{"id":"https://openalex.org/W2756060357","doi":"https://doi.org/10.1186/s13326-017-0146-9","title":"Towards precision medicine: discovering novel gynecological cancer biomarkers and pathways using linked data","display_name":"Towards precision medicine: discovering novel gynecological cancer biomarkers and pathways using linked data","publication_year":2017,"publication_date":"2017-09-19","ids":{"openalex":"https://openalex.org/W2756060357","doi":"https://doi.org/10.1186/s13326-017-0146-9","mag":"2756060357","pmid":"https://pubmed.ncbi.nlm.nih.gov/28927463"},"language":"en","primary_location":{"id":"doi:10.1186/s13326-017-0146-9","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13326-017-0146-9","pdf_url":"https://jbiomedsem.biomedcentral.com/track/pdf/10.1186/s13326-017-0146-9","source":{"id":"https://openalex.org/S172276550","display_name":"Journal of Biomedical Semantics","issn_l":"2041-1480","issn":["2041-1480"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biomedical Semantics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://jbiomedsem.biomedcentral.com/track/pdf/10.1186/s13326-017-0146-9","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5011470209","display_name":"Alokkumar Jha","orcid":"https://orcid.org/0000-0002-8024-5854"},"institutions":[{"id":"https://openalex.org/I188760350","display_name":"Ollscoil na Gaillimhe \u2013 University of Galway","ror":"https://ror.org/03bea9k73","country_code":"IE","type":"education","lineage":["https://openalex.org/I188760350"]}],"countries":["IE"],"is_corresponding":true,"raw_author_name":"Alokkumar Jha","raw_affiliation_strings":["Insight Centre for Data Analytics, NUIG, Galway, Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Insight Centre for Data Analytics, NUIG, Galway, Ireland","institution_ids":["https://openalex.org/I188760350"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045342137","display_name":"Yasar Khan","orcid":"https://orcid.org/0000-0003-1049-1977"},"institutions":[{"id":"https://openalex.org/I188760350","display_name":"Ollscoil na Gaillimhe \u2013 University of Galway","ror":"https://ror.org/03bea9k73","country_code":"IE","type":"education","lineage":["https://openalex.org/I188760350"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Yasar Khan","raw_affiliation_strings":["Insight Centre for Data Analytics, NUIG, Galway, Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Insight Centre for Data Analytics, NUIG, Galway, Ireland","institution_ids":["https://openalex.org/I188760350"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102991530","display_name":"Muntazir Mehdi","orcid":"https://orcid.org/0009-0005-6622-4714"},"institutions":[{"id":"https://openalex.org/I188760350","display_name":"Ollscoil na Gaillimhe \u2013 University of Galway","ror":"https://ror.org/03bea9k73","country_code":"IE","type":"education","lineage":["https://openalex.org/I188760350"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Muntazir Mehdi","raw_affiliation_strings":["Insight Centre for Data Analytics, NUIG, Galway, Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Insight Centre for Data Analytics, NUIG, Galway, Ireland","institution_ids":["https://openalex.org/I188760350"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007534068","display_name":"Md Rezaul Karim","orcid":"https://orcid.org/0000-0001-5461-7709"},"institutions":[{"id":"https://openalex.org/I188760350","display_name":"Ollscoil na Gaillimhe \u2013 University of Galway","ror":"https://ror.org/03bea9k73","country_code":"IE","type":"education","lineage":["https://openalex.org/I188760350"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Md Rezaul Karim","raw_affiliation_strings":["Insight Centre for Data Analytics, NUIG, Galway, Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Insight Centre for Data Analytics, NUIG, Galway, Ireland","institution_ids":["https://openalex.org/I188760350"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044073014","display_name":"Qaiser Mehmood","orcid":"https://orcid.org/0000-0002-1380-1750"},"institutions":[{"id":"https://openalex.org/I188760350","display_name":"Ollscoil na Gaillimhe \u2013 University of Galway","ror":"https://ror.org/03bea9k73","country_code":"IE","type":"education","lineage":["https://openalex.org/I188760350"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Qaiser Mehmood","raw_affiliation_strings":["Insight Centre for Data Analytics, NUIG, Galway, Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Insight Centre for Data Analytics, NUIG, Galway, Ireland","institution_ids":["https://openalex.org/I188760350"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034664449","display_name":"Achille Zappa","orcid":"https://orcid.org/0000-0003-4040-9620"},"institutions":[{"id":"https://openalex.org/I188760350","display_name":"Ollscoil na Gaillimhe \u2013 University of Galway","ror":"https://ror.org/03bea9k73","country_code":"IE","type":"education","lineage":["https://openalex.org/I188760350"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Achille Zappa","raw_affiliation_strings":["Insight