{"id":"https://openalex.org/W7143925246","doi":"https://doi.org/10.1186/s12911-026-03445-w","title":"Nomogram for predicting 30-day mortality in patients with infective endocarditis: a retrospective study","display_name":"Nomogram for predicting 30-day mortality in patients with infective endocarditis: a retrospective study","publication_year":2026,"publication_date":"2026-03-31","ids":{"openalex":"https://openalex.org/W7143925246","doi":"https://doi.org/10.1186/s12911-026-03445-w","pmid":"https://pubmed.ncbi.nlm.nih.gov/41917954"},"language":"en","primary_location":{"id":"doi:10.1186/s12911-026-03445-w","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12911-026-03445-w","pdf_url":null,"source":{"id":"https://openalex.org/S107516304","display_name":"BMC Medical Informatics and Decision Making","issn_l":"1472-6947","issn":["1472-6947"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Informatics and Decision Making","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1186/s12911-026-03445-w","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5131089779","display_name":"Zhenzhen Cai","orcid":null},"institutions":[{"id":"https://openalex.org/I4210146612","display_name":"National Center for Clinical Laboratories","ror":"https://ror.org/0530d6n45","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210146612"]},{"id":"https://openalex.org/I83519826","display_name":"Nanjing Medical University","ror":"https://ror.org/059gcgy73","country_code":"CN","type":"education","lineage":["https://openalex.org/I83519826"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhenzhen Cai","raw_affiliation_strings":["Branch of National Clinical Research Center for Laboratory Medicine, Nanjing, Jiangsu, China","Department of Laboratory Medicine, The First Affiliated Hospital with Nanjing Medical University, Nanjing, Jiangsu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Branch of National Clinical Research Center for Laboratory Medicine, Nanjing, Jiangsu, China","institution_ids":["https://openalex.org/I4210146612"]},{"raw_affiliation_string":"Department of Laboratory Medicine, The First Affiliated Hospital with Nanjing Medical University, Nanjing, Jiangsu, China","institution_ids":["https://openalex.org/I83519826"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5131397038","display_name":"TingTing Song","orcid":null},"institutions":[{"id":"https://openalex.org/I177388780","display_name":"Xuzhou Medical College","ror":"https://ror.org/04fe7hy80","country_code":"CN","type":"education","lineage":["https://openalex.org/I177388780"]},{"id":"https://openalex.org/I4210095236","display_name":"Suizhou Central Hospital","ror":"https://ror.org/00q3p9p08","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210095236"]},{"id":"https://openalex.org/I4210143072","display_name":"Xuzhou No.1 People's Hospital","ror":"https://ror.org/05ca6eb43","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210143072"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"TingTing Song","raw_affiliation_strings":["Department of Obstetrics, The People's Hospital of Suining County, Xuzhou, Jiangsu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics, The People's Hospital of Suining County, Xuzhou, Jiangsu, China","institution_ids":["https://openalex.org/I4210143072","https://openalex.org/I177388780","https://openalex.org/I4210095236"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080490796","display_name":"Shengfeng Qiu","orcid":null},"institutions":[{"id":"https://openalex.org/I4210146612","display_name":"National Center for Clinical Laboratories","ror":"https://ror.org/0530d6n45","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210146612"]},{"id":"https://openalex.org/I83519826","display_name":"Nanjing Medical University","ror":"https://ror.org/059gcgy73","country_code":"CN","type":"education","lineage":["https://openalex.org/I83519826"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shengfeng Qiu","raw_affiliation_strings":["Branch of National Clinical Research Center for Laboratory Medicine, Nanjing, Jiangsu, China","Department of Laboratory Medicine, The First Affiliated Hospital with Nanjing Medical University, Nanjing, Jiangsu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Branch of National Clinical Research Center for Laboratory Medicine, Nanjing, Jiangsu, China","institution_ids":["https://openalex.org/I4210146612"]},{"raw_affiliation_string":"Department of Laboratory Medicine, The First Affiliated Hospital with Nanjing Medical University, Nanjing, Jiangsu, China","institution_ids":["https://openalex.org/I83519826"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5131348766","display_name":"Ning Dong","orcid":null},"institutions":[{"id":"https://openalex.org/I83519826","display_name":"Nanjing Medical University","ror":"https://ror.org/059gcgy73","country_code":"CN","type":"education","lineage":["https://openalex.org/I83519826"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ning Dong","raw_affiliation_strings":["Department of Quality Management, The First Affiliated Hospital with Nanjing Medical University, Nanjing, Jiangsu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Quality Management, The First Affiliated Hospital with Nanjing Medical University, Nanjing, Jiangsu, China","institution_ids":["https://openalex.org/I83519826"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5131244303","display_name":"Ting Wang","orcid":null},"institutions":[{"id":"https://openalex.org/I131434179","display_name":"Nanjing