{"id":"https://openalex.org/W2573972992","doi":"https://doi.org/10.1186/s13321-017-0191-5","title":"S2RSLDB: a comprehensive manually curated, internet-accessible database of the sigma-2 receptor selective ligands","display_name":"S2RSLDB: a comprehensive manually curated, internet-accessible database of the sigma-2 receptor selective ligands","publication_year":2017,"publication_date":"2017-01-21","ids":{"openalex":"https://openalex.org/W2573972992","doi":"https://doi.org/10.1186/s13321-017-0191-5","mag":"2573972992","pmid":"https://pubmed.ncbi.nlm.nih.gov/28123452"},"language":"en","primary_location":{"id":"doi:10.1186/s13321-017-0191-5","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13321-017-0191-5","pdf_url":"https://link.springer.com/content/pdf/10.1186/s13321-017-0191-5.pdf","source":{"id":"https://openalex.org/S180838163","display_name":"Journal of Cheminformatics","issn_l":"1758-2946","issn":["1758-2946"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Cheminformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://link.springer.com/content/pdf/10.1186/s13321-017-0191-5.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5085903667","display_name":"Giovanni Nastasi","orcid":"https://orcid.org/0000-0002-6374-8441"},"institutions":[{"id":"https://openalex.org/I39063666","display_name":"University of Catania","ror":"https://ror.org/03a64bh57","country_code":"IT","type":"education","lineage":["https://openalex.org/I39063666"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Giovanni Nastasi","raw_affiliation_strings":["Department of Drug Sciences, Medicinal Chemistry Section, University of Catania, Viale A. Doria 6, 95125 Catania, Italy","Department of Drug Sciences, Medicinal Chemistry Section, University of Catania, Viale A. Doria 6, 95125, Catania, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Drug Sciences, Medicinal Chemistry Section, University of Catania, Viale A. Doria 6, 95125 Catania, Italy","institution_ids":["https://openalex.org/I39063666"]},{"raw_affiliation_string":"Department of Drug Sciences, Medicinal Chemistry Section, University of Catania, Viale A. Doria 6, 95125, Catania, Italy","institution_ids":["https://openalex.org/I39063666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018861553","display_name":"Carla Miceli","orcid":null},"institutions":[{"id":"https://openalex.org/I39063666","display_name":"University of Catania","ror":"https://ror.org/03a64bh57","country_code":"IT","type":"education","lineage":["https://openalex.org/I39063666"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Carla Miceli","raw_affiliation_strings":["Department of Drug Sciences, Medicinal Chemistry Section, University of Catania, Viale A. Doria 6, 95125 Catania, Italy","Department of Drug Sciences, Medicinal Chemistry Section, University of Catania, Viale A. Doria 6, 95125, Catania, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Drug Sciences, Medicinal Chemistry Section, University of Catania, Viale A. Doria 6, 95125 Catania, Italy","institution_ids":["https://openalex.org/I39063666"]},{"raw_affiliation_string":"Department of Drug Sciences, Medicinal Chemistry Section, University of Catania, Viale A. Doria 6, 95125, Catania, Italy","institution_ids":["https://openalex.org/I39063666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066691562","display_name":"Valeria Pittal\u00e0","orcid":"https://orcid.org/0000-0003-1856-0308"},"institutions":[{"id":"https://openalex.org/I39063666","display_name":"University of Catania","ror":"https://ror.org/03a64bh57","country_code":"IT","type":"education","lineage":["https://openalex.org/I39063666"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Valeria Pittal\u00e0","raw_affiliation_strings":["Department of Drug Sciences, Medicinal Chemistry Section, University of Catania, Viale A. Doria 6, 95125 Catania, Italy","Department of Drug Sciences, Medicinal Chemistry Section, University of Catania, Viale A. Doria 6, 95125, Catania, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Drug Sciences, Medicinal Chemistry Section, University of Catania, Viale A. Doria 6, 95125 Catania, Italy","institution_ids":["https://openalex.org/I39063666"]},{"raw_affiliation_string":"Department of Drug Sciences, Medicinal Chemistry Section, University of Catania, Viale A. Doria 6, 95125, Catania, Italy","institution_ids":["https://openalex.org/I39063666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056771219","display_name":"Maria Modica","orcid":"https://orcid.org/0000-0002-6350-931X"},"institutions":[{"id":"https://openalex.org/I39063666","display_name":"University of Catania","ror":"https://ror.org/03a64bh57","country_code":"IT","type":"education","lineage":["https://openalex.org/I39063666"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Maria N. Modica","raw_affiliation_strings":["Department of Drug Sciences, Medicinal Chemistry Section, University of Catania, Viale A. Doria 6, 95125 