{"id":"https://openalex.org/W2019062641","doi":"https://doi.org/10.1186/s12918-015-0145-3","title":"microRNAs\u2019 differential regulations mediate the progress of Human Papillomavirus (HPV)-induced Cervical Intraepithelial Neoplasia (CIN)","display_name":"microRNAs\u2019 differential regulations mediate the progress of Human Papillomavirus (HPV)-induced Cervical Intraepithelial Neoplasia (CIN)","publication_year":2015,"publication_date":"2015-02-06","ids":{"openalex":"https://openalex.org/W2019062641","doi":"https://doi.org/10.1186/s12918-015-0145-3","mag":"2019062641","pmid":"https://pubmed.ncbi.nlm.nih.gov/25889737"},"language":"en","primary_location":{"id":"doi:10.1186/s12918-015-0145-3","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12918-015-0145-3","pdf_url":"https://bmcsystbiol.biomedcentral.com/counter/pdf/10.1186/s12918-015-0145-3","source":{"id":"https://openalex.org/S92363890","display_name":"BMC Systems Biology","issn_l":"1752-0509","issn":["1752-0509"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Systems Biology","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://bmcsystbiol.biomedcentral.com/counter/pdf/10.1186/s12918-015-0145-3","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5070955252","display_name":"Wenjuan Mo","orcid":"https://orcid.org/0009-0003-6124-7955"},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wenjuan Mo","raw_affiliation_strings":["Collaborative Innovation Center of Cancer Medicine, 200433, Shanghai, China. wenjuanmo@fudan.edu.cn","Shanghai Engineering Research Center of Industrial Microorganisms, 200433, Shanghai, China. wenjuanmo@fudan.edu.cn","State Key Laboratory of Genetic Engineering, School of Life Science, and Institute of Biomedical Sciences, Fudan University, 200433, Shanghai, China. wenjuanmo@fudan.edu.cn","State Key Laboratory of Genetic Engineering, School of Life Science, and Institute of Biomedical Sciences, Fudan University, 200433, Shanghai, China"],"affiliations":[{"raw_affiliation_string":"Collaborative Innovation Center of Cancer Medicine, 200433, Shanghai, China. wenjuanmo@fudan.edu.cn","institution_ids":[]},{"raw_affiliation_string":"Shanghai Engineering Research Center of Industrial Microorganisms, 200433, Shanghai, China. wenjuanmo@fudan.edu.cn","institution_ids":[]},{"raw_affiliation_string":"State Key Laboratory of Genetic Engineering, School of Life Science, and Institute of Biomedical Sciences, Fudan University, 200433, Shanghai, China. wenjuanmo@fudan.edu.cn","institution_ids":[]},{"raw_affiliation_string":"State Key Laboratory of Genetic Engineering, School of Life Science, and Institute of Biomedical Sciences, Fudan University, 200433, Shanghai, China","institution_ids":["https://openalex.org/I24943067"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060491389","display_name":"Chao Tong","orcid":"https://orcid.org/0000-0003-0828-2674"},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chao Tong","raw_affiliation_strings":["Collaborative Innovation Center of Cancer Medicine, 200433, Shanghai, China. chaotong@fudan.edu.cn","Shanghai Engineering Research Center of Industrial Microorganisms, 200433, Shanghai, China. chaotong@fudan.edu.cn","State Key Laboratory of Genetic Engineering, School of Life Science, and Institute of Biomedical Sciences, Fudan University, 200433, Shanghai, China. chaotong@fudan.edu.cn","State Key Laboratory of Genetic Engineering, School of Life Science, and Institute of Biomedical Sciences, Fudan University, 200433, Shanghai, China"],"affiliations":[{"raw_affiliation_string":"Collaborative Innovation Center of Cancer Medicine, 200433, Shanghai, China. chaotong@fudan.edu.cn","institution_ids":[]},{"raw_affiliation_string":"Shanghai Engineering Research Center of Industrial Microorganisms, 200433, Shanghai, China. chaotong@fudan.edu.cn","institution_ids":[]},{"raw_affiliation_string":"State Key Laboratory of Genetic Engineering, School of Life Science, and Institute of Biomedical Sciences, Fudan University, 200433, Shanghai, China. chaotong@fudan.edu.cn","institution_ids":[]},{"raw_affiliation_string":"State Key Laboratory of Genetic Engineering, School of Life Science, and Institute of Biomedical Sciences, Fudan University, 200433, Shanghai, China","institution_ids":["https://openalex.org/I24943067"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100456117","display_name":"Yan Zhang","orcid":"https://orcid.org/0000-0001-6213-4416"},"institutions":[{"id":"https://openalex.org/I4210115928","display_name":"Changhai Hospital","ror":"https://ror.org/02bjs0p66","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210115928"]},{"id":"https://openalex.org/I177933477","display_name":"Second Military Medical University","ror":"https://ror.org/04tavpn47","country_code":"CN","type":"education","lineage":["https://openalex.org/I177933477"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Yan