{"id":"https://openalex.org/W1552885745","doi":"https://doi.org/10.1186/s13040-015-0048-2","title":"The effects of electronic medical record phenotyping details on genetic association studies: HDL-C as a case study","display_name":"The effects of electronic medical record phenotyping details on genetic association studies: HDL-C as a case study","publication_year":2015,"publication_date":"2015-05-05","ids":{"openalex":"https://openalex.org/W1552885745","doi":"https://doi.org/10.1186/s13040-015-0048-2","mag":"1552885745","pmid":"https://pubmed.ncbi.nlm.nih.gov/25969697"},"language":"en","primary_location":{"id":"doi:10.1186/s13040-015-0048-2","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13040-015-0048-2","pdf_url":"https://biodatamining.biomedcentral.com/counter/pdf/10.1186/s13040-015-0048-2","source":{"id":"https://openalex.org/S84409260","display_name":"BioData Mining","issn_l":"1756-0381","issn":["1756-0381"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BioData Mining","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://biodatamining.biomedcentral.com/counter/pdf/10.1186/s13040-015-0048-2","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5028690751","display_name":"Logan Dumitrescu","orcid":"https://orcid.org/0000-0002-9782-9944"},"institutions":[{"id":"https://openalex.org/I4210105714","display_name":"Center for Human Genetics","ror":"https://ror.org/01gcrbc43","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210105714"]},{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Logan Dumitrescu","raw_affiliation_strings":["Center for Human Genetics Research, Vanderbilt University, 2215 Garland Avenue, 519 Light Hall, Nashville, TN 37232 USA ; Department of Molecular Physiology and Biophysics, Vanderbilt University, 2215 Garland Avenue, 519 Light Hall, Nashville, TN 37232 USA","Center for Human Genetics Research, Vanderbilt University, 2215 Garland Avenue, 519 Light Hall, Nashville, TN, 37232, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Human Genetics Research, Vanderbilt University, 2215 Garland Avenue, 519 Light Hall, Nashville, TN 37232 USA ; Department of Molecular Physiology and Biophysics, Vanderbilt University, 2215 Garland Avenue, 519 Light Hall, Nashville, TN 37232 USA","institution_ids":[]},{"raw_affiliation_string":"Center for Human Genetics Research, Vanderbilt University, 2215 Garland Avenue, 519 Light Hall, Nashville, TN, 37232, USA","institution_ids":["https://openalex.org/I200719446","https://openalex.org/I4210105714"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004271140","display_name":"Robert Goodloe","orcid":null},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]},{"id":"https://openalex.org/I4210105714","display_name":"Center for Human Genetics","ror":"https://ror.org/01gcrbc43","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210105714"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert Goodloe","raw_affiliation_strings":["Center for Human Genetics Research, Vanderbilt University, 2215 Garland Avenue, 519 Light Hall, Nashville, TN 37232 USA ; Department of Molecular Physiology and Biophysics, Vanderbilt University, 2215 Garland Avenue, 519 Light Hall, Nashville, TN 37232 USA","Center for Human Genetics Research, Vanderbilt University, 2215 Garland Avenue, 519 Light Hall, Nashville, TN, 37232, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Human Genetics Research, Vanderbilt University, 2215 Garland Avenue, 519 Light Hall, Nashville, TN 37232 USA ; Department of Molecular Physiology and Biophysics, Vanderbilt University, 2215 Garland Avenue, 519 Light Hall, Nashville, TN 37232 USA","institution_ids":[]},{"raw_affiliation_string":"Center for Human Genetics Research, Vanderbilt University, 2215 Garland Avenue, 519 Light Hall, Nashville, TN, 37232, USA","institution_ids":["https://openalex.org/I200719446","https://openalex.org/I4210105714"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031170199","display_name":"Yukiko Bradford","orcid":null},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yukiko Bradford","raw_affiliation_strings":["Center for Systems Genomics, Department of Biochemistry and Molecular Biology, The Pennsylvania State University, 512 Wartik Laboratory, University Park, PA 16802 USA","Center for Systems Genomics, Department of Biochemistry and Molecular Biology, The Pennsylvania State University, 512 Wartik Laboratory, University Park, PA, 16802, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Systems Genomics, Department of Biochemistry and Molecular Biology, The Pennsylvania State University, 512 Wartik Laboratory, University Park, PA 16802 USA","institution_ids":[]},{"raw_affiliation_string":"Center for Systems Genomics, Department of Biochemistry and Molecular Biology, The Pennsylvania State University, 512 Wartik Laboratory, University Park, PA, 16802, USA","institution_ids":["https://openalex.org/I130769515"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027840210","display_name":"Eric Farber\u2010Eger","orcid":"https://orcid.org/0000-0003-0281-3796"},"institutions":[{"id":"https://openalex.org/I4210105714","display_name":"Center for Human