{"id":"https://openalex.org/W2771671371","doi":"https://doi.org/10.1186/s13015-017-0112-1","title":"A hybrid parameter estimation algorithm for beta mixtures and applications to methylation state classification","display_name":"A hybrid parameter estimation algorithm for beta mixtures and applications to methylation state classification","publication_year":2017,"publication_date":"2017-08-18","ids":{"openalex":"https://openalex.org/W2771671371","doi":"https://doi.org/10.1186/s13015-017-0112-1","mag":"2771671371","pmid":"https://pubmed.ncbi.nlm.nih.gov/28828033"},"language":"en","primary_location":{"id":"doi:10.1186/s13015-017-0112-1","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13015-017-0112-1","pdf_url":"https://almob.biomedcentral.com/track/pdf/10.1186/s13015-017-0112-1","source":{"id":"https://openalex.org/S205663195","display_name":"Algorithms for Molecular Biology","issn_l":"1748-7188","issn":["1748-7188"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Algorithms for Molecular Biology","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://almob.biomedcentral.com/track/pdf/10.1186/s13015-017-0112-1","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5102865092","display_name":"Christopher Schr\u00f6der","orcid":"https://orcid.org/0000-0002-4483-8951"},"institutions":[{"id":"https://openalex.org/I4210119759","display_name":"Essen University Hospital","ror":"https://ror.org/02na8dn90","country_code":"DE","type":"funder","lineage":["https://openalex.org/I4210119759"]},{"id":"https://openalex.org/I62318514","display_name":"University of Duisburg-Essen","ror":"https://ror.org/04mz5ra38","country_code":"DE","type":"education","lineage":["https://openalex.org/I62318514"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Christopher Schr\u00f6der","raw_affiliation_strings":["Genome Informatics, Institute of Human Genetics, University of Duisburg-Essen, University Hospital Essen, Hufelandstr. 55, 45147 Essen, Germany","Genome Informatics, Institute of Human Genetics, University of Duisburg-Essen, University Hospital Essen, Hufelandstr. 55, 45147, Essen, Germany"],"affiliations":[{"raw_affiliation_string":"Genome Informatics, Institute of Human Genetics, University of Duisburg-Essen, University Hospital Essen, Hufelandstr. 55, 45147 Essen, Germany","institution_ids":["https://openalex.org/I4210119759","https://openalex.org/I62318514"]},{"raw_affiliation_string":"Genome Informatics, Institute of Human Genetics, University of Duisburg-Essen, University Hospital Essen, Hufelandstr. 55, 45147, Essen, Germany","institution_ids":["https://openalex.org/I62318514","https://openalex.org/I4210119759"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5059606670","display_name":"Sven Rahmann","orcid":"https://orcid.org/0000-0002-8536-6065"},"institutions":[{"id":"https://openalex.org/I4210119759","display_name":"Essen University Hospital","ror":"https://ror.org/02na8dn90","country_code":"DE","type":"funder","lineage":["https://openalex.org/I4210119759"]},{"id":"https://openalex.org/I62318514","display_name":"University of Duisburg-Essen","ror":"https://ror.org/04mz5ra38","country_code":"DE","type":"education","lineage":["https://openalex.org/I62318514"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Sven Rahmann","raw_affiliation_strings":["Genome Informatics, Institute of Human Genetics, University of Duisburg-Essen, University Hospital Essen, Hufelandstr. 55, 45147 Essen, Germany","Genome Informatics, Institute of Human Genetics, University of Duisburg-Essen, University Hospital Essen, Hufelandstr. 55, 45147, Essen, Germany"],"affiliations":[{"raw_affiliation_string":"Genome Informatics, Institute of Human Genetics, University of Duisburg-Essen, University Hospital Essen, Hufelandstr. 55, 45147 Essen, Germany","institution_ids":["https://openalex.org/I4210119759","https://openalex.org/I62318514"]},{"raw_affiliation_string":"Genome Informatics, Institute of Human Genetics, University of Duisburg-Essen, University Hospital Essen, Hufelandstr. 55, 45147, Essen, Germany","institution_ids":["https://openalex.org/I62318514","https://openalex.org/I4210119759"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5102865092"],"corresponding_institution_ids":["https://openalex.org/I4210119759","https://openalex.org/I62318514"],"apc_list":{"value":1490,"currency":"GBP","value_usd":1827},"apc_paid":{"value":1490,"currency":"GBP","value_usd":1827},"fwci":2.2865,"has_fulltext":true,"cited_by_count":26,"citation_normalized_percentile":{"value":0.91233107,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":91,"max":98},"biblio":{"volume":"12","issue":"1","first_page":"21","last_page":"21"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11269","display_name":"Algorithms and Data Compression","score":0.9782999753952026,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11269","display_name":"Algorithms and Data Compression","score":0.9782999753952026,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12964","display_name":"Diet, Metabolism, and Disease","score":0.972000002861023,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9415000081062317,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6004574298858643},{"id":"https://openalex.org/keywords/state","display_name":"State (computer science)","score":0.5743131637573242},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.5155408382415771},{"id":"https://openalex.org/keywords/beta","display_name":"BETA (programming language)","score":0.4646437168121338},{"id":"https://openalex.org/keywords/estimation","display_name":"Estimation","score":0.4504285454750061},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.43450862169265747},{"id":"https://openalex.org/keywords/estimation-theory","display_name":"Estimation theory","score":0.4210893511772156},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.08973798155784607},{"id":"https://openalex.org/keywords/programming-language","display_name":"Programming