{"id":"https://openalex.org/W4282919091","doi":"https://doi.org/10.1186/s13040-022-00297-8","title":"Single_cell_GRN: gene regulatory network identification based on supervised learning method and Single-cell RNA-seq data","display_name":"Single_cell_GRN: gene regulatory network identification based on supervised learning method and Single-cell RNA-seq data","publication_year":2022,"publication_date":"2022-06-11","ids":{"openalex":"https://openalex.org/W4282919091","doi":"https://doi.org/10.1186/s13040-022-00297-8","pmid":"https://pubmed.ncbi.nlm.nih.gov/35690842"},"language":"en","primary_location":{"id":"doi:10.1186/s13040-022-00297-8","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13040-022-00297-8","pdf_url":"https://biodatamining.biomedcentral.com/counter/pdf/10.1186/s13040-022-00297-8","source":{"id":"https://openalex.org/S84409260","display_name":"BioData Mining","issn_l":"1756-0381","issn":["1756-0381"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BioData Mining","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://biodatamining.biomedcentral.com/counter/pdf/10.1186/s13040-022-00297-8","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5007584947","display_name":"Bin Yang","orcid":"https://orcid.org/0000-0001-6879-7069"},"institutions":[{"id":"https://openalex.org/I4210159676","display_name":"Zaozhuang University","ror":"https://ror.org/05x21tp94","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210159676"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Bin Yang","raw_affiliation_strings":["School of Information Science and Engineering, Zaozhuang University, Zaozhuang, 277160, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Information Science and Engineering, Zaozhuang University, Zaozhuang, 277160, China","institution_ids":["https://openalex.org/I4210159676"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030950144","display_name":"Wenzheng Bao","orcid":"https://orcid.org/0000-0002-1471-5432"},"institutions":[{"id":"https://openalex.org/I124841900","display_name":"Xuzhou University of Technology","ror":"https://ror.org/02315by94","country_code":"CN","type":"education","lineage":["https://openalex.org/I124841900"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Wenzheng Bao","raw_affiliation_strings":["School of Information and Electrical Engineering, Xuzhou University of Technology, Xuzhou, 221018, China. baowz55555@126.com","School of Information and Electrical Engineering, Xuzhou University of Technology, Xuzhou, 221018, China"],"raw_orcid":"https://orcid.org/0000-0002-1471-5432","affiliations":[{"raw_affiliation_string":"School of Information and Electrical Engineering, Xuzhou University of Technology, Xuzhou, 221018, China. baowz55555@126.com","institution_ids":["https://openalex.org/I124841900"]},{"raw_affiliation_string":"School of Information and Electrical Engineering, Xuzhou University of Technology, Xuzhou, 221018, China","institution_ids":["https://openalex.org/I124841900"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101653460","display_name":"Baitong Chen","orcid":"https://orcid.org/0000-0002-1470-7272"},"institutions":[{"id":"https://openalex.org/I177388780","display_name":"Xuzhou Medical College","ror":"https://ror.org/04fe7hy80","country_code":"CN","type":"education","lineage":["https://openalex.org/I177388780"]},{"id":"https://openalex.org/I4210143072","display_name":"Xuzhou No.1 People's Hospital","ror":"https://ror.org/05ca6eb43","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210143072"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Baitong Chen","raw_affiliation_strings":["Xuzhou First People's Hospital, Xuzhou, 221000, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Xuzhou First People's Hospital, Xuzhou, 221000, China","institution_ids":["https://openalex.org/I177388780","https://openalex.org/I4210143072"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5080985245","display_name":"Dan Song","orcid":null},"institutions":[{"id":"https://openalex.org/I4210159676","display_name":"Zaozhuang University","ror":"https://ror.org/05x21tp94","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210159676"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Dan Song","raw_affiliation_strings":["School of Information Science and Engineering, Zaozhuang University, Zaozhuang, 277160, China. songdan@uzz.edu.cn","School of Information Science and Engineering, Zaozhuang University, Zaozhuang, 277160, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Information Science and Engineering, Zaozhuang University, Zaozhuang, 277160, China. songdan@uzz.edu.cn","institution_ids":["https://openalex.org/I4210159676"]},{"raw_affiliation_string":"School of Information Science and Engineering, Zaozhuang University, Zaozhuang, 