{"id":"https://openalex.org/W2587099845","doi":"https://doi.org/10.1186/s13040-017-0123-y","title":"Semantics-based plausible reasoning to extend the knowledge coverage of medical knowledge bases for improved clinical decision support","display_name":"Semantics-based plausible reasoning to extend the knowledge coverage of medical knowledge bases for improved clinical decision support","publication_year":2017,"publication_date":"2017-02-10","ids":{"openalex":"https://openalex.org/W2587099845","doi":"https://doi.org/10.1186/s13040-017-0123-y","mag":"2587099845"},"language":"en","primary_location":{"id":"doi:10.1186/s13040-017-0123-y","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13040-017-0123-y","pdf_url":"https://biodatamining.biomedcentral.com/track/pdf/10.1186/s13040-017-0123-y","source":{"id":"https://openalex.org/S84409260","display_name":"BioData Mining","issn_l":"1756-0381","issn":["1756-0381"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BioData Mining","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://biodatamining.biomedcentral.com/track/pdf/10.1186/s13040-017-0123-y","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5034208509","display_name":"Hossein Mohammadhassanzadeh","orcid":"https://orcid.org/0000-0002-1922-0455"},"institutions":[{"id":"https://openalex.org/I129902397","display_name":"Dalhousie University","ror":"https://ror.org/01e6qks80","country_code":"CA","type":"education","lineage":["https://openalex.org/I129902397"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"Hossein Mohammadhassanzadeh","raw_affiliation_strings":["NICHE Research Group, Faculty of Computer Science, Dalhousie University, Halifax, NS, B3H4R2, Canada"],"affiliations":[{"raw_affiliation_string":"NICHE Research Group, Faculty of Computer Science, Dalhousie University, Halifax, NS, B3H4R2, Canada","institution_ids":["https://openalex.org/I129902397"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005125860","display_name":"William Van Woensel","orcid":"https://orcid.org/0000-0002-7049-8735"},"institutions":[{"id":"https://openalex.org/I129902397","display_name":"Dalhousie University","ror":"https://ror.org/01e6qks80","country_code":"CA","type":"education","lineage":["https://openalex.org/I129902397"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"William Van Woensel","raw_affiliation_strings":["NICHE Research Group, Faculty of Computer Science, Dalhousie University, Halifax, NS, B3H4R2, Canada"],"affiliations":[{"raw_affiliation_string":"NICHE Research Group, Faculty of Computer Science, Dalhousie University, Halifax, NS, B3H4R2, Canada","institution_ids":["https://openalex.org/I129902397"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023659508","display_name":"Samina Abidi","orcid":"https://orcid.org/0000-0002-7805-6122"},"institutions":[{"id":"https://openalex.org/I129902397","display_name":"Dalhousie University","ror":"https://ror.org/01e6qks80","country_code":"CA","type":"education","lineage":["https://openalex.org/I129902397"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Samina Raza Abidi","raw_affiliation_strings":["Medical Informatics, Faculty of Medicine, Dalhousie University, Halifax, NS, B3H4R2, Canada","NICHE Research Group, Faculty of Computer Science, Dalhousie University, Halifax, NS, B3H4R2, Canada"],"affiliations":[{"raw_affiliation_string":"Medical Informatics, Faculty of Medicine, Dalhousie University, Halifax, NS, B3H4R2, Canada","institution_ids":["https://openalex.org/I129902397"]},{"raw_affiliation_string":"NICHE Research Group, Faculty of Computer Science, Dalhousie University, Halifax, NS, B3H4R2, Canada","institution_ids":["https://openalex.org/I129902397"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5058424348","display_name":"Syed Sibte Raza Abidi","orcid":"https://orcid.org/0000-0003-3075-7736"},"institutions":[{"id":"https://openalex.org/I129902397","display_name":"Dalhousie University","ror":"https://ror.org/01e6qks80","country_code":"CA","type":"education","lineage":["https://openalex.org/I129902397"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Syed Sibte Raza Abidi","raw_affiliation_strings":["Medical Informatics, Faculty of Medicine, Dalhousie University, Halifax, NS, B3H4R2, Canada","NICHE Research Group, Faculty of Computer Science, Dalhousie University, Halifax, NS, B3H4R2, Canada"],"affiliations":[{"raw_affiliation_string":"Medical Informatics, Faculty of Medicine, Dalhousie University, Halifax, NS, B3H4R2, Canada","institution_ids":["https://openalex.org/I129902397"]},{"raw_affiliation_string":"NICHE Research Group, Faculty of Computer Science, Dalhousie University, Halifax, NS, B3H4R2, Canada","institution_ids":["https://openalex.org/I129902397"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5034208509"],"corresponding_institution_ids":["https://openalex.org/I129902397"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2072},"fwci":0.8952,"has_fulltext":true,"cited_by_count":20,"citation_normalized_percentile":{"value":0.72701792,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"10","issue":"1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11710","display_name":"Biomedical Text Mining