{"id":"https://openalex.org/W2773435160","doi":"https://doi.org/10.1186/s12918-017-0475-4","title":"Mining significant high utility gene regulation sequential patterns","display_name":"Mining significant high utility gene regulation sequential patterns","publication_year":2017,"publication_date":"2017-12-01","ids":{"openalex":"https://openalex.org/W2773435160","doi":"https://doi.org/10.1186/s12918-017-0475-4","mag":"2773435160","pmid":"https://pubmed.ncbi.nlm.nih.gov/29297335"},"language":"en","primary_location":{"id":"doi:10.1186/s12918-017-0475-4","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12918-017-0475-4","pdf_url":"https://bmcsystbiol.biomedcentral.com/track/pdf/10.1186/s12918-017-0475-4","source":{"id":"https://openalex.org/S92363890","display_name":"BMC Systems Biology","issn_l":"1752-0509","issn":["1752-0509"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Systems Biology","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://bmcsystbiol.biomedcentral.com/track/pdf/10.1186/s12918-017-0475-4","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5037298220","display_name":"Morteza Zihayat","orcid":"https://orcid.org/0000-0002-1144-7364"},"institutions":[{"id":"https://openalex.org/I530967","display_name":"Toronto Metropolitan University","ror":"https://ror.org/05g13zd79","country_code":"CA","type":"education","lineage":["https://openalex.org/I530967"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"Morteza Zihayat","raw_affiliation_strings":["Ted Rogers School of Information Technology Management, Ryerson University, Bay Street, Toronto, Canada. mzihayat@ryerson.ca","Ted Rogers School of Information Technology Management, Ryerson University, Bay Street, Toronto, Canada"],"affiliations":[{"raw_affiliation_string":"Ted Rogers School of Information Technology Management, Ryerson University, Bay Street, Toronto, Canada. mzihayat@ryerson.ca","institution_ids":[]},{"raw_affiliation_string":"Ted Rogers School of Information Technology Management, Ryerson University, Bay Street, Toronto, Canada","institution_ids":["https://openalex.org/I530967"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014081539","display_name":"Heidar Davoudi","orcid":"https://orcid.org/0000-0002-9603-9625"},"institutions":[{"id":"https://openalex.org/I192455969","display_name":"York University","ror":"https://ror.org/05fq50484","country_code":"CA","type":"education","lineage":["https://openalex.org/I192455969"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Heidar Davoudi","raw_affiliation_strings":["Department of Electrical Engineering and Computer Science, York University, Keele Street, Toronto, Canada"],"affiliations":[{"raw_affiliation_string":"Department of Electrical Engineering and Computer Science, York University, Keele Street, Toronto, Canada","institution_ids":["https://openalex.org/I192455969"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5009394818","display_name":"Aijun An","orcid":"https://orcid.org/0000-0003-1765-5751"},"institutions":[{"id":"https://openalex.org/I192455969","display_name":"York University","ror":"https://ror.org/05fq50484","country_code":"CA","type":"education","lineage":["https://openalex.org/I192455969"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Aijun An","raw_affiliation_strings":["Department of Electrical Engineering and Computer Science, York University, Keele Street, Toronto, Canada"],"affiliations":[{"raw_affiliation_string":"Department of Electrical Engineering and Computer Science, York University, Keele Street, Toronto, Canada","institution_ids":["https://openalex.org/I192455969"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5037298220"],"corresponding_institution_ids":["https://openalex.org/I530967"],"apc_list":null,"apc_paid":null,"fwci":6.576,"has_fulltext":true,"cited_by_count":52,"citation_normalized_percentile":{"value":0.96950341,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"11","issue":"S6","first_page":"109","last_page":"109"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10538","display_name":"Data Mining Algorithms and Applications","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/1710","display_name":"Information Systems"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10538","display_name":"Data Mining Algorithms and Applications","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/1710","display_name":"Information Systems"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11975","display_name":"Evolutionary Algorithms and Applications","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9901999831199646,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/systems-biology","display_name":"Systems biology","score":0.6575577259063721},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.6255781650543213},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.4969046413898468},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.4783075153827667},{"id":"https://openalex.org/keywords/gene-regulatory-network","display_name":"Gene regulatory network","score":0.4763379693031311},{"id":"https://openalex.org/keywords/regulation-of-gene-expression","display_name":"Regulation of gene expression","score":0.4559025466442108},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.3959689438343048},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.3343578577041626},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.2541242837905884}],"concepts":[{"id":"https://openalex.org/C152662350","wikidata":"https://www.wikidata.org/wiki/Q815297","display_name":"Systems biology","level":2,"score":0.6575577259063721},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.6255781650543213},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4969046413898468},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.4783075153827667},{"id":"https://openalex.org/C67339327","wikidata":"https://www.wikidata.org/wiki/Q1502576","display_name":"Gene regulatory network","level":4,"score":0.4763379693031311},{"id":"https://openalex.org/C165864922","wikidata":"https://www.wikidata.org/wiki/Q411391","display_name":"Regulation of gene expression","level":3,"score":0.4559025466442108},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3959689438343048},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3343578577041626},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.2541242837905884}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010363","descriptor_name":"Pattern Recognition, Automated","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010363","descriptor_name":"Pattern