Centre for Data Analytics, NUIG, Galway, Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Insight Centre for Data Analytics, NUIG, Galway, Ireland","institution_ids":["https://openalex.org/I188760350"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006224704","display_name":"Dietrich Rebholz\u2010Schuhmann","orcid":"https://orcid.org/0000-0002-1018-0370"},"institutions":[{"id":"https://openalex.org/I188760350","display_name":"Ollscoil na Gaillimhe \u2013 University of Galway","ror":"https://ror.org/03bea9k73","country_code":"IE","type":"education","lineage":["https://openalex.org/I188760350"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Dietrich Rebholz-Schuhmann","raw_affiliation_strings":["Insight Centre for Data Analytics, NUIG, Galway, Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Insight Centre for Data Analytics, NUIG, Galway, Ireland","institution_ids":["https://openalex.org/I188760350"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5058460371","display_name":"Ratnesh Sahay","orcid":"https://orcid.org/0000-0003-4864-4174"},"institutions":[{"id":"https://openalex.org/I188760350","display_name":"Ollscoil na Gaillimhe \u2013 University of Galway","ror":"https://ror.org/03bea9k73","country_code":"IE","type":"education","lineage":["https://openalex.org/I188760350"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Ratnesh Sahay","raw_affiliation_strings":["Insight Centre for Data Analytics, NUIG, Galway, Ireland. ratnesh.sahay@insight-centre.org","Insight Centre for Data Analytics, NUIG, Galway, Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Insight Centre for Data Analytics, NUIG, Galway, Ireland. ratnesh.sahay@insight-centre.org","institution_ids":[]},{"raw_affiliation_string":"Insight Centre for Data Analytics, NUIG, Galway, Ireland","institution_ids":["https://openalex.org/I188760350"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5011470209"],"corresponding_institution_ids":["https://openalex.org/I188760350"],"apc_list":{"value":1190,"currency":"GBP","value_usd":1459},"apc_paid":{"value":1190,"currency":"GBP","value_usd":1459},"fwci":1.3674,"has_fulltext":true,"cited_by_count":22,"citation_normalized_percentile":{"value":0.78834779,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"8","issue":"1","first_page":"40","last_page":"40"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.3935000002384186,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.3935000002384186,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.07850000262260437,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10668","display_name":"Endometrial and Cervical Cancer Treatments","score":0.05480000004172325,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7211139798164368},{"id":"https://openalex.org/keywords/precision-medicine","display_name":"Precision medicine","score":0.6280579566955566},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.49560248851776123},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.35961538553237915},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.33072930574417114},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.2302468717098236},{"id":"https://openalex.org/keywords/pathology","display_name":"Pathology","score":0.11055272817611694},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.10076287388801575}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7211139798164368},{"id":"https://openalex.org/C163763905","wikidata":"https://www.wikidata.org/wiki/Q17075943","display_name":"Precision medicine","level":2,"score":0.6280579566955566},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.49560248851776123},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.35961538553237915},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.33072930574417114},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2302468717098236},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.11055272817611694},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.10076287388801575}],"mesh":[{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005831","descriptor_name":"Genital Diseases, Female","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005831","descriptor_name":"Genital Diseases, Female","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005831","descriptor_name":"Genital Diseases, Female","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008490","descriptor_name":"Medical Informatics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008490","descriptor_name":"Medical Informatics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008490","descriptor_name":"Medical Informatics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057225","descriptor_name":"Data Mining","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057225","descriptor_name":"Data Mining","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057225","descriptor_name":"Data Mining","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057285","descriptor_name":"Precision Medicine","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D057285","descriptor_name":"Precision