and Ontologies","score":0.9991000294685364,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11710","display_name":"Biomedical Text Mining and Ontologies","score":0.9991000294685364,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10215","display_name":"Semantic Web and Ontologies","score":0.9987000226974487,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10028","display_name":"Topic Modeling","score":0.9965000152587891,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7392696738243103},{"id":"https://openalex.org/keywords/model-based-reasoning","display_name":"Model-based reasoning","score":0.4798157215118408},{"id":"https://openalex.org/keywords/semantics","display_name":"Semantics (computer science)","score":0.4600951075553894},{"id":"https://openalex.org/keywords/semantic-web","display_name":"Semantic Web","score":0.4414811134338379},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.37651970982551575},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.34379857778549194},{"id":"https://openalex.org/keywords/information-retrieval","display_name":"Information retrieval","score":0.3420991897583008},{"id":"https://openalex.org/keywords/knowledge-representation-and-reasoning","display_name":"Knowledge representation and reasoning","score":0.2989974319934845}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7392696738243103},{"id":"https://openalex.org/C37335422","wikidata":"https://www.wikidata.org/wiki/Q6888134","display_name":"Model-based reasoning","level":3,"score":0.4798157215118408},{"id":"https://openalex.org/C184337299","wikidata":"https://www.wikidata.org/wiki/Q1437428","display_name":"Semantics (computer science)","level":2,"score":0.4600951075553894},{"id":"https://openalex.org/C2129575","wikidata":"https://www.wikidata.org/wiki/Q54837","display_name":"Semantic Web","level":2,"score":0.4414811134338379},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.37651970982551575},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.34379857778549194},{"id":"https://openalex.org/C23123220","wikidata":"https://www.wikidata.org/wiki/Q816826","display_name":"Information retrieval","level":1,"score":0.3420991897583008},{"id":"https://openalex.org/C161301231","wikidata":"https://www.wikidata.org/wiki/Q3478658","display_name":"Knowledge representation and reasoning","level":2,"score":0.2989974319934845},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1186/s13040-017-0123-y","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13040-017-0123-y","pdf_url":"https://biodatamining.biomedcentral.com/track/pdf/10.1186/s13040-017-0123-y","source":{"id":"https://openalex.org/S84409260","display_name":"BioData Mining","issn_l":"1756-0381","issn":["1756-0381"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BioData Mining","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:5303296","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5303296","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BioData Min","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/s13040-017-0123-y","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13040-017-0123-y","pdf_url":"https://biodatamining.biomedcentral.com/track/pdf/10.1186/s13040-017-0123-y","source":{"id":"https://openalex.org/S84409260","display_name":"BioData Mining","issn_l":"1756-0381","issn":["1756-0381"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BioData Mining","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.7699999809265137,"id":"https://metadata.un.org/sdg/16","display_name":"Peace, Justice and strong institutions"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320334593","display_name":"Natural Sciences and Engineering Research Council of Canada","ror":"https://ror.org/01h531d29"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2587099845.pdf","grobid_xml":"https://content.openalex.org/works/W2587099845.grobid-xml"},"referenced_works_count":46,"referenced_works":["https://openalex.org/W147085412","https://openalex.org/W177590838","https://openalex.org/W901252737","https://openalex.org/W1486477330","https://openalex.org/W1499581632","https://openalex.org/W1501129163","https://openalex.org/W1507629289","https://openalex.org/W1521454415","https://openalex.org/W1548778571","https://openalex.org/W1600796577","https://openalex.org/W1604475812","https://openalex.org/W1642660396","https://openalex.org/W1981311312","https://openalex.org/W1995167134","https://openalex.org/W2018131536","https://openalex.org/W2021328408","https://openalex.org/W2046088169","https://openalex.org/W2063535110","https://openalex.org/W2077794025","https://openalex.org/W2079796285","https://openalex.org/W2079877696","https://openalex.org/W2081059384","https://openalex.org/W2094848746","https://openalex.org/W2095310997","https://openalex.org/W2099120848","https://openalex.org/W2099746791","https://openalex.org/W2105531864","https://openalex.org/W2107658719","https://openalex.org/W2119626405","https://openalex.org/W2126452789","https://openalex.org/W2136480620","https://openalex.org/W2137313573","https://openalex.org/W2149017759","https://openalex.org/W2156576948","https://openalex.org/W2162772535","https://openalex.org/W2