Recognition, Automated","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010363","descriptor_name":"Pattern Recognition, Automated","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010363","descriptor_name":"Pattern Recognition, Automated","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057225","descriptor_name":"Data Mining","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D057225","descriptor_name":"Data Mining","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D057225","descriptor_name":"Data Mining","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D057225","descriptor_name":"Data Mining","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1186/s12918-017-0475-4","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12918-017-0475-4","pdf_url":"https://bmcsystbiol.biomedcentral.com/track/pdf/10.1186/s12918-017-0475-4","source":{"id":"https://openalex.org/S92363890","display_name":"BMC Systems Biology","issn_l":"1752-0509","issn":["1752-0509"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Systems Biology","raw_type":"journal-article"},{"id":"pmid:29297335","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29297335","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC systems biology","raw_type":null},{"id":"pmh:oai:doaj.org/article:fbf3dcff27ed4a418dc0b735ca6d2bd8","is_oa":true,"landing_page_url":"https://doaj.org/article/fbf3dcff27ed4a418dc0b735ca6d2bd8","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Systems Biology, Vol 11, Iss S6, Pp 1-14 (2017)","raw_type":"article"},{"id":"pmh:oai:europepmc.org:4668006","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5751562","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/s12918-017-0475-4","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12918-017-0475-4","pdf_url":"https://bmcsystbiol.biomedcentral.com/track/pdf/10.1186/s12918-017-0475-4","source":{"id":"https://openalex.org/S92363890","display_name":"BMC Systems Biology","issn_l":"1752-0509","issn":["1752-0509"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Systems Biology","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1304196372","display_name":null,"funder_award_id":"Program","funder_id":"https://openalex.org/F4320334593","funder_display_name":"Natural Sciences and Engineering Research Council of Canada"},{"id":"https://openalex.org/G2165548363","display_name":null,"funder_award_id":"Canada","funder_id":"https://openalex.org/F4320334593","funder_display_name":"Natural Sciences and Engineering Research Council of Canada"},{"id":"https://openalex.org/G2686240464","display_name":null,"funder_award_id":"NSERC CRD","funder_id":"https://openalex.org/F4320334593","funder_display_name":"Natural Sciences and Engineering Research Council of Canada"},{"id":"https://openalex.org/G8284766523","display_name":null,"funder_award_id":"(NSERC)","funder_id":"https://openalex.org/F4320334593","funder_display_name":"Natural Sciences and Engineering Research Council of Canada"}],"funders":[{"id":"https://openalex.org/F4320334593","display_name":"Natural Sciences and Engineering Research Council of Canada","ror":"https://ror.org/01h531d29"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2773435160.pdf","grobid_xml":"https://content.openalex.org/works/W2773435160.grobid-xml"},"referenced_works_count":39,"referenced_works":["https://openalex.org/W74439177","https://openalex.org/W201058601","https://openalex.org/W1504401263","https://openalex.org/W1556480481","https://openalex.org/W1608194207","https://openalex.org/W1641039719","https://openalex.org/W1983765024","https://openalex.org/W1990800901","https://openalex.org/W1999192179","https://openalex.org/W2000722665","https://openalex.org/W2009274826","https://openalex.org/W2015045861","https://openalex.org/W2049785083","https://openalex.org/W2066669827","https://openalex.org/W2068383400","https://openalex.org/W2071242348","https://openalex.org/W2099398039","https://openalex.org/W2115274736","https://openalex.org/W2120819598","https://openalex.org/W2124001239","https://openalex.org/W2138073318","https://openalex.org/W2139218243","https://openalex.org/W2143041118","https://openalex.org/W2144309138","https://openalex.org/W2147741644","https://openalex.org/W2153487450","https://openalex.org/W2158454296","https://openalex.org/W2161637667","https://openalex.org/W2168196587","https://openalex.org/W2329285245","https://openalex.org/W2365707302","https://openalex.org/W2506047819","https://openalex.org/W2575204312","https://openalex.org/W2585472988","https://openalex.org/W2604199453","https://openalex.org/W2913376378","https://openalex.org/W2914335078","https://openalex.org/W4234859835","https://openalex.org/W4248949446"],"related_works":["https://openalex.org/W5284979","https://openalex.org/W2949927938","https://openalex.org/W2135896045","https://openalex.org/W2010571965","https://openalex.org/W2032799661","https://openalex.org/W4245853730","https://openalex.org/W2002709996","https://openalex.org/W2884256268","https://openalex.org/W2131025197","https://openalex.org/W3128451840"],"abstract_inverted_index":{"In":[0],"this":[1,79],"study,":[2],"the":[3,24,51,60,74,81],"proposed":[4,28,61],"methods":[5,29],"were":[6,42],"evaluated":[7],"on":[8],"a":[9,63],"publicly":[10],"available":[11],"time":[12],"course":[13],"microarray":[14],"dataset.":[15],"The":[16],"experimental":[17],"results":[18],"show":[19],"higher":[20],"accuracies":[21],"compared":[22],"to":[23,68],"baseline":[25],"methods.":[26],"Our":[27],"found":[30],"that":[31],"several":[32],"new":[33],"gene":[34,88],"regulation":[35,89],"sequential":[36,90],"patterns":[37,41],"involved":[38],"in":[39],"such":[40],"useful":[43],"for":[44,84],"biologists":[45],"and":[46],"provided":[47],"further":[48],"insights":[49],"into":[50],"mechanisms":[52],"underpinning":[53],"biological":[54],"processes.":[55],"To":[56,73],"effectively":[57],"work":[58],"with":[59],"method,":[62],"web":[64],"interface":[65],"is":[66,80],"developed":[67],"our":[69,77],"system":[70],"using":[71],"Java.":[72],"best":[75],"of":[76],"knowledge,":[78],"first":[82],"demonstration":[83],"significant":[85],"high":[86],"utility":[87],"pattern":[91],"discovery.":[92]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":10},{"year":2022,"cited_by_count":14},{"year":2021,"cited_by_count":8},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":9},{"year":2018,"cited_by_count":1}],"updated_date":"2026-04-12T07:58:50.170612","created_date":"2025-10-10T00:00:00"}