{"id":"https://openalex.org/W3088790314","doi":"https://doi.org/10.1186/s12911-020-01242-7","title":"Identification of plasma lipid species as promising diagnostic markers for prostate cancer","display_name":"Identification of plasma lipid species as promising diagnostic markers for prostate cancer","publication_year":2020,"publication_date":"2020-09-01","ids":{"openalex":"https://openalex.org/W3088790314","doi":"https://doi.org/10.1186/s12911-020-01242-7","mag":"3088790314","pmid":"https://pubmed.ncbi.nlm.nih.gov/32967667"},"language":"en","primary_location":{"id":"doi:10.1186/s12911-020-01242-7","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12911-020-01242-7","pdf_url":"https://bmcmedinformdecismak.biomedcentral.com/track/pdf/10.1186/s12911-020-01242-7","source":{"id":"https://openalex.org/S107516304","display_name":"BMC Medical Informatics and Decision Making","issn_l":"1472-6947","issn":["1472-6947"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Informatics and Decision Making","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcmedinformdecismak.biomedcentral.com/track/pdf/10.1186/s12911-020-01242-7","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5044240389","display_name":"Xiaoli Chen","orcid":"https://orcid.org/0000-0001-7327-4860"},"institutions":[{"id":"https://openalex.org/I1285301757","display_name":"Rush University Medical Center","ror":"https://ror.org/01j7c0b24","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285301757"]},{"id":"https://openalex.org/I4210134448","display_name":"Fourth Affiliated Hospital of Guangxi Medical University","ror":"https://ror.org/0335pr187","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210134448"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Xiaoli Chen","raw_affiliation_strings":["Department of Medicine, Rush University Medical Center, Chicago, IL, USA","Medical Science Laboratory, the Fourth Affiliated Hospital of Guangxi Medical University, Liuzhou, Guangxi, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Rush University Medical Center, Chicago, IL, USA","institution_ids":["https://openalex.org/I1285301757"]},{"raw_affiliation_string":"Medical Science Laboratory, the Fourth Affiliated Hospital of Guangxi Medical University, Liuzhou, Guangxi, China","institution_ids":["https://openalex.org/I4210134448"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023042484","display_name":"Yong Zhu","orcid":"https://orcid.org/0000-0002-0772-2474"},"institutions":[{"id":"https://openalex.org/I1285301757","display_name":"Rush University Medical Center","ror":"https://ror.org/01j7c0b24","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285301757"]},{"id":"https://openalex.org/I131434179","display_name":"Nanjing University of Chinese Medicine","ror":"https://ror.org/04523zj19","country_code":"CN","type":"education","lineage":["https://openalex.org/I131434179"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Yong Zhu","raw_affiliation_strings":["Department of Medicine, Rush University Medical Center, Chicago, IL, USA","National Medical Centre of Colorectal Disease, The Third Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Rush University Medical Center, Chicago, IL, USA","institution_ids":["https://openalex.org/I1285301757"]},{"raw_affiliation_string":"National Medical Centre of Colorectal Disease, The Third Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, P. R. China","institution_ids":["https://openalex.org/I131434179"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075017895","display_name":"Mayumi Jijiwa","orcid":"https://orcid.org/0000-0003-1596-856X"},"institutions":[{"id":"https://openalex.org/I117965899","display_name":"University of Hawai\u02bbi at M\u0101noa","ror":"https://ror.org/01wspgy28","country_code":"US","type":"education","lineage":["https://openalex.org/I117965899"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Mayumi Jijiwa","raw_affiliation_strings":["Bioinformatics Core, Department of Quantitative Health Sciences, University of Hawaii John A. Burns School of Medicine, Honolulu, HI, USA. jijiwa@hawaii.edu","Bioinformatics Core, Department of Quantitative Health Sciences, University of Hawaii John A. Burns School of Medicine, Honolulu, HI, USA"],"raw_orcid":"https://orcid.org/0000-0003-1596-856X","affiliations":[{"raw_affiliation_string":"Bioinformatics Core, Department of Quantitative Health Sciences, University of Hawaii John A. Burns School of Medicine, Honolulu, HI, USA. jijiwa@hawaii.edu","institution_ids":["https://openalex.org/I117965899"]},{"raw_affiliation_string":"Bioinformatics Core, Department of Quantitative Health Sciences, University of Hawaii John A. Burns School of Medicine, Honolulu, HI, USA","institution_ids":["https://openalex.org/I117965899"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113811481","display_name":"Masaki Nasu","orcid":null},"institutions":[{"id":"https://openalex.org/I117965899","display_name":"University