{"id":"https://openalex.org/W2775879243","doi":"https://doi.org/10.1186/s12918-017-0503-4","title":"Identification of natural antimicrobial peptides from bacteria through metagenomic and metatranscriptomic analysis of high-throughput transcriptome data of Taiwanese oolong teas","display_name":"Identification of natural antimicrobial peptides from bacteria through metagenomic and metatranscriptomic analysis of high-throughput transcriptome data of Taiwanese oolong teas","publication_year":2017,"publication_date":"2017-12-01","ids":{"openalex":"https://openalex.org/W2775879243","doi":"https://doi.org/10.1186/s12918-017-0503-4","mag":"2775879243","pmid":"https://pubmed.ncbi.nlm.nih.gov/29322917"},"language":"en","primary_location":{"id":"doi:10.1186/s12918-017-0503-4","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12918-017-0503-4","pdf_url":"https://link.springer.com/content/pdf/10.1186/s12918-017-0503-4.pdf","source":{"id":"https://openalex.org/S92363890","display_name":"BMC Systems Biology","issn_l":"1752-0509","issn":["1752-0509"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Systems Biology","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://link.springer.com/content/pdf/10.1186/s12918-017-0503-4.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101875147","display_name":"Kai\u2010Yao Huang","orcid":"https://orcid.org/0000-0001-9855-1035"},"institutions":[{"id":"https://openalex.org/I2802753785","display_name":"Mackay Memorial Hospital","ror":"https://ror.org/015b6az38","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I2802753785"]},{"id":"https://openalex.org/I99908691","display_name":"Yuan Ze University","ror":"https://ror.org/01fv1ds98","country_code":"TW","type":"education","lineage":["https://openalex.org/I99908691"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Kai-Yao Huang","raw_affiliation_strings":["Department of Computer Science and Engineering, Yuan Ze University, Taoyuan City, 320, Taiwan","Department of Medical Research, Hsinchu Mackay Memorial Hospital, Hsinchu City, 300, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science and Engineering, Yuan Ze University, Taoyuan City, 320, Taiwan","institution_ids":["https://openalex.org/I99908691"]},{"raw_affiliation_string":"Department of Medical Research, Hsinchu Mackay Memorial Hospital, Hsinchu City, 300, Taiwan","institution_ids":["https://openalex.org/I2802753785"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008637858","display_name":"Tzu\u2010Hao Chang","orcid":"https://orcid.org/0000-0001-7011-3754"},"institutions":[{"id":"https://openalex.org/I47519274","display_name":"Taipei Medical University","ror":"https://ror.org/05031qk94","country_code":"TW","type":"education","lineage":["https://openalex.org/I47519274"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Tzu-Hao Chang","raw_affiliation_strings":["Graduate Institute of Biomedical Informatics, Taipei Medical University, Taipei, 110, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graduate Institute of Biomedical Informatics, Taipei Medical University, Taipei, 110, Taiwan","institution_ids":["https://openalex.org/I47519274"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062800975","display_name":"Jhih-Hua Jhong","orcid":"https://orcid.org/0000-0001-6158-5207"},"institutions":[{"id":"https://openalex.org/I99908691","display_name":"Yuan Ze University","ror":"https://ror.org/01fv1ds98","country_code":"TW","type":"education","lineage":["https://openalex.org/I99908691"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Jhih-Hua Jhong","raw_affiliation_strings":["Department of Computer Science and Engineering, Yuan Ze University, Taoyuan City, 320, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science and Engineering, Yuan Ze University, Taoyuan City, 320, Taiwan","institution_ids":["https://openalex.org/I99908691"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111554917","display_name":"Yu-Hsiang Chi","orcid":null},"institutions":[{"id":"https://openalex.org/I99908691","display_name":"Yuan Ze University","ror":"https://ror.org/01fv1ds98","country_code":"TW","type":"education","lineage":["https://openalex.org/I99908691"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Yu-Hsiang Chi","raw_affiliation_strings":["Department of Computer Science and Engineering, Yuan Ze University, Taoyuan City, 320, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science and Engineering, Yuan Ze University, Taoyuan City, 320, Taiwan","institution_ids":["https://openalex.org/I99908691"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069831663","display_name":"Wen-Chi Li","orcid":null},"institutions":[{"id":"https://openalex.org/I99908691","display_name":"Yuan Ze University","ror":"https://ror.org/01fv1ds98","country_code":"TW","type":"education","lineage":["https://openalex.org/I99908691"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Wen-Chi Li","raw_affiliation_strings":["Department of Computer Science and Engineering, Yuan Ze University, Taoyuan City, 320, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science and Engineering, Yuan Ze University, Taoyuan City, 320, Taiwan","institution_ids":["https://openalex.org/I99908691"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083680938","display_name":"Chien\u2010Lung Chan","orcid":"https://orcid.org/0000-0002-7486-7075"},"institutions":[{"id":"https://openalex.org/I99908691","display_name":"Yuan Ze University","ror":"https://ror.org/01fv1ds98","country_code":"TW","type":"education","lineage":["https://openalex.org/I99908691"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Chien-Lung Chan","raw_affiliation_strings":["Department of Information Management, Yuan Ze University, Taoyuan City, 320, Taiwan","Innovation Center for Big Data and Digital Convergence, Yuan Ze University, Taoyuan, city, 320, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Information Management, Yuan Ze University, Taoyuan City, 320, Taiwan","institution_ids":["https://openalex.org/I99908691"]},{"raw_affiliation_string":"Innovation Center for Big Data and Digital Convergence, Yuan Ze University, Taoyuan, city, 320, Taiwan","institution_ids":["https://openalex.org/I99908691"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044292096","display_name":"K. Robert Lai","orcid":"https://orcid.org/0000-0002-3365-3927"},"institutions":[{"id":"https://openalex.org/I99908691","display_name":"Yuan Ze University","ror":"https://ror.org/01fv1ds98","country_code":"TW","type":"education","lineage":["https://openalex.org/I99908691"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"K. Robert Lai","raw_affiliation_strings":["Department of Computer Science and Engineering, Yuan Ze University, Taoyuan City, 320, Taiwan","Innovation Center for Big Data and Digital Convergence, Yuan Ze University, Taoyuan, city, 320, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science and Engineering, Yuan Ze University, Taoyuan City, 320, Taiwan","institution_ids":["https://openalex.org/I99908691"]},{"raw_affiliation_string":"Innovation Center for Big Data and Digital Convergence, Yuan Ze University, Taoyuan, city, 320, Taiwan","institution_ids":["https://openalex.org/I99908691"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5045675277","display_name":"Tzong-Yi Lee","orcid":"https://orcid.org/0000-0001-8475-7868"},"institutions":[{"id":"https://openalex.org/I99908691","display_name":"Yuan Ze University","ror":"https://ror.org/01fv1ds98","country_code":"TW","type":"education","lineage":["https://openalex.org/I99908691"]}],"countries":["TW"],"is_corresponding":true,"raw_author_name":"Tzong-Yi Lee","raw_affiliation_strings":["Department of Computer Science and Engineering, Yuan Ze University, Taoyuan City, 320, Taiwan. francis@saturn.yzu.edu.tw","Innovation Center for Big Data and Digital Convergence, Yuan Ze University, Taoyuan, city, 320, Taiwan. francis@saturn.yzu.edu.tw","Department of Computer Science and Engineering, Yuan Ze University, Taoyuan City, 320, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science and Engineering, Yuan Ze University, Taoyuan City, 320, Taiwan. francis@saturn.yzu.edu.tw","institution_ids":["https://openalex.org/I99908691"]},{"raw_affiliation_string":"Innovation Center for Big Data and Digital Convergence, Yuan Ze University, Taoyuan, city, 320, Taiwan. francis@saturn.yzu.edu.tw","institution_ids":["https://openalex.org/I99908691"]},{"raw_affiliation_string":"Department of Computer Science and Engineering, Yuan Ze University, Taoyuan City, 