{"id":"https://openalex.org/W2757839622","doi":"https://doi.org/10.1186/s12918-017-0454-9","title":"Bayesian network model for identification of pathways by integrating protein interaction with genetic interaction data","display_name":"Bayesian network model for identification of pathways by integrating protein interaction with genetic interaction data","publication_year":2017,"publication_date":"2017-09-01","ids":{"openalex":"https://openalex.org/W2757839622","doi":"https://doi.org/10.1186/s12918-017-0454-9","mag":"2757839622","pmid":"https://pubmed.ncbi.nlm.nih.gov/28950903"},"language":"en","primary_location":{"id":"doi:10.1186/s12918-017-0454-9","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12918-017-0454-9","pdf_url":"https://bmcsystbiol.biomedcentral.com/track/pdf/10.1186/s12918-017-0454-9","source":{"id":"https://openalex.org/S92363890","display_name":"BMC Systems Biology","issn_l":"1752-0509","issn":["1752-0509"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Systems Biology","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://bmcsystbiol.biomedcentral.com/track/pdf/10.1186/s12918-017-0454-9","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5085489027","display_name":"Changhe Fu","orcid":null},"institutions":[{"id":"https://openalex.org/I32399674","display_name":"Shenyang Normal University","ror":"https://ror.org/05cdfgm80","country_code":"CN","type":"education","lineage":["https://openalex.org/I32399674"]},{"id":"https://openalex.org/I4610292","display_name":"Xiangtan University","ror":"https://ror.org/00xsfaz62","country_code":"CN","type":"education","lineage":["https://openalex.org/I4610292"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Changhe Fu","raw_affiliation_strings":["School of Mathematics and Computational Science, Xiangtan University, Xiangtan, 411105, China. fuch@synu.edu.cn","School of Mathematics and System Science, Shenyang Normal University, Shenyang, 110034, China. fuch@synu.edu.cn","School of Mathematics and Computational Science, Xiangtan University, Xiangtan, 411105, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Mathematics and Computational Science, Xiangtan University, Xiangtan, 411105, China. fuch@synu.edu.cn","institution_ids":["https://openalex.org/I4610292"]},{"raw_affiliation_string":"School of Mathematics and System Science, Shenyang Normal University, Shenyang, 110034, China. fuch@synu.edu.cn","institution_ids":["https://openalex.org/I32399674"]},{"raw_affiliation_string":"School of Mathematics and Computational Science, Xiangtan University, Xiangtan, 411105, China","institution_ids":["https://openalex.org/I4610292"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062270496","display_name":"Su Deng","orcid":"https://orcid.org/0000-0002-0835-2452"},"institutions":[{"id":"https://openalex.org/I32399674","display_name":"Shenyang Normal University","ror":"https://ror.org/05cdfgm80","country_code":"CN","type":"education","lineage":["https://openalex.org/I32399674"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Su Deng","raw_affiliation_strings":["School of Mathematics and System Science, Shenyang Normal University, Shenyang, 110034, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Mathematics and System Science, Shenyang Normal University, Shenyang, 110034, China","institution_ids":["https://openalex.org/I32399674"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068877110","display_name":"Guangxu Jin","orcid":"https://orcid.org/0000-0001-9451-4886"},"institutions":[{"id":"https://openalex.org/I47251452","display_name":"Wake Forest University","ror":"https://ror.org/0207ad724","country_code":"US","type":"education","lineage":["https://openalex.org/I47251452"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Guangxu Jin","raw_affiliation_strings":["Center of Systems Biology and Bioinformatics, Wake Forest School of Medicine, Winston-Salem, NC, 27157, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center of Systems Biology and Bioinformatics, Wake Forest School of Medicine, Winston-Salem, NC, 27157, USA","institution_ids":["https://openalex.org/I47251452"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100406820","display_name":"Xinxin Wang","orcid":"https://orcid.org/0000-0001-6393-2276"},"institutions":[{"id":"https://openalex.org/I32399674","display_name":"Shenyang Normal University","ror":"https://ror.org/05cdfgm80","country_code":"CN","type":"education","lineage":["https://openalex.org/I32399674"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xinxin Wang","raw_affiliation_strings":["School of Mathematics and System Science, Shenyang Normal University, Shenyang, 110034, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Mathematics and System Science, Shenyang Normal University, Shenyang, 110034, China","institution_ids":["https://openalex.org/I32399674"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5026047510","display_name":"Zu\u2010Guo Yu","orcid":"https://orcid.org/0000-0001-5913-9646"},"institutions":[{"id":"https://openalex.org/I4610292","display_name":"Xiangtan University","ror":"https://ror.org/00xsfaz62","country_code":"CN","type":"education","lineage":["https://openalex.org/I4610292"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Zu-Guo Yu","raw_affiliation_strings":["School of Mathematics and Computational Science, Xiangtan University, Xiangtan, 411105, China. yuzuguo@aliyun.com","School of Mathematics and Computational Science, Xiangtan University, Xiangtan, 