Zhang","raw_affiliation_strings":["Department of Gynaecology and Obstetrics in Changhai Hospital, 200433, Shanghai, China. zhangyan186168@163.com","Department of Gynaecology and Obstetrics in Changhai Hospital, 200433, Shanghai, China"],"affiliations":[{"raw_affiliation_string":"Department of Gynaecology and Obstetrics in Changhai Hospital, 200433, Shanghai, China. zhangyan186168@163.com","institution_ids":[]},{"raw_affiliation_string":"Department of Gynaecology and Obstetrics in Changhai Hospital, 200433, Shanghai, China","institution_ids":["https://openalex.org/I4210115928","https://openalex.org/I177933477"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5082084368","display_name":"Hong L\u00fc","orcid":"https://orcid.org/0000-0003-3449-8153"},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hong Lu","raw_affiliation_strings":["Collaborative Innovation Center of Cancer Medicine, 200433, Shanghai, China. honglu0211@yahoo.com","Shanghai Engineering Research Center of Industrial Microorganisms, 200433, Shanghai, China. honglu0211@yahoo.com","State Key Laboratory of Genetic Engineering, School of Life Science, and Institute of Biomedical Sciences, Fudan University, 200433, Shanghai, China. honglu0211@yahoo.com","State Key Laboratory of Genetic Engineering, School of Life Science, and Institute of Biomedical Sciences, Fudan University, 200433, Shanghai, China"],"affiliations":[{"raw_affiliation_string":"Collaborative Innovation Center of Cancer Medicine, 200433, Shanghai, China. honglu0211@yahoo.com","institution_ids":[]},{"raw_affiliation_string":"Shanghai Engineering Research Center of Industrial Microorganisms, 200433, Shanghai, China. honglu0211@yahoo.com","institution_ids":[]},{"raw_affiliation_string":"State Key Laboratory of Genetic Engineering, School of Life Science, and Institute of Biomedical Sciences, Fudan University, 200433, Shanghai, China. honglu0211@yahoo.com","institution_ids":[]},{"raw_affiliation_string":"State Key Laboratory of Genetic Engineering, School of Life Science, and Institute of Biomedical Sciences, Fudan University, 200433, Shanghai, China","institution_ids":["https://openalex.org/I24943067"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5100456117"],"corresponding_institution_ids":["https://openalex.org/I177933477","https://openalex.org/I4210115928"],"apc_list":null,"apc_paid":null,"fwci":1.8748,"has_fulltext":true,"cited_by_count":26,"citation_normalized_percentile":{"value":0.84274129,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"9","issue":"1","first_page":"4","last_page":"4"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.9991999864578247,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.9991999864578247,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":0.9991999864578247,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11765","display_name":"Circular RNAs in diseases","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/microrna","display_name":"microRNA","score":0.8422152996063232},{"id":"https://openalex.org/keywords/cervical-intraepithelial-neoplasia","display_name":"Cervical intraepithelial neoplasia","score":0.7726807594299316},{"id":"https://openalex.org/keywords/carcinogenesis","display_name":"Carcinogenesis","score":0.6418238878250122},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.5950093269348145},{"id":"https://openalex.org/keywords/cervical-cancer","display_name":"Cervical cancer","score":0.5761677622795105},{"id":"https://openalex.org/keywords/gene-silencing","display_name":"Gene silencing","score":0.5053334832191467},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.4893135726451874},{"id":"https://openalex.org/keywords/disease","display_name":"Disease","score":0.45754075050354004},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.36391153931617737},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.337592214345932},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.2260403335094452},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.2094114124774933},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.2064794898033142},{"id":"https://openalex.org/keywords/pathology","display_name":"Pathology","score":0.13573384284973145}],"concepts":[{"id":"https://openalex.org/C145059251","wikidata":"https://www.wikidata.org/wiki/Q310899","display_name":"microRNA","level":3,"score":0.8422152996063232},{"id":"https://openalex.org/C2777343196","wikidata":"https://www.wikidata.org/wiki/Q196788","display_name":"Cervical intraepithelial neoplasia","level":4,"score":0.7726807594299316},{"id":"https://openalex.org/C555283112","wikidata":"https://www.wikidata.org/wiki/Q1637543","display_name":"Carcinogenesis","level":3,"score":0.6418238878250122},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5950093269348145},{"id":"https://openalex.org/C2778220009","wikidata":"https://www.wikidata.org/wiki/Q160105","display_name":"Cervical