Genetics","ror":"https://ror.org/01gcrbc43","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210105714"]},{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eric Farber-Eger","raw_affiliation_strings":["Center for Human Genetics Research, Vanderbilt University, 2215 Garland Avenue, 519 Light Hall, Nashville, TN 37232 USA","Center for Human Genetics Research, Vanderbilt University, 2215 Garland Avenue, 519 Light Hall, Nashville, TN, 37232, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Human Genetics Research, Vanderbilt University, 2215 Garland Avenue, 519 Light Hall, Nashville, TN 37232 USA","institution_ids":[]},{"raw_affiliation_string":"Center for Human Genetics Research, Vanderbilt University, 2215 Garland Avenue, 519 Light Hall, Nashville, TN, 37232, USA","institution_ids":["https://openalex.org/I200719446","https://openalex.org/I4210105714"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040968528","display_name":"J.R. Boston","orcid":"https://orcid.org/0000-0002-5758-4479"},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]},{"id":"https://openalex.org/I4210105714","display_name":"Center for Human Genetics","ror":"https://ror.org/01gcrbc43","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210105714"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jonathan Boston","raw_affiliation_strings":["Center for Human Genetics Research, Vanderbilt University, 2215 Garland Avenue, 519 Light Hall, Nashville, TN 37232 USA","Center for Human Genetics Research, Vanderbilt University, 2215 Garland Avenue, 519 Light Hall, Nashville, TN, 37232, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Human Genetics Research, Vanderbilt University, 2215 Garland Avenue, 519 Light Hall, Nashville, TN 37232 USA","institution_ids":[]},{"raw_affiliation_string":"Center for Human Genetics Research, Vanderbilt University, 2215 Garland Avenue, 519 Light Hall, Nashville, TN, 37232, USA","institution_ids":["https://openalex.org/I200719446","https://openalex.org/I4210105714"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5039699723","display_name":"Dana C. Crawford","orcid":"https://orcid.org/0000-0002-6437-6248"},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]},{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Dana C Crawford","raw_affiliation_strings":["Department of Epidemiology and Biostatistics, Institute for Computational Biology, Case Western Reserve University, Wolstein Research Building, 2103 Cornell Road, Suite 2527, Cleveland, OH 44106 USA","Department of Epidemiology and Biostatistics, Institute for Computational Biology, Case Western Reserve University, Wolstein Research Building, 2103 Cornell Road, Suite 2527, Cleveland, OH, 44106, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology and Biostatistics, Institute for Computational Biology, Case Western Reserve University, Wolstein Research Building, 2103 Cornell Road, Suite 2527, Cleveland, OH 44106 USA","institution_ids":[]},{"raw_affiliation_string":"Department of Epidemiology and Biostatistics, Institute for Computational Biology, Case Western Reserve University, Wolstein Research Building, 2103 Cornell Road, Suite 2527, Cleveland, OH, 44106, USA","institution_ids":["https://openalex.org/I58956616","https://openalex.org/I205783295"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5039699723"],"corresponding_institution_ids":["https://openalex.org/I205783295","https://openalex.org/I58956616"],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2072},"fwci":1.7082,"has_fulltext":true,"cited_by_count":11,"citation_normalized_percentile":{"value":0.85124932,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"8","issue":"1","first_page":"15","last_page":"15"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.9574999809265137,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.9574999809265137,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11642","display_name":"Genomics and Rare Diseases","score":0.008799999952316284,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":0.00839999970048666,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/trait","display_name":"Trait","score":0.6161119341850281},{"id":"https://openalex.org/keywords/genetic-architecture","display_name":"Genetic architecture","score":0.612497091293335},{"id":"https://openalex.org/keywords/genetic-association","display_name":"Genetic association","score":0.5997653603553772},{"id":"https://openalex.org/keywords/association","display_name":"Association (psychology)","score":0.5143054723739624},{"id":"https://openalex.org/keywords/genome-wide-association-study","display_name":"Genome-wide association study","score":0.4371112287044525},{"id":"https://openalex.org/keywords/covariate","display_name":"Covariate","score":0.4218590557575226},{"id":"https://openalex.org/keywords/phenotype","display_name":"Phenotype","score":0.41970905661582947},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.39547568559646606},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.3629140853881836},{"id":"https://openalex.org/keywords/genotype","display_name":"Genotype","score":0.3583616018295288},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.3420019745826721},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.32143235206604004},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.3158565163612366},{"id":"https://openalex.org/keywords/single-nucleotide-polymorphism","display_name":"Single-nucleotide