{"id":"https://openalex.org/W4327676467","doi":"https://doi.org/10.1186/s13321-023-00690-3","title":"DFFNDDS: prediction of synergistic drug combinations with dual feature fusion networks","display_name":"DFFNDDS: prediction of synergistic drug combinations with dual feature fusion networks","publication_year":2023,"publication_date":"2023-03-16","ids":{"openalex":"https://openalex.org/W4327676467","doi":"https://doi.org/10.1186/s13321-023-00690-3","pmid":"https://pubmed.ncbi.nlm.nih.gov/36927504"},"language":"en","primary_location":{"id":"doi:10.1186/s13321-023-00690-3","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13321-023-00690-3","pdf_url":"https://jcheminf.biomedcentral.com/counter/pdf/10.1186/s13321-023-00690-3","source":{"id":"https://openalex.org/S180838163","display_name":"Journal of Cheminformatics","issn_l":"1758-2946","issn":["1758-2946"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Cheminformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://jcheminf.biomedcentral.com/counter/pdf/10.1186/s13321-023-00690-3","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5009724929","display_name":"Mengdie Xu","orcid":null},"institutions":[{"id":"https://openalex.org/I83519826","display_name":"Nanjing Medical University","ror":"https://ror.org/059gcgy73","country_code":"CN","type":"education","lineage":["https://openalex.org/I83519826"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Mengdie Xu","raw_affiliation_strings":["Department of Medical Informatics, School of Biomedical Engineering and Informatics, Nanjing Medical University, Nanjing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Informatics, School of Biomedical Engineering and Informatics, Nanjing Medical University, Nanjing, China","institution_ids":["https://openalex.org/I83519826"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101857711","display_name":"Xinwei Zhao","orcid":"https://orcid.org/0000-0002-4328-4846"},"institutions":[{"id":"https://openalex.org/I83519826","display_name":"Nanjing Medical University","ror":"https://ror.org/059gcgy73","country_code":"CN","type":"education","lineage":["https://openalex.org/I83519826"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xinwei Zhao","raw_affiliation_strings":["Department of Medical Informatics, School of Biomedical Engineering and Informatics, Nanjing Medical University, Nanjing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Informatics, School of Biomedical Engineering and Informatics, Nanjing Medical University, Nanjing, China","institution_ids":["https://openalex.org/I83519826"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100432460","display_name":"Jingyu Wang","orcid":"https://orcid.org/0000-0002-2182-2228"},"institutions":[{"id":"https://openalex.org/I83519826","display_name":"Nanjing Medical University","ror":"https://ror.org/059gcgy73","country_code":"CN","type":"education","lineage":["https://openalex.org/I83519826"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jingyu Wang","raw_affiliation_strings":["Department of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing, China","Department of Medical Informatics, School of Biomedical Engineering and Informatics, Nanjing Medical University, Nanjing, China","Institute of Medical Informatics and Management, Nanjing Medical University, No. 300 Guang Zhou Road, Nanjing, 210029, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing, China","institution_ids":["https://openalex.org/I83519826"]},{"raw_affiliation_string":"Department of Medical Informatics, School of Biomedical Engineering and Informatics, Nanjing Medical University, Nanjing, China","institution_ids":["https://openalex.org/I83519826"]},{"raw_affiliation_string":"Institute of Medical Informatics and Management, Nanjing Medical University, No. 300 Guang Zhou Road, Nanjing, 210029, China","institution_ids":["https://openalex.org/I83519826"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081703144","display_name":"Wei Feng","orcid":"https://orcid.org/0000-0002-9993-8722"},"institutions":[{"id":"https://openalex.org/I83519826","display_name":"Nanjing Medical University","ror":"https://ror.org/059gcgy73","country_code":"CN","type":"education","lineage":["https://openalex.org/I83519826"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wei Feng","raw_affiliation_strings":["Department of Medical Informatics, School of Biomedical Engineering and Informatics, Nanjing Medical University, Nanjing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Informatics, School of Biomedical Engineering and Informatics, Nanjing Medical University, Nanjing, China","institution_ids":["https://openalex.org/I83519826"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091740913","display_name":"Naifeng