277160, China","institution_ids":["https://openalex.org/I4210159676"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5030950144","https://openalex.org/A5080985245"],"corresponding_institution_ids":["https://openalex.org/I124841900","https://openalex.org/I4210159676"],"apc_list":{"value":2490,"currency":"USD","value_usd":2490},"apc_paid":{"value":2490,"currency":"USD","value_usd":2490},"fwci":0.9397,"has_fulltext":true,"cited_by_count":13,"citation_normalized_percentile":{"value":0.71931485,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":98},"biblio":{"volume":"15","issue":"1","first_page":"13","last_page":"13"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11289","display_name":"Single-cell and spatial transcriptomics","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11289","display_name":"Single-cell and spatial transcriptomics","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9952999949455261,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12676","display_name":"Machine Learning and ELM","score":0.9882000088691711,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/support-vector-machine","display_name":"Support vector machine","score":0.698528528213501},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6948410272598267},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.651067852973938},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.4957345426082611},{"id":"https://openalex.org/keywords/kernel","display_name":"Kernel (algebra)","score":0.4641742706298828},{"id":"https://openalex.org/keywords/identification","display_name":"Identification (biology)","score":0.4539501368999481},{"id":"https://openalex.org/keywords/random-forest","display_name":"Random forest","score":0.43546563386917114},{"id":"https://openalex.org/keywords/gene-regulatory-network","display_name":"Gene regulatory network","score":0.43462955951690674},{"id":"https://openalex.org/keywords/bayesian-network","display_name":"Bayesian network","score":0.43080925941467285},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.39575523138046265},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.3788551390171051},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.368926465511322},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.24694383144378662},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.20242226123809814},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.18064215779304504},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.1573161780834198}],"concepts":[{"id":"https://openalex.org/C12267149","wikidata":"https://www.wikidata.org/wiki/Q282453","display_name":"Support vector machine","level":2,"score":0.698528528213501},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6948410272598267},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.651067852973938},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.4957345426082611},{"id":"https://openalex.org/C74193536","wikidata":"https://www.wikidata.org/wiki/Q574844","display_name":"Kernel (algebra)","level":2,"score":0.4641742706298828},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.4539501368999481},{"id":"https://openalex.org/C169258074","wikidata":"https://www.wikidata.org/wiki/Q245748","display_name":"Random forest","level":2,"score":0.43546563386917114},{"id":"https://openalex.org/C67339327","wikidata":"https://www.wikidata.org/wiki/Q1502576","display_name":"Gene regulatory network","level":4,"score":0.43462955951690674},{"id":"https://openalex.org/C33724603","wikidata":"https://www.wikidata.org/wiki/Q812540","display_name":"Bayesian network","level":2,"score":0.43080925941467285},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.39575523138046265},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.3788551390171051},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.368926465511322},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.24694383144378662},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.20242226123809814},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.18064215779304504},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1573161780834198},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0},{"id":"https://openalex.org/C114614502","wikidata":"https://www.wikidata.org/wiki/Q76592","display_name":"Combinatorics","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1186/s13040-022-00297-8","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13040-022-00297-8","pdf_url":"https://biodatamining.biomedcentral.com/counter/pdf/10.1186/s13040-022-00297-8","source":{"id":"https://openalex.org/S84409260","display_name":"BioData Mining","issn_l":"1756-0381","issn":["1756-0381"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BioData Mining","raw_type":"journal-article"},{"id":"pmid:35690842","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35690842","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BioData mining","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:9188720","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9188720","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BioData