Catania, Italy","Department of Drug Sciences, Medicinal Chemistry Section, University of Catania, Viale A. Doria 6, 95125, Catania, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Drug Sciences, Medicinal Chemistry Section, University of Catania, Viale A. Doria 6, 95125 Catania, Italy","institution_ids":["https://openalex.org/I39063666"]},{"raw_affiliation_string":"Department of Drug Sciences, Medicinal Chemistry Section, University of Catania, Viale A. Doria 6, 95125, Catania, Italy","institution_ids":["https://openalex.org/I39063666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056284563","display_name":"Orazio Prezzavento","orcid":"https://orcid.org/0000-0002-3521-264X"},"institutions":[{"id":"https://openalex.org/I39063666","display_name":"University of Catania","ror":"https://ror.org/03a64bh57","country_code":"IT","type":"education","lineage":["https://openalex.org/I39063666"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Orazio Prezzavento","raw_affiliation_strings":["Department of Drug Sciences, Medicinal Chemistry Section, University of Catania, Viale A. Doria 6, 95125 Catania, Italy","Department of Drug Sciences, Medicinal Chemistry Section, University of Catania, Viale A. Doria 6, 95125, Catania, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Drug Sciences, Medicinal Chemistry Section, University of Catania, Viale A. Doria 6, 95125 Catania, Italy","institution_ids":["https://openalex.org/I39063666"]},{"raw_affiliation_string":"Department of Drug Sciences, Medicinal Chemistry Section, University of Catania, Viale A. Doria 6, 95125, Catania, Italy","institution_ids":["https://openalex.org/I39063666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076233600","display_name":"Giuseppe Romeo","orcid":"https://orcid.org/0000-0003-2160-4164"},"institutions":[{"id":"https://openalex.org/I39063666","display_name":"University of Catania","ror":"https://ror.org/03a64bh57","country_code":"IT","type":"education","lineage":["https://openalex.org/I39063666"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Giuseppe Romeo","raw_affiliation_strings":["Department of Drug Sciences, Medicinal Chemistry Section, University of Catania, Viale A. Doria 6, 95125 Catania, Italy","Department of Drug Sciences, Medicinal Chemistry Section, University of Catania, Viale A. Doria 6, 95125, Catania, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Drug Sciences, Medicinal Chemistry Section, University of Catania, Viale A. Doria 6, 95125 Catania, Italy","institution_ids":["https://openalex.org/I39063666"]},{"raw_affiliation_string":"Department of Drug Sciences, Medicinal Chemistry Section, University of Catania, Viale A. Doria 6, 95125, Catania, Italy","institution_ids":["https://openalex.org/I39063666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057685383","display_name":"Antonio Rescifina","orcid":"https://orcid.org/0000-0001-5039-2151"},"institutions":[{"id":"https://openalex.org/I39063666","display_name":"University of Catania","ror":"https://ror.org/03a64bh57","country_code":"IT","type":"education","lineage":["https://openalex.org/I39063666"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Antonio Rescifina","raw_affiliation_strings":["Department of Drug Sciences, Medicinal Chemistry Section, University of Catania, Viale A. Doria 6, 95125 Catania, Italy","Department of Drug Sciences, Medicinal Chemistry Section, University of Catania, Viale A. Doria 6, 95125, Catania, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Drug Sciences, Medicinal Chemistry Section, University of Catania, Viale A. Doria 6, 95125 Catania, Italy","institution_ids":["https://openalex.org/I39063666"]},{"raw_affiliation_string":"Department of Drug Sciences, Medicinal Chemistry Section, University of Catania, Viale A. Doria 6, 95125, Catania, Italy","institution_ids":["https://openalex.org/I39063666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076017923","display_name":"Agostino Marrazzo","orcid":"https://orcid.org/0000-0002-8728-8857"},"institutions":[{"id":"https://openalex.org/I39063666","display_name":"University of Catania","ror":"https://ror.org/03a64bh57","country_code":"IT","type":"education","lineage":["https://openalex.org/I39063666"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Agostino Marrazzo","raw_affiliation_strings":["Department of Drug Sciences, Medicinal Chemistry Section, University of Catania, Viale A. Doria 6, 95125 Catania, Italy","Department of Drug Sciences, Medicinal Chemistry Section, University of Catania, Viale A. Doria 6, 95125, Catania, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Drug Sciences, Medicinal Chemistry Section, University of Catania, Viale A. Doria 6, 95125 Catania, Italy","institution_ids":["https://openalex.org/I39063666"]},{"raw_affiliation_string":"Department of Drug Sciences, Medicinal Chemistry Section, University of Catania, Viale A. Doria 6, 