{"id":"https://openalex.org/W4206076329","doi":"https://doi.org/10.1186/s13040-021-00286-3","title":"Polymorphisms in the mTOR-PI3K-Akt pathway, energy balance-related exposures and colorectal cancer risk in the Netherlands Cohort Study","display_name":"Polymorphisms in the mTOR-PI3K-Akt pathway, energy balance-related exposures and colorectal cancer risk in the Netherlands Cohort Study","publication_year":2022,"publication_date":"2022-01-10","ids":{"openalex":"https://openalex.org/W4206076329","doi":"https://doi.org/10.1186/s13040-021-00286-3","pmid":"https://pubmed.ncbi.nlm.nih.gov/35012583"},"language":"en","primary_location":{"id":"doi:10.1186/s13040-021-00286-3","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13040-021-00286-3","pdf_url":"https://biodatamining.biomedcentral.com/counter/pdf/10.1186/s13040-021-00286-3","source":{"id":"https://openalex.org/S84409260","display_name":"BioData Mining","issn_l":"1756-0381","issn":["1756-0381"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BioData Mining","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://biodatamining.biomedcentral.com/counter/pdf/10.1186/s13040-021-00286-3","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5026260709","display_name":"Colinda C.J.M. Simons","orcid":"https://orcid.org/0000-0002-0085-5186"},"institutions":[{"id":"https://openalex.org/I34352273","display_name":"Maastricht University","ror":"https://ror.org/02jz4aj89","country_code":"NL","type":"education","lineage":["https://openalex.org/I34352273"]}],"countries":["NL"],"is_corresponding":true,"raw_author_name":"Colinda C.J.M. Simons","raw_affiliation_strings":["Department of Epidemiology, GROW - School for Oncology and Developmental Biology, Maastricht University, Maastricht, the Netherlands. colinda.simons@maastrichtuniversity.nl","Department of Epidemiology, GROW \u2013 School for Oncology and Developmental Biology, Maastricht University, Maastricht, the Netherlands"],"affiliations":[{"raw_affiliation_string":"Department of Epidemiology, GROW - School for Oncology and Developmental Biology, Maastricht University, Maastricht, the Netherlands. colinda.simons@maastrichtuniversity.nl","institution_ids":[]},{"raw_affiliation_string":"Department of Epidemiology, GROW \u2013 School for Oncology and Developmental Biology, Maastricht University, Maastricht, the Netherlands","institution_ids":["https://openalex.org/I34352273"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090597582","display_name":"Leo J. Schouten","orcid":"https://orcid.org/0000-0003-3361-7560"},"institutions":[{"id":"https://openalex.org/I34352273","display_name":"Maastricht University","ror":"https://ror.org/02jz4aj89","country_code":"NL","type":"education","lineage":["https://openalex.org/I34352273"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Leo J. Schouten","raw_affiliation_strings":["Department of Epidemiology, GROW - School for Oncology and Developmental Biology, Maastricht University, Maastricht, the Netherlands","Department of Epidemiology, GROW \u2013 School for Oncology and Developmental Biology, Maastricht University, Maastricht, the Netherlands"],"affiliations":[{"raw_affiliation_string":"Department of Epidemiology, GROW - School for Oncology and Developmental Biology, Maastricht University, Maastricht, the Netherlands","institution_ids":["https://openalex.org/I34352273"]},{"raw_affiliation_string":"Department of Epidemiology, GROW \u2013 School for Oncology and Developmental Biology, Maastricht University, Maastricht, the Netherlands","institution_ids":["https://openalex.org/I34352273"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014817206","display_name":"Roger Godschalk","orcid":"https://orcid.org/0000-0001-9140-0525"},"institutions":[{"id":"https://openalex.org/I34352273","display_name":"Maastricht University","ror":"https://ror.org/02jz4aj89","country_code":"NL","type":"education","lineage":["https://openalex.org/I34352273"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Roger W.L. Godschalk","raw_affiliation_strings":["Department of Pharmacology and Toxicology, NUTRIM - School for Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht, the Netherlands","Department of Pharmacology and Toxicology, NUTRIM \u2013 School for Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht, the Netherlands"],"affiliations":[{"raw_affiliation_string":"Department of Pharmacology and Toxicology, NUTRIM - School for Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht, the Netherlands","institution_ids":[]},{"raw_affiliation_string":"Department of Pharmacology and Toxicology, NUTRIM \u2013 School for Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht, the Netherlands","institution_ids":["https://openalex.org/I34352273"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038697595","display_name":"Frederik\u2010Jan van Schooten","orcid":"https://orcid.org/0000-0001-8111-8198"},"institutions":[{"id":"https://openalex.org/I34352273","display_name":"Maastricht University","ror":"https://ror.org/02jz4aj89","country_code":"NL","type":"education","lineage":["https://openalex.org/I34352273"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Frederik-Jan van Schooten","raw_affiliation_strings":["Department of Pharmacology and Toxicology, NUTRIM - School for Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht, the Netherlands","Department of Pharmacology and Toxicology, NUTRIM \u2013 School for Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht, the Netherlands"],"affiliations":[{"raw_affiliation_string":"Department of Pharmacology and Toxicology, NUTRIM - School for Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht, the Netherlands","institution_ids":[]},{"raw_affiliation_string":"Department of Pharmacology and Toxicology, NUTRIM \u2013 School for Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht, the Netherlands","institution_ids":["https://openalex.org/I34352273"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063361829","display_name":"Monika Stoll","orcid":"https://orcid.org/0000-0002-2711-4281"},"institutions":[{"id":"https://openalex.org/I22465464","display_name":"University of M\u00fcnster","ror":"https://ror.org/00pd74e08","country_code":"DE","type":"education","lineage":["https://openalex.org/I22465464"]},{"id":"https://openalex.org/I34352273","display_name":"Maastricht University","ror":"https://ror.org/02jz4aj89","country_code":"NL","type":"education","lineage":["https://openalex.org/I34352273"]}],"countries":["DE","NL"],"is_corresponding":false,"raw_author_name":"Monika Stoll","raw_affiliation_strings":["Department of Biochemistry, Maastricht Centre for Systems Biology (MaCSBio), School for Cardiovascular Diseases, CARIM-, Maastricht University, Maastricht, the Netherlands","Institute of Human Genetics, Genetic Epidemiology, University of M\u00fcnster, M\u00fcnster, Germany","Department of Biochemistry, Maastricht Centre for Systems Biology (MaCSBio), School for Cardiovascular Diseases, CARIM\u2013, Maastricht University, Maastricht, the Netherlands"],"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Maastricht Centre for Systems Biology (MaCSBio), School for Cardiovascular Diseases, CARIM-, Maastricht University, Maastricht, the Netherlands","institution_ids":[]},{"raw_affiliation_string":"Institute of Human Genetics, Genetic Epidemiology, University of M\u00fcnster, M\u00fcnster, Germany","institution_ids":["https://openalex.org/I22465464"]},{"raw_affiliation_string":"Department of Biochemistry, Maastricht Centre for Systems Biology (MaCSBio), School for Cardiovascular Diseases, CARIM\u2013, Maastricht University, Maastricht, the Netherlands","institution_ids":["https://openalex.org/I34352273"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051714890","display_name":"Kristel Van Steen","orcid":"https://orcid.org/0000-0001-9868-5033"},"institutions":[{"id":"https://openalex.org/I157674565","display_name":"University of Li\u00e8ge","ror":"https://ror.org/00afp2z80","country_code":"BE","type":"education","lineage":["https://openalex.org/I157674565"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Kristel Van Steen","raw_affiliation_strings":["GIGA-R Medical Genomics - BIO3, University of Li\u00e8ge, Li\u00e8ge, Belgium","GIGA-R Medical Genomics \u2013 BIO3, University of Li\u00e8ge, Li\u00e8ge, Belgium"],"affiliations":[{"raw_affiliation_string":"GIGA-R Medical Genomics - BIO3, University of Li\u00e8ge, Li\u00e8ge, Belgium","institution_ids":[]},{"raw_affiliation_string":"GIGA-R Medical Genomics \u2013 BIO3, University of Li\u00e8ge, Li\u00e8ge, Belgium","institution_ids":["https://openalex.org/I157674565"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001404405","display_name":"Piet A. van den Brandt","orcid":"https://orcid.org/0000-0001-8781-8099"},"institutions":[{"id":"https://openalex.org/I34352273","display_name":"Maastricht