411105, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Mathematics and Computational Science, Xiangtan University, Xiangtan, 411105, China. yuzuguo@aliyun.com","institution_ids":["https://openalex.org/I4610292"]},{"raw_affiliation_string":"School of Mathematics and Computational Science, Xiangtan University, Xiangtan, 411105, China","institution_ids":["https://openalex.org/I4610292"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5026047510","https://openalex.org/A5085489027"],"corresponding_institution_ids":["https://openalex.org/I32399674","https://openalex.org/I4610292"],"apc_list":null,"apc_paid":null,"fwci":1.2339,"has_fulltext":true,"cited_by_count":16,"citation_normalized_percentile":{"value":0.79300026,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":98},"biblio":{"volume":"11","issue":"S4","first_page":"81","last_page":"81"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9323999881744385,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9323999881744385,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.013799999840557575,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.010700000450015068,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.658257246017456},{"id":"https://openalex.org/keywords/interaction-network","display_name":"Interaction network","score":0.5645353198051453},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5541038513183594},{"id":"https://openalex.org/keywords/biological-pathway","display_name":"Biological pathway","score":0.46360906958580017},{"id":"https://openalex.org/keywords/dynamic-bayesian-network","display_name":"Dynamic Bayesian network","score":0.46234244108200073},{"id":"https://openalex.org/keywords/systems-biology","display_name":"Systems biology","score":0.4295300841331482},{"id":"https://openalex.org/keywords/bayesian-network","display_name":"Bayesian network","score":0.41614052653312683},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.397601455450058},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.3087735176086426},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.2303219437599182},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.1984831988811493}],"concepts":[{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.658257246017456},{"id":"https://openalex.org/C55105296","wikidata":"https://www.wikidata.org/wiki/Q841382","display_name":"Interaction network","level":3,"score":0.5645353198051453},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5541038513183594},{"id":"https://openalex.org/C9927688","wikidata":"https://www.wikidata.org/wiki/Q4915012","display_name":"Biological pathway","level":4,"score":0.46360906958580017},{"id":"https://openalex.org/C82142266","wikidata":"https://www.wikidata.org/wiki/Q3456604","display_name":"Dynamic Bayesian network","level":3,"score":0.46234244108200073},{"id":"https://openalex.org/C152662350","wikidata":"https://www.wikidata.org/wiki/Q815297","display_name":"Systems biology","level":2,"score":0.4295300841331482},{"id":"https://openalex.org/C33724603","wikidata":"https://www.wikidata.org/wiki/Q812540","display_name":"Bayesian network","level":2,"score":0.41614052653312683},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.397601455450058},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.3087735176086426},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2303219437599182},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.1984831988811493},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D001499","descriptor_name":"Bayes Theorem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001499","descriptor_name":"Bayes Theorem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001499","descriptor_name":"Bayes Theorem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D025941","descriptor_name":"Protein Interaction Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D025941","descriptor_name":"Protein Interaction Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D025941","descriptor_name":"Protein Interaction Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D053263","descriptor_name":"Gene Regulatory Networks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D053263","descriptor_name":"Gene Regulatory Networks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D053263","descriptor_name":"Gene Regulatory Networks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1186/s12918-017-0454-9","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12918-017-0454-9","pdf_url":"https://bmcsystbiol.biomedcentral.com/track/pdf/10.1186/s12918-017-0454-9","source":{"id":"https://openalex.org/S92363890","display_name":"BMC Systems Biology","issn_l":"1752-0509","issn":["1752-0509"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Systems Biology","raw_type":"journal-article"},{"id":"pmid:28950903","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28950903","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC systems biology","raw_type":null},{"id":"pmh:oai:doaj.org/article:af74b065f54f4c588b1eea52450da3f3","is_oa":false,"landing_page_url":"https://doaj.org/article/af74b065f54f4c588b1eea52450da3f3","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Systems Biology, Vol 11, Iss S4, Pp 35-42 (2017)","raw_type":"article"},{"id":"pmh:oai:europepmc.org:4538929","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5615243","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/s12918-017-0454-9","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12918-017-0454-9","pdf_url":"https://bmcsystbiol.biomedcentral.com/track/pdf/10.1186/s12918-017-0454-9","source":{"id":"https://openalex.org/S92363890","display_name":"BMC