{"id":"https://openalex.org/W2531260577","doi":"https://doi.org/10.1186/s13040-016-0111-7","title":"Low-mass-ion discriminant equation (LOME) for ovarian cancer screening","display_name":"Low-mass-ion discriminant equation (LOME) for ovarian cancer screening","publication_year":2016,"publication_date":"2016-10-12","ids":{"openalex":"https://openalex.org/W2531260577","doi":"https://doi.org/10.1186/s13040-016-0111-7","mag":"2531260577","pmid":"https://pubmed.ncbi.nlm.nih.gov/27752286"},"language":"en","primary_location":{"id":"doi:10.1186/s13040-016-0111-7","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13040-016-0111-7","pdf_url":"https://biodatamining.biomedcentral.com/track/pdf/10.1186/s13040-016-0111-7","source":{"id":"https://openalex.org/S84409260","display_name":"BioData Mining","issn_l":"1756-0381","issn":["1756-0381"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BioData Mining","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://biodatamining.biomedcentral.com/track/pdf/10.1186/s13040-016-0111-7","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5078711060","display_name":"Jun Hwa Lee","orcid":"https://orcid.org/0000-0001-9717-3677"},"institutions":[{"id":"https://openalex.org/I138925566","display_name":"Ewha Womans University","ror":"https://ror.org/053fp5c05","country_code":"KR","type":"education","lineage":["https://openalex.org/I138925566"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Jun Hwa Lee","raw_affiliation_strings":["Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Ewha Womans University Mokdong Hospital, College of Medicine, Ewha Womans University, Seoul, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Ewha Womans University Mokdong Hospital, College of Medicine, Ewha Womans University, Seoul, Republic of Korea","institution_ids":["https://openalex.org/I138925566"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063653461","display_name":"Byong Chul Yoo","orcid":"https://orcid.org/0000-0001-7937-0167"},"institutions":[{"id":"https://openalex.org/I4210089431","display_name":"National Cancer Center","ror":"https://ror.org/0065zqt33","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089431"]},{"id":"https://openalex.org/I4210120052","display_name":"National Cancer Center","ror":"https://ror.org/02tsanh21","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I1290491151","https://openalex.org/I2801339556","https://openalex.org/I4210120052"]}],"countries":["KR","US"],"is_corresponding":false,"raw_author_name":"Byong Chul Yoo","raw_affiliation_strings":["Colorectal Cancer Branch, Research Institute, National Cancer Center, Goyang, Gyeonggi Republic of Korea","Colorectal Cancer Branch, Research Institute, National Cancer Center, Goyang, Gyeonggi, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Colorectal Cancer Branch, Research Institute, National Cancer Center, Goyang, Gyeonggi Republic of Korea","institution_ids":["https://openalex.org/I4210089431","https://openalex.org/I4210120052"]},{"raw_affiliation_string":"Colorectal Cancer Branch, Research Institute, National Cancer Center, Goyang, Gyeonggi, Republic of Korea","institution_ids":["https://openalex.org/I4210120052"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025558509","display_name":"Yun Hwan Kim","orcid":"https://orcid.org/0000-0001-9498-2938"},"institutions":[{"id":"https://openalex.org/I138925566","display_name":"Ewha Womans University","ror":"https://ror.org/053fp5c05","country_code":"KR","type":"education","lineage":["https://openalex.org/I138925566"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Yun Hwan Kim","raw_affiliation_strings":["Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Ewha Womans University Mokdong Hospital, College of Medicine, Ewha Womans University, Seoul, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Ewha Womans University Mokdong Hospital, College of Medicine, Ewha Womans University, Seoul, Republic of Korea","institution_ids":["https://openalex.org/I138925566"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112221918","display_name":"Sun-A Ahn","orcid":null},"institutions":[{"id":"https://openalex.org/I4210089431","display_name":"National Cancer Center","ror":"https://ror.org/0065zqt33","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089431"]},{"id":"https://openalex.org/I4210120052","display_name":"National Cancer Center","ror":"https://ror.org/02tsanh21","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I1290491151","https://openalex.org/I2801339556","https://openalex.org/I4210120052"]}],"countries":["KR","US"],"is_corresponding":false,"raw_author_name":"Sun-A Ahn","raw_affiliation_strings":["Colorectal Cancer Branch, Research Institute, National Cancer Center, Goyang, Gyeonggi Republic of Korea","Colorectal Cancer Branch, Research Institute, National Cancer