95125, Catania, Italy","institution_ids":["https://openalex.org/I39063666"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5046760541","display_name":"Emanuele Amata","orcid":"https://orcid.org/0000-0002-4750-3479"},"institutions":[{"id":"https://openalex.org/I39063666","display_name":"University of Catania","ror":"https://ror.org/03a64bh57","country_code":"IT","type":"education","lineage":["https://openalex.org/I39063666"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Emanuele Amata","raw_affiliation_strings":["Department of Drug Sciences, Medicinal Chemistry Section, University of Catania, Viale A. Doria 6, 95125 Catania, Italy","Department of Drug Sciences, Medicinal Chemistry Section, University of Catania, Viale A. Doria 6, 95125, Catania, Italy"],"raw_orcid":"https://orcid.org/0000-0002-4750-3479","affiliations":[{"raw_affiliation_string":"Department of Drug Sciences, Medicinal Chemistry Section, University of Catania, Viale A. Doria 6, 95125 Catania, Italy","institution_ids":["https://openalex.org/I39063666"]},{"raw_affiliation_string":"Department of Drug Sciences, Medicinal Chemistry Section, University of Catania, Viale A. Doria 6, 95125, Catania, Italy","institution_ids":["https://openalex.org/I39063666"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5046760541"],"corresponding_institution_ids":["https://openalex.org/I39063666"],"apc_list":{"value":1290,"currency":"GBP","value_usd":1582},"apc_paid":{"value":1290,"currency":"GBP","value_usd":1582},"fwci":2.6921,"has_fulltext":true,"cited_by_count":32,"citation_normalized_percentile":{"value":0.9061463,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":91,"max":99},"biblio":{"volume":"9","issue":"1","first_page":"3","last_page":"3"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13047","display_name":"Pharmacological Receptor Mechanisms and Effects","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T13047","display_name":"Pharmacological Receptor Mechanisms and Effects","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11178","display_name":"Receptor Mechanisms and Signaling","score":0.9936000108718872,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9828000068664551,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6848918795585632},{"id":"https://openalex.org/keywords/the-internet","display_name":"The Internet","score":0.6135457158088684},{"id":"https://openalex.org/keywords/database","display_name":"Database","score":0.5038995146751404},{"id":"https://openalex.org/keywords/world-wide-web","display_name":"World Wide Web","score":0.4874591827392578},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.3785627484321594},{"id":"https://openalex.org/keywords/information-retrieval","display_name":"Information retrieval","score":0.3741549551486969},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.34082406759262085}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6848918795585632},{"id":"https://openalex.org/C110875604","wikidata":"https://www.wikidata.org/wiki/Q75","display_name":"The Internet","level":2,"score":0.6135457158088684},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.5038995146751404},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.4874591827392578},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.3785627484321594},{"id":"https://openalex.org/C23123220","wikidata":"https://www.wikidata.org/wiki/Q816826","display_name":"Information retrieval","level":1,"score":0.3741549551486969},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.34082406759262085}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1186/s13321-017-0191-5","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13321-017-0191-5","pdf_url":"https://link.springer.com/content/pdf/10.1186/s13321-017-0191-5.pdf","source":{"id":"https://openalex.org/S180838163","display_name":"Journal of Cheminformatics","issn_l":"1758-2946","issn":["1758-2946"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Cheminformatics","raw_type":"journal-article"},{"id":"pmid:28123452","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28123452","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of cheminformatics","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:5250622","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5250622","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"J Cheminform","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/s13321-017-0191-5","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13321-017-0191-5","pdf_url":"https://link.springer.com/content/pdf/10.1186/s13321-017-0191-5.pdf","source":{"id":"https://openalex.org/S180838163","display_name":"Journal of