320, Taiwan","institution_ids":["https://openalex.org/I99908691"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5045675277"],"corresponding_institution_ids":["https://openalex.org/I99908691"],"apc_list":{"value":2290,"currency":"USD","value_usd":2290},"apc_paid":{"value":2290,"currency":"USD","value_usd":2290},"fwci":1.7202,"has_fulltext":true,"cited_by_count":32,"citation_normalized_percentile":{"value":0.84185447,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":98},"biblio":{"volume":"11","issue":"S7","first_page":"131","last_page":"131"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11411","display_name":"Tea Polyphenols and Effects","score":0.40860000252723694,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11411","display_name":"Tea Polyphenols and Effects","score":0.40860000252723694,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11103","display_name":"Antimicrobial Peptides and Activities","score":0.23019999265670776,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10141","display_name":"Probiotics and Fermented Foods","score":0.08529999852180481,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/metagenomics","display_name":"Metagenomics","score":0.8401433825492859},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.7703883647918701},{"id":"https://openalex.org/keywords/transcriptome","display_name":"Transcriptome","score":0.6058566570281982},{"id":"https://openalex.org/keywords/antimicrobial-peptides","display_name":"Antimicrobial peptides","score":0.5487268567085266},{"id":"https://openalex.org/keywords/microbiome","display_name":"Microbiome","score":0.47765910625457764},{"id":"https://openalex.org/keywords/bacteria","display_name":"Bacteria","score":0.4409201145172119},{"id":"https://openalex.org/keywords/microbiology","display_name":"Microbiology","score":0.4072093367576599},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.3669787049293518},{"id":"https://openalex.org/keywords/antimicrobial","display_name":"Antimicrobial","score":0.32506006956100464},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.2869495451450348},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.2077343761920929},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.12345370650291443}],"concepts":[{"id":"https://openalex.org/C15151743","wikidata":"https://www.wikidata.org/wiki/Q903778","display_name":"Metagenomics","level":3,"score":0.8401433825492859},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7703883647918701},{"id":"https://openalex.org/C162317418","wikidata":"https://www.wikidata.org/wiki/Q252857","display_name":"Transcriptome","level":4,"score":0.6058566570281982},{"id":"https://openalex.org/C540938839","wikidata":"https://www.wikidata.org/wiki/Q1201508","display_name":"Antimicrobial peptides","level":3,"score":0.5487268567085266},{"id":"https://openalex.org/C143121216","wikidata":"https://www.wikidata.org/wiki/Q1330402","display_name":"Microbiome","level":2,"score":0.47765910625457764},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.4409201145172119},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.4072093367576599},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3669787049293518},{"id":"https://openalex.org/C4937899","wikidata":"https://www.wikidata.org/wiki/Q68541106","display_name":"Antimicrobial","level":2,"score":0.32506006956100464},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2869495451450348},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2077343761920929},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.12345370650291443}],"mesh":[{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012336","descriptor_name":"RNA, Ribosomal, 16S","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012336","descriptor_name":"RNA, Ribosomal, 16S","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012336","descriptor_name":"RNA, Ribosomal, 16S","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D013662","descriptor_name":"Tea","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D013662","descriptor_name":"Tea","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D013662","descriptor_name":"Tea","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D017423","descriptor_name":"Sequence Analysis, RNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017423","descriptor_name":"Sequence Analysis, RNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017423","descriptor_name":"Sequence Analysis, RNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D023181","descriptor_name":"Antimicrobial Cationic