Center, Goyang, Gyeonggi, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Colorectal Cancer Branch, Research Institute, National Cancer Center, Goyang, Gyeonggi Republic of Korea","institution_ids":["https://openalex.org/I4210089431","https://openalex.org/I4210120052"]},{"raw_affiliation_string":"Colorectal Cancer Branch, Research Institute, National Cancer Center, Goyang, Gyeonggi, Republic of Korea","institution_ids":["https://openalex.org/I4210120052"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049429507","display_name":"Seung\u2010Gu Yeo","orcid":"https://orcid.org/0000-0003-1371-1381"},"institutions":[{"id":"https://openalex.org/I24541011","display_name":"Soonchunhyang University","ror":"https://ror.org/03qjsrb10","country_code":"KR","type":"education","lineage":["https://openalex.org/I24541011"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Seung-Gu Yeo","raw_affiliation_strings":["Department of Radiation Oncology, Soonchunhyang University College of Medicine, Cheonan, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Soonchunhyang University College of Medicine, Cheonan, Republic of Korea","institution_ids":["https://openalex.org/I24541011"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001534001","display_name":"Jae Youl Cho","orcid":"https://orcid.org/0000-0001-8141-9927"},"institutions":[{"id":"https://openalex.org/I848706","display_name":"Sungkyunkwan University","ror":"https://ror.org/04q78tk20","country_code":"KR","type":"education","lineage":["https://openalex.org/I848706"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Jae Youl Cho","raw_affiliation_strings":["Department of Genetic Engineering, Sungkyunkwan University, Suwon, Gyeonggi Republic of Korea","Department of Genetic Engineering, Sungkyunkwan University, Suwon, Gyeonggi, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetic Engineering, Sungkyunkwan University, Suwon, Gyeonggi Republic of Korea","institution_ids":["https://openalex.org/I848706"]},{"raw_affiliation_string":"Department of Genetic Engineering, Sungkyunkwan University, Suwon, Gyeonggi, Republic of Korea","institution_ids":["https://openalex.org/I848706"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100608883","display_name":"Kyung\u2010Hee Kim","orcid":"https://orcid.org/0000-0003-0214-0296"},"institutions":[{"id":"https://openalex.org/I4210089431","display_name":"National Cancer Center","ror":"https://ror.org/0065zqt33","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089431"]},{"id":"https://openalex.org/I4210120052","display_name":"National Cancer Center","ror":"https://ror.org/02tsanh21","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I1290491151","https://openalex.org/I2801339556","https://openalex.org/I4210120052"]}],"countries":["KR","US"],"is_corresponding":true,"raw_author_name":"Kyung-Hee Kim","raw_affiliation_strings":["Colorectal Cancer Branch, Research Institute, National Cancer Center, Goyang, Gyeonggi Republic of Korea","Omics Core Laboratory, Research Institute, National Cancer Center, Goyang, Gyeonggi Republic of Korea","Colorectal Cancer Branch, Research Institute, National Cancer Center, Goyang, Gyeonggi, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Colorectal Cancer Branch, Research Institute, National Cancer Center, Goyang, Gyeonggi Republic of Korea","institution_ids":["https://openalex.org/I4210089431","https://openalex.org/I4210120052"]},{"raw_affiliation_string":"Omics Core Laboratory, Research Institute, National Cancer Center, Goyang, Gyeonggi Republic of Korea","institution_ids":["https://openalex.org/I4210120052","https://openalex.org/I4210089431"]},{"raw_affiliation_string":"Colorectal Cancer Branch, Research Institute, National Cancer Center, Goyang, Gyeonggi, Republic of Korea","institution_ids":["https://openalex.org/I4210120052"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5045179524","display_name":"Seung Cheol Kim","orcid":"https://orcid.org/0000-0002-5000-9914"},"institutions":[{"id":"https://openalex.org/I138925566","display_name":"Ewha Womans University","ror":"https://ror.org/053fp5c05","country_code":"KR","type":"education","lineage":["https://openalex.org/I138925566"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Seung Cheol Kim","raw_affiliation_strings":["Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Ewha Womans University Mokdong Hospital, College of Medicine, Ewha Womans University, Seoul, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Ewha Womans University Mokdong Hospital, College of Medicine, Ewha Womans University, Seoul, Republic of