{"id":"https://openalex.org/W2023395518","doi":"https://doi.org/10.1186/s12918-014-0085-3","title":"Ki MoSys: a web-based repository of experimental data for KInetic MOdels of biological SYStems","display_name":"Ki MoSys: a web-based repository of experimental data for KInetic MOdels of biological SYStems","publication_year":2014,"publication_date":"2014-08-12","ids":{"openalex":"https://openalex.org/W2023395518","doi":"https://doi.org/10.1186/s12918-014-0085-3","mag":"2023395518","pmid":"https://pubmed.ncbi.nlm.nih.gov/25115331"},"language":"en","primary_location":{"id":"doi:10.1186/s12918-014-0085-3","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12918-014-0085-3","pdf_url":"https://bmcsystbiol.biomedcentral.com/counter/pdf/10.1186/s12918-014-0085-3","source":{"id":"https://openalex.org/S92363890","display_name":"BMC Systems Biology","issn_l":"1752-0509","issn":["1752-0509"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Systems Biology","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://bmcsystbiol.biomedcentral.com/counter/pdf/10.1186/s12918-014-0085-3","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5026040695","display_name":"Rafael S. Costa","orcid":null},"institutions":[{"id":"https://openalex.org/I121345201","display_name":"Instituto de Engenharia de Sistemas e Computadores Investiga\u00e7\u00e3o e Desenvolvimento","ror":"https://ror.org/04mqy3p58","country_code":"PT","type":"nonprofit","lineage":["https://openalex.org/I121345201","https://openalex.org/I4210125590"]},{"id":"https://openalex.org/I141596103","display_name":"University of Lisbon","ror":"https://ror.org/01c27hj86","country_code":"PT","type":"education","lineage":["https://openalex.org/I141596103"]}],"countries":["PT"],"is_corresponding":true,"raw_author_name":"Rafael S Costa","raw_affiliation_strings":["Instituto de Engenharia de Sistemas e Computadores, Investigac\u00e3o e Desenvolvimento (INESC-ID), R Alves Redol 9, Lisboa, 1000-029, Portugal. rcosta@kdbio.inesc-id.pt","Instituto de Engenharia de Sistemas e Computadores, Investigac\u00e3o e Desenvolvimento (INESC-ID), Lisboa, Portugal","Center for Intelligent Systems, LAETA,IDMEC, Instituto Superior T\u00e9cnico, Universidade de Lisboa, Lisboa, Portugal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Instituto de Engenharia de Sistemas e Computadores, Investigac\u00e3o e Desenvolvimento (INESC-ID), R Alves Redol 9, Lisboa, 1000-029, Portugal. rcosta@kdbio.inesc-id.pt","institution_ids":[]},{"raw_affiliation_string":"Instituto de Engenharia de Sistemas e Computadores, Investigac\u00e3o e Desenvolvimento (INESC-ID), Lisboa, Portugal","institution_ids":["https://openalex.org/I121345201"]},{"raw_affiliation_string":"Center for Intelligent Systems, LAETA,IDMEC, Instituto Superior T\u00e9cnico, Universidade de Lisboa, Lisboa, Portugal","institution_ids":["https://openalex.org/I141596103"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053180327","display_name":"Andr\u00e9 Ver\u00edssimo","orcid":"https://orcid.org/0000-0002-2212-339X"},"institutions":[{"id":"https://openalex.org/I141596103","display_name":"University of Lisbon","ror":"https://ror.org/01c27hj86","country_code":"PT","type":"education","lineage":["https://openalex.org/I141596103"]},{"id":"https://openalex.org/I121345201","display_name":"Instituto de Engenharia de Sistemas e Computadores Investiga\u00e7\u00e3o e Desenvolvimento","ror":"https://ror.org/04mqy3p58","country_code":"PT","type":"nonprofit","lineage":["https://openalex.org/I121345201","https://openalex.org/I4210125590"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"Andr\u00e9 Ver\u00edssimo","raw_affiliation_strings":["Center for Intelligent Systems, LAETA,IDMEC, Instituto Superior T\u00e9cnico, Universidade de Lisboa, Av. Rovisco Pais 1, Lisboa, 1049-001, Portugal","Center for Intelligent Systems, LAETA,IDMEC, Instituto Superior T\u00e9cnico, Universidade de Lisboa, Lisboa, Portugal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Intelligent Systems, LAETA,IDMEC, Instituto Superior T\u00e9cnico, Universidade de Lisboa, Av. Rovisco Pais 1, Lisboa, 1049-001, Portugal","institution_ids":["https://openalex.org/I121345201","https://openalex.org/I141596103"]},{"raw_affiliation_string":"Center for Intelligent Systems, LAETA,IDMEC, Instituto Superior T\u00e9cnico, Universidade de Lisboa, Lisboa, Portugal","institution_ids":["https://openalex.org/I141596103"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5005271169","display_name":"Susana