Medicine","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D057285","descriptor_name":"Precision Medicine","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1186/s13326-017-0146-9","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13326-017-0146-9","pdf_url":"https://jbiomedsem.biomedcentral.com/track/pdf/10.1186/s13326-017-0146-9","source":{"id":"https://openalex.org/S172276550","display_name":"Journal of Biomedical Semantics","issn_l":"2041-1480","issn":["2041-1480"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biomedical Semantics","raw_type":"journal-article"},{"id":"pmid:28927463","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28927463","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of biomedical semantics","raw_type":null},{"id":"pmh:oai:https://researchrepository.universityofgalway.ie:10379/7453","is_oa":true,"landing_page_url":"http://hdl.handle.net/10379/7453","pdf_url":"http://hdl.handle.net/10379/7453","source":{"id":"https://openalex.org/S4377196322","display_name":"ARAN (University of Galway Research Repository) (Ollscoil na Gaillimhe \u2013 University of Galway)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I188760350","host_organization_name":"Ollscoil na Gaillimhe \u2013 University of Galway","host_organization_lineage":["https://openalex.org/I188760350"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"journal article"},{"id":"pmh:http://www.rian.ie/159803/","is_oa":false,"landing_page_url":"http://hdl.handle.net/10379/12090","pdf_url":null,"source":{"id":"https://openalex.org/S4306400033","display_name":"Arrow@dit (Dublin Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I115570527","host_organization_name":"Dublin Institute of Technology","host_organization_lineage":["https://openalex.org/I115570527"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Journal article"},{"id":"pmh:oai:doaj.org/article:8281318399624813b3bea53eabbc22a3","is_oa":true,"landing_page_url":"https://doaj.org/article/8281318399624813b3bea53eabbc22a3","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Biomedical Semantics, Vol 8, Iss 1, Pp 1-16 (2017)","raw_type":"article"},{"id":"pmh:oai:europepmc.org:4531845","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5606033","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/s13326-017-0146-9","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13326-017-0146-9","pdf_url":"https://jbiomedsem.biomedcentral.com/track/pdf/10.1186/s13326-017-0146-9","source":{"id":"https://openalex.org/S172276550","display_name":"Journal of Biomedical Semantics","issn_l":"2041-1480","issn":["2041-1480"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biomedical Semantics","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.46000000834465027,"id":"https://metadata.un.org/sdg/3"}],"awards":[{"id":"https://openalex.org/G1383882326","display_name":null,"funder_award_id":"SFI/12/RC/","funder_id":"https://openalex.org/F4320320847","funder_display_name":"Science Foundation Ireland"},{"id":"https://openalex.org/G2881606312","display_name":null,"funder_award_id":"SFI/12/RC/2289","funder_id":"https://openalex.org/F4320320847","funder_display_name":"Science Foundation Ireland"},{"id":"https://openalex.org/G5098725405","display_name":null,"funder_award_id":"12/RC/","funder_id":"https://openalex.org/F4320320847","funder_display_name":"Science Foundation Ireland"},{"id":"https://openalex.org/G6654329577","display_name":null,"funder_award_id":"Grant Number SFI/12/RC/2289","funder_id":"https://openalex.org/F4320320847","funder_display_name":"Science Foundation Ireland"},{"id":"https://openalex.org/G7362007176","display_name":null,"funder_award_id":"12/RC/2289","funder_id":"https://openalex.org/F4320320847","funder_display_name":"Science Foundation Ireland"}],"funders":[{"id":"https://openalex.org/F4320320847","display_name":"Science Foundation Ireland","ror":"https://ror.org/0271asj38"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2756060357.pdf","grobid_xml":"https://content.openalex.org/works/W2756060357.grobid-xml"},"referenced_works_count":51,"referenced_works":["https://openalex.org/W153622350","https://openalex.org/W1484056211","https://openalex.org/W1513665907","https://openalex.org/W1589531606","https://openalex.org/W1805140197","https://openalex.org/W1969361257","https://openalex.org/W1976848056","https://openalex.org/W1977046764","https://openalex.org/W2022495797","https://openalex.org/W2023910541","https://openalex.org/W2040657105","https://openalex.org/W2044202003","https://openalex.org/W2051380427","https://openalex.org/W2062419920","https://openalex.org/W2096451658","https://openalex.org/W2097678794","https://openalex.org/W2100305481","https://openalex.org/W2104060732","https://openalex.org/W2104846587","https://openalex.org/W2105821863","https://openalex.org/W2114843025","https://openalex.org/W2117726975","https://openalex.org/W2120010083","https://openalex.org/W2121906867","https://openalex.org/W2124386633","https://openalex.org/W2130153722","https://openalex.org/W2140430468","https