language","score":0.07732638716697693}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6004574298858643},{"id":"https://openalex.org/C48103436","wikidata":"https://www.wikidata.org/wiki/Q599031","display_name":"State (computer science)","level":2,"score":0.5743131637573242},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.5155408382415771},{"id":"https://openalex.org/C2776174256","wikidata":"https://www.wikidata.org/wiki/Q830842","display_name":"BETA (programming language)","level":2,"score":0.4646437168121338},{"id":"https://openalex.org/C96250715","wikidata":"https://www.wikidata.org/wiki/Q965330","display_name":"Estimation","level":2,"score":0.4504285454750061},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.43450862169265747},{"id":"https://openalex.org/C167928553","wikidata":"https://www.wikidata.org/wiki/Q1376021","display_name":"Estimation theory","level":2,"score":0.4210893511772156},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.08973798155784607},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.07732638716697693},{"id":"https://openalex.org/C201995342","wikidata":"https://www.wikidata.org/wiki/Q682496","display_name":"Systems engineering","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1186/s13015-017-0112-1","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13015-017-0112-1","pdf_url":"https://almob.biomedcentral.com/track/pdf/10.1186/s13015-017-0112-1","source":{"id":"https://openalex.org/S205663195","display_name":"Algorithms for Molecular Biology","issn_l":"1748-7188","issn":["1748-7188"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Algorithms for Molecular Biology","raw_type":"journal-article"},{"id":"pmid:28828033","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28828033","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Algorithms for molecular biology : AMB","raw_type":null},{"id":"pmh:oai:doaj.org/article:82da8ea0d5a64a62abaaf450e61e11a0","is_oa":true,"landing_page_url":"https://doaj.org/article/82da8ea0d5a64a62abaaf450e61e11a0","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Algorithms for Molecular Biology, Vol 12, Iss 1, Pp 1-12 (2017)","raw_type":"article"},{"id":"pmh:oai:europepmc.org:4459731","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5563068","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/s13015-017-0112-1","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13015-017-0112-1","pdf_url":"https://almob.biomedcentral.com/track/pdf/10.1186/s13015-017-0112-1","source":{"id":"https://openalex.org/S205663195","display_name":"Algorithms for Molecular Biology","issn_l":"1748-7188","issn":["1748-7188"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Algorithms for Molecular Biology","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1327134102","display_name":null,"funder_award_id":"Pe-2013-0012","funder_id":"https://openalex.org/F4320327916","funder_display_name":"Mercator Research Center Ruhr"},{"id":"https://openalex.org/G1640141467","display_name":null,"funder_award_id":"01KU1216","funder_id":"https://openalex.org/F4320321114","funder_display_name":"Bundesministerium f\u00fcr Bildung und Forschung"},{"id":"https://openalex.org/G352791218","display_name":null,"funder_award_id":"(BMBF)","funder_id":"https://openalex.org/F4320321114","funder_display_name":"Bundesministerium f\u00fcr Bildung und Forschung"},{"id":"https://openalex.org/G5168466499","display_name":null,"funder_award_id":"Project","funder_id":"https://openalex.org/F4320321114","funder_display_name":"Bundesministerium f\u00fcr Bildung und Forschung"},{"id":"https://openalex.org/G5421948593","display_name":null,"funder_award_id":"SFB 876 / C1","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G5523801029","display_name":null,"funder_award_id":"SFB 876","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G6052429835","display_name":null,"funder_award_id":"(DFG)","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G762232396","display_name":null,"funder_award_id":"Project","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"}],"funders":[{"id":"https://openalex.org/F4320320879","display_name":"Deutsche Forschungsgemeinschaft","ror":"https://ror.org/018mejw64"},{"id":"https://openalex.org/F4320321114","display_name":"Bundesministerium f\u00fcr Bildung und Forschung","ror":"https://ror.org/04pz7b180"},{"id":"https://openalex.org/F4320327916","display_name":"Mercator Research Center Ruhr","ror":"https://ror.org/04rbpat47"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2771671371.pdf","grobid_xml":"https://content.openalex.org/works/W2771671371.grobid-xml"},"referenced_works_count":11,"referenced_works":["https://openalex.org/W1773422510","https://openalex.org/W1981367467","https://openalex.org/W2022852240","https://openalex.org/W2040507896","https://openalex.org/W2049633694","https://openalex.org/W2063875001","https://openalex.org/W2104258917","https://openalex.org/W2140954822","https://openalex.org/W2142635246","https://openalex.org/W2169012810","https://openalex.org/W4255375128"],"related_works":["https://openalex.org/W2576994247","https://openalex.org/W2606891670","https://openalex.org/W2608353378","https://openalex.org/W4249206767","https://openalex.org/W2321604366","https://openalex.org/W2563559453","https://openalex.org/W2055361825","https://openalex.org/W2382330008","https://openalex.org/W2946946499","https://openalex.org/W1519970947"],"abstract_inverted_index":{"The":[0],"hybrid":[1],"algorithm":[2],"between":[3],"likelihood-based":[4],"component":[5],"un-mixing":[6],"and":[7,14],"moment-based":[8],"parameter":[9],"estimation":[10],"is":[11],"a":[12],"robust":[13],"efficient":[15],"method":[16,27],"for":[17],"beta":[18],"mixture":[19],"estimation.":[20],"We":[21],"provide":[22],"an":[23],"implementation":[24],"of":[25],"the":[26,34],"(\"betamix\")":[28],"as":[29],"open":[30],"source":[31],"software":[32],"under":[33],"MIT":[35],"license.":[36]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":3}],"updated_date":"2026-04-10T15:06:20.359241","created_date":"2025-10-10T00:00:00"}