050205","funder_id":"https://openalex.org/F4320335787","funder_display_name":"Fundamental Research Funds for the Central Universities"},{"id":"https://openalex.org/G5994120800","display_name":null,"funder_award_id":"Natural","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6256444366","display_name":null,"funder_award_id":"COVID-19","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6463213449","display_name":null,"funder_award_id":"2050205","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7212968922","display_name":null,"funder_award_id":"81874073","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7718612627","display_name":null,"funder_award_id":"82173342","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320321514","display_name":"Central South University","ror":"https://ror.org/00f1zfq44"},{"id":"https://openalex.org/F4320321543","display_name":"China Postdoctoral Science Foundation","ror":"https://ror.org/0426zh255"},{"id":"https://openalex.org/F4320322866","display_name":"Natural Science Foundation of Hainan Province","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320335740","display_name":"Xiangya Hospital, Central South University","ror":"https://ror.org/05akvb491"},{"id":"https://openalex.org/F4320335787","display_name":"Fundamental Research Funds for the Central Universities","ror":null},{"id":"https://openalex.org/F4320335880","display_name":"Fundamental Research Funds for Central Universities of the Central South University","ror":null}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4402495302.pdf","grobid_xml":"https://content.openalex.org/works/W4402495302.grobid-xml"},"referenced_works_count":65,"referenced_works":["https://openalex.org/W1902575419","https://openalex.org/W1905058580","https://openalex.org/W2082704080","https://openalex.org/W2103783427","https://openalex.org/W2113699335","https://openalex.org/W2128736149","https://openalex.org/W2143625465","https://openalex.org/W2166082348","https://openalex.org/W2324862792","https://openalex.org/W2334225836","https://openalex.org/W2488281607","https://openalex.org/W2601822003","https://openalex.org/W2613603864","https://openalex.org/W2768032009","https://openalex.org/W2770598799","https://openalex.org/W2802815532","https://openalex.org/W2803072880","https://openalex.org/W2805983714","https://openalex.org/W2943085208","https://openalex.org/W2947278243","https://openalex.org/W2953121869","https://openalex.org/W2953389908","https://openalex.org/W3001510487","https://openalex.org/W3011048540","https://openalex.org/W3011134208","https://openalex.org/W3012421327","https://openalex.org/W3015595381","https://openalex.org/W3023991776","https://openalex.org/W3024643080","https://openalex.org/W3037490455","https://openalex.org/W3041960835","https://openalex.org/W3094941923","https://openalex.org/W3119467713","https://openalex.org/W3121407008","https://openalex.org/W3124872736","https://openalex.org/W3128412820","https://openalex.org/W3133745688","https://openalex.org/W3161424923","https://openalex.org/W3167203305","https://openalex.org/W3182807823","https://openalex.org/W3185199984","https://openalex.org/W3196698228","https://openalex.org/W3196816405","https://openalex.org/W3201970916","https://openalex.org/W3213735671","https://openalex.org/W4200343754","https://openalex.org/W4200600872","https://openalex.org/W4206271948","https://openalex.org/W4206979825","https://openalex.org/W4210680889","https://openalex.org/W4210686331","https://openalex.org/W4220784902","https://openalex.org/W4255815262","https://openalex.org/W4283066294","https://openalex.org/W4283511977","https://openalex.org/W4283707533","https://openalex.org/W4286560188","https://openalex.org/W4289344811","https://openalex.org/W4293576643","https://openalex.org/W4306168964","https://openalex.org/W4309878498","https://openalex.org/W4315436426","https://openalex.org/W4317390883","https://openalex.org/W4321446752","https