cancer","level":3,"score":0.5761677622795105},{"id":"https://openalex.org/C119056186","wikidata":"https://www.wikidata.org/wiki/Q1431332","display_name":"Gene silencing","level":3,"score":0.5053334832191467},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4893135726451874},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.45754075050354004},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.36391153931617737},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.337592214345932},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2260403335094452},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2094114124774933},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2064794898033142},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.13573384284973145}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002578","descriptor_name":"Uterine Cervical Dysplasia","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002578","descriptor_name":"Uterine Cervical Dysplasia","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002578","descriptor_name":"Uterine Cervical Dysplasia","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002578","descriptor_name":"Uterine Cervical Dysplasia","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D002578","descriptor_name":"Uterine Cervical Dysplasia","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D002578","descriptor_name":"Uterine Cervical Dysplasia","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D002578","descriptor_name":"Uterine Cervical Dysplasia","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D002578","descriptor_name":"Uterine Cervical Dysplasia","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D002578","descriptor_name":"Uterine Cervical Dysplasia","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D002583","descriptor_name":"Uterine Cervical Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002583","descriptor_name":"Uterine Cervical Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002583","descriptor_name":"Uterine Cervical Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002583","descriptor_name":"Uterine Cervical Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D002583","descriptor_name":"Uterine Cervical Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D002583","descriptor_name":"Uterine Cervical Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D002583","descriptor_name":"Uterine Cervical Neoplasms","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D002583","descriptor_name":"Uterine Cervical Neoplasms","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D002583","descriptor_name":"Uterine Cervical Neoplasms","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D027383","descriptor_name":"Papillomaviridae","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D027383","descriptor_name":"Papillomaviridae","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D027383","descriptor_name":"Papillomaviridae","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D053263","descriptor_name":"Gene Regulatory Networks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053263","descriptor_name":"Gene Regulatory Networks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053263","descriptor_name":"Gene Regulatory Networks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D063646","descriptor_name":"Carcinogenesis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D063646","descriptor_name":"Carcinogenesis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D063646","descriptor_name":"Carcinogenesis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1186/s12918-015-0145-3","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12918-015-0145-3","pdf_url":"https://bmcsystbiol.biomedcentral.com/counter/pdf/10.1186/s12918-015-0145-3","source":{"id":"https://openalex.org/S92363890","display_name":"BMC Systems Biology","issn_l":"1752-0509","issn":["1752-0509"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Systems Biology","raw_type":"journal-article"},{"id":"pmid:25889737","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25889737","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC systems biology","raw_type":null},{"id":"pmh:oai:europepmc.org:3301457","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4337110","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/s12918-015-0145-3","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12918-015-0145-3","pdf_url":"https://bmcsystbiol.biomedcentral.com/counter/pdf/10.1186/s12918-015-0145-3","source":{"id":"https://openalex.org/S92363890","display_name":"BMC Systems Biology","issn_l":"1752-0509","issn":["1752-0509"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Systems