Peptides","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D023181","descriptor_name":"Antimicrobial Cationic Peptides","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D023181","descriptor_name":"Antimicrobial Cationic Peptides","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D056186","descriptor_name":"Metagenomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D056186","descriptor_name":"Metagenomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D056186","descriptor_name":"Metagenomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D059014","descriptor_name":"High-Throughput Nucleotide Sequencing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059014","descriptor_name":"High-Throughput Nucleotide Sequencing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059014","descriptor_name":"High-Throughput Nucleotide Sequencing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1186/s12918-017-0503-4","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12918-017-0503-4","pdf_url":"https://link.springer.com/content/pdf/10.1186/s12918-017-0503-4.pdf","source":{"id":"https://openalex.org/S92363890","display_name":"BMC Systems Biology","issn_l":"1752-0509","issn":["1752-0509"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Systems Biology","raw_type":"journal-article"},{"id":"pmid:29322917","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29322917","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC systems biology","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:5763296","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5763296","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Syst Biol","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:41f63b76673845f3918b3c27cbd66024","is_oa":false,"landing_page_url":"https://doaj.org/article/41f63b76673845f3918b3c27cbd66024","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Systems Biology, Vol 11, Iss S7, Pp 29-44 (2017)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/s12918-017-0503-4","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12918-017-0503-4","pdf_url":"https://link.springer.com/content/pdf/10.1186/s12918-017-0503-4.pdf","source":{"id":"https://openalex.org/S92363890","display_name":"BMC Systems Biology","issn_l":"1752-0509","issn":["1752-0509"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Systems Biology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Clean water and sanitation","score":0.4099999964237213,"id":"https://metadata.un.org/sdg/6"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2775879243.pdf","grobid_xml":"https://content.openalex.org/works/W2775879243.grobid-xml"},"referenced_works_count":47,"referenced_works":["https://openalex.org/W1488730707","https://openalex.org/W1538259875","https://openalex.org/W1742789539","https://openalex.org/W1934236512","https://openalex.org/W1969018883","https://openalex.org/W1978458547","https://openalex.org/W1992003822","https://openalex.org/W1999574084","https://openalex.org/W2006311180","https://openalex.org/W2008683828","https://openalex.org/W2011657487","https://openalex.org/W2015490529","https://openalex.org/W2031789714","https://openalex.org/W2032230795","https://openalex.org/W2041404167","https://openalex.org/W2043390594","https://openalex.org/W2063856799","https://openalex.org/W2067402644","https://openalex.org/W2067468162","https://openalex.org/W2068489600","https://openalex.org/W2073332363","https://openalex.org/W2078527867","https://openalex.org/W2087292184","https://openalex.org/W2088833470","https://openalex.org/W2095854550","https://openalex.org/W2107097628","https://openalex.org/W2114516201","https://openalex.org/W2119311989","https://openalex.org/W2121211805","https://openalex.org/W2123060905","https://openalex.org/W2125826054","https://openalex.org/W2132303768","https://openalex.org/W2133096092","https://openalex.org/W2133790733","https://openalex.org/W2140226147","https://openalex.org/W2150926065","https://openalex.org/W2158217645","https://openalex.org/W2163316049","https://openalex.org/W2170551349","https://openalex.org/W2175270296","https://openalex.org/W2222445509","https://openalex.org/W2227172168","https://openalex.org/W2299570743","https://openalex.org/W2323986844","https://openalex.org/W2409427249","https://openalex.org/W4246905938","https://openalex.org/W6678274143"],"related_works":["https://openalex.org/W3139084279","https