{"id":"https://openalex.org/W2102166268","doi":"https://doi.org/10.1186/s13040-015-0042-8","title":"Cancer based pharmacogenomics network supported with scientific evidences: from the view of drug repurposing","display_name":"Cancer based pharmacogenomics network supported with scientific evidences: from the view of drug repurposing","publication_year":2015,"publication_date":"2015-02-24","ids":{"openalex":"https://openalex.org/W2102166268","doi":"https://doi.org/10.1186/s13040-015-0042-8","mag":"2102166268","pmid":"https://pubmed.ncbi.nlm.nih.gov/25729430"},"language":"en","primary_location":{"id":"doi:10.1186/s13040-015-0042-8","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13040-015-0042-8","pdf_url":"https://biodatamining.biomedcentral.com/counter/pdf/10.1186/s13040-015-0042-8","source":{"id":"https://openalex.org/S84409260","display_name":"BioData Mining","issn_l":"1756-0381","issn":["1756-0381"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BioData Mining","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://biodatamining.biomedcentral.com/counter/pdf/10.1186/s13040-015-0042-8","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100406707","display_name":"Liwei Wang","orcid":"https://orcid.org/0000-0001-6985-9698"},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Liwei Wang","raw_affiliation_strings":["Department of Medical Informatics, School of Public Health, Jilin University, Changchun, 130021 China"],"affiliations":[{"raw_affiliation_string":"Department of Medical Informatics, School of Public Health, Jilin University, Changchun, 130021 China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101585391","display_name":"Hongfang Liu","orcid":"https://orcid.org/0000-0003-2570-3741"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hongfang Liu","raw_affiliation_strings":["Department of Health Science Research, Mayo Clinic, Rochester, MN 55901 USA","Department of Health Science research, Mayo Clinic, Rochester, MN 55901, USA"],"affiliations":[{"raw_affiliation_string":"Department of Health Science Research, Mayo Clinic, Rochester, MN 55901 USA","institution_ids":[]},{"raw_affiliation_string":"Department of Health Science research, Mayo Clinic, Rochester, MN 55901, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060390916","display_name":"Christopher G. Chute","orcid":"https://orcid.org/0000-0001-5437-2545"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Christopher G Chute","raw_affiliation_strings":["Division of General Internal Medicine, Johns Hopkins University, Baltimore, MD 21287 USA"],"affiliations":[{"raw_affiliation_string":"Division of General Internal Medicine, Johns Hopkins University, Baltimore, MD 21287 USA","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5073074181","display_name":"Qian Zhu","orcid":"https://orcid.org/0000-0002-4858-6333"},"institutions":[{"id":"https://openalex.org/I79272384","display_name":"University of Maryland, Baltimore County","ror":"https://ror.org/02qskvh78","country_code":"US","type":"education","lineage":["https://openalex.org/I79272384"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Qian Zhu","raw_affiliation_strings":["Department of Information Systems, University of Maryland Baltimore County, Baltimore, MD 21055 USA","\u00a0 University of Maryland, Baltimore County"],"affiliations":[{"raw_affiliation_string":"Department of Information Systems, University of Maryland Baltimore County, Baltimore, MD 21055 USA","institution_ids":[]},{"raw_affiliation_string":"\u00a0 University of Maryland, Baltimore County","institution_ids":["https://openalex.org/I79272384"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5100406707"],"corresponding_institution_ids":[],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072},"apc_paid":{"value":1690,"currency":"GBP","value_usd":2072},"fwci":1.3556,"has_fulltext":true,"cited_by_count":13,"citation_normalized_percentile":{"value":0.80640971,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":97},"biblio":{"volume":"8","issue":"1","first_page":"9","last_page":"9"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11710","display_name":"Biomedical Text Mining and Ontologies","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11710","display_name":"Biomedical Text Mining and Ontologies","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10375","display_name":"Pharmacogenetics and Drug Metabolism","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9934999942779541,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pharmacogenomics","display_name":"Pharmacogenomics","score":0.9509787559509277},{"id":"https://openalex.org/keywords/drug-repositioning","display_name":"Drug repositioning","score":0.8610531091690063},{"id":"https://openalex.org/keywords/repurposing","display_name":"Repurposing","score":0.7499619722366333},{"id":"https://openalex.org/keywords/drug-response","display_name":"Drug response","score":0.513929545879364},{"id":"https://openalex.org/keywords/genome-wide-association-study","display_name":"Genome-wide association study","score":0.5062662363052368},{"id":"https://openalex.org/keywords/precision-medicine","display_name":"Precision medicine","score":0.4966889023780823},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.48439890146255493},{"id":"https://openalex.org/keywords/single-nucleotide-polymorphism","display_name":"Single-nucleotide polymorphism","score":0.442515105009079},{"id":"https://openalex.org/keywords/drug","display_name":"Drug","score":0.4371168613433838},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.4349168837070465},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.39969563484191895},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.2859318256378174},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.26334309577941895},{"id":"https://openalex.org/keywords/pharmacology","display_name":"Pharmacology","score":0.1671084463596344},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.130630761384964},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.11521878838539124},{"id":"https://openalex.org/keywords/genotype","display_name":"Genotype","score":0.07592865824699402}],"concepts":[{"id":"https://openalex.org/C170734499","wikidata":"https://www.wikidata.org/wiki/Q1152227","display_name":"Pharmacogenomics","level":2,"score":0.9509787559509277},{"id":"https://openalex.org/C103637391","wikidata":"https://www.wikidata.org/wiki/Q5308921","display_name":"Drug