Wen","orcid":"https://orcid.org/0000-0003-2725-8645"},"institutions":[{"id":"https://openalex.org/I61565387","display_name":"Dalian Minzu University","ror":"https://ror.org/02hxfx521","country_code":"CN","type":"education","lineage":["https://openalex.org/I61565387"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Naifeng Wen","raw_affiliation_strings":["School of Mechanical and Electrical Engineering, Dalian Minzu University, Dalian, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Mechanical and Electrical Engineering, Dalian Minzu University, Dalian, China","institution_ids":["https://openalex.org/I61565387"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070849202","display_name":"Chunyu Wang","orcid":"https://orcid.org/0000-0002-2965-9920"},"institutions":[{"id":"https://openalex.org/I204983213","display_name":"Harbin Institute of Technology","ror":"https://ror.org/01yqg2h08","country_code":"CN","type":"education","lineage":["https://openalex.org/I204983213"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chunyu Wang","raw_affiliation_strings":["Faculty of Computing, Harbin Institute of Technology, Harbin, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Computing, Harbin Institute of Technology, Harbin, China","institution_ids":["https://openalex.org/I204983213"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100395816","display_name":"Junjie Wang","orcid":"https://orcid.org/0000-0003-0732-051X"},"institutions":[{"id":"https://openalex.org/I83519826","display_name":"Nanjing Medical University","ror":"https://ror.org/059gcgy73","country_code":"CN","type":"education","lineage":["https://openalex.org/I83519826"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Junjie Wang","raw_affiliation_strings":["Department of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing, China","Department of Medical Informatics, School of Biomedical Engineering and Informatics, Nanjing Medical University, Nanjing, China","Institute of Medical Informatics and Management, Nanjing Medical University, No. 300 Guang Zhou Road, Nanjing, 210029, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing, China","institution_ids":["https://openalex.org/I83519826"]},{"raw_affiliation_string":"Department of Medical Informatics, School of Biomedical Engineering and Informatics, Nanjing Medical University, Nanjing, China","institution_ids":["https://openalex.org/I83519826"]},{"raw_affiliation_string":"Institute of Medical Informatics and Management, Nanjing Medical University, No. 300 Guang Zhou Road, Nanjing, 210029, China","institution_ids":["https://openalex.org/I83519826"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5115602468","display_name":"Yun Liu","orcid":"https://orcid.org/0000-0003-4377-1211"},"institutions":[{"id":"https://openalex.org/I83519826","display_name":"Nanjing Medical University","ror":"https://ror.org/059gcgy73","country_code":"CN","type":"education","lineage":["https://openalex.org/I83519826"]},{"id":"https://openalex.org/I4210152119","display_name":"Jiangsu Province Hospital","ror":"https://ror.org/04py1g812","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210152119"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Yun Liu","raw_affiliation_strings":["Department of Information, First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China. liuyun@njmu.edu.cn","Department of Medical Informatics, School of Biomedical Engineering and Informatics, Nanjing Medical University, Nanjing, China. liuyun@njmu.edu.cn","Institute of Medical Informatics and Management, Nanjing Medical University, No. 300 Guang Zhou Road, Nanjing, 210029, China. liuyun@njmu.edu.cn","Department of Information, First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Information, First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China. liuyun@njmu.edu.cn","institution_ids":["https://openalex.org/I83519826"]},{"raw_affiliation_string":"Department of Medical Informatics, School of Biomedical Engineering and Informatics, Nanjing Medical University, Nanjing, China. liuyun@njmu.edu.cn","institution_ids":["https://openalex.org/I83519826"]},{"raw_affiliation_string":"Institute of Medical Informatics and Management, Nanjing Medical University, No. 300 Guang Zhou Road, Nanjing, 210029, China. liuyun@njmu.edu.cn","institution_ids":["https://openalex.org/I83519826"]},{"raw_affiliation_string":"Department of Information, First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China","institution_ids":["https://openalex.org/I83519826","https://openalex.org/I4210152119"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5012585076","display_name":"Lingling