Cheminformatics","issn_l":"1758-2946","issn":["1758-2946"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Cheminformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.4399999976158142,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2573972992.pdf","grobid_xml":"https://content.openalex.org/works/W2573972992.grobid-xml"},"referenced_works_count":48,"referenced_works":["https://openalex.org/W641319889","https://openalex.org/W1579542460","https://openalex.org/W1636453461","https://openalex.org/W1802908026","https://openalex.org/W1836780255","https://openalex.org/W1909309034","https://openalex.org/W1966456689","https://openalex.org/W1971409228","https://openalex.org/W1982454833","https://openalex.org/W1992768650","https://openalex.org/W1994224293","https://openalex.org/W2001369831","https://openalex.org/W2002439304","https://openalex.org/W2005265645","https://openalex.org/W2016575780","https://openalex.org/W2019079031","https://openalex.org/W2026692772","https://openalex.org/W2027700076","https://openalex.org/W2029815260","https://openalex.org/W2039274171","https://openalex.org/W2041914114","https://openalex.org/W2044256586","https://openalex.org/W2049538345","https://openalex.org/W2063333882","https://openalex.org/W2082315075","https://openalex.org/W2087563523","https://openalex.org/W2089351812","https://openalex.org/W2103956116","https://openalex.org/W2104722869","https://openalex.org/W2114326383","https://openalex.org/W2120869341","https://openalex.org/W2128167103","https://openalex.org/W2135732933","https://openalex.org/W2151341162","https://openalex.org/W2151697120","https://openalex.org/W2158988264","https://openalex.org/W2169678694","https://openalex.org/W2189803963","https://openalex.org/W2190356450","https://openalex.org/W2290365709","https://openalex.org/W2314811232","https://openalex.org/W2333563571","https://openalex.org/W2408651713","https://openalex.org/W2525804344","https://openalex.org/W2530802742","https://openalex.org/W2752128027","https://openalex.org/W2793129321","https://openalex.org/W4406433889"],"related_works":["https://openalex.org/W2065457896","https://openalex.org/W3173234801","https://openalex.org/W2167984027","https://openalex.org/W3021302227","https://openalex.org/W10630519","https://openalex.org/W1919377569","https://openalex.org/W3144288563","https://openalex.org/W3123907821","https://openalex.org/W2382319620","https://openalex.org/W2164026370"],"abstract_inverted_index":{"Sigma":[0],"(\u03c3)":[1],"receptors":[2],"are":[3,45],"accepted":[4],"as":[5],"a":[6,95,141],"particular":[7],"receptor":[8,21,34,59,70,102,184],"class":[9],"consisting":[10],"of":[11,99,178,182],"two":[12,20],"subtypes:":[13],"sigma-1":[14],"(\u03c31)":[15],"and":[16,29,42,55,65,80,125,139,158,161,187,197,221],"sigma-2":[17,89],"(\u03c32).":[18],"The":[19,32,57,110,130,168,191,224],"subtypes":[22],"have":[23],"specific":[24],"drug":[25],"actions,":[26],"pharmacological":[27,78],"profiles":[28],"molecular":[30],"characteristics.":[31],"\u03c32":[33,58,69,101,183],"is":[35,112,132,172,226],"overexpressed":[36],"in":[37,52,198,217],"several":[38],"tumor":[39,53],"cell":[40],"lines,":[41],"its":[43],"ligands":[44,104,180],"currently":[46],"under":[47],"investigation":[48],"for":[49,165,175],"their":[50],"role":[51],"diagnosis":[54],"treatment.":[56],"structure":[60,116],"has":[61],"not":[62],"been":[63],"disclosed,":[64],"researchers":[66],"rely":[67],"on":[68],"radioligand":[71,118,127],"binding":[72,119,128],"assay":[73],"to":[74,209],"understand":[75],"the":[76,88,100,145,163,176,199,213,218],"receptor\u2019s":[77],"behavior":[79],"design":[81],"new":[82,179],"lead":[83],"compounds.":[84,109],"Here":[85],"we":[86],"present":[87],"Receptor":[90],"Selective":[91],"Ligands":[92],"Database":[93],"(S2RSLDB)":[94],"manually":[96],"curated":[97],"database":[98,111,192,214,225],"selective":[103],"containing":[105],"more":[106],"than":[107],"650":[108],"built":[113],"with":[114,211],"chemical":[115],"information,":[117],"affinity":[120],"data,":[121],"computed":[122],"physicochemical":[123,189],"properties,":[124],"experimental":[126],"procedures.":[129],"S2RSLDB":[131],"freely":[133],"available":[134,208,227],"online":[135,203],"without":[136],"account":[137],"login":[138],"having":[140],"powerful":[142],"search":[143],"engine":[144],"user":[146],"may":[147],"build":[148],"complex":[149],"queries,":[150],"sort":[151],"tabulated":[152],"results,":[153],"generate":[154],"color":[155],"coded":[156],"2D":[157],"3D":[159],"graphs":[160],"download":[162],"data":[164],"additional":[166],"screening.":[167],"collection":[169],"here":[170],"reported":[171],"extremely":[173],"useful":[174],"development":[177],"endowed":[181],"affinity,":[185],"selectivity,":[186],"appropriate":[188],"properties.":[190],"will":[193,206],"be":[194,207],"updated":[195],"yearly":[196],"near":[200],"future,":[201],"an":[202],"submission":[204],"form":[205],"help":[210],"keeping":[212],"widely":[215],"spread":[216],"research":[219],"community":[220],"continually":[222],"updated.":[223],"at":[228],"http://www.researchdsf.unict.it/S2RSLDB":[229],".":[230]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":2},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":12}],"updated_date":"2026-06-19T15:47:20.252518","created_date":"2017-01-26T00:00:00"}