Min","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:b0e4466e9cc44f44ba652eda6ffda528","is_oa":true,"landing_page_url":"https://doaj.org/article/b0e4466e9cc44f44ba652eda6ffda528","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BioData Mining, Vol 15, Iss 1, Pp 1-18 (2022)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/s13040-022-00297-8","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13040-022-00297-8","pdf_url":"https://biodatamining.biomedcentral.com/counter/pdf/10.1186/s13040-022-00297-8","source":{"id":"https://openalex.org/S84409260","display_name":"BioData Mining","issn_l":"1756-0381","issn":["1756-0381"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BioData Mining","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.4699999988079071,"id":"https://metadata.un.org/sdg/15","display_name":"Life in Land"}],"awards":[{"id":"https://openalex.org/G1181396804","display_name":null,"funder_award_id":"KC21047","funder_id":"https://openalex.org/F4320335787","funder_display_name":"Fundamental Research Funds for the Central Universities"},{"id":"https://openalex.org/G1252881154","display_name":null,"funder_award_id":"KC21047","funder_id":"https://openalex.org/F4320324174","funder_display_name":"Natural Science Foundation of Shandong Province"},{"id":"https://openalex.org/G1674435247","display_name":null,"funder_award_id":"2020QN89","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G1827607658","display_name":null,"funder_award_id":"2020QN89","funder_id":"https://openalex.org/F4320325428","funder_display_name":"Zaozhuang University"},{"id":"https://openalex.org/G1960257377","display_name":null,"funder_award_id":"19KJB520016","funder_id":"https://openalex.org/F4320324174","funder_display_name":"Natural Science Foundation of Shandong Province"},{"id":"https://openalex.org/G2030464069","display_name":null,"funder_award_id":"SBK2019040953","funder_id":"https://openalex.org/F4320334982","funder_display_name":"Basic Research Program of Jiangsu Province"},{"id":"https://openalex.org/G2117159217","display_name":null,"funder_award_id":"SBK2019040953","funder_id":"https://openalex.org/F4320322769","funder_display_name":"Natural Science Foundation of Jiangsu Province"},{"id":"https://openalex.org/G2692102211","display_name":null,"funder_award_id":"61902337","funder_id":"https://openalex.org/F4320322769","funder_display_name":"Natural Science Foundation of Jiangsu Province"},{"id":"https://openalex.org/G2746719638","display_name":null,"funder_award_id":"KC21047","funder_id":"https://openalex.org/F4320336657","funder_display_name":"Xuzhou Science and Technology Program"},{"id":"https://openalex.org/G2911789361","display_name":null,"funder_award_id":"19KJB520016","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G3417863741","display_name":null,"funder_award_id":"19KJB520016","funder_id":"https://openalex.org/F4320325428","funder_display_name":"Zaozhuang University"},{"id":"https://openalex.org/G3454202220","display_name":null,"funder_award_id":"KC19142","funder_id":"https://openalex.org/F4320336657","funder_display_name":"Xuzhou Science and Technology Program"},{"id":"https://openalex.org/G368454410","display_name":null,"funder_award_id":"KC19142","funder_id":"https://openalex.org/F4320324174","funder_display_name":"Natural Science Foundation of Shandong Province"},{"id":"https://openalex.org/G3738077157","display_name":null,"funder_award_id":"ZR2015PF007","funder_id":"https://openalex.org/F4320336657","funder_display_name":"Xuzhou Science and Technology Program"},{"id":"https://openalex.org/G3999647555","display_name":null,"funder_award_id":"61902337","funder_id":"https://openalex.org/F4320325428","funder_display_name":"Zaozhuang University"},{"id":"https://openalex.org/G4163428730","display_name":null,"funder_award_id":"KC21047","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G4212843660","display_name":null,"funder_award_id":"19KJB520016","funder_id":"https://openalex.org/F4320322769","funder_display_name":"Natural Science Foundation of Jiangsu Province"},{"id":"https://openalex.org/G4339219020","display_name":null,"funder_award_id":"61902337","funder_id":"https://openalex.org/F4320336657","funder_display_name":"Xuzhou Science and Technology Program"},{"id":"https://openalex.org/G4566069544","display_name":null,"funder_award_id":"ZR2015PF007","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G4734858189","display_name":null,"funder_award_id":"SBK2019040953","funder_id":"https://openalex.org/F4320324174","funder_display_name":"Natural Science Foundation of Shandong Province"},{"id":"https://openalex.org/G4776171345","display_name":null,"funder_award_id":"ZR2015PF007","funder_id":"https://openalex.org/F4320324174","funder_display_name":"Natural Science Foundation of Shandong