Systems Biology","issn_l":"1752-0509","issn":["1752-0509"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Systems Biology","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1562184459","display_name":"\u5206\u5f62\u53ca\u76f8\u5173\u65b9\u6cd5\u5728\u5206\u5b50\u8fdb\u5316\u4e0e\u86cb\u767d\u8d28\u7814\u7a76\u4e2d\u7684\u5e94\u7528","funder_award_id":"11371016","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320338204","display_name":"Program for Changjiang Scholars and Innovative Research Team in University","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2757839622.pdf","grobid_xml":"https://content.openalex.org/works/W2757839622.grobid-xml"},"referenced_works_count":32,"referenced_works":["https://openalex.org/W1513873506","https://openalex.org/W1529730227","https://openalex.org/W1964115714","https://openalex.org/W1976937534","https://openalex.org/W1977071397","https://openalex.org/W1993628165","https://openalex.org/W2003652380","https://openalex.org/W2010134474","https://openalex.org/W2013520054","https://openalex.org/W2042688172","https://openalex.org/W2054954256","https://openalex.org/W2073060623","https://openalex.org/W2073881372","https://openalex.org/W2084377907","https://openalex.org/W2085060592","https://openalex.org/W2098834804","https://openalex.org/W2104009289","https://openalex.org/W2110095004","https://openalex.org/W2117033519","https://openalex.org/W2124288003","https://openalex.org/W2129997546","https://openalex.org/W2130139983","https://openalex.org/W2131532450","https://openalex.org/W2133102806","https://openalex.org/W2133992568","https://openalex.org/W2137804845","https://openalex.org/W2159080219","https://openalex.org/W2159460045","https://openalex.org/W2163296115","https://openalex.org/W2167190345","https://openalex.org/W2318485605","https://openalex.org/W3099289621"],"related_works":["https://openalex.org/W2578973671","https://openalex.org/W2215058820","https://openalex.org/W2945000716","https://openalex.org/W2097663773","https://openalex.org/W1602184117","https://openalex.org/W2511198839","https://openalex.org/W1966557338","https://openalex.org/W2366931106","https://openalex.org/W2105734437","https://openalex.org/W1760163131"],"abstract_inverted_index":{"BACKGROUND:":[0],"Molecular":[1],"interaction":[2,36,74,90,93,124,137,206,218,259],"data":[3,54,94,129,138,260],"at":[4,261],"proteomic":[5,56,262],"and":[6,11,18,57,91,95,109,126,168,176,263],"genetic":[7,35,58,89,123,217,264],"levels":[8],"provide":[9],"physical":[10],"functional":[12],"insights":[13],"into":[14],"a":[15,84,210,246],"molecular":[16],"biosystem":[17],"are":[19,200],"helpful":[20],"for":[21,116],"the":[22,53,103,117,121,127,142,222,226,229,234,270],"construction":[23],"of":[24,73,120,131,236],"pathway":[25,48,69,99,104,152,175,178,256],"structures":[26,257],"complementarily.":[27],"Despite":[28],"advances":[29],"in":[30,42,225,275],"inferring":[31],"biological":[32],"pathways":[33,115,278],"using":[34],"data,":[37],"there":[38],"still":[39],"exists":[40],"weakness":[41,197],"developed":[43,245,271],"models,":[44],"such":[45],"as,":[46],"activity":[47],"networks":[49],"(APN),":[50],"when":[51],"integrating":[52],"from":[55,141,180,185,258],"levels.":[59,265],"It":[60],"is":[61,192,240],"necessary":[62],"to":[63,67,82,113,194,203,220,253],"develop":[64,83],"new":[65,85,247],"methods":[66],"infer":[68,114,254],"structure":[70],"by":[71],"both":[72],"data.":[75],"RESULTS:":[76],"We":[77,101,244],"utilized":[78],"probabilistic":[79],"graphical":[80],"model":[81,112],"method":[86,146,191,239,248,272],"that":[87,184,189,214,269],"integrates":[88],"protein":[92,136,205],"infers":[96],"exquisitely":[97],"detailed":[98,255],"structure.":[100],"modeled":[102],"network":[105,108,252],"as":[106],"Bayesian":[107,251],"applied":[110],"this":[111],"coherent":[118],"subsets":[119],"global":[122],"profiles,":[125],"available":[128],"set":[130],"endoplasmic":[132],"reticulum":[133],"genes.":[134],"The":[135,266],"were":[139],"derived":[140],"BioGRID":[143],"database.":[144],"Our":[145],"can":[147],"accurately":[148],"reconstruct":[149],"known":[150],"cellular":[151],"structures,":[153],"including":[154],"SWR":[155],"complex,":[156,165,167],"ER-Associated":[157],"Degradation":[158],"(ERAD)":[159],"pathway,":[160,163],"N-Glycan":[161,173],"biosynthesis":[162,174],"Elongator":[164],"Retromer":[166],"Urmylation":[169,177],"pathway.":[170],"By":[171],"comparing":[172],"identified":[179],"our":[181,190,237],"approach":[182],"with":[183],"APN,":[186],"we":[187,208],"found":[188],"able":[193],"overcome":[195],"its":[196],"(certain":[198],"edges":[199],"inexplicable).":[201],"According":[202],"underlying":[204],"network,":[207],"defined":[209],"simple":[211],"scoring":[212],"function":[213],"only":[215],"adopts":[216],"information":[219],"avoid":[221],"balance":[223],"difficulty":[224],"APN.":[227],"Using":[228],"effective":[230],"stochastic":[231],"simulation":[232],"algorithm,":[233],"performance":[235],"proposed":[238],"significantly":[241],"high.":[242],"CONCLUSION:":[243],"based":[249],"on":[250],"results":[267],"indicate":[268],"performs":[273],"better":[274],"predicting":[276],"signaling":[277],"than":[279],"previously":[280],"described":[281],"models.":[282]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":3}],"updated_date":"2026-06-19T15:47:20.252518","created_date":"2025-10-10T00:00:00"}