{"id":"https://openalex.org/W2613610851","doi":"https://doi.org/10.1186/s12918-017-0443-z","title":"Modeling de novo granulation of anaerobic sludge","display_name":"Modeling de novo granulation of anaerobic sludge","publication_year":2017,"publication_date":"2017-07-17","ids":{"openalex":"https://openalex.org/W2613610851","doi":"https://doi.org/10.1186/s12918-017-0443-z","mag":"2613610851","pmid":"https://pubmed.ncbi.nlm.nih.gov/28716030"},"language":"en","primary_location":{"id":"doi:10.1186/s12918-017-0443-z","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12918-017-0443-z","pdf_url":null,"source":{"id":"https://openalex.org/S92363890","display_name":"BMC Systems Biology","issn_l":"1752-0509","issn":["1752-0509"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Systems Biology","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://doi.org/10.1186/s12918-017-0443-z","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5061545974","display_name":"Anna Doloman","orcid":"https://orcid.org/0000-0001-6899-277X"},"institutions":[{"id":"https://openalex.org/I121980950","display_name":"Utah State University","ror":"https://ror.org/00h6set76","country_code":"US","type":"education","lineage":["https://openalex.org/I121980950"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Anna Doloman","raw_affiliation_strings":["Department of Biological Engineering, Utah State University, Old Main Hill 4105, Logan, 84322-4105, UT, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Engineering, Utah State University, Old Main Hill 4105, Logan, 84322-4105, UT, USA","institution_ids":["https://openalex.org/I121980950"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017995685","display_name":"Honey Varghese","orcid":null},"institutions":[{"id":"https://openalex.org/I121980950","display_name":"Utah State University","ror":"https://ror.org/00h6set76","country_code":"US","type":"education","lineage":["https://openalex.org/I121980950"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Honey Varghese","raw_affiliation_strings":["Department of Computer Science, Utah State University, Old Main Hill 420, Logan, 84322-4205, UT, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science, Utah State University, Old Main Hill 420, Logan, 84322-4205, UT, USA","institution_ids":["https://openalex.org/I121980950"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031442944","display_name":"Charles Miller","orcid":"https://orcid.org/0000-0002-3202-6323"},"institutions":[{"id":"https://openalex.org/I121980950","display_name":"Utah State University","ror":"https://ror.org/00h6set76","country_code":"US","type":"education","lineage":["https://openalex.org/I121980950"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Charles D. Miller","raw_affiliation_strings":["Department of Biological Engineering, Utah State University, Old Main Hill 4105, Logan, 84322-4105, UT, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Engineering, Utah State University, Old Main Hill 4105, Logan, 84322-4105, UT, USA","institution_ids":["https://openalex.org/I121980950"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5033749663","display_name":"Nicholas S. Flann","orcid":"https://orcid.org/0000-0002-3100-8545"},"institutions":[{"id":"https://openalex.org/I121980950","display_name":"Utah State University","ror":"https://ror.org/00h6set76","country_code":"US","type":"education","lineage":["https://openalex.org/I121980950"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nicholas S. Flann","raw_affiliation_strings":["Department of Computer Science, Utah State University, Old Main Hill 420, Logan, 84322-4205, UT, USA. nick.flann@usu.edu","Department of Computer Science, Utah State University, Old Main Hill 420, Logan, 84322-4205, UT, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science, Utah State University, Old Main Hill 420, Logan, 84322-4205, UT, USA. nick.flann@usu.edu","institution_ids":[]},{"raw_affiliation_string":"Department of Computer Science, Utah State University, Old Main Hill 420, Logan, 84322-4205, UT, USA","institution_ids":["https://openalex.org/I121980950"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5061545974"],"corresponding_institution_ids":["https://openalex.org/I121980950"],"apc_list":null,"apc_paid":null,"fwci":2.3572,"has_fulltext":true,"cited_by_count":27,"citation_normalized_percentile":{"value":0.87671602,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":98},"biblio":{"volume":"11","issue":"1","first_page":"69","last_page":"69"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10284","display_name":"Anaerobic Digestion and Biogas Production","score":0.9502000212669373,"subfield":{"id":"https://openalex.org/subfields/2215","display_name":"Building and Construction"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10284","display_name":"Anaerobic