://openalex.org/W1973192249","https://openalex.org/W2354039930","https://openalex.org/W2044458410","https://openalex.org/W4375855538","https://openalex.org/W2388831772","https://openalex.org/W3087020980","https://openalex.org/W2511368942","https://openalex.org/W2107525095","https://openalex.org/W4211241221"],"abstract_inverted_index":{"BACKGROUND:":[0],"Anti-microbial":[1],"peptides":[2],"(AMPs),":[3],"naturally":[4],"encoded":[5],"by":[6],"genes":[7],"and":[8,22,31,55,75,97,102,108,118,147,156,174,186,193,211,221,225,256,277,297,314,325],"generally":[9],"containing":[10],"12-100":[11],"amino":[12],"acids,":[13],"are":[14],"crucial":[15],"components":[16],"of":[17,39,47,60,77,133,151,196,202,290,312,323],"the":[18,25,36,44,58,73,120,131,149,154,168,264,310,321],"innate":[19],"immune":[20,145],"system":[21],"can":[23],"protect":[24],"host":[26],"from":[27,92],"various":[28],"pathogenic":[29],"bacteria":[30,266,327],"viruses.":[32],"In":[33,111],"recent":[34],"years,":[35],"widespread":[37],"use":[38],"antibiotics":[40],"has":[41,63,84],"resulted":[42],"in":[43,71,125,136,160,328],"rapid":[45],"growth":[46],"antibiotic-resistant":[48],"microorganisms":[49],"that":[50,231,263,309],"often":[51],"induce":[52],"critical":[53],"infection":[54],"pathogenesis.":[56],"Recently,":[57],"advent":[59],"high-throughput":[61,197],"technologies":[62],"led":[64],"molecular":[65],"biology":[66],"into":[67],"a":[68,179],"data":[69],"surge":[70],"both":[72],"amount":[74],"scope":[76],"data.":[78,199],"For":[79],"instance,":[80],"next-generation":[81],"sequencing":[82,90],"technology":[83],"been":[85],"applied":[86],"to":[87,99,183,217,284,304],"generate":[88],"large-scale":[89],"reads":[91,300],"foods,":[93],"water,":[94],"soil,":[95],"air,":[96],"specimens":[98],"identify":[100,184],"microbiota":[101],"their":[103,157,187],"functions":[104,158],"based":[105,190],"on":[106,191],"metagenomics":[107,192],"metatranscriptomics,":[109],"respectively.":[110],"addition,":[112],"oolong":[113,134,161,172,203,330],"tea":[114,124,135,162,234,249,270,331],"is":[115,119,317],"partially":[116],"fermented":[117],"most":[121,243],"widely":[122],"produced":[123],"Taiwan.":[126],"Many":[127],"studies":[128],"have":[129],"shown":[130],"benefits":[132],"inhibiting":[137],"obesity,":[138],"reducing":[139],"dental":[140],"plaque":[141],"deposition,":[142],"antagonizing":[143],"allergic":[144],"responses,":[146],"alleviating":[148],"effects":[150],"aging.":[152],"However,":[153],"microbes":[155],"present":[159],"remain":[163],"unknown.":[164],"RESULTS:":[165],"To":[166],"understand":[167],"relationship":[169],"between":[170],"Taiwanese":[171,329],"teas":[173,204],"bacterial":[175,237,245],"communities,":[176],"we":[177],"designed":[178],"novel":[180],"bioinformatics":[181],"scheme":[182],"AMPs":[185,316],"functional":[188,286],"types":[189,201,250,271],"metatranscriptomic":[194],"analysis":[195,228,260],"transcriptome":[198],"Four":[200],"(Dayuling":[205],"tea,":[206,208,210],"Alishan":[207],"Jinxuan":[209],"Oriental":[212,232],"Beauty":[213,233],"tea)":[214],"were":[215,251,272,282],"subjected":[216,283],"16S":[218],"ribosomal":[219],"DNA":[220],"total":[222,289],"RNA":[223],"extraction":[224],"sequencing.":[226],"Metagenomics":[227],"results":[229,261],"revealed":[230,262],"exhibited":[235],"greater":[236],"diversity":[238],"than":[239],"other":[240],"teas.":[241],"The":[242],"common":[244],"families":[246],"across":[247,268],"all":[248,269],"Bacteroidaceae":[252],"(21.7%),":[253],"Veillonellaceae":[254],"(22%),":[255],"Fusobacteriaceae":[257],"(12.3%).":[258],"Metatranscriptomics":[259],"dominant":[265],"species":[267],"Escherichia":[273],"coli,":[274],"Bacillus":[275],"subtilis,":[276],"Chryseobacterium":[278],"sp.":[279],"StRB126,":[280],"which":[281],"further":[285],"analysis.":[287],"A":[288],"8194":[291],"(6.5%),":[292],"26,220":[293],"(6.1%),":[294],"5703":[295],"(5.8%),":[296],"106,183":[298],"(7.8%)":[299],"could":[301],"be":[302],"mapped":[303],"AMPs.":[305],"CONCLUSION:":[306],"We":[307],"found":[308],"distribution":[311,322],"anti-gram-positive":[313],"anti-gram-negative":[315],"highly":[318],"correlated":[319],"with":[320],"gram-positive":[324],"gram-negative":[326],"samples.":[332]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":2}],"updated_date":"2026-08-11T07:18:39.950985","created_date":"2025-10-10T00:00:00"}