://openalex.org/W4366210828"],"related_works":["https://openalex.org/W3036314732","https://openalex.org/W3009669391","https://openalex.org/W3176864053","https://openalex.org/W4206669628","https://openalex.org/W3171943759","https://openalex.org/W4292098121","https://openalex.org/W3154141118","https://openalex.org/W4388896133","https://openalex.org/W3031607536","https://openalex.org/W4205317059"],"abstract_inverted_index":{"The":[0],"long-term":[1,289],"impacts":[2,290],"of":[3,15,31,84,267,275,291],"COVID-19":[4,37,60,95,148,179,245,280,292],"on":[5,18,87,184,293],"human":[6,294],"health":[7,20,283],"are":[8,22],"a":[9,43,272],"major":[10],"concern,":[11],"yet":[12],"comprehensive":[13,273,316],"evaluations":[14],"its":[16],"effects":[17,183],"various":[19,32],"conditions":[21],"lacking.":[23],"This":[24,269],"study":[25,270],"aims":[26],"to":[27,36,80,153,253,263,314],"evaluate":[28],"the":[29,82,259,265,276,288,297],"role":[30],"diseases":[33,70,86],"in":[34],"relation":[35],"by":[38],"analyzing":[39],"genetic":[40],"data":[41],"from":[42],"large-scale":[44],"population":[45],"over":[46],"2,000,000":[47],"individuals.":[48,307],"A":[49,73],"bidirectional":[50],"two-sample":[51],"Mendelian":[52,75],"randomization":[53,76],"approach":[54],"was":[55,78,150],"used,":[56],"with":[57],"exposures":[58],"including":[59,100],"susceptibility,":[61],"hospitalization,":[62],"and":[63,65,97,135,166,216,240,250,257,281,302],"severity,":[64],"outcomes":[66],"encompassing":[67],"86":[68],"different":[69],"or":[71],"traits.":[72],"reverse":[74],"analysis":[77,90,231,274],"performed":[79],"assess":[81],"impact":[83],"these":[85,312],"COVID-19.":[88],"Our":[89,285],"identified":[91],"causal":[92,182,277],"relationships":[93,278,313],"between":[94,279],"susceptibility":[96],"several":[98],"conditions,":[99],"breast":[101,119],"cancer":[102,120],"(OR":[103,121,138,156,169,188,204,219],"=":[104,108,111,122,126,129,139,143,146,157,161,164,170,174,177,189,193,196,205,209,212,220,224,227],"1.0073,":[105],"95%":[106,124,141,159,172,191,207,222],"CI":[107,125,142,160,173,192,208,223],"1.0032\u20131.0114,":[109],"p":[110,128,145,163,176,195,211,226],"5":[112],"\u00d7":[113,131,198,214],"10":[114,132,199],"\u2212":[115,133,200],"4),":[116,134],"ER":[117],"+":[118],"0.5252,":[123],"0.3589\u20130.7685,":[127],"9":[130],"heart":[136,154],"failure":[137,155],"1.0026,":[140],"1.001\u20131.0042,":[144],"0.002).":[147],"hospitalization":[149],"causally":[151],"linked":[152],"1.0017,":[158],"1.0006\u20131.0028,":[162],"0.002)":[165],"Alzheimer\u2019s":[167,217],"disease":[168,203,218],"1.5092,":[171,221],"1.1942\u20131.9072,":[175,225],"0.0006).":[178,228],"severity":[180],"had":[181],"primary":[185],"biliary":[186],"cirrhosis":[187],"2.6333,":[190],"1.8274\u20133.7948,":[194],"2.059":[197],"7),":[201],"celiac":[202],"0.0708,":[206],"0.0538\u20130.0932,":[210],"9.438":[213],"10\u201380),":[215],"Reverse":[229],"MR":[230],"indicated":[232],"that":[233],"rheumatoid":[234],"arthritis,":[235],"diabetic":[236],"nephropathy,":[237],"multiple":[238],"sclerosis,":[239],"total":[241],"testosterone":[242],"(female)":[243],"influence":[244],"outcomes.":[246],"We":[247],"assessed":[248],"heterogeneity":[249],"horizontal":[251],"pleiotropy":[252],"ensure":[254],"result":[255],"reliability":[256],"employed":[258],"Steiger":[260],"directionality":[261],"test":[262],"confirm":[264],"direction":[266],"causality.":[268],"provides":[271],"diverse":[282],"conditions.":[284],"findings":[286],"highlight":[287],"health,":[295],"emphasizing":[296],"need":[298],"for":[299,305],"continuous":[300],"monitoring":[301],"targeted":[303],"interventions":[304],"affected":[306],"Future":[308],"research":[309],"should":[310],"explore":[311],"develop":[315],"healthcare":[317],"strategies.":[318]},"counts_by_year":[{"year":2025,"cited_by_count":1}],"updated_date":"2026-04-16T08:26:57.006410","created_date":"2025-10-10T00:00:00"}