of Hawai\u02bbi at M\u0101noa","ror":"https://ror.org/01wspgy28","country_code":"US","type":"education","lineage":["https://openalex.org/I117965899"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Masaki Nasu","raw_affiliation_strings":["Bioinformatics Core, Department of Quantitative Health Sciences, University of Hawaii John A. Burns School of Medicine, Honolulu, HI, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioinformatics Core, Department of Quantitative Health Sciences, University of Hawaii John A. Burns School of Medicine, Honolulu, HI, USA","institution_ids":["https://openalex.org/I117965899"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037028141","display_name":"Junmei Ai","orcid":null},"institutions":[{"id":"https://openalex.org/I1285301757","display_name":"Rush University Medical Center","ror":"https://ror.org/01j7c0b24","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285301757"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Junmei Ai","raw_affiliation_strings":["Department of Medicine, Rush University Medical Center, Chicago, IL, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Rush University Medical Center, Chicago, IL, USA","institution_ids":["https://openalex.org/I1285301757"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032073564","display_name":"Shengming Dai","orcid":"https://orcid.org/0000-0001-7398-3165"},"institutions":[{"id":"https://openalex.org/I117965899","display_name":"University of Hawai\u02bbi at M\u0101noa","ror":"https://ror.org/01wspgy28","country_code":"US","type":"education","lineage":["https://openalex.org/I117965899"]},{"id":"https://openalex.org/I4210134448","display_name":"Fourth Affiliated Hospital of Guangxi Medical University","ror":"https://ror.org/0335pr187","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210134448"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Shengming Dai","raw_affiliation_strings":["Bioinformatics Core, Department of Quantitative Health Sciences, University of Hawaii John A. Burns School of Medicine, Honolulu, HI, USA","Medical Science Laboratory, the Fourth Affiliated Hospital of Guangxi Medical University, Liuzhou, Guangxi, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioinformatics Core, Department of Quantitative Health Sciences, University of Hawaii John A. Burns School of Medicine, Honolulu, HI, USA","institution_ids":["https://openalex.org/I117965899"]},{"raw_affiliation_string":"Medical Science Laboratory, the Fourth Affiliated Hospital of Guangxi Medical University, Liuzhou, Guangxi, China","institution_ids":["https://openalex.org/I4210134448"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101744791","display_name":"Bin Jiang","orcid":"https://orcid.org/0000-0002-4622-9703"},"institutions":[{"id":"https://openalex.org/I131434179","display_name":"Nanjing University of Chinese Medicine","ror":"https://ror.org/04523zj19","country_code":"CN","type":"education","lineage":["https://openalex.org/I131434179"]},{"id":"https://openalex.org/I4210098580","display_name":"Nanjing Traditional Chinese Medicine Hospital","ror":"https://ror.org/016k98t76","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210098580"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Bin Jiang","raw_affiliation_strings":["National Medical Centre of Colorectal Disease, The Third Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, P. R. China. jbfirsth@aliyun.com","National Medical Centre of Colorectal Disease, The Third Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Medical Centre of Colorectal Disease, The Third Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, P. R. China. jbfirsth@aliyun.com","institution_ids":["https://openalex.org/I4210098580","https://openalex.org/I131434179"]},{"raw_affiliation_string":"National Medical Centre of Colorectal Disease, The Third Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, P. R. China","institution_ids":["https://openalex.org/I131434179"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101506002","display_name":"Jicai Zhang","orcid":"https://orcid.org/0000-0001-7098-7785"},"institutions":[{"id":"https://openalex.org/I1285929390","display_name":"Hubei University of Medicine","ror":"https://ror.org/01dr2b756","country_code":"CN","type":"education","lineage":["https://openalex.org/I1285929390"]},{"id":"https://openalex.org/I4210117378","display_name":"Taihe Hospital","ror":"https://ror.org/02ftdsn70","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210117378"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Jicai Zhang","raw_affiliation_strings":["Department of Laboratory Medicine, Shiyan Taihe Hospital, College of Biomedical Engineering, Hubei University of Medicine, Shiyan, Hubei, 442000, P. R. China. jicaizhang@taihehospital.com","Department of Laboratory Medicine, Shiyan Taihe Hospital, College of Biomedical Engineering, Hubei