165741325","https://openalex.org/W2171453670","https://openalex.org/W2178394434","https://openalex.org/W2398190973","https://openalex.org/W2401456545","https://openalex.org/W2797875826","https://openalex.org/W2911601159","https://openalex.org/W4213298329","https://openalex.org/W4230023680","https://openalex.org/W4249052738","https://openalex.org/W4388310255"],"related_works":["https://openalex.org/W4213212078","https://openalex.org/W2187227032","https://openalex.org/W2112788825","https://openalex.org/W1963735073","https://openalex.org/W4233129888","https://openalex.org/W106707639","https://openalex.org/W2146247781","https://openalex.org/W2144684733","https://openalex.org/W4299950557","https://openalex.org/W2575246084"],"abstract_inverted_index":{"Capturing":[0],"complete":[1],"medical":[2,20,33,120,182,210,336],"knowledge":[3,21,248,254,326,337],"is":[4,101,367],"challenging-often":[5],"due":[6],"to":[7,93,106,118,168,202,238,301,331,354,369],"incomplete":[8,32,209],"patient":[9],"Electronic":[10],"Health":[11],"Records":[12],"(EHR),":[13],"but":[14],"also":[15],"because":[16],"of":[17,31,132,184,195,208,216,227,252,273,296,327,335,360,377],"valuable,":[18],"tacit":[19],"hidden":[22],"away":[23],"in":[24,232,278,340],"physicians\u2019":[25],"experiences.":[26],"To":[27,212],"extend":[28,332],"the":[29,88,91,128,214,217,239,250,253,279,294,297,333,356],"coverage":[30,251,281,334],"knowledge-based":[34],"systems":[35,373],"beyond":[36],"their":[37,43],"deductive":[38,159,302],"closure,":[39],"and":[40,71,77,97,124,130,135,144,160,163,200,262,271,323,358],"thus":[41],"enhance":[42],"decision-support":[44],"capabilities,":[45],"we":[46,126,149,190,219,351],"argue":[47],"that":[48,245,288,315],"innovative,":[49],"multi-strategy":[50,154],"reasoning":[51,59,81,155,162,306,317,362],"approaches":[52],"should":[53],"be":[54],"applied.":[55],"In":[56,146],"particular,":[57],"plausible":[58,133,161,305,316,361],"mechanisms":[60,82,307],"apply":[61],"patterns":[62],"from":[63,188],"human":[64],"thought":[65],"processes,":[66],"such":[67,139],"as":[68,140],"generalization,":[69],"similarity":[70],"interpolation,":[72],"based":[73],"on":[74,257],"attributional,":[75],"hierarchical,":[76],"relational":[78],"knowledge.":[79,211],"Plausible":[80],"include":[83],"inductive":[84],"reasoning,":[85,99,134,303],"which":[86,100,157,189,230],"generalizes":[87],"commonalities":[89],"among":[90],"data":[92,104,141,196],"induce":[94],"new":[95,108],"rules,":[96],"analogical":[98],"guided":[102],"by":[103,319,346],"similarities":[105],"infer":[107],"facts.":[109],"By":[110],"further":[111],"leveraging":[112,324,347],"rich,":[113],"biomedical":[114],"Semantic":[115,152,165],"Web":[116,166],"ontologies":[117],"represent":[119],"knowledge,":[121,350],"both":[122],"known":[123],"tentative,":[125],"increase":[127,213,355],"accuracy":[129,359],"expressivity":[131,357],"cope":[136],"with":[137,186,205],"issues":[138],"heterogeneity,":[142],"inconsistency":[143],"interoperability.":[145],"this":[147],"paper,":[148],"present":[150],"a":[151,180,309,375],"Web-based,":[153],"approach,":[156],"integrates":[158],"exploits":[164],"technology":[167],"solve":[169],"complex":[170,284],"clinical":[171,342,370],"decision":[172,343,371],"support":[173,372],"queries.":[174],"We":[175,313],"evaluated":[176],"our":[177,365],"system":[178],"using":[179],"real-world":[181],"dataset":[183],"patients":[185],"hepatitis,":[187],"randomly":[191],"removed":[192],"different":[193],"percentages":[194],"(5%,":[197],"10%,":[198,269],"15%,":[199,270],"20%)":[201],"reflect":[203],"scenarios":[204],"increasing":[206],"amounts":[207],"reliability":[215],"results,":[218],"generated":[220],"5":[221],"independent":[222],"datasets":[223,235,265],"for":[224,264,374],"each":[225],"percentage":[226],"missing":[228,274],"values,":[229],"resulted":[231],"20":[233],"experimental":[234],"(in":[236],"addition":[237],"original":[240],"dataset).":[241],"The":[242],"results":[243],"show":[244],"plausibly":[246],"inferred":[247],"extends":[249],"base":[255],"by,":[256],"average,":[258],"2%,":[259],"7%,":[260],"12%,":[261],"16%":[263],"with,":[266],"respectively,":[267],"5%,":[268],"20%":[272],"values.":[275],"This":[276],"expansion":[277],"KB":[280],"allowed":[282],"solving":[283],"disease":[285],"diagnostic":[286],"queries":[287],"were":[289],"previously":[290],"unresolvable,":[291],"without":[292],"losing":[293],"correctness":[295],"answers.":[298],"However,":[299],"compared":[300],"data-intensive":[304],"yield":[308],"significant":[310],"performance":[311],"overhead.":[312],"observed":[314],"approaches,":[318],"generating":[320],"tentative":[321],"inferences":[322],"domain":[325],"experts,":[328],"allow":[329],"us":[330],"bases,":[338],"resulting":[339],"improved":[341],"support.":[344],"Second,":[345],"OWL":[348],"ontological":[349],"are":[352],"able":[353],"methods.":[363],"Third,":[364],"approach":[366],"applicable":[368],"range":[376],"chronic":[378],"diseases.":[379]},"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":6},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":2}],"updated_date":"2026-03-20T23:20:44.827607","created_date":"2017-02-17T00:00:00"}