University of Chinese Medicine","ror":"https://ror.org/04523zj19","country_code":"CN","type":"education","lineage":["https://openalex.org/I131434179"]},{"id":"https://openalex.org/I83519826","display_name":"Nanjing Medical University","ror":"https://ror.org/059gcgy73","country_code":"CN","type":"education","lineage":["https://openalex.org/I83519826"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Ting Wang","raw_affiliation_strings":["Branch of National Clinical Research Center for Laboratory Medicine, Nanjing, Jiangsu, China. wangting0622@njmu.edu.cn","Department of Laboratory Medicine, The First Affiliated Hospital with Nanjing Medical University, Nanjing, Jiangsu, China. wangting0622@njmu.edu.cn"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Branch of National Clinical Research Center for Laboratory Medicine, Nanjing, Jiangsu, China. wangting0622@njmu.edu.cn","institution_ids":["https://openalex.org/I131434179"]},{"raw_affiliation_string":"Department of Laboratory Medicine, The First Affiliated Hospital with Nanjing Medical University, Nanjing, Jiangsu, China. wangting0622@njmu.edu.cn","institution_ids":["https://openalex.org/I83519826"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5131402009","display_name":"Jun ZHOU","orcid":null},"institutions":[{"id":"https://openalex.org/I4210159340","display_name":"The Synergetic Innovation Center for Advanced Materials","ror":"https://ror.org/05nzc1r88","country_code":"CN","type":"facility","lineage":["https://openalex.org/I134687103","https://openalex.org/I41198531","https://openalex.org/I4210159340","https://openalex.org/I76130692","https://openalex.org/I99065089"]},{"id":"https://openalex.org/I83519826","display_name":"Nanjing Medical University","ror":"https://ror.org/059gcgy73","country_code":"CN","type":"education","lineage":["https://openalex.org/I83519826"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jun Zhou","raw_affiliation_strings":["Branch of National Clinical Research Center for Laboratory Medicine, Nanjing, Jiangsu, China. zhoujun5958@163.com","Department of Laboratory Medicine, The First Affiliated Hospital with Nanjing Medical University, Nanjing, Jiangsu, China. zhoujun5958@163.com"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Branch of National Clinical Research Center for Laboratory Medicine, Nanjing, Jiangsu, China. zhoujun5958@163.com","institution_ids":["https://openalex.org/I4210159340"]},{"raw_affiliation_string":"Department of Laboratory Medicine, The First Affiliated Hospital with Nanjing Medical University, Nanjing, Jiangsu, China. zhoujun5958@163.com","institution_ids":["https://openalex.org/I83519826"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5131244303"],"corresponding_institution_ids":["https://openalex.org/I131434179","https://openalex.org/I83519826"],"apc_list":{"value":1570,"currency":"GBP","value_usd":1925},"apc_paid":{"value":1570,"currency":"GBP","value_usd":1925},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.43457494,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"26","issue":"1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11551","display_name":"Infective Endocarditis Diagnosis and Management","score":0.9574999809265137,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11551","display_name":"Infective Endocarditis Diagnosis and Management","score":0.9574999809265137,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10195","display_name":"Antimicrobial Resistance in Staphylococcus","score":0.004399999976158142,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12600","display_name":"Eosinophilic Disorders and Syndromes","score":0.0027000000700354576,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nomogram","display_name":"Nomogram","score":0.8438000082969666},{"id":"https://openalex.org/keywords/retrospective-cohort-study","display_name":"Retrospective cohort study","score":0.7940999865531921},{"id":"https://openalex.org/keywords/health-informatics","display_name":"Health informatics","score":0.5080999732017517},{"id":"https://openalex.org/keywords/proportional-hazards-model","display_name":"Proportional hazards model","score":0.3244999945163727},{"id":"https://openalex.org/keywords/medline","display_name":"MEDLINE","score":0.3059999942779541}],"concepts":[{"id":"https://openalex.org/C34626388","wikidata":"https://www.wikidata.org/wiki/Q721129","display_name":"Nomogram","level":2,"score":0.8438000082969666},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.7940999865531921},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7814000248908997},{"id":"https://openalex.org/C145642194","wikidata":"https://www.wikidata.org/wiki/Q870895","display_name":"Health informatics","level":3,"score":0.5080999732017517},{"id":"https://openalex.org/C194828623","wikidata":"https://www.wikidata.org/wiki/Q2861470","display_name":"Emergency medicine","level":1,"score":0.42800000309944153},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.38100001215934753},{"id":"https://openalex.org/C50382708","wikidata":"https://www.wikidata.org/wiki/Q223218","display_name":"Proportional hazards model","level":2,"score":0.3244999945163727},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.3059999942779541},{"id":"https://openalex.org/C3018822202","wikidata":"https://www.wikidata.org/wiki/Q1324077","display_name":"Patient