University of Medicine, Shiyan, Hubei, 442000, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Laboratory Medicine, Shiyan Taihe Hospital, College of Biomedical Engineering, Hubei University of Medicine, Shiyan, Hubei, 442000, P. R. China. jicaizhang@taihehospital.com","institution_ids":["https://openalex.org/I4210117378","https://openalex.org/I1285929390"]},{"raw_affiliation_string":"Department of Laboratory Medicine, Shiyan Taihe Hospital, College of Biomedical Engineering, Hubei University of Medicine, Shiyan, Hubei, 442000, P. R. China","institution_ids":["https://openalex.org/I1285929390","https://openalex.org/I4210117378"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100726056","display_name":"Gang Huang","orcid":null},"institutions":[{"id":"https://openalex.org/I4210135985","display_name":"Shanghai University of Medicine and Health Sciences","ror":"https://ror.org/03ns6aq57","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210135985"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Gang Huang","raw_affiliation_strings":["Shanghai Key Laboratory for Molecular Imaging, Shanghai University of Medicine and Health Sciences, Shanghai, 201318, P. R. China. huangg@sumhs.edu.cn","Shanghai Key Laboratory for Molecular Imaging, Shanghai University of Medicine and Health Sciences, Shanghai, 201318, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanghai Key Laboratory for Molecular Imaging, Shanghai University of Medicine and Health Sciences, Shanghai, 201318, P. R. China. huangg@sumhs.edu.cn","institution_ids":["https://openalex.org/I4210135985"]},{"raw_affiliation_string":"Shanghai Key Laboratory for Molecular Imaging, Shanghai University of Medicine and Health Sciences, Shanghai, 201318, P. R. China","institution_ids":["https://openalex.org/I4210135985"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5042435594","display_name":"Youping Deng","orcid":"https://orcid.org/0000-0002-5951-8213"},"institutions":[{"id":"https://openalex.org/I117965899","display_name":"University of Hawai\u02bbi at M\u0101noa","ror":"https://ror.org/01wspgy28","country_code":"US","type":"education","lineage":["https://openalex.org/I117965899"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Youping Deng","raw_affiliation_strings":["Bioinformatics Core, Department of Quantitative Health Sciences, University of Hawaii John A. Burns School of Medicine, Honolulu, HI, USA. dengy@hawaii.edu","Bioinformatics Core, Department of Quantitative Health Sciences, University of Hawaii John A. Burns School of Medicine, Honolulu, HI, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioinformatics Core, Department of Quantitative Health Sciences, University of Hawaii John A. Burns School of Medicine, Honolulu, HI, USA. dengy@hawaii.edu","institution_ids":["https://openalex.org/I117965899"]},{"raw_affiliation_string":"Bioinformatics Core, Department of Quantitative Health Sciences, University of Hawaii John A. Burns School of Medicine, Honolulu, HI, USA","institution_ids":["https://openalex.org/I117965899"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":10,"corresponding_author_ids":["https://openalex.org/A5075017895","https://openalex.org/A5100726056","https://openalex.org/A5101506002"],"corresponding_institution_ids":["https://openalex.org/I117965899","https://openalex.org/I1285929390","https://openalex.org/I4210117378","https://openalex.org/I4210135985"],"apc_list":{"value":1570,"currency":"GBP","value_usd":1925},"apc_paid":{"value":1570,"currency":"GBP","value_usd":1925},"fwci":1.1671,"has_fulltext":true,"cited_by_count":20,"citation_normalized_percentile":{"value":0.77995774,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":98},"biblio":{"volume":"20","issue":"S9","first_page":"223","last_page":"223"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10836","display_name":"Metabolomics and Mass Spectrometry Studies","score":0.5127999782562256,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10836","display_name":"Metabolomics and Mass Spectrometry Studies","score":0.5127999782562256,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12465","display_name":"Cancer, Lipids, and Metabolism","score":0.384799987077713,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10519","display_name":"Advanced Proteomics Techniques and Applications","score":0.011900000274181366,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/prostate-cancer","display_name":"Prostate