University","ror":"https://ror.org/02jz4aj89","country_code":"NL","type":"education","lineage":["https://openalex.org/I34352273"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Piet A. van den Brandt","raw_affiliation_strings":["Department of Epidemiology, GROW - School for Oncology and Developmental Biology, Maastricht University, Maastricht, the Netherlands","Department of Epidemiology, GROW \u2013 School for Oncology and Developmental Biology, Maastricht University, Maastricht, the Netherlands"],"affiliations":[{"raw_affiliation_string":"Department of Epidemiology, GROW - School for Oncology and Developmental Biology, Maastricht University, Maastricht, the Netherlands","institution_ids":["https://openalex.org/I34352273"]},{"raw_affiliation_string":"Department of Epidemiology, GROW \u2013 School for Oncology and Developmental Biology, Maastricht University, Maastricht, the Netherlands","institution_ids":["https://openalex.org/I34352273"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5030743298","display_name":"Matty P. Weijenberg","orcid":"https://orcid.org/0000-0003-1695-4768"},"institutions":[{"id":"https://openalex.org/I34352273","display_name":"Maastricht University","ror":"https://ror.org/02jz4aj89","country_code":"NL","type":"education","lineage":["https://openalex.org/I34352273"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Matty P. Weijenberg","raw_affiliation_strings":["Department of Epidemiology, GROW - School for Oncology and Developmental Biology, Maastricht University, Maastricht, the Netherlands","Department of Epidemiology, GROW \u2013 School for Oncology and Developmental Biology, Maastricht University, Maastricht, the Netherlands"],"affiliations":[{"raw_affiliation_string":"Department of Epidemiology, GROW - School for Oncology and Developmental Biology, Maastricht University, Maastricht, the Netherlands","institution_ids":["https://openalex.org/I34352273"]},{"raw_affiliation_string":"Department of Epidemiology, GROW \u2013 School for Oncology and Developmental Biology, Maastricht University, Maastricht, the Netherlands","institution_ids":["https://openalex.org/I34352273"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5026260709"],"corresponding_institution_ids":["https://openalex.org/I34352273"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2072},"fwci":0.3466,"has_fulltext":true,"cited_by_count":5,"citation_normalized_percentile":{"value":0.53710303,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":99},"biblio":{"volume":"15","issue":"1","first_page":"2","last_page":"2"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10952","display_name":"PI3K/AKT/mTOR signaling in cancer","score":0.9934999942779541,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10952","display_name":"PI3K/AKT/mTOR signaling in cancer","score":0.9934999942779541,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13984","display_name":"Nutrition, Genetics, and Disease","score":0.9700000286102295,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11339","display_name":"Metabolism, Diabetes, and Cancer","score":0.9695000052452087,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pi3k/akt/mtor-pathway","display_name":"PI3K/AKT/mTOR pathway","score":0.7509398460388184},{"id":"https://openalex.org/keywords/colorectal-cancer","display_name":"Colorectal cancer","score":0.6741187572479248},{"id":"https://openalex.org/keywords/cohort","display_name":"Cohort","score":0.5890213847160339},{"id":"https://openalex.org/keywords/protein-kinase-b","display_name":"Protein kinase B","score":0.5222457051277161},{"id":"https://openalex.org/keywords/balance","display_name":"Balance (ability)","score":0.46375396847724915},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.4452120065689087},{"id":"https://openalex.org/keywords/environmental-health","display_name":"Environmental health","score":0.4391133189201355},{"id":"https://openalex.org/keywords/oncology","display_name":"Oncology","score":0.41682565212249756},{"id":"https://openalex.org/keywords/energy-balance","display_name":"Energy balance","score":0.413627028465271},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.38575512170791626},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.34882819652557373},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.23135125637054443},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.22211742401123047},{"id":"https://openalex.org/keywords/signal-transduction","display_name":"Signal