repositioning","level":3,"score":0.8610531091690063},{"id":"https://openalex.org/C519536355","wikidata":"https://www.wikidata.org/wiki/Q21021151","display_name":"Repurposing","level":2,"score":0.7499619722366333},{"id":"https://openalex.org/C2994119904","wikidata":"https://www.wikidata.org/wiki/Q1251001","display_name":"Drug response","level":3,"score":0.513929545879364},{"id":"https://openalex.org/C106208931","wikidata":"https://www.wikidata.org/wiki/Q1098876","display_name":"Genome-wide association study","level":5,"score":0.5062662363052368},{"id":"https://openalex.org/C163763905","wikidata":"https://www.wikidata.org/wiki/Q17075943","display_name":"Precision medicine","level":2,"score":0.4966889023780823},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.48439890146255493},{"id":"https://openalex.org/C153209595","wikidata":"https://www.wikidata.org/wiki/Q501128","display_name":"Single-nucleotide polymorphism","level":4,"score":0.442515105009079},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.4371168613433838},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4349168837070465},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.39969563484191895},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.2859318256378174},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.26334309577941895},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.1671084463596344},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.130630761384964},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.11521878838539124},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.07592865824699402},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1186/s13040-015-0042-8","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13040-015-0042-8","pdf_url":"https://biodatamining.biomedcentral.com/counter/pdf/10.1186/s13040-015-0042-8","source":{"id":"https://openalex.org/S84409260","display_name":"BioData Mining","issn_l":"1756-0381","issn":["1756-0381"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BioData Mining","raw_type":"journal-article"},{"id":"pmid:25729430","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25729430","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BioData mining","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:4345035","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4345035","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BioData Min","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/s13040-015-0042-8","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13040-015-0042-8","pdf_url":"https://biodatamining.biomedcentral.com/counter/pdf/10.1186/s13040-015-0042-8","source":{"id":"https://openalex.org/S84409260","display_name":"BioData Mining","issn_l":"1756-0381","issn":["1756-0381"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BioData Mining","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.5799999833106995,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"awards":[{"id":"https://openalex.org/G4359693134","display_name":null,"funder_award_id":"NIGMS","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G5698604015","display_name":null,"funder_award_id":"61388","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G6598467477","display_name":null,"funder_award_id":"U19 GM61388","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G7136283870","display_name":null,"funder_award_id":"U19 GM61388","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G8127457510","display_name":null,"funder_award_id":"GM61388","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G8515188616","display_name":null,"funder_award_id":"GM61388","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2102166268.pdf","grobid_xml":"https://content.openalex.org/works/W2102166268.grobid-xml"},"referenced_works_count":47,"referenced_works":["https://openalex.org/W117980225","https://openalex.org/W305884220","https://openalex.org/W1487060125","https://openalex.org/W1529522905","https://openalex.org/W1540315694","https://openalex.org/W1596295448","https://openalex.org/W1608124137","https://openalex.org/W1854214752","https://openalex.org/W1886389877","https://openalex.org/W1934602670","https://openalex.org/W1981925077","https://openalex.org/W1986745503","https://openalex.org/W1987063085","https://openalex.org/W2000860171","https://openalex.org/W2018336040","https://openalex.org/W2023160939","https://openalex.org/W2025912784","https://openalex.org/W2031213082","https://openalex.org/W2036250027","https://openalex.org/W2043583138","https://openalex.org/W2054470867","https://openalex.org/W2064889510","https://openalex.org/W2082650750","https://openalex.org/W2096525273","https://openalex.org/W2103427999","https://openalex.org/W2112162466","https://openalex.org/W2115680280","https://openalex.org/W2122227419","https://openalex.org/W2123152121","https://openalex.org/W2123574746","https://openalex.org/W2127069089","https://openalex.org/W2128561460","https://openalex.org/W2135523574","https://openalex.org/W2144631782","https://openalex.org/W2149151184","https://openalex.org/W2159482845","https://openalex.org/W2159583324","https://openalex.org/W2162323699","https://openalex.org/W2164796706","https://openalex.org/W2170146596","https://openalex.org/W2404369708","https://openalex.org/W2479003177","https://openalex.org/W2624907881","https://openalex.org/W2971629451","https://openalex.org/W4239696231","https://openalex.org/W4244606935","https://openalex.org/W4294216483"],"related_works":["https://openalex.org/W2899096130","https://openalex.org/W3190782215","https://openalex.org/W2902729297","https://openalex.org/W3110500039","https://openalex.org/W4255531208","https://openalex.org/W4320009247","https://openalex.org/W4206422705","https://openalex.org/W3186872001","https://openalex.org/W3174741986","https://openalex.org/W2159063798"],"abstract_inverted_index":{"The":[0],"CPN":[1],"established":[2],"in":[3],"this":[4],"study":[5],"offers":[6],"comprehensive":[7],"cancer":[8,14],"based":[9],"PGx":[10],"information":[11],"to":[12],"support":[13],"orientated":[15],"research,":[16],"especially":[17],"for":[18],"drug":[19],"repurposing.":[20]},"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":2},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":1}],"updated_date":"2026-03-20T23:20:44.827607","created_date":"2025-10-10T00:00:00"}