Province"},{"id":"https://openalex.org/G4897495594","display_name":null,"funder_award_id":"19KJB520016","funder_id":"https://openalex.org/F4320335787","funder_display_name":"Fundamental Research Funds for the Central Universities"},{"id":"https://openalex.org/G4904073147","display_name":null,"funder_award_id":"SBK2019040953","funder_id":"https://openalex.org/F4320335787","funder_display_name":"Fundamental Research Funds for the Central Universities"},{"id":"https://openalex.org/G4909321860","display_name":null,"funder_award_id":"19KJB520016","funder_id":"https://openalex.org/F4320336657","funder_display_name":"Xuzhou Science and Technology Program"},{"id":"https://openalex.org/G5188405506","display_name":null,"funder_award_id":"SBK2019040953","funder_id":"https://openalex.org/F4320325428","funder_display_name":"Zaozhuang University"},{"id":"https://openalex.org/G5195581150","display_name":null,"funder_award_id":"KC19142","funder_id":"https://openalex.org/F4320335787","funder_display_name":"Fundamental Research Funds for the Central Universities"},{"id":"https://openalex.org/G5249750224","display_name":null,"funder_award_id":"2020QN89","funder_id":"https://openalex.org/F4320336657","funder_display_name":"Xuzhou Science and Technology Program"},{"id":"https://openalex.org/G5738802583","display_name":null,"funder_award_id":"2020QN89","funder_id":"https://openalex.org/F4320322769","funder_display_name":"Natural Science Foundation of Jiangsu Province"},{"id":"https://openalex.org/G621676200","display_name":null,"funder_award_id":"61902337","funder_id":"https://openalex.org/F4320335787","funder_display_name":"Fundamental Research Funds for the Central Universities"},{"id":"https://openalex.org/G6354098474","display_name":null,"funder_award_id":"KC21047","funder_id":"https://openalex.org/F4320325428","funder_display_name":"Zaozhuang University"},{"id":"https://openalex.org/G6358345890","display_name":null,"funder_award_id":"2020QN89","funder_id":"https://openalex.org/F4320324174","funder_display_name":"Natural Science Foundation of Shandong Province"},{"id":"https://openalex.org/G6443413637","display_name":null,"funder_award_id":"SBK2019040953","funder_id":"https://openalex.org/F4320336657","funder_display_name":"Xuzhou Science and Technology Program"},{"id":"https://openalex.org/G6464639837","display_name":null,"funder_award_id":"ZR2015PF007","funder_id":"https://openalex.org/F4320335787","funder_display_name":"Fundamental Research Funds for the Central Universities"},{"id":"https://openalex.org/G7134451153","display_name":null,"funder_award_id":"61,902,337","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G717186993","display_name":null,"funder_award_id":"KC19142","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7187343147","display_name":null,"funder_award_id":"61902337","funder_id":"https://openalex.org/F4320324174","funder_display_name":"Natural Science Foundation of Shandong Province"},{"id":"https://openalex.org/G7447923291","display_name":null,"funder_award_id":"SBK2019040953","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7527818666","display_name":null,"funder_award_id":"ZR2015PF007","funder_id":"https://openalex.org/F4320322769","funder_display_name":"Natural Science Foundation of Jiangsu Province"},{"id":"https://openalex.org/G7772602906","display_name":null,"funder_award_id":"KC19142","funder_id":"https://openalex.org/F4320322769","funder_display_name":"Natural Science Foundation of Jiangsu Province"},{"id":"https://openalex.org/G7917009979","display_name":null,"funder_award_id":"ZR2015PF007","funder_id":"https://openalex.org/F4320325428","funder_display_name":"Zaozhuang University"},{"id":"https://openalex.org/G8146059967","display_name":null,"funder_award_id":"2020QN89","funder_id":"https://openalex.org/F4320335787","funder_display_name":"Fundamental Research Funds for the Central Universities"},{"id":"https://openalex.org/G8270283117","display_name":null,"funder_award_id":"KC21047","funder_id":"https://openalex.org/F4320322769","funder_display_name":"Natural Science Foundation of Jiangsu Province"},{"id":"https://openalex.org/G8665469106","display_name":null,"funder_award_id":"KC19142","funder_id":"https://openalex.org/F4320325428","funder_display_name":"Zaozhuang University"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320321605","display_name":"Government of Jiangsu Province","ror":"https://ror.org/004svx814"},{"id":"https://openalex.org/F4320322769","display_name":"Natural Science Foundation of Jiangsu Province","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320324174","display_name":"Natural Science Foundation of Shandong Province","ror":null},{"id":"https://openalex.org/F4320325428","display_name":"Zaozhuang University","ror":"https://ror.org/05x21tp94"},{"id":"https://openalex.org/F4320334982","display_name":"Basic Research Program of Jiangsu Province","ror":null},{"id":"https://openalex.org/F4320335787","display_name":"Fundamental