Korea","institution_ids":["https://openalex.org/I138925566"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5045179524","https://openalex.org/A5100608883"],"corresponding_institution_ids":["https://openalex.org/I138925566","https://openalex.org/I4210089431","https://openalex.org/I4210120052"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2072},"fwci":0.8706,"has_fulltext":true,"cited_by_count":10,"citation_normalized_percentile":{"value":0.77099993,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"9","issue":"1","first_page":"32","last_page":"32"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10836","display_name":"Metabolomics and Mass Spectrometry Studies","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10836","display_name":"Metabolomics and Mass Spectrometry Studies","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10683","display_name":"Mass Spectrometry Techniques and Applications","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10519","display_name":"Advanced Proteomics Techniques and Applications","score":0.9973999857902527,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ovarian-cancer","display_name":"Ovarian cancer","score":0.6430526375770569},{"id":"https://openalex.org/keywords/mass-spectrometry","display_name":"Mass spectrometry","score":0.51402747631073},{"id":"https://openalex.org/keywords/linear-discriminant-analysis","display_name":"Linear discriminant analysis","score":0.4955404996871948},{"id":"https://openalex.org/keywords/glutamine","display_name":"Glutamine","score":0.42733699083328247},{"id":"https://openalex.org/keywords/fibrinogen","display_name":"Fibrinogen","score":0.4242987632751465},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.38469746708869934},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.3713340759277344},{"id":"https://openalex.org/keywords/oncology","display_name":"Oncology","score":0.3294452428817749},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.31029361486434937},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.3003586530685425},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.285584419965744},{"id":"https://openalex.org/keywords/chromatography","display_name":"Chromatography","score":0.2576928436756134},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.19046524167060852},{"id":"https://openalex.org/keywords/amino-acid","display_name":"Amino acid","score":0.12143173813819885},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.11888015270233154}],"concepts":[{"id":"https://openalex.org/C2780427987","wikidata":"https://www.wikidata.org/wiki/Q172341","display_name":"Ovarian cancer","level":3,"score":0.6430526375770569},{"id":"https://openalex.org/C162356407","wikidata":"https://www.wikidata.org/wiki/Q180809","display_name":"Mass spectrometry","level":2,"score":0.51402747631073},{"id":"https://openalex.org/C69738355","wikidata":"https://www.wikidata.org/wiki/Q1228929","display_name":"Linear discriminant analysis","level":2,"score":0.4955404996871948},{"id":"https://openalex.org/C2779349466","wikidata":"https://www.wikidata.org/wiki/Q181619","display_name":"Glutamine","level":3,"score":0.42733699083328247},{"id":"https://openalex.org/C2779036427","wikidata":"https://www.wikidata.org/wiki/Q381899","display_name":"Fibrinogen","level":2,"score":0.4242987632751465},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.38469746708869934},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.3713340759277344},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.3294452428817749},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.31029361486434937},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3003586530685425},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.285584419965744},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.2576928436756134},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.19046524167060852},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.12143173813819885},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.11888015270233154}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1186/s13040-016-0111-7","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13040-016-0111-7","pdf_url":"https://biodatamining.biomedcentral.com/track/pdf/10.1186/s13040-016-0111-7","source":{"id":"https://openalex.org/S84409260","display_name":"BioData Mining","issn_l":"1756-0381","issn":["1756-0381"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BioData Mining","raw_type":"journal-article"},{"id":"pmid:27752286","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/27752286","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BioData mining","raw_type":null},{"id":"pmh:oai:europepmc.org:4018389","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5059959","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/s13040-016-0111-7","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13040-016-0111-7","pdf_url":"https://biodatamining.biomedcentral.com/track/pdf/10.1186/s13040-016-0111-7","source":{"id":"https://openalex.org/S84409260","display_name":"BioData