Vinga","orcid":"https://orcid.org/0000-0002-1954-5487"},"institutions":[{"id":"https://openalex.org/I141596103","display_name":"University of Lisbon","ror":"https://ror.org/01c27hj86","country_code":"PT","type":"education","lineage":["https://openalex.org/I141596103"]},{"id":"https://openalex.org/I121345201","display_name":"Instituto de Engenharia de Sistemas e Computadores Investiga\u00e7\u00e3o e Desenvolvimento","ror":"https://ror.org/04mqy3p58","country_code":"PT","type":"nonprofit","lineage":["https://openalex.org/I121345201","https://openalex.org/I4210125590"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"Susana Vinga","raw_affiliation_strings":["Center for Intelligent Systems, LAETA,IDMEC, Instituto Superior T\u00e9cnico, Universidade de Lisboa, Av. Rovisco Pais 1, Lisboa, 1049-001, Portugal","Center for Intelligent Systems, LAETA,IDMEC, Instituto Superior T\u00e9cnico, Universidade de Lisboa, Lisboa, Portugal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Intelligent Systems, LAETA,IDMEC, Instituto Superior T\u00e9cnico, Universidade de Lisboa, Av. Rovisco Pais 1, Lisboa, 1049-001, Portugal","institution_ids":["https://openalex.org/I121345201","https://openalex.org/I141596103"]},{"raw_affiliation_string":"Center for Intelligent Systems, LAETA,IDMEC, Instituto Superior T\u00e9cnico, Universidade de Lisboa, Lisboa, Portugal","institution_ids":["https://openalex.org/I141596103"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5026040695"],"corresponding_institution_ids":["https://openalex.org/I121345201","https://openalex.org/I141596103"],"apc_list":null,"apc_paid":null,"fwci":1.7073,"has_fulltext":true,"cited_by_count":24,"citation_normalized_percentile":{"value":0.83694341,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"8","issue":"1","first_page":"85","last_page":"85"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.9830999970436096,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.9830999970436096,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12688","display_name":"Microbial metabolism and enzyme function","score":0.0024999999441206455,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.0017999999690800905,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/upload","display_name":"Upload","score":0.755715012550354},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7001138925552368},{"id":"https://openalex.org/keywords/systems-biology","display_name":"Systems biology","score":0.5102548599243164},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.37397316098213196},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.3648250699043274},{"id":"https://openalex.org/keywords/world-wide-web","display_name":"World Wide Web","score":0.20888078212738037},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.19871044158935547},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.12496772408485413}],"concepts":[{"id":"https://openalex.org/C71901391","wikidata":"https://www.wikidata.org/wiki/Q7126699","display_name":"Upload","level":2,"score":0.755715012550354},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7001138925552368},{"id":"https://openalex.org/C152662350","wikidata":"https://www.wikidata.org/wiki/Q815297","display_name":"Systems biology","level":2,"score":0.5102548599243164},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.37397316098213196},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.3648250699043274},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.20888078212738037},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.19871044158935547},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.12496772408485413}],"mesh":[{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D049490","descriptor_name":"Systems Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D049490","descriptor_name":"Systems Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D049490","descriptor_name":"Systems Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D049490","descriptor_name":"Systems Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D053858","descriptor_name":"Metabolic Networks and Pathways","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D053858","descriptor_name":"Metabolic Networks and Pathways","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D053858","descriptor_name":"Metabolic Networks and Pathways","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D053858","descriptor_name":"Metabolic Networks and