Digestion and Biogas Production","score":0.9502000212669373,"subfield":{"id":"https://openalex.org/subfields/2215","display_name":"Building and Construction"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11952","display_name":"Landfill Environmental Impact Studies","score":0.020600000396370888,"subfield":{"id":"https://openalex.org/subfields/2311","display_name":"Industrial and Manufacturing Engineering"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10564","display_name":"Wastewater Treatment and Nitrogen Removal","score":0.014299999922513962,"subfield":{"id":"https://openalex.org/subfields/2310","display_name":"Pollution"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/granulation","display_name":"Granulation","score":0.9139971137046814},{"id":"https://openalex.org/keywords/granule","display_name":"Granule (geology)","score":0.7951908111572266},{"id":"https://openalex.org/keywords/anaerobic-exercise","display_name":"Anaerobic exercise","score":0.6337671279907227},{"id":"https://openalex.org/keywords/anaerobic-digestion","display_name":"Anaerobic digestion","score":0.575379490852356},{"id":"https://openalex.org/keywords/multicellular-organism","display_name":"Multicellular organism","score":0.5038937926292419},{"id":"https://openalex.org/keywords/bioreactor","display_name":"Bioreactor","score":0.4932534098625183},{"id":"https://openalex.org/keywords/biochemical-engineering","display_name":"Biochemical engineering","score":0.44475504755973816},{"id":"https://openalex.org/keywords/population","display_name":"Population","score":0.4290695786476135},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.41478216648101807},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.368137001991272},{"id":"https://openalex.org/keywords/biological-system","display_name":"Biological system","score":0.3349972367286682},{"id":"https://openalex.org/keywords/methane","display_name":"Methane","score":0.29739898443222046},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.19578036665916443},{"id":"https://openalex.org/keywords/cell","display_name":"Cell","score":0.164201557636261},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.16309210658073425},{"id":"https://openalex.org/keywords/ecology","display_name":"Ecology","score":0.14133021235466003},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.1078401505947113},{"id":"https://openalex.org/keywords/physiology","display_name":"Physiology","score":0.06893625855445862}],"concepts":[{"id":"https://openalex.org/C88463166","wikidata":"https://www.wikidata.org/wiki/Q1543243","display_name":"Granulation","level":2,"score":0.9139971137046814},{"id":"https://openalex.org/C49760210","wikidata":"https://www.wikidata.org/wiki/Q5596727","display_name":"Granule (geology)","level":2,"score":0.7951908111572266},{"id":"https://openalex.org/C5140985","wikidata":"https://www.wikidata.org/wiki/Q483866","display_name":"Anaerobic exercise","level":2,"score":0.6337671279907227},{"id":"https://openalex.org/C499616599","wikidata":"https://www.wikidata.org/wiki/Q555853","display_name":"Anaerobic digestion","level":3,"score":0.575379490852356},{"id":"https://openalex.org/C74318829","wikidata":"https://www.wikidata.org/wiki/Q36458","display_name":"Multicellular organism","level":3,"score":0.5038937926292419},{"id":"https://openalex.org/C168170006","wikidata":"https://www.wikidata.org/wiki/Q864699","display_name":"Bioreactor","level":2,"score":0.4932534098625183},{"id":"https://openalex.org/C183696295","wikidata":"https://www.wikidata.org/wiki/Q2487696","display_name":"Biochemical engineering","level":1,"score":0.44475504755973816},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.4290695786476135},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.41478216648101807},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.368137001991272},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.3349972367286682},{"id":"https://openalex.org/C516920438","wikidata":"https://www.wikidata.org/wiki/Q37129","display_name":"Methane","level":2,"score":0.29739898443222046},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.19578036665916443},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.164201557636261},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.16309210658073425},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.14133021235466003},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.1078401505947113},{"id":"https://openalex.org/C42407357","wikidata":"https://www.wikidata.org/wiki/Q521","display_name":"Physiology","level":1,"score":0.06893625855445862},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.0},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.0},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000693","descriptor_name":"Anaerobiosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000693","descriptor_name":"Anaerobiosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000693","descriptor_name":"Anaerobiosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001696","descriptor_name":"Biomechanical