://openalex.org/W2142838294","https://openalex.org/W2145116858","https://openalex.org/W2152026276","https://openalex.org/W2152577585","https://openalex.org/W2158948118","https://openalex.org/W2160860814","https://openalex.org/W2165428180","https://openalex.org/W2165901933","https://openalex.org/W2169589032","https://openalex.org/W2248646379","https://openalex.org/W2272037513","https://openalex.org/W2288397551","https://openalex.org/W2293532363","https://openalex.org/W2345889990","https://openalex.org/W2396849069","https://openalex.org/W2397367475","https://openalex.org/W2398915717","https://openalex.org/W2526413677","https://openalex.org/W2584060050","https://openalex.org/W3041537557","https://openalex.org/W4210449250","https://openalex.org/W4213083935","https://openalex.org/W6611748842","https://openalex.org/W6683929587"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2899084033","https://openalex.org/W2748952813","https://openalex.org/W2390279801","https://openalex.org/W4391913857","https://openalex.org/W2358668433","https://openalex.org/W4396701345","https://openalex.org/W2376932109","https://openalex.org/W2001405890","https://openalex.org/W4396696052"],"abstract_inverted_index":{"BACKGROUND:":[0],"Next":[1],"Generation":[2],"Sequencing":[3],"(NGS)":[4],"is":[5,244],"playing":[6],"a":[7,25,179,228],"key":[8,242],"role":[9],"in":[10,166,221,279,308],"therapeutic":[11],"decision":[12],"making":[13],"for":[14,110,178],"the":[15,37,44,59,71,76,79,137,162,173,185],"cancer":[16,112,224,237,259,264,297],"prognosis":[17],"and":[18,39,48,84,96,105,131,168,196,203,213,238,254,287,290,317],"treatment.":[19],"The":[20,148,241,271],"NGS":[21],"technologies":[22],"are":[23,34,53,158],"producing":[24],"massive":[26],"amount":[27],"of":[28,46,73,78,175,188],"sequencing":[29,41,51,99],"datasets.":[30],"Often,":[31],"these":[32],"datasets":[33,52,100,260,289],"published":[35],"from":[36,65,142,152,266,282,299],"isolated":[38,258],"different":[40,66,98,222],"facilities.":[42],"Consequently,":[43],"process":[45],"sharing":[47],"aggregating":[49],"multisite":[50],"thwarted":[54],"by":[55,277],"issues":[56],"such":[57],"as":[58],"need":[60],"to":[61,94,107,172,199,245,268,295,301,311],"discover":[62,174],"relevant":[63],"data":[64,74,249],"sources,":[67],"built":[68],"scalable":[69],"repositories,":[70],"automation":[72],"linkage,":[75],"volume":[77],"data,":[80],"efficient":[81],"querying":[82],"mechanism,":[83],"information":[85],"rich":[86],"intuitive":[87],"visualisation.":[88],"RESULTS:":[89],"We":[90,183,207,226],"present":[91],"an":[92,292],"approach":[93,243],"link":[95],"query":[97],"(TCGA,":[101],"COSMIC,":[102,284],"REACTOME,":[103,285],"KEGG":[104,286],"GO)":[106],"indicate":[108],"risks":[109],"four":[111],"types":[113],"-":[114,135],"Ovarian":[115],"Serous":[116],"Cystadenocarcinoma":[117],"(OV),":[118],"Uterine":[119,124],"Corpus":[120],"Endometrial":[121],"Carcinoma":[122,130],"(UCEC),":[123],"Carcinosarcoma":[125],"(UCS),":[126],"Cervical":[127],"Squamous":[128],"Cell":[129],"Endocervical":[132],"Adenocarcinoma":[133],"(CESC)":[134],"covering":[136],"16":[138],"healthy":[139],"tissue-specific":[140,180],"genes":[141,151,212],"Illumina":[143,153],"Human":[144,154],"Body":[145,155],"Map":[146,156],"2.0.":[147],"differentially":[149],"expressed":[150],"2.0":[157],"analysed":[159],"together":[160,235],"with":[161,304],"gene":[163],"expressions":[164],"reported":[165],"COSMIC":[167],"TCGA":[169],"repositories":[170],"leading":[171],"potential":[176,216],"biomarkers":[177],"cancer.":[181],"CONCLUSION:":[182],"analyse":[184],"tissue":[186],"expression":[187],"genes,":[189],"copy":[190],"number":[191],"variation":[192],"(CNV),":[193],"somatic":[194],"mutation,":[195],"promoter":[197,219],"methylation":[198],"identify":[200],"associated":[201,314],"pathways":[202,217],"find":[204,246],"novel":[205],"biomarkers.":[206],"discovered":[208],"twenty":[209],"(20)":[210],"mutated":[211],"three":[214],"(3)":[215],"causing":[218],"changes":[220],"gynaecological":[223],"types.":[225],"propose":[227],"data-interlinked":[229],"platform":[230,274],"called":[231],"BIOOPENER":[232,273],"that":[233],"glues":[234],"heterogeneous":[236],"biomedical":[239],"repositories.":[240],"correspondences":[247],"(or":[248],"links)":[250],"among":[251],"genetic,":[252],"cellular":[253],"molecular":[255],"features":[256],"across":[257],"giving":[261],"insight":[262],"into":[263],"progression":[265,298],"normal":[267,300],"diseased":[269,302],"tissues.":[270],"proposed":[272],"enriches":[275],"mutations":[276],"filling":[278],"missing":[280],"links":[281],"TCGA,":[283],"GO":[288],"provides":[291],"interlinking":[293],"mechanism":[294],"understand":[296],"tissues":[303],"pathway":[305],"components,":[306],"which":[307],"turn":[309],"helped":[310],"map":[312],"mutations,":[313],"phenotypes,":[315],"pathways,":[316],"mechanism.":[318]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":3},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":1}],"updated_date":"2026-05-06T08:25:59.206177","created_date":"2025-10-10T00:00:00"}