Research Funds for the Central Universities","ror":null},{"id":"https://openalex.org/F4320336657","display_name":"Xuzhou Science and Technology Program","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4282919091.pdf","grobid_xml":"https://content.openalex.org/works/W4282919091.grobid-xml"},"referenced_works_count":51,"referenced_works":["https://openalex.org/W1485123848","https://openalex.org/W1594730842","https://openalex.org/W1969959732","https://openalex.org/W1979283544","https://openalex.org/W1988917080","https://openalex.org/W2000132404","https://openalex.org/W2032170121","https://openalex.org/W2039065483","https://openalex.org/W2040297641","https://openalex.org/W2068881679","https://openalex.org/W2073286325","https://openalex.org/W2084942072","https://openalex.org/W2101029276","https://openalex.org/W2101711129","https://openalex.org/W2125283600","https://openalex.org/W2132424470","https://openalex.org/W2136571107","https://openalex.org/W2143426320","https://openalex.org/W2143502890","https://openalex.org/W2143826137","https://openalex.org/W2160095931","https://openalex.org/W2165073978","https://openalex.org/W2169053773","https://openalex.org/W2258406303","https://openalex.org/W2416402039","https://openalex.org/W2484878711","https://openalex.org/W2493614923","https://openalex.org/W2498119267","https://openalex.org/W2501885762","https://openalex.org/W2511896561","https://openalex.org/W2523825305","https://openalex.org/W2616922646","https://openalex.org/W2623843598","https://openalex.org/W2757234574","https://openalex.org/W2787178215","https://openalex.org/W2789914388","https://openalex.org/W2792357126","https://openalex.org/W2794821752","https://openalex.org/W2794956775","https://openalex.org/W2799123729","https://openalex.org/W2807587036","https://openalex.org/W2886793380","https://openalex.org/W2889751329","https://openalex.org/W2903866590","https://openalex.org/W2911964244","https://openalex.org/W2951850020","https://openalex.org/W2952535935","https://openalex.org/W2962329643","https://openalex.org/W2964992537","https://openalex.org/W2975536174","https://openalex.org/W3023943971"],"related_works":["https://openalex.org/W3193043704","https://openalex.org/W4386259002","https://openalex.org/W1546989560","https://openalex.org/W3171520305","https://openalex.org/W1924178503","https://openalex.org/W4396689146","https://openalex.org/W4200112873","https://openalex.org/W2955796858","https://openalex.org/W2004826645","https://openalex.org/W2349909726"],"abstract_inverted_index":{"Single-cell":[0],"RNA-seq":[1,53,98,119,181],"overcomes":[2],"the":[3,18,31,60,89,162],"shortcomings":[4],"of":[5,21,33,62,93,155],"conventional":[6],"transcriptome":[7,19],"sequencing":[8],"technology":[9],"and":[10,28,83,109,123,144,159,172],"could":[11],"provide":[12],"a":[13],"powerful":[14],"tool":[15],"for":[16,87],"distinguishing":[17],"characteristics":[20],"various":[22],"cell":[23],"types":[24],"in":[25,132,153],"biological":[26],"tissues,":[27],"comprehensively":[29],"revealing":[30],"heterogeneity":[32],"gene":[34,47],"expression":[35],"between":[36],"cells.":[37],"Many":[38],"Intelligent":[39],"Computing":[40],"methods":[41,137],"have":[42,161],"been":[43],"presented":[44],"to":[45,178],"infer":[46],"regulatory":[48],"network":[49],"(GRN)":[50],"with":[51,96],"single-cell":[52,97,118,180],"data.":[54,182],"In":[55,101,169],"this":[56],"paper,":[57],"we":[58],"investigate":[59],"performances":[61,164],"seven":[63],"classifiers":[64],"including":[65],"support":[66],"vector":[67],"machine":[68],"(SVM),":[69],"random":[70],"forest":[71],"(RF),":[72],"Naive":[73],"Bayesian":[74],"(NB),":[75],"GBDT,":[76,141],"logical":[77],"regression":[78],"(LR),":[79],"decision":[80],"tree":[81],"(DT)":[82],"K-Nearest":[84],"Neighbor":[85],"(KNN)":[86],"solving":[88],"binary":[90],"classification":[91],"problems":[92],"GRN":[94],"inference":[95],"data":[99],"(Single_cell_GRN).":[100],"SVM,":[102,157,170],"three":[103],"different":[104],"kernel":[105],"functions":[106],"(linear,":[107],"polynomial":[108,173],"radial":[110],"basis":[111],"function)":[112],"are":[113,125,175],"utilized,":[114],"respectively.":[115],"Three":[116],"real":[117],"datasets":[120],"from":[121],"mouse":[122],"human":[124],"utilized.":[126],"The":[127],"experiment":[128],"results":[129],"prove":[130],"that":[131],"most":[133],"cases":[134],"supervised":[135],"learning":[136,150],"(SVM,":[138],"RF,":[139],"NB,":[140],"LR,":[142],"DT":[143],"KNN)":[145],"perform":[146],"better":[147,163],"than":[148,165],"unsupervised":[149],"method":[151],"(GENIE3)":[152],"terms":[154],"AUC.":[156],"RF":[158],"KNN":[160],"other":[166],"four":[167],"classifiers.":[168],"linear":[171],"kernels":[174],"more":[176],"fit":[177],"model":[179]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":2}],"updated_date":"2026-08-11T07:18:39.950985","created_date":"2025-10-10T00:00:00"}