Zhao","orcid":"https://orcid.org/0000-0002-2808-3771"},"institutions":[{"id":"https://openalex.org/I204983213","display_name":"Harbin Institute of Technology","ror":"https://ror.org/01yqg2h08","country_code":"CN","type":"education","lineage":["https://openalex.org/I204983213"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lingling Zhao","raw_affiliation_strings":["Faculty of Computing, Harbin Institute of Technology, Harbin, China. zhaoll@hit.edu.cn","Faculty of Computing, Harbin Institute of Technology, Harbin, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Computing, Harbin Institute of Technology, Harbin, China. zhaoll@hit.edu.cn","institution_ids":["https://openalex.org/I204983213"]},{"raw_affiliation_string":"Faculty of Computing, Harbin Institute of Technology, Harbin, China","institution_ids":["https://openalex.org/I204983213"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5115602468"],"corresponding_institution_ids":["https://openalex.org/I4210152119","https://openalex.org/I83519826"],"apc_list":{"value":1290,"currency":"GBP","value_usd":1582},"apc_paid":{"value":1290,"currency":"GBP","value_usd":1582},"fwci":11.8527,"has_fulltext":true,"cited_by_count":61,"citation_normalized_percentile":{"value":0.98916342,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"15","issue":"1","first_page":"33","last_page":"33"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10375","display_name":"Pharmacogenetics and Drug Metabolism","score":0.9302999973297119,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14351","display_name":"Statistical and Computational Modeling","score":0.9180999994277954,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6923310160636902},{"id":"https://openalex.org/keywords/dual","display_name":"Dual (grammatical number)","score":0.6581336259841919},{"id":"https://openalex.org/keywords/feature","display_name":"Feature (linguistics)","score":0.6044162511825562},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.5208340287208557},{"id":"https://openalex.org/keywords/drug","display_name":"Drug","score":0.4517589509487152},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.40231919288635254},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.38605549931526184},{"id":"https://openalex.org/keywords/pharmacology","display_name":"Pharmacology","score":0.17375949025154114},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.11212477087974548}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6923310160636902},{"id":"https://openalex.org/C2780980858","wikidata":"https://www.wikidata.org/wiki/Q110022","display_name":"Dual (grammatical number)","level":2,"score":0.6581336259841919},{"id":"https://openalex.org/C2776401178","wikidata":"https://www.wikidata.org/wiki/Q12050496","display_name":"Feature (linguistics)","level":2,"score":0.6044162511825562},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.5208340287208557},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.4517589509487152},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.40231919288635254},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.38605549931526184},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.17375949025154114},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.11212477087974548},{"id":"https://openalex.org/C124952713","wikidata":"https://www.wikidata.org/wiki/Q8242","display_name":"Literature","level":1,"score":0.0},{"id":"https://openalex.org/C142362112","wikidata":"https://www.wikidata.org/wiki/Q735","display_name":"Art","level":0,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1186/s13321-023-00690-3","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13321-023-00690-3","pdf_url":"https://jcheminf.biomedcentral.com/counter/pdf/10.1186/s13321-023-00690-3","source":{"id":"https://openalex.org/S180838163","display_name":"Journal of Cheminformatics","issn_l":"1758-2946","issn":["1758-2946"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Cheminformatics","raw_type":"journal-article"},{"id":"pmid:36927504","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36927504","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of cheminformatics","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:10022091","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10022091","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10022091/pdf/13321_2023_Article_690.