Mining","issn_l":"1756-0381","issn":["1756-0381"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BioData Mining","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/10","display_name":"Reduced inequalities","score":0.75}],"awards":[{"id":"https://openalex.org/G8744391891","display_name":null,"funder_award_id":"HI12C0050","funder_id":"https://openalex.org/F4320322034","funder_display_name":"Ministry of Health and Welfare"}],"funders":[{"id":"https://openalex.org/F4320322034","display_name":"Ministry of Health and Welfare","ror":"https://ror.org/00vxgjw72"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2531260577.pdf","grobid_xml":"https://content.openalex.org/works/W2531260577.grobid-xml"},"referenced_works_count":23,"referenced_works":["https://openalex.org/W1540722338","https://openalex.org/W1601747688","https://openalex.org/W1745785199","https://openalex.org/W1977802164","https://openalex.org/W1984964160","https://openalex.org/W1986958762","https://openalex.org/W1993038196","https://openalex.org/W2011628468","https://openalex.org/W2029884260","https://openalex.org/W2043477105","https://openalex.org/W2052425409","https://openalex.org/W2065342065","https://openalex.org/W2082730398","https://openalex.org/W2086816631","https://openalex.org/W2131441288","https://openalex.org/W2134919151","https://openalex.org/W2139503709","https://openalex.org/W2140903090","https://openalex.org/W2159550690","https://openalex.org/W2162790428","https://openalex.org/W2165279893","https://openalex.org/W2219161659","https://openalex.org/W2283847485"],"related_works":["https://openalex.org/W2406642749","https://openalex.org/W2378801674","https://openalex.org/W2003348660","https://openalex.org/W2431439348","https://openalex.org/W2119738915","https://openalex.org/W2111784969","https://openalex.org/W2081780014","https://openalex.org/W2016733795","https://openalex.org/W1965723613","https://openalex.org/W2056164272"],"abstract_inverted_index":{"A":[0],"low-mass-ion":[1,11],"discriminant":[2,77],"equation":[3],"(LOME)":[4],"was":[5,30,138],"constructed":[6],"to":[7,17,32,43,85,163],"investigate":[8],"whether":[9],"systematic":[10],"(LMI)":[12],"profiling":[13],"could":[14,198],"be":[15,182],"applied":[16],"ovarian":[18],"cancer":[19],"(OVC)":[20],"screening.":[21,194],"Matrix-assisted":[22],"laser":[23],"desorption/ionization-time":[24],"of":[25,50,66,71,135,207,219],"flight":[26],"(MALDI-TOF)":[27],"mass":[28,34,121],"spectrometry":[29],"performed":[31],"obtain":[33],"spectral":[35],"data":[36],"on":[37,210],"metabolites":[38],"detected":[39],"as":[40],"LMIs":[41,101,118],"up":[42],"a":[44,107,183,211],"mass-to-charge":[45],"ratio":[46],"(":[47,167],"m/z":[48],")":[49],"2500":[51],"for":[52,90,192,201,235],"1184":[53],"serum":[54,217],"samples":[55],"collected":[56],"from":[57,93],"healthy":[58],"individuals":[59],"and":[60,79,130,152,171,190,228],"patients":[61],"with":[62,98,187],"OVC,":[63,124,142],"other":[64],"types":[65,70,206],"cancer,":[67,208],"or":[68],"several":[69],"benign":[72],"tumor.":[73],"Principal":[74],"component":[75],"analysis-based":[76],"analysis":[78],"two":[80],"search":[81],"algorithms":[82],"were":[83,128,157],"employed":[84],"identify":[86],"discriminative":[87,100],"low-mass":[88],"ions":[89],"distinguishing":[91],"OVC":[92,96,161,179,193],"non-OVC":[94],"cases.":[95],"LOME":[97,180,196],"13":[99,117],"produced":[102],"excellent":[103],"classification":[104],"results":[105],"in":[106,123,141,160],"validation":[108],"set":[109],"(sensitivity,":[110],"93.10":[111],"%;":[112],"specificity,":[113],"100.0":[114],"%).":[115],"Among":[116],"showing":[119],"differential":[120],"intensities":[122],"3":[125],"metabolic":[126,221],"compounds":[127],"identified":[129],"semi-quantitated.":[131],"The":[132,174,195],"relative":[133],"amount":[134],"LPC":[136,226],"16:0":[137,227],"somewhat":[139],"decreased":[140],"but":[143],"not":[144],"significantly":[145,158],"so.":[146],"In":[147],"contrast,":[148],"D,L":[149,223],"-":[150,224],"glutamine":[151],"fibrinogen":[153,229],"alpha":[154,230],"chain":[155,231],"fragment":[156],"increased":[159],"compared":[162],"the":[164,216],"control":[165],"group":[166],"p":[168],"=":[169],"0.001":[170],"0.002,":[172],"respectively).":[173],"present":[175],"study":[176],"suggested":[177],"that":[178],"might":[181],"useful":[184],"non-invasive":[185],"tool":[186],"high":[188],"sensitivity":[189],"specificity":[191],"approach":[197],"enable":[199],"screening":[200,234],"multiple":[202],"diseases,":[203],"including":[204],"various":[205],"based":[209],"single":[212],"blood":[213],"sample.":[214],"Furthermore,":[215],"levels":[218],"three":[220],"compounds\u2014":[222],"glutamine,":[225],"fragment\u2014might":[232],"facilitate":[233],"OVC.":[236]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":3}],"updated_date":"2026-06-19T15:47:20.252518","created_date":"2016-10-21T00:00:00"}