transduction","score":0.18729665875434875}],"concepts":[{"id":"https://openalex.org/C86554907","wikidata":"https://www.wikidata.org/wiki/Q285613","display_name":"PI3K/AKT/mTOR pathway","level":3,"score":0.7509398460388184},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.6741187572479248},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.5890213847160339},{"id":"https://openalex.org/C75217442","wikidata":"https://www.wikidata.org/wiki/Q423650","display_name":"Protein kinase B","level":3,"score":0.5222457051277161},{"id":"https://openalex.org/C168031717","wikidata":"https://www.wikidata.org/wiki/Q1530280","display_name":"Balance (ability)","level":2,"score":0.46375396847724915},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4452120065689087},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.4391133189201355},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.41682565212249756},{"id":"https://openalex.org/C2777423268","wikidata":"https://www.wikidata.org/wiki/Q3663116","display_name":"Energy balance","level":2,"score":0.413627028465271},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.38575512170791626},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.34882819652557373},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.23135125637054443},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.22211742401123047},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.18729665875434875},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.0},{"id":"https://openalex.org/C99508421","wikidata":"https://www.wikidata.org/wiki/Q2678675","display_name":"Physical medicine and rehabilitation","level":1,"score":0.0}],"mesh":[],"locations_count":7,"locations":[{"id":"doi:10.1186/s13040-021-00286-3","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13040-021-00286-3","pdf_url":"https://biodatamining.biomedcentral.com/counter/pdf/10.1186/s13040-021-00286-3","source":{"id":"https://openalex.org/S84409260","display_name":"BioData Mining","issn_l":"1756-0381","issn":["1756-0381"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BioData Mining","raw_type":"journal-article"},{"id":"pmid:35012583","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35012583","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BioData mining","raw_type":null},{"id":"pmh:oai:cris.maastrichtuniversity.nl:openaire/9dfbf2a6-2721-4663-b6eb-5f75a4c70d81","is_oa":true,"landing_page_url":"https://cris.maastrichtuniversity.nl/en/publications/9dfbf2a6-2721-4663-b6eb-5f75a4c70d81","pdf_url":null,"source":{"id":"https://openalex.org/S4306402616","display_name":"Research Publications (Maastricht University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I34352273","host_organization_name":"Maastricht University","host_organization_lineage":["https://openalex.org/I34352273"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Simons, C C J M, Schouten, L J, Godschalk, R W L, Van Schooten, F J, Stoll, M, Van Steen, K, van den Brandt, P A & Weijenberg, M P 2022, 'Polymorphisms in the mTOR-PI3K-Akt pathway, energy balance-related exposures and colorectal cancer risk in the Netherlands Cohort Study', Biodata Mining, vol. 15, no. 1, 2. https://doi.org/10.1186/s13040-021-00286-3","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"pmh:oai:lirias2repo.kuleuven.be:20.500.12942/722007","is_oa":true,"landing_page_url":"https://lirias.kuleuven.be/handle/20.500.12942/722007","pdf_url":null,"source":{"id":"https://openalex.org/S7407055369","display_name":"Lirias","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Biodata Mining, vol. 15 (1), Art.No. ARTN 2","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"pmh:oai:doaj.org/article:2c838d2530a6442893a79d5f3516e9ca","is_oa":true,"landing_page_url":"https://doaj.org/article/2c838d2530a6442893a79d5f3516e9ca","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BioData Mining, Vol 15, Iss 1, Pp 1-20 (2022)","raw_type":"article"},{"id":"pmh:oai:orbi.ulg.ac.be:2268/291730","is_oa":true,"landing_page_url":"https://orbi.uliege.be/handle/2268/291730","pdf_url":null,"source":{"id":"https://openalex.org/S4306400651","display_name":"Open Repository and Bibliography (University of Li\u00e8ge)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I157674565","host_organization_name":"University of