data","level":2,"score":0.3046000003814697},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2883000075817108},{"id":"https://openalex.org/C545542383","wikidata":"https://www.wikidata.org/wiki/Q2751242","display_name":"Medical emergency","level":1,"score":0.2565000057220459},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.25529998540878296}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1186/s12911-026-03445-w","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12911-026-03445-w","pdf_url":null,"source":{"id":"https://openalex.org/S107516304","display_name":"BMC Medical Informatics and Decision Making","issn_l":"1472-6947","issn":["1472-6947"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Informatics and Decision Making","raw_type":"journal-article"},{"id":"pmid:41917954","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41917954","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC medical informatics and decision making","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:13162416","is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13162416/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13162416/pdf/12911_2026_Article_3445.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Med Inform Decis Mak","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:089dfef0d9d34371a12ea685476e51fb","is_oa":true,"landing_page_url":"https://doaj.org/article/089dfef0d9d34371a12ea685476e51fb","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Medical Informatics and Decision Making, Vol 26, Iss 1 (2026)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/s12911-026-03445-w","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12911-026-03445-w","pdf_url":null,"source":{"id":"https://openalex.org/S107516304","display_name":"BMC Medical Informatics and Decision Making","issn_l":"1472-6947","issn":["1472-6947"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Informatics and Decision Making","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.7045688629150391,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320321605","display_name":"Government of Jiangsu Province","ror":"https://ror.org/004svx814"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":15,"referenced_works":["https://openalex.org/W2064039435","https://openalex.org/W2223150550","https://openalex.org/W2904639918","https://openalex.org/W3014124212","https://openalex.org/W3139099468","https://openalex.org/W3194841544","https://openalex.org/W3212841034","https://openalex.org/W4328127671","https://openalex.org/W4368359961","https://openalex.org/W4386153816","https://openalex.org/W4387033012","https://openalex.org/W4393233287","https://openalex.org/W4399353029","https://openalex.org/W4405734977","https://openalex.org/W4411001291"],"related_works":[],"abstract_inverted_index":{"BACKGROUND:":[0],"The":[1,152,208],"prognosis":[2,204],"for":[3,18,98,220],"patients":[4,26,42,53,73],"with":[5,44],"infective":[6],"endocarditis":[7],"(IE)":[8],"remains":[9],"suboptimal.":[10],"This":[11],"study":[12,39],"aimed":[13],"to":[14,28,57],"identify":[15],"risk":[16,150,209,225],"factors":[17,215],"30-day":[19,83,223],"mortality":[20,224],"after":[21],"hospital":[22],"admission":[23],"in":[24,65,160,166,205,226],"IE":[25,45,206,228],"and":[27,49,61,78,88,93,101,118,143,164,177,180,198],"construct":[29],"a":[30,37,58,62,66],"prognostic":[31],"prediction":[32,102,210],"model.":[33],"METHODS:":[34],"We":[35],"conducted":[36],"retrospective":[38],"of":[40,158,203],"391":[41],"diagnosed":[43],"between":[46,175],"January":[47],"2017":[48],"September":[50],"2024.":[51],"Enrolled":[52],"were":[54,74,96,146],"randomly":[55],"allocated":[56],"training":[59,71,162],"cohort":[60,64,163],"validation":[63,168],"7:3":[67],"ratio.":[68],"Within":[69],"the":[70,110,113,161,167,183,222],"cohort,":[72],"stratified":[75],"into":[76],"survival":[77],"non-survival":[79],"groups":[80],"based":[81],"on":[82],"outcomes.":[84],"Least":[85],"Absolute":[86],"Shrinkage":[87],"Selection":[89],"Operator":[90],"(LASSO)":[91],"regression":[92,95],"logistic":[94],"employed":[97],"feature":[99],"selection":[100],"model":[103,154,211],"construction.":[104],"Model":[105],"performance":[106],"was":[107],"evaluated":[108],"using":[109],"area":[111],"under":[112],"curve":[114,120],"(AUC),":[115],"calibration":[116],"curves,":[117],"decision":[119],"analysis":[121],"(DCA).":[122],"RESULTS:":[123],"Surgical,":[124,193],"lower":[125],"lymphocyte":[126],"count":[127],"(LY),":[128],"prolonged":[129],"activated":[130],"partial":[131],"thromboplastin":[132],"time":[133],"(APTT),":[134],"higher":[135,139,144],"lactate":[136],"dehydrogenase":[137],"(LDH),":[138],"creatine":[140],"kinase":[141],"(CK),":[142],"UREA":[145,199],"identified":[147],"as":[148],"independent":[149],"factors.":[151],"nomogram":[153],"demonstrated":[155],"an":[156],"AUC":[157],"0.889":[159],"0.783":[165],"cohort.":[169],"Calibration":[170],"curves":[171],"showed":[172],"excellent":[173],"alignment":[174],"predicted":[176],"actual":[178],"outcomes,":[179],"DCA":[181],"confirmed":[182],"model\u2019s":[184],"positive":[185],"net":[186],"clinical":[187,218],"benefit":[188],"across":[189],"reasonable":[190],"thresholds.":[191],"CONCLUSIONS:":[192],"LY,":[194],"APTT,":[195],"LDH,":[196],"CK,":[197],"are":[200],"significant":[201],"predictors":[202],"patients.":[207,229],"constructed":[212],"from":[213],"these":[214],"shows":[216],"high":[217],"utility":[219],"assessing":[221],"hospitalized":[227]},"counts_by_year":[],"updated_date":"2026-06-16T09:24:06.705377","created_date":"2026-04-01T00:00:00"}