{"id":"https://openalex.org/W4401911683","doi":"https://doi.org/10.1186/s12911-024-02631-y","title":"Optimizing protein sequence classification: integrating deep learning models with Bayesian optimization for enhanced biological analysis","display_name":"Optimizing protein sequence classification: integrating deep learning models with Bayesian optimization for enhanced biological analysis","publication_year":2024,"publication_date":"2024-08-27","ids":{"openalex":"https://openalex.org/W4401911683","doi":"https://doi.org/10.1186/s12911-024-02631-y","pmid":"https://pubmed.ncbi.nlm.nih.gov/39192227"},"language":"en","primary_location":{"id":"doi:10.1186/s12911-024-02631-y","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12911-024-02631-y","pdf_url":"https://bmcmedinformdecismak.biomedcentral.com/counter/pdf/10.1186/s12911-024-02631-y","source":{"id":"https://openalex.org/S107516304","display_name":"BMC Medical Informatics and Decision Making","issn_l":"1472-6947","issn":["1472-6947"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Informatics and Decision Making","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcmedinformdecismak.biomedcentral.com/counter/pdf/10.1186/s12911-024-02631-y","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5039191048","display_name":"Umesh Kumar Lilhore","orcid":"https://orcid.org/0000-0001-6073-3773"},"institutions":[{"id":"https://openalex.org/I155125381","display_name":"Galgotias University","ror":"https://ror.org/02w8ba206","country_code":"IN","type":"education","lineage":["https://openalex.org/I155125381"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Umesh Kumar Lilhore","raw_affiliation_strings":["School of Computing Science and Engineering, Galgotias University, Greater Noida, UP, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Computing Science and Engineering, Galgotias University, Greater Noida, UP, India","institution_ids":["https://openalex.org/I155125381"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5106755662","display_name":"Sarita Simiaya","orcid":null},"institutions":[{"id":"https://openalex.org/I155125381","display_name":"Galgotias University","ror":"https://ror.org/02w8ba206","country_code":"IN","type":"education","lineage":["https://openalex.org/I155125381"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Sarita Simiaya","raw_affiliation_strings":["School of Computing Science and Engineering, Galgotias University, Greater Noida, UP, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Computing Science and Engineering, Galgotias University, Greater Noida, UP, India","institution_ids":["https://openalex.org/I155125381"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052648906","display_name":"Musaed Alhussein","orcid":"https://orcid.org/0000-0002-5538-6778"},"institutions":[{"id":"https://openalex.org/I28022161","display_name":"King Saud University","ror":"https://ror.org/02f81g417","country_code":"SA","type":"education","lineage":["https://openalex.org/I28022161"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Musaed Alhussein","raw_affiliation_strings":["Department of Computer Engineering, College of Computer and Information Sciences, King Saud University, P. O. Box 51178, Riyadh, 11543, Saudi Arabia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Engineering, College of Computer and Information Sciences, King Saud University, P. O. Box 51178, Riyadh, 11543, Saudi Arabia","institution_ids":["https://openalex.org/I28022161"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049378581","display_name":"Neetu Faujdar","orcid":"https://orcid.org/0000-0002-1482-9755"},"institutions":[{"id":"https://openalex.org/I82571370","display_name":"GLA University","ror":"https://ror.org/05fnxgv12","country_code":"IN","type":"education","lineage":["https://openalex.org/I82571370"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Neetu Faujdar","raw_affiliation_strings":["Department of Computer Engineering and Applications, GLA University, 281406, UP, Mathura, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Engineering and Applications, GLA University, 281406, UP, Mathura, India","institution_ids":["https://openalex.org/I82571370"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084092269","display_name":"Surjeet Dalal","orcid":"https://orcid.org/0000-0002-4325-9237"},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Surjeet Dalal","raw_affiliation_strings":["Amity University, Gurugram Haryana, India. sdalal@ggn.amity.edu","Amity University, Gurugram Haryana, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Amity University, Gurugram Haryana, India. sdalal@ggn.amity.edu","institution_ids":[]},{"raw_affiliation_string":"Amity University, Gurugram Haryana, India","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5014562556","display_name":"Khursheed Aurangzeb","orcid":"https://orcid.org/0000-0003-3647-8578"},"institutions":[{"id":"https://openalex.org/I28022161","display_name":"King Saud University","ror":"https://ror.org/02f81g417","country_code":"SA","type":"education","lineage":["https://openalex.org/I28022161"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Khursheed Aurangzeb","raw_affiliation_strings":["Department of Computer Engineering, College of Computer and Information Sciences, King Saud University, P. O. Box 51178, Riyadh, 11543, Saudi Arabia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Engineering, College of Computer and Information Sciences, King Saud University, P. O. Box 51178, Riyadh, 11543, Saudi