Pathways","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1186/s12918-014-0085-3","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12918-014-0085-3","pdf_url":"https://bmcsystbiol.biomedcentral.com/counter/pdf/10.1186/s12918-014-0085-3","source":{"id":"https://openalex.org/S92363890","display_name":"BMC Systems Biology","issn_l":"1752-0509","issn":["1752-0509"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Systems Biology","raw_type":"journal-article"},{"id":"pmid:25115331","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25115331","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC systems biology","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:4236735","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4236735","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Syst Biol","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/s12918-014-0085-3","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12918-014-0085-3","pdf_url":"https://bmcsystbiol.biomedcentral.com/counter/pdf/10.1186/s12918-014-0085-3","source":{"id":"https://openalex.org/S92363890","display_name":"BMC Systems Biology","issn_l":"1752-0509","issn":["1752-0509"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Systems Biology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.4699999988079071,"id":"https://metadata.un.org/sdg/17","display_name":"Partnerships for the goals"},{"score":0.4099999964237213,"id":"https://metadata.un.org/sdg/9","display_name":"Industry, innovation and infrastructure"}],"awards":[{"id":"https://openalex.org/G1355505928","display_name":null,"funder_award_id":"IF/00653/2012","funder_id":"https://openalex.org/F4320338080","funder_display_name":"European Social Fund"},{"id":"https://openalex.org/G3441820327","display_name":null,"funder_award_id":"613793","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G5209155820","display_name":null,"funder_award_id":"Pest-OE/EME/LA0022","funder_id":"https://openalex.org/F4320334779","funder_display_name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia"},{"id":"https://openalex.org/G5882453360","display_name":null,"funder_award_id":"OE/EME/LA0022","funder_id":"https://openalex.org/F4320334779","funder_display_name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia"},{"id":"https://openalex.org/G5892973716","display_name":null,"funder_award_id":"IF/00653/2012","funder_id":"https://openalex.org/F4320334779","funder_display_name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia"},{"id":"https://openalex.org/G8719395898","display_name":null,"funder_award_id":"SFRH/BPD/80784/2011","funder_id":"https://openalex.org/F4320334779","funder_display_name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia"}],"funders":[{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320334779","display_name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","ror":"https://ror.org/00snfqn58"},{"id":"https://openalex.org/F4320338080","display_name":"European Social Fund","ror":"https://ror.org/00k4n6c32"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2023395518.pdf","grobid_xml":"https://content.openalex.org/works/W2023395518.grobid-xml"},"referenced_works_count":64,"referenced_works":["https://openalex.org/W66115297","https://openalex.org/W1512810258","https://openalex.org/W1544923801","https://openalex.org/W1565036272","https://openalex.org/W1592132377","https://openalex.org/W1815377154","https://openalex.org/W1966450819","https://openalex.org/W1982258483","https://openalex.org/W1986641657","https://openalex.org/W1986703369","https://openalex.org/W1989263028","https://openalex.org/W1995238008","https://openalex.org/W1997784050","https://openalex.org/W1998034857","https://openalex.org/W2014664086","https://openalex.org/W2024858956","https://openalex.org/W2025217315","https://openalex.org/W2031739072","https://openalex.org/W2033377040","https://openalex.org/W2038282326","https://openalex.org/W2039453624","https://openalex.org/W2041715023","https://openalex.org/W2042880070","https://openalex.org/W2053339983","https://openalex.org/W2057511197","https://openalex.org/W2059312051","https://openalex.org/W2064867081","https://openalex.org/W2066292361","https://openalex.org/W2070587756","https://openalex.org/W2073293499","https://openalex.org/W2082536486","https://openalex.org/W2085667464","https://openalex.org/W2092610209","https://openalex.org/W2096245011","https://openalex.org/W2096525273","https://openalex.org/W2097210022","https://openalex.org/W2102653059","https://openalex.org/W2107062718","https://openalex.org/W2111807512","https://openalex.org/W2113777491","https://openalex.org/W2115343689","https://openalex.org/W2117364474","https://openalex.org/W2128539422","