polymorphism","score":0.2540830969810486},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.25214263796806335},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.2278028130531311},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.225541889667511},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.21824488043785095}],"concepts":[{"id":"https://openalex.org/C106934330","wikidata":"https://www.wikidata.org/wiki/Q1971873","display_name":"Trait","level":2,"score":0.6161119341850281},{"id":"https://openalex.org/C9287583","wikidata":"https://www.wikidata.org/wiki/Q5532883","display_name":"Genetic architecture","level":4,"score":0.612497091293335},{"id":"https://openalex.org/C186413461","wikidata":"https://www.wikidata.org/wiki/Q744727","display_name":"Genetic association","level":5,"score":0.5997653603553772},{"id":"https://openalex.org/C142853389","wikidata":"https://www.wikidata.org/wiki/Q744778","display_name":"Association (psychology)","level":2,"score":0.5143054723739624},{"id":"https://openalex.org/C106208931","wikidata":"https://www.wikidata.org/wiki/Q1098876","display_name":"Genome-wide association study","level":5,"score":0.4371112287044525},{"id":"https://openalex.org/C119043178","wikidata":"https://www.wikidata.org/wiki/Q320723","display_name":"Covariate","level":2,"score":0.4218590557575226},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.41970905661582947},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.39547568559646606},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3629140853881836},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.3583616018295288},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3420019745826721},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.32143235206604004},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3158565163612366},{"id":"https://openalex.org/C153209595","wikidata":"https://www.wikidata.org/wiki/Q501128","display_name":"Single-nucleotide polymorphism","level":4,"score":0.2540830969810486},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.25214263796806335},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2278028130531311},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.225541889667511},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.21824488043785095},{"id":"https://openalex.org/C542102704","wikidata":"https://www.wikidata.org/wiki/Q183257","display_name":"Psychotherapist","level":1,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1186/s13040-015-0048-2","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13040-015-0048-2","pdf_url":"https://biodatamining.biomedcentral.com/counter/pdf/10.1186/s13040-015-0048-2","source":{"id":"https://openalex.org/S84409260","display_name":"BioData Mining","issn_l":"1756-0381","issn":["1756-0381"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BioData Mining","raw_type":"journal-article"},{"id":"pmid:25969697","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25969697","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BioData mining","raw_type":null},{"id":"pmh:oai:europepmc.org:3388942","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4428098","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/s13040-015-0048-2","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13040-015-0048-2","pdf_url":"https://biodatamining.biomedcentral.com/counter/pdf/10.1186/s13040-015-0048-2","source":{"id":"https://openalex.org/S84409260","display_name":"BioData Mining","issn_l":"1756-0381","issn":["1756-0381"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BioData Mining","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.7900000214576721,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"awards":[{"id":"https://openalex.org/G1730842257","display_name":null,"funder_award_id":"UL1 TR000445","funder_id":"https://openalex.org/F4320337472","funder_display_name":"National Center for Advancing Translational Sciences"},{"id":"https://openalex.org/G2092163535","display_name":null,"funder_award_id":"TR000445","funder_id":"https://openalex.org/F4320337472","funder_display_name":"National Center for Advancing Translational Sciences"},{"id":"https://openalex.org/G2209161966","display_name":null,"funder_award_id":"TR000445","funder_id":"https://openalex.org/F4320316438","funder_display_name":"Georgia Clinical and Translational Science Alliance"},{"id":"https://openalex.org/G2882208709","display_name":null,"funder_award_id":"U01 HG004603","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G4425699080","display_name":null,"funder_award_id":"TR000445","funder_id":"https://openalex.org/F4320309151","funder_display_name":"Vanderbilt University"},{"id":"https://openalex.org/G5497345335","display_name":null,"funder_award_id":"U01 HG004798","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G6451986917","display_name":null,"funder_award_id":"TR000445","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G6763566413","display_name":null,"funder_award_id":"UL1 