Arabia","institution_ids":["https://openalex.org/I28022161"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5084092269"],"corresponding_institution_ids":[],"apc_list":{"value":2690,"currency":"USD","value_usd":2690},"apc_paid":{"value":2690,"currency":"USD","value_usd":2690},"fwci":1.9715,"has_fulltext":true,"cited_by_count":12,"citation_normalized_percentile":{"value":0.86732665,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":98,"max":99},"biblio":{"volume":"24","issue":"1","first_page":"236","last_page":"236"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9941999912261963,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13937","display_name":"Genetics, Bioinformatics, and Biomedical Research","score":0.9937999844551086,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7642035484313965},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.6421980261802673},{"id":"https://openalex.org/keywords/convolutional-neural-network","display_name":"Convolutional neural network","score":0.6202645301818848},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.5848242044448853},{"id":"https://openalex.org/keywords/robustness","display_name":"Robustness (evolution)","score":0.5483969449996948},{"id":"https://openalex.org/keywords/hyperparameter","display_name":"Hyperparameter","score":0.4870772659778595},{"id":"https://openalex.org/keywords/sequence","display_name":"Sequence (biology)","score":0.47803908586502075},{"id":"https://openalex.org/keywords/protein-sequencing","display_name":"Protein sequencing","score":0.43806692957878113},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.4347509443759918},{"id":"https://openalex.org/keywords/categorization","display_name":"Categorization","score":0.42743897438049316}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7642035484313965},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.6421980261802673},{"id":"https://openalex.org/C81363708","wikidata":"https://www.wikidata.org/wiki/Q17084460","display_name":"Convolutional neural network","level":2,"score":0.6202645301818848},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.5848242044448853},{"id":"https://openalex.org/C63479239","wikidata":"https://www.wikidata.org/wiki/Q7353546","display_name":"Robustness (evolution)","level":3,"score":0.5483969449996948},{"id":"https://openalex.org/C8642999","wikidata":"https://www.wikidata.org/wiki/Q4171168","display_name":"Hyperparameter","level":2,"score":0.4870772659778595},{"id":"https://openalex.org/C2778112365","wikidata":"https://www.wikidata.org/wiki/Q3511065","display_name":"Sequence (biology)","level":2,"score":0.47803908586502075},{"id":"https://openalex.org/C10010492","wikidata":"https://www.wikidata.org/wiki/Q3142557","display_name":"Protein sequencing","level":4,"score":0.43806692957878113},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.4347509443759918},{"id":"https://openalex.org/C94124525","wikidata":"https://www.wikidata.org/wiki/Q912550","display_name":"Categorization","level":2,"score":0.42743897438049316},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C167625842","wikidata":"https://www.wikidata.org/wiki/Q899763","display_name":"Peptide sequence","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001499","descriptor_name":"Bayes Theorem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001499","descriptor_name":"Bayes Theorem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001499","descriptor_name":"Bayes Theorem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001499","descriptor_name":"Bayes Theorem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001499","descriptor_name":"Bayes Theorem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020539","descriptor_name":"Sequence Analysis, Protein","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020539","descriptor_name":"Sequence Analysis, Protein","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020539","descriptor_name":"Sequence Analysis, Protein","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020539","descriptor_name":"Sequence Analysis, Protein","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020539","descriptor_name":"Sequence Analysis, Protein","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1186/s12911-024-02631-y","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12911-024-02631-y","pdf_url":"https://bmcmedinformdecismak.biomedcentral.com/counter/pdf/10.1186/s12911-024-02631-y","source":{"id":"https://openalex.org/S107516304","display_name":"BMC Medical Informatics and Decision Making","issn_l":"1472-6947","issn":["1472-6947"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Informatics and Decision Making","raw_type":"journal-article"},{"id":"pmid:39192227","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39192227","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC medical informatics and decision making","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:11351277","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11351277","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11351277/pdf/12911_2024_Article_2631.