{"id":"https://openalex.org/W2884922228","doi":"https://doi.org/10.1186/s12918-018-0600-z","title":"Extracting proteins involved in disease progression using temporally connected networks","display_name":"Extracting proteins involved in disease progression using temporally connected networks","publication_year":2018,"publication_date":"2018-07-25","ids":{"openalex":"https://openalex.org/W2884922228","doi":"https://doi.org/10.1186/s12918-018-0600-z","mag":"2884922228","pmid":"https://pubmed.ncbi.nlm.nih.gov/30045727"},"language":"en","primary_location":{"id":"doi:10.1186/s12918-018-0600-z","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12918-018-0600-z","pdf_url":"https://bmcsystbiol.biomedcentral.com/track/pdf/10.1186/s12918-018-0600-z","source":{"id":"https://openalex.org/S92363890","display_name":"BMC Systems Biology","issn_l":"1752-0509","issn":["1752-0509"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Systems Biology","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://bmcsystbiol.biomedcentral.com/track/pdf/10.1186/s12918-018-0600-z","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5077462208","display_name":"Rajat Anand","orcid":null},"institutions":[{"id":"https://openalex.org/I2801880299","display_name":"Translational Health Science and Technology Institute","ror":"https://ror.org/01qjqvr92","country_code":"IN","type":"government","lineage":["https://openalex.org/I2799351866","https://openalex.org/I2801880299","https://openalex.org/I4210134808"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Rajat Anand","raw_affiliation_strings":["Drug Discovery Research Centre, Translational Health Science and Technology Institute, NCR Biotech science cluster, 3rd milestone, Faridabad-Gurgaon Expressway, Faridabad, 121001, India"],"affiliations":[{"raw_affiliation_string":"Drug Discovery Research Centre, Translational Health Science and Technology Institute, NCR Biotech science cluster, 3rd milestone, Faridabad-Gurgaon Expressway, Faridabad, 121001, India","institution_ids":["https://openalex.org/I2801880299"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076905376","display_name":"Dipanka Tanu Sarmah","orcid":null},"institutions":[{"id":"https://openalex.org/I2801880299","display_name":"Translational Health Science and Technology Institute","ror":"https://ror.org/01qjqvr92","country_code":"IN","type":"government","lineage":["https://openalex.org/I2799351866","https://openalex.org/I2801880299","https://openalex.org/I4210134808"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Dipanka Tanu Sarmah","raw_affiliation_strings":["Drug Discovery Research Centre, Translational Health Science and Technology Institute, NCR Biotech science cluster, 3rd milestone, Faridabad-Gurgaon Expressway, Faridabad, 121001, India"],"affiliations":[{"raw_affiliation_string":"Drug Discovery Research Centre, Translational Health Science and Technology Institute, NCR Biotech science cluster, 3rd milestone, Faridabad-Gurgaon Expressway, Faridabad, 121001, India","institution_ids":["https://openalex.org/I2801880299"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5082491317","display_name":"Samrat Chatterjee","orcid":"https://orcid.org/0000-0002-5010-2799"},"institutions":[{"id":"https://openalex.org/I2801880299","display_name":"Translational Health Science and Technology Institute","ror":"https://ror.org/01qjqvr92","country_code":"IN","type":"government","lineage":["https://openalex.org/I2799351866","https://openalex.org/I2801880299","https://openalex.org/I4210134808"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Samrat Chatterjee","raw_affiliation_strings":["Drug Discovery Research Centre, Translational Health Science and Technology Institute, NCR Biotech science cluster, 3rd milestone, Faridabad-Gurgaon Expressway, Faridabad, 121001, India. samrat.chatterjee@thsti.res.in","Drug Discovery Research Centre, Translational Health Science and Technology Institute, NCR Biotech science cluster, 3rd milestone, Faridabad-Gurgaon Expressway, Faridabad, 121001, India"],"affiliations":[{"raw_affiliation_string":"Drug Discovery Research Centre, Translational Health Science and Technology Institute, NCR Biotech science cluster, 3rd milestone, Faridabad-Gurgaon Expressway, Faridabad, 121001, India. samrat.chatterjee@thsti.res.in","institution_ids":[]},{"raw_affiliation_string":"Drug Discovery Research Centre, Translational Health Science and Technology Institute, NCR Biotech science cluster, 3rd milestone, Faridabad-Gurgaon Expressway, Faridabad, 121001, India","institution_ids":["https://openalex.org/I2801880299"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5077462208"],"corresponding_institution_ids":["https://openalex.org/I2801880299"],"apc_list":null,"apc_paid":null,"fwci":0.2784,"has_fulltext":true,"cited_by_count":10,"citation_normalized_percentile":{"value":0.57279723,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":97},"biblio":{"volume":"12","issue":"1","first_page":"78","last_page":"78"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9969000220298767,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10836","display_name":"Metabolomics and Mass Spectrometry Studies","score":0.9957000017166138,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/microarray-analysis-techniques","display_name":"Microarray analysis techniques","score":0.5881179571151733},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5827431082725525},{"id":"https://openalex.org/keywords/systems-biology","display_name":"Systems biology","score":0.5675642490386963},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5254663228988647},{"id":"https://openalex.org/keywords/gene-regulatory-network","display_name":"Gene regulatory network","score":0.47467920184135437},{"id":"https://openalex.org/keywords/disease","display_name":"Disease","score":0.43256238102912903},{"id":"https://openalex.org/keywords/complex-disease","display_name":"Complex