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"J Cheminform","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:a9e513e8ffaa487dad14dde48a5f1407","is_oa":true,"landing_page_url":"https://doaj.org/article/a9e513e8ffaa487dad14dde48a5f1407","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Cheminformatics, Vol 15, Iss 1, Pp 1-12 (2023)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/s13321-023-00690-3","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13321-023-00690-3","pdf_url":"https://jcheminf.biomedcentral.com/counter/pdf/10.1186/s13321-023-00690-3","source":{"id":"https://openalex.org/S180838163","display_name":"Journal of Cheminformatics","issn_l":"1758-2946","issn":["1758-2946"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Cheminformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.5899999737739563,"id":"https://metadata.un.org/sdg/3"}],"awards":[{"id":"https://openalex.org/G1365216518","display_name":null,"funder_award_id":"BE2020721","funder_id":"https://openalex.org/F4320325437","funder_display_name":"Jiangsu Science and Technology Department"},{"id":"https://openalex.org/G2577386298","display_name":null,"funder_award_id":"JX12413925","funder_id":"https://openalex.org/F4320335769","funder_display_name":"Graduate Research and Innovation Projects of Jiangsu Province"},{"id":"https://openalex.org/G3111323395","display_name":null,"funder_award_id":"62271174","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G8597864016","display_name":null,"funder_award_id":"62102191","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320321605","display_name":"Government of Jiangsu Province","ror":"https://ror.org/004svx814"},{"id":"https://openalex.org/F4320325437","display_name":"Jiangsu Science and Technology Department","ror":null},{"id":"https://openalex.org/F4320335769","display_name":"Graduate Research and Innovation Projects of Jiangsu Province","ror":null}],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W4327676467.pdf"},"referenced_works_count":33,"referenced_works":["https://openalex.org/W1964940342","https://openalex.org/W1977863938","https://openalex.org/W2040112396","https://openalex.org/W2044025814","https://openalex.org/W2052468572","https://openalex.org/W2140239055","https://openalex.org/W2166082449","https://openalex.org/W2505616932","https://openalex.org/W2518259126","https://openalex.org/W2551072359","https://openalex.org/W2565209476","https://openalex.org/W2775061087","https://openalex.org/W2883248903","https://openalex.org/W2892948265","https://openalex.org/W2945591540","https://openalex.org/W2950860419","https://openalex.org/W2960677646","https://openalex.org/W2970771982","https://openalex.org/W2982291409","https://openalex.org/W3006386963","https://openalex.org/W3037025949","https://openalex.org/W3039265083","https://openalex.org/W3101756747","https://openalex.org/W3102794373","https://openalex.org/W3107514561","https://openalex.org/W3144293453","https://openalex.org/W3156636935","https://openalex.org/W3164087725","https://openalex.org/W3165195325","https://openalex.org/W3172530361","https://openalex.org/W3203908308","https://openalex.org/W6601548533","https://openalex.org/W6702248584"],"related_works":["https://openalex.org/W4206379684","https://openalex.org/W2317351040","https://openalex.org/W2952466936","https://openalex.org/W3147584709","https://openalex.org/W1988622314","https://openalex.org/W2393949104","https://openalex.org/W3046201198","https://openalex.org/W2366105490","https://openalex.org/W2580680567","https://openalex.org/W4293061921"],"abstract_inverted_index":{"Drug":[0],"combination":[1],"therapies":[2],"are":[3],"promising":[4],"clinical":[5],"treatments":[6],"for":[7,42,99],"curing":[8],"patients.":[9],"However,":[10],"efficiently":[11],"identifying":[12,100],"valid":[13],"drug":[14,62,71,102],"combinations":[15],"remains":[16],"challenging":[17],"because":[18],"the":[19,37,70,78,82],"number":[20],"of":[21],"available":[22],"drugs":[23],"has":[24],"increased":[25],"rapidly.":[26],"In":[27],"this":[28],"study,":[29],"we":[30],"proposed":[31],"a":[32,49,96],"deep":[33],"learning":[34],"model":[35,53],"called":[36],"Dual":[38],"Feature":[39],"Fusion":[40],"Network":[41],"Drug-Drug":[43],"Synergy":[44],"prediction":[45],"(DFFNDDS)":[46],"that":[47,87],"utilizes":[48],"fine-tuned":[50],"pretrained":[51],"language":[52],"and":[54,73,81,92],"dual":[55,65],"feature":[56,66],"fusion":[57,67],"mechanism":[58,68],"to":[59],"predict":[60],"synergistic":[61,101],"combinations.":[63,103],"The":[64],"fuses":[69],"features":[72,76],"cell":[74],"line":[75],"at":[77],"bit-wise":[79],"level":[80],"vector-wise":[83],"level.":[84],"We":[85],"demonstrated":[86],"DFFNDDS":[88],"outperforms":[89],"competitive":[90],"methods":[91],"can":[93],"serve":[94],"as":[95],"reliable":[97],"tool":[98]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":35},{"year":2024,"cited_by_count":15},{"year":2023,"cited_by_count":6}],"updated_date":"2026-04-30T09:15:22.047038","created_date":"2025-10-10T00:00:00"}