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Med Inform Decis Mak","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:5c0bb4ee34824bf2a28f965df7882e64","is_oa":true,"landing_page_url":"https://doaj.org/article/5c0bb4ee34824bf2a28f965df7882e64","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Medical Informatics and Decision Making, Vol 24, Iss 1, Pp 1-16 (2024)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/s12911-024-02631-y","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12911-024-02631-y","pdf_url":"https://bmcmedinformdecismak.biomedcentral.com/counter/pdf/10.1186/s12911-024-02631-y","source":{"id":"https://openalex.org/S107516304","display_name":"BMC Medical Informatics and Decision Making","issn_l":"1472-6947","issn":["1472-6947"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Informatics and Decision Making","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G7317261082","display_name":null,"funder_award_id":"RSPD2024R553","funder_id":"https://openalex.org/F4320321145","funder_display_name":"King Saud University"},{"id":"https://openalex.org/G8253845591","display_name":null,"funder_award_id":"RSPD2024R553","funder_id":"https://openalex.org/F4320331156","funder_display_name":"King Faisal University"}],"funders":[{"id":"https://openalex.org/F4320321145","display_name":"King Saud University","ror":"https://ror.org/02f81g417"},{"id":"https://openalex.org/F4320331156","display_name":"King Faisal University","ror":null}],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W4401911683.pdf"},"referenced_works_count":49,"referenced_works":["https://openalex.org/W2296242593","https://openalex.org/W2359716859","https://openalex.org/W2624968853","https://openalex.org/W2766119845","https://openalex.org/W2797060233","https://openalex.org/W2807929272","https://openalex.org/W2883380892","https://openalex.org/W2890132714","https://openalex.org/W2910573996","https://openalex.org/W2914877211","https://openalex.org/W2931503046","https://openalex.org/W2945297971","https://openalex.org/W2957180077","https://openalex.org/W2966164316","https://openalex.org/W2973993756","https://openalex.org/W3000260630","https://openalex.org/W3014987848","https://openalex.org/W3021338900","https://openalex.org/W3035772797","https://openalex.org/W3088717585","https://openalex.org/W3093120804","https://openalex.org/W3110692511","https://openalex.org/W3115890771","https://openalex.org/W3128687311","https://openalex.org/W3129125493","https://openalex.org/W3139240024","https://openalex.org/W3216811210","https://openalex.org/W3217203425","https://openalex.org/W4200599415","https://openalex.org/W4213048371","https://openalex.org/W4214656865","https://openalex.org/W4283397333","https://openalex.org/W4290989027","https://openalex.org/W4309908754","https://openalex.org/W4311661986","https://openalex.org/W4316363330","https://openalex.org/W4317369987","https://openalex.org/W4321440624","https://openalex.org/W4322625529","https://openalex.org/W4324128859","https://openalex.org/W4366607338","https://openalex.org/W4389117224","https://openalex.org/W4389166162","https://openalex.org/W4389371539","https://openalex.org/W4390946589","https://openalex.org/W4391057469","https://openalex.org/W4391131105","https://openalex.org/W4391647565","https://openalex.org/W4394720053"],"related_works":["https://openalex.org/W2140186469","https://openalex.org/W4390421286","https://openalex.org/W2165912799","https://openalex.org/W4280563792","https://openalex.org/W4389724018","https://openalex.org/W4318719684","https://openalex.org/W2735662278","https://openalex.org/W4206951940","https://openalex.org/W4382602594","https://openalex.org/W4387850423"],"abstract_inverted_index":{"Efforts":[0],"to":[1,51,75,94],"enhance":[2],"the":[3,53,68,85,88,176],"accuracy":[4,54],"of":[5,10,55,70,146,157],"protein":[6,56,81,130,161,180,194],"sequence":[7,57,82,103,150,162,181,195],"classification":[8,58,196],"are":[9],"utmost":[11],"importance":[12],"in":[13],"driving":[14],"forward":[15,105],"biological":[16,110,171,190,206],"analyses":[17],"and":[18,39,72,79,106,119,128,143,148,189,203],"facilitating":[19],"significant":[20],"medical":[21,188],"advancements.":[22],"This":[23,183],"study":[24,165],"presents":[25],"a":[26],"cutting-edge":[27],"model":[28,115,122,178,197],"called":[29],"ProtICNN-BiLSTM,":[30],"which":[31],"combines":[32,67],"attention-based":[33],"Improved":[34],"Convolutional":[35],"Neural":[36],"Networks":[37],"(ICNN)":[38],"Bidirectional":[40],"Long":[41],"Short-Term":[42],"Memory":[43],"(BiLSTM)":[44],"units":[45],"seamlessly.":[46],"Our":[47],"main":[48],"goal":[49],"is":[50,198],"improve":[52,179,187],"by":[59,101],"carefully":[60],"optimizing":[61],"performance":[62],"through":[63],"Bayesian":[64,112,140,200],"Optimisation.":[65],"ProtICNN-BiLSTM":[66,135,158,177],"power":[69],"CNN":[71],"BiLSTM":[73,204],"architectures":[74],"effectively":[76],"capture":[77],"local":[78,96,147],"global":[80,149],"dependencies.":[83],"In":[84,108],"proposed":[86],"model,":[87],"ICNN":[89],"component":[90],"uses":[91],"convolutional":[92],"operations":[93],"identify":[95],"patterns.":[97],"Captures":[98],"long-range":[99],"associations":[100],"analyzing":[102],"data":[104,207],"backwards.":[107],"advanced":[109],"studies,":[111],"Optimisation":[113],"optimizes":[114],"hyperparameters":[116],"for":[117,169],"efficiency":[118],"robustness.":[120],"The":[121,155,164,192],"was":[123],"extensively":[124],"confirmed":[125],"with":[126],"PDB-14,189":[127],"other":[129],"data.":[131],"We":[132],"found":[133],"that":[134],"outperforms":[136],"traditional":[137],"categorization":[138],"models.":[139],"Optimization's":[141],"fine-tuning":[142],"seamless":[144],"integration":[145],"information":[151],"make":[152],"it":[153],"effective.":[154],"precision":[156],"improves":[159,166],"comparative":[160],"categorization.":[163,182],"computational":[167],"bioinformatics":[168],"complex":[170],"analysis.":[172],"Good":[173],"results":[174],"from":[175],"powerful":[184],"tool":[185],"could":[186],"research.":[191],"breakthrough":[193],"ProtICNN-BiLSTM.":[199],"optimization,":[201],"ICNN,":[202],"analyze":[205],"accurately.":[208]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":8}],"updated_date":"2026-07-23T08:03:31.855105","created_date":"2025-10-10T00:00:00"}