Biology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.6700000166893005,"display_name":"Good health and well-being"}],"awards":[{"id":"https://openalex.org/G1121271761","display_name":null,"funder_award_id":"Program","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G1231421488","display_name":null,"funder_award_id":"under","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G1828425977","display_name":null,"funder_award_id":"973 Program","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G2082826544","display_name":null,"funder_award_id":"Postdoctoral","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G2087396116","display_name":null,"funder_award_id":"China","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G2869252913","display_name":null,"funder_award_id":"91129730","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G3317480652","display_name":null,"funder_award_id":"Science","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G391238517","display_name":null,"funder_award_id":", and","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5848258319","display_name":null,"funder_award_id":"0 and","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5939423041","display_name":null,"funder_award_id":"Technology","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5994120800","display_name":null,"funder_award_id":"Natural","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7129907147","display_name":null,"funder_award_id":"(973 Program","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"},{"id":"https://openalex.org/G7649639274","display_name":null,"funder_award_id":"21132004","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G8863666567","display_name":null,"funder_award_id":"and No.","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320321543","display_name":"China Postdoctoral Science Foundation","ror":"https://ror.org/0426zh255"},{"id":"https://openalex.org/F4320321885","display_name":"Science and Technology Commission of Shanghai Municipality","ror":"https://ror.org/03kt66j61"},{"id":"https://openalex.org/F4320335777","display_name":"National Key Research and Development Program of China","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2019062641.pdf","grobid_xml":"https://content.openalex.org/works/W2019062641.grobid-xml"},"referenced_works_count":37,"referenced_works":["https://openalex.org/W981206040","https://openalex.org/W1975385846","https://openalex.org/W1977431865","https://openalex.org/W1982343022","https://openalex.org/W1983677002","https://openalex.org/W1984850107","https://openalex.org/W1985035024","https://openalex.org/W1986630370","https://openalex.org/W1990868443","https://openalex.org/W1992430198","https://openalex.org/W1998248450","https://openalex.org/W2002549404","https://openalex.org/W2011789480","https://openalex.org/W2013700000","https://openalex.org/W2014058353","https://openalex.org/W2020476697","https://openalex.org/W2026972134","https://openalex.org/W2028361275","https://openalex.org/W2031436446","https://openalex.org/W2035242677","https://openalex.org/W2040191060","https://openalex.org/W2043781282","https://openalex.org/W2050043492","https://openalex.org/W2053195920","https://openalex.org/W2056880902","https://openalex.org/W2063226459","https://openalex.org/W2063475378","https://openalex.org/W2071337607","https://openalex.org/W2078743501","https://openalex.org/W2094375040","https://openalex.org/W2130768936","https://openalex.org/W2133038562","https://openalex.org/W2139807849","https://openalex.org/W2139979516","https://openalex.org/W2148028028","https://openalex.org/W2166240615","https://openalex.org/W2170643981"],"related_works":["https://openalex.org/W3144241576","https://openalex.org/W2378888248","https://openalex.org/W2113725788","https://openalex.org/W2026936876","https://openalex.org/W1988174701","https://openalex.org/W2998224076","https://openalex.org/W2390801589","https://openalex.org/W2387002827","https://openalex.org/W3030112595","https://openalex.org/W2369276577"],"abstract_inverted_index":{"This":[0],"study":[1],"provided":[2],"the":[3,9,20],"conception":[4],"of":[5],"miRNA's":[6],"differential":[7,27],"regulation,":[8],"algorithm":[10],"for":[11,22,40],"how":[12,23],"to":[13,24],"identify":[14],"them":[15],"during":[16],"disease":[17],"development,":[18],"and":[19],"strategy":[21],"construct":[25],"miRNA":[26],"regulatory":[28],"network":[29],"with":[30],"instructive":[31],"biological":[32],"meanings.":[33],"The":[34],"finally":[35],"constructed":[36],"networks":[37],"provide":[38],"clues":[39],"understanding":[41],"CIN":[42],"progress.":[43]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":7},{"year":2015,"cited_by_count":1}],"updated_date":"2026-04-13T07:58:08.660418","created_date":"2025-10-10T00:00:00"}