https://openalex.org/W2128601422","https://openalex.org/W2140157849","https://openalex.org/W2141776893","https://openalex.org/W2147472054","https://openalex.org/W2150583791","https://openalex.org/W2150908245","https://openalex.org/W2154146690","https://openalex.org/W2159482845","https://openalex.org/W2159628188","https://openalex.org/W2160594875","https://openalex.org/W2160751597","https://openalex.org/W2161304688","https://openalex.org/W2168152236","https://openalex.org/W2605068739","https://openalex.org/W3144853201","https://openalex.org/W4212920271","https://openalex.org/W4230392683","https://openalex.org/W4238101851","https://openalex.org/W4238701569","https://openalex.org/W4244606935","https://openalex.org/W4294216483"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2748952813","https://openalex.org/W2944823289","https://openalex.org/W2003209439","https://openalex.org/W4321854979","https://openalex.org/W3037018281","https://openalex.org/W2358319515","https://openalex.org/W2972592048","https://openalex.org/W4312214821","https://openalex.org/W4361862506"],"abstract_inverted_index":{"BACKGROUND:":[0],"The":[1],"kinetic":[2,37,46,107,205,218,271],"modeling":[3],"of":[4,10,59,72,105,132,147,154,222,269],"biological":[5],"systems":[6,116,174,229,254],"is":[7,26,110,137,236,285],"mainly":[8],"composed":[9],"three":[11],"steps":[12,104],"that":[13,141,240],"proceed":[14],"iteratively:":[15],"model":[16,219],"building,":[17],"simulation":[18],"and":[19,34,156,158,169,184,195,202,245,264,273],"analysis.":[20],"In":[21,95],"the":[22,56,77,103,115,129,209,217,228,253],"first":[23],"step,":[24],"it":[25,200],"usually":[27,83],"required":[28],"to":[29,35,85,97,164,187,215],"set":[30],"initial":[31],"metabolite":[32],"concentrations,":[33],"assign":[36],"rate":[38],"laws,":[39],"along":[40,293],"with":[41,125,208,249,257,294],"estimating":[42],"parameter":[43],"values":[44],"using":[45,280],"data":[47,79,122,145,153,166,190,197,244,262],"through":[48],"optimization":[49],"when":[50,227],"these":[51],"are":[52,81],"not":[53,82,91],"known.":[54],"Although":[55],"rapid":[57],"development":[58],"high-throughput":[60],"methods":[61],"has":[62],"generated":[63],"much":[64,100],"omics":[65],"data,":[66,150],"experimentalists":[67],"present":[68],"only":[69],"a":[70,111,138,143,172,181,237,242,258],"summary":[71],"obtained":[73],"results":[74],"for":[75,119,171,288],"publication,":[76],"experimental":[78,149],"files":[80],"submitted":[84],"any":[86],"public":[87,144,243],"repository,":[88],"or":[89],"simply":[90],"available":[92,189,204,287],"at":[93,291],"all.":[94],"order":[96],"automatize":[98],"as":[99,101],"possible":[102],"building":[106],"models,":[108,126],"there":[109],"growing":[112],"requirement":[113],"in":[114,123],"biology":[117,175,255],"community":[118,178,256],"easily":[120],"exchanging":[121],"combination":[124],"which":[127],"represents":[128],"main":[130],"motivation":[131],"KiMoSys":[133,136,235],"development.":[134],"DESCRIPTION:":[135],"user-friendly":[139],"platform":[140],"includes":[142],"repository":[146,179,248],"published":[148],"containing":[151],"concentration":[152],"metabolites":[155],"enzymes":[157],"flux":[159],"data.":[160],"It":[161],"was":[162],"designed":[163],"ensure":[165],"management,":[167],"storage":[168,263],"sharing":[170],"wider":[173],"community.":[176],"This":[177],"offers":[180],"web-based":[182,238],"interface":[183],"upload":[185],"facility":[186],"turn":[188],"into":[191],"publicly":[192],"accessible,":[193],"centralized":[194],"structured-format":[196],"files.":[198],"Moreover,":[199],"compiles":[201],"integrates":[203,212,241],"models":[206,272],"associated":[207,246],"data.KiMoSys":[210],"also":[211],"some":[213],"tools":[214],"facilitate":[216],"construction":[220,268],"process":[221],"large-scale":[223],"metabolic":[224],"networks,":[225],"especially":[226],"biologists":[230],"perform":[231],"computational":[232,250],"research.":[233],"CONCLUSIONS:":[234],"system":[239],"model(s)":[247],"tools,":[251],"providing":[252],"novel":[259],"application":[260,278],"facilitating":[261],"sharing,":[265],"thus":[266],"supporting":[267],"ODE-based":[270],"collaborative":[274],"research":[275],"projects.The":[276],"web":[277,289],"implemented":[279],"Ruby":[281],"on":[282],"Rails":[283],"framework":[284],"freely":[286],"access":[290],"http://kimosys.org,":[292],"its":[295],"full":[296],"documentation.":[297]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":1}],"updated_date":"2026-05-05T08:41:31.759640","created_date":"2025-10-10T00:00:00"}