Li\u00e8ge","host_organization_lineage":["https://openalex.org/I157674565"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BioData Mining, 15 (1), 1-20 (2022)","raw_type":"peer reviewed"},{"id":"pmh:oai:pubmedcentral.nih.gov:8751328","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8751328","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BioData Min","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/s13040-021-00286-3","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13040-021-00286-3","pdf_url":"https://biodatamining.biomedcentral.com/counter/pdf/10.1186/s13040-021-00286-3","source":{"id":"https://openalex.org/S84409260","display_name":"BioData Mining","issn_l":"1756-0381","issn":["1756-0381"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BioData Mining","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G4208386340","display_name":null,"funder_award_id":"health foundation limburg","funder_id":"https://openalex.org/F4320316459","funder_display_name":"Health Foundation Limburg"},{"id":"https://openalex.org/G5749298763","display_name":null,"funder_award_id":"2012/618","funder_id":"https://openalex.org/F4320334633","funder_display_name":"World Cancer Research Fund"},{"id":"https://openalex.org/G7134434276","display_name":null,"funder_award_id":"2013/673","funder_id":"https://openalex.org/F4320334633","funder_display_name":"World Cancer Research Fund"}],"funders":[{"id":"https://openalex.org/F4320316459","display_name":"Health Foundation Limburg","ror":null},{"id":"https://openalex.org/F4320334633","display_name":"World Cancer Research Fund","ror":"https://ror.org/02gc7qc02"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4206076329.pdf","grobid_xml":"https://content.openalex.org/works/W4206076329.grobid-xml"},"referenced_works_count":49,"referenced_works":["https://openalex.org/W1523693806","https://openalex.org/W1580835424","https://openalex.org/W1829421051","https://openalex.org/W1942246373","https://openalex.org/W1953155253","https://openalex.org/W1965151472","https://openalex.org/W1992005334","https://openalex.org/W1995399604","https://openalex.org/W1995962039","https://openalex.org/W1999875590","https://openalex.org/W2006559495","https://openalex.org/W2013355610","https://openalex.org/W2016317262","https://openalex.org/W2020626619","https://openalex.org/W2061745177","https://openalex.org/W2064588310","https://openalex.org/W2068906539","https://openalex.org/W2077048418","https://openalex.org/W2107138005","https://openalex.org/W2107315098","https://openalex.org/W2109856365","https://openalex.org/W2111839101","https://openalex.org/W2117692326","https://openalex.org/W2119652769","https://openalex.org/W2121070670","https://openalex.org/W2122410197","https://openalex.org/W2133387465","https://openalex.org/W2134083177","https://openalex.org/W2134510309","https://openalex.org/W2138412263","https://openalex.org/W2139852278","https://openalex.org/W2145025818","https://openalex.org/W2145391067","https://openalex.org/W2146785268","https://openalex.org/W2148038983","https://openalex.org/W2150623476","https://openalex.org/W2151424599","https://openalex.org/W2153607816","https://openalex.org/W2154069478","https://openalex.org/W2154608501","https://openalex.org/W2155635136","https://openalex.org/W2161998322","https://openalex.org/W2409951388","https://openalex.org/W2415094114","https://openalex.org/W2423934572","https://openalex.org/W2503101787","https://openalex.org/W2516293782","https://openalex.org/W2528167274","https://openalex.org/W3038129077"],"related_works":["https://openalex.org/W3183179750","https://openalex.org/W2024933597","https://openalex.org/W2070783513","https://openalex.org/W3116479654","https://openalex.org/W4205189596","https://openalex.org/W2916964185","https://openalex.org/W2422815049","https://openalex.org/W2098584395","https://openalex.org/W2982360817","https://openalex.org/W4206939639"],"abstract_inverted_index":{"Current":[0],"data":[1],"suggest":[2],"that":[3],"the":[4,30],"mTOR-PI3K-Akt":[5,31],"pathway":[6],"may":[7],"be":[8],"involved":[9],"in":[10,29],"colon":[11,21],"cancer":[12,22],"development.":[13],"This":[14],"study":[15],"thereby":[16],"sheds":[17],"more":[18],"light":[19],"on":[20],"etiology":[23],"through":[24],"use":[25],"of":[26],"genetic":[27],"variation":[28],"pathway.":[32]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2023,"cited_by_count":4}],"updated_date":"2026-03-20T23:20:44.827607","created_date":"2025-10-10T00:00:00"}