cancer","score":0.9011282324790955},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.6042395234107971},{"id":"https://openalex.org/keywords/prostate","display_name":"Prostate","score":0.5444352626800537},{"id":"https://openalex.org/keywords/lipidomics","display_name":"Lipidomics","score":0.5381709933280945},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.5261670351028442},{"id":"https://openalex.org/keywords/kegg","display_name":"KEGG","score":0.5242405533790588},{"id":"https://openalex.org/keywords/biomarker","display_name":"Biomarker","score":0.4970302879810333},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.4792604446411133},{"id":"https://openalex.org/keywords/oncology","display_name":"Oncology","score":0.45688706636428833},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.3244621753692627},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.17447978258132935},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.13540872931480408},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.10181325674057007}],"concepts":[{"id":"https://openalex.org/C2780192828","wikidata":"https://www.wikidata.org/wiki/Q181257","display_name":"Prostate cancer","level":3,"score":0.9011282324790955},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6042395234107971},{"id":"https://openalex.org/C2776235491","wikidata":"https://www.wikidata.org/wiki/Q9625","display_name":"Prostate","level":3,"score":0.5444352626800537},{"id":"https://openalex.org/C58017582","wikidata":"https://www.wikidata.org/wiki/Q6556376","display_name":"Lipidomics","level":2,"score":0.5381709933280945},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.5261670351028442},{"id":"https://openalex.org/C152724338","wikidata":"https://www.wikidata.org/wiki/Q909442","display_name":"KEGG","level":5,"score":0.5242405533790588},{"id":"https://openalex.org/C2781197716","wikidata":"https://www.wikidata.org/wiki/Q864574","display_name":"Biomarker","level":2,"score":0.4970302879810333},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4792604446411133},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.45688706636428833},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3244621753692627},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.17447978258132935},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.13540872931480408},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.10181325674057007},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.0},{"id":"https://openalex.org/C162317418","wikidata":"https://www.wikidata.org/wiki/Q252857","display_name":"Transcriptome","level":4,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008055","descriptor_name":"Lipids","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D008055","descriptor_name":"Lipids","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D008055","descriptor_name":"Lipids","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D008055","descriptor_name":"Lipids","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D053858","descriptor_name":"Metabolic Networks and Pathways","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053858","descriptor_name":"Metabolic Networks and Pathways","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053858","descriptor_name":"Metabolic Networks and Pathways","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053858","descriptor_name":"Metabolic Networks and Pathways","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1186/s12911-020-01242-7","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12911-020-01242-7","pdf_url":"https://bmcmedinformdecismak.biomedcentral.com/track/pdf/10.1186/s12911-020-01242-7","source":{"id":"https://openalex.org/S107516304","display_name":"BMC Medical Informatics and Decision Making","issn_l":"1472-6947","issn":["1472-6947"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Informatics and Decision Making","raw_type":"journal-article"},{"id":"pmid:32967667","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32967667","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC medical informatics and decision making","raw_type":null},{"id":"pmh:oai:doaj.org/article:53ee070fa4464f14a694fc298b61dea5","is_oa":true,"landing_page_url":"https://doaj.org/article/53ee070fa4464f14a694fc298b61dea5","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Medical Informatics and Decision Making, Vol 20, Iss S9, Pp 1-10 (2020)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7513490","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7513490","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Med Inform Decis Mak","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/s12911-020-01242-7","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12911-020-01242-7","pdf_url":"https://bmcmedinformdecismak.biomedcentral.com/track/pdf/10.1186/s12911-020-01242-7","source":{"id":"https://openalex.org/S107516304","display_name":"BMC Medical Informatics and Decision Making","issn_l":"1472-6947","issn":["1472-6947"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Medical Informatics and Decision