Phenomena","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001696","descriptor_name":"Biomechanical Phenomena","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001696","descriptor_name":"Biomechanical Phenomena","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012722","descriptor_name":"Sewage","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D012722","descriptor_name":"Sewage","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D012722","descriptor_name":"Sewage","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D019149","descriptor_name":"Bioreactors","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D019149","descriptor_name":"Bioreactors","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D019149","descriptor_name":"Bioreactors","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D049490","descriptor_name":"Systems Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049490","descriptor_name":"Systems Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049490","descriptor_name":"Systems Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1186/s12918-017-0443-z","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12918-017-0443-z","pdf_url":null,"source":{"id":"https://openalex.org/S92363890","display_name":"BMC Systems Biology","issn_l":"1752-0509","issn":["1752-0509"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Systems Biology","raw_type":"journal-article"},{"id":"pmid:28716030","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28716030","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC systems biology","raw_type":null},{"id":"pmh:oai:digitalcommons.usu.edu:computer_science_facpubs-1004","is_oa":true,"landing_page_url":"https://digitalcommons.usu.edu/computer_science_facpubs/5","pdf_url":"https://digitalcommons.usu.edu/cgi/viewcontent.cgi?article=1004&context=computer_science_facpubs","source":{"id":"https://openalex.org/S4377196327","display_name":"Digital Commons - USU (Utah State University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I121980950","host_organization_name":"Utah State University","host_organization_lineage":["https://openalex.org/I121980950"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Computer Science Faculty and Staff Publications","raw_type":"text"},{"id":"pmh:oai:doaj.org/article:8c22286b4e9d4c3f8889293b22acbf9d","is_oa":false,"landing_page_url":"https://doaj.org/article/8c22286b4e9d4c3f8889293b22acbf9d","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Systems Biology, Vol 11, Iss 1, Pp 1-12 (2017)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:5514506","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5514506","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Syst Biol","raw_type":"Text"},{"id":"pmh:wur:oai:library.wur.nl:wurpubs/610260","is_oa":true,"landing_page_url":"https://research.wur.nl/en/publications/modeling-de-novo-granulation-of-anaerobic-sludge","pdf_url":null,"source":{"id":"https://openalex.org/S4306401843","display_name":"Data Archiving and Networked Services (DANS)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1322597698","host_organization_name":"Royal Netherlands Academy of Arts and Sciences","host_organization_lineage":["https://openalex.org/I1322597698"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Systems Biology, 11(1)","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1186/s12918-017-0443-z","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12918-017-0443-z","pdf_url":null,"source":{"id":"https://openalex.org/S92363890","display_name":"BMC Systems Biology","issn_l":"1752-0509","issn":["1752-0509"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Systems Biology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Clean water and sanitation","id":"https://metadata.un.org/sdg/6","score":0.8700000047683716}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":65,"referenced_works":["https://openalex.org/W79862949","https://openalex.org/W80264171","https://openalex.org/W1501631531","https://openalex.org/W1525693196","https://openalex.org/W1552467429","https://openalex.org/W1579234684","https://openalex.org/W1594361632","https://openalex.org/W1628968506","https://openalex.org/W1819951161","https://openalex.org/W1856772967","https://openalex.org/W1894802175","https://openalex.org/W1982987489","https://openalex.org/W1984595647","https://openalex.org/W1986298482","https://openalex.org/W1987162245","https://openalex.org/W1989006767","https://openalex.org/W1998859851","https://openalex.org/W2002785668","https://openalex.org/W2007353506","https://openalex.org/W2011129325","https://openalex.org/W2012111519","https://openalex.org/W2014023425","https://openalex.org/W2014047975","https://openalex.org/W2017054362","https://openalex.org/W2018556196","https://openalex.org/W2019347117","https://openalex.org/W2025393244","https://openalex.org/W2027574463","https://openalex.org/W2030481147","https://openalex.org/W2040759815","https://openalex.org/W2044038417","https://openalex.org/W2047722687","https://openalex.org/W2049127391","https://openalex.org/W2049514755","https://openalex.org/W2052201272","https://openalex.org/W2080317669","https://openalex.org/W2108977514","https://openalex.org/W2110626970","https://openalex.org/W2115957908","https://openalex.org/W2117899937","https://openalex.org/W2128906145","https://openalex.org/W2129733219","https://openalex.org/W2132905138","https://openalex.org/W2138908006","https://openalex.org/W2139816774","https://openalex.org/W2149861854","https://openalex.org/W2150582393","https://openalex.org/W2151291599","https://openalex.org/W2153223562","https://openalex.org/W2154156116","https://openalex.org/W2155123192","https://openalex.org/W2156597459","https://openalex.org/W2160135160","https://openalex.org/W2169931352","https://openalex.org/W2299764375","https://openalex.org/W2341072424","https://openalex.org/W2511630048","https://openalex.org/W2517300721","https://openalex.org/W2530996262","https://openalex.org/W2531008133","https://openalex.org/W2613861766","https://openalex.org/W2803607784","https://openalex.org/W2804589108","https://openalex.org/W4243044797","https://openalex.org/W6646853641"],"related_works":["https://openalex.org/W2900871462","https://openalex.org/W2272229362","https://openalex.org/W1589095441","https://openalex.org/W2971065325","https://openalex.org/W1963752889","https://openalex.org/W2313388311","https://openalex.org/W4365511630","https://openalex.org/W2177924839","https://openalex.org/W1966512669","https://openalex.org/W2068425400"],"abstract_inverted_index":{"A":[0],"unique":[1],"combination":[2],"of":[3,13,42,67,99,108,123,139,149,171,174,181,191,203,211,218,229,241],"mechanical,":[4],"physiochemical":[5,54],"and":[6,40,55,61,106,183,187,213],"biological":[7,56],"forces":[8],"influences":[9],"granulation":[10,60,87,141,195],"during":[11],"processes":[12,57],"anaerobic":[14,68,147,175,192,205,244],"digestion.":[15],"Understanding":[16],"this":[17,46],"process":[18],"requires":[19],"a":[20,63,78,84,89,109,126,208,226,230],"systems":[21,231,237],"biology":[22,232],"approach":[23,233],"due":[24],"to":[25,28,199,214,234],"the":[26,37,43,51,94,140,146,154,167,169,201,204,219,239],"need":[27],"consider":[29],"not":[30],"just":[31],"single-cell":[32],"metabolic":[33],"processes,":[34],"but":[35],"also":[36],"multicellular":[38,172,236],"organization":[39,173],"development":[41],"granule.":[44],"In":[45,166],"computational":[47],"experiment,":[48],"we":[49],"address":[50],"role":[52],"that":[53],"play":[58],"in":[59,77,88,114,135,156,207],"provide":[62],"literature-validated":[64],"working":[65],"model":[66,75,142,190,235],"granule":[69,113],"de":[70,85,193],"novo":[71,86,194],"formation.":[72],"The":[73,117,189,223],"agent-based":[74],"developed":[76],"cDynoMiCs":[79],"simulation":[80],"environment":[81],"successfully":[82],"demonstrated":[83],"glucose":[90],"fed":[91],"system,":[92],"with":[93,238],"average":[95],"specific":[96],"methanogenic":[97],"activity":[98],"1.11":[100],"ml":[101],"C":[102],"H":[103],"4/g":[104],"biomass":[105],"formation":[107],"0.5":[110],"mm":[111],"mature":[112],"33":[115],"days.":[116],"simulated":[118],"granules":[119,176,206],"exhibit":[120],"experimental":[121,160],"observations":[122],"radial":[124],"stratification:":[125],"central":[127],"dead":[128],"core":[129],"surrounded":[130],"by":[131,152],"methanogens":[132,182],"then":[133],"encased":[134],"acidogens.":[136],"Practical":[137],"application":[138],"was":[143,185],"assessed":[144],"on":[145],"digestion":[148,245],"low-strength":[150],"wastewater":[151],"measuring":[153],"changes":[155],"methane":[157,216],"yield":[158],"as":[159],"configuration":[161],"parameters":[162],"were":[163],"systematically":[164],"searched.":[165],"model,":[168],"emergence":[170],"from":[177],"randomly":[178],"mixed":[179],"population":[180],"acidogens":[184],"observed":[186],"validated.":[188],"can":[196],"be":[197],"used":[198],"predict":[200],"morphology":[202],"alternative":[209],"substrates":[210],"interest":[212],"estimate":[215],"potential":[217],"resulting":[220],"microbial":[221],"consortia.":[222],"study":[224],"demonstrates":[225],"successful":[227],"integration":[228],"engineering":[240],"an":[242],"efficient":[243],"system.":[246]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":1}],"updated_date":"2026-05-16T08:24:45.110214","created_date":"2025-10-10T00:00:00"}