disease","score":0.4219772219657898},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.37985679507255554},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.3779495656490326},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.35070711374282837},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.3456544578075409},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.1627890169620514},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.1482865810394287},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.09064880013465881},{"id":"https://openalex.org/keywords/pathology","display_name":"Pathology","score":0.0779367983341217}],"concepts":[{"id":"https://openalex.org/C8415881","wikidata":"https://www.wikidata.org/wiki/Q6839217","display_name":"Microarray analysis techniques","level":4,"score":0.5881179571151733},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5827431082725525},{"id":"https://openalex.org/C152662350","wikidata":"https://www.wikidata.org/wiki/Q815297","display_name":"Systems biology","level":2,"score":0.5675642490386963},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5254663228988647},{"id":"https://openalex.org/C67339327","wikidata":"https://www.wikidata.org/wiki/Q1502576","display_name":"Gene regulatory network","level":4,"score":0.47467920184135437},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.43256238102912903},{"id":"https://openalex.org/C3018605307","wikidata":"https://www.wikidata.org/wiki/Q200779","display_name":"Complex disease","level":3,"score":0.4219772219657898},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.37985679507255554},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3779495656490326},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.35070711374282837},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.3456544578075409},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.1627890169620514},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1482865810394287},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.09064880013465881},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0779367983341217}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D060066","descriptor_name":"Protein Interaction Maps","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D060066","descriptor_name":"Protein Interaction Maps","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D060066","descriptor_name":"Protein Interaction Maps","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.1186/s12918-018-0600-z","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12918-018-0600-z","pdf_url":"https://bmcsystbiol.biomedcentral.com/track/pdf/10.1186/s12918-018-0600-z","source":{"id":"https://openalex.org/S92363890","display_name":"BMC Systems Biology","issn_l":"1752-0509","issn":["1752-0509"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Systems Biology","raw_type":"journal-article"},{"id":"pmid:30045727","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30045727","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC systems biology","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:6060549","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6060549","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Syst Biol","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:10ebadd2ebbe46c5b709ea8d706f6262","is_oa":true,"landing_page_url":"https://doaj.org/article/10ebadd2ebbe46c5b709ea8d706f6262","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Systems Biology, Vol 12, Iss 1, Pp 1-13 (2018)","raw_type":"article"},{"id":"pmh:oai:europepmc.org:5022366","is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC6060549","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/s12918-018-0600-z","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12918-018-0600-z","pdf_url":"https://bmcsystbiol.biomedcentral.com/track/pdf/10.1186/s12918-018-0600-z","source":{"id":"https://openalex.org/S92363890","display_name":"BMC Systems Biology","issn_l":"1752-0509","issn":["1752-0509"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Systems Biology","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1163538233","display_name":null,"funder_award_id":"25 (0258)/16/EMR-II.","funder_id":"https://openalex.org/F4320320721","funder_display_name":"Council of Scientific and Industrial Research, India"}],"funders":[{"id":"https://openalex.org/F4320320721","display_name":"Council of Scientific and Industrial Research, India","ror":"https://ror.org/021wm7p51"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2884922228.pdf","grobid_xml":"https://content.openalex.org/works/W2884922228.grobid-xml"},"referenced_works_count":23,"referenced_works":["https://openalex.org/W1931400479","https://openalex.org/W1967053372","https://openalex.org/W1969385456","https://openalex.org/W1976969006","https://openalex.org/W1990018359","https://openalex.org/W2025356299","https://openalex.org/W2044057392","https://openalex.org/W2055706365","https://openalex.org/W2058596530","https://openalex.org/W2068612365","https://openalex.org/W2072589422","https://openalex.org/W2081490620","https://openalex.org/W2101420429","https://openalex.org/W2105924489","https://openalex.org/W2109970232","https://openalex.org/W2113654344","https://openalex.org/W2130410032","https://openalex.org/W2154431984","https://openalex.org/W2156779720","https://openalex.org/W2168775836","https://openalex.org/W2180749449","https://openalex.org/W2260176602","https://openalex.org/W2609388058"],"related_works":["https://openalex.org/W2135896045","https://openalex.org/W2156421048","https://openalex.org/W2884256268","https://openalex.org/W1982897783","https://openalex.org/W2171763327","https://openalex.org/W3108451992","https://openalex.org/W2031892952","https://openalex.org/W1993417849","https://openalex.org/W4285211287","https://openalex.org/W2593260643"],"abstract_inverted_index":{"The":[0],"critical":[1],"proteins":[2],"identified":[3],"from":[4],"algorithms":[5],"can":[6],"be":[7],"hypothesized":[8],"to":[9],"play":[10],"important":[11],"role":[12],"in":[13],"temporal":[14],"progression":[15],"of":[16],"the":[17],"data.":[18]},"counts_by_year":[{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":3},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1}],"updated_date":"2026-03-20T23:20:44.827607","created_date":"2025-10-10T00:00:00"}