TR000445","funder_id":"https://openalex.org/F4320309151","funder_display_name":"Vanderbilt University"},{"id":"https://openalex.org/G971891739","display_name":null,"funder_award_id":"UL1 TR000445","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320309151","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34"},{"id":"https://openalex.org/F4320313998","display_name":"Vanderbilt University Medical Center","ror":"https://ror.org/05dq2gs74"},{"id":"https://openalex.org/F4320316438","display_name":"Georgia Clinical and Translational Science Alliance","ror":null},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337472","display_name":"National Center for Advancing Translational Sciences","ror":"https://ror.org/04pw6fb54"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1552885745.pdf","grobid_xml":"https://content.openalex.org/works/W1552885745.grobid-xml"},"referenced_works_count":33,"referenced_works":["https://openalex.org/W1516041857","https://openalex.org/W1978359174","https://openalex.org/W1993333521","https://openalex.org/W1996133499","https://openalex.org/W2006776184","https://openalex.org/W2011455194","https://openalex.org/W2011980051","https://openalex.org/W2015940760","https://openalex.org/W2016104730","https://openalex.org/W2017406452","https://openalex.org/W2027867013","https://openalex.org/W2029119894","https://openalex.org/W2041467022","https://openalex.org/W2042809656","https://openalex.org/W2061605978","https://openalex.org/W2064337796","https://openalex.org/W2096841400","https://openalex.org/W2100429291","https://openalex.org/W2105058392","https://openalex.org/W2105753511","https://openalex.org/W2107021160","https://openalex.org/W2107862628","https://openalex.org/W2111202666","https://openalex.org/W2126226045","https://openalex.org/W2142071150","https://openalex.org/W2147383712","https://openalex.org/W2152410429","https://openalex.org/W2152741971","https://openalex.org/W2161633633","https://openalex.org/W2270172181","https://openalex.org/W2726651211","https://openalex.org/W2875586667","https://openalex.org/W2898172712"],"related_works":["https://openalex.org/W3098014387","https://openalex.org/W2754869062","https://openalex.org/W2986919234","https://openalex.org/W2982417329","https://openalex.org/W3195469724","https://openalex.org/W2923859939","https://openalex.org/W4210605760","https://openalex.org/W1971424770","https://openalex.org/W2142550298","https://openalex.org/W2148749248"],"abstract_inverted_index":{"BACKGROUND:":[0],"Biorepositories":[1],"linked":[2],"to":[3,12,39,86,136,159],"de-identified":[4],"electronic":[5],"medical":[6],"records":[7],"(EMRs)":[8],"have":[9],"the":[10,34,73,82,92,109,145,177,186],"potential":[11,32],"complement":[13],"traditional":[14,49],"epidemiologic":[15,50],"studies":[16,19],"in":[17,29],"genotype-phenotype":[18],"of":[20,36,68,84,94,153,163],"complex":[21],"human":[22],"diseases":[23],"and":[24,42,59,167,205],"traits.":[25],"A":[26],"major":[27],"challenge":[28],"meeting":[30],"this":[31,199],"is":[33],"use":[35],"EMR-derived":[37,52,104],"data":[38,53,70,192],"extract":[40,87,137],"phenotypes":[41,88],"covariates":[43],"for":[44,56,89,101,120,156,171,198],"genetic":[45,116,168,178,212],"association":[46,117,164,213],"studies.":[47],"Unlike":[48],"data,":[51],"are":[54,60],"collected":[55],"clinical":[57,69,79],"care":[58],"therefore":[61],"highly":[62],"variable":[63],"across":[64,185],"patients.":[65],"The":[66],"variability":[67],"coupled":[71],"with":[72,76],"challenges":[74],"associated":[75,173],"searching":[77],"unstructured":[78],"notes":[80],"requires":[81],"development":[83],"algorithms":[85,96,135],"analysis.":[90],"Given":[91],"number":[93],"possible":[95],"that":[97,176],"could":[98],"be":[99],"developed":[100],"any":[102],"one":[103],"phenotype,":[105],"we":[106],"explored":[107],"here":[108],"impact":[110,211],"algorithm":[111,202],"decision":[112,203],"logic":[113,204],"has":[114],"on":[115,144],"study":[118,214],"results":[119],"a":[121],"single":[122],"quantitative":[123,200],"trait,":[124,201],"high":[125],"density":[126],"lipoprotein":[127],"cholesterol":[128],"(HDL-C).":[129],"RESULTS:":[130],"We":[131],"used":[132],"five":[133,187],"different":[134],"HDL-C":[138,166,172,188],"from":[139],"African":[140],"American":[141],"subjects":[142],"genotyped":[143],"Illumina":[146],"Metabochip":[147],"(n":[148],"=":[149],"11,519)":[150],"as":[151],"part":[152],"Epidemiologic":[154],"Architecture":[155],"Genes":[157],"Linked":[158],"Environment":[160],"(EAGLE).":[161],"Tests":[162],"between":[165],"risk":[169],"scores":[170],"variants":[174],"suggest":[175,194],"effect":[179],"size":[180],"does":[181],"not":[182,209],"vary":[183],"substantially":[184],"definitions.":[189],"CONCLUSIONS:":[190],"These":[191],"collectively":[193],"that,":[195],"at":[196],"least":[197],"phenotyping":[206],"details":[207],"do":[208],"appreciably":[210],"test":[215],"statistics.":[216]},"counts_by_year":[{"year":2023,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":3}],"updated_date":"2026-05-08T15:41:06.802602","created_date":"2025-10-10T00:00:00"}