Making","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G2068627947","display_name":null,"funder_award_id":"2U54MD007601","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G4981486250","display_name":null,"funder_award_id":"5P30GM114737","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G6658495011","display_name":null,"funder_award_id":"5P20GM103466","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G8426551446","display_name":null,"funder_award_id":"5U54MD007584","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3088790314.pdf","grobid_xml":"https://content.openalex.org/works/W3088790314.grobid-xml"},"referenced_works_count":41,"referenced_works":["https://openalex.org/W348160472","https://openalex.org/W907174691","https://openalex.org/W1466540379","https://openalex.org/W1584878576","https://openalex.org/W1920469653","https://openalex.org/W1974054654","https://openalex.org/W1986648162","https://openalex.org/W1996195599","https://openalex.org/W2009503588","https://openalex.org/W2014349355","https://openalex.org/W2016388995","https://openalex.org/W2020140290","https://openalex.org/W2021889142","https://openalex.org/W2024341695","https://openalex.org/W2032555072","https://openalex.org/W2037881903","https://openalex.org/W2051408525","https://openalex.org/W2055636600","https://openalex.org/W2066377726","https://openalex.org/W2080561407","https://openalex.org/W2085418183","https://openalex.org/W2106377414","https://openalex.org/W2110571546","https://openalex.org/W2113009004","https://openalex.org/W2119732456","https://openalex.org/W2128365375","https://openalex.org/W2131623590","https://openalex.org/W2140687262","https://openalex.org/W2157240187","https://openalex.org/W2168788156","https://openalex.org/W2169611005","https://openalex.org/W2235523093","https://openalex.org/W2294472819","https://openalex.org/W2345645769","https://openalex.org/W2770892030","https://openalex.org/W2803361727","https://openalex.org/W2883245154","https://openalex.org/W2903272252","https://openalex.org/W2910505396","https://openalex.org/W2936702203","https://openalex.org/W2947368789"],"related_works":["https://openalex.org/W2017497567","https://openalex.org/W1964572291","https://openalex.org/W2804498896","https://openalex.org/W2091512523","https://openalex.org/W4387948744","https://openalex.org/W3015759778","https://openalex.org/W2088520467","https://openalex.org/W2075763133","https://openalex.org/W2376423713","https://openalex.org/W1583600832"],"abstract_inverted_index":{"BACKGROUND:":[0],"Prostate":[1],"cancer":[2,29,149,152,191],"is":[3,48],"a":[4,78,139],"very":[5],"common":[6],"and":[7,96,118,154,161,176,193,207],"highly":[8],"fatal":[9],"in":[10,108,187,238],"men.":[11],"Current":[12],"non-invasive":[13],"detection":[14,146],"methods":[15],"like":[16],"serum":[17],"biomarker":[18],"are":[19,30],"unsatisfactory.":[20],"Biomarkers":[21],"with":[22,86,91,197],"high":[23],"accuracy":[24],"for":[25,56,144],"diagnostic":[26,52],"of":[27,45,54,74,111,116,141,147,166,169,184,200,216,241],"prostate":[28,57,87,112,148,151,190,242],"urgently":[31],"needed.":[32],"Many":[33],"lipid":[34,234],"species":[35],"have":[36,236],"been":[37],"found":[38],"related":[39],"to":[40,49,101,125],"various":[41],"cancers.":[42],"The":[43,212],"purpose":[44],"our":[46],"study":[47,228],"explore":[50],"the":[51,103,109,127,145,155,158,167,194,217,223,231,239],"value":[53],"lipids":[55,76,104,135,172,186,219],"cancer.":[58,113,243],"RESULTS:":[59],"Using":[60],"triple":[61],"quadruple":[62],"liquid":[63],"chromatography":[64],"electrospray":[65],"ionization":[66],"tandem":[67],"mass":[68],"spectrometry,":[69],"we":[70],"performed":[71],"lipidomics":[72],"profiling":[73],"367":[75],"on":[77],"total":[79],"114":[80],"plasma":[81,233],"samples":[82],"from":[83],"30":[84],"patients":[85,90],"cancer,":[88],"38":[89],"benign":[92],"prostatic":[93],"hyperplasia":[94],"(BPH),":[95],"46":[97],"male":[98],"healthy":[99],"controls":[100],"evaluate":[102],"as":[105,138,222],"potential":[106,128,142,237],"biomarkers":[107,143,235],"diagnosis":[110,240],"Kyoto":[114],"Encyclopedia":[115],"Genes":[117],"Genomes":[119],"(KEGG)":[120],"pathway":[121,215],"database":[122],"was":[123,220],"used":[124],"construct":[126],"mechanism":[129],"pathway.":[130,225],"After":[131],"statistical":[132],"analysis,":[133],"five":[134,171,185],"were":[136,173],"identified":[137,181,232],"panel":[140,183],"between":[150,189],"group":[153,192,196],"BPH":[156],"group;":[157],"sensitivity,":[159],"specificity,":[160],"area":[162],"under":[163],"curve":[164],"(AUC)":[165],"combination":[168],"these":[170],"73.3,":[174],"81.6%,":[175],"0.800,":[177],"respectively.":[178,211],"We":[179],"also":[180],"another":[182],"distinguishing":[188],"control":[195],"predictive":[198],"values":[199],"sensitivity":[201],"at":[202,205,209],"76.7%,":[203],"specificity":[204],"80.4%,":[206],"AUC":[208],"0.836,":[210],"glycerophospholipid":[213],"metabolism":[214],"selected":[218],"considered":[221],"target":[224],"CONCLUSIONS:":[226],"Our":[227],"indicated":[229],"that":[230]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":5}],"updated_date":"2026-05-06T08:25:59.206177","created_date":"2025-10-10T00:00:00"}